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Osteoarthritis

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  • 100 cemented versus 100 noncemented stems with comparison of 25 matched pairs  Academic Article
  • A stem cell-based approach to cartilage repair  Academic Article
  • Accelerated, aging-dependent development of osteoarthritis in alpha 1 integrin-deficient mice  Academic Article
  • Accuracy of CT-based measurements of glenoid version for total shoulder arthroplasty  Academic Article
  • Adenovirus-mediated gene transfer of insulin-like growth factor 1 stimulates proteoglycan synthesis in rabbit joints  Academic Article
  • Aging-related differences in chondrocyte viscoelastic properties  Academic Article
  • Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis  Academic Article
  • Atomic force microscopy reveals age-dependent changes in nanomechanical properties of the extracellular matrix of native human menisci: implications for joint degeneration and osteoarthritis  Academic Article
  • Autophagy activation by rapamycin reduces severity of experimental osteoarthritis  Academic Article
  • Autophagy and cartilage homeostasis mechanisms in joint health, aging and OA  Academic Article
  • Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis  Academic Article
  • Bach1 deficiency reduces severity of osteoarthritis through upregulation of heme oxygenase-1  Academic Article
  • Basic science of intra-articular fractures and posttraumatic osteoarthritis  Academic Article
  • Biomechanical regulation of matrix metalloproteinase-9 in cultured chondrocytes  Academic Article
  • Biomechanical, structural, and biochemical indices of degenerative and osteoarthritic deterioration of adult human articular cartilage of the femoral condyle  Academic Article
  • Both microRNA-455-5p and-3p repress hypoxia-inducible factor-2 alpha expression and coordinately regulate cartilage homeostasis  Academic Article
  • Cartilage cell clusters  Academic Article
  • Caspase inhibitors reduce severity of cartilage lesions in experimental osteoarthritis  Academic Article
  • Cell death in cartilage  Academic Article
  • Cellular and extracellular matrix changes in anterior cruciate ligaments during human knee aging and osteoarthritis  Academic Article
  • Characterization of selective exosite-binding inhibitors of matrix metalloproteinase 13 that prevent articular cartilage degradation in vitro  Academic Article
  • Chondrocyte AMP-activated protein kinase activity suppresses matrix degradation responses to proinflammatory cytokines interleukin-1 beta and tumor necrosis factor alpha  Academic Article
  • Chondrocyte apoptosis and nitric oxide production during experimentally induced osteoarthritis  Academic Article
  • Chondrocyte calcium-sensing receptor expression is up-regulated in early guinea pig knee osteoarthritis and modulates PTHrP, MMP-13, and TIMP-3 expression  Academic Article
  • Chondroprotective activity of N-acetylglucosamine in rabbits with experimental osteoarthritis  Academic Article
  • Development and regulation of osteophyte formation during experimental osteoarthritis  Academic Article
  • Development of comprehensive functional genomic screens to identify novel mediators of osteoarthritis  Academic Article
  • Differential metabolic effects of glucosamine and N-acetylglucosamine in human articular chondrocytes  Academic Article
  • Dual transduction of insulin-like growth factor-l and interleukin-1 receptor antagonist protein controls cartilage degradation in an osteoarthritic culture model  Academic Article
  • Evidence for the presence of receptors for c3 and igg fc on human synovial cells  Academic Article
  • Exosomes from IL-1β stimulated synovial fibroblasts induce osteoarthritic changes in articular chondrocytes  Academic Article
  • Expression of microRNA-146a in osteoarthritis cartilage  Academic Article
  • Expression of novel extracellular sulfatases Sulf-1 and Sulf-2 in normal and osteoarthritic articular cartilage  Academic Article
  • Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways  Academic Article
  • Fas/Fas ligand expression and induction of apoptosis in chondrocytes  Academic Article
  • Fibroblast activation protein alpha is expressed by chondrocytes following a pro-inflammatory stimulus and is elevated in osteoarthritis  Academic Article
  • Gene therapeutic approaches-transfer in vivo  Academic Article
  • Gene therapy for arthritis: principles and clinical practice  Academic Article
