subject area of

• "Don't know much bile-ology"  Academic Article
• 'Muscle-sparing' statins: preclinical profiles and future clinical use  Academic Article
• 1,3,8-Triazaspiro[4.5]decane-2,4-diones as efficacious pan-inhibitors of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) for the treatment of anemia  Academic Article
• 2-Propylthiouracil does not replace glutathione for the glutathione transferases  Academic Article
• 4-Hydroxyalk-2-enals are substrates for glutathione transferase  Academic Article
• 5-aminoimidazole-4-carboxyamide-ribonucleoside (AICAR)-stimulated hepatic expression of Cyp4a10, Cyp4a14, Cyp4a31, and other peroxisome proliferator-activated receptor alpha-responsive mouse genes is AICAR 5'-monophosphate-dependent and AMP-activated protein kinase-independent  Academic Article
• A 28,000-Da GDP/GTP-binding protein specific to the nuclear envelope  Academic Article
• A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase  Academic Article
• A cell-surface molecule involved in aggregation of embryonic liver-cells  Academic Article
• A chemical switch regulates fibrate specificity for peroxisome proliferator-activated receptor alpha (ppar alpha) versus liver x receptor  Academic Article
• A chemical, genetic, and structural analysis of the nuclear bile acid receptor fxr  Academic Article
• A chimeric mouse model of Gaucher disease  Academic Article
• A chromatin binding-site in the tail domain of nuclear lamins that interacts with core histones  Academic Article
• A common genetic polymorphism (46 C to T substitution) in the 5 '-untranslated region of the coagulation factor XII gene is associated with low translation efficiency and decrease in plasma factor XII level  Academic Article
• A continuous assay for the spectrophotometric analysis of sulfotransferases using aryl sulfotransferase iv  Academic Article
• A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid use  Academic Article
• A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange  Academic Article
• A function of the hepatitis B virus precore protein is to regulate the immune response to the core antigen  Academic Article
• A genetic-locus regulates the expression of tissue-specific messenger-rnas from multiple transcription units  Academic Article
• A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver  Academic Article
• A key role for lipoic acid synthesis during Plasmodium liver stage development  Academic Article
• A less costly regimen of alglucerase to treat gauchers-disease  Academic Article
• A liver-selective LXR inverse agonist that suppresses hepatic steatosis  Academic Article
• A method for the direct recording of an enzyme-catalyzed thiol-- disulfide interchange using a mixed disulfide of glutathione and 3-carboxy-4-nitrobenzenethiol  Academic Article
• A mouse model of accelerated liver aging caused by a defect in DNA repair  Academic Article
• A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis  Academic Article
• A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol with potential anti-obesity effects  Academic Article
• A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects  Academic Article
• A point mutation in sec61 alpha 1 leads to diabetes and hepatosteatosis in mice  Academic Article
• A proposed role for the immune-system in the pathogenesis of hepatitis-B virus-induced liver-disease  Academic Article
• A recombinant minigene vaccine containing a nonameric cytotoxic-t-lymphocyte epitope confers limited protection against listeria monocytogenes infection  Academic Article
• A role of apolipoprotein D in triglyceride metabolism  Academic Article
• A set of inhibitors for discrimination between the basic isozymes of glutathione transferase in rat liver  Academic Article
• A steady-state-kinetic model for formaldehyde dehydrogenase from human liver. A mechanism involving NAD+ and the hemimercaptal adduct of glutathione and formaldehyde as substrates and free glutathione as an allosteric activator of the enzyme  Academic Article
• A steady-state-kinetic random mechanism for glutathione S-transferase A from rat liver. A model involving kinetically significant enzyme-product complexes in the forward reaction  Academic Article
• A thymic precursor to the NK T cell lineage  Academic Article
• A transgenic mouse model of the chronic hepatitis B surface antigen carrier state  Academic Article
• ADH1C*2 allele is associated with alcohol dependence and elevated liver enzymes in Trinidad and Tobago  Academic Article
• ALS-linked mutant superoxide dismutase 1 (SOD1) alters mitochondrial protein composition and decreases protein import  Academic Article
• AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation  Academic Article
• AP-2-containing clathrin coats assemble on mature lysosomes  Academic Article
• Aberrant expression of fetal RNA-binding protein p62 in liver cancer and liver cirrhosis  Academic Article
• Absence of a ping-pong pathway in the kinetic mechanism of glutathione S-transferase A from rat liver. Evidence based on quantitative comparison of the asymptotic properties of experimental data and alternative rat equations  Academic Article
• Absence of carbohydrate response element binding protein in adipocytes causes systemic insulin resistance and impairs glucose transport  Academic Article
• Absence of mitochondrial superoxide dismutase results in a murine hemolytic anemia responsive to therapy with a catalytic antioxidant  Academic Article
• Acitretin in psoriasis: An overview of adverse effects  Academic Article
• Activated intrahepatic antigen-presenting cells inhibit hepatitis B virus replication in the liver of transgenic mice  Academic Article
• Activating transcription factor 4 increases chemotherapeutics resistance of human hepatocellular carcinoma  Academic Article
• Activation and transfer of novel synthetic 9-substituted sialic acids  Academic Article
• Activation of liver x receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue  Academic Article
• Activation of multidrug resistance (P-glycoprotein) mdr3/mdr1a gene during the development of hepatocellular carcinoma in hepatitis B virus transgenic mice  Academic Article
• Activity-based protein profiling in vivo using a copper(i)-catalyzed azide-alkyne 3+2 cycloaddition  Academic Article
• Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage-derived IL-6-dependent pathway  Academic Article
• Allosteric activators of glucokinase: potential role in diabetes therapy  Academic Article
• Alpha-Keto heterocycle inhibitors of fatty acid amide hydrolase: carbonyl group modification and alpha-substitution  Academic Article
• Altered expression of hepatic carcinogen metabolizing enzymes with liver injury in HBV transgenic mouse lineages expressing various amounts of hepatitis B surface antigen  Academic Article
• Alternative splicing within the ligand binding domain of the human constitutive androstane receptor  Academic Article
• An anatomical and temporal portrait of physiological substrates for fatty acid amide hydrolase  Academic Article
• An endoplasmic reticulum-specific cyclophilin  Academic Article
• An essential role of cytosolic thioltransferase in protection of pyruvate kinase from rabbit liver against oxidative inactivation  Academic Article
• An in vivo evaluation of amphiphilic, biodegradable peptide copolymers as siRNA delivery agents  Academic Article
• An innate host response to the neoplastic cell - syngeneic rat-tumor cells can elicit a rapid denovo lymphoid procoagulant response  Academic Article
• An investigation of specific interactions of deoxyribonucleic acid and lysine-rich (F1) histone preparations  Academic Article
• Analyses of autoantibodies against tumor-associated antigens in patients with hepatocellular carcinoma  Academic Article
• Analysis of Ran/TC4 function in nuclear protein import  Academic Article
• Analysis of homology-directed recombination in VDJ junctions from cytoplasmic Ig(-) pre-B-cells of newborn mice  Academic Article
• Analysis of the therapeutic functions of novel melanocortin receptor agonists in mc3r-and mc4r-deficient c57bl/6j mice  Academic Article
• Antibodies to peptides detect new hepatitis-b antigen - serological correlation with hepatocellular-carcinoma  Academic Article
• Antidiabetic action of a liver x receptor agonist mediated by inhibition of hepatic gluconeogenesis  Academic Article
• Antinarcotic effects of the standardized ginseng extract g115 on morphine  Academic Article
• Antiplatelet drug therapy moderates immune-mediated liver disease and inhibits viral clearance in mice infected with a replication-deficient adenovirus  Academic Article
• Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B  Academic Article
• Apolipoprotein a1 increases mitochondrial biogenesis through AMP-activated protein kinase  Academic Article
• Association of the ADHIB(*)3 allele with alcohol-related phenotypes in Trinidad  Academic Article
• Attenuation of experimental autoimmune hepatitis by exogenous and endogenous cannabinoids: Involvement of regulatory T cells  Academic Article
• Atypical nucleosome spacing of rat neuronal identifier elements in nonneuronal chromatin  Academic Article
• Autoantibody to a nuclear antigen in proliferating cells  Academic Article
• Azide reversibly raises cyclic GMP levels in hepatic slices and activates guanylate cyclase  Academic Article
• B lymphocyte development, heterogeneity, and function  Academic Article
• Bacterial superantigens mediate T-cell deletions in the mouse severe combined immunodeficiency human liver thymus model  Academic Article
• Beef liver catalase structure - interpretation of electron micrographs  Academic Article
• Benzo(a)pyrene metabolism by rat liver microsomes: effects of adding purified glutathione S-transferases A, B, and C  Academic Article
• Beta-cop is essential for transport of protein from the endoplasmic-reticulum to the golgi in-vitro  Academic Article
• Binary combinations of four protein subunits with different catalytic specificities explain the relationship between six basic glutathione S-transferases in rat liver cytosol  Academic Article
• Binding studies with intact rat prolactin and a 16K fragment of the hormone  Academic Article
• Bio-distribution, toxicity and pathology of cowpea mosaic virus nanoparticles in vivo  Academic Article
• Biochanin A, a naturally occurring inhibitor of fatty acid amide hydrolase  Academic Article
• Biochemical and structural analysis of nuclear protein import  Academic Article
• Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors  Academic Article
• Biophysical studies on the mechanism of quinacrine staining of chromosomes  Academic Article
• Biosynthesis of a disialylated sequence in n-linked oligosaccharides - identification of an n-acetylglucosaminide (alpha-2- 6)-sialyltransferase in golgi-apparatus from rat-liver  Academic Article
• Biosynthesis of lipopolysaccharide-binding protein in rabbit hepatocytes  Academic Article
• Blocking chemokine responsive to γ-2/interferon (IFN)-γ inducible protein and monokine induced by IFN-γ activity in vivo reduces the pathogenetic but not the antiviral potential of hepatitis B virus-specific cytotoxic T lymphocytes  Academic Article
• Bortezomib inhibits hepatitis B virus replication in transgenic mice  Academic Article
