subject area of
- A 46-nucleotide promoter segment from an IFN-alpha gene renders an unrelated promoter inducible by virus Academic Article
- A Jekyll and Hyde profile: Type 1 interferon signaling plays a prominent role in the initiation and maintenance of a persistent virus infection Academic Article
- A novel, quantitative bioassay for type I interferon using a recombinant indicator cell line Academic Article
- A recombinant human enzyme for enhanced interstitial transport of therapeutics Academic Article
- Alpha and beta type 1 interferon signaling: passage for diverse biologic outcomes Academic Article
- Altered tissue distribution of viral replication and t-cell spreading is pivotal in the protection against fatal lymphocytic choriomeningitis in mice after neutralization of ifn-alpha/beta Academic Article
- An IRF-3-, IRF-5-, and IRF-7-independent pathway of dengue viral resistance utilizes IRF-1 to stimulate type I and II interferon responses Academic Article
- Analysis of the MCMV resistome by ENU mutagenesis Academic Article
- Arenavirus nucleoproteins prevent activation of nuclear factor kappa b Academic Article
- Bone marrow plasmacytoid dendritic cells can differentiate into myeloid dendritic cells upon virus infection Academic Article
- Cachectin tumor necrosis factor stimulates collagenase and prostaglandin-e2 production by human synovial-cells and dermal fibroblasts Academic Article
- Cd14 is required for myd88-independent lps signaling Academic Article
- Clinical-trial of natural alpha interferon in multiple-sclerosis Academic Article
- Constitutive, long-term production of human interferons by hamster-cells containing multiple copies of a cloned interferon gene Academic Article
- Cytotoxic T lymphocyte responsiveness after resolution of chronic hepatitis B virus infection Academic Article
- D471G mutation in LCMV-NP affects its ability to self-associate and results in a dominant negative effect in viral RNA synthesis Academic Article
- Deficient signaling in mice devoid of double-stranded rna-dependent protein kinase Academic Article
- Different pathways mediate virus inducibility of the human ifn-alpha-1 and ifn-beta genes Academic Article
- Differential expression of human interferon genes Academic Article
- Differential inhibition of type I interferon induction by arenavirus nucleoproteins Academic Article
- Effects of recombinant human interferons on rheumatoid-arthritis lymphocytes-B activated by Epstein-Barr-virus Academic Article
- Efficient t cell activation via a toll-interleukin 1 receptor-independent pathway Academic Article
- Enhanced antibacterial potential in UBP43-deficient mice against Salmonella typhimurium infection by up-regulation type IIFN signaling Academic Article
- Epstein-Barr-virus complement C3d receptor is an interferon-alpha receptor Academic Article
- Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus Academic Article
- Formation of genes-coding for hybrid proteins by recombination between related, cloned genes in escherichia-coli Academic Article
- Hepatitis C virus blocks interferon effector function by inducing protein kinase R phosphorylation Academic Article
- Identification of amino acid residues critical for the anti-interferon activity of the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus Academic Article
- Identification of lps2 as a key transducer of myd88-independent tir signalling Academic Article
- Immunological and pathological consequences of coxsackievirus RNA persistence in the heart Academic Article
- In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance Academic Article
- In vivo conversion of bm plasmacytoid dc into cd11b(+) conventional dc during virus infection Academic Article
- Induction of systemic autoimmunity by a xenobiotic requires endosomal TLR trafficking and signaling from the late endosome and endolysosome but not type I IFN Academic Article
- Induction of type-i interferon genes and interferon-inducible genes in embryonal stem-cells devoid of interferon regulatory factor-i Academic Article
- Infected cd8 alpha(-) dendritic cells are the predominant source of il-10 during establishment of persistent viral infection Academic Article
- Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I Academic Article
- Inhibition of hepatitis B virus replication by interferon requires proteasome activity Academic Article
- Inhibition of lupus by genetic alteration of the interferon-alpha/beta receptor Academic Article
- Inhibition of the type I interferon response by the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus Academic Article
- Interferon-gamma is a major regulator of C1-inhibitor synthesis by human-blood monocytes Academic Article
- Is sequence conservation in interferons due to selection for functional proteins Academic Article
- Junin virus infection activates the type I interferon pathway in a RIG-I-dependent manner Academic Article
- Limited hepatitis B virus replication space in the chronically hepatitis C virus-infected liver Academic Article
- Lymphoblastoid B-cell lines produce an interleukin-1-like activity that can be serologically distinct from macrophage interleukin-1 Academic Article
