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Isomerism

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  • A complex equilibrium among partially unfolded conformations in monomeric transthyretin  Academic Article
  • A conformational transition at the n terminus of the prion protein features in formation of the scrapie isoform  Academic Article
  • A light controlled cavitand wall regulates guest binding  Academic Article
  • A rigid trans-spanning dinitrile ligand  Academic Article
  • A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth  Academic Article
  • A synthesis of echinopine B  Academic Article
  • Altered retinoid homeostasis catalyzed by a nicotine metabolite: Implications in macular degenerationand and normal development  Academic Article
  • Alternative conformations of a nucleic acid four-way junction  Academic Article
  • Antibody catalysis of a disfavored chemical transformation  Academic Article
  • Antibody catalysis of peptidyl-prolyl cis-trans isomerization in the folding of RNase T1  Academic Article
  • Antibody modeling assessment II. Structures and models  Academic Article
  • Anticipatory active-site motions and chromophore distortion prime photoreceptor PYP for light activation  Academic Article
  • Application of affinity selection/mass spectrometry to determine the structural isomer of parnafungins responsible for binding polyadenosine polymerase  Academic Article
  • Association of an isomeric species of carcinoembryonic antigen with neoplasia of gastrointestinal-tract  Academic Article
  • Atomistic simulation study of linear alkylbenzene sulfonates at the water/air interface  Academic Article
  • Base-pairing properties of a structural isomer of glycerol nucleic acid  Academic Article
  • Binding and inactivation mechanism of a humanized fatty acid amide hydrolase by alpha-ketoheterocycle inhibitors revealed from cocrystal structures  Academic Article
  • Chemical requirements for inhibition of gap junction communication by the biologically active lipid oleamide  Academic Article
  • Chemical tools for studying the impact of cis/trans prolyl isomerization on signaling: a case study on RNA polymerase II phosphatase activity and specificity  Academic Article
  • Chemical tools to decipher regulation of phosphatases by proline isomerization on eukaryotic RNA polymerase II  Academic Article
  • Cis-unsaturated fatty-acids specifically inhibit a signal-transducing protein-kinase required for initiation of sporulation in bacillus-subtilis  Academic Article
  • Coencapsulation of three different guests in a cylindrical host  Academic Article
  • Comparison of NMR and crystal structures highlights conformational isomerism in protein active sites  Academic Article
  • Conformational isomerism can limit antibody catalysis  Academic Article
  • Contrasting two- and three-dimensional crystal properties of isomeric dialkyl phthalates  Academic Article
  • Crossover isomer bias is the primary sequence-dependent property of immobilized holliday junctions  Academic Article
  • Crystallographic structures of Discosoma red fluorescent protein with immature and mature chromophores: Linking peptide bond trans-cis isomerization and acylimine formation in chromophore maturation  Academic Article
  • Cyclic marinopyrrole derivatives as disruptors of Mcl-1 and Bcl-x(L) binding to Bim  Academic Article
  • DEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A  Academic Article
  • DFT calculations of isomer shifts and quadrupole splitting parameters in synthetic iron-oxo complexes: applications to methane monooxygenase and ribonucleotide reductase  Academic Article
  • DNA-encoded solid-phase synthesis: encoding language design and complex oligomer library synthesis  Academic Article
  • Differential expression of tgf-beta isoforms by human articular chondrocytes in response to growth-factors  Academic Article
  • Differential solvation and tautomer stability of a model base pair within the minor and major grooves of DNA  Academic Article
  • Directed evolution of a bright near-infrared fluorescent rhodopsin using a synthetic chromophore  Academic Article
  • Disulfide isomerization switches tissue factor from coagulation to cell signaling  Academic Article
  • Electrophoretic polymorphism of glutathione peroxidase  Academic Article
  • Electrostatic calculations of side-chain pk(a) values in myoglobin and comparison with NMR data for histidines  Academic Article
  • Elemental isomerism: A boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands  Academic Article
  • Empirical Guidelines for the Development of Remote Directing Templates through Quantitative and Experimental Analyses  Academic Article
  • Enantioselective total synthesis of (-)-napyradiomycin A1 via asymmetric chlorination of an isolated olefin  Academic Article
  • Enzymatic and cryoreduction EPR studies of the hydroxylation of methylated N(ω)-hydroxy-L-arginine analogues by nitric oxide synthase from Geobacillus stearothermophilus  Academic Article
  • Enzymatic catalysis in organic-synthesis  Academic Article
  • Evidence for 2 interconverting protein isomers in the methotrexate complex of dihydrofolate-reductase from escherichia-coli  Academic Article
  • Evolutionarily distinct classes of s27 ribosomal proteins with differential mrna expression in rat hypothalamus  Academic Article
  • Experimental and DFT studies: novel structural modifications greatly enhance the solvent sensitivity of live cell imaging dyes  Academic Article
  • Extended covalent containers: synthesis and guest encapsulation  Academic Article
  • Folding of peptide fragments comprising the complete sequence of proteins. Models for initiation of protein folding. II. Plastocyanin  Academic Article
  • Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation  Academic Article
  • Glutathione conjugation of trans-3,4-dihydroxy 1,2-epoxy 1,2,3,4-tetrahydrobenzo[c]phenanthrene isomers by human glutathione transferases  Academic Article
  • High-throughput evaluation of relative cell permeability between peptoids and peptides  Academic Article
  • Impact of sugar stereochemistry on natural killer T cell stimulation by bacterial glycolipids  Academic Article
