subject area of

• A family of starch-active polysaccharide monooxygenases  Academic Article
• A fully active catalytic domain of bovine aspartyl (asparaginyl) beta-hydroxylase expressed in Escherichia-coli: characterization and evidence for the identification of an active-site region in vertebrate alpha-ketoglutarate-dependent dioxygenases  Academic Article
• A hypervariable region of P450IIC5 confers progesterone 21-hydroxylase activity to P450IIC1  Academic Article
• CYP2C19 participates in tolbutamide hydroxylation by human liver microsomes  Academic Article
• Cassette mutagenesis of a potential substrate recognition region of cytochrome P450 2C2  Academic Article
• Cellobiose dehydrogenase and a copper-dependent polysaccharide monooxygenase potentiate cellulose degradation by neurospora crassa  Academic Article
• Cellulose degradation by polysaccharide monooxygenases  Academic Article
• Characterization of a cDNA-encoding a human kidney, cytochrome-P-450 4A fatty-acid omega-hydroxylase and the cognate enzyme expressed in Escherichia-coli  Academic Article
• Characterization of a rabbit gene encoding a clofibrate-inducible fatty-acid omega-hydroxylase - CYP4A6  Academic Article
• Clinical analysis of NSCLC patients reveals lack of association between EGFR mutation and TET1 downregulation  Academic Article
• Cloning and expression of 3 rabbit kidney cDNAs encoding lauric acid omega-hydroxylases  Academic Article
• Combinatorial generation of complexity by redox enzymes in the chaetoglobosin A biosynthesis  Academic Article
• Crystallization and preliminary x-ray analysis of tetracenomycin a2 oxygenase: A flavoprotein hydroxylase involved in polyketide biosynthesis  Academic Article
• Determinants of regioselective hydroxylation in the fungal polysaccharide monooxygenases  Academic Article
• Diazepam metabolism by cDNA-Expressed human 2C p450s: identification of P4502C18 and P4502C19 as low K(M) diazepam N-demethylases  Academic Article
• Differential effects of mutations in substrate recognition site 1 of cytochrome P450 2C2 on lauric acid and progesterone hydroxylation  Academic Article
• Differential induction by "2,3,7,8-tetrachlorodibenzo-p-dioxin of multiple forms of rabbit microsomal cytochrome-P-450 - evidence for tissue-specificity  Academic Article
• Differential regulation of human CYP4A genes by peroxisome proliferators and dexamethasone  Academic Article
• Effects of transition metals on nitric oxide synthase catalysis  Academic Article
• Expression of rabbit cytochromes-p4504a which catalyze the omega-hydroxylation of arachidonic-acid, fatty-acids, and prostaglandins  Academic Article
• FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor  Academic Article
• Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement  Academic Article
• Fluorescent mechanism-based probe for aerobic flavin-dependent enzyme activity  Academic Article
• Heteroaryl urea inhibitors of fatty acid amide hydrolase: Structure-mutagenicity relationships for arylamine metabolites  Academic Article
• Horseradish peroxidase catalyzed hydroxylations: Mechanistic studies  Academic Article
• Human abh3 structure and key residues for oxidative demethylation to reverse DNA/rna damage  Academic Article
• Hypoxic culture induces expression of sialin, a sialic acid transporter, and cancer-associated gangliosides containing non-human sialic acid on human cancer cells  Academic Article
• Identification of amino acid substitutions that confer a high affinity for sulfaphenazole binding and a high catalytic efficiency for warfarin metabolism to P450 2C19  Academic Article
• Identification of human CYP2C19 residues that confer S-mephenytoin 4'-hydroxylation activity to CYP2C9  Academic Article
• Induction of specific cytochrome P450s involved in aflatoxin B1 metabolism in hepatitis B virus transgenic mice  Academic Article
• Interaction of the peroxisome proliferator-activated receptor-alpha with the retinoid-X receptor-alpha unmasks a cryptic peroxisome proliferator response element that overlaps an ARP-1-binding site in the CYP4A6 promoter  Academic Article
• Major antigen of liver kidney microsomal autoantibodies in idiopathic autoimmune hepatitis is cytochrome P450db1  Academic Article
• Metal ligand substitution and evidence for quinone formation in taurine/alpha-ketoglutarate dioxygenase  Academic Article
• Microsomal cytochrome P450 2C5: comparison to microbial P450s and unique features  Academic Article
• N-acylglycine amidation: implications for the biosynthesis of fatty acid primary amides  Academic Article
• Neuropeptide converting enzyme-activities in csf of low-back-pain patients  Academic Article
• Novel sequence determinants in peroxisome proliferator signaling  Academic Article
• Oxidative cleavage of cellulose by fungal copper-dependent polysaccharide monooxygenases  Academic Article
• Purification of major cytochrome-P-450 of liver-microsomes from rabbits treated with "2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)  Academic Article
• Quantitative nature of Arabidopsis responses during compatible and incompatible interactions with the bacterial pathogen Pseudomonas syringae  Academic Article
• Rabbit pregnane X receptor is activated by rifampicin  Academic Article
• Rabbit prostaglandin omega-hydroxylase (CYP4A4) - gene structure and expression  Academic Article
• Regulation of p450 4a expression by peroxisome proliferator activated receptors  Academic Article
• Reinvigorating the Chiral Pool: Chemoenzymatic Approaches to Complex Peptides and Terpenoids  Academic Article
• Role of the peroxisome proliferator-activated receptor in cytochrome P450 4A gene regulation  Academic Article
• Signal mimics derived from a metagenomic analysis of the gypsy moth gut microbiota  Academic Article
• Squalene-2,3-oxide, an intermediate in the enzymatic conversion of squalene to lanosterol and cholesterol  Academic Article
• Structural basis for substrate targeting and catalysis by fungal polysaccharide monooxygenases  Academic Article
• Structural basis of autoregulation of phenylalanine hydroxylase  Academic Article
• Structural diversity of human xenobiotic-metabolizing cytochrome P450 monooxygenases  Academic Article
• Structural insight into the altered substrate specificity of human cytochrome P450 2A6 mutants  Academic Article
• Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway  Academic Article
• Structure-function of cytochromes P450 and flavin-containing monooxygenases: implications for drug metabolism  Academic Article
• Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen  Academic Article
• Sulfaphenazole derivatives as tools for comparing cytochrome P450 2C5 and human cytochromes P450 2Cs: identification of a new high affinity substrate common to those enzymes  Academic Article
• Synthetic inhibitors of cytochrome p-450 2a6: Inhibitory activity, difference spectra, mechanism of inhibition, and protein cocrystallization  Academic Article
• Targeted antipeptide antibodies to cytochrome P450 2C18 based on epitope mapping of an inhibitory monoclonal antibody to P450 2C51  Academic Article
• The CYP4A isoforms hydroxylate epoxyeicosatrienoic acids to form high affinity peroxisome proliferator-activated receptor ligands  Academic Article
• The catalytic site of cytochrome P4504A11 (CYP4A11) and its L131F mutant  Academic Article
• The peroxisome proliferator-activated receptor mediates the induction of CYP4A6, a cytochrome-P450 fatty-acid omega-hydroxylase, by clofibric acid  Academic Article
• The peroxisome proliferator-activated receptor: transcriptional activation of the CYP4A6 gene  Academic Article
• The structural basis for substrate anchoring, active site selectivity, and product formation by P450 PikC from Streptomyces venezuelae  Academic Article
• Xenobiotic metabolism and mutation in a human lymphoblastoid cell line  Academic Article
• hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function  Academic Article