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Mice, Inbred C57BL

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  • 1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) analogs of CC-1065 and the duocarmycins: synthesis and evaluation  Academic Article
  • 1,3,8-Triazaspiro[4.5]decane-2,4-diones as efficacious pan-inhibitors of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) for the treatment of anemia  Academic Article
  • 11-deoxy prostaglandin F(2 alpha), a thromboxane A2 receptor agonist, partially alleviates embryo crowding in Lpar3(-/-) females  Academic Article
  • 5-HT(1A) receptor mutant mice exhibit enhanced tonic, stress-induced and fluoxetine-induced serotonergic neurotransmission  Academic Article
  • 5-HT(7) receptor inhibition and inactivation induce antidepressantlike behavior and sleep pattern  Academic Article
  • 5-aminoimidazole-4-carboxyamide-ribonucleoside (AICAR)-stimulated hepatic expression of Cyp4a10, Cyp4a14, Cyp4a31, and other peroxisome proliferator-activated receptor alpha-responsive mouse genes is AICAR 5'-monophosphate-dependent and AMP-activated protein kinase-independent  Academic Article
  • A 3-dimensional extracellular matrix as a delivery system for the transplantation of glioma-targeting neural stem/progenitor cells  Academic Article
  • A 5' leader of Rbm3, a cold stress-induced mRNA, mediates internal initiation of translation with increased efficiency under conditions of mild hypothermia  Academic Article
  • A DNA vaccine against vegf receptor 2 prevents effective angiogenesis and inhibits tumor growth  Academic Article
  • A DNA vaccine targeting fos-related antigen 1 enhanced by il-18 induces long-lived t-cell memory against tumor recurrence  Academic Article
  • A DNA vaccine targeting survivin combines apoptosis with suppression of angiogenesis in lung tumor eradication  Academic Article
  • A Jekyll and Hyde profile: Type 1 interferon signaling plays a prominent role in the initiation and maintenance of a persistent virus infection  Academic Article
  • A ZAP-70 kinase domain variant prevents thymocyte- positive selection despite signalling CD69 induction  Academic Article
  • A catalytically inactive mutant of the deubiquitylase YOD-1 enhances antigen cross-presentation  Academic Article
  • A catechol-O-methyltransferase that is essential for auditory function in mice and humans  Academic Article
  • A chemically induced vaccine strategy for prostate cancer  Academic Article
  • A chimeric mouse model of Gaucher disease  Academic Article
  • A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol  Academic Article
  • A crucial role of mitochondrial Hsp40 in preventing dilated cardiomyopathy  Academic Article
  • A derivative of the melanocortin receptor antagonist shu9119 (pg932) increases food intake when administered peripherally  Academic Article
  • A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid use  Academic Article
  • A dominant-negative mutant of c-Jun inhibits cell cycle progression during the transition of CD4(-)CD8(-) to CD4(+) CD8(+) thymocytes  Academic Article
  • A dual role for microglia in promoting tissue inhibitor of metalloproteinase (timp) expression in glial cells in response to neuroinflammatory stimuli  Academic Article
  • A factor IX-deficient mouse model for hemophilia B gene therapy  Academic Article
  • A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function  Academic Article
  • A functional genomics strategy reveals Rora as a component of the mammalian circadian clock  Academic Article
  • A genetic determinant that specifically regulates the frequency of hematopoietic stem cells  Academic Article
  • A genetically encoded multifunctional TRAIL trimer facilitates cell-specific targeting and tumor cell killing  Academic Article
  • A gfp-equipped bidirectional expression module well suited for monitoring tetracycline-regulated gene expression in mouse  Academic Article
  • A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity  Academic Article
  • A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia  Academic Article
  • A keratinocyte-responsive gamma delta tcr is necessary for dendritic epidermal t cell activation by damaged keratinocytes and maintenance in the epidermis  Academic Article
  • A lack of mu-opioid receptors modulates the expressions of neuropeptide y and substance p mrna  Academic Article
  • A leukocyte homologue of the il-8 receptor cxcr-2 mediates the accumulation of macrophages in atherosclerotic lesions of ldl receptor-deficient mice  Academic Article
  • A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses  Academic Article
  • A major histocompatibility complex class I-dependent subset of memory phenotype CD8(+) cells  Academic Article
  • A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration  Academic Article
  • A mouse model of pemphigus vulgaris by adoptive transfer of naive splenocytes from desmoglein 3 knockout mice  Academic Article
  • A multivalent minigene vaccine, containing b-cell, cytotoxic t-lymphocyte, and t-h epitopes from several microbes, induces appropriate responses in vivo and confers protection against more than one pathogen  Academic Article
  • A mutant mouse with a highly specific contextual fear-conditioning deficit found in an N-ethyl-N-nitrosourea (ENU) mutagenesis screen  Academic Article
  • A new UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase mRNA exhibits predominant expression in the hypothalamus, thalamus and amygdala of mouse forebrain  Academic Article
  • A novel DNA vaccine encoding pdgfr beta suppresses growth and dissemination of murine colon, lung and breast carcinoma  Academic Article
  • A novel ELISA for mouse activated protein C in plasma  Academic Article
  • A novel allele of myosin viia reveals a critical function for the c-terminal ferm domain for melanosome transport in retinal pigment epithelial cells  Academic Article
  • A novel and simple method for culturing pericytes from mouse brain  Academic Article
  • A novel approach for in vivo measurement of mouse red cell redox status  Academic Article
  • A novel class II MHC molecule with unusual tissue distribution  Academic Article
  • A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol with potential anti-obesity effects  Academic Article
  • A novel function of p38-regulated/activated kinase in endothelial cell migration and tumor angiogenesis  Academic Article
  • A novel generation of heparan sulfate mimetics for the treatment of prion diseases  Academic Article
  • A novel method for analysis of nuclear receptor function at natural promoters: Peroxisome proliferator-activated receptor gamma agonist actions on ap2 gene expression detected using branched DNA messenger rna quantitation  Academic Article
  • A novel method to establish microglia-free astrocyte cultures: Comparison of matrix metalloproteinase expression profiles in pure cultures of astrocytes and microglia  Academic Article
  • A novel neuron-specific DNA end-binding factor in the murine brain  Academic Article
  • A novel non-transcriptional pathway mediates the proconvulsive effects of interleukin-1β  Academic Article
  • A novel transgenic mouse model for immunological evaluation of carcinoembryonic antigen-based DNA minigene vaccines  Academic Article
  • A novel, systemically active, selective galanin receptor type-3 ligand exhibits antidepressant-like activity in preclinical tests  Academic Article
  • A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects  Academic Article
  • A pathologic cascade leading to synaptic dysfunction in alpha-synuclein-induced neurodegeneration  Academic Article
  • A peptide that antagonizes tcr-mediated reactions with both syngeneic and allogeneic agonists: Functional and structural aspects  Academic Article
  • A peptidomics strategy to elucidate the proteolytic pathways that inactivate peptide hormones  Academic Article
  • A phenotype survey of 36 mutant mouse strains with gene-targeted defects in glycosyltransferases or glycan-binding proteins  Academic Article
  • A photo-cleavable biotin affinity tag for the facile release of a photo-crosslinked carbohydrate-binding protein  Academic Article
  • A pivotal role for the multifunctional calcium/calmodulin-dependent protein kinase ii in t cells: From activation to unresponsiveness  Academic Article
  • A point mutation in sec61 alpha 1 leads to diabetes and hepatosteatosis in mice  Academic Article
  • A point mutation in the amino terminus of TLR7 abolishes signaling without affecting ligand binding  Academic Article
  • A population of murine gamma delta T cells that recognize an inducible MHC class Ib molecule  Academic Article
  • A possible oligosaccharide-conjugate vaccine candidate for Clostridium difficile is antigenic and immunogenic  Academic Article
  • A potential role for adiponectin receptor 2 (AdipoR2) in the regulation of alcohol intake  Academic Article
  • A ppar gamma-lxr-abca1 pathway in macrophages is involved in cholesterol efflux and atherogenesis  Academic Article
  • A proapoptotic peptide for the treatment of solid tumors  Academic Article
  • A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions  Academic Article
  • A rabbit antiserum detects a vh j558 subgroup marker highly expressed among anti-alprenolol antibodies  Academic Article
  • A regenerative approach to the treatment of multiple sclerosis  Academic Article
  • A reversible S-adenosyl-L-homocysteine hydrolase inhibitor ameliorates experimental autoimmune encephalomyelitis by inhibiting T cell activation  Academic Article
  • A role for dual viral hits in causation of subacute sclerosing panencephalitis  Academic Article
  • A role for skin γδ T cells in wound repair  Academic Article
  • A role for tcr affinity in regulating naive t cell homeostasis  Academic Article
  • A role for the GIRK3 subunit in methamphetamine-induced aAttenuation of GABA(B) receptor-activated GIRK currents in VTA dopamine neurons  Academic Article
  • A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition  Academic Article
  • A role of the fast ATP-gated P2X(1) cation channel in thrombosis of small arteries in vivo  Academic Article
  • A secreted Slit2 fragment regulates adipose tissue thermogenesis and metabolic function  Academic Article
  • A semisynthetic carbohydrate-lipid vaccine that protects against S-pneumoniae in mice  Academic Article
  • A shared neural ensemble links distinct contextual memories encoded close in time  Academic Article
  • A spontaneous rheumatoid arthritis-like disease in mrl/1 mice  Academic Article
  • A spontaneously arising pancreatic tumor does not promote the differentiation of naive CD8+ T lymphocytes into effector CTL  Academic Article
  • A stress response pathway regulates DNA damage through beta(2)-adrenoreceptors and beta-arrestin-1  Academic Article
  • A string-of-beads vaccine, comprising linked minigenes, confers protection from lethal-dose virus challenge  Academic Article
  • A structural hierarchy mediated by multiple nuclear factors establishes IgH locus conformation  Academic Article
  • A study of complexes of class II invariant chain peptide: major histocompatibility complex class II molecules using a new complex-specific monoclonal antibody  Academic Article
  • A substrate-free activity-based protein profiling screen for the discovery of selective PREPL inhibitors  Academic Article
  • A t-cell receptor-v-alpha region selectively expressed in cd4+ cells  Academic Article
  • A toll-like receptor 2-responsive lipid effector pathway protects mammals against skin infections with gram-positive bacteria  Academic Article
  • A transgenic mouse model for measles virus infection of the brain  Academic Article
  • A transgenic mouse model of the chronic hepatitis B surface antigen carrier state  Academic Article
  • A transgenic mouse model to assess the interaction of cytotoxic t-lymphocytes with virally infected, class-i mhc-expressing astrocytes  Academic Article
  • A v(h)11v(kappa)9b cell antigen receptor drives generation of cd5(+) b cells both in vivo and in vitro  Academic Article
  • A view from above: Cloud plots to visualize global metabolomic data  Academic Article
  • A viral epitope that mimics a self antigen can accelerate but nit initiate autoimmune diabetes  Academic Article
  • ABHD12 controls brain lysophosphatidylserine pathways that are deregulated in a murine model of the neurodegenerative disease PHARC  Academic Article
  • ABIN-1 protects against psoriasis by restricting MyD88 signals in dendritic cells  Academic Article
  • AMPAR-independent effect of striatal αCaMKII promotes the sensitization of cocaine reward  Academic Article
  • ASPP2 deficiency causes features of 1q41q42 microdeletion syndrome  Academic Article
  • ATP induces protein arginine deiminase 2-dependent citrullination in mast cells through the P2X7 purinergic receptor  Academic Article
  • ATP-sensitive potassium channel (K-ATP)-dependent regulation of cardiotropic viral infections  Academic Article
  • Aberrant development of the suprachiasmatic nucleus and circadian rhythms in mice lacking the homeodomain protein Six6  Academic Article
  • Ablation of NG2 proteoglycan leads to deficits in brown fat function and to adult onset obesity  Academic Article
  • Ablation of cd22 in ligand-deficient mice restores b cell receptor signaling  Academic Article
  • Ablation of ghrelin improves the diabetic but not obese phenotype of ob/ob mice  Academic Article
  • Abnormalities of plasma cytokines and spleen in senile APP/PS1/Tau transgenic mouse model  Academic Article
  • Absence of CTL responses to early viral antigens facilitates viral persistence  Academic Article
  • Absence of LPA1 signaling results in defective cortical development  Academic Article
  • Absence of carbohydrate response element binding protein in adipocytes causes systemic insulin resistance and impairs glucose transport  Academic Article
  • Absence of the alpha v beta 3 integrin dictates the time-course of angiogenesis in the hypoxic central nervous system: Accelerated endothelial proliferation correlates with compensatory increases in alpha 5 beta 1 integrin expression  Academic Article
  • Absence of the lysophosphatidic acid receptor LPA1 results in abnormal bone development and decreased bone mass  Academic Article
  • Activated intrahepatic antigen-presenting cells inhibit hepatitis B virus replication in the liver of transgenic mice  Academic Article
  • Activated protein C analog promotes neurogenesis and improves neurological outcome after focal ischemic stroke in mice via protease activated receptor 1  Academic Article
  • Activated protein C preserves functional islet mass after intraportal transplantation - a novel link between endothelial cell activation, thrombosis, inflammation, and islet cell death  Academic Article
  • Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3  Academic Article
  • Activated protein C promotes neovascularization and neurogenesis in postischemic brain via protease-activated receptor 1  Academic Article
  • Activated protein C targets CD8(+) dendritic cells to reduce the mortality of endotoxemia in mice  Academic Article
  • Activation kinetics and off-target effects of thymus-initiated cre transgenes  Academic Article
  • Activation of PPARdelta alters lipid metabolism in db/db mice  Academic Article
  • Activation of liver x receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue  Academic Article
  • Activation of lysophosphatidic acid receptor type 1 contributes to pathophysiology of spinal cord injury  Academic Article
  • Activation of multidrug resistance (P-glycoprotein) mdr3/mdr1a gene during the development of hepatocellular carcinoma in hepatitis B virus transgenic mice  Academic Article
  • Activation of murine cd4(+) and cd8(+) t lymphocytes leads to dramatic remodeling of n-linked glycans  Academic Article
  • Activation of preexisting t cell clones by targeted interleukin 2 therapy  Academic Article
  • Activation of the alpha7 nAChR reduces acid-induced acute lung injury in mice and rats  Academic Article
  • Activation of the alternative complement pathway by fetal calf serum and mouse thymocytes  Academic Article
  • Activation of the endocannabinoid system by organophosphorus nerve agents  Academic Article
  • Activation/division of lymphocytes results in increased levels of cytoplasmic activation/proliferation-associated protein-1: prototype of a new family of proteins  Academic Article
  • Activators of the nuclear receptor ppar gamma enhance colon polyp formation  Academic Article
  • Acute exposure to cxc chemokine ligand 10, but not its chronic astroglial production, alters synaptic plasticity in mouse hippocampal slices  Academic Article
  • Acylated and unacylated ghrelin impair skeletal muscle atrophy in mice  Academic Article
  • Adaptation of the bovine spongiform encephalopathy agent to primates and comparison with Creutzfeldt-- Jakob disease: implications for human health  Academic Article
  • Adenoviral delivery of CTLA4ig into myeloid dendritic cells promotes their in vitro tolerogenicity and survival in allogeneic recipients  Academic Article
  • Adenoviral-mediated, intratumor gene transfer of interleukin 23 induces a therapeutic antitumor response  Academic Article
  • Adenovirus serotype 5 fiber shaft influences in vivo gene transfer in mice  Academic Article
  • Adenovirus-mediated direct gene therapy with bone morphogenetic protein-2 produces bone  Academic Article
  • AdipoR1 and 2 are expressed on warm sensitive neurons of the hypothalamic preoptic area and contribute to central hyperthermic effects of adiponectin  Academic Article
  • Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARγ specifies lipid storage versus thermogenic gene programs  Academic Article
  • Adjuvant activity of the histamine-sensitizing factor of Bordetella pertussis in different strains of mice  Academic Article
  • Adjuvant therapy with agonistic antibodies to CD134 (OX40) increases local control after surgical or radiation therapy of cancer in mice  Academic Article
  • Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling  Academic Article
  • Administration of systemic or local interleukin-2 enhances the antitumor effects of interleukin-12 gene-therapy  Academic Article
  • Adoptive immunotherapy induces cns dendritic cell recruitment and antigen presentation during clearance of a persistent viral infection  Academic Article
  • Adoptive transfer of fluorescence-labeled cells shows that resident peritoneal-macrophages are able to migrate into specialized lymphoid organs and inflammatory sites in the mouse  Academic Article
  • Adropin deficiency is associated with increased adiposity and insulin resistance  Academic Article
  • Adult mice generated from induced pluripotent stem cells  Academic Article
  • Afamin secreted from nonresorbing osteoclasts acts as a chemokine for preosteoblasts via the Akt-signaling pathway  Academic Article
  • Age- and gender-specific changes of hypocretin immunopositive neurons in C57Bl/6 mice  Academic Article
  • Age-dependent loss of sperm production in mice via impaired tysophosphatidic acid signaling  Academic Article
  • Age-related effects of Ginkgo biloba extract on synaptic plasticity and excitability  Academic Article
  • Aged app23 mice show a delay in switching to the use of a strategy in the barnes maze  Academic Article
  • Aging accelerates endotoxin-induced thrombosis: increased responses of plasminogen activator inhibitor-1 and lipopolysaccharide signaling with aging  Academic Article
  • Aging leads to a programmed loss of brown adipocytes in murine subcutaneous white adipose tissue  Academic Article
  • Aging leads to disturbed homeostasis of memory phenotype cd8(+) cells  Academic Article
  • Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics  Academic Article
  • Allelic exclusion of mouse t-cell receptor-alpha chains occurs at the time of thymocyte tcr up-regulation  Academic Article
  • Allelic exclusion of the tcr alpha-chain is an active process requiring tcr-mediated signaling and c-cbl  Academic Article
  • Alloantibodies can discriminate class I major histocompatibility complex molecules associated with various endogenous peptides  Academic Article
  • Alloantigen-enhanced accumulation of CCR5+ 'effector' regulatory T cells in the gravid uterus  Academic Article
  • Allosteric activators of glucokinase: potential role in diabetes therapy  Academic Article
  • Alpha 8 integrin in glomerular mesangial cells and in experimental glomerulonephritis  Academic Article
  • Alterations in neural cell-adhesion molecules during development of different regions of the nervous-system  Academic Article
  • Alterations of endocannabinoid signaling, synaptic plasticity, learning, and memory in monoacylglycerol lipase knock-out mice  Academic Article
  • Altered activity-rest patterns in mice with a human autosomal-dominant nocturnal frontal lobe epilepsy mutation in the β2 nicotinic receptor  Academic Article
  • Altered central nervous system gene expression caused by congenitally acquired persistent infection with lymphocytic choriomeningitis virus  Academic Article
  • Altered functional and biochemical response by CD8+ T cells that remain after tolerance  Academic Article
  • Altered helper T lymphocyte function associated with chronic hepatitis B virus infection and its role in response to therapeutic vaccination in humans  Academic Article
  • Altered synaptic transmission in the hippocampus of transgenic mice with enhanced central nervous systems expression of interleukin-6  Academic Article
  • Alternative mRNA splicing produces a novel biologically active short isoform of PGC-1 alpha  Academic Article
  • Alternatively spliced tissue factor induces angiogenesis through integrin ligation  Academic Article
  • Amelioration of chronic murine colitis by peptide-mediated transduction of the I kappa B kinase inhibitor NEMO binding domain peptide  Academic Article
  • Amisulpride is a potent 5-ht(7) antagonist: Relevance for antidepressant actions in vivo  Academic Article
  • Among cxcr3 chemokines, ifn-gamma-inducible protein of 10 kda (cxc chemokine ligand (cxcl) 10) but not monokine induced by ifn-gamma (cxcl9) imprints a pattern for the subsequent development of autoimmune disease  Academic Article
  • Amphotericin B increases influenza A virus infection by preventing IFITM3-mediated restriction  Academic Article
  • Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD  Academic Article
  • Amyloid and nonfibrillar deposits in mice transgenic for wild-type human transthyretin: A possible model for senile systemic amyloidosis  Academic Article
