subject area of
- A chemical approach for detecting sulfenic acid-modified proteins in living cells Academic Article
- Activation of pro-uPA is critical for initial escape from the primary tumor and hematogenous dissemination of human carcinoma cells Academic Article
- Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations Academic Article
- Amide proton-exchange and surface conformation of the basic pancreatic trypsin-inhibitor in solution - studies with two-dimensional nuclear magnetic-resonance Academic Article
- Amide proton-exchange in proteins by ex1 kinetics - studies of the basic pancreatic trypsin-inhibitor at variable p2h and temperature Academic Article
- Amide-proton exchange studies by 2-dimensional correlated h-1-NMR in 2 chemically modified analogs of the basic pancreatic trypsin-inhibitor Academic Article
- An evaluation of the combined use of nuclear magnetic-resonance and distance geometry for the determination of protein conformations in solution Academic Article
- Aprotinin (trasylol) is a competitive inhibitor of activated protein-C Academic Article
- C-13 nuclear magnetic-resonance relaxation studies of internal mobility of the polypeptide-chain in basic pancreatic trypsin-inhibitor and a selectively reduced analog Academic Article
- C-13 nuclear magnetic-resonance studies of the selectively isotope-labeled reactive site peptide-bond of the basic pancreatic trypsin-inhibitor in the complexes with trypsin, trypsinogen, and anhydrotrypsin Academic Article
- Calibration of the angular-dependence of the amide proton-c-alpha proton coupling-constants, 3jhn-alpha, in a globular protein - use of 3jhn-alpha for identification of helical secondary structure Academic Article
- Chemical modification of bovine pancreatic trypsin inhibitor for single site coupling of immunogenic peptides for NMR conformational analysis Academic Article
- Comparative studies of conformation and internal mobility in native and circular basic pancreatic trypsin-inhibitor by h-1 nuclear magnetic-resonance in solution Academic Article
- Conformational sampling by NMR solution structures calculated with the program diana evaluated by comparison with long-time molecular dynamics calculations in explicit water Academic Article
- Conformational studies by h-1 nuclear magnetic-resonance of the basic pancreatic trypsin-inhibitor after reduction of the disulfide bond between cys-14 and cys-38 - influence of charged protecting groups on the stability of the protein Academic Article
- Designed replacement of an internal hydration water molecule in bpti - structural and functional implications of a glycine-to-serine mutation Academic Article
- Determination of a high-quality nuclear-magnetic-resonance solution structure of the bovine pancreatic trypsin-inhibitor and comparison with 3 crystal-structures Academic Article
- Disulfide bond isomerization in bpti and bpti(g36s) - an NMR-study of correlated mobility in proteins Academic Article
- Dynamics of aromatic amino-acid residues in globular conformation of basic pancreatic trypsin-inhibitor (bpti) .1. H-1 NMR-studies Academic Article
- Dynamics of aromatic amino-acid residues in globular conformation of basic pancreatic trypsin-inhibitor (bpti) .2. Semiempirical energy calculations Academic Article
- Engineering an unnatural N-alpha-anchored disulfide into BPTI by total chemical synthesis: structural and functional consequences Academic Article
- H-1 NMR-studies at 360 mhz of methyl-groups in native and chemically modified basic pancreatic trypsin-inhibitor (bpti) Academic Article
- High-field c-13 NMR-studies at 90.5 mhz of methyl-groups in basic pancreatic trypsin-inhibitor Academic Article
- High-field c-13 nuclear magnetic-resonance studies at 90.5 mhz of basic pancreatic trypsin-inhibitor Academic Article
- Hydration of biological macromolecules in solution - surface-structure and molecular recognition Academic Article
- Hydration of proteins - a comparison of experimental residence times of water-molecules solvating the bovine pancreatic trypsin-inhibitor with theoretical-model calculations Academic Article
- Individual amide proton exchange rates in thermally unfolded basic pancreatic trypsin inhibitor Academic Article
- Individual assignments of amide proton resonances in the proton NMR-spectrum of the basic pancreatic trypsin-inhibitor Academic Article
- Individual assignments of methyl resonances in h-1 nuclear magnetic-resonance spectrum of basic pancreatic trypsin-inhibitor Academic Article
- Influence of a single salt bridge on static and dynamic features of globular solution conformation of basic pancreatic trypsin-inhibitor - h-1 and c-13 NMR-studies of native and transaminated inhibitor Academic Article
- Influence of localized chemical modifications of the basic pancreatic trypsin-inhibitor on static and dynamic aspects of the molecular-conformation in solution Academic Article
- Internal mobility of the basic pancreatic trypsin-inhibitor in solution - a comparison of NMR spin relaxation measurements and molecular-dynamics simulations Academic Article
- Molmol: A program for display and analysis of macromolecular structures Academic Article
- Monitoring of hemostasis parameters during coronary thrombolysis with recombinant tissue-type plasminogen-activator Academic Article
- Nmr-spectroscopy of hydroxyl protons in aqueous-solutions of peptides and proteins Academic Article
- Plasma prekallikrein: Isolation, characterization, and mechanism of activation Academic Article
- Polypeptide secondary structure determination by nuclear magnetic-resonance observation of short proton proton distances Academic Article
- Protein conformation and proton nuclear-magnetic-resonance chemical shifts Academic Article
- Protein dynamics studied by rotating frame n-15 spin relaxation-times Academic Article
- Protein hydration in aqueous-solution Academic Article
- Protein structures in solution by nuclear-magnetic-resonance and distance geometry - the polypeptide fold of the basic pancreatic trypsin-inhibitor determined using 2 different algorithms, disgeo and disman Academic Article
- Pyroglutamyl-aprotinin, a new aprotinin homolog from bovine lungs - isolation, properties, sequence-analysis and characterization using hydrogen nuclear magnetic-resonance in solution Academic Article
- Sequential resonance assignments in protein h-1 nuclear magnetic-resonance spectra - basic pancreatic trypsin-inhibitor Academic Article
- Simultaneous refinement of the structure of bpti against NMR data measured in solution and x-ray-diffraction data measured in single-crystals Academic Article
- Structural interpretation of vicinal proton-proton coupling-constants 3jh-alpha-h-beta in the basic pancreatic trypsin-inhibitor measured by two-dimensional j-resolved NMR-spectroscopy Academic Article
- Structure and internal dynamics of the bovine pancreatic trypsin-inhibitor in aqueous-solution from long-time molecular-dynamics simulations Academic Article
- Studies of j-connectivities and selective h-1-h-1 overhauser effects in h2o solutions of biological macromolecules by two-dimensional NMR experiments Academic Article
- Systematic application of two-dimensional h-1-NMR techniques for studies of proteins .1. Combined use of spin-echo-correlated spectroscopy and j-resolved spectroscopy for the identification of complete spin systems of non-labile protons in amino-acid-residues Academic Article
- Systematic application of two-dimensional h-1-NMR techniques for studies of proteins .2. Combined use of correlated spectroscopy and nuclear overhauser spectroscopy for sequential assignments of backbone resonances and elucidation of polypeptide secondary structures Academic Article
- Texture mapping parametric molecular surfaces Academic Article
- Two-dimensional 1H NMR of two chemically modified analogs of the basic pancreatic trypsin inhibitor. Sequence-specific resonance assignments and sequence location of conformation changes relative to the native protein Academic Article