subject area of
- 1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) analogs of CC-1065 and the duocarmycins: synthesis and evaluation Academic Article
- 1,3,8-Triazaspiro[4.5]decane-2,4-diones as efficacious pan-inhibitors of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) for the treatment of anemia Academic Article
- 11-deoxy prostaglandin F(2 alpha), a thromboxane A2 receptor agonist, partially alleviates embryo crowding in Lpar3(-/-) females Academic Article
- 5-HT(1A) receptor mutant mice exhibit enhanced tonic, stress-induced and fluoxetine-induced serotonergic neurotransmission Academic Article
- 5-HT(7) receptor inhibition and inactivation induce antidepressantlike behavior and sleep pattern Academic Article
- 5-aminoimidazole-4-carboxyamide-ribonucleoside (AICAR)-stimulated hepatic expression of Cyp4a10, Cyp4a14, Cyp4a31, and other peroxisome proliferator-activated receptor alpha-responsive mouse genes is AICAR 5'-monophosphate-dependent and AMP-activated protein kinase-independent Academic Article
- A 3-dimensional extracellular matrix as a delivery system for the transplantation of glioma-targeting neural stem/progenitor cells Academic Article
- A 5' leader of Rbm3, a cold stress-induced mRNA, mediates internal initiation of translation with increased efficiency under conditions of mild hypothermia Academic Article
- A DNA vaccine against vegf receptor 2 prevents effective angiogenesis and inhibits tumor growth Academic Article
- A DNA vaccine targeting fos-related antigen 1 enhanced by il-18 induces long-lived t-cell memory against tumor recurrence Academic Article
- A DNA vaccine targeting survivin combines apoptosis with suppression of angiogenesis in lung tumor eradication Academic Article
- A Jekyll and Hyde profile: Type 1 interferon signaling plays a prominent role in the initiation and maintenance of a persistent virus infection Academic Article
- A ZAP-70 kinase domain variant prevents thymocyte- positive selection despite signalling CD69 induction Academic Article
- A catalytically inactive mutant of the deubiquitylase YOD-1 enhances antigen cross-presentation Academic Article
- A catechol-O-methyltransferase that is essential for auditory function in mice and humans Academic Article
- A chemically induced vaccine strategy for prostate cancer Academic Article
- A chimeric mouse model of Gaucher disease Academic Article
- A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol Academic Article
- A crucial role of mitochondrial Hsp40 in preventing dilated cardiomyopathy Academic Article
- A derivative of the melanocortin receptor antagonist shu9119 (pg932) increases food intake when administered peripherally Academic Article
- A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid use Academic Article
- A dominant-negative mutant of c-Jun inhibits cell cycle progression during the transition of CD4(-)CD8(-) to CD4(+) CD8(+) thymocytes Academic Article
- A dual role for microglia in promoting tissue inhibitor of metalloproteinase (timp) expression in glial cells in response to neuroinflammatory stimuli Academic Article
- A factor IX-deficient mouse model for hemophilia B gene therapy Academic Article
- A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function Academic Article
- A functional genomics strategy reveals Rora as a component of the mammalian circadian clock Academic Article
- A genetic determinant that specifically regulates the frequency of hematopoietic stem cells Academic Article
- A genetically encoded multifunctional TRAIL trimer facilitates cell-specific targeting and tumor cell killing Academic Article
- A gfp-equipped bidirectional expression module well suited for monitoring tetracycline-regulated gene expression in mouse Academic Article
- A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity Academic Article
- A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia Academic Article
- A keratinocyte-responsive gamma delta tcr is necessary for dendritic epidermal t cell activation by damaged keratinocytes and maintenance in the epidermis Academic Article
- A lack of mu-opioid receptors modulates the expressions of neuropeptide y and substance p mrna Academic Article
- A leukocyte homologue of the il-8 receptor cxcr-2 mediates the accumulation of macrophages in atherosclerotic lesions of ldl receptor-deficient mice Academic Article
- A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses Academic Article
- A major histocompatibility complex class I-dependent subset of memory phenotype CD8(+) cells Academic Article
- A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration Academic Article
- A mouse model of pemphigus vulgaris by adoptive transfer of naive splenocytes from desmoglein 3 knockout mice Academic Article
