subject area of
- Association between nocturnal vagal tone and sleep depth, sleep quality, and fatigue in alcohol dependence Academic Article
- Discovery of 5''-chloro-N-[(5,6-dimethoxypyridin-2-yl)methyl]-2,2':5',3''-terpyridine-3'-carboxamide (MK-1064): a selective orexin 2 receptor antagonist (2-SORA) for the treatment of insomnia Academic Article
- Discovery of MK-3697: a selective orexin 2 receptor antagonist (2-SORA) for the treatment of insomnia Academic Article
- Discovery of diazepane amide DORAs and 2-SORAs enabled by exploration of isosteric quinazoline replacements Academic Article
- Discovery of dual orexin receptor antagonists (DORAs) for the treatment of insomnia Academic Article
- Discovery of dual orexin receptor antagonists with rat sleep efficacy enabled by expansion of the acetonitrile-assisted/diphosgene-mediated 2,4-dichloropyrimidine synthesis Academic Article
- Discovery of the dual orexin receptor antagonist [(7R)-4-(5-chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone (MK-4305) for the treatment of insomnia Academic Article
- EEG spectral analysis in primary insomnia: NREM period effects and sex differences Academic Article
- Gabapentin for the treatment of alcohol use disorder Academic Article
- Measuring sleep disturbances in patients with alcohol use disorders: a short questionnaire suitable for routine practice Academic Article
- Orexin receptor antagonists: medicinal chemistry and therapeutic potential Academic Article
- Orexin receptor antagonists: new therapeutic agents for the treatment of insomnia Academic Article
- Ritanserin in the treatment of alcohol dependence: a multi-center clinical trial Academic Article
- SLEEPLESS-ness and insomnia in fruit flies Academic Article
- The dual orexin receptor antagonist, DORA-22, lowers histamine levels in the lateral hypothalamus and prefrontal cortex without lowering hippocampal acetylcholine Academic Article
- The neurobiology, clinical efficacy and safety of acamprosate in the treatment of alcohol dependence Academic Article