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• A 46-nucleotide promoter segment from an IFN-alpha gene renders an unrelated promoter inducible by virus  Academic Article
• A Jekyll and Hyde profile: Type 1 interferon signaling plays a prominent role in the initiation and maintenance of a persistent virus infection  Academic Article
• A novel, quantitative bioassay for type I interferon using a recombinant indicator cell line  Academic Article
• A recombinant human enzyme for enhanced interstitial transport of therapeutics  Academic Article
• Alpha and beta type 1 interferon signaling: passage for diverse biologic outcomes  Academic Article
• Altered tissue distribution of viral replication and t-cell spreading is pivotal in the protection against fatal lymphocytic choriomeningitis in mice after neutralization of ifn-alpha/beta  Academic Article
• An IRF-3-, IRF-5-, and IRF-7-independent pathway of dengue viral resistance utilizes IRF-1 to stimulate type I and II interferon responses  Academic Article
• Analysis of the MCMV resistome by ENU mutagenesis  Academic Article
• Arenavirus nucleoproteins prevent activation of nuclear factor kappa b  Academic Article
• Bone marrow plasmacytoid dendritic cells can differentiate into myeloid dendritic cells upon virus infection  Academic Article
• Cachectin tumor necrosis factor stimulates collagenase and prostaglandin-e2 production by human synovial-cells and dermal fibroblasts  Academic Article
• Cd14 is required for myd88-independent lps signaling  Academic Article
• Clinical-trial of natural alpha interferon in multiple-sclerosis  Academic Article
• Constitutive, long-term production of human interferons by hamster-cells containing multiple copies of a cloned interferon gene  Academic Article
• Cytotoxic T lymphocyte responsiveness after resolution of chronic hepatitis B virus infection  Academic Article
• D471G mutation in LCMV-NP affects its ability to self-associate and results in a dominant negative effect in viral RNA synthesis  Academic Article
• Deficient signaling in mice devoid of double-stranded rna-dependent protein kinase  Academic Article
• Different pathways mediate virus inducibility of the human ifn-alpha-1 and ifn-beta genes  Academic Article
• Differential expression of human interferon genes  Academic Article
• Differential inhibition of type I interferon induction by arenavirus nucleoproteins  Academic Article
• Effects of recombinant human interferons on rheumatoid-arthritis lymphocytes-B activated by Epstein-Barr-virus  Academic Article
• Efficient t cell activation via a toll-interleukin 1 receptor-independent pathway  Academic Article
• Enhanced antibacterial potential in UBP43-deficient mice against Salmonella typhimurium infection by up-regulation type IIFN signaling  Academic Article
• Epstein-Barr-virus complement C3d receptor is an interferon-alpha receptor  Academic Article
• Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus  Academic Article
• Formation of genes-coding for hybrid proteins by recombination between related, cloned genes in escherichia-coli  Academic Article
• Hepatitis C virus blocks interferon effector function by inducing protein kinase R phosphorylation  Academic Article
• Identification of amino acid residues critical for the anti-interferon activity of the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus  Academic Article
• Identification of lps2 as a key transducer of myd88-independent tir signalling  Academic Article
• Immunological and pathological consequences of coxsackievirus RNA persistence in the heart  Academic Article
• In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance  Academic Article
• In vivo conversion of bm plasmacytoid dc into cd11b(+) conventional dc during virus infection  Academic Article
• Induction of systemic autoimmunity by a xenobiotic requires endosomal TLR trafficking and signaling from the late endosome and endolysosome but not type I IFN  Academic Article
• Induction of type-i interferon genes and interferon-inducible genes in embryonal stem-cells devoid of interferon regulatory factor-i  Academic Article
• Infected cd8 alpha(-) dendritic cells are the predominant source of il-10 during establishment of persistent viral infection  Academic Article
• Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I  Academic Article
• Inhibition of hepatitis B virus replication by interferon requires proteasome activity  Academic Article
• Inhibition of lupus by genetic alteration of the interferon-alpha/beta receptor  Academic Article
• Inhibition of the type I interferon response by the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus  Academic Article
• Interferon-gamma is a major regulator of C1-inhibitor synthesis by human-blood monocytes  Academic Article
• Is sequence conservation in interferons due to selection for functional proteins  Academic Article
• Junin virus infection activates the type I interferon pathway in a RIG-I-dependent manner  Academic Article
• Limited hepatitis B virus replication space in the chronically hepatitis C virus-infected liver  Academic Article
• Lymphoblastoid B-cell lines produce an interleukin-1-like activity that can be serologically distinct from macrophage interleukin-1  Academic Article