- A multivalent minigene vaccine, containing b-cell, cytotoxic t-lymphocyte, and t-h epitopes from several microbes, induces appropriate responses in vivo and confers protection against more than one pathogen Academic Article
- A mutant mouse with a highly specific contextual fear-conditioning deficit found in an N-ethyl-N-nitrosourea (ENU) mutagenesis screen Academic Article
- A new UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase mRNA exhibits predominant expression in the hypothalamus, thalamus and amygdala of mouse forebrain Academic Article
- A novel DNA vaccine encoding pdgfr beta suppresses growth and dissemination of murine colon, lung and breast carcinoma Academic Article
- A novel ELISA for mouse activated protein C in plasma Academic Article
- A novel allele of myosin viia reveals a critical function for the c-terminal ferm domain for melanosome transport in retinal pigment epithelial cells Academic Article
- A novel and simple method for culturing pericytes from mouse brain Academic Article
- A novel approach for in vivo measurement of mouse red cell redox status Academic Article
- A novel class II MHC molecule with unusual tissue distribution Academic Article
- A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol with potential anti-obesity effects Academic Article
- A novel function of p38-regulated/activated kinase in endothelial cell migration and tumor angiogenesis Academic Article
- A novel generation of heparan sulfate mimetics for the treatment of prion diseases Academic Article
- A novel method for analysis of nuclear receptor function at natural promoters: Peroxisome proliferator-activated receptor gamma agonist actions on ap2 gene expression detected using branched DNA messenger rna quantitation Academic Article
- A novel method to establish microglia-free astrocyte cultures: Comparison of matrix metalloproteinase expression profiles in pure cultures of astrocytes and microglia Academic Article
- A novel neuron-specific DNA end-binding factor in the murine brain Academic Article
- A novel non-transcriptional pathway mediates the proconvulsive effects of interleukin-1β Academic Article
- A novel transgenic mouse model for immunological evaluation of carcinoembryonic antigen-based DNA minigene vaccines Academic Article
- A novel, systemically active, selective galanin receptor type-3 ligand exhibits antidepressant-like activity in preclinical tests Academic Article
- A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects Academic Article
- A pathologic cascade leading to synaptic dysfunction in alpha-synuclein-induced neurodegeneration Academic Article
- A peptide that antagonizes tcr-mediated reactions with both syngeneic and allogeneic agonists: Functional and structural aspects Academic Article
- A peptidomics strategy to elucidate the proteolytic pathways that inactivate peptide hormones Academic Article
- A phenotype survey of 36 mutant mouse strains with gene-targeted defects in glycosyltransferases or glycan-binding proteins Academic Article
- A photo-cleavable biotin affinity tag for the facile release of a photo-crosslinked carbohydrate-binding protein Academic Article
- A pivotal role for the multifunctional calcium/calmodulin-dependent protein kinase ii in t cells: From activation to unresponsiveness Academic Article
- A point mutation in sec61 alpha 1 leads to diabetes and hepatosteatosis in mice Academic Article
- A point mutation in the amino terminus of TLR7 abolishes signaling without affecting ligand binding Academic Article
- A population of murine gamma delta T cells that recognize an inducible MHC class Ib molecule Academic Article
- A possible oligosaccharide-conjugate vaccine candidate for Clostridium difficile is antigenic and immunogenic Academic Article
- A potential role for adiponectin receptor 2 (AdipoR2) in the regulation of alcohol intake Academic Article
- A ppar gamma-lxr-abca1 pathway in macrophages is involved in cholesterol efflux and atherogenesis Academic Article
- A proapoptotic peptide for the treatment of solid tumors Academic Article
- A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions Academic Article
- A rabbit antiserum detects a vh j558 subgroup marker highly expressed among anti-alprenolol antibodies Academic Article
- A regenerative approach to the treatment of multiple sclerosis Academic Article
- A reversible S-adenosyl-L-homocysteine hydrolase inhibitor ameliorates experimental autoimmune encephalomyelitis by inhibiting T cell activation Academic Article
- A role for dual viral hits in causation of subacute sclerosing panencephalitis Academic Article
- A role for skin γδ T cells in wound repair Academic Article
- A role for tcr affinity in regulating naive t cell homeostasis Academic Article
