subject area of
- Acute-phase responses in transgenic mice with CNS overexpression of IL-1 receptor antagonist Academic Article
- Adenoviral gene transfer of the interleukin-1 receptor antagonist protein to human islets prevents IL-1 beta-induced b-cell impairment and activation of islet cell apoptosis in vitro Academic Article
- Adenoviral transduction of human osteoblastic cell cultures - a new perspective for gene therapy of bone diseases Academic Article
- Approaches to enhancing the retroviral transduction of human synoviocytes Academic Article
- Cd46-utilizing adenoviruses inhibit c/ebp beta-dependent expression of proinflammatory cytokines Academic Article
- Cell-adhesion molecules Academic Article
- Chemical and enzymatic-synthesis of multivalent sialoglycopeptides Academic Article
- Chemokine expression by intraepithelial gamma delta t cells - implications for the recruitment of inflammatory cells to damaged epithelia Academic Article
- Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic cytokine gene to human joints with rheumatoid arthritis Academic Article
- Clinical trials in the gene therapy of arthritis Academic Article
- Cytokine-stimulated, but not HIV-infected, human monocyte-derived macrophages produce neurotoxic levels of L-cysteine Academic Article
- Deletion mutants of human interleukin 1β with significantly reduced agonist properties: Search for the agonist/antagonist switch in ligands to the interleukin 1 receptors Academic Article
- Delineation of the proinflammatory cytokine cascade in fever induction Academic Article
- Dentin conditioning codetermines cell fate in regenerative endodontics Academic Article
- Different cell-surface receptor determinants of antigenically similar influenza-virus hemagglutinins Academic Article
- Donor variation in the growth properties and osteogenic potential of human marrow stromal cells Academic Article
- Dual transduction of insulin-like growth factor-l and interleukin-1 receptor antagonist protein controls cartilage degradation in an osteoarthritic culture model Academic Article
- Effective replication of human influenza viruses in mice lacking a major alpha 2,6 sialyltransferase Academic Article
- Effects of chronic overexpression of interleukin-1 receptor antagonist in a model of permanent focal cerebral ischemia in mouse Academic Article
- Efficient bone formation by gene transfer of human LIM mineralization protein-3 Academic Article
- Elevated skeletal osteopontin levels contribute to the hypophosphatasia phenotype in Akp2(-/-) mice Academic Article
- Enzymatic and chemical approaches for the synthesis of sialyl glycoconjugates Academic Article
- Erythrocyte receptors for mycoplasma-pneumoniae are sialylated oligosaccharides of ii antigen type Academic Article
- Gene combination transfer to block autoimmune damage in transplanted islets of Langerhans Academic Article
- Gene therapy for arthritis: principles and clinical practice Academic Article
- Gene therapy for osteoporosis: Evaluation in a murine ovariectomy model Academic Article
- Gene transfer to human joints: progress toward a gene therapy of arthritis Academic Article
- Gene-mediated restoration of cartilage matrix by combination insulin-like growth factor-l/interleukin-1 receptor antagonist therapy Academic Article
- IL-1Ra and vIL-10 gene transfer using retroviral vectors ameliorates particle-associated inflammation in the murine air pouch model Academic Article
- Identification of osteopontin as a novel ligand for the integrin alpha 8 beta 1 and potential roles for this integrin-ligand interaction in kidney morphogenesis Academic Article
- Improved recovery and delayed cytokine induction after closed head injury in mice with central overexpression of the secreted isoform of the interleukin-1 receptor antagonist Academic Article
- In vitro transduction of human osteoblast cell population with retroviral vectors Academic Article
- In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapy Academic Article
- Infection of intact human islets by a lentiviral vector Academic Article
- Inhibition of cartilage destruction by double gene transfer of IL-1Ra and IL-10 involves the activin pathway Academic Article
- Inorganic pyrophosphate (PPI) in pathologic calcification of articular cartilage Academic Article
- Interleukin-1 beta enhances NMDA receptor-mediated intracellular calcium increase through activation of the Src family of kinases Academic Article
- Interleukin-1 receptor antagonist ameliorates experimental antiglomerular basement-membrane antibody-associated glomerulonephritis Academic Article
- Interleukin-1 receptor antagonist protein and mRNA in the rat adrenal gland Academic Article
- Intra-articular delivery of a herpes simplex virus il-1ra gene vector reduces inflammation in a rabbit model of arthritis Academic Article
- Intraarticular expression of biologically-active interleukin-1 receptor-antagonist protein by ex-vivo gene-transfer Academic Article
- Limited functional diversity in kappa-light-chains - junctional sequences from CD43(+)B220(+) early B-cell progenitors resemble those from peripheral B-cells Academic Article
- Linked deficiencies in extracellular PP(i) and osteopontin mediate pathologic calcification associated with defective PC-1 and ANK expression Academic Article
- Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects Academic Article
- Molecular topography of the neural cell-adhesion molecule n-cam - surface orientation and location of sialic acid-rich and binding regions Academic Article
- Osteoarthritis gene therapy Academic Article
- Powerful anticonvulsant action of IL-1 receptor antagonist on intracerebral injection and astrocytic overexpression in mice Academic Article
- Prolonged systemic expression of human IL-1 receptor antagonist (hIL-1ra) in mice reconstituted with hematopoietic-cells transduced with a retrovirus carrying the hIL-1ra cDNA Academic Article
- Protective effects of IL-1Ra or vIL-10 gene transfer on a murine model of wear debris-induced osteolysis Academic Article
- Receptor editing in a transgenic mouse model: Site, efficiency, and role in b cell tolerance and antibody diversification Academic Article
- Retroviral vectors for use in human gene-therapy for cancer Gaucher disease, and arthritis Academic Article
- Retrovirus-mediated gene transfer in lungs of living fetal sheep Academic Article
- Suppression of antigen-induced arthritis in rabbits by ex vivo gene therapy Academic Article
- Suppression of intraarticular responses to interleukin-1 by transfer of the interleukin-1 receptor antagonist gene to synovium Academic Article
- The interleukin-1 receptor antagonist and its delivery by gene-transfer Academic Article
- The synthesis and enzymatic incorporation of sialic acid derivatives for use as tools to study the structure, activity, and inhibition of glycoproteins and other glycoconjugates Academic Article
- Transfer of genes to chondrocytic cells of the lumbar spine. Proposal for a treatment strategy of spinal disorders by local gene therapy Academic Article
- Transgenic overexpression of interleukin-1 receptor antagonist in the CNS influences behaviour, serum corticosterone and brain monoamines Academic Article