subject area of

• A new family of the poly-deoxyadenylated class of Drosophila transposable elements identified by a representative member at the dunce locus  Academic Article
• A partial characterization of the cyclic nucleotide phosphodiesterases of Drosophila melanogaster  Academic Article
• An interchromosomal gene conversion of the Drosophila dunce locus identified with restriction site polymorphisms: a potential involvement of transposable elements in gene conversion  Academic Article
• Characterization of the first potent and selective PDE9 inhibitor using a cGMP reporter cell line  Academic Article
• Characterization of the memory gene dunce of Drosophila melanogaster  Academic Article
• Cloning and characterization of mammalian homologs of the Drosophila dunce+ gene  Academic Article
• Cloning and expression of cDNA for a human low-Km, rolipram-sensitive cyclic AMP phosphodiesterase  Academic Article
• Conditional rescue of the dunce learning/memory and female fertility defects with Drosophila or rat transgenes  Academic Article
• Cyclic AMP phosphodiesterases are localized in regions of the mouse brain associated with reinforcement, movement, and affect  Academic Article
• Defect in cyclic AMP phosphodiesterase due to the dunce mutation of learning in Drosophila melanogaster  Academic Article
• Drosophila cyclic nucleotide phosphodiesterases  Academic Article
• Dunce mutants of Drosophila melanogaster: mutants defective in the cyclic AMP phosphodiesterase enzyme system  Academic Article
• Evidence for domain organization within the 61-kDa calmodulin-dependent cyclic-nucleotide phosphodiesterase from bovine brain  Academic Article
• Genetic analysis of cyclic nucleotide phosphodiesterases in Drosophila melanogaster  Academic Article
• Genetic dissection of the learning/memory gene dunce of Drosophila melanogaster  Academic Article
• Genetic manipulation of cyclic AMP levels in Drosophila melanogaster  Academic Article
• Heavy-metals and adenosine cyclic 3',5'-monophosphate metabolism - possible relevance to heavy-metal toxicity  Academic Article
• Molecular analysis of cDNA clones and the corresponding genomic coding sequences of the Drosophila dunce+ gene, the structural gene for cAMP phosphodiesterase  Academic Article
• Mutational analysis of phosphodiesterase in Drosophila  Academic Article
• Practical asymmetric synthesis of a potent PDE4 inhibitor via stereoselective enolate alkylation of a chiral aryl-heteroaryl secondary tosylate  Academic Article
• Progress in understanding the Drosophila dnc locus  Academic Article
• Rat homologs of the Drosophila dunce gene code for cyclic AMP phosphodiesterases sensitive to rolipram and RO 20-1724  Academic Article
• The Drosophila dunce locus: learning and memory genes in the fly  Academic Article
• The cyclic AMP phosphodiesterase encoded by the Drosophila dunce gene is concentrated in the mushroom body neuropil  Academic Article
• The cyclic AMP system and Drosophila learning  Academic Article
• The influence of 8-Br 3', 5'-cyclic nucleotide analogs and of inhibitors of 3', 5'-cyclic nucleotide phosphodiesterase, on noradrenaline secretion and neuromuscular transmission in guinea-pig vas deferens  Academic Article
• The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 attenuates a scopolamine-induced deficit in a novel rodent attention task  Academic Article
• Time-dependent involvement of cAMP and cGMP in consolidation of object memory: Studies using selective phosphodiesterase type 2, 4 and 5 inhibitors  Academic Article