  • Amyloid deposition in the hippocampus and entorhinal cortex: Quantitative analysis of a transgenic mouse model  Academic Article
  • An IRF-3-, IRF-5-, and IRF-7-independent pathway of dengue viral resistance utilizes IRF-1 to stimulate type I and II interferon responses  Academic Article
  • An activated protein c analog with reduced anticoagulant activity extends the therapeutic window of tissue plasminogen activator for ischemic stroke in rodents  Academic Article
  • An active dominant mutation of glycyl-tRNA synthetase causes neuropathy in a Charcot-Marie-Tooth 2D mouse model  Academic Article
  • An activity-based imaging probe for the integral membrane hydrolase KIAA1363  Academic Article
  • An ahemolytic pneumolysin of Streptococcus pneumoniae manipulates human innate and CD4⁺ T-cell responses and reduces resistance to colonization in mice in a serotype-independent manner  Academic Article
  • An analog of the natural steroidal alkaloid cortistatin A potently suppresses Tat-dependent HIV transcription  Academic Article
  • An angiogenic role for the alpha 5 beta 1 integrin in promoting endothelial cell proliferation during cerebral hypoxia  Academic Article
  • An anti-apoptotic peptide improves survival in lethal total body irradiation  Academic Article
  • An antibody-interleukin 2 fusion protein overcomes tumor heterogeneity by induction of a cellular immune response  Academic Article
  • An apolipoprotein e synthetic peptide targets to lipoproteins in plasma and mediates both cellular lipoprotein interactions in vitro and acute clearance of cholesterol-rich lipoproteins in vivo  Academic Article
  • An autologous oral DNA vaccine protects against murine melanoma  Academic Article
  • An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. II. Mammalian fibroblast cultures transformed by DNA and RNA tumor viruses  Academic Article
  • An essential role for Rxr alpha in the development of Th2 responses  Academic Article
  • An oral DNA vaccine against human carcinoembryonic antigen (cea) prevents growth and dissemination of lewis lung carcinoma in cea transgenic mice  Academic Article
  • Analysis of antigen-specific B-cell memory directly ex vivo  Academic Article
  • Analysis of central b cell tolerance in autoimmune-prone mrl/lpr mice bearing autoantibody transgenes  Academic Article
  • Analysis of individual immunoglobulin-lambda light-chain genes amplified from single cells is inconsistent with variable region gene conversion in germinal-center b-cell somatic mutation  Academic Article
  • Analysis of sphingosine 1-phosphate receptors involved in constriction of isolated cerebral arteries with receptor null mice and pharmacological tools  Academic Article
  • Analysis of the MCMV resistome by ENU mutagenesis  Academic Article
  • Analysis of the effect of estrogen/androgen perturbation on penile development in transgenic and diethylstilbestrol-Treated mice  Academic Article
  • Analysis of the proteolysis of bioactive peptides using a peptidomics approach  Academic Article
  • Analysis of the therapeutic functions of novel melanocortin receptor agonists in mc3r-and mc4r-deficient c57bl/6j mice  Academic Article
  • Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum  Academic Article
  • Anandamide-induced neuroblastoma cell rounding via the CB1 cannabinoid receptors  Academic Article
  • Anchorless prion protein results in infectious amyloid disease without clinical scrapie  Academic Article
  • Aneuploid cells are differentially susceptible to caspase-mediated death during embryonic cerebral cortical development  Academic Article
  • Angiomotin regulates endothelial cell migration during embryonic angiogenesis  Academic Article
  • Animal model of respiratory syncytial virus: CD8(+) T cells cause a cytokine storm that is chemically tractable by sphingosine-1-phosphate 1 receptor agonist therapy  Academic Article
  • Antagonism between MyD88- and TRIF-dependent signals in B7RP-1 up-regulation  Academic Article
  • Antagonizing peroxisome proliferator-activated receptor α activity selectively enhances Th1 immunity in male mice  Academic Article
  • Anti-Gag cytolytic T lymphocytes specific for an alternative translational reading frame-derived epitope and resistance versus susceptibility to retrovirus-induced murine AIDS in F(1) mice  Academic Article
  • Anti-IFN-alpha/beta receptor antibody treatment ameliorates disease in lupus-predisposed mice  Academic Article
  • Anti-OX40 stimulation in vivo enhances CD8(+) memory T cell survival and significantly increases recall responses  Academic Article
  • Anti-apoptotic peptides protect against radiation-induced cell death  Academic Article
  • Anti-cd11b antibody prevents immunopathologic changes in viable moth-eaten bone-marrow chimeric mice  Academic Article
  • Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones  Academic Article
  • Anti-inflammatory, antithrombotic, and neuroprotective effects of activated protein C in a murine model of focal ischemic stroke  Academic Article
  • Antibacterial effect of human mesenchymal stem cells is mediated in part from secretion of the antimicrobial peptide LL-37  Academic Article
  • Antibiotic-induced microbiome depletion alters metabolic homeostasis by affecting gut signaling and colonic metabolism  Academic Article
  • Anticonvulsant activity of a nonpeptide galanin receptor agonist  Academic Article
  • Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation  Academic Article
  • Antidiabetic activity of a highly potent and selective nonpeptide somatostatin receptor subtype-2 agonist  Academic Article
  • Antigen delivery to macrophages using liposomal nanoparticles targeting sialoadhesin/cd169  Academic Article
  • Antigen presentation in retroviral vector-mediated gene transfer in vivo  Academic Article
  • Antigen-driven B cell differentiation in vivo  Academic Article
  • Antigen-induced unresponsiveness results in altered t cell signaling  Academic Article
  • Antigen-specific b cell memory: Expression and replenishment of a novel b220(-) memory b cell compartment  Academic Article
  • Antigen-specific cytotoxicity by invariant NKT cells in vivo is CD95/CD178-dependent and is correlated with antigenic potency  Academic Article
  • Antigen-specific naive CD8(+) T cells produce a single pulse of IFN-gamma in vivo within hours of infection, but without antiviral effect  Academic Article
  • Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis  Academic Article
  • Antioxidant or neurotrophic factor treatment preserves function in a mouse model of neovascularization-associated oxidative stress  Academic Article
  • Antiphospholipid antibodies are directed against epitopes of oxidized phospholipids - recognition of cardiolipin by monoclonal antibodies to epitopes of oxidized low density lipoprotein  Academic Article
  • Antiplatelet drug therapy moderates immune-mediated liver disease and inhibits viral clearance in mice infected with a replication-deficient adenovirus  Academic Article
  • Antiproliferation activity of a small molecule repressor of liver receptor homolog 1  Academic Article
  • Antipsychotic drug treatment alters expression of mrnas encoding lipid metabolism-related proteins  Academic Article
  • Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models  Academic Article
  • Anxiolytic-Like Effects of Antisauvagine-30 in Mice Are Not Mediated by CRF2 Receptors  Academic Article
  • ApoE4 decreases spine density and dendritic complexity in cortical neurons in vivo  Academic Article
  • Apoa1 reduces free cholesterol accumulation in atherosclerotic lesions of apoe-deficient mice transplanted with apoe-expressing macrophages  Academic Article
  • Architecture of cannabinoid signaling in mouse retina  Academic Article
  • Area specificity and topography of thalamocortical projections are controlled by ephrin/eph genes  Academic Article
  • Arenavirus genome rearrangement for the development of live attenuated vaccines  Academic Article
  • Arginine 54 and tyrosine 118 residues of αA-crystallin are crucial for lens formation and transparency  Academic Article
  • Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction  Academic Article
  • Arylsulfonamide kcn1 inhibits in vivo glioma growth and interferes with hif signaling by disrupting hif-1 alpha interaction with cofactors p300/cbp  Academic Article
  • Ascl1 defines sequentially generated lineage-restricted neuronal and oligodendrocyte precursor cells in the spinal cord  Academic Article
  • Assessing interactions between Ghsr and Mc3r reveals a role for AgRP in the expression of food anticipatory activity in male mice  Academic Article
  • Assessment of anandamide's pharmacological effects in mice deficient of both fatty acid amide hydrolase and cannabinoid CB1 receptors  Academic Article
  • Association of cartilage-specific deletion of peroxisome proliferator-activated receptor gamma with abnormal endochondral ossification and impaired cartilage growth and development in a murine model  Academic Article
  • Astrocyte hypoxic response is essential for pathological but not developmental angiogenesis of the retina  Academic Article
  • Astrocyte pVHL and HIF-alpha isoforms are required for embryonic-to-adult vascular transition in the eye  Academic Article
  • Astrocytes are the primary source of tissue factor in the murine central nervous system. A role for astrocytes in cerebral hemostasis  Academic Article
  • Astrocytes contribute to gamma oscillations and recognition memory  Academic Article
  • Atg5-independent autophagy regulates mitochondrial clearance and is essential for iPSC reprogramming  Academic Article
  • Atheroprotective potential of macrophage-derived phospholipid transfer protein in low-density lipoprotein receptor-deficient mice is overcome by apolipoprotein ai overexpression  Academic Article
  • Atherosclerosis in mice is not affected by a reduction in tissue factor expression  Academic Article
  • Attenuation of allergic contact dermatitis through the endocannabinoid system  Academic Article
  • Attenuation of experimental autoimmune hepatitis by exogenous and endogenous cannabinoids: Involvement of regulatory T cells  Academic Article
  • Aurora kinases a and b are up-regulated by myc and are essential for maintenance of the malignant state  Academic Article
  • Autocrine selection of a GLP-1R G-protein biased agonist with potent antidiabetic effects  Academic Article
  • Autoimmunity-associated LYP-W620 does not impair thymic negative selection of autoreactive T cells  Academic Article
  • Autologous regulation of naive t cell homeostasis within the t cell compartment  Academic Article
  • Automatic annotation of matrix-assisted laser desorption/ionization n-glycan spectra  Academic Article
  • Autophagy activation by rapamycin reduces severity of experimental osteoarthritis  Academic Article
  • Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis  Academic Article
  • Autotaxin and lysophosphatidic acid(1) receptor-mediated demyelination of dorsal root fibers by sciatic nerve injury and intrathecal lysophosphatidylcholine  Academic Article
  • Avidity of cd1d-ligand-receptor ternary complex contributes to t-helper 1 (th1) polarization and anticancer efficacy  Academic Article
  • Azetidine and piperidine carbamates as efficient, covalent inhibitors of monoacylglycerol lipase  Academic Article
  • B cell selection defects underlie the development of diabetogenic apcs in nonobese diabetic mice  Academic Article
  • B cells from knock-in mice expressing broadly neutralizing HIV antibody b12 carry an innocuous B cell receptor responsive to HIV vaccine candidates  Academic Article
  • B-cell development in mice that lack one or both immunoglobulin kappa-light chain genes  Academic Article
  • B7 expression on thymic medullary epithelium correlates with epithelium-mediated deletion of v-beta-5(+) thymocytes  Academic Article
  • B7-1/2, but not PD-L1/2 molecules, are required on IL-10-treated tolerogenic DC and DC-derived exosomes for in vivo function  Academic Article
  • BCR engagement induces Fas resistance in primary B cells in the absence of functional Bruton's tyrosine kinase  Academic Article
  • BDNF overexpression in the forebrain rescues Huntington's disease phenotypes in YAC128 mice  Academic Article
  • BDNF promotes differentiation and maturation of adult-born neurons through GABAergic transmission  Academic Article
  • BK channel β1 subunit contributes to behavioral adaptations elicited by chronic intermittent ethanol exposure  Academic Article
  • Bacopaside I ameliorates cognitive impairment in APP/PS1 mice via immune-mediated clearance of β-amyloid.  Academic Article
  • Barx2 is expressed in satellite cells and is required for normal muscle growth and regeneration  Academic Article
  • Basomedial amygdala mediates top-down control of anxiety and fear  Academic Article
  • Bax loss impairs myc-induced apoptosis and circumvents the selection of p53 mutations during myc-mediated lymphomagenesis  Academic Article
  • Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis  Academic Article
  • Bcr ligation induces receptor editing in igm(+)igd(-) bone marrow b cells in vitro  Academic Article
  • Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex  Academic Article
  • Behavioral and neural correlates of acute and scheduled hunger in C57BL/6 mice  Academic Article
  • Behavioral and neurochemical studies on brain aging in galanin overexpressing mice  Academic Article
  • Behavioral phenotype of maLPA1-null mice: Increased anxiety-like behavior and spatial memory deficits  Academic Article
  • Beta 1-integrins are required for hippocampal AMPA receptor-dependent synaptic transmission, synaptic plasticity, and working memory  Academic Article
  • Beta 2-microglobulin is required for the full expression of xenobiotic-induced systemic autoimmunity  Academic Article
  • Beta 8 integrin and band 4.1b cooperatively regulate morphogenesis of the embryonic heart  Academic Article
  • Beyond the 12/23 rule of VDJ recombination independent of the Rag proteins  Academic Article
  • Bim siRNA decreases lymphocyte apoptosis and improves survival in sepsis  Academic Article
  • Binding of thymus- and bone marrow-derived lymphoid cells to antigen-derivatized fibers  Academic Article
  • Biogenic amine synthesis and uptake in rodent taste buds  Academic Article
  • Bioinformatic analysis of circadian gene oscillation in mouse aorta  Academic Article
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  • Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus. V. Recognition is restricted to gene products encoded by the viral S RNA segment  Academic Article
  • Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus. VI. Migration and activity in vivo in acute and persistent infection  Academic Article
  • Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus: clearance of virus in vivo  Academic Article
  • Biomagnetic isolation of antigen-specific CD8(+) T cells usable in immunotherapy  Academic Article
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  • Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain  Academic Article
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  • Bone marrow plasmacytoid dendritic cells can differentiate into myeloid dendritic cells upon virus infection  Academic Article
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  • Bone marrow-derived cells fail to induce positive selection in thymus reaggregation cultures  Academic Article
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  • Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor  Academic Article
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  • CD4+ T cells are required for development of a murine retrovirus-induced immunodeficiency syndrome (MAIDS)  Academic Article
  • CD4+ T cells pass through an effector phase during the process of in vivo tolerance induction  Academic Article
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  • CD8+ memory T cells appear exhausted within hours of acute virus infection  Academic Article
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  • Catecholamines in mutant mouse cerebellum - fluorescence microscopic and chemical studies  Academic Article
  • Cathepsin L acutely alters microvessel integrity within the neurovascular unit during focal cerebral ischemia  Academic Article
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  • Cd2-deficient mice generate virus-specific cytotoxic t-lymphocytes upon infection with lymphocytic choriomeningitis virus  Academic Article
  • Cd22 is a recycling receptor that can shuttle cargo between the cell surface and endosomal compartments of b cells  Academic Article
  • Cd22 regulates adaptive and innate immune responses of b cells  Academic Article
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  • Cd4 t cell control primary measles virus infection of the cns: Regulation is dependent on combined activity with either cd8 t cells or with b cells: Cd4, cd8 or b cells alone are ineffective  Academic Article
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  • Cd4-deficient mice have reduced levels of memory cytotoxic t lymphocytes after immunization and show diminished resistance to subsequent virus challenge  Academic Article
  • Cd40 ligand-mediated interactions are involved in the generation of memory cd8(+) cytotoxic t lymphocytes (ctl) but are not required for the maintenance of ctl memory following virus infection  Academic Article
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  • Cell surface 4-1bbl mediates sequential signaling pathways 'downstream' of tlr and is required for sustained tnf production in macrophages  Academic Article
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  • Ceramide mediates the rapid phase of febrile response to IL-1β  Academic Article
  • Changes in procoagulant and fibrinolytic gene expression during bleomycin-induced lung injury in the mouse  Academic Article
  • Changes in striatal signaling induce remodeling of RGS complexes containing G beta 5 and R7BP subunits  Academic Article
  • Characteristics of immunity induced by viral antigen or conferred by antibody via different administration routes  Academic Article
  • Characterization of GABA- and glycine-induced currents of solitary rodent retinal ganglion cells in culture  Academic Article
  • Characterization of TCR gene rearrangements during adult murine T cell development  Academic Article
  • Characterization of a class of cationic peptides able to facilitate efficient protein transduction in vitro and in vivo  Academic Article
  • Characterization of conditioned place preference to cocaine in congenic dopamine transporter knockout female mice  Academic Article
  • Characterization of kappa opioid receptor mediated, dynorphin-stimulated [(35)S]GTPγS binding in mouse striatum for the evaluation of selective KOR ligands in an endogenous setting  Academic Article
  • Characterization of mice lacking candidate N-acyl ethanolamine biosynthetic enzymes provides evidence for multiple pathways that contribute to endocannabinoid production in vivo  Academic Article
  • Characterization of mouse mutants with abnormal RPE cells  Academic Article
  • Characterization of the effects of reuptake and hydrolysis inhibition on interstitial endocannabinoid levels in the brain: an in vivo microdialysis study  Academic Article
  • Characterization of the murine antigenic determinant, designated l3t4a, recognized by monoclonal-antibody gk1.5 - expression of l3t4a by functional t-cell clones appears to correlate primarily with class ii mhc antigen-reactivity  Academic Article
  • Characterization of vascular adhesion molecules that may facilitate progenitor homing in the post-natal mouse thymus  Academic Article
  • Chemokine expression by intraepithelial gamma delta t cells - implications for the recruitment of inflammatory cells to damaged epithelia  Academic Article
  • Chemokine guidance of central memory T cells is critical for antiviral recall responses in lymph nodes  Academic Article
  • Chimeric molecules created by gene amplification interfere with the analysis of somatic hypermutation of murine immunoglobulin genes  Academic Article
  • Chmp5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis  Academic Article
  • Chondrogenesis mediated by PPi depletion promotes spontaneous aortic calcification in NPP1-/- mice  Academic Article
  • Chromosomal mapping of mouse genes expressed selectively within the central-nervous-system  Academic Article
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  • Chronic deprivation of TrkB signaling leads to selective late-onset nigrostriatal dopaminergic degeneration  Academic Article
  • Chronic haloperidol treatment results in a decrease in the expression of myelin/oligodendrocyte-related genes in the mouse brain  Academic Article
  • Chronic lymphocytic inflammation specifies the organ tropism of prions  Academic Article
  • Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system  Academic Article
  • Chronic morphine induces premature mitosis of proliferating cells in the adult mouse subgranular zone  Academic Article
  • Cipc is a mammalian circadian clock protein without invertebrate homologues  Academic Article
  • Circadian oscillations of protein-coding and regulatory RNAs in a highly dynamic mammalian liver epigenome  Academic Article
  • Circadian timing of ethanol exposure exerts enduring effects on subsequent ad libitum consumption in c57 mice  Academic Article
  • Circuitry for associative plasticity in the amygdala involves endocannabinoid signaling  Academic Article
  • Citrullination of proteins: A common post-translational modification pathway induced by different nanoparticles in vitro and in vivo  Academic Article
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  • Class-i mhc can present an endogenous peptide to cyto-toxic lymphocytes-t  Academic Article
  • Class-switched memory B cells remodel BCRs within secondary germinal centers  Academic Article
  • Click chemistry-facilitated comprehensive identification of proteins adducted by antimicrobial 5-nitroimidazoles for discovery of alternative drug targets against giardiasis  Academic Article
  • Clinical features of bacterial vaginosis in a murine model of vaginal infection with Gardnerella vaginalis  Academic Article
  • Clonal analysis of autoantibody-producing cell precursors in the preimmune b-cell repertoire  Academic Article
  • Clonal analysis of mechanisms of murine t-helper cell collaboration with effector-cells of macrophage lineage  Academic Article
