subject area of

• "Don't know much bile-ology"  Academic Article
• "Resistance" to PSC-RANTES revisited: two mutations in human immunodeficiency virus type 1 HIV-1 SF162 or simian-human immunodeficiency virus SHIV SF162-p3 do not confer resistance  Academic Article
• "Viral deja vu" elicits organ-specific immune disease independent of reactivity to self  Academic Article
• 'Late onset' ornithine transcarbamylase deficiency: function of three purified recombinant mutant enzymes  Academic Article
• 'Muscle-sparing' statins: preclinical profiles and future clinical use  Academic Article
• 'Reverse' alpha-ketoamide-based p38 map kinase inhibitors  Academic Article
• 'SNO'-storms compromise protein activity and mitochondrial metabolism in neurodegenerative disorders  Academic Article
• 'Translocatory proteins' and 'protein transduction domains': A critical analysis of their biological effects and the underlying mechanisms  Academic Article
• (18)F Fluoroazabenzoxazoles as potential amyloid plaque PET tracers: synthesis and in vivo evaluation in rhesus monkey  Academic Article
• (18)F-labeled isoindol-1-one and isoindol-1,3-dione derivatives as potential PET imaging agents for detection of beta-amyloid fibrils  Academic Article
• (4,2)D projection-reconstruction experiments for protein backbone assignment: application to human carbonic anhydrase II and calbindin D(28K)  Academic Article
• -Amino acid substitution of peptide-mediated NF-κB suppression in mdx mice preserves therapeutic benefit in skeletal muscle, but causes kidney toxicity  Academic Article
• 1,3,8-Triazaspiro[4.5]decane-2,4-diones as efficacious pan-inhibitors of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) for the treatment of anemia  Academic Article
• 1-(2-(2,2,2-Trifluoroethoxy)ethyl-1H-pyrazolo 4,3-d pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors  Academic Article
• 1-(2-Ethoxyethyl)-1H-pyrazolo 4,3-d pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors  Academic Article
• 1-H NMR detection of small molecules in human urine with a deep cavitand synthetic receptor  Academic Article
• 1-deamino-8-D-arginine vasopressin and cryoprecipitate in variant von Willebrand disease  Academic Article
• 1-deamino-8-D-arginine vasopressin: a new pharmacological approach to the management of haemophilia and von Willebrands' diseases  Academic Article
• 1-year survival in a randomized trial of facilitated reperfusion results from the finesse (facilitated intervention with enhanced reperfusion speed to stop events) trial  Academic Article
• 10-(2-benzoxazolcarbonyl)-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid: a potential inhibitor of GAR transformylase and AICAR transformylase  Academic Article
• 10-formyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid (10-formyl-DDACTHF): a potent cytotoxic agent acting by selective inhibition of human GAR Tfase and the de novo purine biosynthetic pathway  Academic Article
• 10-formyl-5,8,10-trideazafolic acid (10-formyl-TDAF): a potent inhibitor of glycinamide ribonucleotide transformylase  Academic Article
• 100 cemented versus 100 noncemented stems with comparison of 25 matched pairs  Academic Article
• 13C NMR studies of the product complex of glyoxalase I  Academic Article
• 14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination  Academic Article
• 14-3-3 proteins in neuronal development and function  Academic Article
• 1H, 13C and 15N chemical shift assignments for the human Pitx2 homeodomain and a R24H homeodomain mutant  Academic Article
• 2 cases of agammaglobulinemia detected by determining the blood group [Article in Russian]  Academic Article
• 2-(3,5-dimethylphenyl)tryptamine derivatives that bind to the GnRH receptor  Academic Article
• 2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: Design and synthesis of a potent and isoform selective PKC-zeta inhibitor  Academic Article
• 2-(Pyrrolidin-1-yl)ethyl-3,4-dihydroisoquinolin-1(2H)-one Derivatives as Potent and Selective Histamine-3 Receptor Antagonists  Academic Article
• 2-Amino- 1,2,4 triazolo 1,5-a pyridines as JAK2 inhibitors  Academic Article
• 2-Amino-4-bis(aryloxybenzyl)aminobutanoic acids: A novel scaffold for inhibition of ASCT2-mediated glutamine transport  Academic Article
• 2-Aminobenzimidazoles as potent Aurora kinase inhibitors  Academic Article
• 2-Arylbenzoxazoles as novel cholesteryl ester transfer protein inhibitors: optimization via array synthesis  Academic Article
• 2-Bromopalmitate analogues as activity-based probes to explore palmitoyl acyltransferases  Academic Article
• 2-Chlorodeoxyadenosine activity in patients with untreated, indolent non-Hodgkin's lymphoma  Academic Article