• Break of T cell ignorance to a viral antigen in the liver induces hepatitis  Academic Article
• Breaking tolerance leads to autoantibody production but not autoimmune liver-disease in hepatitis-B virus envelope transgenic mice  Academic Article
• Breaking tolerance to the natural human liver autoantigen cytochrome P450 2D6 by virus infection  Academic Article
• CD40 activation rescues antiviral CD8+ T cells from PD-1-mediated exhaustion  Academic Article
• Calcium signaling through CaMKII regulates hepatic glucose production in fasting and obesity  Academic Article
• Calcium-mediated changes in gap junction structure - evidence from the low-angle x-ray pattern  Academic Article
• Carbohydrate on human factor viii von willebrand factor - impairment of function by removal of specific galactose residues  Academic Article
• Carcinogen-binding proteins. High-affinity binding sites for benzo[a]pyrene in mouse liver distinct from the ah receptor  Academic Article
• Cargo selection by the COPII budding machinery during export from the ER  Academic Article
• Catalytic activities of human alpha class glutathione transferases toward carcinogenic dibenzo a,l pyrene diol epoxides  Academic Article
• Cd-113-h-1 spin-spin couplings in homonuclear h-1 correlated spectroscopy of metallothionein - identification of the cysteine h-1 spin systems  Academic Article
• Cell mediated immune response to the hepatitis C virus  Academic Article
• Cellular and molecular mechanisms of hepatocarcinogenesis  Academic Article
• Cellular expression of liver and neural cell-adhesion molecules after transfection with their cdnas results in specific cell cell binding  Academic Article
• Central nervous system melanocortin-3 receptors are required for synchronizing metabolism during entrainment to restricted feeding during the light cycle  Academic Article
• Characterization and nucleotide binding-properties of a mutant dihydropteridine reductase containing an aspartate 37-isoleucine replacement  Academic Article
• Characterization of UT2 cells. The induction of peroxisomal 3-hydroxy-3-methylglutaryl-coenzyme A reductase  Academic Article
• Characterization of a cDNA-encoding a human kidney, cytochrome-P-450 4A fatty-acid omega-hydroxylase and the cognate enzyme expressed in Escherichia-coli  Academic Article
• Characterization of a rabbit gene encoding a clofibrate-inducible fatty-acid omega-hydroxylase - CYP4A6  Academic Article
• Characterization of l-cam, a major cell-adhesion molecule from embryonic liver-cells  Academic Article
• Characterization of nuclear RNases that cleave hepatitis B virus RNA near the LA protein binding site  Academic Article
• Characterization of the CYP2C5 gene in 21L III/J rabbits. Allelic variation affects the expression of P450IIC5  Academic Article
• Characterization of the human protein S gene promoter: a possible role of transcription factors Sp1 and HNF3 in liver  Academic Article
• Characterization of the steroid-metabolizing capacity of the hepatic cytochrome-p450iic5 expressed in cos-1 cells - 3-beta-hydroxysteroid dehydrogenase delta-5- 4 isomerase type activity  Academic Article
• Chronic alcohol consumption generates a vulnerable immune environment during early SIV infection in rhesus macaques  Academic Article
• Chronic lymphocytic inflammation specifies the organ tropism of prions  Academic Article
• Cipc is a mammalian circadian clock protein without invertebrate homologues  Academic Article
• Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation  Academic Article
• Circadian oscillations of protein-coding and regulatory RNAs in a highly dynamic mammalian liver epigenome  Academic Article
• Circadian surprise: it's not all about transcription  Academic Article
• Circadian timing in central and peripheral tissues in a migratory songbird: dependence on annual life-history states  Academic Article
• Circadian transcriptional output in the SCN and liver of the mouse  Academic Article
• Circular dichroism studies of glutathione reductase  Academic Article
• Clathrin- and dynamin-dependent coated vesicle formation from isolated plasma membranes  Academic Article
• Clearance of hepatitis B virus from the liver of transgenic mice by short hairpin RNAs  Academic Article
• Clofarabine targets the large subunit (alpha) of human ribonucleotide reductase in live cells by assembly into persistent hexamers  Academic Article
• Clonidine blocks acquisition but not expression of conditioned opiate withdrawal in rats  Academic Article
• Cloning and characterization of cDNAs encoding 2,3,7,8-tetrachlorodibenzo-para-dioxin-inducible rabbit messenger-RNAs for cytochrome-P-450 isozyme-4 and isozyme-6  Academic Article
• Cloning and expression of cDNA for a human low-Km, rolipram-sensitive cyclic AMP phosphodiesterase  Academic Article
• Co-localization of inducible-nitric oxide synthase and plasmodium berghei in hepatocytes from rats immunized with irradiated sporozoites  Academic Article
• Coagulation studies and correlative histology during experimental hemoglobinemia in rabbits  Academic Article
• Codistribution of galactosyltransferase and sialyltransferase - reorganization of trans golgi-apparatus elements in hepatocytes in intact liver and cell-culture  Academic Article
• Comparative characterization of a wild type and transmembrane domain-deleted fatty acid amide hydrolase: Identification of the transmembrane domain as a site for oligomerization  Academic Article
• Comparative-analysis of the major polypeptides from liver gap-junctions and lens fiber junctions  Academic Article
• Comparison of glyoxalase I purified from yeast (Saccharomyces cerevisiae) with the enzyme from mammalian sources  Academic Article
• Comparison of the circulating metabolite profile of PF-04991532, a hepatoselective glucokinase activator, across preclinical species and humans: potential implications in metabolites in safety testing assessment  Academic Article
• Competitive selection in vivo by a cell for one variant over another: Implications for rna virus quasispecies in vivo  Academic Article
• Conformation of cd7 -metallothionein-2 from rat-liver in aqueous-solution determined by nuclear magnetic-resonance spectroscopy  Academic Article
• Conjugation of styrene oxide by the basic and acidic forms of glutathione transferase in the human fetal liver  Academic Article
• Constitutive forms of rabbit-liver microsomal cytochrome-P-450 - enzymatic diversity, polymorphism and allosteric regulation  Academic Article
• Coordinated transcription of key pathways in the mouse by the circadian clock  Academic Article
• Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses  Academic Article
• Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis  Academic Article
• Cryptochromes mediate rhythmic repression of the glucocorticoid receptor  Academic Article
• Cutting edge: Inhibition of hepatitis B virus replication by activated NK T cells does not require inflammatory cell recruitment to the liver  Academic Article
• Cyclic GMP efflux from liver slices  Academic Article
• Cyclin D3 maintains growth-inhibitory activity of C/EBPalpha by stabilizing C/EBPalpha-cdk2 and C/EBPalpha-Brm complexes  Academic Article
• Cytoimmunotherapy for persistent virus-infection reveals a unique clearance pattern from the central-nervous-system  Academic Article
• Cytosolic glutathione transferases from rat liver. Primary structure of class alpha glutathione transferase 8-8 and characterization of low-abundance class Mu glutathione transferases  Academic Article
• Cytosolic rat liver glutathione transferase 4-4. Primary structure of the protein reveals extensive differences between homologous glutathione transferases of classes alpha and mu  Academic Article
• Delayed and accelerated aging share common longevity assurance mechanisms  Academic Article
• Demonstration of an extensive tras-tubular network continuous with the golgi-apparatus stack that may function in glycosylation  Academic Article
• Dendritic cell immunization breaks cytotoxic T lymphocyte tolerance in hepatitis B virus transgenic mice  Academic Article
• Depletion of neutrophils blocks the recruitment of antigen-nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus-specific cytotoxic T lymphocytes  Academic Article
• Design and synthesis of hepatoselective, pyrrole-based HMG-CoA reductase inhibitors  Academic Article
• Detection of vitronectin mRNA in tissues and cells of the mouse  Academic Article
• Determination of the 3-dimensional structure of metallothioneins by nuclear-magnetic-resonance spectroscopy in solution  Academic Article
• Detoxication of base propenals and other alpha, beta-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferases  Academic Article
• Detoxification of styrene oxide by human liver glutathione transferase  Academic Article
• Development of a liver-targeted siRNA delivery platform with a broad therapeutic window utilizing biodegradable polypeptide-based polymer conjugates  Academic Article
• Development of an affinity chromatography resin for the purification of carcinogen binding proteins from mouse liver  Academic Article
• Diced electrophoresis gel assay for screening enzymes with specified activities  Academic Article
• Diet-genotype interactions in the development of the obese, insulin-resistant phenotype of C57BL/6J mice lacking melanocortin-3 or-4 receptors  Academic Article
• Differences among human tumor cell lines in the expression of glutathione transferases and other glutathione-linked enzymes  Academic Article
• Differences in stereoselectivity and catalytic efficiency of three human glutathione transferases in the conjugation of glutathione with 7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene  Academic Article
• Differences in the occurrence of glutathione transferase isoenzymes in rat lung and liver  Academic Article
• Different regulatory elements are required for response of hepcidin to interleukin-6 and bone morphogenetic proteins 4 and 9  Academic Article
• Differential antitumor effects of administration of recombinant IL-18 or recombinant IL-12 are mediated primarily by Fas-Fas ligand- and perforin-induced tumor apoptosis, respectively  Academic Article
• Differential dynamics of the peripheral and intrahepatic cytotoxic T lymphocyte response to hepatitis B surface antigen  Academic Article
• Differential effects of phthalates on the testis and the liver  Academic Article
• Differential expression of cytochrome-p-450-1 and related forms in rabbit liver and kidney  Academic Article
• Differential proteomic analysis of mammalian tissues using SILAM  Academic Article
• Differential regulation of vitronectin in mice and humans in vitro  Academic Article
• Differential target cell sensitivity to CTL-activated death pathways in hepatitis B virus transgenic mice  Academic Article
• Dihydroquinazolinone inhibitors of proliferation of blood and liver stage malaria parasites  Academic Article
• Discovering disease-associated enzymes by proteome reactivity profiling  Academic Article
• Discovery of a highly selective CYP3A4 inhibitor suitable for reaction phenotyping studies and differentiation of CYP3A4 and CYP3A5  Academic Article
• Discovery of gene function by expression profiling of the malaria parasite life cycle  Academic Article