  • Cloned cytotoxic T lymphocytes as target cells. II. Polarity of lysis revisited  Academic Article
  • Cloning and characterization of the genes encoding the ankyrin repeat and SOCS box-containing proteins Asb-1, Asb-2, Asb-3 and Asb-4  Academic Article
  • Cloning and sequencing of cDNA encoding mouse cytohesin-1  Academic Article
  • Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprotein e-deficient mice - demonstration of epitopes of oxidized low density lipoprotein in human plasma  Academic Article
  • Clozapine increases apolipoprotein d expression in rodent brain: Towards a mechanism for neuroleptic pharmacotherapy  Academic Article
  • Clozapine specifically alters the arachidonic acid pathway in mice lacking apolipoprotein d  Academic Article
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  • Combination OX40 agonism/CTLA-4 blockade with HER2 vaccination reverses T-cell anergy and promotes survival in tumor-bearing mice  Academic Article
  • Combination therapy targeting both tumor-initiating and differentiated cell populations in prostate carcinoma  Academic Article
  • Combined inhibition of FAAH and COX produces enhanced anti-allodynic effects in mouse neuropathic and inflammatory pain models  Academic Article
  • Combined targeting of costimulatory (OX40) and coinhibitory (CTLA-4) pathways elicits potent effector T cells capable of driving robust antitumor immunity  Academic Article
  • Commitment to the T-cell receptor-alpha-beta or receptor-gamma-delta lineages can occur just prior to the onset of CD4 and CD8 expression among immature thymocytes  Academic Article
  • Common antiviral cytotoxic t-lymphocyte epitope for diverse arenaviruses  Academic Article
  • Comparative analysis of antitumor activity of CD40L, RANKL, and 4-1BBL in vivo following intratumoral administration of viral vectors or transduced dendritic cells  Academic Article
  • Comparative analysis of dendritic cells transduced with different anti-apoptotic molecules: sensitivity to tumor-induced apoptosis  Academic Article
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  • Comparison of anandamide transport in FAAH wild-type and knockout neurons: Evidence for contributions by both FAAH and the CB1 receptor to anandamide uptake  Academic Article
  • Comparison of g-protein activation in the brain by mu-, delta-, and kappa-opioid receptor agonists in mu-opioid receptor knockout mice  Academic Article
  • Compensatory redistribution of neuroligins and N-cadherin following deletion of synaptic β1-integrin  Academic Article
  • Completion of the entire hepatitis C virus life cycle in genetically humanized mice  Academic Article
  • Conformational differences in major histocompatibility complex-peptide complexes can result in alloreactivity  Academic Article
  • Connections between connexins, calcium, and cataracts in the lens  Academic Article
  • Connexin 50 regulates surface ball-and-socket structures and fiber cell organization  Academic Article
  • Connexin mediated cataract prevention in mice  Academic Article
  • Consequences of cytotoxic T lymphocyte interaction with major histocompatibility complex class I-expressing neurons in vivo  Academic Article
  • Consequences of self-presentation of peptide antigen by cytolytic T lymphocytes  Academic Article
  • Conserved amino acid residues in the complementarity-determining region 1 of the TCR β-chain are involved in the recognition of conventional Ag and Mls-1 superantigen  Academic Article
  • Consolidation of learning strategies during spatial working memory task requires protein synthesis in the prefrontal cortex  Academic Article
  • Contribution of spinal 5-ht1a and 5-ht7 receptors to locomotor-like movement induced by 8-oh-dpat in spinal cord-transected mice  Academic Article
  • Contributions of neuronal prion protein on sleep recovery and stress response following sleep deprivation  Academic Article
  • Contributions of thrombin targets to tissue factor-dependent metastasis in hyperthrombotic mice  Academic Article
  • Control of memory formation through regulated expression of a camkii transgene  Academic Article
  • Control of spine maturation and pruning through proBDNF synthesized and released in dendrites  Academic Article
  • Convergence of itch-induced ubiquitination with MEKK1-JNK signaling in Th2 tolerance and airway inflammation  Academic Article
  • Converting IL-15 to a superagonist by binding to soluble IL-15R alpha  Academic Article
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  • Cooperative effects of aminopeptidase N (CD13) expressed by nonmalignant and cancer cells within the tumor microenvironment  Academic Article
  • Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis  Academic Article
  • Coordinated transcription of key pathways in the mouse by the circadian clock  Academic Article
  • Copresentation of antigen and ligands of Siglec-G induces B cell tolerance independent of CD22  Academic Article
  • Correction of RT-qPCR data for genomic DNA-derived signals with ValidPrime  Academic Article
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  • Corticotropin-releasing factor receptors CRF1 and CRF2 exert both additive and opposing influences on defensive startle behavior  Academic Article
  • Costimulation requirements of induced murine systemic autoimmune disease  Academic Article
  • Costimulatory molecule DNAM-1 is essential for optimal differentiation of memory natural killer cells during mouse cytomegalovirus infection  Academic Article
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  • Covalent linkage of HIV-1 trimers to synthetic liposomes elicits improved B cell and antibody responses  Academic Article
  • Coxsackievirus B3 infects the bone marrow and diminishes the restorative capacity of erythroid and lymphoid progenitors  Academic Article
  • Coxsackievirus b3 inhibits antigen presentation in vivo, exerting a profound and selective effect on the mhc class i pathway  Academic Article
  • Coxsackievirus b3-induced myocarditis - perforin exacerbates disease, but plays no detectable role in virus clearance  Academic Article
  • Coxsackievirus can exploit LC3 in both autophagy-dependent and -independent manners in vivo  Academic Article
  • Coxsackievirus infection induces autophagy-like vesicles and megaphagosomes in pancreatic acinar cells in vivo  Academic Article
  • Coxsackievirus infection of the pancreas: Evaluation of receptor expression, pathogenesis, and immunopathology  Academic Article
  • Coxsackievirus preferentially replicates and induces cytopathic effects in undifferentiated neural progenitor cells  Academic Article
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  • Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses  Academic Article
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  • Cross-linking cellular prion protein triggers neuronal apoptosis in vivo  Academic Article
  • Cross-reactivity between hl-a and h-2 antigens. Ii. Allogeneic sensitization by xenogeneic soluble lymphocyte antigens (hl-a)  Academic Article
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  • Crystal structure of an mhc class i presented glycopeptide that generates carbohydrate-specific ctl  Academic Article
  • Cta1-dd adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization  Academic Article
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  • Cutting edge: Early ifn-gamma signaling directly enhances primary antivliwal cd4(+) t cell responses  Academic Article
  • Cutting edge: IL-13Rα1 expression in dopaminergic neurons contributes to their oxidative stress-mediated loss following chronic peripheral treatment with lipopolysaccharide  Academic Article
  • Cutting edge: Impaired glycosphingolipid trafficking and NKT cell development in mice lacking Niemann-Pick type C1 protein  Academic Article
  • Cutting edge: Priming of NK cells by IL-18  Academic Article
  • Cutting edge: Recent immune status determines the source of antigens that drive homeostatic t cell expansion  Academic Article
  • Cutting edge: dendritic epidermal gamma delta T cell ligands are rapidly and locally expressed by keratinocytes following cutaneous wounding  Academic Article
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  • Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities  Academic Article
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  • Cytokine regulation of TNF-alpha mRNA and protein production by unprimed macrophages from C57Bl/6 and NZW mice  Academic Article
  • Cytoprotective activated protein C averts Nlrp3 inflammasome-induced ischemia-reperfusion injury via mTORC1 inhibition  Academic Article
  • Cytoprotective-selective activated protein C therapy for ischaemic stroke  Academic Article
  • DISC1 regulates trafficking and processing of APP and Aβ generation  Academic Article
  • DNA immunization induces antibody and cytotoxic T cell responses to hepatitis B core antigen in H-2b mice  Academic Article
  • DNA immunization with minigenes: Low frequency of memory cytotoxic t lymphocytes and inefficient antiviral protection are rectified by ubiquitination  Academic Article
  • DNA immunization: Ubiquitination of a viral protein enhances cytotoxic t-lymphocyte induction and antiviral protection but abrogates antibody induction  Academic Article
  • DNA vaccination against vegf receptor 2 reduces atherosclerosis in ldl receptor-deficient mice  Academic Article
  • DNA vaccination with plasmids encoding the intracellular (HBcAg) or secreted (HBeAg) form of the core protein of hepatitis B virus primes T cell responses to two overlapping Kb- and Kd-restricted epitopes  Academic Article
  • DNA-based vaccines activate innate and adaptive antitumor immunity by engaging the nkg2d receptor  Academic Article
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  • Darwinian evolution of prions in cell culture  Academic Article
  • Decay-accelerating factor 1 (daf1) deficiency exacerbates xenobiotic-induced autoimmunity  Academic Article
  • Decreased aggression and increased repetitive behavior in Pten haploinsufficient mice  Academic Article
  • Decreased brain reward function during nicotine withdrawal in c57bl6 mice: Evidence from intracranial self-stimulation (icss) studies  Academic Article
  • Decreased immobility in swimming test by homologous interferon-alpha in mice accompanied with increased cerebral tryptophan level and serotonin turnover  Academic Article
  • Decreased phospho-Akt signaling in a mouse model of total parenteral nutrition: a potential mechanism for the development of intestinal mucosal atrophy  Academic Article
  • Deep proteome mapping of mouse kidney based on OFFGel prefractionation reveals remarkable protein post- translational modifications  Academic Article
  • Deep sequencing of the murine Igh repertoire reveals complex regulation of nonrandom V gene rearrangement frequencies  Academic Article
  • Deep sequencing reveals cell-type-specific patterns of single-cell transcriptome variation  Academic Article
  • Deep-brain magnetic stimulation promotes adult hippocampal neurogenesis and alleviates stress-related behaviors in mouse models for neuropsychiatric disorders  Academic Article
  • Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene  Academic Article
  • Defective lymphotoxin-β receptor-induced NF-κB transcriptional activity in NIK-deficient mice  Academic Article
  • Defects in skin γδ T cell function contribute to delayed wound repair in rapamycin-treated mice  Academic Article
  • Defects in the acquisition of CD8 T cell effector function after priming with tumor or soluble antigen can be overcome by the addition of an OX40 agonist  Academic Article
  • Deficiencies in tRNA synthetase editing activity cause cardioproteinopathy  Academic Article
  • Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis  Academic Article
  • Defining parameters for successful immunocytotherapy of persistent viral infection  Academic Article
  • Defining the conformational features of anchorless, poorly neuroinvasive prions  Academic Article
  • Defining the critical hypoxic threshold that promotes vascular remodeling in the brain  Academic Article
  • Definition of IFN-γ-related pathways critical for chemically-induced systemic autoimmunity  Academic Article
  • Delayed and accelerated aging share common longevity assurance mechanisms  Academic Article
  • Deletion of IgG-switched autoreactive B cells and defects in Fas(lpr) lupus mice  Academic Article
  • Deletion of PREPl causes growth impairment and hypotonia in mice  Academic Article
  • Deletion of ghrelin impairs neither growth nor appetite  Academic Article
  • Deletion of lysophosphatidic acid receptor LPA1 reduces neurogenesis in the mouse dentate gyrus  Academic Article
  • Deletion of p21 (WAF-1/Cip1) does not induce systemic autoimmunity in female BXSB mice  Academic Article
  • Deletion of the nucleotide excision repair gene ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions  Academic Article
  • Deletions within the 5 ' utr of coxsackievirus b3: Consequences for virus translation and replication  Academic Article
  • Delineation of spontaneous erythrocyte autoantibody responses of nzb and other strains of mice  Academic Article
  • Delta-9,11 modification of glucocorticoids dissociates nuclear factor-κB inhibitory efficacy from glucocorticoid response element-associated side effects  Academic Article
  • Demonstration of developmental anomalies in mouse fetuses by transfer of murine cytomegalovirus DNA-injected eggs to surrogate mothers  Academic Article
  • Dendritic BDNF synthesis is required for late-phase spine maturation and recovery of cortical responses following sensory deprivation  Academic Article
  • Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation  Academic Article
  • Dendritic cell immunization breaks cytotoxic T lymphocyte tolerance in hepatitis B virus transgenic mice  Academic Article
  • Dendritic cell-based genetic immunization in mice with a recombinant adenovirus encoding murine TRP2 induces effective anti-melanoma immunity  Academic Article
  • Dendritic cell-secreted cytotoxic T-lymphocyte-associated protein-4 regulates the T-cell response by downmodulating bystander surface B7  Academic Article
  • Dendritic cells genetically engineered to express IL-4 exhibit enhanced IL-12p70 production in response to CD40 ligation and accelerate organ allograft rejection  Academic Article
  • Dendritic epidermal T cells regulate skin antimicrobial barrier function  Academic Article
  • Dendritic epidermal T cells regulate skin homeostasis through local production of insulin-like growth factor 1  Academic Article
  • Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin  Academic Article
  • Dense nuclear cataract caused by the γB-crystallin S11R point mutation  Academic Article
  • Dependence-induced increases in ethanol self-administration in mice are blocked by the crf, receptor antagonist antalarmin and by crf, receptor knockout  Academic Article
  • Depletion of neutrophils blocks the recruitment of antigen-nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus-specific cytotoxic T lymphocytes  Academic Article
  • Deregulated cyclin E promotes p53 loss of heterozygosity and tumorigenesis in the mouse mammary gland  Academic Article
  • Derivation of HLA-A11/Kb transgenic mice: functional CTL repertoire and recognition of human A11-restricted CTL epitopes  Academic Article
  • Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor  Academic Article
  • Design, synthesis and SAR of novel glucokinase activators  Academic Article
  • Design, synthesis, and characterization of alpha-ketoheterocycles that additionally target the cytosolic port Cys269 of fatty acid amide hydrolase  Academic Article
  • Detection of h-2 antigens in serum  Academic Article
  • Detection of low-avidity CD4(+) T cells using recombinant artificial APC: following the antiovalbumin immune response  Academic Article
  • Determination of key aspects of precursor cell proliferation, cell cycle length and kinetics in the adult mouse subgranular zone  Academic Article
  • Development and maintenance of a b220(-) memory b cell compartment  Academic Article
  • Development of cataractous macrophthalmia in mice expressing an active MEK1 in the lens  Academic Article
  • Development of ecdysone-regulated lentiviral vectors  Academic Article
  • Development of functionally selective, small molecule agonists at kappa opioid receptors  Academic Article
  • Development of immature thymocytes - initiation of CD3, CD4, and CD8 acquisition parallels down-regulation of the interleukin-2 receptor alpha-chain  Academic Article
  • Development of lupus in BXSB mice is independent of IL-4  Academic Article
  • Developmental expression of the alpha(iel)beta(7) integrin on t-cell receptor-gamma-delta and t-cell receptor-alpha-beta t-cells  Academic Article
  • Developmental regulation of TREM2 and DAP12 expression in the murine CNS: implications for Nasu-Hakola disease  Academic Article
  • Developmental regulation of beta 1 integrins during angiogenesis in the central nervous system  Academic Article
  • Diabetes accelerates retinal ganglion cell dysfunction in mice lacking sigma receptor 1  Academic Article
  • Didehydro-cortistatin A inhibits HIV-1 Tat mediated neuroinflammation and prevents potentiation of cocaine reward in Tat transgenic mice  Academic Article
  • Diet and feeding pattern affect the diurnal dynamics of the gut microbiome  Academic Article
  • Diet-genotype interactions in the development of the obese, insulin-resistant phenotype of C57BL/6J mice lacking melanocortin-3 or-4 receptors  Academic Article
  • Differences in the degree of depletion, rate of recovery, and the preferential elimination of naive cd4(+) t-cells by anti-cd4 monoclonal-antibody (gk1.5) in young and aged mice  Academic Article
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  • Differences in the liability to self-administer intravenous cocaine between c57bl/6xsjl and balb/cbyj mice  Academic Article
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  • Disruption of myd88 signaling suppresses hemophagocytic lymphohistiocytosis in mice  Academic Article
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  • ENU-induced phenovariance in mice: Inferences from 587 mutations  Academic Article
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  • Effective therapy of the LP-BM5 murine retrovirus-induced lymphoproliferative immunodeficiency disease with diethyldithiocarbamate  Academic Article
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  • Effects of chronic overexpression of interleukin-1 receptor antagonist in a model of permanent focal cerebral ischemia in mouse  Academic Article
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  • Efficient transfer and sustained high expression of the human glucocerebrosidase gene in mice and their functional macrophages following transplantation of bone-marrow transduced by a retroviral vector  Academic Article
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  • Embryonic to adult conversion of neural cell-adhesion molecules in normal and staggerer mice  Academic Article
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  • Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection  Academic Article
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  • Endotoxin stimulates expression of the murine urokinase receptor gene in vivo  Academic Article
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  • Enhanced thrombosis in atherosclerosis-prone mice is associated with increased arterial expression of plasminogen activator inhibitor-1  Academic Article
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  • Enterotoxin residues determining t-cell receptor v-beta binding-specificity  Academic Article
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  • Enzymatic machinery for endocannabinoid biosynthesis associated with calcium stores in glutamatergic axon terminals  Academic Article
  • EphA2 and ephrin-A5 are not a receptor-ligand pair in the ocular lens  Academic Article
  • Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation  Academic Article
  • Epigenetic priming of memory updating during reconsolidation to attenuate remote fear memories  Academic Article
  • Epithelial p38 alpha controls immune cell recruitment in the colonic mucosa  Academic Article
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  • Essential function of NHE8 in mouse retina demonstrated by AAV-mediated CRISPR/Cas9 knockdown  Academic Article
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  • Ethanol consumption in mice: Relationships with circadian period and entrainment  Academic Article
  • Evaluating the immunogenicity and protective efficacy of a DNA vaccine encoding lassa virus nucleoprotein  Academic Article
  • Evaluation of fatty acid amides in the carrageenan-induced paw edema model  Academic Article
  • Evaluation of quinacrine treatment for prion diseases  Academic Article
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  • Event-related oscillations in mice: Effects of stimulus characteristics  Academic Article
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  • Evidence that TRPC1 is involved in hippocampal glutamate-induced cell death  Academic Article
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  • Ex vivo-transduced autologous skin fibroblasts expressing human Lim mineralization protein-3 efficiently form new bone in animal models  Academic Article
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  • Exposure of plasmodium sporozoites to the intracellular concentration of potassium enhances infectivity and reduces cell passage activity  Academic Article
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  • Expression of an adenovirally encoded lymphotoxin-beta inhibitor prevents clearance of Listeria monocytogenes in mice  Academic Article
  • Expression of cytotactin in the normal and regenerating neuromuscular system  Academic Article
  • Expression of novel extracellular sulfatases Sulf-1 and Sulf-2 in normal and osteoarthritic articular cartilage  Academic Article
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  • Extensive vascular remodeling in the spinal cord of pre-symptomatic experimental autoimmune encephalomyelitis mice; increased vessel expression of fibronectin and the alpha 5 beta 1 integrin  Academic Article
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  • FTY720 (fingolimod) modulates the severity of viral-induced encephalomyelitis and demyelination  Academic Article
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  • Factors limiting the immunogenicity of hiv-1 gp120 envelope glycoproteins  Academic Article