• 2-Propylthiouracil does not replace glutathione for the glutathione transferases  Academic Article
• 2-chlorodeoxyadenosine in the treatment of chronic refractory immune thrombocytopenic purpura  Academic Article
• 2-microglobulin: a free immunoglobulin domain  Academic Article
• 2-year outcome after angiographically documented myocardial reperfusion for acute coronary-occlusion  Academic Article
• 2010 white paper on recent issues in regulated bioanalysis & global harmonization of bioanalytical guidance  Academic Article
• 24 hours in the life of HIV-1 in a T cell line  Academic Article
• 28th Bethesda Conference. Task force 5: Assessment, approval, and regulation of new technology  Academic Article
• 384 hanging drop arrays give excellent Z-factors and allow versatile formation of co-culture spheroids  Academic Article
• 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)pi perazine-1-carbothioamide (ML267), a Potent Inhibitor of Bacterial Phosphopantetheinyl Transferase That Attenuates Secondary Metabolism and Thwarts Bacterial Growth  Academic Article
• 4-Aminoindazolyl-dihydrofuro 3,4-d pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase  Academic Article
• 4-Aminopyridyl-based CYP51 inhibitors as anti-Trypanosoma cruzi drug leads with improved pharmacokinetic profile and in vivo potency  Academic Article
• 4-Methyl-6,7-dihydro-4H-triazolo 4,5-c pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidate  Academic Article
• 4-O-acetyl-N-acetylneuraminic acid in the N-linked carbohydrate structures of equine and guinea pig alpha 2-macroglobulins, potent inhibitors of influenza virus infection  Academic Article
• 4E10-resistant HIV-1 isolated from four subjects with rare membrane-proximal external region polymorphisms  Academic Article
• 5 alpha-Androstan-3 alpha,17 beta-diol is a hormone: stimulation of cAMP accumulation in human and dog prostate  Academic Article
• 5-HT(2C) agonists as therapeutics for the treatment of schizophrenia  Academic Article
• 5-ht(1a) receptor binding is increased after recovery from bulimia nervosa compared to control women and is associated with behavioral inhibition in both groups  Academic Article
• 5-lipoxygenase-activating protein inhibitors: development of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM103)  Academic Article
• 50 Years of structural immunology  Academic Article
• 68Ga-PSMA-11 PET imaging of response to androgen receptor inhibition: first human experience  Academic Article
• 7-Hydroxynaphthalen-1-yl-urea and -amide antagonists of human vanilloid receptor 1  Academic Article
• 7-alkylidenecephalosporin esters as inhibitors of human leukocyte elastase  Academic Article
• 8-Hydroxyquinoline and hydroxamic acid inhibitors of botulinum neurotoxin BoNT/A  Academic Article
• 8-Tetrahydropyran-2-yl chromans: highly selective beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors  Academic Article
• 9p21 DNA variants associated with coronary artery disease impair interferon-gamma signalling response  Academic Article
• A "flip-flop" rotation stage for routine dual-axis electron cryotomography  Academic Article
• A 15-ketosterol is a liver X receptor ligand that suppresses sterol-responsive element binding protein-2 activity  Academic Article
• A 193-amino acid fragment of the SARS coronavirus S protein efficiently binds angiotensin-converting enzyme 2  Academic Article
• A 3-dimensional extracellular matrix as a delivery system for the transplantation of glioma-targeting neural stem/progenitor cells  Academic Article
• A 46-nucleotide promoter segment from an IFN-alpha gene renders an unrelated promoter inducible by virus  Academic Article
• A 50-kDa membrane protein mediates sialic acid-independent binding and infection of conjunctival cells by adenovirus type 37  Academic Article
• A 52-kD protein is a novel component of the SS-A/Ro antigenic particle  Academic Article
• A 9-nt segment of a cellular mRNA can function as an internal ribosome entry site (IRES) and when present in linked multiple copies greatly enhances IRES activity  Academic Article
• A Bellagio consensus. Children's Vaccine Initiative Ad Hoc Committe on an investment strategy for measles control  Academic Article
• A Bifluorescent-Based Assay for the Identification of Neutralizing Antibodies against SARS-CoV-2 Variants of Concern In Vitro and In Vivo  Academic Article
• A Bifunctional NAD(+) for Profiling Poly-ADP-Ribosylation-Dependent Interacting Proteins  Academic Article
• A CAT reporter construct allows ultrasensitive estimation of TNF synthesis, and suggests that the TNF gene has been silenced in non-macrophage cell lines  Academic Article