• Discovery of novel hepatoselective HMG-CoA reductase inhibitors for treating hypercholesterolemia: A bench-to-bedside case study on tissue selective drug distribution  Academic Article
• Discovery of piragliatin--first glucokinase activator studied in type 2 diabetic patients  Academic Article
• Discovery of pyrrole-based hepatoselective ligands as potent inhibitors of HMG-CoA reductase  Academic Article
• Dissection of the insulin-sensitizing effect of liver x receptor ligands  Academic Article
• Dissociation of vasoconstrictor and platelet aggregatory activities of thromboxane by carbocyclic thromboxane-a2, a stable analog of thromboxane-a2  Academic Article
• Distinct calcium-independent and calcium-dependent adhesion systems of chicken-embryo cells  Academic Article
• Distribution of vitronectin mRNA during murine development  Academic Article
• Disubstituted piperidines as potent orexin (hypocretin) receptor antagonists  Academic Article
• Does tenofovir influence efavirenz pharmacokinetics?  Academic Article
• Dose-response in a high density three-dimensional liver device with real-time bioenergetic and metabolic flux quantification  Academic Article
• Early epochal maps of 2 different cell-adhesion molecules  Academic Article
• Ecto-5'-nucleotidase (CD73) regulates host inflammatory responses and exacerbates murine salmonellosis  Academic Article
• Ectopic expression of prion protein (prp) in t lymphocytes or hepatocytes of prp knockout mice is insufficient to sustain prion replication  Academic Article
• Effect of 2,3,7,8-tetrachlorodibenzo-para-dioxin and phenobarbital on the occurrence and distribution of 4 cytochrome-P-450 isozymes in rabbit kidney, lung, and liver  Academic Article
• Effect of bilateral 6-hydroxydopamine lesions of the medial forebrain bundle on reaction time  Academic Article
• Effect of chronic hypoxia on detoxication enzymes in rat liver  Academic Article
• Effect of inducers of drug-metabolizing enzymes on glutathione reductase and glutathione peroxidase in rat liver  Academic Article
• Effective anti-hepatitis B virus hammerhead ribozymes derived from multimeric precursors  Academic Article
• Effector CD8 T cell trafficking within the liver  Academic Article
• Effector role of blood monocytes in experimental visceral leishmaniasis  Academic Article
• Effects of acetylbergenin against d-galactosamine-induced hepatotoxicity in rats  Academic Article
• Effects of inducers of drug metabolism on basic hepatic forms of mouse glutathione transferase  Academic Article
• Electron microscopic image analysis of cardiac gap junction membrane crystals  Academic Article
• Electron-transfer from cytochrome-b5 to iron and copper-complexes  Academic Article
• Electrophoretic polymorphism of glutathione peroxidase  Academic Article
• Electrophoretic purification of a water-soluble guinea pig transplantation antigen  Academic Article
• Elevations of hepatic quinone reductase, glutathione, and α- and μ-class glutathione S-transferase isoforms in mice with chronic hepatitis: a compensatory response to injury  Academic Article
• Elimination of duck hepatitis B virus RNA-containing capsids in duck interferon-alpha-treated hepatocytes  Academic Article
• Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation  Academic Article
• Endogenous formation and repair of oxidatively induced g (8-5m) T intrastrand cross-link lesion  Academic Article
• Endosomolytic bioreducible poly(amido amine disulfide) polymer conjugates for the in vivo systemic delivery of siRNA therapeutics  Academic Article
• Endothelin receptor remodeling induces the portal venous hyper-response to endothelin-1 following endotoxin pretreatment  Academic Article
• Enforced bcl-2 expression inhibits antigen-mediated clonal elimination of peripheral b cells in an antigen dose-dependent manner and promotes receptor editing in autoreactive, immature b cells  Academic Article
• Enhanced in situ detection of beta-glucuronidase activity in murine tissue  Academic Article
• Enzymatic catalysis of the reversible sulfitolysis of glutathione disulfide and the biological reduction of thiosulfate esters  Academic Article
• Enzymes involved in glutathione metabolism in rat liver and blood after carbon tetrachloride intoxication  Academic Article
• Enzymic cyclization of trans,trans,trans-18,19-dehydrosqualene 2,3-oxide  Academic Article
• Escherichia coli infection induces autoimmune cholangitis and anti-mitochondrial antibodies in non-obese diabetic (NOD). B6 (Idd10/Idd18) mice  Academic Article
• Evaluation of NHS carbamates as a potent and selective class of endocannabinoid hydrolase inhibitors  Academic Article
• Evaluation of rna-binding specificity of aminoglycosides with DNA microarrays  Academic Article
• Evidence for a glutathione-dependent interconversion of two forms of a thioltransferase from rat liver catalyzing thiol-disulfide interchange  Academic Article
• Evidence for gene conversion in genes for cell-adhesion molecules  Academic Article
• Evidence that extrahepatic cells express vitronectin mRNA at rates approaching those of hepatocytes  Academic Article
• Evidence that variation among untreated rabbits in hepatic progesterone 21-hydroxylase activity is indicative of enzyme heterogeneity rather than a transient inductive effect  Academic Article
• Exacerbation of murine listeriosis by a monoclonal-antibody specific for the type-3 complement receptor of myelomonocytic cells - absence of monocytes at infective foci allows listeria to multiply in nonphagocytic cells  Academic Article
• Exceptionally potent inhibitors of fatty acid amide hydrolase: the enzyme responsible for degradation of endogenous oleamide and anandamide  Academic Article
• Excessive ethanol drinking following a history of dependence: Animal model of allostasis  Academic Article
• Expansion and contraction of the hepatitis B virus transcriptional template in infected chimpanzees  Academic Article
• Expression of hepatitis B virus large envelope polypeptide inhibits hepatitis B surface antigen secretion in transgenic mice  Academic Article
• Expression of rabbit cytochromes-p4504a which catalyze the omega-hydroxylation of arachidonic-acid, fatty-acids, and prostaglandins  Academic Article
• Expression of the hepatitis-delta virus large and small antigens in transgenic mice  Academic Article
• Extralymphatic virus sanctuaries as a consequence of potent T-cell activation  Academic Article
• Extremely long-lived nuclear pore proteins in the rat brain  Academic Article
• Extrinsic modulation of human T-lymphocyte E rosette function associated with prolonged hepatocellular injury after viral hepatitis  Academic Article
• Fate of hl-a antigens in aging cultured human diploid cell strains. Ii. Quantitative absorption studies  Academic Article
• Fatty acid amide hydrolase determines anandamide-induced cell death in the liver  Academic Article
• Formation of nuclear bodies in hepatocytes of estrogen-treated roosters  Academic Article
• Formation of prostamides from anandamide in FAAH knockout mice analyzed by HPLC with tandem mass spectrometry  Academic Article
• Frequency and avidity of specific antigen-binding cells in developing mice  Academic Article
• Functional organization of the mammalian genome  Academic Article
• Functional properties of lymphocyte subpopulations in hepatitis B virus infection. II. Cytotoxic effector cell killing of targets that naturally express hepatitis B surface antigen and liver-specific lipoprotein  Academic Article
• Functional proteomic and structural insights into molecular recognition in the nitrilase family enzymes  Academic Article
• Functional significance of endothelin B receptors in mediating sinusoidal and extrasinusoidal effects of endothelins in the intact rat liver  Academic Article
• Further characterization of hormonal regulation of glutathione transferase in rat liver and adrenal glands. Sex differences and demonstration that growth hormone regulates the hepatic levels  Academic Article
• G protein-coupled receptor 21 deletion improves insulin sensitivity in diet-induced obese mice  Academic Article
• Gamma-globin gene expression in chemical inducer of dimerization (cid)-dependent multipotential cells established from human beta-globin locus yeast artificial chromosome (beta-yac) transgenic mice  Academic Article
• Ganglioside gm2 as a human-tumor antigen (ofa-i-1)  Academic Article
• Gene expression during the priming phase of liver regeneration after partial hepatectomy in mice  Academic Article
• Gene expression profiles of human liver cells mediated by hepatitis b virus x protein  Academic Article
• Gene-expression in rat-brain  Academic Article
• General specificity of cytoplasmic thioltransferase (thiol:disulfide oxidoreductase) from rat liver for thiol and disulfide substrates  Academic Article
• Generation and phenotypic analysis of protein S-deficient mice  Academic Article
• Genetic reassortants of lymphocytic choriomeningitis virus - unexpected disease and mechanism of pathogenesis  Academic Article
• Genetic regulation of commitment to interleukin 4 production by a cd4(+) t cell-intrinsic mechanism  Academic Article
• Genomic analysis of the host response to hepatitis B virus infection  Academic Article
• Genomic and biological variation among commonly used lymphocytic choriomeningitis virus-strains  Academic Article
• Genomic profiles and predictors of early allograft dysfunction after human liver transplantation  Academic Article
• Ghrelin receptor (GHS-R1A) agonists show potential as interventive agents during aging  Academic Article
• Glucosamine activates autophagy in vitro and in vivo  Academic Article
• Glutathione S-transferases in human fetal liver  Academic Article
• Glutathione conjugation of trans-3,4-dihydroxy 1,2-epoxy 1,2,3,4-tetrahydrobenzo[c]phenanthrene isomers by human glutathione transferases  Academic Article
• Glutathione peroxidase  Academic Article
• Glutathione reductase  Academic Article
• Glutathione transferase isoenzymes from rat liver cytosol  Academic Article
• Glutathione transferases from human liver  Academic Article
• Glutathione transferases in rat lung: the presence of transferase 7-7, highly efficient in the conjugation of glutathione with the carcinogenic (+)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-oxy-7,8,9,10-tetrahydrobenzo[a]pyrene  Academic Article
• Glutathione transferases in rat testis  Academic Article
• Glyoxalase I, a zinc metalloenzyme of mammals and yeast  Academic Article
• Growth hormone (gh) status regulates gh receptor and gh binding protein mrna in a tissue- and transcript-specific manner but has no effect on insulin-like growth factor-i receptor mrna in the rat  Academic Article
• Growth hormone corrects proliferation and transcription of phosphoenolpyruvate carboxykinase in livers of old mice via elimination of CCAAT/enhancer-binding protein alpha-Brm complex  Academic Article
• Growth-hormone (gh) and insulin-like growth-factor-i (igf-i) treatment of the gh-deficient dwarf rat - differential-effects on igf-i transcription start site expression in hepatic and extrahepatic tissues and lack of effect on type-i igf receptor messenger-rna expression  Academic Article