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  • Fatty acid amide hydrolase deficiency limits early pregnancy events  Academic Article
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  • Fatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injury  Academic Article
  • Fatty acid amide hydrolase shapes NKT cell responses by influencing the serum transport of lipid antigen in mice  Academic Article
  • Fibrin deposition in tissues from endotoxin-treated mice correlates with decreases in the expression of urokinase-type but not tissue-type plasminogen activator  Academic Article
  • Fibronectin- and vitronectin-induced microglial activation and matrix metalloproteinase-9 expression is mediated by integrins alpha(5)beta(1) and alpha(v)beta(5)  Academic Article
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  • First reported patient with human ercc1 deficiency has cerebro-oculo-facio-skeletal syndrome with a mild defect in nucleotide excision repair and severe developmental failure  Academic Article
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  • Follicular helper NKT cells induce limited B cell responses and germinal center formation in the absence of CD4(+) T cell help  Academic Article
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  • Formaldehyde scavengers function as novel antigen retrieval agents  Academic Article
  • Foxp3 expression is required for the induction of therapeutic tissue tolerance  Academic Article
  • Frequencies of T cells secreting IL-2 and/or IL-4 among unprimed CD4+ populations. Evidence that clones secreting IL-2 and IL-4 give rise to clones which secrete only IL-4  Academic Article
  • Frequent spontaneous seizures followed by spatial working memory/anxiety deficits in mice lacking sphingosine 1-phosphate receptor 2  Academic Article
  • Full fatty acid amide hydrolase inhibition combined with partial monoacylglycerol lipase inhibition: augmented and sustained antinociceptive effects with reduced cannabimimetic side effects in mice  Academic Article
  • Full pharmacological efficacy of a novel S1P1 agonist that does not require S1P-like headgroup interactions  Academic Article
  • Full-length proteins attached to the hiv tat protein transduction domain are neither transduced between cells, nor exhibit enhanced immunogenicity  Academic Article
  • Functional T lymphocytes are required for a murine retrovirus-induced immunodeficiency disease (MAIDS)  Academic Article
  • Functional and molecular characterization of single, (4-hydroxy-3-nitrophenyl) acetyl (np)-specific, igg(1+) b-cells from antibody-secreting and memory b-cell pathways in the c57bl/6 immune-response to np  Academic Article
  • Functional b cell receptor transgene allows efficient il-7-independent maturation of b cell precursors  Academic Article
  • Functional expression of murine v213 pheromone receptors involves selective association with the m10 and m1 families of mhc class ib molecules  Academic Article
  • Functional immunoglobulin transgenes guide ordered b-cell differentiation in rag-1-deficient mice  Academic Article
  • Functional pharmacology of H-1 histamine receptors expressed in mouse preoptic/anterior hypothalamic neurons  Academic Article
  • Functional role and therapeutic implications of neuronal caspase-1 and-3 in a mouse model of traumatic spinal cord injury  Academic Article
  • G beta 5 recruits R7 RGS proteins to GIRK channels to regulate the timing of neuronal inhibitory signaling  Academic Article
  • G beta 5-RGS complexes are gatekeepers of hyperactivity involved in control of multiple neurotransmitter systems  Academic Article
  • G protein-coupled receptor 21 deletion improves insulin sensitivity in diet-induced obese mice  Academic Article
  • GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease  Academic Article
  • GADD4gamma regulates the thermogenic capacity of brown adipose tissue  Academic Article
  • GATA family members as inducers for cellular reprogramming to pluripotency  Academic Article
  • GIRK3 gates activation of the mesolimbic dopaminergic pathway by ethanol  Academic Article
  • GPR179 is required for high sensitivity of the mGluR6 signaling cascade in depolarizing bipolar cells  Academic Article
  • GalR2-positive allosteric modulator exhibits anticonvulsant effects in animal models  Academic Article
  • Galanin type 1 receptor knockout mice show altered responses to high-fat diet and glucose challenge  Academic Article
  • Galanin type 1 receptor knockout mice show altered responses to high-fat diet and glucose challenge  Academic Article
  • Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests  Academic Article
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  • Gamma delta t cells are reduced and rendered unresponsive by hyperglycemia and chronic tnf alpha in mouse models of obesity and metabolic disease  Academic Article
  • Gamma oscillations organize top-down signalling to hypothalamus and enable food seeking  Academic Article
  • Ganoderma lucidum polysaccharides enhance cd14 endocytosis of lps and promote tlr4 signal transduction of cytokine expression  Academic Article
  • Gbeta5 is required for normal light responses and morphology of retinal ON-bipolar cells  Academic Article
  • Gene expression during the priming phase of liver regeneration after partial hepatectomy in mice  Academic Article
  • Gene expression in scrapie - cloning a new scrapie-responsive gene and the identification of increased levels of seven other mRNA transcripts  Academic Article
  • Gene expression profile of murine long-term reconstituting vs. Short-term reconstituting hematopoietic stem cells  Academic Article
  • Gene therapy model for stromal precursor cells of hematopoietic microenvironment  Academic Article
  • Generation and analysis of an rna vaccine that protects against coxsackievirus b3 challenge  Academic Article
  • Generation and characterization of a recombinant vesicular stomatitis virus expressing the glycoprotein of Borna disease virus  Academic Article
  • Generation and phenotypic characterization of a galanin overexpressing mouse  Academic Article
  • Genetic ablation of a mouse gene expressed specifically in brain  Academic Article
  • Genetic analysis of the corticosterone response to ethanol in bxd recombinant inbred mice  Academic Article
  • Genetic and physical mapping of the Lps locus: Identification of the Toll-4 receptor as a candidate gene in the critical region  Academic Article
  • Genetic deletion of platelet glycoprotein Ib alpha but not its extracellular domain protects from atherosclerosis  Academic Article
  • Genetic differences in behavioral sensitivity to a neuroactive steroid  Academic Article
  • Genetic differences in hypothalamic-pituitary-adrenal axis responsiveness to acute ethanol and acute ethanol withdrawal  Academic Article
  • Genetic disruption of gamma-melanocyte-stimulationg hormone signaling leads to salt-sensitive hypertension in the mouse  Academic Article
  • Genetic diversity of murine rheumatoid factors  Academic Article
  • Genetic factors influence cataract formation in α(3) connexin knockout mice  Academic Article
  • Genetic linkage of the cytolytic T lymphocyte repertoire and immunoglobulin heavy chain genes  Academic Article
  • Genetic loss of FAAH compromises male fertility in mice  Academic Article
  • Genetic manipulation of the ghrelin signaling system in male mice reveals bone compartment specificity of acylated and unacylated ghrelin in the regulation of bone remodeling  Academic Article
  • Genetic modulation of T cell receptor gene segment usage during somatic recombination  Academic Article
  • Genetic regulation of the immune response to hepatitis B surface antigen (HBsAg). I. H-2 restriction of the murine humoral immune response to the a and d determinants of HBsAg  Academic Article
  • Genetic regulation of the immune response to hepatitis B surface antigen (HBsAg). II. Qualitative characteristics of the humoral immune response to the a, d, and y determinants of HBsAg  Academic Article
  • Genetic regulation of the immune response to hepatitis B surface antigen (HBsAg). III. Circumvention of nonresponsiveness in mice bearing HBsAg nonresponder haplotypes  Academic Article
  • Genetic regulation of the immune response to hepatitis B surface antigen (HBsAg). IV. Distinct H-2-linked Ir genes control antibody responses to different HBsAg determinants on the same molecule and map to the I-A and I-C subregions  Academic Article
  • Genetic regulation of the immune response to hepatitis B surface antigen (HBsAg). VI. T cell fine specificity  Academic Article
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  • Genome-wide gene expression profiles of the developing mouse hippocampus  Academic Article
  • Genomic and biological characterization of aggressive and docile strains of lymphocytic choriomeningitis virus rescued from a plasmid-based reverse-genetics system  Academic Article
  • Genomic characterization of the lysophosphatidic acid receptor gene, lPA2/Edg4, and identification of a frameshift mutation in a previously characterized cDNA  Academic Article
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  • Immune tolerance negatively regulates B cells in knock-in mice expressing broadly neutralizing HIV antibody 4E10  Academic Article
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  • Immunomodulation by adenoviral-mediated SCD40-Ig gene therapy for mouse allogeneic islet transplantation  Academic Article
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  • Impairment of chaperone-mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis  Academic Article
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  • In a transgenic model of spontaneous autoimmune diabetes, expression of a protective class II MHC molecule results in thymic deletion of diabetogenic CD8+ T cells  Academic Article
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  • In vitro and in vivo neurotoxicity of prion protein oligomers  Academic Article
  • In vivo RNA interference screens identify regulators of antiviral CD4(+) and CD8(+) T cell differentiation  Academic Article
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  • In vivo expression of perforin by CD8+ lymphocytes during an acute viral infection  Academic Article
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  • In vivo relevance for platelet glycoprotein Ib alpha residue Tyr276 in thrombus formation  Academic Article
  • In vivo stabilization of mutant human transthyretin in transgenic mice  Academic Article
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  • Induction of B lymphocyte proliferation by monoclonal anti-Lyb 2 antibody  Academic Article
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  • Inhibition of hepatitis B virus replication during adenovirus and cytomegalovirus infections in transgenic mice  Academic Article
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  • Insulin continues to induce plasminogen activator inhibitor 1 gene expression in insulin-resistant mice and adipocytes  Academic Article
  • Insulin-like growth factor-binding protein 2 secreted by a tumorigenic cell line supports ex vivo expansion of mouse hematopoietic stem cells  Academic Article
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  • Interferon-gamma is essential for destruction of beta cells and development of insulin-dependent diabetes mellitus  Academic Article
  • Interferon-gamma is required for lupus-like disease and lymphoaccumulation in mrl-lpr mice  Academic Article
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  • Interferon-regulated pathways that control hepatitis B virus replication in transgenic mice  Academic Article
  • Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype cd8(+) t cells  Academic Article
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  • Interleukin 7 regulates the survival and generation of memory cd4 cells  Academic Article
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  • Interleukin-17 promotes angiogenesis and tumor growth  Academic Article
  • Interleukin-18 controls energy homeostasis by suppressing appetite and feed efficiency  Academic Article
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  • Interleukin-18 null mutation increases weight and food intake and reduces energy expenditure and lipid substrate utilization in high-fat diet fed mice  Academic Article
  • Interleukin-1β contributes to the generation of experimental febrile seizures  Academic Article
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  • Interleukin-7 is required for CD4(+) T cell activation and autoimmune neuroinflammation  Academic Article
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  • Junctional diversity in the absence of N-regions - neonatal T-cell receptor beta-chain junctional sequences are more heterogeneous than neonatal T-cell receptor-gamma-delta or IgH junctions  Academic Article
  • K33-linked polyubiquitination of T cell receptor-zeta regulates proteolysis-independent T cell signaling  Academic Article
  • Kidney preservation by bone marrow cell transplantation in hereditary nephropathy  Academic Article
  • Kinetic and immunochemical studies of a receptor-like protein that binds aromatic hydrocarbons  Academic Article
  • Kinetics of protective antibodies are determined by the viral surface antigen  Academic Article
  • Kinetics of steady-state differentiation and mapping of intrathymic-signaling environments by stem cell transplantation in nonirradiated mice  Academic Article
  • Knockout of toll-like receptor-2 attenuates both the proinflammatory state of diabetes and incipient diabetic nephropathy  Academic Article
  • Knockout of toll-like receptor-4 attenuates the pro-inflammatory state of diabetes  Academic Article
  • Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis  Academic Article
  • Kv4.2 mediates histamine modulation of preoptic neuron activity and body temperature  Academic Article
  • LP-BM5 murine retrovirus-induced immunodeficiency disease in allogeneic SCID chimeric mice. Inability to recognize a putative viral superantigen does not prevent induction of disease  Academic Article
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  • LPA1 receptor activation promotes renal interstitial fibrosis  Academic Article
  • LPA1-induced cytoskeleton reorganization drives fibrosis through CTGF-dependent fibroblast proliferation  Academic Article
  • LPA3 receptor mediates chemotaxis of immature murine dendritic cells to unsaturated lysophosphatidic acid (LPA)  Academic Article
  • LXR-mediated inhibition of CD4(+) T helper cells  Academic Article
  • Lack of self-administration of cocaine in dopamine d-1 receptor knock-out mice  Academic Article
  • Lack of stimulant and anxiolytic-like effects of ethanol and accelerated development of ethanol dependence in mu-opioid receptor knockout mice  Academic Article
  • Lacrimal Gland Myoepithelial Cells Are Altered in a Mouse Model of Dry Eye Disease  Academic Article
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  • Late-onset inner retinal dysfunction in mice lacking sigma receptor 1 (sigma r1)  Academic Article
  • Lcmv-specific, class-ii restricted cytotoxic t-cells in beta-2-microglobulin deficient mice  Academic Article
  • Learned recognition of maternal signature odors mediates the first suckling episode in mice  Academic Article
  • Leptin promotes vascular remodeling and neointimal growth in mice  Academic Article
  • Leptin-dependent platelet aggregation and arterial thrombosis suggests a mechanism for atherothrombotic disease in obesity  Academic Article
  • Lethal alpha-thalassemia created by gene targeting in mice and its genetic rescue  Academic Article
  • Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet  Academic Article
  • Leukocyte transglutaminase 2 expression limits atherosclerotic lesion size  Academic Article
  • Ligand activation of ERRα by cholesterol mediates statin and bisphosphonate effects  Academic Article
  • Ligation of the OX40 co-stimulatory receptor reverses self-Ag and tumor-induced CD8 T-cell anergy in vivo  Academic Article
  • Limited diversity of t-cell receptor gamma-chain expression of murine thy-1+ dendritic epidermal-cells revealed by v-gamma-3-specific monoclonal-antibody  Academic Article
  • Limits of a deletion spanning Tlr4 in C57BL/10ScCr mice  Academic Article
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  • Linear padre t helper epitope and carbohydrate b cell epitope conjugates induce specific high titer igg antibody responses  Academic Article
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  • Lipopolysaccharide sensing an important factor in the innate immune response to gram-negative bacterial infections: Benefits and hazards of lps hypersensitivity  Academic Article
  • Lipopolysaccharide-induced il-12 expression in the central nervous system and cultured astrocytes and microglia  Academic Article
  • Lipoprotein-derived lysophosphatidic acid promotes atherosclerosis by releasing CXCL1 from the endothelium  Academic Article
  • Lithium ameliorates altered glycogen synthase kinase-3 and behavior in a mouse model of fragile x syndrome  Academic Article
  • Liver-expressed Igκ superantigen induces tolerance of polyclonal B cells by clonal deletion not κ to λ receptor editing  Academic Article
  • Local not systemic modulation of dendritic cell s1p receptors in lung blunts virus-specific immune responses to influenza  Academic Article
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  • Loci predisposing to autoimmunity in MRL-Fas(lpr) and C57BL/6-Fas(lpr) mice  Academic Article
  • Long latency event-related potentials in mice: Effects of stimulus characteristics and strain  Academic Article
  • Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling  Academic Article
  • Loss of CD4 T-cell-dependent tolerance to proteins with modified amino acids  Academic Article
  • Loss of bax alters tumor spectrum and tumor numbers in arf-deficient mice  Academic Article
  • Loss of medial septal modulation of dentate gyrus physiology in young mice overexpressing human β-amyloid precursor protein  Academic Article
  • Loss of nicotine-induced behavioral sensitization in mu-opioid receptor knockout mice  Academic Article
  • Loss of sex discrimination and male-male aggression in mice deficient for trp2  Academic Article
  • Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome  Academic Article
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  • Lps2: A new locus required for responses to lipopolysaccharide, revealed by germline mutagenesis and phenotypic screening  Academic Article
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  • Lxr-dependent gene expression is important for macrophage survival and the innate immune response  Academic Article
  • Ly phenotype and mechanism of action of mouse neonatal suppressor T cells  Academic Article
  • Lyb-7, a new B cell alloantigen controlled by genes linked to the IgCH locus  Academic Article
  • Lymphocyte-mediated alopecia in c57bl/6 mice following successful immunotherapy for melanoma  Academic Article
  • Lymphoid reservoirs of antigen-specific memory t helper cells  Academic Article
  • Lymphoproliferative disease and autoimmunity in mice with increased mir-17-92 expression in lymphocytes  Academic Article
  • Lymphotoxin-alpha- and lymphotoxin-beta-deficient mice differ in susceptibility to scrapie: Evidence against dendritic cell involvement in neuroinvasion  Academic Article
  • Lysophosphatidic acid receptor-2 deficiency confers protection against bleomycin-induced lung injury and fibrosis in mice  Academic Article
  • Lysophosphatidic acid stimulates the intestinal brush border NA(+)/H(+) exchanger 3 and fluid absorption via LPA(5) and NHERF  Academic Article
  • Lysophosphatidic acid-3 receptor-mediated feed-forward production of lysophosphatidic acid: An initiator of nerve injury-induced neuropathic pain  Academic Article
  • Lysophosphatidylserine suppression of T-cell activation via GPR174 requires Gs proteins  Academic Article
  • Lysosomal glycosphingolipid recognition by NKT cells  Academic Article
  • MAPK phosphatase-1 is required for regulatory natural autoantibody-mediated inhibition of TLR responses  Academic Article
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  • MKK3 mitogen-activated protein kinase pathway mediates carbon monoxide-induced protection against oxidant-induced lung injury  Academic Article
  • MMPs are required for recruitment of antigen-nonspecific mononuclear cells into the liver by CTLs  Academic Article
  • Macrophage VLDL receptor promotes PAFAH secretion in mother's milk and suppresses systemic inflammation in nursing neonates  Academic Article
  • Macrophage i-a/i-e expression and macrophage-stimulating lymphokines in murine lupus  Academic Article
  • Macrophage requirement for the in vitro response to TNP Ficoll: a thymic independent antigen  Academic Article
  • Maintaining retinal astrocytes normalizes revascularization and prevents vascular pathology associated with oxygen-induced retinopathy  Academic Article
  • Maintenance of T cell specification and differentiation requires recurrent notch receptor-ligand interactions  Academic Article
  • Male germ cells support long-term propagation of Zika virus  Academic Article
  • Mammalian TRIM67 functions in brain development and behavior  Academic Article
  • Mammalian circadian autoregulatory loop: A timeless ortholog and mper1 interact and negatively regulate clock-bmal1-induced transcription  Academic Article
  • Manipulating a "cocaine engram" in mice  Academic Article
  • Manipulation of Panx1 activity increases the engraftment of transplanted lacrimal gland epithelial progenitor cells  Academic Article
  • Manufacture of a functional cdna for the h-2db molecule using a retroviral shuttle vector  Academic Article
  • Mapping loci for pentylenetetrazol-induced seizure susceptibility in mice  Academic Article
  • Mapping murine loci for seizure response to kainic acid  Academic Article
  • Mapping of epitopes recognized by alloreactive cytotoxic T lymphocytes using inhibition by MHC peptides  Academic Article
  • Mapping of the full length and the truncated interleukin-18 receptor alpha in the mouse brain  Academic Article
  • Mapping precursor movement through the postnatal thymus reveals specific microenvironments supporting defined stages of early lymphoid development  Academic Article
  • Mapping the innate signaling cascade essential for cytokine storm during influenza virus infection  Academic Article