- A role for the GIRK3 subunit in methamphetamine-induced aAttenuation of GABA(B) receptor-activated GIRK currents in VTA dopamine neurons Academic Article
- A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition Academic Article
- A role of the fast ATP-gated P2X(1) cation channel in thrombosis of small arteries in vivo Academic Article
- A secreted Slit2 fragment regulates adipose tissue thermogenesis and metabolic function Academic Article
- A semisynthetic carbohydrate-lipid vaccine that protects against S-pneumoniae in mice Academic Article
- A shared neural ensemble links distinct contextual memories encoded close in time Academic Article
- A spontaneous rheumatoid arthritis-like disease in mrl/1 mice Academic Article
- A spontaneously arising pancreatic tumor does not promote the differentiation of naive CD8+ T lymphocytes into effector CTL Academic Article
- A stress response pathway regulates DNA damage through beta(2)-adrenoreceptors and beta-arrestin-1 Academic Article
- A string-of-beads vaccine, comprising linked minigenes, confers protection from lethal-dose virus challenge Academic Article
- A structural hierarchy mediated by multiple nuclear factors establishes IgH locus conformation Academic Article
- A study of complexes of class II invariant chain peptide: major histocompatibility complex class II molecules using a new complex-specific monoclonal antibody Academic Article
- A substrate-free activity-based protein profiling screen for the discovery of selective PREPL inhibitors Academic Article
- A t-cell receptor-v-alpha region selectively expressed in cd4+ cells Academic Article
- A toll-like receptor 2-responsive lipid effector pathway protects mammals against skin infections with gram-positive bacteria Academic Article
- A transgenic mouse model for measles virus infection of the brain Academic Article
- A transgenic mouse model of the chronic hepatitis B surface antigen carrier state Academic Article
- A transgenic mouse model to assess the interaction of cytotoxic t-lymphocytes with virally infected, class-i mhc-expressing astrocytes Academic Article
- A v(h)11v(kappa)9b cell antigen receptor drives generation of cd5(+) b cells both in vivo and in vitro Academic Article
- A view from above: Cloud plots to visualize global metabolomic data Academic Article
- A viral epitope that mimics a self antigen can accelerate but nit initiate autoimmune diabetes Academic Article
- ABHD12 controls brain lysophosphatidylserine pathways that are deregulated in a murine model of the neurodegenerative disease PHARC Academic Article
- ABIN-1 protects against psoriasis by restricting MyD88 signals in dendritic cells Academic Article
- AMPAR-independent effect of striatal αCaMKII promotes the sensitization of cocaine reward Academic Article
- ASPP2 deficiency causes features of 1q41q42 microdeletion syndrome Academic Article
- ATP induces protein arginine deiminase 2-dependent citrullination in mast cells through the P2X7 purinergic receptor Academic Article
- ATP-sensitive potassium channel (K-ATP)-dependent regulation of cardiotropic viral infections Academic Article
- Aberrant development of the suprachiasmatic nucleus and circadian rhythms in mice lacking the homeodomain protein Six6 Academic Article
- Ablation of NG2 proteoglycan leads to deficits in brown fat function and to adult onset obesity Academic Article
- Ablation of cd22 in ligand-deficient mice restores b cell receptor signaling Academic Article
- Ablation of ghrelin improves the diabetic but not obese phenotype of ob/ob mice Academic Article
- Abnormalities of plasma cytokines and spleen in senile APP/PS1/Tau transgenic mouse model Academic Article
- Absence of CTL responses to early viral antigens facilitates viral persistence Academic Article
- Absence of LPA1 signaling results in defective cortical development Academic Article
- Absence of carbohydrate response element binding protein in adipocytes causes systemic insulin resistance and impairs glucose transport Academic Article
- Absence of the alpha v beta 3 integrin dictates the time-course of angiogenesis in the hypoxic central nervous system: Accelerated endothelial proliferation correlates with compensatory increases in alpha 5 beta 1 integrin expression Academic Article
- Absence of the lysophosphatidic acid receptor LPA1 results in abnormal bone development and decreased bone mass Academic Article
- Activated intrahepatic antigen-presenting cells inhibit hepatitis B virus replication in the liver of transgenic mice Academic Article
- Activated protein C analog promotes neurogenesis and improves neurological outcome after focal ischemic stroke in mice via protease activated receptor 1 Academic Article