• Guanine-nucleotide dissociation inhibitor is essential for rab1 function in budding from the endoplasmic-reticulum and transport through the golgi stack  Academic Article
• Gut microbiota regulate hepatic von Willebrand factor synthesis and arterial thrombus formation via Toll-like receptor-2  Academic Article
• HBsAg retention sensitizes the hepatocyte to injury by physiological concentrations of interferon‐γ  Academic Article
• HLA class I allelic diversity and progression of fibrosis in patients with chronic hepatitis C  Academic Article
• Harmonics of circadian gene transcription in mammals  Academic Article
• Heavy-metals and adenosine cyclic 3',5'-monophosphate metabolism - possible relevance to heavy-metal toxicity  Academic Article
• Heme-thiolate sulfenylation of human cytochrome P450 4A11 functions as a redox switch for catalytic inhibition  Academic Article
• Hepatic delivery of RNA interference activators for therapeutic application  Academic Article
• Hepatic disposition and biliary excretion of bilirubin and bilirubin glucuronides in intact rats. Differential processing of pigments derived from intra- and extrahepatic sources  Academic Article
• Hepatic glucose sensing via the CREB coactivator CRTC2  Academic Article
• Hepatic preneoplasia in hepatitis-B virus transgenic mice  Academic Article
• Hepatic receptor that specifically binds oligosaccharides containing fucosyl alpha1- 3 n-acetylglucosamine linkages  Academic Article
• Hepatitis B virus RNA-binding proteins associated with cytokine-induced clearance of viral RNA from the liver of transgenic mice  Academic Article
• Hepatitis B virus replication and viral antigen synthesis in hepatocyte lines derived from normal human liver  Academic Article
• Hepatitis B virus replication is cell cycle independent during liver regeneration in transgenic mice  Academic Article
• Hepatitis C virus core and E2 protein expression in transgenic mice  Academic Article
• Hepatitis-B virus nucleocapsid particles do not cross the hepatocyte nuclear-membrane in transgenic mice  Academic Article
• Hepatocarcinogenesis due to chronic liver-cell injury in hepatitis-B virus transgenic mice  Academic Article
• Hepatocyte nuclear factor-4-independent synthesis of coagulation factor vii in breast cancer cells and its inhibition by targeting selective histone acetyltransferases  Academic Article
• Hepatocytes with extensive telomere deprotection and fusion remain viable and regenerate liver mass through endoreduplication  Academic Article
• Heterologous expression of the allelic variant mu-class glutathione transferases mu and psi  Academic Article
• Heterotopic liver transplantation utilizing inbred rat strains. I. Characterization of allogeneic graft rejection and the effects of biliary obstruction and portal vein circulation on liver regeneration  Academic Article
• High-level hepatitis-B virus-replication in transgenic mice  Academic Article
• High-resolution fluorescence microscope imaging of erythroblast structure  Academic Article
• Highly sulfated glycosaminoglycans augment the cross-linking of vitronectin by guinea pig liver transglutaminase. Functional studies of the cross-linked vitronectin multimers  Academic Article
• Histone deacetylase inhibitor (HDACi) suberoylanilide hydroxamic acid (SAHA)-mediated correction of alpha 1-antitrypsin deficiency  Academic Article
• Horseradish peroxidase catalyzed hydroxylations: Mechanistic studies  Academic Article
• Host-virus interactions during malaria infection in hepatitis B virus transgenic mice  Academic Article
• Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment  Academic Article
• Hybrid periportal hepatocytes regenerate the injured liver without giving rise to cancer  Academic Article
• Hydrodynamic injection of viral DNA: A mouse model of acute hepatitis B virus infection  Academic Article
• Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver  Academic Article
• Hyperactive Himar1 transposase mediates transposition in cell culture and enhances gene expression in vivo  Academic Article
• Hypomorphic mutation in the site-1 protease Mbtps1 endows resistance to persistent viral infection in a cell-specific manner  Academic Article
• IKK beta is required for prevention of apoptosis mediated by cell-bound but not by circulating TNF alpha  Academic Article
• Identification of a gal-beta-1 - 3glcnac alpha-2 - 3 sialyltransferase in rat-liver  Academic Article
• Identification of a major polypeptide of the nuclear-pore complex  Academic Article
• Identification of a new glutathione S-transferase in human liver  Academic Article
• Identification of a nuclear protein (Scl-70) as a unique target of human antinuclear antibodies in scleroderma  Academic Article
• Identification of novel protein tyrosine phosphatases of hematopoietic cells by polymerase chain reaction amplification  Academic Article
• Identification of peroxisome proliferator-responsive human genes by elevated expression of the peroxisome proliferator-activated receptor a in HepG2 cells  Academic Article
• Identification of rabbit microsomal cytochrome-P-450 isoenzyme, form-1, as a hepatic progesterone 21-hydroxylase  Academic Article
• Identification of small molecule activators of cryptochrome  Academic Article
• Identification of specific binding-proteins for a nuclear location sequence  Academic Article
• Identification of the isozymes of glutathione transferase induced by trans-stilbene oxide  Academic Article
• Identification of the tyrosine phosphatase PTP-MEG2 as an antagonist of hepatic insulin signaling  Academic Article
• Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties  Academic Article
• Ifit1 protects against lipopolysaccharide and D-galactosamine-induced fatal hepatitis by inhibiting activation of the JNK Pathway  Academic Article
• Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery  Academic Article
• Immune pathogenesis of hepatocellular carcinoma  Academic Article
• Immune suppression uncovers endogenous cytopathic effects of the hepatitis B virus  Academic Article
• Immunization of experimental-animals with dihydrolipoamide acetyltransferase, as a purified recombinant polypeptide, generates mitochondrial antibodies but not primary biliary-cirrhosis  Academic Article
• Immunobiology and pathogenesis of hepatocellular injury in hepatitis-B virus transgenic mice  Academic Article
• Immunogenicity and tolerogenicity of hepatitis B virus structural and nonstructural proteins: Implications for immunotherapy of persistent viral infections  Academic Article
• Immunohistochemical study of allergic encephalomyelitis  Academic Article
• Immunological aspects of hepatitis-B virus-infection  Academic Article
• Immunological comparison of glyoxalase I from yeast and mammals and quantitative determination of the enzyme in human tissues by radioimmunoassay  Academic Article
• Immunological disease induced by injecting F1 lymphoid cells into certain parental strains  Academic Article
• Immunology and the liver  Academic Article
• Immunopathology of adoptive immunization in mice chronically infected with lymphocytic choriomeningitis virus  Academic Article
• Immunosurveillance of the liver by intravascular effector CD8(+) T cells  Academic Article
• Impact of somatic mutation on the S107(T15) heavy-chain V region of antibodies reactive with self and nonself  Academic Article
• Impaired genome maintenance suppresses the growth hormone-insulin-like growth factor 1 axis in mice with cockayne syndrome  Academic Article
• Importance of cellular microenvironment and circulatory dynamics in b cell immunotherapy  Academic Article
• In silico qtl mapping of basal liver iron levels in inbred mouse strains  Academic Article
• In vitro imaging and in vivo liver targeting with carbohydrate capped quantum dots  Academic Article
• In vivo cleavage of alpha 2,6-sialyltransferase by alzheimer beta-secretase  Academic Article
• In vivo study of the HC-TN strain of hepatitis C virus recovered from a patient with fulminant hepatitis: RNA transcripts of a molecular clone (pHC-TN) are infectious in chimpanzees but not in Huh7.5 cells  Academic Article
• Inactivation of carcinogenic diol epoxides of dibenzo a,l pyrene (dibenzo def,p chrysene) by human alpha class glutathione transferases  Academic Article
• Inactivation of pkc theta leads to increased susceptibility to obesity and dietary insulin resistance in mice  Academic Article
• Increase in the amount of glutathione transferase 4-4 in the rat adrenal gland after hypophysectomy and down-regulation by subsequent treatment with adrenocorticotrophic hormone  Academic Article
• Increased hepatic levels of the insulin receptor inhibitor, PC-1/NPP1, induce insulin resistance and glucose intolerance  Academic Article
• Increased production of apolipoprotein B-containing lipoproteins in the absence of hyperlipidemia in transgenic mice expressing cholesterol 7α-hydroxylase  Academic Article
• Increased survival and reduced neutrophil infiltration of the liver in Rab27a-but not Munc13-4-deficient mice in lipopolysaccharide-induced systemic inflammation  Academic Article
• Increasing the chemical potential of the germ-line antibody repertoire  Academic Article
• Induction of cyclin messenger-rna and cyclin-associated histone-h1 kinase during liver-regeneration  Academic Article
• Induction of glutathione S-transferases A, B and C in rat liver cytosol by trans-stilbene oxide  Academic Article
• Induction of plasminogen activator inhibitor 1 gene expression in murine liver by lipopolysaccharide. Cellular localization and role of endogenous tumor necrosis factor-alpha  Academic Article
• Inhibition of glutathione reductase by interaction of 2, 4, 6-trinitrobenzenesulfonate with the active-site dithiol  Academic Article
• Inhibition of hepatitis B virus in mice by RNA interference  Academic Article
• Inhibition of hepatitis B virus replication during adenovirus and cytomegalovirus infections in transgenic mice  Academic Article
• Inhibitors for distinction of three types of human glutathione transferase  Academic Article
• Initiation of replication in chromosomal DNA induced by extracts from proliferating cells  Academic Article
• Insulin-like growth factor-i: Compartmentalization within the somatotropic axis?  Academic Article
• Integral membrane proteins of the nuclear envelope interact with lamins and chromosomes, and binding is modulated by mitotic phosphorylation  Academic Article
• Interaction between apob and hepatic lipase mediates the uptake of apob-containing lipoproteins  Academic Article
• Interferon-production during lymphocytic choriomeningitis virus-infection of nude and normal mice  Academic Article
• Interferon-regulated pathways that control hepatitis B virus replication in transgenic mice  Academic Article
• Interleukin-12 inhibits hepatitis B virus replication in transgenic mice  Academic Article
• Interleukin-18 inhibits hepatitis B virus replication in the livers of transgenic mice  Academic Article
• Interleukin-2 and alpha/beta interferon down-regulate hepatitis B virus gene expression in vivo by tumor necrosis factor-dependent and -independent pathways  Academic Article
• Intracellular hepatitis B virus nucleocapsids survive cytotoxic T-lymphocyte-induced apoptosis  Academic Article
• Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes  Academic Article