  • Marked perinatal lethality and cellular signaling deficits in mice null for the two sphingosine 1-phosphate (S1p) receptors, S1p(2)/LP(B2)/EDG-5 and S1P(3)/LP(B3)/EDG-3  Academic Article
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  • Massively parallel sequencing of the mouse exome to accurately identify rare, induced mutations: An immediate source for thousands of new mouse models  Academic Article
  • Mast cell function is not altered by Coronin-1A deficiency  Academic Article
  • Maternal PPAR gamma protects nursing neonates by suppressing the production of inflammatory milk  Academic Article
  • Maternal b lymphocytes specific for paternal histocompatibility antigens are partially deleted during pregnancy  Academic Article
  • Maternal western diet causes inflammatory milk and TLR2/4-dependent neonatal toxicity  Academic Article
  • Matrix metalloproteinase-9 mediates post-hypoxic vascular pruning of cerebral blood vessels by degrading laminin and claudin-5  Academic Article
  • Mature microglia resemble immature antigen-presenting cells  Academic Article
  • MeCP2 regulates ethanol sensitivity and intake  Academic Article
  • Measles virus infects and suppresses proliferation of t lymphocytes from transgenic mice bearing human signaling lymphocytic activation molecule  Academic Article
  • Measles virus interacts with human slam receptor on dendritic cells to cause immuno suppression  Academic Article
  • Mechanisms and consequences of ebolavirus-induced lymphocyte apoptosis  Academic Article
  • Mechanisms of class-I restricted immunopathology - A transgenic mouse model of fulminant-hepatitis  Academic Article
  • Mechanisms of group b streptococcal-induced apoptosis of murine macrophages  Academic Article
  • Mechanistic and pharmacological characterization of PF-04457845: A highly potent and selective fatty acid amide hydrolase inhibitor that reduces inflammatory and noninflammatory pain  Academic Article
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  • Melanocortin-4 receptor is required for acute homeostatic responses to increased dietary fat  Academic Article
  • Melanocortins induce interleukin 6 gene expression and secretion through melanocortin receptors 2 and 5 in 3T3-L1 adipocytes  Academic Article
  • Melanoma immunotherapy by targeted IL-2 depends on CD4(+) T-cell help mediated by CD40/CD40L interaction  Academic Article
  • Melanopsin (Opn4) requirement for normal light-induced circadian phase shifting  Academic Article
  • Memory CD4 T cells direct protective responses to influenza virus in the lungs through helper-independent mechanisms  Academic Article
  • Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects  Academic Article
  • Mesenchymal stem cells enhance survival and bacterial clearance in murine Escherichia coli pneumonia  Academic Article
  • Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota  Academic Article
  • Metabolic benefit of chronic caloric restriction and activation of hypothalamic AGRP/NPY neurons in male mice is independent of ghrelin  Academic Article
  • Metabolic characterization of a mouse deficient in all known leptin receptor isoforms  Academic Article
  • Metabolic damage and premature thymus aging caused by stromal catalase deficiency  Academic Article
  • Metabolic depression and increased reactive oxygen species production by isolated mitochondria at moderately lower temperatures  Academic Article
  • Metabolomic profiling reveals severe skeletal muscle group-specific perturbations of metabolism in aged FBN rats  Academic Article
  • Metformin inhibits hepatic mTORC1 signaling via dose-dependent mechanisms involving AMPK and the TSC complex  Academic Article
  • Mice deficient in stem cell antigen-1 (sca1, ly-6a/e) develop normal primary and memory cd4(+) and cd8(+) t-cell responses to virus infection  Academic Article
  • Mice devoid of interferon regulatory factor-1 (irf-1) show normal expression of type-i interferon genes  Academic Article
  • Mice devoid of prion protein have cognitive deficits that are rescued by reconstitution of PrP in neurons  Academic Article
  • Mice lacking 5-ht7 receptors show specific impairments in contextual learning  Academic Article
  • Mice lacking the beta4 subunit of the nicotinic acetylcholine receptor show memory deficits, altered anxiety- and depression-like behavior, and diminished nicotine-induced analgesia  Academic Article
  • Mice lacking tropomodulin-2 show enhanced long-term potentiation, hyperactivity, and deficits in learning and memory  Academic Article
  • Mice transgenic for human TTR have the same frequency of renal TTR deposition whether maintained in conventional or specific pathogen free environments  Academic Article
  • Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function  Academic Article
  • MicroRNA-135b promotes cancer progression by acting as a downstream effector of oncogenic pathways in colon cancer  Academic Article
  • MicroRNA-140 plays dual roles in both cartilage development and homeostasis  Academic Article
  • MicroRNA-17 similar to 92 plays a causative role in lymphomagenesis by coordinating multiple oncogenic pathways  Academic Article
  • MicroRNA-221-222 regulate the cell cycle in mast cells  Academic Article
  • MicroRNAs of the miR-17 similar to 92 family are critical regulators of T-FH differentiation  Academic Article
  • Microassay for determination of hemolytic complement activity in mouse serum  Academic Article
  • Microfluidic amperometric sensor for analysis of nitric oxide in whole blood  Academic Article
  • Microfluidic source-sink model reveals effects of biophysically distinct CXCL12 isoforms in breast cancer chemotaxis  Academic Article
  • Microglia are the major source of TNF-α and TGF-β1 in postnatal glial cultures; regulation by cytokines, lipopolysaccharide, and vitronectin  Academic Article
  • Microglia use multiple mechanisms to mediate interactions with vitronectin; non-essential roles for the highly-expressed alpha v beta 3 and alpha v beta 5 integrins  Academic Article
  • Microglial activation state exerts a biphasic influence on brain endothelial cell proliferation by regulating the balance of tnf and tgf-beta 1  Academic Article
  • Microglial cells respond to amyloidogenic PrP peptide by the production of inflammatory cytokines  Academic Article
  • Microrna-219 modulates nmda receptor-mediated neurobehavioral dysfunction  Academic Article
  • Migration of antigen-specific t cells away from cxcr4-binding human immunodeficiency virus type 1 gp120  Academic Article
  • Mimicking the alloantigenicity of proteins with chemically synthesized peptides differing in single amino-acids  Academic Article
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  • Mir-214-dependent regulation of the Polycomb protein Ezh2 in skeletal muscle and embryonic stem cells  Academic Article
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  • Mitochondrial dysfunction in ataxia-telangiectasia  Academic Article
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  • Modulation of atherosclerosis in mice by toll-like receptor 2  Academic Article
  • Modulation of chemokines and allergic airway inflammation by selective local sphingosine-1-phosphate receptor 1 agonism in lungs  Academic Article
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  • Modulation of the Bcl-2 family blocks sepsis-induced depletion of dendritic cells and macrophages  Academic Article
  • Molecular analysis of the interaction of lcmv with its cellular receptor alpha-dystroglycan  Academic Article
  • Molecular anatomy of antigen-specific cd8(+) t cell engagement and synapse formation in vivo  Academic Article
  • Molecular and circuit-dynamical identification of top-down neural mechanisms for restraint of reward seeking  Academic Article
  • Molecular characterization of single memory b-cells  Academic Article
  • Molecular definition of a major cyto-toxic lymphocyte-t epitope in the glycoprotein of lymphocytic choriomeningitis virus  Academic Article
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  • Molecular imaging reveals rapid reduction of endothelial activation in early atherosclerosis with apocynin independent of antioxidative properties  Academic Article
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  • Molecular pathway to protection from age-dependent photoreceptor degeneration in Mef2 deficiency  Academic Article
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  • Molecularly engineered vaccine which expresses an immunodominant t-cell epitope induces cyto-toxic lymphocytes-t that confer protection from lethal virus-infection  Academic Article
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  • Monoacylglycerol lipase inhibition blocks chronic stress-induced depressive-like behaviors via activation of mTOR signaling  Academic Article
  • Monoclonal anti-H-2Kb antibodies detect serological differences between H-2Kb mutants  Academic Article
  • Monoclonal autoantibodies to nuclear antigens from murine graft-versus-host disease  Academic Article
  • Monocyte chemoattractant protein 1 in obesity and insulin resistance  Academic Article
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  • Morphine-induced physiological and behavioral responses in mice lacking g protein-coupled receptor kinase 6  Academic Article
  • Morphological analysis of the interactions between lymphocytic choriomeningitis virus-specific cloned cytotoxic t-cells and virus-infected targets  Academic Article
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  • Mouse hepatitis-virus type-4 (jhm strain)-induced fatal central nervous-system disease .1. Genetic-control and the murine neuron as the susceptible site of disease  Academic Article
  • Mouse liver-specific CD8(+) T-cells encounter their cognate antigen and acquire capacity to destroy target hepatocytes  Academic Article
  • Mouse model of subretinal neovascularization with choroidal anastomosis  Academic Article
  • Mst1 directs Myosin IIa partitioning of low and higher affinity integrins during T cell migration  Academic Article
  • Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence  Academic Article
  • Mu-opioid receptor knockout mice do not self-administer alcohol  Academic Article
  • Mu-opioid receptors selectively regulate basal inhibitory transmission in the central amygdala: Lack of ethanol interactions  Academic Article
  • Multi-scale correlation structure of gene expression in the brain  Academic Article
  • Multidrug resistance-1 (mdr-1): A new target for t cell-based immunotherapy  Academic Article
  • Multiple defects in antigen presentation and T cell development by mice expressing cytoplasmic tail-truncated CD1d  Academic Article
  • Multiple rearrangements in T-cell receptor alpha-chain genes maximize the production of useful thymocytes  Academic Article
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  • Munc13-4 interacts with syntaxin 7 and regulates late endosomal maturation, endosomal signaling, and TLR9-initiated cellular responses  Academic Article
  • Murine CD14 gene expression in vivo: extramyeloid synthesis and regulation by lipopolysaccharide  Academic Article
  • Murine cytomegalovirus infection down-regulates mhc class ii expression on macrophages by induction of il-10  Academic Article
  • Murine pheromone proteins constitute a context-dependent combinatorial code governing multiple social behaviors  Academic Article
  • Murine susceptibility to mercury .2. Autoantibody profiles and renal immune deposits in hybrid, backcross, and h-2d congenic mice  Academic Article
  • Murine tissue factor gene expression in vivo. Tissue and cell specificity and regulation by lipopolysaccharide  Academic Article
  • Mutability of prions  Academic Article
  • Mutation of the gastric hydrogen-potassium atpase alpha subunit causes iron-deficiency anemia in mice  Academic Article
  • MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands  Academic Article
  • Myc suppression of nfkb2 accelerates lymphomagenesis  Academic Article
  • Myc-mediated proliferation and lymphomagenesis, but not apoptosis, are compromised by e2f1 loss  Academic Article
  • Mycobacteria inhibit nitric oxide synthase recruitment to phagosomes during macrophage infection  Academic Article
  • Myelin oligodendrocyte glycoprotein peptide-induced experimental allergic encephalomyelitis and t cell responses are unaffected by immunoproteasome deficiency  Academic Article
  • Myeloid development is selectively disrupted in PU.1 null mice  Academic Article
  • Myeloid progenitors differentiate into microglia and promote vascular repair in a model of ischemic retinopathy  Academic Article
  • Myeloperoxidase and plasminogen activator inhibitor 1 play a central role in ventricular remodeling after myocardial infarction  Academic Article
  • Myocyte enhancer factor 2C as a neurogenic and antiapoptotic transcription factor in murine embryonic stem cells  Academic Article
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  • N-methyl-D-aspartate receptor subunit NR3A in the retina: developmental expression, cellular localization, and functional aspects  Academic Article
  • N-palmitoyl glycine, a novel endogenous lipid that acts as a modulator of calcium influx and nitric oxide production in sensory neurons  Academic Article
  • NF-kB negatively impacts the myogenic potential of muscle-derived stem cells  Academic Article
  • NF-κB inhibition reveals a novel role for HGF during skeletal muscle repair  Academic Article
  • NKG2D-dependent activation of dendritic epidermal T cells in contact hypersensitivity  Academic Article
  • NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component  Academic Article
  • Natural IgE production in the absence of MHC class II cognate help  Academic Article
  • Natural killer T (NKT)-B-cell interactions promote prolonged antibody responses and long-term memory to pneumococcal capsular polysaccharides  Academic Article
  • Natural killer T cell activation inhibits hepatitis B virus replication in vivo  Academic Article
  • Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria  Academic Article
  • Natural killer cell-mediated contact sensitivity develops rapidly and depends on interferon-α, interferon-γ and interleukin-12  Academic Article
  • Natural killer, but not natural killer T, cells play a necessary role in the promotion of an innate antitumor response induced by IL-18  Academic Article
  • Natural sphingomonas glycolipids vary greatly in their ability to activate natural killer T cells  Academic Article
  • Natural thymocytotoxic autoantibodies in auto-immune and normal mice  Academic Article
  • Nec-1 alleviates cognitive impairment with reduction of Aβ and tau abnormalities in APP/PS1 mice  Academic Article
  • Necessity of lysophosphatidic acid receptor 1 for development of arthritis  Academic Article
  • Negative selection by IgM superantigen defines a B cell central tolerance compartment and reveals mutations allowing escape  Academic Article
  • Negative selection of T cells occurs throughout thymic development  Academic Article
  • Neither b lymphocytes nor antibodies directed against self antigens of the islets of langerhans are required for development of virus-induced autoimmune diabetes  Academic Article
  • Neointimal formation after endovascular arterial injury is markedly attenuated in db/db mice  Academic Article
  • Neonates mount robust and protective adult-like cd8(+)-t-cell responses to DNA vaccines  Academic Article
  • Nesprin 1α2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle  Academic Article
  • Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1  Academic Article
  • Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models  Academic Article
  • Neurobiological signatures of alcohol dependence revealed by protein profiling  Academic Article
  • Neurogenin2 regulates the initial axon guidance of cortical pyramidal neurons projecting medially to the corpus callosum  Academic Article
  • Neuroimmune regulation of alcohol consumption: Behavioral validation of genes obtained from genomic studies  Academic Article
  • Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin-6  Academic Article
  • Neuronal calcium-binding proteins 1/2 localize to dorsal root ganglia and excitatory spinal neurons and are regulated by nerve injury  Academic Article
  • Neuronal death induced by misfolded prion protein is due to NAD(+) depletion and can be relieved in vitro and in vivo by NAD(+) replenishment  Academic Article
  • Neuronal expression of a functional receptor for the C5a complement activation fragment  Academic Article
  • Neuronal production of transthyretin in human and murine Alzheimer's disease: Is it protective?  Academic Article
  • Neuropeptide s reinstates cocaine-seeking behavior and increases locomotor activity through corticotropin-releasing factor receptor 1 in mice  Academic Article
  • Neuroprotection by the NR3A subunit of the NMDA receptor  Academic Article
  • Neuroprotective activities of activated protein C mutant with reduced anticoagulant activity  Academic Article
  • Neuroprotective effect of long-term ndi1 gene expression in a chronic mouse model of parkinson disorder  Academic Article
  • Neurosteroid consumption has anxiolytic effects in mice  Academic Article
  • Neurotoxicity of the putative transmembrane domain of the prion protein  Academic Article
  • Neutrophil activation by the tissue factor/factor viia/par2 axis mediates fetal death in a mouse model of anti phospholipid syndrome  Academic Article
  • New insights on the morphology of adult mouse penis  Academic Article
  • New techniques for imaging, digitization and analysis of three-dimensional neural morphology on multiple scales  Academic Article
  • Nf1 regulates alcohol dependence-associated excessive drinking and gamma-aminobutyric acid release in the central amygdala in mice and is associated with alcohol dependence in humans  Academic Article
  • Nfkb1 is dispensable for myc-induced lymphomagenesis  Academic Article
  • Nicotine withdrawal increases body weight, neuropeptide Y and Agouti-related protein expression in the hypothalamus and decreases uncoupling protein-3 expression in the brown adipose tissue in high-fat fed mice  Academic Article
  • Nk cell-mediated killing of target cells triggers robust antigen-specific t cell-mediated and humoral responses  Academic Article
  • Nk markers are expressed on a high percentage of virus-specific cd8(+) and cd4(+) t cells  Academic Article
  • Nkx2-5(+)islet1(+) mesenchymal precursors generate distinct spleen stromal cell subsets and participate in restoring stromal network integrity  Academic Article
  • Nociceptive sensory neurons drive interleukin-23-mediated psoriasiform skin inflammation  Academic Article
  • Nociceptive signals induce trafficking of TRPA1 to the plasma membrane  Academic Article
  • Nod1 and nod2 are expressed in human and murine renal tubular epithelial cells and participate in renal ischemia reperfusion injury  Academic Article
  • Non-canonical antagonism of PI3K by the kinase Itpkb delays thymocyte β-selection and renders it Notch-dependent  Academic Article
  • Non-classical natural killer T cells modulate plasmid DNA vaccine antigen expression and vaccine-elicited immune responses by MCP-1 secretion after interaction with a beta2-microglobulin-independent CD1d  Academic Article
  • Non-proliferative effects of lysophosphatidic acid enhance cortical growth and folding  Academic Article
  • Noncytopathic clearance of lymphocytic choriomeningitis virus from the hepatocyte  Academic Article
  • Nonneutralizing antibodies binding to the surface glycoprotein of lymphocytic choriomeningitis virus reduce early virus spread  Academic Article
  • Nonoverlapping T and B cell determinants on an hepatitis B surface antigen pre-S(2) region synthetic peptide  Academic Article
  • Nonoverlapping functions for Notch1 and Notch3 during murine steady-state thymic lymphopoiesis  Academic Article
  • Nonproteolytic properties of murine alternatively spliced tissue factor: Implications for integrin-mediated signaling in murine models  Academic Article
  • Nonredundant roles of tirap and myd88 in airway response to endotoxin, independent of trif, il-1 and il-18 pathways  Academic Article
  • Notch promotes vascular maturation by inducing integrin-mediated smooth muscle cell adhesion to the endothelial basement membrane  Academic Article
  • Novel amplifier expression vectors producing higher levels of IL-2 led to slower tumor growth and longer survival in vivo  Academic Article
  • Novel antiviral host factor, TNK1, regulates IFN signaling through serine phosphorylation of STAT1  Academic Article
  • Novel bisaryl substituted thiazoles and oxazoles as highly potent and selective peroxisome proliferator-activated receptor delta agonists  Academic Article
  • Novel lcmv-specific h-2k restricted ctl clones recognize internal viral gene-products and cause cns disease  Academic Article
  • Novel signaling interactions between proteinase-activated receptor 2 and Toll-like receptors in vitro and in vivo  Academic Article
  • Nrf2-dependent suppression of azoxymethane/dextran sulfate sodium-induced colon carcinogenesis by the cinnamon-derived dietary factor cinnamaldehyde  Academic Article
  • Nuclear calcium/calmodulin regulates memory consolidation  Academic Article
  • Nuclear receptor RORα regulates pathologic retinal angiogenesis by modulating SOCS3-dependent inflammation  Academic Article
  • Nuclear receptor/microRNA circuitry links muscle fiber type to energy metabolism  Academic Article
  • Nucleic-acid vaccination primes hepatitis-B virus surface antigen-specific cytotoxic T-lymphocytes in nonresponder mice  Academic Article
  • Nucleophosmin is required for DNA integrity and p19(Arf) protein stability  Academic Article
  • Number of macrophages and distribution of mitotic activity in regressing and progressing Moloney sarcomas  Academic Article
  • O-GlcNAc transferase/host cell factor C1 complex regulates gluconeogenesis by modulating PGC-1α stability  Academic Article
  • O-hydroxyacetamide carbamates as a highly potent and selective class of endocannabinoid hydrolase inhibitors  Academic Article
  • O-mannosyl phosphorylation of alpha-dystroglycan is required for laminin binding  Academic Article
  • OX40 agonist therapy enhances CD8 infiltration and decreases immune suppression in the tumor  Academic Article
  • Obesity enhances the induction of plasminogen activator inhibitor-1 by restraint stress: a possible mechanism of stress-induced renal fibrin deposition in obese mice  Academic Article