  • Gene therapy for the treatment of musculoskeletal diseases  Academic Article
  • Gene-mediated restoration of cartilage matrix by combination insulin-like growth factor-l/interleukin-1 receptor antagonist therapy  Academic Article
  • Getting arthritis gene therapy into the clinic  Academic Article
  • Halofuginone attenuates osteoarthritis by inhibition of TGF-β activity and H-type vessel formation in subchondral bone  Academic Article
  • Hexosaminidase inhibitors as new drug candidates for the therapy of osteoarthritis  Academic Article
  • Histopathological changes in the human posterior cruciate ligament during aging and osteoarthritis: Correlations with anterior cruciate ligament and cartilage changes  Academic Article
  • Identification and cross-species comparison of canine osteoarthritic gene regulatory cis-elements  Academic Article
  • In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapy  Academic Article
  • Inflammation-induced chondrocyte hypertrophy is driven by receptor for advanced glycation end products  Academic Article
  • Linkage of chondrocyte apoptosis and cartilage degradation in human osteoarthritis  Academic Article
  • Linked decreases in liver kinase B1 and AMP-activated protein kinase activity modulate matrix catabolic responses to biomechanical injury in chondrocytes  Academic Article
  • Macro view of microrna function in osteoarthritis  Academic Article
  • Mechanisms of chondrocyte apoptosis  Academic Article
  • Mesenchymal progenitor cell markers in human articular cartilage: normal distribution and changes in osteoarthritis  Academic Article
  • MicroRNA-140 plays dual roles in both cartilage development and homeostasis  Academic Article
  • Molecular network of cartilage homeostasis and osteoarthritis  Academic Article
  • Necessity of lysophosphatidic acid receptor 1 for development of arthritis  Academic Article
  • Nitric oxide in osteoarthritis  Academic Article
  • Nitric oxide production and apoptosis in cells of the meniscus during experimental osteoarthritis  Academic Article
  • Novel five-membered iminocyclitol derivatives as selective and potent glycosidase inhibitors: New structures for antivirals and osteoarthritis  Academic Article
  • Osteoarthritis gene therapy  Academic Article
  • Osteoarthritis year 2011 in review: Biology  Academic Article
  • Parathyroid hormone-related protein is abundant in osteoarthritic cartilage, and the parathyroid hormone-related protein 1-173 isoform is selectively induced by transforming growth factor beta in articular chondrocytes and suppresses generation of extracellular inorganic pyrophosphate  Academic Article
  • Peroxisome proliferator-activated receptor γ coactivator 1α and FoxO3A mediate chondroprotection by AMP-activated protein kinase  Academic Article
  • Posterior augmented glenoid designs preserve more bone in biconcave glenoids  Academic Article
  • Posttraumatic osteoarthritis: Pathogenesis and pharmacological treatment options  Academic Article
  • Potential treatment of osteoarthritis by gene therapy  Academic Article
  • Production of the chemokine RANTES by articular chondrocytes and role in cartilage degradation  Academic Article
  • Profile of glycosaminoglycan-degrading glycosidases and glycoside sulfatases secreted by human articular chondrocytes in homeostasis and inflammation  Academic Article
  • Rho kinase-dependent CCL20 induced by dynamic compression of human chondrocytes  Academic Article
  • Role of nitric oxide, reactive oxygen species, and p38 MAP kinase in the regulation of human chondrocyte apoptosis  Academic Article
  • Synthesis and high-throughput screening of N-acetyl-β-hexosaminidase inhibitor libraries targeting osteoarthritis  Academic Article
  • The marshall r. Urist young investigator award. Orthopaedic applications of gene therapy. From concept to clinic  Academic Article
  • The osteoprotegerin/receptor activator of nuclear factor kappa B/receptor activator of nuclear factor kappa B ligand system in cartilage  Academic Article
  • The relationship of autophagy defects to cartilage damage during joint aging in a mouse model  Academic Article
  • Treatment of experimental equine osteoarthritis by in vivo delivery of the equine interleukin-1 receptor antagonist gene  Academic Article
  • Value of biomarkers in osteoarthritis: current status and perspectives  Academic Article
  • Vimentin contributes to changes in chondrocyte stiffness in osteoarthritis  Academic Article

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