• Intrahepatic expression of serum hepatitis virus-associated antigens  Academic Article
• Intrahepatic induction of alpha/beta interferon eliminates viral RNA-containing capsids in hepatitis B virus transgenic mice  Academic Article
• Intrahepatic, nucleocapsid antigen-specific T cells in chronic active hepatitis B  Academic Article
• Isolation and angiogenesis by endothelial progenitors in the fetal liver  Academic Article
• Isolation and characterization of maclura pomifera (mp) lectin  Academic Article
• Isolation and characterization of nuclear ribonucleoprotein complexes using human anti-nuclear ribonucleoprotein antibodies  Academic Article
• Isolation of a cdna clone for the liver-cell adhesion molecule (l-cam)  Academic Article
• Issues in immunologically-mediated hepatic-injury  Academic Article
• Kinetic and immunochemical studies of a receptor-like protein that binds aromatic hydrocarbons  Academic Article
• Kinetic independence of the subunits of cytosolic glutathione transferase from the rat  Academic Article
• Knockdown of damage-specific DNA binding protein 1 (ddb1) enhances the hbx-sirna-mediated inhibition of hbv replication  Academic Article
• Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis  Academic Article
• LDL receptor-related protein 1 regulates the abundance of diverse cell-signaling proteins in the plasma membrane proteome  Academic Article
• LPS inhibits endothelin-1-induced endothelial NOS activation in hepatic sinusoidal cells through a negative feedback involving caveolin-1  Academic Article
• Lack of N-regions in fetal and neonatal mouse immunoglobulin V-D-J junctional sequences  Academic Article
• Lack of detection of negative-strand hepatitis C virus RNA in peripheral blood mononuclear cells and other extrahepatic tissues by the highly strand-specific rTth reverse transcriptase PCR  Academic Article
• Large-scale expression of recombinant sialyttransferases and comparison of their kinetic-properties with native enzymes  Academic Article
• Lethal escherichia-coli septic shock is prevented by blocking tissue factor with monoclonal-antibody  Academic Article
• Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver  Academic Article
• Ligand-mediated retargeting of recombinant adenovirus for gene transfer in vivo  Academic Article
• Limited hepatitis B virus replication space in the chronically hepatitis C virus-infected liver  Academic Article
• Linear organization of the liver-cell adhesion molecule l-cam  Academic Article
• Lipopolysaccharide binding protein expression in primary human hepatocytes and HepG2 hepatoma cells  Academic Article
• Lipoxins-a4 and lipoxins-b4 - comparison of icosanoids having bronchoconstrictor and vasodilator actions but lacking platelet aggregatory activity  Academic Article
• Liver (b-type) phosphofructokinase messenger-rna - cloning, structure, and expression  Academic Article
• Liver autoimmunity triggered by microbial activation of natural killer T cells  Academic Article
• Liver capsule: Age-influenced hepatic immune priming determines HBV infection fate: Implications from mouse to man  Academic Article
• Liver is liver and blood is blood, and finally the twain have met  Academic Article
• Liver-cells contain constitutive DNase I-hypersensitive sites at the xenobiotic response element-1 and element-2 (XRE1 and XRE2) of the rat cytochrome-P-450IA1 gene and a constitutive, nuclear XRE-bindingfactor that is distinct from the dioxin receptor  Academic Article
• Liver-directed gene transfer: a linear polyethylenimine derivative mediates highly efficient DNA delivery to primary hepatocytes in vitro and in vivo  Academic Article
• Liver-expressed Igκ superantigen induces tolerance of polyclonal B cells by clonal deletion not κ to λ receptor editing  Academic Article
• Liver-specific protein in perspective  Academic Article
• Localization of sites of interaction between p23 and hsp90 in solution  Academic Article
• Loss-of-function mutation in myostatin reduces tumor necrosis factor alpha production and protects liver against obesity-induced insulin resistance  Academic Article
• Luteinizing-hormone-releasing hormone (lh-rh) binding to purified rat pituitary nuclei  Academic Article
• Lymphocyte-instructed monocyte induction of the coagulation pathways parallels the induction of hepatitis by the murine hepatitis-virus  Academic Article
• MMPs are required for recruitment of antigen-nonspecific mononuclear cells into the liver by CTLs  Academic Article
• Mammalian Sly1 regulates syntaxin 5 function in endoplasmic reticulum to Golgi transport  Academic Article
• Measurement of the isotope enrichment of stable isotope-labeled proteins using high-resolution mass spectra of peptides  Academic Article
• Mechanism of action of enzymes catalyzing thiol-disulfide interchange. Thioltransferases rather than transhydrogenases  Academic Article
• Mechanisms of class-I restricted immunopathology - A transgenic mouse model of fulminant-hepatitis  Academic Article
• Mechanistic characterization of a 2-thioxanthine myeloperoxidase inhibitor and selectivity assessment utilizing click chemistry-activity-based protein profiling  Academic Article
• Medicinal chemistry design principles for liver targeting through OATP transporters  Academic Article
• Melanocortin signaling in the cns directly regulates circulating cholesterol  Academic Article
• Membrane lipids are key modulators of the endocannabinoid-hydrolase FAAH  Academic Article
• Membrane topology and quaternary structure of cardiac gap junction ion channels  Academic Article
• Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota  Academic Article
• Metabolic benefit of chronic caloric restriction and activation of hypothalamic AGRP/NPY neurons in male mice is independent of ghrelin  Academic Article
• Metabolic syndrome: F stands for fructose and fat  Academic Article
• Metabolism of xenobiotics in hepatocyte nodules  Academic Article
• Metal coordination in rat-liver metallothionein-2 prepared with or without reconstitution of the metal-clusters, and comparison with rabbit liver metallothionein-2  Academic Article
• Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis  Academic Article
• Metformin inhibits hepatic mTORC1 signaling via dose-dependent mechanisms involving AMPK and the TSC complex  Academic Article
• Methods for delivery of adenoviral vectors to tumor vasculature  Academic Article
• Mir-214-dependent regulation of the Polycomb protein Ezh2 in skeletal muscle and embryonic stem cells  Academic Article
• Modulating endogenous gene expression of mammalian cells via RNA-small molecule interaction  Academic Article
• Modulation of early inflammatory reactions to promote engraftment and function of transplanted pancreatic islets in autoimmune diabetes  Academic Article
• Molecular and catalytic properties of glutathione transferase mu from human liver: an enzyme efficiently conjugating epoxides  Academic Article
• Molecular and functional characterization of the p62 complex, an assembly of nuclear pore complex glycoproteins  Academic Article
• Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides  Academic Article
• Molecular characterization of human and mouse fatty acid amide hydrolases  Academic Article
• Molecular cloning and characterization of human fetal liver tropomodulin. A tropomyosin-binding protein  Academic Article
• Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature  Academic Article
• Molecular network analysis of phosphotyrosine and lipid metabolism in hepatic PTP1b deletion mice  Academic Article
• Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice  Academic Article
• Molecular structure determination by electron microscopy of unstained crystalline specimens  Academic Article
• Molecular-cloning of aldolases for synthetic applications  Academic Article
• Monoclonal antibodies against vasoactive intestinal polypeptide: Studies of structure and related antigens  Academic Article
• Monoclonal antibodies to cytochrome p-450 immunopurify a 45-kda protein from a human lymphoblastoid cell line  Academic Article
• Monoclonal-antibodies identify a group of nuclear-pore complex glycoproteins  Academic Article
• Mouse genetics at work: a new model of chronic hepadnavirus infection - Comments  Academic Article
• Mouse liver repopulation with hepatocytes generated from human fibroblasts  Academic Article
• Mouse liver-specific CD8(+) T-cells encounter their cognate antigen and acquire capacity to destroy target hepatocytes  Academic Article
• Multiple inhibition of glutathione S-transferase A from rat liver by glutathione derivatives: kinetic analysis supporting a steady-state random sequential mechanism  Academic Article
• Murine cerebral malaria development is independent of toll-like receptor signaling  Academic Article
• N-methyl-N'-nitro-N-nitrosoguanidine and cyclic GMP stimulate phosphorylation of nuclear proteins from rat liver  Academic Article
• Naive HIV/HCV-coinfected patients have higher intrahepatic pro-inflammatory cytokines than coinfected patients treated with antiretroviral therapy  Academic Article
• Native hepatitis B virions and capsids visualized by electron cryomicroscopy  Academic Article
• Natural killer cell-mediated contact sensitivity develops rapidly and depends on interferon-α, interferon-γ and interleukin-12  Academic Article
• Natural killer, but not natural killer T, cells play a necessary role in the promotion of an innate antitumor response induced by IL-18  Academic Article
• Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin-6  Academic Article
• Nicotine self-administration acutely activates brain reward systems and induces a long-lasting increase in reward sensitivity  Academic Article
• Nitric oxide inhibits hepatitis B virus replication in the livers of transgenic mice  Academic Article
• Noncytopathic clearance of lymphocytic choriomeningitis virus from the hepatocyte  Academic Article
• Nonhereditary enhancement of progeny growth  Academic Article
• Normal growth and development in the absence of hepatic insulin-like growth factor i  Academic Article
• Novel antiviral host factor, TNK1, regulates IFN signaling through serine phosphorylation of STAT1  Academic Article
• Novel endosomolytic poly(amido amine) polymer conjugates for systemic delivery of siRNA to hepatocytes in rodents and nonhuman primates  Academic Article
• Novel sequence determinants in peroxisome proliferator signaling  Academic Article
• Nuclear covalently closed circular viral genomic DNA in the liver of hepatocyte nuclear factor 1 alpha-null hepatitis B virus transgenic mice  Academic Article
• Nuclear envelope transmembrane proteins (nets) that are up-regulated during myogenesis  Academic Article
• Nuclear membrane proteins with potential disease links found by subtractive proteomics  Academic Article
• Nuclear-pore complex glycoproteins contain cytoplasmically disposed o-linked n-acetylglucosamine  Academic Article
• Nuclear-protein import in permeabilized mammalian-cells requires soluble cytoplasmic factors  Academic Article
• Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export  Academic Article
• O-GlcNAc transferase/host cell factor C1 complex regulates gluconeogenesis by modulating PGC-1α stability  Academic Article