  • Obesity, hyperphagia and increased metabolic efficiency in Pc1 mutant mice  Academic Article
  • Obligatory role for complex i inhibition in the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)  Academic Article
  • Olfactory based spatial learning in neonatal mice and its dependence on camkii  Academic Article
  • Oligoclonal antibody targeting ghrelin increases energy expenditure and reduces food intake in fasted mice  Academic Article
  • Oligoclonality and innate-like features in the TCR repertoire of type II NKT cells reactive to a beta-linked self-glycolipid  Academic Article
  • Ongoing murine T1 or T2 immune responses to the hepatitis B surface antigen are excluded from the liver that expresses transgene-encoded hepatitis B surface antigen  Academic Article
  • Ontogeny of mouse T-lymphocyte function  Academic Article
  • Ontogeny of susceptibility of mouse splenic B cells to tolerance induction in vitro by TNP-D-GL  Academic Article
  • Opposing functions of the T cell receptor kinase ZAP-70 in immunity and tolerance differentially titrate in response to nucleotide substitutions  Academic Article
  • Opposing roles of peroxisome proliferator-activated receptor alpha and growth hormone in the regulation of CYP4A11 expression in a transgenic mouse model  Academic Article
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  • Oral administration of fish-oil induces high levels of seric TNF in Trypanosoma cruzi infected C57BL/6 mice  Academic Article
  • Oral exposure to Listeria monocytogenes in aged IL-17RKO mice: A possible murine model to study listeriosis in susceptible populations  Academic Article
  • Oral insulin (human, murine, or porcine) does not prevent diabetes in the non-obese diabetic mouse  Academic Article
  • Orexigenic action of peripheral ghrelin is mediated by neuropeptide Y and agouti-related protein  Academic Article
  • Organ-specific protection against lipopolysaccharide-induced vascular leak is dependent on the endothelial protein C receptor  Academic Article
  • Organic anion transporter 3 contributes to the regulation of blood pressure  Academic Article
  • Organization of spines on the dendrites of purkinje cells  Academic Article
  • Orphan nuclear receptor estrogen-related receptor alpha is essential for adaptive thermogenesis  Academic Article
  • Osteopontin is required for the early onset of high fat diet-induced insulin resistance in mice  Academic Article
  • Ovariectomy and genes encoding core circadian regulatory proteins in murine bone  Academic Article
  • Overcoming T cell tolerance to the hepatitis B virus surface antigen in hepatitis B virus-transgenic mice  Academic Article
  • Overexpression of human apoai transgene provides long-term atheroprotection in ldl receptor-deficient mice  Academic Article
  • Overexpression of interleukin (il)-7 leads to il-15-independent generation of memory phenotype cd8(+) t cells  Academic Article
  • Overexpression of interleukin-10 by activated t lymphocytes inhibits atherosclerosis in ldl receptor-deficient mice by altering lymphocyte and macrophage phenotypes  Academic Article
  • Overlapping and distinct functions of CstF64 and CstF64 tau in mammalian mRNA 3' processing  Academic Article
  • Overproduction of corticotropin-releasing factor in transgenic mice - a genetic model of anxiogenic behavior  Academic Article
  • Oxidation-sensitive polymersomes as vaccine nanocarriers enhance humoral responses against Lassa virus envelope glycoprotein  Academic Article
  • P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice  Academic Article
  • PAD4 is not essential for disease in the K/BxN murine autoantibody-mediated model of arthritis  Academic Article
  • PAD4-mediated neutrophil extracellular trap formation is not required for immunity against influenza infection  Academic Article
  • PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells  Academic Article
  • PER1 phosphorylation specifies feeding rhythm in mice  Academic Article
  • PI3K-mediated negative feedback regulation of IL-12 production in DCs  Academic Article
  • PPAR delta regulates multiple proinflammatory pathways to suppress atherosclerosis  Academic Article
  • PRMT5-mediated regulation of developmental myelination  Academic Article
  • PTD-mediated loading of tumor-seeking lymphocytes with prodrug-activating enzymes  Academic Article
  • PTPN22 alters the development of regulatory T cells in the thymus  Academic Article
  • PTPN22 controls the germinal center by influencing the numbers and activity of T follicular helper cells  Academic Article
  • PU.1 is a lineage-specific regulator of tyrosine phosphatase CD45  Academic Article
  • Palmitoylation-dependent activation of MC1R prevents melanomagenesis  Academic Article
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  • Pancreatic beta-cell neogenesis by direct conversion from mature alpha-cells  Academic Article
  • Pancreatic-islet production of murine interleukin-10 does not inhibit immune-mediated tissue destruction  Academic Article
  • Papillorenal syndrome-causing missense mutations in PAX2/Pax2 result in hypomorphic alleles in mouse and human  Academic Article
  • Parameters governing exhaustion of rare T cell-independent neutralizing IgM-producing B cells after LCMV infection  Academic Article
  • Paranodal reorganization results in the depletion of transverse bands in the aged central nervous system  Academic Article
  • Parkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1  Academic Article
  • Participation of the major histocompatibility complex in antibody recognition of viral antigens expressed on infected cells  Academic Article
  • Passive microfluidic chamber for long-term imaging of axon guidance in response to soluble gradients  Academic Article
  • Pathogenesis of Lassa fever virus infection: I. Susceptibility of mice to recombinant Lassa Gp/LCMV chimeric virus  Academic Article
  • Pathogenesis of the oral route of infection of mice with scrapie and bovine spongiform encephalopathy agents  Academic Article
  • Pathogenic SYNGAP1 mutations impair cognitive development by disrupting maturation of dendritic spine synapses  Academic Article
  • Pathogenic autoantibody production requires loss of tolerance against desmoglein 3 in both T and B cells in experimental pemphigus vulgaris  Academic Article
  • Pathogenic relevance of IgG and IgM antibodies against desmoglein 3 in blister formation in pemphigus vulgaris  Academic Article
  • Patterns of cytokine gene expression by CD4+ T cells from young and old mice  Academic Article
  • Patterns of immune reactivity in auto-immune murine strains .1. Cell-mediated immune-responses induced by h-2 identical and h-2 incompatible stimulator cells  Academic Article
  • Patterns of responding differentiate intravenous nicotine self-administration from responding for a visual stimulus in C57BL/6J mice  Academic Article
  • Paucity of V-D-D-J rearrangements and V-H replacement events in lupus prone and nonautoimmune TdT(-/-) and TdT(+/+) mice  Academic Article
  • Peanut agglutinin high phenotype of activated cd8(+) t cells results from de novo synthesis of cd45 glycans  Academic Article
  • Pejvakin, a candidate stereociliary rootlet protein, regulates hair cell function in a cell-autonomous manner  Academic Article
  • Peptide nanofibers preconditioned with stem cell secretome are renoprotective  Academic Article
  • Peptide vaccination of mice immune to LCMV or vaccinia virus causes serious CD8 T cell-mediated, TNF-dependent immunopathology  Academic Article
  • Peptide-mediated activation of Akt and extracellular regulated kinase signaling prevents lymphocyte apoptosis  Academic Article
  • Peptidergic regulation of plasminogen activator inhibitor-1 gene expression in vivo  Academic Article
  • Peptidomics approach to elucidate the proteolytic regulation of bioactive peptides  Academic Article
  • Peptidomics of prolyl endopeptidase in the central nervous system  Academic Article
  • Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus  Academic Article
  • Peptidylarginine deiminase inhibition reduces vascular damage and modulates innate immune responses in murine models of atherosclerosis  Academic Article
  • Peptidylariginine deiminases: novel drug targets for prevention of neuronal damage following hypoxic ischemic insult (HI) in neonates  Academic Article
  • Periodontal dysbiosis linked to periodontitis is associated with cardiometabolic adaptation to high-fat diet in mice  Academic Article
  • Peripheral B cell tolerance and function in transgenic mice expressing an IgD superantigen  Academic Article
  • Peripheral deletion of CD8 T cells requires p38 MAPK in cross-presenting dendritic cells  Academic Article
  • Peripheral reduction of beta-amyloid is sufficient to reduce brain beta-amyloid: Implications for alzheimer's disease  Academic Article
  • Perm1 enhances mitochondrial biogenesis, oxidative capacity, and fatigue resistance in adult skeletal muscle  Academic Article
  • Peroxisome proliferator-activated receptor γ coactivator 1α and FoxO3A mediate chondroprotection by AMP-activated protein kinase  Academic Article
  • Persistent LCMV infection is controlled by blockade of type I interferon signaling  Academic Article
  • Persistent histamine excitation of glutamatergic preoptic neurons  Academic Article
  • Persistent macrophage/microglial activation and myelin disruption after experimental autoimmune encephalomyelitis in tissue inhibitor of metalloproteinase-1-deficient mice  Academic Article
  • Persistent virus infection inhibits type i interferon production by plasmacytoid dendritic cells to facilitate opportunistic infections  Academic Article
  • Pharmacokinetics and efficacy of the spleen tyrosine kinase inhibitor r406 after ocular delivery for retinoblastoma  Academic Article
  • Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence  Academic Article
  • Pharmacological activity of fatty acid amides is regulated, but not mediated, by fatty acid amide hydrolase in vivo  Academic Article
  • Pharmacological and behavioral profile of N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-6-chinolincarboxamide (EVP-5141), a novel α7 nicotinic acetylcholine receptor agonist/serotonin 5-HT3 receptor antagonist  Academic Article
  • Pharmacological and genetic modulation of REV-ERB activity and expression affects orexigenic gene expression  Academic Article
  • Pharmacological characterization of a novel α2C-adrenoceptor agonist N-[3,4-dihydro-4-(1H-imidazol-4-ylmethyl)-2H-1, 4-benzoxazin-6-yl]-N-ethyl-N'-methylurea (compound A)  Academic Article
  • Pharmacological characterization of a selective agonist for bombesin receptor subtype-3  Academic Article
  • Pharmacological selectivity within class I histone deacetylases predicts effects on synaptic function and memory rescue  Academic Article
  • Pharmacological studies of a new derivative of amphotericin-B, MS-8209, in mouse and hamster scrapie  Academic Article
  • Pharmacological targeting of the mammalian clock regulates sleep architecture and emotional behaviour  Academic Article
  • Pharmacological targeting of the thrombomodulin-activated protein c pathway mitigates radiation toxicity  Academic Article
  • Phasic D1 and tonic D2 dopamine receptor signaling double dissociate the motivational effects of acute nicotine and chronic nicotine withdrawal  Academic Article
  • Phenotype, function, and in vivo migration and survival of allogeneic dendritic cell progenitors genetically engineered to express TGF-beta  Academic Article
  • Phenotypic analysis of GalR2 knockout mice in anxiety- and depression-related behavioral tests  Academic Article
  • Phenotypic characterization of a genetically diverse panel of mice for behavioral despair and anxiety  Academic Article
  • Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia  Academic Article
  • Phospholipase Cγ2 is essential in the functions of B cell and several Fc receptors  Academic Article
  • Phosphorylation of the AMPA receptor GluR1 subunit is required for synaptic plasticity and retention of spatial memory  Academic Article
  • Phylogenetic variation and polymorphism at the toll-like receptor 4 locus (TLR4)  Academic Article
  • Physical and functional interaction between protocadherin 15 and myosin VIIa in mechanosensory hair cells  Academic Article
  • Physical association of histocompatibility antigens and tumor-associated antigens on the surface of murine lymphoma-cells  Academic Article
  • Physiological and behavioral effects of methamphetamine in a mouse model of endotoxemia: a preliminary study  Academic Article
  • Piezo1 in smooth muscle cells is involved in hypertension-dependent arterial remodeling  Academic Article
  • Plasma cells negatively regulate the follicular helper t cell program  Academic Article
  • Plasma membrane vesicles decorated with glycolipid-anchored antigens and adjuvants via protein transfer as an antigen delivery platform for inhibition of tumor growth  Academic Article
  • Plasma-derived MHC class II+ exosomes from tumor-bearing mice suppress tumor antigen-specific immune responses  Academic Article
  • Plasmid DNA encoding human carcinoembryonic antigen (cea) adsorbed onto cationic microparticles induces protective immunity against colon cancer in cea-transgenic mice  Academic Article
  • Plasminogen activator inhibitor-1 and its cofactor vitronectin stabilize arterial thrombi after vascular injury in mice  Academic Article
  • Plasminogen activator inhibitor-1 is a major stress-regulated gene: Implications for stress-induced thrombosis in aged individuals  Academic Article
  • Plasminogen has a broad extrahepatic distributions  Academic Article
  • Plasmodium circumsporozoite protein promotes the development of the liver stages of the parasite  Academic Article
  • Platelet glycoprotein Ib alpha supports experimental lung metastasis  Academic Article
  • Platelet hyperreactivity explains the bleeding abnormality and macrothrombocytopenia in a murine model of sitosterolemia  Academic Article
  • Platelet, not endothelial, p-selectin is required for neointimal formation after vascular injury  Academic Article
  • Platelets adhere to and translocate on von Willebrand factor presented by endothelium in simulated veins  Academic Article
  • Platelets and platelet adhesion support angiogenesis while preventing excessive hemorrhage  Academic Article
  • Platelets mediate cytotoxic T lymphocyte-induced liver damage  Academic Article
  • Platelets prevent IFN-α/β-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus  Academic Article
  • Pluripotin combined with leukemia inhibitory factor greatly promotes the derivation of embryonic stem cell lines from refractory strains  Academic Article
  • Point mutation in the glycoprotein of lymphocytic choriomeningitis virus is necessary for receptor binding, dendritic cell infection, and long-term persistence  Academic Article
  • Point mutations in the melanocortin-4 receptor cause variable obesity in mice  Academic Article
  • Polyclonality and multispecificity of the CTL response to a single viral epitope  Academic Article
  • Polymorphism within a tcrav family influences the repertoire through class i/ii restriction  Academic Article
  • Positional cloning of Lps, and the general role of toll-like receptors in the innate immune response  Academic Article
  • Positive modulation of ampa receptors increases neurotrophin expression by hippocampal and cortical neurons  Academic Article
  • Positive regulation of ltk ph domain function by soluble ip(4)  Academic Article
  • Post-translational changes to PrP alter transmissible spongiform encephalopathy strain properties  Academic Article
  • Posttranscriptional clearance of hepatitis B virus RNA by cytotoxic T lymphocyte-activated hepatocytes  Academic Article
  • Posttranslational modification of alpha-dystroglycan, the cellular receptor for arenaviruses, by the glycosyltransferase large is critical for virus binding  Academic Article
  • Posttranslational regulation of tcr v alpha allelic exclusion during t cell differentiation  Academic Article
  • Potent antitumor effects mediated by local expression of the mature form of the interferon-gamma inducing factor, interleukin-18 (IL-18)  Academic Article
  • Potential of small molecule-mediated reprogramming of rod photoreceptors to treat retinitis pigmentosa  Academic Article
  • Potential role for padi-mediated histone citrullination in preimplantation development  Academic Article
  • Preclinical evaluation of an anti-HCV miRNA cluster for treatment of HCV infection  Academic Article
  • Preclinical metabolic changes in mouse prion diseases detected by 1H-nuclear magnetic resonance spectroscopy  Academic Article
  • Precursor frequency, nonlinear proliferation, and functional maturation of virus-specific CD4(+) T cells  Academic Article
  • Precursor thymocyte proliferation and differentiation are controlled by signals unrelated to the pre-TCR  Academic Article
  • Preferential activation of an IL-2 regulatory sequence transgene in TCR gamma delta and NKT cells: subset-specific differences in IL-2 regulation  Academic Article
  • Preliminary PET study of F-18-FC119S in normal and Alzheimer's disease models  Academic Article
  • Prenatal diethylstilbestrol induces malformation of the external genitalia of male and female mice and persistent second-generation developmental abnormalities of the external genitalia in two mouse strains  Academic Article
  • Preparation of functionally active [35S] leptin for mapping its receptors in the brain  Academic Article
  • Presynaptic crf(1) receptors mediate the ethanol enhancement of gabaergic transmission in the mouse central amygdala  Academic Article
  • Presynaptic delta opioid receptors regulate ethanol actions in central amygdala  Academic Article
  • Pretreatment with phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibitor SF1670 augments the efficacy of granulocyte transfusion in a clinically relevant mouse model  Academic Article
  • Primary cilia regulate proliferation of amplifying progenitors in adult hippocampus: Implications for learning and memory  Academic Article
  • Primary demyelination in transgenic mice expressing interferon-gamma  Academic Article
  • Primary in vitro antibody responses by purified murine B lymphocytes in serum-free defined medium  Academic Article
  • Priming with endotoxin increases acute lung injury in mice by enhancing the severity of lung endothelial injury  Academic Article
  • Principles of cytotoxic T lymphocyte induction and recognition  Academic Article
  • Prion strain discrimination based on rapid in vivo amplification and analysis by the cell panel assay  Academic Article
  • Prion strain discrimination in cell culture: The cell panel assay  Academic Article
  • Prion strain discrimination using luminescent conjugated polymers  Academic Article
  • Prion transmission prevented by modifying the beta 2-alpha 2 loop structure of host PrP(C)  Academic Article
  • Prion-induced amyloid heart disease with high blood infectivity in transgenic mice  Academic Article
  • Probability of phenotypically detectable protein damage by ENU-induced mutations in the Mutagenetix database  Academic Article
  • Progesterone receptor-mediated up-regulation of transthyretin in preimplantation mouse uterus  Academic Article
  • Progression of activity and structural changes in the anterior cingulate cortex during remote memory formation  Academic Article
  • Progressive accumulation of amyloid-beta oligomers in Alzheimer's disease and in amyloid precursor protein transgenic mice is accompanied by selective alterations in synaptic scaffold proteins  Academic Article
  • Proliferative defects and formation of a double cortex in mice lacking Mltt4 and Cdh2 in the dorsal telencephalon  Academic Article
  • Prolongation of cardiac allograft survival using dendritic cells treated with NF-kappa B decoy oligodeoxyribonucleotides  Academic Article
  • Prolonged and effective blockade of tumor necrosis factor activity through adenovirus-mediated gene transfer  Academic Article
  • Prolonged exposure to sphingosine 1-phosphate receptor-1 agonists exacerbates vascular leak, fibrosis, and mortality after lung injury  Academic Article
  • Prolonged monoacylglycerol lipase blockade causes equivalent cannabinoid receptor type 1 receptor-mediated adaptations in fatty acid amide hydrolase wild-type and knockout mice  Academic Article
  • Prolonged systemic expression of human IL-1 receptor antagonist (hIL-1ra) in mice reconstituted with hematopoietic-cells transduced with a retrovirus carrying the hIL-1ra cDNA  Academic Article
  • Pronociceptive role of dynorphins in uninjured animals: N-ethylmaleimide-induced nociceptive behavior mediated through inhibition of dynorphin degradation  Academic Article
  • Propagation of rml prions in mice expressing prp devoid of gpi anchor leads to formation of a novel, stable prion strain  Academic Article
  • Propensity of adult lymphoid progenitors to progress to DN2/3 stage thymocytes with notch receptor ligation  Academic Article
  • Protease-activated receptor (par) 2, but not par1, signaling promotes the development of mammary adenocarcinoma in polyoma middle t mice  Academic Article
  • Protease-activated receptor-1 modulates hippocampal memory formation and synaptic plasticity  Academic Article
  • Protease-activated receptor-1 signaling by activated protein c in cytokine-perturbed endothelial cells is distinct from thrombin signaling  Academic Article
  • Protection against atherosclerosis by estrogen is independent of plasma cholesterol levels in ldl receptor-deficient mice  Academic Article
  • Protection against dengue disease by synthetic nucleic acid antibody prophylaxis/immunotherapy  Academic Article
  • Protection from cyanide-induced brain injury by the Nrf2 transcriptional activator carnosic acid  Academic Article
  • Protection of the intestinal mucosa by intraepithelial gamma delta T cells  Academic Article
  • Protection of vascular barrier integrity by activated protein C in murine models depends on protease-activated receptor-1  Academic Article
  • Protective immunity against human carcinoembryonic antigen (cea) induced by an oral DNA vaccine in cea-transgenic mice  Academic Article
  • Protein 4.1B expression is induced in mammary epithelial cells during pregnancy and regulates their proliferation  Academic Article
  • Protein 4.1B suppresses prostate cancer progression and metastasis  Academic Article
  • Protein S confers neuronal protection during ischemic/hypoxic injury in mice  Academic Article
  • Protein S is inducible by interleukin 4 in T cells and inhibits lymphoid cell procoagulant activity  Academic Article
