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Hyperalgesia

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  • A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition  Academic Article
  • Activation of the liver x receptor increases neuroactive steroid levels and protects from diabetes-induced peripheral neuropathy  Academic Article
  • Autotaxin, a synthetic enzyme of lysophosphatidic acid (LPA), mediates the induction of nerve-injured neuropathic pain  Academic Article
  • Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain  Academic Article
  • Chromenones as potent bradykinin B1 antagonists  Academic Article
  • Chronic CRF1 receptor blockade reduces heroin intake escalation and dependence-induced hyperalgesia  Academic Article
  • Combined inhibition of FAAH and COX produces enhanced anti-allodynic effects in mouse neuropathic and inflammatory pain models  Academic Article
  • Development of mechanical hypersensitivity in rats during heroin and ethanol dependence: Alleviation by crf1 receptor antagonism  Academic Article
  • Differential modulation of inflammatory pain by a selective estrogen receptor beta agonist  Academic Article
  • Discovery, optimization, and biological evaluation of 5-(2-(trifluoromethyl)phenyl)indazoles as a novel class of transient receptor potential A1 (TRPA1) antagonists  Academic Article
  • Evaluation of NHS carbamates as a potent and selective class of endocannabinoid hydrolase inhibitors  Academic Article
  • Extended access to nicotine leads to a CRF1 receptor dependent increase in anxiety-like behavior and hyperalgesia in rats  Academic Article
  • Fatty acid amide hydrolase blockade attenuates the development of collagen-induced arthritis and related thermal hyperalgesia in mice  Academic Article
  • Full fatty acid amide hydrolase inhibition combined with partial monoacylglycerol lipase inhibition: augmented and sustained antinociceptive effects with reduced cannabimimetic side effects in mice  Academic Article
  • Ghrelin prevents cisplatin-induced mechanical hyperalgesia and cachexia  Academic Article
  • Increased hyperalgesia after tissue injury and faster recovery of allodynia after nerve injury in the GalR1 knockout mice  Academic Article
  • Inflammatory signals enhance piezo2-mediated mechanosensitive currents  Academic Article
  • Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling  Academic Article
  • Intrathecal galanin alleviates allodynia-like behaviour in rats after partial peripheral nerve injury  Academic Article
  • Investigation of diacylglycerol lipase alpha inhibition in the mouse lipopolysaccharide inflammatory pain model  Academic Article
  • Lysophosphatidic acid-3 receptor-mediated feed-forward production of lysophosphatidic acid: An initiator of nerve injury-induced neuropathic pain  Academic Article
  • Lysophosphatidylcholine induces neuropathic pain through an action of autotaxin to generate lysophosphatidic acid  Academic Article
  • Mechanisms of antinociception of spinal galanin: How does galanin inhibit spinal sensitization?  Academic Article
  • N-pyridin-3-yl- and N-quinolin-3-yl-benzamides: Modulators of human vanilloid receptor 1 (TRPV1)  Academic Article
  • Nociceptin (1-7) antagonizes nociceptin-induced hyperalgesia in mice  Academic Article
  • Nociceptive responses in interleukin-6-deficient mice to peripheral inflammation and peripheral nerve section  Academic Article
  • Opioids, pain, the brain, and hyperkatifeia: a framework for the rational use of opioids for pain  Academic Article
  • Orally efficacious NR2B-selective NMDA receptor antagonists  Academic Article
  • Rational design of fatty acid amide hydrolase inhibitors that act by covalently bonding to two active site residues  Academic Article
  • Regulation of inflammatory pain by inhibition of fatty acid amide hydrolase  Academic Article
  • Role of peripheral hyperpolarization-activated cyclic nucleotide-modulated channel pacemaker channels in acute and chronic pain models in the rat  Academic Article
  • Systemic galnon, a low-molecular weight galanin receptor agonist, reduces heat hyperalgesia in rats with nerve injury  Academic Article
  • TRPA1 contributes to cold hypersensitivity  Academic Article
  • The fatty acid amide hydrolase (FAAH) inhibitor PF-3845 acts in the nervous system to reverse LPS-induced tactile allodynia in mice  Academic Article
  • The monoacylglycerol lipase inhibitor JZL184 suppresses inflammatory pain in the mouse carrageenan model  Academic Article
  • The selective monoacylglycerol lipase inhibitor MJN110 produces opioid-sparing effects in a mouse neuropathic pain model  Academic Article

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