• Ongoing murine T1 or T2 immune responses to the hepatitis B surface antigen are excluded from the liver that expresses transgene-encoded hepatitis B surface antigen  Academic Article
• Opposing roles of peroxisome proliferator-activated receptor alpha and growth hormone in the regulation of CYP4A11 expression in a transgenic mouse model  Academic Article
• Organ distribution of glutathione transferase isoenzymes in the human fetus: differences between liver and extrahepatic tissues  Academic Article
• Organization of connexons in isolated rat-liver gap-junctions  Academic Article
• Organization of the beta-galactoside alpha-2,6-sialyltransferase gene - evidence for the transcriptional regulation of terminal glycosylation  Academic Article
• Organization of the neural cell-adhesion molecule (n-cam) gene - alternative exon usage as the basis for different membrane-associated domains  Academic Article
• Oscillating CD8(+) T cell effector functions after antigen recognition in the liver  Academic Article
• Overexpression of the IGF2-mRNA binding protein p62 in transgenic mice induces a steatotic phenotype  Academic Article
• Overexpression of the multidrug resistance gene mdr3 in spontaneous and chemically-induced mouse hepatocellular carcinomas  Academic Article
• Overexpression, one-step purification and characterization of udp-glucose dehydrogenase and udp-n-acetylglucosamine pyrophosphorylase  Academic Article
• Oxidase activity of glutathione reductase effected by 2,4,5-trinitrobenzenesulfonate  Academic Article
• Oxidation and reduction of 4-hydroxyalkenals catalyzed by isozymes of human alcohol dehydrogenase  Academic Article
• Oxysterols direct immune cell migration via EBI2  Academic Article
• PD 404,182 is a virocidal small molecule that disrupts hepatitis C virus and human immunodeficiency virus  Academic Article
• PD-1 : PD-L1 interactions contribute to the functional suppression of virus-specific CD8(+) T lymphocytes in the liver  Academic Article
• PER1 phosphorylation specifies feeding rhythm in mice  Academic Article
• PU.1 and the granulocyte- and macrophage colony-stimulating factor receptors play distinct roles in late-stage myeloid cell differentiation  Academic Article
• Pancreas-specific delivery of β-cell proliferating small molecules  Academic Article
• Partial purification of the template-active fraction of chromatin: A preliminary report  Academic Article
• Pathogenesis of chronic disease associated with persistent lymphocytic choriomeningitis viral infection. I. Relationship of antibody production to disease in neonatally infected mice  Academic Article
• Pathogenesis of chronic disease associated with persistent lymphocytic choriomeningitis viral infection. Ii. Relationship of the anti-lymphocytic choriomeningitis immune response to tissue injury in chronic lymphocytic choriomeningitis disease  Academic Article
• Pathogenesis of chronic hepatitis C: Immunological features of hepatic injury and viral persistence  Academic Article
• Pathogenic role of B cells in anti-CD40-induced necroinflammatory liver disease  Academic Article
• Pathophysiologic effects of lethal and immunoregulatory doses of cholera enterotoxin in mouse  Academic Article
• Peptide nucleic acids conjugated to short basic peptides show improved pharmacokinetics and antisense activity in adipose tissue  Academic Article
• Peripheral deletion of self-reactive b-cells  Academic Article
• Peroxisome proliferator activated receptor-alpha expression in human liver  Academic Article
• Pharmacokinetics of orally administered camptothecins  Academic Article
• Phosphofructokinase isozyme expression during myoblast differentiation  Academic Article
• Phospshoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) dual inhibitors: discovery and structure-activity relationships of a series of quinoline and quinoxaline derivatives  Academic Article
• Photoaffinity labelling of the active site of the rat glutathione transferases 3-3 and 1-1 and human glutathione transferase A1-1  Academic Article
• Physiological significance of a peripheral tissue circadian clock  Academic Article
• Plasma clearance of bacteriophage Qβ particles as a function of surface charge  Academic Article
• Plasmodium circumsporozoite protein promotes the development of the liver stages of the parasite  Academic Article
• Platelets mediate cytotoxic T lymphocyte-induced liver damage  Academic Article
• Posttranscriptional clearance of hepatitis B virus RNA by cytotoxic T lymphocyte-activated hepatocytes  Academic Article
• Potent antitumor effects of intra-arterial injection of fibroblasts genetically engineered to express IL-12 in liver metastasis model of rat: No additional benefit of using retroviral producer cell  Academic Article
• Preclinical evaluation of an anti-HCV miRNA cluster for treatment of HCV infection  Academic Article
• Preclinical studies for pharmacokinetics and biodistribution of AD-stTRAIL, an adenovirus delivering secretable trimeric trail for gene therapy  Academic Article
• Primary structure of beta-galactoside alpha-2,6-sialyltransferase - conversion of membrane-bound enzyme to soluble forms by cleavage of the nh2-terminal signal anchor  Academic Article
• Primary structure of gal-beta-1,3(4)glcnac alpha-2,3-sialyltransferase determined by mass-spectrometry sequence-analysis and molecular-cloning - evidence for a protein motif in the sialyltransferase gene family  Academic Article
• Product inhibition studies of human liver formaldehyde dehydrogenase  Academic Article
• Production of 2 distinct and independent hepatic immunoregulatory molecules by the perfused rat-liver  Academic Article
• Profiling enzyme activities in vivo using click chemistry methods  Academic Article
• Properties of expressed and native flavin-containing monooxygenases - evidence of multiple forms in rabbit liver and lung  Academic Article
• Proposed reductive metabolism of artemisinin by glutathione transferases in vitro  Academic Article
• Protein malnutrition during pregnancy in c57bl/6j mice results in offspring with altered circadian physiology before obesity  Academic Article
• Proteomics of rat liver Golgi complex: minor proteins are identified through sequential fractionation  Academic Article
• Proteomics reveal a link between the endoplasmic reticulum and lipid secretory mechanisms in mammary epithelial cells  Academic Article
• Pulsed azidohomoalanine labeling in mammals (PALM) detects changes in liver-specific LKB1 knockout mice  Academic Article
• Purification and characterization of cytoplasmic thioltransferase (glutathione:disulfide oxidoreductase) from rat liver  Academic Article
• Purification and characterization of glutathione reductase from calf liver. An improved procedure for affinity chromatography on 2',5'-ADP-Sepharose 4B  Academic Article
• Purification and characterization of pyridoxal 5'-phosphate dependent serine hydroxymethylase from lamb liver and its action upon beta-phenylserines  Academic Article
• Purification and characterization of the flavoenzyme glutathione reductase from rat liver  Academic Article
• Purification and characterization of three distinct glutathione transferases from mouse liver  Academic Article
• Purification and characterization of two glutathione S-aryltransferase activities from rat liver  Academic Article
• Purification and immunological studies of glutathione reductase from rat liver. Evidence for an antigenic determinant at the nucleotide-binding domain of the enzyme  Academic Article
• Purification and properties of rat liver sec23-sec24 complex  Academic Article
• Purification of DT-diaphorase by affinity chromatography. Occurrence of two subunits and nonlinear Dixon and Scatchard plots of the inhibition by anticoagulants  Academic Article
• Purification of a benzo[a]pyrene binding protein by affinity chromatography and photoaffinity labeling  Academic Article
• Purification of a new glutathione S-transferase (transferase mu) from human liver having high activity with benzo(alpha)pyrene-4,5-oxide  Academic Article
• Purification of glutathione S-transferases from rat lung by affinity chromatography. Evidence for an enzyme form absent in rat liver  Academic Article
• Purification of major basic glutathione transferase isoenzymes from rat liver by use of affinity chromatography and fast protein liquid chromatofocusing  Academic Article
• Purification, characterization and kinetic studies of glyoxalase I from rat liver  Academic Article
• Pyrazole inhibitors of HMG-CoA reductase: an attempt to dramatically reduce synthetic complexity through minimal analog re-design  Academic Article
• Pyrethroid activity-based probes for profiling cytochrome P450 activities associated with insecticide interactions  Academic Article
• Quantitative analysis of the peripheral blood cytotoxic T lymphocyte response in patients with chronic hepatitis C virus infection  Academic Article
• Quantitative and selective polymerase chain reaction analysis of highly similar human alpha-class glutathione transferases  Academic Article
• Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice  Academic Article
• Quantitative profiling of initiating ribosomes in vivo  Academic Article
• Quantitative reactivity profiling predicts functional cysteines in proteomes  Academic Article
• Quantitative-analysis of transforming growth-factor-beta-1 messenger-rna in the liver of patients with chronic hepatitis-c - absence of correlation between high-levels and severity of disease  Academic Article
• RCADiA: simple automation platform for comparative multidimensional protein identification technology  Academic Article
• Rab1 interaction with a GM130 effector complex regulates COPII vesicle cis-Golgi tethering  Academic Article
• Rab1b regulates vesicular transport between the endoplasmic-reticulum and successive golgi compartments  Academic Article
• Rabbit hepatic progesterone 21-hydroxylase exhibits a bimodal distribution of activity  Academic Article
• Rabbit pregnane X receptor is activated by rifampicin  Academic Article
• Rabbit prostaglandin omega-hydroxylase (CYP4A4) - gene structure and expression  Academic Article
• RagA, but not RagB, is essential for embryonic development and adult mice  Academic Article
• Rangtp targets p97 to ranbp2, a filamentous protein localized at the cytoplasmic periphery of the nuclear pore complex  Academic Article
• Rat stem cells developing in irradiated scid mice fail to become tolerized and cause lethal graft-versus-host disease  Academic Article
• Reactivation of asialo-rabbit liver binding-protein by resialylation with beta-d-galactoside alpha2- 6 sialyltransferase  Academic Article
• Reactivation of insulin-like growth factor II during hepatocarcinogenesis in transgenic mice suggests a role in malignant growth  Academic Article
• Recognition of bacterial glycosphingolipids by natural killer T cells  Academic Article
• Recombinant duck interferon gamma inhibits duck hepatitis B virus replication in primary hepatocytes  Academic Article
• Redirecting adenovirus to pulmonary endothelium by cationic liposomes  Academic Article
• Reduced cholesterol and triglycerides in mice with a mutation in mia2, a liver protein that localizes to er exit sites  Academic Article
• Reduced hematopoietic reserves in DNA interstrand crosslink repair-deficient ercc1(-/-) mice  Academic Article
