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Rats, Inbred SHR

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  • A biometrical genome search in rats reveals the multigenic basis of blood-pressure variation  Academic Article
  • Activated protein C analog protects from ischemic stroke and extends the therapeutic window of tissue-type plasminogen activator in aged female mice and hypertensive rats  Academic Article
  • Blood-pressure in genetically hypertensive rats - influence of the y-chromosome  Academic Article
  • Cerebrospinal-fluid immunoreactive beta-endorphin concentration is increased by voluntary exercise in the spontaneously hypertensive rat  Academic Article
  • Common genetic mechanisms of blood pressure elevation in two independent rodent models of human essential hypertension  Academic Article
  • Design, synthesis, and biological evaluation of 3-[4-(2-hydroxyethyl)piperazin-1-yl]-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one, a potent, orally active, brain penetrant inhibitor of phosphodiesterase 5 (PDE5)  Academic Article
  • Genetic regulation of catecholamine synthesis, storage and secretion in the spontaneously hypertensive rat  Academic Article
  • Identification of quantitative trait loci for anxiety and locomotion phenotypes in rat recombinant inbred strains  Academic Article
  • Increased vasopressor actions of intraventricular neuropeptide y-(13-36) in spontaneously hypertensive versus normotensive wistar-kyoto rats - possible relationship to increases in y-2 receptor-binding in the nucleus-tractus-solitarius  Academic Article
  • Levels of dynorphin peptides in the central nervous system and pituitary gland of the spontaneously hypertensive rat  Academic Article
  • MicroRNA-22 and promoter motif polymorphisms at the Chga locus in genetic hypertension: functional and therapeutic implications for gene expression and the pathogenesis of hypertension  Academic Article
  • Optimization of the aminopyridopyrazinones class of PDE5 inhibitors: discovery of 3-[(trans-4-hydroxycyclohexyl)amino]-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one  Academic Article
  • Relationship of growth and blood-pressure in inbred rats  Academic Article
  • Telemetry for cardiovascular monitoring in a pharmacological study - new approaches to data analysis  Academic Article

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