  • Individual solvent/solute interactions through social isomerism  Academic Article
  • Interaction of colchicine and some related alkaloids with rat-brain tubulin  Academic Article
  • Isomeric constellations of encapsulation complexes store information on the nanometer scale  Academic Article
  • Isomerization of Δ5-androstene-3,17-dione into Δ4-androstene-3,17-dione catalyzed by human glutathione transferase A3-3: a computational study identifies a dual role for glutathione  Academic Article
  • Light signal transduction in higher plants  Academic Article
  • Mechanism, reactivity, and selectivity of nickel-catalyzed [4 + 4 + 2] cycloadditions of dienes and alkynes  Academic Article
  • Mechanistic studies on the Cu-catalyzed three-component reactions of sulfonyl azides, 1-alkynes and amines, alcohols, or water: dichotomy via a common pathway  Academic Article
  • Metal substitution in the active site of nitrogenase MFe7S9 (M = Mo(4+), V(3+), Fe(3+))  Academic Article
  • Modification of DNA dynamics by platinum drug-binding - a time-dependent fluorescence depolarization study of the interaction of cis-diamminedichloroplatinum (ii) and trans-diamminedichloroplatinum(ii) with DNA  Academic Article
  • Molecular characterization and expression of cloned human galanin receptors GALR2 and GALR3  Academic Article
  • Olfactory learning deficits in mutants for leonardo, a Drosophila gene encoding a 14-3-3 protein  Academic Article
  • Optimization of the central heterocycle of alpha-ketoheterocycle inhibitors of fatty acid amide hydrolase  Academic Article
  • Organocatalytic synthesis of spiro[pyrrolidin-3,3'-oxindoles] with high enantiopurity and structural diversity  Academic Article
  • Peptide backbone sampling convergence with the adaptive biasing force algorithm  Academic Article
  • Peptide synthesis with carbodiimide. III. Racemization  Academic Article
  • Photoisomerization and proton transfer in photoactive yellow protein  Academic Article
  • Picometer-scale conformational heterogeneity separates functional from nonfunctional states of a photoreceptor protein  Academic Article
  • Purification and characterization of an alpha 1 beta 2 isoform of CapZ from human erythrocytes: cytosolic location and inability to bind to Mg2+ ghosts suggest that erythrocyte actin filaments are capped by adducin  Academic Article
  • Regioselective reactions for programmable resveratrol oligomer synthesis  Academic Article
  • Reinforcing effect of pseudoephedrine isomers and the mechanism of action  Academic Article
  • Rhodium-catalyzed asymmetric enyne cycloisomerization of terminal alkynes and formal total synthesis of (-)-platensimycin  Academic Article
  • Rhodium-catalyzed transannulation of 1,2,3-triazoles with nitriles  Academic Article
  • Scalable, enantioselective synthesis of germacrenes and related sesquiterpenes inspired by terpene cyclase phase logic  Academic Article
  • Selective guest exchange in encapsulation complexes using light of different wavelenghts  Academic Article
  • Selective perhydroxylation of squalene - taming the arithmetic demon  Academic Article
  • Social isomers of picolines in a small space  Academic Article
  • Stereocontrolled total synthesis of apicularen a and its delta(17,18) z isomer  Academic Article
  • Structural basis for differential recognition of phosphohistidine-containing peptides by 1-pHis and 3-pHis monoclonal antibodies  Academic Article
  • Structural basis for featuring of steroid isomerase activity in alpha class glutathione transferases  Academic Article
  • Structural basis for high-affinity peptide inhibition of human Pin1  Academic Article
  • Structure of a protein photocycle intermediate by millisecond time-resolved crystallography  Academic Article
  • Structure of the I-1 early intermediate of photoactive yellow protein by FTIR spectroscopy  Academic Article
  • Structure of the human histamine h(1) receptor complex with doxepin  Academic Article
  • Synthesis and applications of Hajos-Parrish ketone isomers  Academic Article
  • Synthesis and characterization of oligonucleotides containing 2 '-fluorinated thymidine glycol as inhibitors of the endonuclease iii reaction  Academic Article
  • Synthesis of 7-aza-5-deazapurine analogues via copper(i)-catalyzed hydroamination of alkynes and 1-iodoalkynes  Academic Article
  • The effect of crystal packing on oligonucleotide double helix structure  Academic Article
  • The formation of metal octamethyltetrabenzoporphyrins from isoindole precursors  Academic Article
  • The incorporation of a photoisomerizable amino acid into proteins in E. coli  Academic Article
  • The isomerization of Delta(5)-androstene-3,17-dione catalyzed by human glutathione transferase A1-1  Academic Article
  • The lef-1 high-mobility group domain undergoes a disorder-to-order transition upon formation of a complex with cognate DNA  Academic Article
  • The stereochemistry of pyridoxal phosphate enzymes. The absolute stereochemistry of cofactor c' 4 protonation in the transamination of holoserine hydroxymethylase by d-alanine  Academic Article
  • Thermodynamics, kinetics, and photochromism of oaklins: a recent family of deoxyanthocyanidins  Academic Article
  • Thermolysis of isomigrastatin and its congeners via 3,3 -sigmatropic rearrangement: A new route to the synthesis of migrastatin and its analogues  Academic Article
  • Thin filaments elongate from their pointed ends during myofibril assembly in Drosophila indirect flight muscle  Academic Article
  • Total synthesis and evaluation of iso-duocarmycin SA and iso-yatakemycin  Academic Article
  • Total synthesis of floresolide B and Δ6,7-Z-floresolide B  Academic Article
  • Total synthesis of platensimycin and related natural products  Academic Article
  • Total synthesis of the calphostins: application of Fischer carbene complexes and thermodynamic control of atropisomers  Academic Article
  • Towards the synthesis of a Yersinia pestis cell wall polysaccharide: enantioselective synthesis of an L-glycero-D-manno-heptose building block  Academic Article
  • Voltage-dependent behavior of a ''ball-and-chain'' gramicidin channel  Academic Article

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