subject area of
- A biometrical genome search in rats reveals the multigenic basis of blood-pressure variation Academic Article
- Activated protein C analog protects from ischemic stroke and extends the therapeutic window of tissue-type plasminogen activator in aged female mice and hypertensive rats Academic Article
- Blood-pressure in genetically hypertensive rats - influence of the y-chromosome Academic Article
- Cerebrospinal-fluid immunoreactive beta-endorphin concentration is increased by voluntary exercise in the spontaneously hypertensive rat Academic Article
- Common genetic mechanisms of blood pressure elevation in two independent rodent models of human essential hypertension Academic Article
- Design, synthesis, and biological evaluation of 3-[4-(2-hydroxyethyl)piperazin-1-yl]-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one, a potent, orally active, brain penetrant inhibitor of phosphodiesterase 5 (PDE5) Academic Article
- Genetic regulation of catecholamine synthesis, storage and secretion in the spontaneously hypertensive rat Academic Article
- Identification of quantitative trait loci for anxiety and locomotion phenotypes in rat recombinant inbred strains Academic Article
- Increased vasopressor actions of intraventricular neuropeptide y-(13-36) in spontaneously hypertensive versus normotensive wistar-kyoto rats - possible relationship to increases in y-2 receptor-binding in the nucleus-tractus-solitarius Academic Article
- Levels of dynorphin peptides in the central nervous system and pituitary gland of the spontaneously hypertensive rat Academic Article
- MicroRNA-22 and promoter motif polymorphisms at the Chga locus in genetic hypertension: functional and therapeutic implications for gene expression and the pathogenesis of hypertension Academic Article
- Optimization of the aminopyridopyrazinones class of PDE5 inhibitors: discovery of 3-[(trans-4-hydroxycyclohexyl)amino]-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one Academic Article
- Relationship of growth and blood-pressure in inbred rats Academic Article
- Telemetry for cardiovascular monitoring in a pharmacological study - new approaches to data analysis Academic Article