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Lens, Crystalline

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  • A Gja8 (Cx50) point mutation causes an alteration of α3 connexin (Cx46) in semi-dominant cataracts of Lop10 mice  Academic Article
  • Absence of alpha3 (Cx46) and alpha8 (Cx50) connexins leads to cataracts by affecting lens inner fiber cells  Academic Article
  • Analysis of tryptic peptides from the C-terminal region of alpha-crystallin from cataractous and normal human lenses  Academic Article
  • Arginine 54 and tyrosine 118 residues of αA-crystallin are crucial for lens formation and transparency  Academic Article
  • Bfsp2 mutation found in mouse 129 strains causes the loss of CP49 and induces vimentin-dependent changes in the lens fibre cell cytoskeleton  Academic Article
  • Bmp signaling is required for development of primary lens fiber cells  Academic Article
  • Caspase remodeling of the spectrin membrane skeleton during lens development and aging  Academic Article
  • Cataracts and microphthalmia caused by a Gja8 mutation in extracellular loop 2  Academic Article
  • Cell-adhesion molecules in early chicken embryogenesis  Academic Article
  • Comparative-analysis of the major polypeptides from liver gap-junctions and lens fiber junctions  Academic Article
  • Connections between connexins, calcium, and cataracts in the lens  Academic Article
  • Connexin 50 regulates surface ball-and-socket structures and fiber cell organization  Academic Article
  • Connexin mediated cataract prevention in mice  Academic Article
  • Connexins in lens development and cataractogenesis  Academic Article
  • Crystallin gamma B-I4F mutant protein binds to alpha-crystallin and affects lens transparency  Academic Article
  • Development of cataractous macrophthalmia in mice expressing an active MEK1 in the lens  Academic Article
  • Disruption of Gja8 (α8 connexin) in mice leads to microphthalmia associated with retardation of lens growth and lens fiber maturation  Academic Article
  • Disruption of α3 connexin gene leads to proteolysis and cataractogenesis in mice  Academic Article
  • Diverse gap junctions modulate distinct mechanisms for fiber cell formation during lens development and cataractogenesis  Academic Article
  • Diverse roles of Eph/ephrin signaling in the mouse lens  Academic Article
  • Dominant cataracts result from incongruous mixing of wild-type lens connexins  Academic Article
  • EPHA2 is associated with age-related cortical cataract in mice and humans  Academic Article
  • Enhancement of ubiquitin conjugation activity reduces intracellular aggregation of V76D mutant gammaD-crystallin  Academic Article
  • EphA2 and Src regulate equatorial cell morphogenesis during lens development  Academic Article
  • EphA2 and ephrin-A5 are not a receptor-ligand pair in the ocular lens  Academic Article
  • Fgf receptor signaling plays a role in lens induction  Academic Article
  • Gap junction communication influences intercellular protein distribution in the lens  Academic Article
  • Gap junctional coupling in lenses from α(8) connexin knockout mice  Academic Article
  • Gap junctional coupling in lenses lacking alpha(3) connexin  Academic Article
  • Genetic factors influence cataract formation in α(3) connexin knockout mice  Academic Article
  • Growth of hollow cell spheroids in microbead templated chambers  Academic Article
  • Identification and characterization of tropomodulin and tropomyosin in the adult rat lens  Academic Article
  • Interaction between Connexin50 and mitogen-activated protein kinase signaling in lens homeostasis  Academic Article
  • Knock-in of α3 connexin prevents severe cataracts caused by an α8 point mutation  Academic Article
  • Lens gap junctions in growth, differentiation, and homeostasis  Academic Article
  • Lens ion homeostasis relies on the assembly and/or stability of large connexin 46 gap junction plaques on the broad sides of differentiating fiber cells  Academic Article
  • Mechanism of cataract formation in alpha A-crystallin Y118D mutation  Academic Article
  • Misexpression of IGF-I in the mouse lens expands the transitional zone and perturbs lens polarization  Academic Article
  • Modulation of N-cadherin junctions and their role as epicenters of differentiation-specific actin regulation in the developing lens  Academic Article
  • Ostrich crystallins. Structural characterization of delta-crystallin with enzymic activity  Academic Article
  • Sequence comparison of gamma-crystallins from the reptilian and other vertebrate species  Academic Article
  • Shotgun identification of protein modifications from protein complexes and lens tissue  Academic Article
  • Stabilization and remodeling of the membrane skeleton during lens fiber cell differentiation and maturation  Academic Article
  • Structural and immunocytochemical alterations in eye lens fiber cells from Cx46 and Cx50 knockout mice  Academic Article
  • The cataract causing Cx50-S50P mutant inhibits Cx43 and intercellular communication in the lens epithelium  Academic Article
  • The cataract-inducing S50P mutation in Cx50 dominantly alters the channel gating of wild-type lens connexins  Academic Article
  • The interaction and phosphorylation of tropomodulin by protein kinase C alpha in N/N 1003A lens epithelial cells  Academic Article
  • The lens membrane skeleton contains structures preferentially enriched in spectrin-actin or tropomodulin-actin complexes  Academic Article
  • The upstream ectoderm enhancer in Pax6 has an important role in lens induction  Academic Article
  • Tmod1 and CP49 synergize to control the fiber cell geometry, transparency, and mechanical stiffness of the mouse lens  Academic Article
  • Tropomodulin 1 constrains fiber cell geometry during elongation and maturation in the lens cortex  Academic Article
  • Tropomodulin and tropomyosin mediate lens cell actin cytoskeleton reorganization in vitro  Academic Article
  • Tropomodulin binds to filensin intermediate filaments  Academic Article
  • Tropomodulin1 is required for membrane skeleton organization and hexagonal geometry of fiber cells in the mouse lens  Academic Article
  • Vitrectomy and scleral buckling methods for proliferative vitreoretinopathy  Academic Article
  • γD-crystallin-associated protein aggregation and lens fiber cell denucleation  Academic Article

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