Scripps VIVO scripps research logo

  • Index
  • Log in
  • Home
  • People
  • Organizations
  • Research
  • Events
Search form

Macaca fascicularis

Concept
uri icon
  • Overview
scroll to property group menus

Overview

subject area of

  • 2-(Pyrrolidin-1-yl)ethyl-3,4-dihydroisoquinolin-1(2H)-one Derivatives as Potent and Selective Histamine-3 Receptor Antagonists  Academic Article
  • A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity  Academic Article
  • A two-antibody pan-ebolavirus cocktail confers broad therapeutic protection in ferrets and nonhuman primates  Academic Article
  • ARC15105 is a potent antagonist of von Willebrand factor mediated platelet activation and adhesion  Academic Article
  • Antibodies against cd14 protect primates from endotoxin-induced shock  Academic Article
  • Anticoagulant responses to thrombin are enhanced during regression of atherosclerosis in monkeys  Academic Article
  • Aptamer ARC19499 mediates a procoagulant hemostatic effect by inhibiting tissue factor pathway inhibitor  Academic Article
  • Atypical BSE (BASE) transmitted from asymptomatic aging cattle to a primate  Academic Article
  • B cell recognition of the conserved hiv-1 co-receptor binding site is altered by endogenous primate cd4  Academic Article
  • Brain and plasma kinetics of the opioid 11c-hydromorphone in 2 macaque species  Academic Article
  • Carboxyfullerene neuroprotection postinjury in Parkinsonian nonhuman primates  Academic Article
  • Characterization of H7N9 influenza A viruses isolated from humans  Academic Article
  • Chemical generation of bispecific antibodies  Academic Article
  • Coupling of receptors in brain membranes by fusion to the adenylate-cyclase system of a foreign effector cell  Academic Article
  • Cta1-dd adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization  Academic Article
  • DPP8 and DPP9 expression in cynomolgus monkey and Sprague Dawley rat tissues  Academic Article
  • Dietary fish oil-induced decrease in low-density-lipoprotein binding to fibroblasts is mediated by apolipoprotein-e  Academic Article
  • Discovery of 7-tetrahydropyran-2-yl chromans: β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors that reduce amyloid β-protein (Aβ) in the central nervous system  Academic Article
  • Discovery of ledipasvir (GS-5885): a potent, once-daily oral NS5A inhibitor for the treatment of hepatitis C virus infection  Academic Article
  • Discovery of piragliatin--first glucokinase activator studied in type 2 diabetic patients  Academic Article
  • Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition properties  Academic Article
  • Distribution of enkephalin and its relation to serotonin in cat and monkey spinal-cord and brain-stem  Academic Article
  • Efficacy of ABX196, a new NKT agonist, in prophylactic human vaccination  Academic Article
  • Elevated glutamate levels in the vitreous body of humans and monkeys with glaucoma  Academic Article
  • Evidence for coexistence between calcitonin gene-related peptide and serotonin in the bulbospinal pathway in the monkey  Academic Article
  • Expression of small cytoplasmic transcripts of the rat identifier element in vivo and in cultured cells  Academic Article
  • GNE-781, a highly advanced potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein, binding protein (CBP)  Academic Article
  • Galanin inhibits the potassium-evoked release of acetylcholine and the muscarinic receptor-mediated stimulation of phosphoinositide turnover in slices of monkey hippocampus  Academic Article
  • Human immunodeficiency virus type 1 env trimer immunization of macaques and impact of priming with viral vector or stabilized core protein  Academic Article
  • Humanized IgG(1) variants with differential binding properties to the neonatal Fc receptor: relationship to pharmacokinetics in mice and primates  Academic Article
  • Impaired anticoagulant response to infusion of thrombin in atherosclerotic monkeys associated with acquired defects in the protein c system  Academic Article
  • LY2875358, a neutralizing and internalizing anti-MET bivalent antibody, inhibits HGF-dependent and HGF-independent MET activation and tumor growth  Academic Article
  • Mechanistic pharmacokinetic-pharmacodynamic modeling of BACE1 inhibition in monkeys: development of a predictive model for amyloid precursor protein processing  Academic Article
  • Monoclonal antibody clearance. Impact of modulating the interaction of IgG with the neonatal Fc receptor  Academic Article
  • Patterns of cerebral-cortex messenger-rna expression  Academic Article
  • Phenol emulsion-enhanced DNA-driven subtractive cdna cloning - isolation of low-abundance monkey cortex-specific messenger-rnas  Academic Article
  • Piperazine-based CCR5 antagonists as HIV-1 inhibitors. II. Discovery of 1- (2,4-dimethyl-3-pyridinyl)carbonyl -4-methyl-4- 3(S)-methyl-4- 1(S)- 4-(trifluoro-methyl)phenyl ethyl -1-piperazinyl -piperidine N1-oxide (Sch-350634), an orally bioavailable, potent CCR5 antagonist  Academic Article
  • Piperazine-based CCR5 antagonists as HIV-1 inhibitors. IV. Discovery of 1- (4,6-dimethyl-5-pyrimidinyl)carbonyl -4- 4-{2-methoxy-1(R)-4-(trifluo romethyl)-phenyl}ethyl-3(S)-methyl-1-piperazinyl -4-methylpiperidine (Sch-417690/Sch-D), a potent, highly selective, and orally bioavailable CCR5 antagonist  Academic Article
  • Platelet factor 4 enhances generation of activated protein C in vitro and in vivo  Academic Article
  • PrP(TSE) distribution in a primate model of variant, sporadic, and iatrogenic Creutzfeldt-Jakob disease  Academic Article
  • Preclinical disposition and pharmacokinetics-pharmacodynamic modeling of biomarker response and tumour growth inhibition in xenograft mouse models of G-573, a MEK inhibitor  Academic Article
  • Preclinical evaluation in nonhuman primates of murine monoclonal anti-idiotype antibody that mimics the disialoganglioside gd2  Academic Article
  • Preclinical safety and pharmacokinetic profile of 3K3A-APC, a novel, modified activated protein C for ischemic stroke  Academic Article
  • Raxibacumab for the treatment of inhalational anthrax  Academic Article
  • Relationship of brain-derived neurotrophic factor and its receptor TrkB to altered inhibitory prefrontal circuitry in schizophrenia  Academic Article
  • Risk of oral infection with bovine spongiform encephalopathy agent in primates  Academic Article
  • Synaptic organization of serotonin-immunoreactive fibers in primary visual-cortex of the macaque monkey  Academic Article
  • Synthesis, structure-activity relationships, and in vivo evaluation of N3-phenylpyrazinones as novel corticotropin-releasing factor-1 (CRF1) receptor antagonists  Academic Article
  • Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth  Academic Article
  • The TB-specific CD4(+) T cell immune repertoire in both cynomolgus and rhesus macaques largely overlap with humans  Academic Article
  • The interplay of non-specific binding, target-mediated clearance and FcRn interactions on the pharmacokinetics of humanized antibodies  Academic Article
  • The rational design of selective benzoxazepin inhibitors of the α-isoform of phosphoinositide 3-kinase culminating in the identification of (S)-2-((2-(1-isopropyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo f imidazo 1,2-d 1,4 oxazepin-9-yl)oxy)propanamide (GDC-0326)  Academic Article
  • The relationship of glucokinase activator-induced hypoglycemia with arteriopathy, neuronal necrosis, and peripheral neuropathy in nonclinical studies  Academic Article
  • Tissue distribution of bovine spongiform encephalopathy agent in primates after intravenous or oral infection  Academic Article

©2019 The Scripps Research Institute | Terms of Use | Powered by VIVO

  • About
  • Contact Us
  • Support