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Melanoma

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  • A genomic screen identifies TYRO3 as a MITF regulator in melanoma  Academic Article
  • A monoclonal-antibody recognizes an o-acylated sialic-acid in a human melanoma-associated ganglioside  Academic Article
  • A pRb-responsive, RGD-modified, and Hyaluronidase-armed Canine Oncolytic Adenovirus for Application in Veterinary Oncology  Academic Article
  • A phase i clinical trial of the hu14.18-il2 (emd 273063) as a treatment for children with refractory or recurrent neuroblastoma and melanoma: A study of the children's oncology group  Academic Article
  • A potent and specific immunotoxin for tumor-cells expressing disialoganglioside gd2  Academic Article
  • A prospective study of telomere length and the risk of skin cancer  Academic Article
  • Activity-based probes for the proteomic profiling of metalloproteases  Academic Article
  • Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics  Academic Article
  • Ammonium-chloride interferes with a distinct step in the biosynthesis and cell-surface expression of human melanoma-type chondroitin sulfate proteoglycan  Academic Article
  • An arg-gly-asp-directed receptor on the surface of human-melanoma cells exists in a divalent cation-dependent functional complex with the disialoganglioside gd2  Academic Article
  • Analysis of effector-cells in human antibody-dependent cellular cytotoxicity with murine monoclonal-antibodies  Academic Article
  • Antagonism of c-IAP and XIAP proteins is required for efficient induction of cell death by small-molecule IAP antagonists  Academic Article
  • Antibody conjugates with morpholinodoxorubicin and acid-cleavable linkers  Academic Article
  • Antibody responses in melanoma patients immunized with an anti-idiotype antibody mimicking disialoganglioside gd2  Academic Article
  • Antibody-interleukin 2 fusion proteins: A new approach to cancer therapy  Academic Article
  • Antibody-targeted interleukin-2 stimulates t-cell killing of autologous tumor-cells  Academic Article
  • Antigenic expression of human-melanoma cells in serum-free medium  Academic Article
  • Antinuclear, antinucleolar, and anticytoplasmic antibodies in patients with malignant melanoma  Academic Article
  • Approaches for isolation of biologically functional tumor-associated antigens  Academic Article
  • Biosynthesis and secretion of fibronectin in human-melanoma cells  Academic Article
  • CD4(+) T cells kill HLA-class-II-antigen-positive melanoma cells presenting peptide in vitro  Academic Article
  • Cell cycle dependent sensitivity of human melanoma cells to melphalan is correlated with the activity and cellular concentration of glutathione transferases  Academic Article
  • Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo  Academic Article
  • Characterization of monoclonal-antibody 155.8 and partial characterization of its proteoglycan antigen on human-melanoma cells  Academic Article
  • Characterization of two monoclonal antibodies against human tissue-type plasminogen activator  Academic Article
  • Chemical adaptor immunotherapy: design, synthesis, and evaluation of novel integrin-targeting devices  Academic Article
  • Clinical and immune responses in advanced melanoma patients immunized with an anti-idiotype antibody mimicking disialoganglioside gd2  Academic Article
  • Clinical significance of alpha(v)beta(3) integrin and intercellular adhesion molecule-1 expression in cutaneous malignant melanoma lesions  Academic Article
  • Colony-stimulating factor enhancement of myeloid effector cell cytotoxicity towards neuroectodermal tumor-cells  Academic Article
  • Comparative analysis of dendritic cells transduced with different anti-apoptotic molecules: sensitivity to tumor-induced apoptosis  Academic Article
  • Critical evaluation of bispecific antibodies as targetins agents for boron neutron capture therapy of brain tumors  Academic Article
  • DCAF4, a novel gene associated with leucocyte telomere length  Academic Article
  • Delineation of the peptide binding site of the human galanin receptor  Academic Article
  • Design and simulation of a neutron source based on an electron linear accelerator for bnct of skin melanoma  Academic Article
  • Detection of malignant melanoma with monoclonal antibodies  Academic Article
  • Differential antitumor effects of administration of recombinant IL-18 or recombinant IL-12 are mediated primarily by Fas-Fas ligand- and perforin-induced tumor apoptosis, respectively  Academic Article
  • Differential internalization of hu14.18-il2 immunocytokine by nk and tumor cell: Impact on conjugation, cytotoxicity, and targeting  Academic Article
  • Differential role of tissue factor pathway inhibitors 1 and 2 in melanoma vasculogenic mimicry  Academic Article
  • Discovery of potent competitive inhibitors of indoleamine 2,3-dioxygenase with in vivo pharmacodynamic activity and efficacy in a mouse melanoma model  Academic Article
  • Discriminating neoantigenic differences between fibrinogen and fibrin derivatives  Academic Article