• Lymphocytic choriomeningitis virus differentially affects the virus-induced type I interferon response and mitochondrial apoptosis mediated by RIG-I/MAVS  Academic Article
• Male germ cells support long-term propagation of Zika virus  Academic Article
• Mice devoid of interferon regulatory factor-1 (irf-1) show normal expression of type-i interferon genes  Academic Article
• Mx protein - constitutive expression in 3t3-cells transformed with cloned mx cdna confers selective resistance to influenza-virus  Academic Article
• Natural-killer cell-activity in patients with multiple-sclerosis given alpha-interferon  Academic Article
• Not more than 117 base-pairs of 5'-flanking sequence are required for inducible expression of a human ifn-alpha gene  Academic Article
• Organization of the murine mx gene and characterization of its interferon-inducible and virus-inducible promoter  Academic Article
• Persistent LCMV infection is controlled by blockade of type I interferon signaling  Academic Article
• Persistent virus infection inhibits type i interferon production by plasmacytoid dendritic cells to facilitate opportunistic infections  Academic Article
• RIG-I enhanced interferon independent apoptosis upon Junin virus infection  Academic Article
• Release of lymphokines after Epstein-Barr virus-infection in vitro. I. Sources of and kinetics of production of interferons and interleukins in normal humans  Academic Article
• Release of lymphokines after infection with Epstein-Barr-virus in vitro .2. A monocyte-dependent inhibitor of interleukin-1 down-regulates the production of interleukin-2 and interferon-gamma in rheumatoid-arthritis  Academic Article
• Requirements for "Fire and ICE" differ between animal models of autoimmunity: comment on the article by Kahlenberg et al  Academic Article
• Reversible silencing of enhancers by sequences derived from the human ifn-alpha promoter  Academic Article
• Secretion of interferon by bacillus-subtilis  Academic Article
• Self-association of lymphocytic choriomeningitis virus nucleoprotein is mediated by its N-terminal region and is not required for its anti-interferon function  Academic Article
• Single amino-acid changes that render human ifn-alpha-2 biologically-active on mouse cells  Academic Article
• Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells  Academic Article
• Structural relationship of human interferon-alpha genes and pseudogenes  Academic Article
• Structure and expression of cloned murine ifn-alpha genes  Academic Article
• Structure and expression of human ifn-alpha genes  Academic Article
• Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus  Academic Article
• Systemic alpha-interferon therapy of multiple-sclerosis  Academic Article
• TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity  Academic Article
• TLRs and interferons: a central paradigm in autoimmunity  Academic Article
• The 5'-flanking region of a human IFN-alpha gene mediates viral induction of transcription  Academic Article
• The C-terminal region of lymphocytic choriomeningitis virus nucleoprotein contains distinct and segregable functional domains involved in NP-Z interaction and counteraction of the type I interferon response  Academic Article
• The alpha-interferons: some answers and many questions  Academic Article
• The chromosomal location of mouse interferon alpha-genes  Academic Article
• The expression of human interferon alpha-genes  Academic Article
• The interferon genes  Academic Article
• The tpl2 mutation sluggish impairs type i ifn production and increases susceptibility to group b streptococcal disease  Academic Article
• The use of lymphocytic choriomeningitis virus reassortants to map viral genes causing virulence  Academic Article
• Too much of a good thing: Sustained type 1 interferon signaling limits humoral responses to secondary viral infection  Academic Article
• Transcriptional activation of the mouse mx gene by type-i interferon  Academic Article
• Two non-allelic human interferon alpha genes with identical coding regions  Academic Article
• Type I consensus IFN (IFN-con1) gene transfer into KSHV/HHV-8-infected BCBL-1 cells causes inhibition of viral lytic cycle activation via induction of apoptosis and abrogates tumorigenicity in sCID mice  Academic Article
• Type I interferon is a therapeutic target for virus-induced lethal vascular damage  Academic Article
• Type I interferon suppresses de novo virus-specific CD4 Th1 immunity during an established persistent viral infection  Academic Article
• Type I interferons (α/β) in immunity and autoimmunity  Academic Article
• Type i interferon during viral infections: Multiple triggers for a multifunctional mediator  Academic Article
• Vesicular stomatitis virus glycoprotein g activates a specific antiviral toll-like receptor 4-dependent pathway  Academic Article
• Viral persistence and chronic immunopathology in the adult central nervous system following coxsackievirus infection during the neonatal period  Academic Article
• Viral rna induces type i interferon-dependent cytokine release and cell death in mesangial cells via melanoma-differentiation-associated gene-5 implications for viral infection-associated glomerulonephritis  Academic Article
• Viruses evade the immune system through type i interferon-mediated stat2-dependent, but stat1-independent, signaling  Academic Article