• Reduction of disulphide bonds in proteins mixed disulphides catalysed by a thioltransferase in rat liver cytosol  Academic Article
• Reductive decomposition of S-sulfoglutathione in rat liver  Academic Article
• Redundant function of REV-ERBα and β and non-essential role for Bmal1 cycling in transcriptional regulation of intracellular circadian rhythms  Academic Article
• Refined crystal-structure of cd, zn metallothionein at 2.0 a resolution  Academic Article
• Regulated expression of alpha-2,6-sialyltransferase by the liver-enriched transcription factors hnf-1, dbp, and lap  Academic Article
• Regulated expression of the apolipoprotein e/c-i/c-iv/c-ii gene cluster in murine and human macrophages - a critical role for nuclear liver x receptors alpha and beta  Academic Article
• Regulation in-vitro of an l-cam enhancer by homeobox genes hoxd9 and hnf-1  Academic Article
• Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling  Academic Article
• Regulation of carbohydrate metabolism by the farnesoid x receptor  Academic Article
• Regulation of circadian behaviour and metabolism by REV-ERB-alpha and REV-ERB-beta  Academic Article
• Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists  Academic Article
• Regulation of expression of citrate synthase by the retinoic acid receptor-related orphan receptor alpha (ror alpha)  Academic Article
• Regulation of murine type 1 plasminogen activator inhibitor gene expression in vivo. Tissue specificity and induction by lipopolysaccharide, tumor necrosis factor-alpha, and transforming growth factor-beta  Academic Article
• Regulation of the hepatic synthesis of C1 inhibitor by the hepatocyte stimulating factors interleukin-6 and interferon-gamma  Academic Article
• Regulation of the host response to bacterial lipopolysaccharides  Academic Article
• Regulation of the rabbit cytochrome-P-450 3C gene - age-dependent expression and transcriptional activation by rifampicin  Academic Article
• Regulation of tissue factor gene expression in obesity  Academic Article
• Relationship of acetyl transferase activity to antinuclear antibodies and toxic symptoms in hypertensive patients treated with hydralazine  Academic Article
• Relative contributions of thioltransferase-and thioredoxin-dependent systems in reduction of low-molecular-mass and protein disulphides  Academic Article
• Relaxed thiol substrate specificity of glutathione transferase effected by a non-substrate glutathione derivative  Academic Article
• Remote trauma sensitizes hepatic microcirculation to endothelin via caveolin inhibition of eNOS activity  Academic Article
• Removal of the 4,4-dimethyl carbons in the enzymic conversion of lanosterol to cholesterol. Initial loss of the 4-alpha-methyl group  Academic Article
• Resistance of genetically selected mice to MHV3 infection is not dependent on the H2O2 release by macrophages  Academic Article
• Resolution of 2 forms of cytochrome-P-450 from liver-microsomes of rabbits treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin  Academic Article
• Resolution of glutathione-linked enzymes in rat liver and evaluation of their contribution to disulfide reduction via thiol--disulfide interchange  Academic Article
• Retrovirally transduced bone marrow stromal cells isolated from a mouse model of human osteogenesis imperfecta (oim) persist in bone and retain the ability to form cartilage and bone after extended passaging  Academic Article
• Reversibility of hepatitis B virus-induced glomerulonephritis and chronic active hepatitis after spontaneous clearance of serum hepatitis B surface antigen  Academic Article
• Role of aspartate-37 in determining cofactor specificity and binding in rat-liver dihydropteridine reductase  Academic Article
• Role of cytoplasmic thioltransferase in cellular regulation by thiol-disulphide interchange  Academic Article
• Role of homology-directed recombination - predominantly productive rearrangements of H81X in newborns but not in adults  Academic Article
• Role of the host cell's unfolded protein response in arenavirus infection  Academic Article
• Role of thromboxane A(2) in early BDL-induced portal hypertension  Academic Article
• Role of transforming growth factor beta type ii receptor in hepatic fibrosis: Studies of human chronic hepatitis c and experimental fibrosis in rats  Academic Article
• Selected mutants of mouse hepatitis-virus type-4 (jhm-strain) induce different cns diseases - pathobiology of disease induced by wild-type and mutant-ts8 and mutant-ts15 in balb/c and sjl/j mice  Academic Article
• Selective expression of glutathione transferase isoenzymes in chemically induced preneoplastic rat hepatocyte nodules  Academic Article
• Separation of gal-beta-1,4glcnac-alpha-2,6-sialyltransferase and gal-beta-1,3(4)glcnac-alpha-2,3-sialyltransferase by affinity-chromatography  Academic Article
• Separation of glutathione S-transferases from rat liver cytosol by chromatofocusing  Academic Article
• Sepsis induces extensive autophagic vacuolization in hepatocytes: a clinical and laboratory-based study  Academic Article
• Sequence composition of template-active fraction of rat-liver chromatin  Academic Article
• Sequence-analysis of a cdna clone encoding the liver-cell adhesion molecule, l-cam  Academic Article
• Sequence-specific h-1-NMR assignments in rabbit-liver metallothionein-2  Academic Article
• Sequence-specific h-1-NMR assignments in rat-liver metallothionein-2  Academic Article
• Severe endogenous hypertriglyceridemia during treatment with estrogen and oral contraceptives  Academic Article
• Short-term fasting induces profound neuronal autophagy  Academic Article
• Simultaneous detection of hepatitis C virus and interferon stimulated gene expression in infected human liver  Academic Article
• Single-crystals of cadmium, zinc metallothionein  Academic Article
• Single-step purification and h.p.l.c. analysis of glutathione transferase 8-8 in rat tissues  Academic Article
• Small molecule targeting of a microRNA associated with hepatocellular carcinoma  Academic Article
• Soluble transferrin receptor-1 levels in mice do not affect iron absorption  Academic Article
• Specificity of autoantibodies to tubular and glomerular basement membranes induced in guinea pigs  Academic Article
• Sphingosine 1-phosphate regulates regeneration and fibrosis after liver injury via sphingosine 1-phosphate receptor 2  Academic Article
• Squalene-2,3-oxide, an intermediate in the enzymatic conversion of squalene to lanosterol and cholesterol  Academic Article
• Stability, characterization, and kinetics of in-111-labeled monoclonal anti-tumor antibodies in normal animals and nude mouse-human tumor-models  Academic Article
• Steady-state levels of factor-x messenger-rna in liver and hep g2 cells  Academic Article
• Stereochemical outcome of processing of fluorinated substrates by ATP citrate lyase and malate synthase  Academic Article
• Strategies for the design of hepatoselective glucokinase activators to treat type 2 diabetes  Academic Article
• Strong, sustained hepatocellular proliferation precedes hepatocarcinogenesis in hepatitis-B surface-antigen transgenic mice  Academic Article
• Structural and pathological effects of synthesis of hepatitis B virus large envelope polypeptide in transgenic mice  Academic Article
• Structural characterization of a heterogeneous family of rat-brain messenger-rnas  Academic Article
• Structural evidence for three different types of glutathione transferase in human tissues  Academic Article
• Structural studies and isolation of cdna clones providing the complete sequence of rat-liver dihydropteridine reductase  Academic Article
• Structural-analysis of the p62 complex, an assembly of o-linked glycoproteins that localizes near the central gated channel of the nuclear-pore complex  Academic Article
• Structure of the junction between communicating cells  Academic Article
• Structure of transcriptionally active chromatin  Academic Article
• Structure of transcriptionally-active chromatin subunits  Academic Article
• Structure, biosynthesis and functions of glycoprotein glycans  Academic Article
• Structure, distribution, and functional expression of the phosphofructokinase-c isozyme  Academic Article
• Studies of reactions of lamb liver serine hydroxymethylase with l-phenylalanine - kinetic isotope effects upon quinonoid intermediate formation  Academic Article
• Studies of reactions of substituted d,l-erythro-beta-phenylserines with lamb liver serine hydroxymethylase - effects of substituents upon de-aldolization step  Academic Article
• Studies on the reaction mechanism of DT diaphorase. Intermediary plateau and trough regions in the initial velocity vs substrate concentration curves  Academic Article
• Substituted Pyrazoles as hepatoselective HMG-CoA reductase inhibitors: Discovery of (3R,5R)-7-[2-(4-Fluoro-phenyl)-4-isopropyl-5-(4-methyl-benzylcarbamoyl)- 2H-pyrazol-3-yl]-3,5-dihydroxyheptanoic acid (PF-3052334) as a candidate for the treatment of hypercholesterolemia  Academic Article
• Sulfaphenazole derivatives as tools for comparing cytochrome P450 2C5 and human cytochromes P450 2Cs: identification of a new high affinity substrate common to those enzymes  Academic Article
• Suppression of host p53 is critical for Plasmodium liver-stage infection  Academic Article
• Suppression of lymphocyte-activation by a protein released from isolated perfused-rat-liver  Academic Article
• Synergy between hepatitis-B virus expression and chemical hepatocarcinogens in transgenic mice  Academic Article
• Synthesis in vitro of intrinsic membrane proteins by free, membrane-bound, and golgi apparatus-associated polyribosomes from rat-liver  Academic Article
• Synthesis of a mixed disulfide of egg white lysozyme and glutathione - a model substrate for enzymatic reduction of protein mixed disulfides  Academic Article
• Systematic application of high-resolution, phase-sensitive two-dimensional h-1-NMR techniques for the identification of the amino-acid-proton spin systems in proteins - rabbit metallothionein-2  Academic Article
• Systemic blockade of sialylation in mice with a global inhibitor of sialyltransferases  Academic Article
• Systemic immunoregulatory and proteogenomic effects of tacrolimus to sirolimus conversion in liver transplant recipients  Academic Article
• T cell-independent rescue of b lymphocytes from peripheral immune tolerance  Academic Article
• TCR selection and allelic exclusion in RAG transgenic mice that exhibit abnormal T-cell localization in lymph-nodes and lymphatics  Academic Article
• Targeted DNA recombination in vivo using an adenovirus carrying the cre recombinase gene  Academic Article
• Targeted Fcγ receptor (FcγR)-mediated clearance by a biparatopic bispecific antibody  Academic Article
• Targeted delivery of lipid antigen to macrophages via the CD169/sialoadhesin endocytic pathway induces robust invariant natural killer T cell activation  Academic Article
• Targeted disruption of Aldh1a1 (Raldh1) provides evidence for a complex mechanism of retinoic acid synthesis in the developing retina  Academic Article
• Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis  Academic Article
• Tazolol (1-isopropylamino-3-(2-thiazoloxy)-2-propanol) as a beta-adrenergic blocker  Academic Article