• A Child With Wegener's Granulomatosis and Severe Hemophilia A: Interplay of Disease Processes  Academic Article
• A Clinical Indications Prediction Scale Based on TWIST1 for Human Mesenchymal Stem Cells  Academic Article
• A Comprehensive Explanation Framework for Biomedical Time Series Classification  Academic Article
• A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response  Academic Article
• A DNA vaccine for ebola virus is safe and immunogenic in a phase i clinical trial  Academic Article
• A Fc engineering approach to define functional humoral correlates of immunity against Ebola virus  Academic Article
• A Functional Screen for Regulators of CKDN2A Reveals MEOX2 as a Transcriptional Activator of INK4a  Academic Article
• A GTP affinity probe for proteomics highlights flexibility in purine nucleotide selectivity  Academic Article
• A Good Night's Sleep After the ICU Does Better Sleep Lead to Better Recovery After Critical Illness?  Academic Article
• A HaloTag-based multicolor fluorogenic sensor visualizes and quantifies proteome stress in live cells using solvatochromic and molecular rotor-based fluorophores  Academic Article
• A Herpesvirus Protein Selectively Inhibits Cellular mRNA Nuclear Export  Academic Article
• A JAK/STAT-mediated inflammatory signaling cascade drives oncogenesis in AF10-rearranged AML  Academic Article
• A LC-MS-based workflow for measurement of branched fatty acid esters of hydroxy fatty acids  Academic Article
• A Naive-Like Population of Human CD1d-Restricted T Cells Expressing Intermediate Levels of Promyelocytic Leukemia Zinc Finger  Academic Article
• A New World primate deficient in tetherin-mediated restriction of human immunodeficiency virus type 1  Academic Article
• A Novel Recombinant Influenza Virus Neuraminidase Vaccine Candidate Stabilized by a Measles Virus Phosphoprotein Tetramerization Domain Provides Robust Protection from Virus Challenge in the Mouse Model  Academic Article
• A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis  Academic Article
• A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate  Academic Article
• A Plasmodium gene family encoding Maurer's cleft membrane proteins: structural properties and expression profiling  Academic Article
• A Rapid Assay for SARS-CoV-2 Neutralizing Antibodies That Is Insensitive to Antiretroviral Drugs  Academic Article
• A SNAP-tag fluorogenic probe mimicking the chromophore of the red fluorescent protein Kaede  Academic Article
• A Short Hairpin RNA Screen of Interferon-Stimulated Genes Identifies a Novel Negative Regulator of the Cellular Antiviral Response  Academic Article
• A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice  Academic Article
• A Single Protein S-acyl Transferase Acts through Diverse Substrates to Determine Cryptococcal Morphology, Stress Tolerance, and Pathogenic Outcome  Academic Article
• A Small Molecule Exploits Hidden Structural Features within the RNA Repeat Expansion That Causes c9ALS/FTD and Rescues Pathological Hallmarks  Academic Article
• A THEMIS:SHP1 complex promotes T-cell survival  Academic Article
• A TRP channel that senses cold stimuli and menthol  Academic Article
• A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model  Academic Article
• A Useful Combination of Quantitative Ultrashort Echo Time MR Imaging and a Probing Device for Biomechanical Evaluation of Articular Cartilage  Academic Article
• A Yersinia-pseudotuberculosis protein which cross-reacts with HLA-B27  Academic Article
• A bifunctional molecule that displays context-dependent cellular activity  Academic Article
• A binary plasmid system for shuffling combinatorial antibody libraries  Academic Article
• A biochemically distinct sub-population of neurons in the human substantia gelatinosa. Study with G-6-PD histochemistry  Academic Article
• A bioinformatic assay for pluripotency in human cells  Academic Article
• A biomechanical evaluation of three surgical techniques for subscapularis repair  Academic Article
• A biomechanical study of the aponeurotic inguinal hernia repair  Academic Article
• A biosynthetic approach for the incorporation of unnatural amino acids into proteins  Academic Article
• A biparatopic HER2-targeting antibody-drug conjugate induces tumor regression in primary models refractory to or ineligible for HER2-targeted therapy  Academic Article
• A bleeding disorder due to deficiency of alpha-2-antiplasmin  Academic Article
• A blood based 12-miRNA signature of Alzheimer disease patients  Academic Article
• A blueprint for HIV vaccine discovery  Academic Article
• A brave new MYC-amplified world  Academic Article
• A brief review of the past and future of platelet P2Y12 antagonist  Academic Article