- Activated protein C preserves functional islet mass after intraportal transplantation - a novel link between endothelial cell activation, thrombosis, inflammation, and islet cell death Academic Article
- Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3 Academic Article
- Activated protein C promotes neovascularization and neurogenesis in postischemic brain via protease-activated receptor 1 Academic Article
- Activated protein C targets CD8(+) dendritic cells to reduce the mortality of endotoxemia in mice Academic Article
- Activation kinetics and off-target effects of thymus-initiated cre transgenes Academic Article
- Activation of PPARdelta alters lipid metabolism in db/db mice Academic Article
- Activation of liver x receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue Academic Article
- Activation of lysophosphatidic acid receptor type 1 contributes to pathophysiology of spinal cord injury Academic Article
- Activation of multidrug resistance (P-glycoprotein) mdr3/mdr1a gene during the development of hepatocellular carcinoma in hepatitis B virus transgenic mice Academic Article
- Activation of murine cd4(+) and cd8(+) t lymphocytes leads to dramatic remodeling of n-linked glycans Academic Article
- Activation of preexisting t cell clones by targeted interleukin 2 therapy Academic Article
- Activation of the alpha7 nAChR reduces acid-induced acute lung injury in mice and rats Academic Article
- Activation of the alternative complement pathway by fetal calf serum and mouse thymocytes Academic Article
- Activation of the endocannabinoid system by organophosphorus nerve agents Academic Article
- Activation/division of lymphocytes results in increased levels of cytoplasmic activation/proliferation-associated protein-1: prototype of a new family of proteins Academic Article
- Activators of the nuclear receptor ppar gamma enhance colon polyp formation Academic Article
- Acute exposure to cxc chemokine ligand 10, but not its chronic astroglial production, alters synaptic plasticity in mouse hippocampal slices Academic Article
- Acylated and unacylated ghrelin impair skeletal muscle atrophy in mice Academic Article
- Adaptation of the bovine spongiform encephalopathy agent to primates and comparison with Creutzfeldt-- Jakob disease: implications for human health Academic Article
- Adenoviral delivery of CTLA4ig into myeloid dendritic cells promotes their in vitro tolerogenicity and survival in allogeneic recipients Academic Article
- Adenoviral-mediated, intratumor gene transfer of interleukin 23 induces a therapeutic antitumor response Academic Article
- Adenovirus serotype 5 fiber shaft influences in vivo gene transfer in mice Academic Article
- Adenovirus-mediated direct gene therapy with bone morphogenetic protein-2 produces bone Academic Article
- AdipoR1 and 2 are expressed on warm sensitive neurons of the hypothalamic preoptic area and contribute to central hyperthermic effects of adiponectin Academic Article
- Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARγ specifies lipid storage versus thermogenic gene programs Academic Article
- Adjuvant activity of the histamine-sensitizing factor of Bordetella pertussis in different strains of mice Academic Article
- Adjuvant therapy with agonistic antibodies to CD134 (OX40) increases local control after surgical or radiation therapy of cancer in mice Academic Article
- Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling Academic Article
- Administration of systemic or local interleukin-2 enhances the antitumor effects of interleukin-12 gene-therapy Academic Article
- Adoptive immunotherapy induces cns dendritic cell recruitment and antigen presentation during clearance of a persistent viral infection Academic Article
- Adoptive transfer of fluorescence-labeled cells shows that resident peritoneal-macrophages are able to migrate into specialized lymphoid organs and inflammatory sites in the mouse Academic Article
- Adropin deficiency is associated with increased adiposity and insulin resistance Academic Article
- Adult mice generated from induced pluripotent stem cells Academic Article
- Afamin secreted from nonresorbing osteoclasts acts as a chemokine for preosteoblasts via the Akt-signaling pathway Academic Article
- Age- and gender-specific changes of hypocretin immunopositive neurons in C57Bl/6 mice Academic Article
- Age-dependent loss of sperm production in mice via impaired tysophosphatidic acid signaling Academic Article
- Age-related effects of Ginkgo biloba extract on synaptic plasticity and excitability Academic Article
- Aged app23 mice show a delay in switching to the use of a strategy in the barnes maze Academic Article
- Aging accelerates endotoxin-induced thrombosis: increased responses of plasminogen activator inhibitor-1 and lipopolysaccharide signaling with aging Academic Article
