subject area of
- A family of starch-active polysaccharide monooxygenases Academic Article
- A fully active catalytic domain of bovine aspartyl (asparaginyl) beta-hydroxylase expressed in Escherichia-coli: characterization and evidence for the identification of an active-site region in vertebrate alpha-ketoglutarate-dependent dioxygenases Academic Article
- A hypervariable region of P450IIC5 confers progesterone 21-hydroxylase activity to P450IIC1 Academic Article
- CYP2C19 participates in tolbutamide hydroxylation by human liver microsomes Academic Article
- Cassette mutagenesis of a potential substrate recognition region of cytochrome P450 2C2 Academic Article
- Cellobiose dehydrogenase and a copper-dependent polysaccharide monooxygenase potentiate cellulose degradation by neurospora crassa Academic Article
- Cellulose degradation by polysaccharide monooxygenases Academic Article
- Characterization of a cDNA-encoding a human kidney, cytochrome-P-450 4A fatty-acid omega-hydroxylase and the cognate enzyme expressed in Escherichia-coli Academic Article
- Characterization of a rabbit gene encoding a clofibrate-inducible fatty-acid omega-hydroxylase - CYP4A6 Academic Article
- Clinical analysis of NSCLC patients reveals lack of association between EGFR mutation and TET1 downregulation Academic Article
- Cloning and expression of 3 rabbit kidney cDNAs encoding lauric acid omega-hydroxylases Academic Article
- Combinatorial generation of complexity by redox enzymes in the chaetoglobosin A biosynthesis Academic Article
- Crystallization and preliminary x-ray analysis of tetracenomycin a2 oxygenase: A flavoprotein hydroxylase involved in polyketide biosynthesis Academic Article
- Determinants of regioselective hydroxylation in the fungal polysaccharide monooxygenases Academic Article
- Diazepam metabolism by cDNA-Expressed human 2C p450s: identification of P4502C18 and P4502C19 as low K(M) diazepam N-demethylases Academic Article
- Differential effects of mutations in substrate recognition site 1 of cytochrome P450 2C2 on lauric acid and progesterone hydroxylation Academic Article
- Differential induction by "2,3,7,8-tetrachlorodibenzo-p-dioxin of multiple forms of rabbit microsomal cytochrome-P-450 - evidence for tissue-specificity Academic Article
- Differential regulation of human CYP4A genes by peroxisome proliferators and dexamethasone Academic Article
- Effects of transition metals on nitric oxide synthase catalysis Academic Article
- Expression of rabbit cytochromes-p4504a which catalyze the omega-hydroxylation of arachidonic-acid, fatty-acids, and prostaglandins Academic Article
- FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor Academic Article
- Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement Academic Article
- Fluorescent mechanism-based probe for aerobic flavin-dependent enzyme activity Academic Article
- Heteroaryl urea inhibitors of fatty acid amide hydrolase: Structure-mutagenicity relationships for arylamine metabolites Academic Article
- Horseradish peroxidase catalyzed hydroxylations: Mechanistic studies Academic Article
- Human abh3 structure and key residues for oxidative demethylation to reverse DNA/rna damage Academic Article
- Hypoxic culture induces expression of sialin, a sialic acid transporter, and cancer-associated gangliosides containing non-human sialic acid on human cancer cells Academic Article
- Identification of amino acid substitutions that confer a high affinity for sulfaphenazole binding and a high catalytic efficiency for warfarin metabolism to P450 2C19 Academic Article
- Identification of human CYP2C19 residues that confer S-mephenytoin 4'-hydroxylation activity to CYP2C9 Academic Article
- Induction of specific cytochrome P450s involved in aflatoxin B1 metabolism in hepatitis B virus transgenic mice Academic Article
- Interaction of the peroxisome proliferator-activated receptor-alpha with the retinoid-X receptor-alpha unmasks a cryptic peroxisome proliferator response element that overlaps an ARP-1-binding site in the CYP4A6 promoter Academic Article
- Major antigen of liver kidney microsomal autoantibodies in idiopathic autoimmune hepatitis is cytochrome P450db1 Academic Article
- Metal ligand substitution and evidence for quinone formation in taurine/alpha-ketoglutarate dioxygenase Academic Article
- Microsomal cytochrome P450 2C5: comparison to microbial P450s and unique features Academic Article
- N-acylglycine amidation: implications for the biosynthesis of fatty acid primary amides Academic Article
- Neuropeptide converting enzyme-activities in csf of low-back-pain patients Academic Article
- Novel sequence determinants in peroxisome proliferator signaling Academic Article
- Oxidative cleavage of cellulose by fungal copper-dependent polysaccharide monooxygenases Academic Article
- Purification of major cytochrome-P-450 of liver-microsomes from rabbits treated with "2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) Academic Article
- Quantitative nature of Arabidopsis responses during compatible and incompatible interactions with the bacterial pathogen Pseudomonas syringae Academic Article
- Rabbit pregnane X receptor is activated by rifampicin Academic Article
- Rabbit prostaglandin omega-hydroxylase (CYP4A4) - gene structure and expression Academic Article
- Regulation of p450 4a expression by peroxisome proliferator activated receptors Academic Article
- Reinvigorating the Chiral Pool: Chemoenzymatic Approaches to Complex Peptides and Terpenoids Academic Article
- Role of the peroxisome proliferator-activated receptor in cytochrome P450 4A gene regulation Academic Article
- Signal mimics derived from a metagenomic analysis of the gypsy moth gut microbiota Academic Article
- Squalene-2,3-oxide, an intermediate in the enzymatic conversion of squalene to lanosterol and cholesterol Academic Article
- Structural basis for substrate targeting and catalysis by fungal polysaccharide monooxygenases Academic Article
- Structural basis of autoregulation of phenylalanine hydroxylase Academic Article
- Structural diversity of human xenobiotic-metabolizing cytochrome P450 monooxygenases Academic Article
- Structural insight into the altered substrate specificity of human cytochrome P450 2A6 mutants Academic Article
- Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway Academic Article
- Structure-function of cytochromes P450 and flavin-containing monooxygenases: implications for drug metabolism Academic Article
- Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen Academic Article
- Sulfaphenazole derivatives as tools for comparing cytochrome P450 2C5 and human cytochromes P450 2Cs: identification of a new high affinity substrate common to those enzymes Academic Article
- Synthetic inhibitors of cytochrome p-450 2a6: Inhibitory activity, difference spectra, mechanism of inhibition, and protein cocrystallization Academic Article
- Targeted antipeptide antibodies to cytochrome P450 2C18 based on epitope mapping of an inhibitory monoclonal antibody to P450 2C51 Academic Article
- The CYP4A isoforms hydroxylate epoxyeicosatrienoic acids to form high affinity peroxisome proliferator-activated receptor ligands Academic Article
- The catalytic site of cytochrome P4504A11 (CYP4A11) and its L131F mutant Academic Article
- The peroxisome proliferator-activated receptor mediates the induction of CYP4A6, a cytochrome-P450 fatty-acid omega-hydroxylase, by clofibric acid Academic Article
- The peroxisome proliferator-activated receptor: transcriptional activation of the CYP4A6 gene Academic Article
- The structural basis for substrate anchoring, active site selectivity, and product formation by P450 PikC from Streptomyces venezuelae Academic Article
- Xenobiotic metabolism and mutation in a human lymphoblastoid cell line Academic Article
- hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function Academic Article