• A broadly neutralizing human monoclonal antibody exhibits in vivo efficacy against both human metapneumovirus and respiratory syncytial virus  Academic Article
• A c-alpha model for the transmembrane alpha helices of gap junction intercellular channels  Academic Article
• A call for action on primary care and public health integration  Academic Article
• A camera-phone based study reveals erratic eating pattern and disrupted daily eating-fasting cycle among adults in India  Academic Article
• A candidate circuit approach to investigating autism  Academic Article
• A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase  Academic Article
• A candidate live inactivatable attenuated vaccine for aids  Academic Article
• A carbohydrate-conjugated deep cavitand permits observation of caviplexes in human serum  Academic Article
• A carbohydrate-derived splice modulator  Academic Article
• A case of an entrapped rotational atherectomy burr  Academic Article
• A case study on forensic polymer analysis by dios-ms: The suspect who gave us the slip (r)  Academic Article
• A catechol-O-methyltransferase that is essential for auditory function in mice and humans  Academic Article
• A cd4+ cytotoxic lymphocyte-t clone to a conserved epitope on human-immunodeficiency-virus type-1 p24 - cytotoxic activity and secretion of interleukin-2 and interleukin-6  Academic Article
• A cdc6 protein-binding peptide selected using a bacterial two-hybrid-like system is a cell cycle inhibitor  Academic Article
• A cell-based luciferase assay amenable to high-throughput screening of inhibitors of arenavirus budding  Academic Article
• A cell-cycle nuclear autoantigen containing WD-40 motifs expressed mainly in S and G2 phase cells  Academic Article
• A cell-cycle-regulated inhibitor of cyclin-dependent kinases  Academic Article
• A cell-free expression and purification process for rapid production of protein biologics  Academic Article
• A cell-penetrating peptide from a novel pVII-pIX phage-displayed random peptide library  Academic Article
• A cell-penetrating peptidic GRP78 ligand for tumor cell-specific prodrug therapy  Academic Article
• A cell-permeable synthetic transcription factor mimic  Academic Article
• A cellular gene encodes scrapie prp 27-30 protein  Academic Article
• A central strategy for converting natural products into fluorescent probes  Academic Article
• A change in the conformation of prions accompanies the emergence of a new prion strain  Academic Article
• A chaperone trap contributes to the onset of cystic fibrosis  Academic Article
• A chemical approach for detecting sulfenic acid-modified proteins in living cells  Academic Article
• A chemical approach for identifying O-GlcNAc-modified proteins in cells  Academic Article
• A chemical approach for the detection of protein sulfinylation  Academic Article
• A chemical approach to stem cell biology  Academic Article
• A chemical approach to stem-cell biology and regenerative medicine  Academic Article
• A chemical biology approach reveals period shortening of the mammalian circadian clock by specific inhibition of GSK-3β  Academic Article
• A chemical chaperone decouples TDP-43 disordered domain phase separation from fibrillation  Academic Article
• A chemical genomic analysis of decoquinate, a plasmodium falciparum cytochrome b inhibitor  Academic Article
• A chemical platform for improved induction of human iPSCs  Academic Article
• A chemical switch for inhibitor-sensitive alleles of any protein kinase  Academic Article
• A chemical switch regulates fibrate specificity for peroxisome proliferator-activated receptor alpha (ppar alpha) versus liver x receptor  Academic Article
• A chemical, genetic, and structural analysis of the nuclear bile acid receptor fxr  Academic Article
• A chemically functionalized magnetic nanoplatform for rapid and specific biomolecular recognition and separation  Academic Article
• A chemically induced vaccine strategy for prostate cancer  Academic Article
• A chemically programmed antibody is a long-lasting and potent inhibitor of influenza neuraminidase  Academic Article
• A chemically stable fluorescent marker of the ureter  Academic Article
• A chemo-enzymatic approach to the study of carbohydrate recognition in biological systems  Academic Article
• A chemoproteomic platform to quantitatively map targets of lipid-derived electrophiles  Academic Article
• A child with fever after hematopoietic stem cell transplantation  Academic Article
• A chimeric hiv-1 envelope glycoprotein trimer with an embedded granulocyte-macrophage colony-stimulating factor (gm-csf) domain induces enhanced antibody and t cell responses  Academic Article