  • Protein S protects neurons from excitotoxic injury by activating the TAM receptor Tyro3-phosphatidylinositol 3-kinase-Akt pathway through its sex hormone-binding globulin-like region  Academic Article
  • Protein carbamylation links inflammation, smoking, uremia and atherogenesis  Academic Article
  • Protein kinase C η is required for T cell activation and homeostatic proliferation  Academic Article
  • Protein kinase C-eta controls CTLA-4-mediated regulatory T cell function  Academic Article
  • Protein tyrosine phosphatase 1B regulates pyruvate kinase M2 tyrosine phosphorylation  Academic Article
  • Proteolytic cleavage of a self-antigen following xenobiotic-induced cell death produces a fragment with novel immunogenic properties  Academic Article
  • Proteome-wide quantification and characterization of oxidation-sensitive cysteines in pathogenic bacteria  Academic Article
  • Prp expression in b lymphocytes is not required for prion neuroinvasion  Academic Article
  • Pseudomonas aeruginosa outer-membrane protein f epitopes are highly immunogenic in mice when expressed an a plant virus  Academic Article
  • Pten mutations alter brain growth trajectory and allocation of cell types through elevated β-catenin signaling  Academic Article
  • Pulmonary surfactant proteins a and d directly suppress cd3(+)/cd4(+) cell function: Evidence for two shared mechanisms(1)  Academic Article
  • Pulsed azidohomoalanine labeling in mammals (PALM) detects changes in liver-specific LKB1 knockout mice  Academic Article
  • Purification of a benzo[a]pyrene binding protein by affinity chromatography and photoaffinity labeling  Academic Article
  • Qualitative and quantitative requirements for CD4(+) T cell-mediated antiviral protection  Academic Article
  • Quantitative and functional interrogation of parent-of-origin allelic expression biases in the brain  Academic Article
  • Quantitative and qualitative analyses of the immune responses induced by a multivalent minigene DNA vaccine  Academic Article
  • Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice  Academic Article
  • Quantitative in vivo and ex vivo confocal microscopy analysis of corneal cystine crystals in the Ctns(-/-) knockout mouse  Academic Article
  • Quantitative polymerase chain-reaction analysis reveals marked overexpression of interleukin-1-beta, interleukin-10 and interferon-gamma messenger-RNA in the lymph-nodes of lupus-prone mice  Academic Article
  • Quantitative reduction of the TCR adapter protein SLP-76 unbalances immunity and immune regulation  Academic Article
  • Quantitative trait loci mapping for cholesterol gallstones in akr/j and c57l/j strains of mice  Academic Article
  • R7BP complexes with RGS9-2 and RGS7 in the striatum differentially control motor learning and locomotor responses to cocaine  Academic Article
  • R7BP modulates opiate analgesia and tolerance but not withdrawal  Academic Article
  • RGS expression rate-limits recovery of rod photoresponses  Academic Article
  • RGS6/G beta 5 complex accelerates IKaCh gating kinetics in atrial myocytes and modulates parasympathetic regulation of heart rate  Academic Article
  • RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis  Academic Article
  • Rapamycin relieves lentiviral vector transduction resistance in human and mouse hematopoietic stem cells  Academic Article
  • Rapid activation of astrocyte-specific expression of gfap-lacz transgene by focal injury  Academic Article
  • Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition  Academic Article
  • Rapid antibody responses by low-dose, single-step, dendritic cell-targeted immunization  Academic Article
  • Rapid generation of potent and tumor-specific cytotoxic T lymphocytes by interleukin 18 using dendritic cells and natural killer cells  Academic Article
  • Rapid identification of a disease allele in mouse through whole genome sequencing and bulk segregation analysis  Academic Article
  • Ras pathway inhibition prevents neovascularization by repressing endothelial cell sprouting  Academic Article
  • Re-evaluating the in vivo cytokine responses of CD8+ T cells during primary and secondary viral infections  Academic Article
  • Reactivity of steroid-resistant neonatal thymocytes  Academic Article
  • Real-time differential labeling of blood, interstitium, and lymphatic and single-field analysis of vasculature dynamics in vivo  Academic Article
  • Rearrangement of mouse immunoglobulin kappa deleting element recombining sequence promotes immune tolerance and lambda B cell production  Academic Article
  • Recapitulation of ivig anti-inflammatory activity with a recombinant igg fc  Academic Article
  • Receptor editing and marginal zone b cell development are regulated by the helix-loop-helix protein, e2a  Academic Article
  • Receptor for advanced glycation end-products (RAGE) is an indicator of direct lung injury in models of experimental lung injury  Academic Article
  • Receptor subtype-dependent galanin actions on gamma-aminobutyric acidergic neurotransmission and ethanol responses in the central amygdala  Academic Article
  • Reciprocal expression in cd4 or cd8 subsets of different members of the v alpha 11 gene family correlates with sequence polymorphism  Academic Article
  • Recognition of bacterial glycosphingolipids by natural killer T cells  Academic Article
  • Recognition of conformational determinants on H-2 by cytolytic T lymphocytes  Academic Article
  • Recognition of influenza-infected cells by cytolytic T lymphocyte clones: determinant selection by class I restriction elements  Academic Article
  • Recombinant adenovirus induces maturation of dendritic cells via an NF-kappa B-dependent pathway  Academic Article
  • Recombinant murine-activated protein C is neuroprotective in a murine ischemic stroke model  Academic Article
  • Recombination of retrotransposon and exogenous RNA virus results in nonretroviral cDNA integration  Academic Article
  • Recruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in mice  Academic Article
  • Redirecting effector T cells through their IL-2 receptors  Academic Article
  • Reduced anxiety-like and cognitive performance in mice lacking the corticotropin-releasing factor receptor 1  Academic Article
  • Reduced cholesterol and triglycerides in mice with a mutation in mia2, a liver protein that localizes to er exit sites  Academic Article
  • Reduced expression of the NMDA receptor-interacting protein SynGAP causes behavioral abnormalities that model symptoms of schizophrenia  Academic Article
  • Reduced nnos expression induced by repeated nicotine treatment in mu-opioid receptor knockout mice  Academic Article
  • Reduced wheel running and blunted effects of voluntary exercise in LPA(1)-null mice: The importance of assessing the amount of running in transgenic mice studies  Academic Article
  • Regenerative phenotype in mice with a point mutation in transforming growth factor β type I receptor (TGFBR1)  Academic Article
  • Regulation of alpha-synuclein expression in limbic and motor brain regions of morphine-treated mice  Academic Article
  • Regulation of angiogenesis by tissue factor cytoplasmic domain signaling  Academic Article
  • Regulation of carbohydrate metabolism by the farnesoid x receptor  Academic Article
  • Regulation of cell division cycle progression by bcl-2 expression: A potential mechanism for inhibition of programmed cell death  Academic Article
  • Regulation of circadian behaviour and metabolism by REV-ERB-alpha and REV-ERB-beta  Academic Article
  • Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists  Academic Article
  • Regulation of expression of citrate synthase by the retinoic acid receptor-related orphan receptor alpha (ror alpha)  Academic Article
  • Regulation of feeding by galnon  Academic Article
  • Regulation of hepcidin transcription by interleukin-1 and interleukin-6  Academic Article
  • Regulation of inflammatory pain by inhibition of fatty acid amide hydrolase  Academic Article
  • Regulation of macrophage migration by a novel plasminogen receptor Plg-R(KT)  Academic Article
  • Regulation of murine type 1 plasminogen activator inhibitor gene expression in vivo. Tissue specificity and induction by lipopolysaccharide, tumor necrosis factor-alpha, and transforming growth factor-beta  Academic Article
  • Regulation of osteoclast differentiation and function by the CaMK-CREB pathway  Academic Article
  • Regulation of pyruvate dehydrogenase kinase expression by the farnesoid x receptor  Academic Article
  • Regulation of the B cell receptor repertoire and self-reactivity by BAFF  Academic Article
  • Regulation of thymus size by competition for stromal niches among early T cell progenitors  Academic Article
  • Regulation of tissue factor gene expression in obesity  Academic Article
  • Relationship of brain-derived neurotrophic factor and its receptor TrkB to altered inhibitory prefrontal circuitry in schizophrenia  Academic Article
  • Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific cd8(+) t cells  Academic Article
  • Repeated low-dose administration of the monoacylglycerol lipase inhibitor JZL184 retains cannabinoid receptor type 1-mediated antinociceptive and gastroprotective effects  Academic Article
  • Repertoire-based selection into the marginal zone compartment during B cell development  Academic Article
  • Replacing reprogramming factors with antibodies selected from combinatorial antibody libraries  Academic Article
  • Replication of dengue and junin viruses in cultured rabbit and human endothelial cells  Academic Article
  • Reprogramming of antiviral t cells prevents inactivation and restores t cell activity during persistent viral infection  Academic Article
  • Reprogramming pancreatic stellate cells via p53 activation: A putative target for pancreatic cancer therapy  Academic Article
  • Requirement for the lPA1 lysophosphatidic acid receptor gene in normal suckling behavior  Academic Article
  • Resisting viral infection: the gene by gene approach  Academic Article
  • Response and recovery in the plasma metabolome tracks the acute LCMV-induced immune response  Academic Article
  • Responses of endothelial cell and astrocyte matrix-integrin receptors to ischemia mimic those observed in the neurovascular unit  Academic Article
  • Responses of microRNAs 124a and 223 following spinal cord injury in mice  Academic Article
  • Restricted feeding-induced sleep, activity, and body temperature changes in normal and preproghrelin-deficient mice  Academic Article
  • Restricted v-segment usage in t-cell receptors from cytotoxic lymphocytes-t specific for a major epitope of lymphocytic choriomeningitis virus  Academic Article
  • Retinal TrkB receptors regulate neural development in the inner, but not outer, retina  Academic Article
  • Retroviral induction of acute lymphoproliferative disease and profound immunosuppression in adult C57BL/6 mice  Academic Article
  • Retrovirus-mediated transfer of viral IL-10 gene prolongs murine cardiac allograft survival  Academic Article
  • Rev-erb regulation of cholesterologenesis  Academic Article
  • Reversal of obesity and insulin resistance by a non-peptidic glucagon-like peptide-1 receptor agonist in diet-induced obese mice  Academic Article
  • Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: evidence for an unprecedented combination of potency and selectivity  Academic Article
  • Rhes deletion is neuroprotective in the 3-nitropropionic acid model of Huntington's disease  Academic Article
  • Ribosome stalling induced by mutation of a CNS-specific tRNA causes neurodegeneration  Academic Article
  • Role of astroglia in Down's syndrome revealed by patient-derived human-induced pluripotent stem cells  Academic Article
  • Role of cyclin kinase inhibitor p21 in systemic autoimmunity  Academic Article
  • Role of endocannabinoids in alcohol consumption and intoxication: Studies of mice lacking fatty acid amide hydrolase  Academic Article
  • Role of galanin receptor 1 and galanin receptor 2 activation in synaptic plasticity associated with 3 ',5 '-cyclic amp response element-binding protein phosphorylation in the dentate gyrus: Studies with a galanin receptor 2 agonist and galanin receptor 1 knockout mice  Academic Article
  • Role of gut macrophages in mice orally contaminated with scrapie or BSE  Academic Article
  • Role of immunoproteasome catalytic subunits in the immune response to hepatitis B virus  Academic Article
  • Role of leukocyte-specific ldl receptors on plasma lipoprotein cholesterol and atherosclerosis in mice  Academic Article
  • Role of par2 in murine pulmonary pseudomonal infection  Academic Article
  • Role of passive and adaptive immunity in influencing enterocyte-specific gene expression  Academic Article
  • Role of peroxiredoxin-2 in protecting rbcs from hydrogen peroxide-induced oxidative stress  Academic Article
  • Role of protease activated receptor 1 and 2 signaling in hypoxia-induced angiogenesis  Academic Article
  • Role of the corticotropin-releasing factor receptor type 2 in the control of food intake in mice: A meal pattern analysis  Academic Article
  • Role of the postnatal radial glial scaffold for the development of the dentate gyrus as revealed by reelin signaling mutant mice  Academic Article
  • Role of tumor necrosis factor alpha in induction of murine CD14 gene expression by lipopolysaccharide  Academic Article
  • Ror alpha coordinates reciprocal signaling in cerebellar development through sonic hedgehog and calcium-dependent pathways  Academic Article
  • Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs  Academic Article
  • Ryanodine receptor-2 upregulation and nicotine-mediated plasticity  Academic Article
  • S-adenosyl-L-homocysteine hydrolase inactivation curtails ovalbumin-induced immune responses  Academic Article
  • S-nitrosylation of matrix metalloproteinases: Signaling pathway to neuronal cell death  Academic Article
  • S1P activates store-operated calcium entry via receptor- and non-receptor-mediated pathways in vascular smooth muscle cells  Academic Article
  • S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species  Academic Article
  • SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation  Academic Article
  • SRC-1 null mice exhibit moderate motor dysfunction and delayed development of cerebellar Purkinje cells  Academic Article
  • SREBP1 contributes to resolution of pro-inflammatory TLR4 signaling by reprogramming fatty acid metabolism  Academic Article
  • SUMOylation of MeCP2 is essential for transcriptional repression and hippocampal synapse development  Academic Article
  • Scrapie-induced defects in learning and memory of transgenic mice expressing anchorless prion protein are associated with alterations in the gamma aminobutyric acid-ergic pathway  Academic Article
  • Secreted human glycyl-tRNA synthetase implicated in defense against ERK-activated tumorigenesis  Academic Article
  • Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival  Academic Article
  • Selection against puma gene expression in myc-driven b-cell lymphomagenesis  Academic Article
  • Selection of distinct populations of dentate granule cells in response to inputs as a mechanism for pattern separation in mice  Academic Article
  • Selection of tcr v-alpha by mhc class-ii predicts superantigen reactivity  Academic Article
  • Selective N-hydroxyhydantoin carbamate inhibitors of mammalian serine hydrolases  Academic Article
  • Selective and brain penetrant neuropeptide y y2 receptor antagonists discovered by whole-cell high-throughput screening  Academic Article
  • Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects  Academic Article
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  • Selective stimulation of t cell subsets with antibody-cytokine immune complexes  Academic Article
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  • Sepsis induces extensive autophagic vacuolization in hepatocytes: a clinical and laboratory-based study  Academic Article
  • Sequence and fine specificity analysis of primary 511 anti-phosphorylcholine antibodies  Academic Article
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  • Serial backcross mapping of multiple loci associated with resistance to leishmania major in mice  Academic Article
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  • Serotonin reciprocally regulates melanocortin neurons to modulate food intake  Academic Article
  • Serotonin, but not N-methyltryptamines, activates the serotonin 2A receptor via a beta-arrestin2/Src/Akt signaling complex in vivo  Academic Article
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  • Severe retinal degeneration caused by a novel rhodopsin mutation  Academic Article
  • Sex separation induces differences in the olfactory sensory receptor repertoires of male and female mice  Academic Article
  • Sex- and age-specific differences in core body temperature of C57Bl/6 mice  Academic Article
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  • Soluble cd14-mediated cellular responses to lipopolysaccharide  Academic Article
  • Soluble transferrin receptor-1 levels in mice do not affect iron absorption  Academic Article
  • Spatial mapping of thymic stromal microenvironments reveals unique features influencing T lymphoid differentiation  Academic Article
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  • Sperm-associated antigen-17 gene is essential for motile cilia function and neonatal survival  Academic Article
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  • The endogenous cannabinoid system protects against colonic inflammation  Academic Article
  • The endogenous lipid oleamide activates serotonin 5-HT7 neurons in mouse thalamus and hypothalamus  Academic Article
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  • The extracellular entrance provides selectivity to serotonin 5-HT7 receptor antagonists with antidepressant-like behavior in vivo  Academic Article
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  • The high degree of sequence plasticity of the arenavirus noncoding intergenic region (IGR) enables the use of a nonviral universal synthetic IGR to attenuate arenaviruses  Academic Article
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  • The induction of cytolytic T lymphocytes with purified plasma membranes  Academic Article
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  • The junctional adhesion molecule JAML is a costimulatory receptor for epithelial gamma delta T cell activation  Academic Article
  • The lymphopenic environment of CD132 (common gamma-chain)-deficient hosts elicits rapid homeostatic proliferation of naive T cells via IL-15  Academic Article
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  • The lysophosphatidic acid receptor lpa(1) promotes epithelial cell apoptosis after lung injury  Academic Article
  • The mGluR5 antagonist MPEP suppresses the expression and reinstatement, but not the acquisition, of the ethanol-conditioned place preference in mice  Academic Article
  • The major histocompatibility complex requirement for cellular collaboration in the murine lymphoid procoagulant response stimulated by bacterial lipopolysaccharide  Academic Article
  • The mammalian Doublesex homolog DMRT6 coordinates the transition between mitotic and meiotic developmental programs during spermatogenesis  Academic Article
  • The melanocortin-3 receptor is required for entrainment to meal intake  Academic Article
  • The methylenetetrahydrofolate reductase (Mthfr) gene maps to distal mouse chromosome 4  Academic Article
  • The monoacylglycerol lipase inhibitor JZL184 suppresses inflammatory pain in the mouse carrageenan model  Academic Article
  • The mouse CD1d-restricted repertoire is dominated by a few autoreactive T cell receptor families  Academic Article
  • The mouse lP(A3)/Edg7 lysophosphatidic acid receptor gene: Genomic structure, chromosomal localization, and expression pattern  Academic Article
  • The mouse supt16h/fact140 gene, encoding part of the fact chromatin transcription complex, maps close to tcra and is highly expressed in thymus  Academic Article
  • The neuropeptide galanin modulates behavioral and neurochemical signs of opiate withdrawal  Academic Article
  • The novel selective PDE9 inhibitor BAY 73-6691 improves learning and memory in rodents  Academic Article
  • The ontogeny of thymic independent antibody responses in vitro in normal mice and mice with an X-linked B cell defect  Academic Article
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  • The origin and function of soluble cd14 in experimental bacterial meningitis  Academic Article
  • The origin of strain-specific differences in the specificity repertoires of murine cytolytic T lymphocytes  Academic Article
  • The phospholipase A(2) inhibitor methyl indoxam suppresses diet-induced obesity and glucose intolerance in mice  Academic Article
  • The postmortal accumulation of brain N-arachidonylethanolamine (anandamide) is dependent upon fatty acid amide hydrolase activity  Academic Article
  • The potential dual effects of anesthetic isoflurane on Aβ-induced apoptosis  Academic Article
  • The preproghrelin gene is required for the normal integration of thermoregulation and sleep in mice  Academic Article
  • The proliferative potential of hematopoietic stem cells (CFUs) during serial passage in irradiated mice as foci of ectopic hematopoiesis [Article in Russian]  Academic Article
  • The prototypic Th2 autoimmunity induced by mercury is dependent on IFN-gamma and not Th1/Th2 imbalance  Academic Article
  • The putative endocannabinoid transport blocker LY2183240 is a potent inhibitor of FAAH and several other brain serine hydrolases  Academic Article
  • The rapidity with which virus-specific CD8+ T cells initiate IFN-γ synthesis increases markedly over the course of infection and correlates with immunodominance  Academic Article
  • The recognition of H-2 and viral antigens by cytotoxic T cells  Academic Article
  • The regulation of retina specific expression of rhodopsin gene in vertebrates  Academic Article
  • The role of BH3-only protein Bim extends beyond inhibiting Bcl-2-like prosurvival proteins  Academic Article
  • The role of IFN regulatory factor-1 in synovitis and nitric oxide production  Academic Article
  • The role of IFN-gamma in the production of Th2 subpopulations: implications for variable Th2-mediated pathologies in autoimmunity  Academic Article
  • The role of alpha beta(+) T cells and homeostatic T cell proliferation in Y-chromosome-associated murine lupus  Academic Article