- Lymphocytic choriomeningitis virus differentially affects the virus-induced type I interferon response and mitochondrial apoptosis mediated by RIG-I/MAVS Academic Article
- Male germ cells support long-term propagation of Zika virus Academic Article
- Mice devoid of interferon regulatory factor-1 (irf-1) show normal expression of type-i interferon genes Academic Article
- Mx protein - constitutive expression in 3t3-cells transformed with cloned mx cdna confers selective resistance to influenza-virus Academic Article
- Natural-killer cell-activity in patients with multiple-sclerosis given alpha-interferon Academic Article
- Not more than 117 base-pairs of 5'-flanking sequence are required for inducible expression of a human ifn-alpha gene Academic Article
- Organization of the murine mx gene and characterization of its interferon-inducible and virus-inducible promoter Academic Article
- Persistent LCMV infection is controlled by blockade of type I interferon signaling Academic Article
- Persistent virus infection inhibits type i interferon production by plasmacytoid dendritic cells to facilitate opportunistic infections Academic Article
- RIG-I enhanced interferon independent apoptosis upon Junin virus infection Academic Article
- Release of lymphokines after Epstein-Barr virus-infection in vitro. I. Sources of and kinetics of production of interferons and interleukins in normal humans Academic Article
- Release of lymphokines after infection with Epstein-Barr-virus in vitro .2. A monocyte-dependent inhibitor of interleukin-1 down-regulates the production of interleukin-2 and interferon-gamma in rheumatoid-arthritis Academic Article
- Requirements for "Fire and ICE" differ between animal models of autoimmunity: comment on the article by Kahlenberg et al Academic Article
- Reversible silencing of enhancers by sequences derived from the human ifn-alpha promoter Academic Article
- Secretion of interferon by bacillus-subtilis Academic Article
- Self-association of lymphocytic choriomeningitis virus nucleoprotein is mediated by its N-terminal region and is not required for its anti-interferon function Academic Article
- Single amino-acid changes that render human ifn-alpha-2 biologically-active on mouse cells Academic Article
- Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells Academic Article
- Structural relationship of human interferon-alpha genes and pseudogenes Academic Article
- Structure and expression of cloned murine ifn-alpha genes Academic Article
- Structure and expression of human ifn-alpha genes Academic Article
- Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus Academic Article
- Systemic alpha-interferon therapy of multiple-sclerosis Academic Article
- TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity Academic Article
- TLRs and interferons: a central paradigm in autoimmunity Academic Article
- The 5'-flanking region of a human IFN-alpha gene mediates viral induction of transcription Academic Article
- The C-terminal region of lymphocytic choriomeningitis virus nucleoprotein contains distinct and segregable functional domains involved in NP-Z interaction and counteraction of the type I interferon response Academic Article
- The alpha-interferons: some answers and many questions Academic Article
- The chromosomal location of mouse interferon alpha-genes Academic Article
- The expression of human interferon alpha-genes Academic Article
- The interferon genes Academic Article
- The tpl2 mutation sluggish impairs type i ifn production and increases susceptibility to group b streptococcal disease Academic Article
- The use of lymphocytic choriomeningitis virus reassortants to map viral genes causing virulence Academic Article
- Too much of a good thing: Sustained type 1 interferon signaling limits humoral responses to secondary viral infection Academic Article
- Transcriptional activation of the mouse mx gene by type-i interferon Academic Article
- Two non-allelic human interferon alpha genes with identical coding regions Academic Article
- Type I consensus IFN (IFN-con1) gene transfer into KSHV/HHV-8-infected BCBL-1 cells causes inhibition of viral lytic cycle activation via induction of apoptosis and abrogates tumorigenicity in sCID mice Academic Article
- Type I interferon is a therapeutic target for virus-induced lethal vascular damage Academic Article
- Type I interferon suppresses de novo virus-specific CD4 Th1 immunity during an established persistent viral infection Academic Article
- Type I interferons (α/β) in immunity and autoimmunity Academic Article
- Type i interferon during viral infections: Multiple triggers for a multifunctional mediator Academic Article
- Vesicular stomatitis virus glycoprotein g activates a specific antiviral toll-like receptor 4-dependent pathway Academic Article
- Viral persistence and chronic immunopathology in the adult central nervous system following coxsackievirus infection during the neonatal period Academic Article
- Viral rna induces type i interferon-dependent cytokine release and cell death in mesangial cells via melanoma-differentiation-associated gene-5 implications for viral infection-associated glomerulonephritis Academic Article
- Viruses evade the immune system through type i interferon-mediated stat2-dependent, but stat1-independent, signaling Academic Article