• Temporal orchestration of circadian autophagy rhythm by C/EBPβ  Academic Article
• The 4S polycyclic aromatic hydrocarbon-binding protein: immunohistochemical localization in mice  Academic Article
• The NMR solution structure of the non-classical homeodomain from the rat liver lfb1/hnf1 transcription factor  Academic Article
• The Plasmodium eukaryotic initiation factor-2alpha kinase IK2 controls the latency of sporozoites in the mosquito salivary glands  Academic Article
• The activities of current antimalarial drugs on the life cycle stages of plasmodium: A comparative study with human and rodent parasites  Academic Article
• The amount and nature of glutathione transferases in rat liver microsomes determined by immunochemical methods  Academic Article
• The binding of substrates and a product of the enzymatic reaction to glutathione S-transferase A  Academic Article
• The cancer drug dasatinib increases PGC-1α in adipose tissue but has adverse effects on glucose tolerance in obese mice  Academic Article
• The class I-restricted cytotoxic T lymphocyte response to predetermined epitopes in the hepatitis B and C viruses  Academic Article
• The clearance, tissue distribution, and cellular localization of intravenously injected lipopolysaccharide in rabbits  Academic Article
• The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs  Academic Article
• The design and synthesis of a potent glucagon receptor antagonist with favorable physicochemical and pharmacokinetic properties as a candidate for the treatment of type 2 diabetes mellitus  Academic Article
• The effect of ethanol on the steady-state kinetics of glutathione S-transferase A from rat liver  Academic Article
• The half-life of hepatitis B virions  Academic Article
• The hepatitis B virus X protein transactivates viral core gene expression in vivo  Academic Article
• The hepatoselective glucokinase activator PF-04991532 ameliorates hyperglycemia without causing hepatic steatosis in diabetic rats  Academic Article
• The immunology of liver microsomes. I. The properties of the quantitative precipitin system  Academic Article
• The immunology of liver microsomes. II. Immunological relations of the microsomes to other cell fractions  Academic Article
• The immunology of liver microsomes. III. The localization of tissue-specific antigens within the structural components of endoplastic reticulum  Academic Article
• The immunopathogenesis of chronic HBV induced liver-disease  Academic Article
• The importance of tissue substrate in the SS-A/Ro antigen-antibody system  Academic Article
• The induction of a unique procoagulant activity in rabbit hepatic macrophages by bacterial lipopolysaccharides  Academic Article
• The influence of T cell subsets on Trypanosoma cruzi multiplication in different organs  Academic Article
• The inv(16) cooperates with arf haploinsufficiency to induce acute myeloid leukemia  Academic Article
• The kidneys of mice with autoimmune disease acquire a hypofibrinolytic/procoagulant state that correlates with the development of glomerulonephritis and tissue microthrombosis  Academic Article
• The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin  Academic Article
• The length of nucleosome-associated DNA is same in both transcribed and nontranscribed regions of chromatin  Academic Article
• The lipopolysaccharide-binding protein is a secretory class 1 acute-phase protein whose gene is transcriptionally activated by aprf/stat-3 and other cytokine-inducible nuclear proteins  Academic Article
• The membrane-binding domain of a rat-liver golgi sialyltransferase  Academic Article
• The methionine transamination pathway controls hepatic glucose metabolism through regulation of the GCN5 acetyltransferase and the PGC-1α transcriptional coactivator  Academic Article
• The nature of the enzymatic reduction of S-sulfoglutathione in liver and peas  Academic Article
• The nature of the enzymatic reduction of the mixed disulfide of coenzyme A and glutathione  Academic Article
• The nuclear receptor lxr is a glucose sensor  Academic Article
• The ovalbumin gene. Partial purification of the coding strand  Academic Article
• The oxidative DNA lesions 8,5'-cyclopurines accumulate with aging in a tissue-specific manner  Academic Article
• The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis  Academic Article
• The pathobiology of viral-hepatitis and immunological activation of the coagulation protease network  Academic Article
• The receptor for trans-epithelial transport of iga and igm contains multiple immunoglobulin-like domains  Academic Article
• The response of isolated rabbit hepatic macrophages (h-mo) to lipopolysaccharide (lps)  Academic Article
• The role of IFN regulatory factor-1 in synovitis and nitric oxide production  Academic Article
• The role of afferent blood supply in regeneration of liver isografts in rats  Academic Article
• The role of cytosolic proteins in the intracellular-transport of heme in rat-liver - a dual-label approach  Academic Article
• The serine hydrolase ABHD6 Is a critical regulator of the metabolic syndrome  Academic Article
• The signal anchor and stem regions of the beta-galactoside alpha-2,6-sialyltransferase may each act to localize the enzyme to the golgi-apparatus  Academic Article
• The size of the viral inoculum contributes to the outcome of hepatitis B virus infection  Academic Article
• The stereochemistry of pyridoxal phosphate enzymes. The absolute stereochemistry of cofactor c' 4 protonation in the transamination of holoserine hydroxymethylase by d-alanine  Academic Article
• The three-dimensional NMR-solution structure of the polypeptide fragment 195-286 of the LFB1/HNF1 transcription factor from rat liver comprises a nonclassical homeodomain  Academic Article
• The trans-stilbene oxide-active glutathione transferase in human mononuclear leucocytes is identical with the hepatic glutathione transferase mu  Academic Article
• The transcriptional repressor STRA13 regulates a subset of peripheral circadian outputs  Academic Article
• Three-dimensional structure of gap junctions in fragmented plasma membranes from rat liver  Academic Article
• Three-dimensional structure of rabbit liver [Cd7]metallothionein-2a in aqueous solution determined by nuclear magnetic resonance  Academic Article
• Thrombin-activatable fibrinolysis inhibitor (tafi, plasma procarboxypeptidase b, procarboxypeptidase r, procarboxypeptidase u)  Academic Article
• Thyroxine-dependent modulations of the expression of the neural cell-adhesion molecule n-cam during xenopus-laevis metamorphosis  Academic Article
• Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression  Academic Article
• Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet  Academic Article
• Tissue distribution and regulation of murine von Willebrand factor gene expression in vivo  Academic Article
• Tissue distribution of factor VIII gene expression in vivo: a closer look  Academic Article
• Tissue-specific alternative splicing of the beta-galactoside alpha-2,6-sialyltransferase gene  Academic Article
• Tissue-specific expression of sialyltransferases  Academic Article
• Tissue-specific regulation of p38α-mediated inflammation in Con A-induced acute liver damage  Academic Article
• ToP-DNJ, a selective inhibitor of endoplasmic reticulum α-glucosidase II Exhibiting Antiflaviviral Activity  Academic Article
• Toll-like receptor signaling inhibits hepatitis B virus replication in vivo  Academic Article
• Toxicogenomics and metabolomics of pentamethylchromanol (PMCol)-induced hepatotoxicity  Academic Article
• Toxicokinetics of chloral hydrate in ad libitum-fed, dietary-controlled, and calorically restricted male B6C3F(1) mice following short-term exposure  Academic Article
• Tpr, a large coiled-coil protein whose amino-terminus is involved in activation of oncogenic kinases, is localized to the cytoplasmic surface of the nuclear-pore complex  Academic Article
• Transcriptional and posttranscriptional control of hepatitis B virus gene expression  Academic Article
• Transfer of dysbiotic gut microbiota has beneficial effects on host liver metabolism  Academic Article
• Transfer of synthetic sialic-acid analogs to n-linked and o-linked glycoprotein glycans using 4 different mammalian sialytransferases  Academic Article
• Transformation and insertional mutagenesis in vitro of primary hematopoietic stem cell cultures  Academic Article
• Transformation of leukotriene A4 methyl ester to leukotriene C4 monomethyl ester by cytosolic rat glutathione transferases  Academic Article
• Transmission of type B viral hepatitis to chimpanzees  Academic Article
• Transplantation antigens  Academic Article
• Tropomodulin3-null mice are embryonic lethal with anemia due to impaired erythroid terminal differentiation in the fetal liver  Academic Article
• Tumor necrosis factor-alpha and interleukin-1 beta production by human fetal Kupffer cells  Academic Article
• Two configurations of a channel-forming membrane protein  Academic Article
• Two distinct forms of glutathione transferase from human foetal liver. Purification and comparison with isoenzymes isolated from adult liver and placenta  Academic Article
• Two forms of isolated gap junctions  Academic Article
• Type 1 plasminogen activator inhibitor gene expression following partial hepatectomy  Academic Article
• Unacylated ghrelin rapidly modulates lipogenic and insulin signaling pathway gene expression in metabolically active tissues of GHSR deleted mice  Academic Article
• Undesired versus designed enzymatic cleavage of linkers for liver targeting  Academic Article
• V-beta repertoire of murine hepatic T-cells - implication for selection of double-negative alpha-beta(+) T-cells  Academic Article
• VLDL hydrolysis by hepatic lipase regulates PPARδ transcriptional responses  Academic Article
• Variants able to cause growth hormone deficiency syndrome are present within the disease-nil WE strain of lymphocytic choriomeningitis virus  Academic Article
• Vascular gene transfer of the human inducible nitric oxide synthase: Characterization of activity and effects on myointimal hyperplasia  Academic Article
• Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease  Academic Article
• Viral clearance without destruction of infected cells during acute HBV infection  Academic Article
• Viral cross talk: Intracellular inactivation of the hepatitis B virus during an unrelated viral infection of the liver  Academic Article
• Vitronectin gene expression in vivo. Evidence for extrahepatic synthesis and acute phase regulation  Academic Article
• Voronoi binding site model of a polycyclic aromatic hydrocarbon binding protein  Academic Article
• Why are some amyloidoses systemic? Does hepatic "chaperoning at a distance" prevent cardiac deposition in a transgenic model of human senile systemic (transthyretin) amyloidosis?  Academic Article
• X-ray absorption studies of the copper-beta domain of rat-liver metallothionein  Academic Article
• X-ray structure of metallothionein  Academic Article
• Zebrafish as a genetic model in biological and behavioral gerontology: where development meets aging in vertebrates. A mini-review  Academic Article
• cDNA cloning and analysis of the expression of nucleoporin p45  Academic Article