- Aging leads to a programmed loss of brown adipocytes in murine subcutaneous white adipose tissue Academic Article
- Aging leads to disturbed homeostasis of memory phenotype cd8(+) cells Academic Article
- Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics Academic Article
- Allelic exclusion of mouse t-cell receptor-alpha chains occurs at the time of thymocyte tcr up-regulation Academic Article
- Allelic exclusion of the tcr alpha-chain is an active process requiring tcr-mediated signaling and c-cbl Academic Article
- Alloantibodies can discriminate class I major histocompatibility complex molecules associated with various endogenous peptides Academic Article
- Alloantigen-enhanced accumulation of CCR5+ 'effector' regulatory T cells in the gravid uterus Academic Article
- Allosteric activators of glucokinase: potential role in diabetes therapy Academic Article
- Alpha 8 integrin in glomerular mesangial cells and in experimental glomerulonephritis Academic Article
- Alterations in neural cell-adhesion molecules during development of different regions of the nervous-system Academic Article
- Alterations of endocannabinoid signaling, synaptic plasticity, learning, and memory in monoacylglycerol lipase knock-out mice Academic Article
- Altered activity-rest patterns in mice with a human autosomal-dominant nocturnal frontal lobe epilepsy mutation in the β2 nicotinic receptor Academic Article
- Altered central nervous system gene expression caused by congenitally acquired persistent infection with lymphocytic choriomeningitis virus Academic Article
- Altered functional and biochemical response by CD8+ T cells that remain after tolerance Academic Article
- Altered helper T lymphocyte function associated with chronic hepatitis B virus infection and its role in response to therapeutic vaccination in humans Academic Article
- Altered synaptic transmission in the hippocampus of transgenic mice with enhanced central nervous systems expression of interleukin-6 Academic Article
- Alternative mRNA splicing produces a novel biologically active short isoform of PGC-1 alpha Academic Article
- Alternatively spliced tissue factor induces angiogenesis through integrin ligation Academic Article
- Amelioration of chronic murine colitis by peptide-mediated transduction of the I kappa B kinase inhibitor NEMO binding domain peptide Academic Article
- Amisulpride is a potent 5-ht(7) antagonist: Relevance for antidepressant actions in vivo Academic Article
- Among cxcr3 chemokines, ifn-gamma-inducible protein of 10 kda (cxc chemokine ligand (cxcl) 10) but not monokine induced by ifn-gamma (cxcl9) imprints a pattern for the subsequent development of autoimmune disease Academic Article
- Amphotericin B increases influenza A virus infection by preventing IFITM3-mediated restriction Academic Article
- Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD Academic Article
- Amyloid and nonfibrillar deposits in mice transgenic for wild-type human transthyretin: A possible model for senile systemic amyloidosis Academic Article
- Amyloid deposition in the hippocampus and entorhinal cortex: Quantitative analysis of a transgenic mouse model Academic Article
- An IRF-3-, IRF-5-, and IRF-7-independent pathway of dengue viral resistance utilizes IRF-1 to stimulate type I and II interferon responses Academic Article
- An activated protein c analog with reduced anticoagulant activity extends the therapeutic window of tissue plasminogen activator for ischemic stroke in rodents Academic Article
- An active dominant mutation of glycyl-tRNA synthetase causes neuropathy in a Charcot-Marie-Tooth 2D mouse model Academic Article
- An activity-based imaging probe for the integral membrane hydrolase KIAA1363 Academic Article
- An ahemolytic pneumolysin of Streptococcus pneumoniae manipulates human innate and CD4⁺ T-cell responses and reduces resistance to colonization in mice in a serotype-independent manner Academic Article
- An analog of the natural steroidal alkaloid cortistatin A potently suppresses Tat-dependent HIV transcription Academic Article
- An angiogenic role for the alpha 5 beta 1 integrin in promoting endothelial cell proliferation during cerebral hypoxia Academic Article
- An anti-apoptotic peptide improves survival in lethal total body irradiation Academic Article
- An antibody-interleukin 2 fusion protein overcomes tumor heterogeneity by induction of a cellular immune response Academic Article
- An apolipoprotein e synthetic peptide targets to lipoproteins in plasma and mediates both cellular lipoprotein interactions in vitro and acute clearance of cholesterol-rich lipoproteins in vivo Academic Article
- An autologous oral DNA vaccine protects against murine melanoma Academic Article