  • The role of b lymphocytes in coxsackievirus b3 infection  Academic Article
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  • The role of cd8(+) t-lymphocytes in coxsackievirus b3-induced myocarditis  Academic Article
  • The role of surface IgD in the response to thymic-independent antigens  Academic Article
  • The role of vldlr in intraretinal angiogenesis in mice  Academic Article
  • The search for Lps: 1993-1998  Academic Article
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  • The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors  Academic Article
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  • The sphingosine-1-phosphate (S1P) lysophospholipid receptor S1P3 regulates MAdCAM-1+ endothelial cells in splenic marginal sinus organization  Academic Article
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  • The tissue factor pathway mediates both activation of coagulation and coagulopathy after injury  Academic Article
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  • The transcription factor Foxp1 is a critical negative regulator of the differentiation of follicular helper T cells  Academic Article
  • The transcriptional coactivators, PGC-1α and β, cooperate to maintain cardiac mitochondrial function during the early stages of insulin resistance  Academic Article
  • The transcriptional repressor STRA13 regulates a subset of peripheral circadian outputs  Academic Article
  • The tropomodulin (Tmod) gene maps to chromosome 4, closely linked to Mup1  Academic Article
  • The tyrosine kinase inhibitor gefitinib restricts mycobacterium tuberculosis growth through increased lysosomal biogenesis and modulation of cytokine signaling  Academic Article
  • The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosis  Academic Article
  • The unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via toll-like receptors 3, 7 and 9  Academic Article
  • The unfolded protein response mediates adaptation to exercise in skeletal muscle through a PGC-1α /ATF6α complex  Academic Article
  • The use of HLA A2.1/p53 peptide tetramers to visualize the impact of self tolerance on the TCR repertoire  Academic Article
  • The use of small molecule probes to study spatially separated stimulus-induced signaling pathways  Academic Article
  • The vomeronasal organ mediates interspecies defensive behaviors through detection of protein pheromone homologs  Academic Article
  • Themis sets the signal threshold for positive and negative selection in T-cell development  Academic Article
  • Therapeutic and specific antitumor immunity induced by co-administration of immature dendritic cells and adenoviral vector expressing biologically active IL-18  Academic Article
  • Therapeutic effect of exosomes from indoleamine 2,3-dioxygenase-positive dendritic cells in collagen-induced arthritis and delayed-type hypersensitivity disease models  Academic Article
  • Therapeutic efficacy of tumor-targeted il2 in lt alpha(-/-) mice depends on conditioned t cells  Academic Article
  • Three-dimensional in vivo imaging of the mouse intraocular vasculature during development and disease  Academic Article
  • Thrombin-dependent intravascular leukocyte trafficking regulated by fibrin and the platelet receptors GPIb and PAR4  Academic Article
  • Thymic cortical epithelium is sufficient for the development of mature t cells in relb-deficient mice  Academic Article
  • Thymic selection and adaptability of cytotoxic t-lymphocyte responses in transgenic mice expressing a viral protein in the thymus  Academic Article
  • Thymic selection and cell-division  Academic Article
  • Thymic selection by a single mhc/peptide ligand produces a semidiverse repertoire of cd4(+) t cells  Academic Article
  • Thymic selection by a single mhc/peptide ligand: Autoreactive t cells are low-affinity cells  Academic Article
  • Thymic skewing of the cd4/cd8 ratio maps with the t-cell receptor alpha-chain locus  Academic Article
  • Thymic t cell development and progenitor localization depend on ccr7  Academic Article
  • Thymocyte expression of cathepsin L is essential for NKT cell development  Academic Article
  • Thymocyte resistance to glucocorticoids leads to antigen-specific unresponsiveness due to "holes" in the t cell repertoire  Academic Article
  • Thymocyte stimulation by anti-tcr-beta, but not by anti-tcr-alpha, leads to induction of developmental transcription program  Academic Article
  • Tid1 is required for T cell transition from double-negative 3 to double-positive stages  Academic Article
  • Tid1, a cochaperone of the heat shock 70 protein and the mammalian counterpart of the Drosophila tumor suppressor 1(2)tid, is critical for early embryonic development and cell survival  Academic Article
  • Time course of morphine's effects on adult hippocampal subgranular zone reveals preferential inhibition of cells in S phase of the cell cycle and a subpopulation of immature neurons  Academic Article
  • Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression  Academic Article
  • Time-restricted feeding is a preventative and therapeutic intervention against diverse nutritional challenges  Academic Article
  • Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet  Academic Article
  • Tissue distribution and regulation of murine von Willebrand factor gene expression in vivo  Academic Article
  • Tissue distribution and regulation of plasminogen activator inhibitor-1 in obese mice  Academic Article
  • Tissue distribution of factor VIII gene expression in vivo: a closer look  Academic Article
  • Tissue factor expression during human and mouse development  Academic Article
  • Tissue factor gene expression in the adipose tissues of obese mice  Academic Article
  • Tissue factor prothrombotic activity is regulated by integrin-arf6 trafficking  Academic Article
  • Tissue factor-protease-activated receptor 2 signaling promotes diet-induced obesity and adipose inflammation  Academic Article
  • Tissue neogenesis and STRO-1 expression in immature and mature articular cartilage  Academic Article
  • Tissue plasminogen activator (tPA) deficiency exacerbates cerebrovascular fibrin deposition and brain injury in a murine stroke model - studies in tPA-deficient mice and wild-type mice on a matched genetic background  Academic Article
  • Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice  Academic Article
  • Tissue plasminogen activator neurovascular toxicity is controlled by activated protein C  Academic Article
  • Tissue- and epitope-specific mechanisms account for the diverse effects of anti-CD44 antibodies on the maintenance of primitive hematopoietic progenitors in vitro  Academic Article
  • Tissue-infiltrating neutrophils constitute the major in vivo source of angiogenesis-inducing MMP-9 in the tumor microenvironment  Academic Article
  • Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization  Academic Article
  • Tissue-specific regulation of p38α-mediated inflammation in Con A-induced acute liver damage  Academic Article
  • Tlr2 is constitutively expressed within the kidney and participates in ischemic renal injury through both myd88-dependent and -independent pathways  Academic Article
  • Tlr2 signaling subpathways regulate tlr9 signaling for the effective induction of il-12 upon stimulation by heat-killed brucella abortus  Academic Article
  • Tmod1 and CP49 synergize to control the fiber cell geometry, transparency, and mechanical stiffness of the mouse lens  Academic Article
  • Toll-like receptor 4 functions intracellularly in human coronary artery endothelial cells: Roles of lbp and scd14 in mediating lps-responses  Academic Article
  • Toll-like receptor 7 is required for effective adaptive immune responses that prevent persistent virus infection  Academic Article
  • Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection  Academic Article
  • Toll-like receptors in atherosclerosis  Academic Article
  • Topical treatment of basal cell carcinomas in nevoid basal cell carcinoma syndrome with a Smoothened inhibitor  Academic Article
  • Topically applied human recombinant monoclonal igg(1) antibody and its fab and f(ab')(2) fragments protect mice from vaginal transmission of hsv-2  Academic Article
  • Topography of thalamic projections requires attractive and repulsive functions of Netrin-1 in the ventral telencephalon  Academic Article
  • Towards understanding the schizophrenia code: an expanded convergent functional genomics approach  Academic Article
  • Tracking brain palmitoylation change: predominance of glial change in a mouse model of Huntington's disease  Academic Article
  • Transcription factor PU.1 is necessary for development of thymic and myeloid progenitor-derived dendritic cells  Academic Article
  • Transcriptional code and disease map for adult retinal cell types  Academic Article
  • Transcriptional control of preadipocyte determination by Zfp423  Academic Article
  • Transcriptional programs of lymphoid tissue capillary and high endothelium reveal control mechanisms for lymphocyte homing  Academic Article
  • Transduction of a marker gene (Neor) into precursor cells of the hematopoietic microenvironment [Article in Russian]  Academic Article
  • Transduction of dendritic cells with Bcl-xL increases their resistance to prostate cancer-induced apoptosis and antitumor effect in mice  Academic Article
  • Transfer of a prion strain to different hosts leads to emergence of strain variants  Academic Article
  • Transfer of dysbiotic gut microbiota has beneficial effects on host liver metabolism  Academic Article
  • Transgene-driven expression of the doppel protein in purkinje cells causes purkinje cell degeneration and motor impairment  Academic Article
  • Transgenic calmodulin-dependent protein kinase ii activation: Dose-dependent effects on synaptic plasticity, learning, and memory  Academic Article
  • Transgenic mice expressing human hla and cd8 molecules generate hla-restricted measles virus cytotoxic t lymphocytes of the same specificity as humans with natural measles virus infection  Academic Article
  • Transgenic mice with a reduced core body temperature have an increased life span  Academic Article
  • Transgenic overexpression of interleukin-1 receptor antagonist in the CNS influences behaviour, serum corticosterone and brain monoamines  Academic Article
  • Transglutaminase 2 is central to induction of the arterial calcification program by smooth muscle cells  Academic Article
  • Translational suppression of atrophic regulators by microRNA-23a integrates resistance to skeletal muscle atrophy  Academic Article
  • Transmission of the BSE agent to mice in the absence of detectable abnormal prion protein  Academic Article
  • Transnuclear mice with predefined T cell receptor specificities against Toxoplasma gondii obtained via SCNT  Academic Article
  • Transplant-induced reactivation of murine cytomegalovirus immediate early gene expression is associated with recruitment of NF-κB and AP-1 to the major immediate early promoter  Academic Article
  • Transplantation of virally transduced cells into the dermis of immunocompetent and immunodeficient (SCID) mice to determine gene expression profile and differential donor cell survival  Academic Article
  • Treatment of hind limb ischemia using angiogenic peptide nanofibers  Academic Article
  • Treatment of murine cerebral malaria by artemisone in combination with conventional antimalarial drugs: antiplasmodial effects and immune responses  Academic Article
  • Treatment of severe hypercholesterolemia in apolipoprotein e-deficient mice by bone-marrow transplantation  Academic Article
  • Treatment with HMGB1 inhibitors diminishes CTL-induced liver disease in HBV transgenic mice  Academic Article
  • Treatment with a sphingosine analog does not alter the outcome of a persistent virus infection  Academic Article
  • Trif is not required for immune complex glomerulonephritis: Dying cells activate mesangial cells via tlr2/myd88 rather than tlr3/trif  Academic Article
  • Tristetraprolin impairs myc-induced lymphoma and abolishes the malignant state  Academic Article
  • TrkB receptor controls striatal formation by regulating the number of newborn striatal neurons  Academic Article
  • Tropomodulin 1 directly controls thin filament length in both wild-type and tropomodulin 4-deficient skeletal muscle  Academic Article
  • Tumor necrosis factor alpha and interleukin 1 alpha induce anchorage independence in v-jun transgenic murine cells  Academic Article
  • Tumor necrosis factor inhibitor ameliorates murine intestinal graft-versus-host disease  Academic Article
  • Tumor-necrosis-factor-alpha and interleukin-1-alpha enhance glucose-utilization by astrocytes - involvement of phospholipase a(2)  Academic Article
  • Tuning of natural killer cell reactivity by NKp46 and Helios calibrates T cell responses  Academic Article
  • Two distinct but overlapping antibody binding sites in the pre-S(2) region of HBsAg localized within 11 continuous residues  Academic Article
  • Two subsets of epithelial cells in the thymic medulla  Academic Article
  • Twofold overexpression of human beta-amyloid precursor proteins in transgenic mice does not affect the neuromotor, cognitive, or neurodegenerative sequelae following experimental brain injury  Academic Article
  • Type 1 plasminogen activator inhibitor gene expression following partial hepatectomy  Academic Article
  • Type C botulinum toxin causes degeneration of motoneurons in vivo  Academic Article
  • Type I and type II interferon coordinately regulate suppressive dendritic cell fate and function during viral persistence  Academic Article
  • Type I interferon is a therapeutic target for virus-induced lethal vascular damage  Academic Article
  • Type I interferon suppresses de novo virus-specific CD4 Th1 immunity during an established persistent viral infection  Academic Article
  • UNC93B1 mediates host resistance to infection with Toxoplasma gondii  Academic Article
  • Ubiquitin-dependent control of class II MHC localization is dispensable for antigen presentation and antibody production  Academic Article
  • Ultrastructural localization of cellular prion protein (prpc) at the neuromuscular junction  Academic Article
  • Unacylated ghrelin rapidly modulates lipogenic and insulin signaling pathway gene expression in metabolically active tissues of GHSR deleted mice  Academic Article
  • Unc93b1 biases toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against rna-sensing  Academic Article
  • Unexpected autoantibody production in membrane ig-mu-deficient/lpr mice  Academic Article
  • Unifying model for molecular determinants of the preselection Vβ repertoire  Academic Article
  • Unique drug screening approach for prion diseases identifies tacrolimus and astemizole as antiprion agents  Academic Article
  • Unique haploinsufficient role of the microRNA-processing molecule Dicer1 in a murine colitis-associated tumorigenesis model  Academic Article
  • Unique uterine localization and regulation may differentiate LPA3 from other lysophospholipid receptors for its role in embryo implantation  Academic Article
  • Unrestricted recognition of a nonpeptide antigen by CD8+ cytolytic T lymphocytes  Academic Article
  • Up-regulation of surface-markers on dying thymocytes  Academic Article
  • Upregulation of fibronectin and the α5β1 and αvβ3 integrins on blood vessels within the cerebral ischemic penumbra  Academic Article
  • Upregulation of the Rab27a-dependent trafficking and secretory mechanisms improves lysosomal transport, alleviates endoplasmic reticulum stress, and reduces lysosome overload in cystinosis  Academic Article
  • Urocortin-deficient mice show hearing impairment and increased anxiety-like behavior  Academic Article
  • Urokinase-type plasminogen activator plays a critical role in angiotensin II-induced abdominal aortic aneurysm  Academic Article
  • Use of a dense single nucleotide polymorphism map for in silico mapping in the mouse  Academic Article
  • Use of a high-affinity peptide that aborts mhc-restricted cytotoxic t lymphocyte activity against multiple viruses in vitro and virus-induced immunopathologic disease in vivo  Academic Article
  • Use of multifunctional sigma-2 receptor ligand conjugates to trigger cancer-selective cell death signaling  Academic Article
  • Using injectoporation to deliver genes to mechanosensory hair cells  Academic Article
  • Using recombinant coxsackievirus b3 to evaluate the induction and protective efficacy of cd8(+) t cells during picornavirus infection  Academic Article
  • V alpha 3.2 selection in mhc class i mutant mice - evidence for an alternate orientation of tcr-mhc class i interaction  Academic Article
  • V-beta gene repertoires in t-cells expanded in local self-healing and lethal systemic murine cutaneous leishmaniasis  Academic Article
  • VBP15, a novel anti-inflammatory, is effective at reducing the severity of murine experimental autoimmune encephalomyelitis  Academic Article
  • VLDL hydrolysis by hepatic lipase regulates PPARδ transcriptional responses  Academic Article
  • VTA CRF neurons mediate the aversive effects of nicotine withdrawal and promote intake escalation  Academic Article
  • Vaccination and protection from a lethal viral infection: identification, incorporation, and use of a cytotoxic T lymphocyte glycoprotein epitope  Academic Article
  • Vaccination protects beta(2) microglobulin deficient mice from immune mediated mortality but not from persisting viral infection  Academic Article
  • Vascular endothelial growth factor receptor 2-based DNA immunization delays development of herpetic stromal keratitis by antiangiogenic effects  Academic Article
  • Velvet, a dominant egfr mutation that causes wavy hair and defective eyelid development in mice  Academic Article
  • Versatile strategy for controlling the specificity and activity of engineered T cells  Academic Article
  • Vesicular stomatitis virus glycoprotein g activates a specific antiviral toll-like receptor 4-dependent pathway  Academic Article
  • Vesicular trafficking through cortical actin during exocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase-activating protein Gem-interacting protein  Academic Article
  • Viral IL-10 gene transfer inhibits DTH responses to soluble antigens: Evidence for involvement of genetically modified dendritic cells and macrophages  Academic Article
  • Viral cross talk: Intracellular inactivation of the hepatitis B virus during an unrelated viral infection of the liver  Academic Article
  • Viral infection of transgenic mice expressing a viral protein in oligodendrocytes leads to chronic central nervous system autoimmune disease  Academic Article
  • Viral interleukin-10 (IL-10), the human herpes-virus-4 cellular IL-10 homolog, induces local anergy to allogeneic and syngeneic tumors  Academic Article
  • Viral nanoparticles associate with regions of inflammation and blood brain barrier disruption during CNS infection  Academic Article
  • Viral rna induces type i interferon-dependent cytokine release and cell death in mesangial cells via melanoma-differentiation-associated gene-5 implications for viral infection-associated glomerulonephritis  Academic Article
  • Viral targeting of hematopoietic progenitors and inhibition of dc maturation as a dual strategy for immune subversion  Academic Article
  • Virus specificity of cytotoxic T lymphocytes generated during acute lymphocytic choriomeningitis virus infection: role of the H-2 region in determining cross-reactivity for different lymphocytic choriomeningitis virus strains  Academic Article
  • Virus-induced immune complex disease: genetic control of C1q binding complexes in the circulation of mice persistently infected with lymphocytic choriomeningitis virus  Academic Article
  • Virus-induced immunosuppression .1. Age at infection relates to a selective or generalized defect  Academic Article
  • Visualization of the genesis and fate of isotype-switched b cells during a primary immune response  Academic Article
  • Visualizing cold spots: TRPM8-expressing sensory neurons and their projections  Academic Article
  • Visualizing the viral burden: Phenotypic and functional alterations of t cells and apcs during persistent infection  Academic Article
  • Vitronectin gene expression in vivo. Evidence for extrahepatic synthesis and acute phase regulation  Academic Article
  • Voronoi binding site model of a polycyclic aromatic hydrocarbon binding protein  Academic Article
  • Weight-loss in obese mice persistently infected with lymphocytic choriomeningitis virus is not associated with elevated tumor necrosis factor cachectin activity in peritoneal-macrophages  Academic Article
  • Whole-body physiologically based pharmacokinetic model for nutlin-3a in mice after intravenous and oral administration  Academic Article
  • Widespread and stable pancreatic gene transfer by adeno-associated virus vectors via different routes  Academic Article
  • Wild-type coxsackievirus infection dramatically alters the abundance, heterogeneity, and immunostimulatory capacity of conventional dendritic cells in vivo  Academic Article
  • Wiring and molecular features of prefrontal ensembles representing distinct experiences  Academic Article
  • X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C  Academic Article
  • Xenobiotic acceleration of idiopathic systemic autoimmunity in lupus-prone BXSB mice  Academic Article
  • ZBTB1 is a determinant of lymphoid development  Academic Article
  • Zika virus infection during the period of maximal brain growth causes microcephaly and corticospinal neuron apoptosis in wild type mice  Academic Article
  • betaCaMKII in lateral habenula mediates core symptoms of depression  Academic Article
  • delta BAFF, a splice isoform of BAFF, opposes full-length BAFF activity in vivo in transgenic mouse models  Academic Article
  • mu-Opioid receptors mediate the effects of chronic ethanol binge drinking on the hippocampal neurogenic niche  Academic Article
  • rAAV9 combined with renal vein injection is optimal for kidney-targeted gene delivery: conclusion of a comparative study  Academic Article
  • Δ9-tetrahydrocannabinol and endocannabinoid degradative enzyme inhibitors attenuate intracranial self-stimulation in mice  Academic Article
  • α8-integrins are required for hippocampal long-term potentiation but not for hippocampal-dependent learning  Academic Article
  • β-Amyloid exacerbates inflammation in astrocytes lacking fatty acid amide hydrolase through a mechanism involving PPAR-α, PPAR-γ and TRPV1, but not CB₁ or CB₂ receptors  Academic Article

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