  • Disialoganglioside gd3 on human-melanoma serves as a relevant target antigen for monoclonal antibody-mediated tumor cytolysis  Academic Article
  • Disruption of angiogenesis by pex, a noncatalytic metalloproteinase fragment with integrin binding activity  Academic Article
  • Disruption of matrix metalloproteinase 2 binding to integrin alpha(v)beta(3) by an organic molecule inhibits angiogenesis and tumor growth in vivo  Academic Article
  • Downregulation of tumor growth and invasion by redox-active nanoparticles  Academic Article
  • Doxorubicin conjugated with a monoclonal-antibody directed to a human melanoma-associated proteoglycan suppresses the growth of established tumor xenografts in nude-mice  Academic Article
  • Effect of tissue inhibitor of the matrix metalloproteinases-2 expression on the growth and spontaneous metastasis of a human-melanoma cell-line  Academic Article
  • Enzyme activity profiles of the secreted and membrane proteome that depict cancer cell invasiveness  Academic Article
  • Eradication of established human-melanoma tumors in nude-mice by antibody-directed effector-cells  Academic Article
  • Eradication of human hepatic and pulmonary melanoma metastases in scid mice by antibody-interleukin 2 fusion proteins  Academic Article
  • Expression of class Pi glutathione transferase in human malignant melanoma cells  Academic Article
  • Expression of histocompatibility (hla) antigens on tumor-cells and normal cells from patients with melanoma  Academic Article
  • Expression of tissue factor by melanoma-cells promotes efficient hematogenous metastasis  Academic Article
  • Fibroblast growth-factors in normal and malignant melanocytes  Academic Article
  • Fibroblasts genetically engineered to secrete interleukin 12 can suppress tumor growth and induce antitumor immunity to a murine melanoma in vivo  Academic Article
  • Fibronectin enhancement of directed migration of b-16 melanoma-cells  Academic Article
  • Full-length mrna-seq from single-cell levels of rna and individual circulating tumor cells  Academic Article
  • Galanin: a neuropeptide with inhibitory actions  Academic Article
  • Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests  Academic Article
  • Ganglioside gm2 as a human-tumor antigen (ofa-i-1)  Academic Article
  • Glutathione transferase P1-1 expression in human melanoma metastases: correlation to N-RAS mutations and expression  Academic Article
  • High frequency of neoplasia in patients with autoantibodies to centromere protein CENP-F  Academic Article
  • Human cytotoxic t-cells suppress the growth of spontaneous melanoma metastases in scid/hu mice  Academic Article
  • Human melanoma cells derived from lymphatic metastases use integrin alpha v beta 3 to adhere to lymph node vitronectin  Academic Article
  • Human melanoma-associated antigens - role of carbohydrate in shedding and cell-surface expression  Academic Article
  • Human neural cell adhesion molecule l1 and rat homologue nile are ligands for integrin alpha(v)beta(3)  Academic Article
  • Human tumor-associated antigens defined by monoclonal-antibodies  Academic Article
  • Human-melanoma antigen o-acetylated ganglioside-gd3 is recognized by cancer-antennarius lectin  Academic Article
  • Human-melanoma associated antigens - a solid-phase assay for detection of specific antibody  Academic Article
  • Human-tumor antigens  Academic Article
  • Humoral sensitization in parous women - cytotoxic antibodies to non hl-a antigens  Academic Article
  • IL-6 signals inhibition of cell adhesion in melanoma A375-C6  Academic Article
  • Imaging of tumor vascularization using fluorescence molecular tomography to monitor arginine deiminase treatment in melanoma  Academic Article
  • Immunochemical and biosynthetic analysis of monoclonal antibody-defined melanoma-associated antigen  Academic Article
  • Immunochemical characterization of human-tumor antigens  Academic Article
  • Immunochemical delineation of an oncofetal antigen on normal and simian-virus 40-transformed human-fetal melanocytes  Academic Article
  • Immunocytokines: A new approach to immunotherapy of melanoma  Academic Article
  • Immunocytokines: A promising approach to cancer immunotherapy  Academic Article
  • Immunologic effects of an orally available BRAFV600E inhibitor in BRAF wild-type murine models  Academic Article
  • Immunoradiometric assay to measure the binding of a specific inhibitor to tissue-type plasminogen activator  Academic Article
  • Increased lysis of melanoma by in vivo-elicited human lymphokine-activated killer cells after addition of antiganglioside antibodies in vitro  Academic Article
  • Indole-3-carbinol (I3C) analogues are potent small molecule inhibitors of NEDD4-1 ubiquitin ligase activity that disrupt proliferation of human melanoma cells  Academic Article
  • Induction of igg antibodies by an anti-idiotype antibody mimicking disialoganglioside gd2  Academic Article
  • Inflammatory cells in solid murine neoplasms. I. Tumor disaggregation and identification of constituent inflammatory cells  Academic Article