- An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. II. Mammalian fibroblast cultures transformed by DNA and RNA tumor viruses Academic Article
- An essential role for Rxr alpha in the development of Th2 responses Academic Article
- An oral DNA vaccine against human carcinoembryonic antigen (cea) prevents growth and dissemination of lewis lung carcinoma in cea transgenic mice Academic Article
- Analysis of antigen-specific B-cell memory directly ex vivo Academic Article
- Analysis of central b cell tolerance in autoimmune-prone mrl/lpr mice bearing autoantibody transgenes Academic Article
- Analysis of individual immunoglobulin-lambda light-chain genes amplified from single cells is inconsistent with variable region gene conversion in germinal-center b-cell somatic mutation Academic Article
- Analysis of sphingosine 1-phosphate receptors involved in constriction of isolated cerebral arteries with receptor null mice and pharmacological tools Academic Article
- Analysis of the MCMV resistome by ENU mutagenesis Academic Article
- Analysis of the effect of estrogen/androgen perturbation on penile development in transgenic and diethylstilbestrol-Treated mice Academic Article
- Analysis of the proteolysis of bioactive peptides using a peptidomics approach Academic Article
- Analysis of the therapeutic functions of novel melanocortin receptor agonists in mc3r-and mc4r-deficient c57bl/6j mice Academic Article
- Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum Academic Article
- Anandamide-induced neuroblastoma cell rounding via the CB1 cannabinoid receptors Academic Article
- Anchorless prion protein results in infectious amyloid disease without clinical scrapie Academic Article
- Aneuploid cells are differentially susceptible to caspase-mediated death during embryonic cerebral cortical development Academic Article
- Angiomotin regulates endothelial cell migration during embryonic angiogenesis Academic Article
- Animal model of respiratory syncytial virus: CD8(+) T cells cause a cytokine storm that is chemically tractable by sphingosine-1-phosphate 1 receptor agonist therapy Academic Article
- Antagonism between MyD88- and TRIF-dependent signals in B7RP-1 up-regulation Academic Article
- Antagonizing peroxisome proliferator-activated receptor α activity selectively enhances Th1 immunity in male mice Academic Article
- Anti-Gag cytolytic T lymphocytes specific for an alternative translational reading frame-derived epitope and resistance versus susceptibility to retrovirus-induced murine AIDS in F(1) mice Academic Article
- Anti-IFN-alpha/beta receptor antibody treatment ameliorates disease in lupus-predisposed mice Academic Article
- Anti-OX40 stimulation in vivo enhances CD8(+) memory T cell survival and significantly increases recall responses Academic Article
- Anti-apoptotic peptides protect against radiation-induced cell death Academic Article
- Anti-cd11b antibody prevents immunopathologic changes in viable moth-eaten bone-marrow chimeric mice Academic Article
- Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones Academic Article
- Anti-inflammatory, antithrombotic, and neuroprotective effects of activated protein C in a murine model of focal ischemic stroke Academic Article
- Antibacterial effect of human mesenchymal stem cells is mediated in part from secretion of the antimicrobial peptide LL-37 Academic Article
- Antibiotic-induced microbiome depletion alters metabolic homeostasis by affecting gut signaling and colonic metabolism Academic Article
- Anticonvulsant activity of a nonpeptide galanin receptor agonist Academic Article
- Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation Academic Article
- Antidiabetic activity of a highly potent and selective nonpeptide somatostatin receptor subtype-2 agonist Academic Article
- Antigen delivery to macrophages using liposomal nanoparticles targeting sialoadhesin/cd169 Academic Article
- Antigen presentation in retroviral vector-mediated gene transfer in vivo Academic Article
- Antigen-driven B cell differentiation in vivo Academic Article
- Antigen-induced unresponsiveness results in altered t cell signaling Academic Article
- Antigen-specific b cell memory: Expression and replenishment of a novel b220(-) memory b cell compartment Academic Article
- Antigen-specific cytotoxicity by invariant NKT cells in vivo is CD95/CD178-dependent and is correlated with antigenic potency Academic Article
- Antigen-specific naive CD8(+) T cells produce a single pulse of IFN-gamma in vivo within hours of infection, but without antiviral effect Academic Article
- Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis Academic Article