• A chloroacetamidine-based inactivator of protein arginine methyltransferase 1: Design, synthesis, and in vitro and in vivo evaluation  Academic Article
• A chromatin binding-site in the tail domain of nuclear lamins that interacts with core histones  Academic Article
• A circulating, disease-specific, mechanism-linked biomarker for ATTR polyneuropathy diagnosis and response to therapy prediction  Academic Article
• A clinical study of an unusual case of asthma associated with urticaria pigmentosa  Academic Article
• A clinical trial comparing primary coronary angioplasty with tissue plasminogen activator for acute myocardial infarction  Academic Article
• A coactivator trap identifies NONO (p54(nrb)) as a component of the cAMP-signaling pathway  Academic Article
• A code for RanGDP binding in ankyrin repeats defines a nuclear import pathway  Academic Article
• A colorectal cancer classification system that associates cellular phenotype and responses to therapy  Academic Article
• A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection  Academic Article
• A combination of docking/dynamics simulations and pharmacophoric modeling to discover new dual c-Src/Abl kinase inhibitors  Academic Article
• A combination of low-dose cyclophosphamide and colony-stimulating factors is more cost-effective than granulocyte-colony-stimulating factors alone in mobilizing peripheral blood stem and progenitor cells  Academic Article
• A combinatorial approach to characterize the substrate specificity of protein arginine methyltransferase 1  Academic Article
• A combined EM and proteomic analysis places HIV-1 Vpu at the crossroads of retromer and ESCRT complexes: PTPN23 is a Vpu-cofactor  Academic Article
• A combined chemical and genetic approach for the generation of induced pluripotent stem cells  Academic Article
• A combined proteomics/genomics approach links hepatitis C virus infection with nonsense-mediated mRNA decay  Academic Article
• A common MECP2 haplotype associates with reduced cortical surface area in humans in two independent populations  Academic Article
• A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to Legionnaires' disease  Academic Article
• A common genetic polymorphism (46 C to T substitution) in the 5 '-untranslated region of the coagulation factor XII gene is associated with low translation efficiency and decrease in plasma factor XII level  Academic Article
• A common pharmacophore for epothilone and taxanes: Molecular basis for drug resistance conferred by tubulin mutations in human cancer cells  Academic Article
• A common promoter variant of the leptin gene is associated with changes in the relationship between serum leptin and fat mass in obese girls  Academic Article
• A common solution to group 2 influenza virus neutralization  Academic Article
• A comparative analysis of HGSC and Celera human genome assemblies and gene sets  Academic Article
• A comparative encyclopedia of DNA elements in the mouse genome  Academic Article
• A comparative immunogenicity study of hiv-1 virus-like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble monomeric gp120  Academic Article
• A comparison between activated protein C and des-1-41-light chain-activated protein C in reactions with type 1 plasminogen activator inhibitor  Academic Article
• A comparison of cf and non-cf school-age children undergoing lung transplantation  Academic Article
• A comparison of debulking versus dilatation of bifurcation coronary arterial narrowings (from the caveat i trial)  Academic Article
• A comparison of directional atherectomy with coronary angioplasty in patients with coronary-artery disease  Academic Article
• A comparison of ionic versus nonionic contrast medium during primary percutaneous transluminal coronary angioplasty for acute myocardial infarction (gusto iib)  Academic Article
• A comparison of linear and cyclic peptoid oligomers as potent antimicrobial agents  Academic Article
• A comparison of noninternalizing (herkinorin) and internalizing (DAMGO) mu-opioid agonists on cellular markers related to opioid tolerance and dependence  Academic Article
• A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes  Academic Article
• A comparison of reteplase with alteplase for acute myocardial infarction  Academic Article
• A comparison of selected quantitative trait loci associated with alcohol use phenotypes in humans and mouse models  Academic Article
• A comparison of the Celera and Ensembl predicted gene sets reveals little overlap in novel genes  Academic Article
• A comparison of the abilities of plasma kallikrein, beta-Factor XIIa, Factor XIa and urokinase to activate plasminogen  Academic Article