  • Inhibition of anchorage-independent growth of human-melanoma cells by a monoclonal-antibody to a chondroitin sulfate proteoglycan  Academic Article
  • Inhibition of cancer cell proliferation by designed peptide amphiphiles  Academic Article
  • Inhibition of post-translational modification and surface expression of a melanoma-associated chondroitin sulfate proteoglycan by diethylcarbamazine or ammonium chloride  Academic Article
  • Inhibition of the fibroblast growth-factor receptor 1 (fgfr-1) gene in human melanocytes and malignant melanomas leads to inhibition of proliferation and signs indicative of differentiation  Academic Article
  • Integrin-alpha(v)beta(3) rescues melanoma-cells from apoptosis in 3-dimensional dermal collagen  Academic Article
  • Interim analysis of oxicity and response in phase 1 trial of systemic targeted alpha therapy for metastatic melanoma  Academic Article
  • Interleukin 12 gene therapy of cancer by peritumoral injection of transduced autologous fibroblasts: Outcome of a phase I study  Academic Article
  • Interleukin-2: Developing additional cytokine gene therapies using fibroblasts or dendritic cells to enhance tumor immunity  Academic Article
  • Intralesional targeted alpha therapy for metastatic melanoma  Academic Article
  • Involvement of b lymphocytes in the growth inhibition of human pulmonary melanoma metastases in athymic nu/nu mice by in antibody-lymphotoxin fusion protein  Academic Article
  • Involvement of integrin alpha V gene expression in human melanoma tumorigenicity  Academic Article
  • Involvement of tumor cell integrin alpha v beta 3 in hematogenous metastasis of human melanoma cells  Academic Article
  • Isolation and immunochemical characterization of antibodies from the sera of cancer-patients which are reactive against human-melanoma cell-membranes by affinity chromatography  Academic Article
  • Isolation of a soluble tumor-associated antigen from human melanoma  Academic Article
  • Lack of association of serologically detectable human melanoma-associated antigens with beta2 microglobulin - serologic and immunochemical evidence  Academic Article
  • Limited genomic heterogeneity of circulating melanoma cells in advanced stage patients  Academic Article
  • Localization of the gangliosides gd2 and gd3 in adhesion plaques and on the surface of human-melanoma cells  Academic Article
  • Long-lived and transferable tumor immunity in mice after targeted interleukin-2 therapy  Academic Article
  • Lymphocyte-mediated alopecia in c57bl/6 mice following successful immunotherapy for melanoma  Academic Article
  • Lymphokine-activated killer-cells targeted by monoclonal-antibodies to the disialogangliosides gd2 and gd3 specifically lyse human-tumor cells of neuroectodermal origin  Academic Article
  • MDM4 is a key therapeutic target in cutaneous melanoma  Academic Article
  • Magnetic resonance imaging in choroidal tumors  Academic Article
  • Mechanisms of cellular cytotoxicity mediated by a recombinant antibody il2 fusion protein against human-melanoma cells  Academic Article
  • Melanoma-associated gangliosides in the fish genus Xiphophorus  Academic Article
  • Melanoma-mediated dissolution of extracellular-matrix - contribution of urokinase-dependent and metalloproteinase-dependent proteolytic pathways  Academic Article
  • Molecular cloning of a human melanoma-associated chondroitin sulfate proteoglycan  Academic Article
  • Molecular profiles of human melanoma-associated antigens  Academic Article
  • Monoclonal antibody and an antibody-toxin conjugate to a cell surface proteoglycan of melanoma cells suppress in vivo tumor growth  Academic Article
  • Monoclonal antibody-directed effector cells selectively lyse human melanoma cells in vitro and in vivo  Academic Article
  • Myelin-associated glycoprotein shares an antigenic determinant with a glycoprotein of human-melanoma cells  Academic Article
  • Nature of immune-complexes in human cancer sera  Academic Article
  • Negative transcriptional regulation in anergic t-cells  Academic Article
  • Noninvasive presurgical neuromagnetic mapping of somatosensory cortex  Academic Article
  • Novel mechanistic insights into arginine deiminase pharmacology suggest 18F-FDG is not suitable to evaluate clinical response in melanoma  Academic Article
  • O-acetylation of disialoganglioside-gd3 by human-melanoma cells creates a unique antigenic determinant  Academic Article
  • Palmitoylation-dependent activation of MC1R prevents melanomagenesis  Academic Article
  • Phage-display selection of a human single-chain fv antibody highly specific for melanoma and breast cancer cells using a chemoenzymatically synthesized G(M3)-carbohydrate antigen  Academic Article
  • Pharmacokinetics and mechanism of action of a doxorubicin-monoclonal antibody 9.2.27 conjugate directed to a human-melanoma proteoglycan  Academic Article
  • Phase i clinical trial of the immunocytokine emd 273063 in melanoma patients  Academic Article