- Antioxidant or neurotrophic factor treatment preserves function in a mouse model of neovascularization-associated oxidative stress Academic Article
- Antiphospholipid antibodies are directed against epitopes of oxidized phospholipids - recognition of cardiolipin by monoclonal antibodies to epitopes of oxidized low density lipoprotein Academic Article
- Antiplatelet drug therapy moderates immune-mediated liver disease and inhibits viral clearance in mice infected with a replication-deficient adenovirus Academic Article
- Antiproliferation activity of a small molecule repressor of liver receptor homolog 1 Academic Article
- Antipsychotic drug treatment alters expression of mrnas encoding lipid metabolism-related proteins Academic Article
- Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models Academic Article
- Anxiolytic-Like Effects of Antisauvagine-30 in Mice Are Not Mediated by CRF2 Receptors Academic Article
- ApoE4 decreases spine density and dendritic complexity in cortical neurons in vivo Academic Article
- Apoa1 reduces free cholesterol accumulation in atherosclerotic lesions of apoe-deficient mice transplanted with apoe-expressing macrophages Academic Article
- Architecture of cannabinoid signaling in mouse retina Academic Article
- Area specificity and topography of thalamocortical projections are controlled by ephrin/eph genes Academic Article
- Arenavirus genome rearrangement for the development of live attenuated vaccines Academic Article
- Arginine 54 and tyrosine 118 residues of αA-crystallin are crucial for lens formation and transparency Academic Article
- Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction Academic Article
- Arylsulfonamide kcn1 inhibits in vivo glioma growth and interferes with hif signaling by disrupting hif-1 alpha interaction with cofactors p300/cbp Academic Article
- Ascl1 defines sequentially generated lineage-restricted neuronal and oligodendrocyte precursor cells in the spinal cord Academic Article
- Assessing interactions between Ghsr and Mc3r reveals a role for AgRP in the expression of food anticipatory activity in male mice Academic Article
- Assessment of anandamide's pharmacological effects in mice deficient of both fatty acid amide hydrolase and cannabinoid CB1 receptors Academic Article
- Association of cartilage-specific deletion of peroxisome proliferator-activated receptor gamma with abnormal endochondral ossification and impaired cartilage growth and development in a murine model Academic Article
- Astrocyte hypoxic response is essential for pathological but not developmental angiogenesis of the retina Academic Article
- Astrocyte pVHL and HIF-alpha isoforms are required for embryonic-to-adult vascular transition in the eye Academic Article
- Astrocytes are the primary source of tissue factor in the murine central nervous system. A role for astrocytes in cerebral hemostasis Academic Article
- Astrocytes contribute to gamma oscillations and recognition memory Academic Article
- Atg5-independent autophagy regulates mitochondrial clearance and is essential for iPSC reprogramming Academic Article
- Atheroprotective potential of macrophage-derived phospholipid transfer protein in low-density lipoprotein receptor-deficient mice is overcome by apolipoprotein ai overexpression Academic Article
- Atherosclerosis in mice is not affected by a reduction in tissue factor expression Academic Article
- Attenuation of allergic contact dermatitis through the endocannabinoid system Academic Article
- Attenuation of experimental autoimmune hepatitis by exogenous and endogenous cannabinoids: Involvement of regulatory T cells Academic Article
- Aurora kinases a and b are up-regulated by myc and are essential for maintenance of the malignant state Academic Article
- Autocrine selection of a GLP-1R G-protein biased agonist with potent antidiabetic effects Academic Article
- Autoimmunity-associated LYP-W620 does not impair thymic negative selection of autoreactive T cells Academic Article
- Autologous regulation of naive t cell homeostasis within the t cell compartment Academic Article
- Automatic annotation of matrix-assisted laser desorption/ionization n-glycan spectra Academic Article
- Autophagy activation by rapamycin reduces severity of experimental osteoarthritis Academic Article
- Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis Academic Article
- Autotaxin and lysophosphatidic acid(1) receptor-mediated demyelination of dorsal root fibers by sciatic nerve injury and intrathecal lysophosphatidylcholine Academic Article
- Avidity of cd1d-ligand-receptor ternary complex contributes to t-helper 1 (th1) polarization and anticancer efficacy Academic Article
- Azetidine and piperidine carbamates as efficient, covalent inhibitors of monoacylglycerol lipase Academic Article