  • Phase ib trial of chimeric antidisialoganglioside antibody plus interleukin 2 for melanoma patients  Academic Article
  • Phenotypic knockout of VEGF-R2 and Tie-2 with an intradiabody reduces tumor growth and angiogenesis in vivo  Academic Article
  • Phosphatidylinositol 3,4,5-trisphosphate activity probes for the labeling and proteomic characterization of protein binding partners  Academic Article
  • Platelet glycoprotein Ib alpha supports experimental lung metastasis  Academic Article
  • Preclinical evaluation in nonhuman primates of murine monoclonal anti-idiotype antibody that mimics the disialoganglioside gd2  Academic Article
  • Production and characterization of monoclonal-antibody to a melanoma specific glycoprotein  Academic Article
  • Protease-activated receptors (par1 and par2) contribute to tumor cell motility and metastasis  Academic Article
  • Purification and immunological evaluation of human melanoma-associated antigens  Academic Article
  • Purification of soluble human melanoma-associated antigens  Academic Article
  • Radioimmunometric antibody-binding assay for evaluation of xenoantisera to melanoma-associated antigens  Academic Article
  • Rate of internalization of an immunotoxin correlates with cyto-toxic activity against human-tumor cells  Academic Article
  • Recombinant expression, biochemical-characterization, and biological-activities of the human MGSA-gro protein  Academic Article
  • Role of alpha V integrins and vitronectin in human melanoma cell growth  Academic Article
  • Role of beta 3 integrins in melanoma cell adhesion to activated platelets under flow  Academic Article
  • Sensitization of human melanoma cells to the cytotoxic effect of melphalan by the glutathione transferase inhibitor ethacrynic acid  Academic Article
  • Serological and biochemical analyses of monoclonal-antibodies to human melanoma-associated antigens  Academic Article
  • Serum half-life and tumor-localization of a chimeric antibody deleted of the ch2 domain and directed against the disialoganglioside-gd2  Academic Article
  • Signaling antibodies complexed with adenovirus circumvent car and integrin interactions and improve gene delivery  Academic Article
  • Small molecule drug activity in melanoma models may be dramatically enhanced with an antibody effector  Academic Article
  • Streptonigrin and lavendamycin partial structures - probes for the minimum, potent pharmacophore of streptonigrin, lavendamycin, and synthetic quinoline-5,8-diones  Academic Article
  • Suppression of spontaneous melanoma metastasis in scid mice with an antibody to the epidermal growth-factor receptor  Academic Article
  • Systemic interleukin-2 modulates the anti-idiotypic response to chimeric anti-gd2 antibody in patients with melanoma  Academic Article
  • TAT-Bim induces extensive apoptosis in cancer cells  Academic Article
  • Target cell-induced t-cell activation with bispecific and trispecific antibody fragments  Academic Article
  • Targeting heat shock proteins on cancer cells: Selection, characterization, and cell-penetrating properties of a peptidic GRP78 ligand  Academic Article
  • Targeting of t lymphocytes to melanoma cells through chimeric anti-gd3 immunoglobulin t-cell receptors  Academic Article
  • The antimalarial amodiaquine causes autophagic-lysosomal and proliferative blockade sensitizing human melanoma cells to starvation- and chemotherapy-induced cell death  Academic Article
  • The quinone methide aurin is a heat shock response inducer that causes proteotoxic stress and Noxa-dependent apoptosis in malignant melanoma cells  Academic Article
  • Therapeutic efficacy of a doxorubicin immunoconjugate in a preclinical model of spontaneous metastatic human-melanoma  Academic Article
  • Therapeutic potential of chimeric and murine anti-(epidermal growth-factor receptor) antibodies in a metastasis model for human-melanoma  Academic Article
  • Tissue factor-initiated thrombin generation activates the signaling thrombin receptor on malignant-melanoma cells  Academic Article
  • Transcriptional repression of IFN beta 1 by ATF2 confers melanoma resistance to therapy  Academic Article
  • Transforming growth factor-beta 1 increases survival of human melanoma through stroma remodeling  Academic Article
  • Tumor escape from immune recognition: lethal recurrent melanoma in a patient associated with downregulation of the peptide transporter protein TAP-1 and loss of expression of the immunodominant MART-1/Melan-A antigen  Academic Article
  • Tumor-associated antigens in spent medium of human-melanoma cells - immunochemical characterization with xenoantisera  Academic Article
  • Unique ability of integrin alpha(v)beta(3) to support tumor cell arrest under dynamic flow conditions  Academic Article
  • Unique glycoprotein-proteoglycan complex defined by monoclonal-antibody on human-melanoma cells  Academic Article
  • VE-cadherin-derived cell-penetrating peptide, pVEC, with carrier functions  Academic Article
  • kurtz, a novel nonvisual arrestin, is an essential neural gene in Drosophila  Academic Article

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