- B cell selection defects underlie the development of diabetogenic apcs in nonobese diabetic mice Academic Article
- B cells from knock-in mice expressing broadly neutralizing HIV antibody b12 carry an innocuous B cell receptor responsive to HIV vaccine candidates Academic Article
- B-cell development in mice that lack one or both immunoglobulin kappa-light chain genes Academic Article
- B7 expression on thymic medullary epithelium correlates with epithelium-mediated deletion of v-beta-5(+) thymocytes Academic Article
- B7-1/2, but not PD-L1/2 molecules, are required on IL-10-treated tolerogenic DC and DC-derived exosomes for in vivo function Academic Article
- BCR engagement induces Fas resistance in primary B cells in the absence of functional Bruton's tyrosine kinase Academic Article
- BDNF overexpression in the forebrain rescues Huntington's disease phenotypes in YAC128 mice Academic Article
- BDNF promotes differentiation and maturation of adult-born neurons through GABAergic transmission Academic Article
- BK channel β1 subunit contributes to behavioral adaptations elicited by chronic intermittent ethanol exposure Academic Article
- Bacopaside I ameliorates cognitive impairment in APP/PS1 mice via immune-mediated clearance of β-amyloid. Academic Article
- Barx2 is expressed in satellite cells and is required for normal muscle growth and regeneration Academic Article
- Basomedial amygdala mediates top-down control of anxiety and fear Academic Article
- Bax loss impairs myc-induced apoptosis and circumvents the selection of p53 mutations during myc-mediated lymphomagenesis Academic Article
- Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis Academic Article
- Bcr ligation induces receptor editing in igm(+)igd(-) bone marrow b cells in vitro Academic Article
- Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex Academic Article
- Behavioral and neural correlates of acute and scheduled hunger in C57BL/6 mice Academic Article
- Behavioral and neurochemical studies on brain aging in galanin overexpressing mice Academic Article
- Behavioral phenotype of maLPA1-null mice: Increased anxiety-like behavior and spatial memory deficits Academic Article
- Beta 1-integrins are required for hippocampal AMPA receptor-dependent synaptic transmission, synaptic plasticity, and working memory Academic Article
- Beta 2-microglobulin is required for the full expression of xenobiotic-induced systemic autoimmunity Academic Article
- Beta 8 integrin and band 4.1b cooperatively regulate morphogenesis of the embryonic heart Academic Article
- Beyond the 12/23 rule of VDJ recombination independent of the Rag proteins Academic Article
- Bim siRNA decreases lymphocyte apoptosis and improves survival in sepsis Academic Article
- Binding of thymus- and bone marrow-derived lymphoid cells to antigen-derivatized fibers Academic Article
- Biogenic amine synthesis and uptake in rodent taste buds Academic Article
- Bioinformatic analysis of circadian gene oscillation in mouse aorta Academic Article
- Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus. I. Generation and recognition of virus strains and H-2b mutants Academic Article
- Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus. V. Recognition is restricted to gene products encoded by the viral S RNA segment Academic Article
- Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus. VI. Migration and activity in vivo in acute and persistent infection Academic Article
- Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus: clearance of virus in vivo Academic Article
- Biomagnetic isolation of antigen-specific CD8(+) T cells usable in immunotherapy Academic Article
- Biphasic and cardiomyocyte-specific IFIT activity protects cardiomyocytes from enteroviral infection Academic Article
- Biphasic effect of melanocortin agonists on metabolic rate and body temperature Academic Article
- Bisphosphonates target B cells to enhance humoral immune responses Academic Article
- Bitopic sphingosine 1-phosphate receptor 3 (S1P3) antagonist rescue from complete heart block: pharmacological and genetic evidence for direct S1P3 regulation of mouse cardiac conduction Academic Article
- Blockade of 2-arachidonoylglycerol hydrolysis by selective monoacylglycerol lipase inhibitor 4-nitrophenyl 4-(dibenzo d 1,3 dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate (jzl184) enhances retrograde endocannabinoid signaling Academic Article
- Blockade of 2-arachidonoylglycerol hydrolysis produces antidepressant-like effects and enhances adult hippocampal neurogenesis and synaptic plasticity Academic Article
- Blockade of endocannabinoid hydrolytic enzymes attenuates precipitated opioid withdrawal symptoms in mice Academic Article
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