• A comparison of the atomic model of F-actin with cryo-electron micrographs of actin and decorated actin  Academic Article
• A comparison of the enzymatic and physicochemical properties of human glutathione transferase M4-4 and three other human Mu class enzymes  Academic Article
• A comparison of two neurologic scoring instruments for multiple sclerosis  Academic Article
• A compass for stem-cell differentiation  Academic Article
• A competition assay to identify amyloidogenesis inhibitors by monitoring the fluorescence emitted by the covalent attachment of a stilbene derivative to transthyretin  Academic Article
• A complex equilibrium among partially unfolded conformations in monomeric transthyretin  Academic Article
• A complex of Protocadherin-19 and N-cadherin mediates a novel mechanism of cell adhesion  Academic Article
• A complexin/synaptotagmin 1 switch controls fast synaptic vesicle exocytosis  Academic Article
• A complexity measure for selective matching of signals by the brain  Academic Article
• A comprehensive approach to zinc-finger recombinase customization enables genomic targeting in human cells  Academic Article
• A computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein induces apoptosis in infected cells  Academic Article
• A concise and flexible synthesis of the potent anti-influenza agents tamiflu and tamiphosphor  Academic Article
• A conformational switch in human immunodeficiency virus gp41 revealed by the structures of overlapping epitopes recognized by neutralizing antibodies  Academic Article
• A consensus-hemagglutinin-based DNA vaccine that protects mice against divergent H5N1 influenza viruses  Academic Article
• A conserved "hydrophobic staple motif" plays a crucial role in the refolding of human glutathione transferase P1-1  Academic Article
• A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis  Academic Article
• A conserved family of prolyl-4-hydroxylases that modify HIF  Academic Article
• A conserved hiv gp120 glycoprotein structure involved in chemokine receptor binding  Academic Article
• A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase  Academic Article
• A conserved motif in the itk ph-domain is required for phosphoinositide binding and tcr signaling but dispensable for adaptor protein interactions  Academic Article
• A conserved proliferating cell nuclear antigen-interacting protein sequence in Chk1 is required for checkpoint function  Academic Article
• A conserved protein interaction interface on the type 5 G protein beta subunit controls proteolytic stability and activity of R7 family regulator of G protein signaling proteins  Academic Article
• A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension  Academic Article
• A contemporary assessment of low-molecular-weight heparin for the treatment of acute coronary syndromes: Factoring in new trials and meta-analysis data  Academic Article
• A continuous, spectroscopic analysis of the kinetics of elastase secretion by neutrophils. The dependence of secretion upon receptor occupancy  Academic Article
• A cost-effective fluorescence mini-microscope for biomedical applications  Academic Article
• A credit-card library approach for disrupting protein-protein interactions  Academic Article
• A critical analysis of codon optimization in human therapeutics  Academic Article
• A critical evaluation of enzyme immunoassay kits for detection of antinuclear autoantibodies of defined specificities. II. Potential for quantitation of antibody content  Academic Article
• A critical evaluation of enzyme immunoassay kits for detection of antinuclear autoantibodies of defined specificities. III. Comparative performance characteristics of academic and manufacturers' laboratories  Academic Article
• A critical evaluation of enzyme immunoassays for detection of antinuclear autoantibodies of defined specificities. I. Precision, sensitivity, and specificity  Academic Article
• A critical role for Pin2/TRF1 in ATM-dependent regulation. Inhibition of Pin2/TRF1 function complements telomere shortening, radiosensitivity, and the G(2)/M checkpoint defect of ataxia-telangiectasia cells  Academic Article
• A critical role for TORC1 in cellular senescence  Academic Article
• A critical role for monocytes and cd14 in endotoxin-induced endothelial-cell activation  Academic Article
• A critical role for the sphingosine analog aal-r in dampening the cytokine response during influenza virus infection  Academic Article
• A critical role of the C-terminal segment for allosteric inhibitor-induced aberrant multimerization of HIV-1 integrase  Academic Article
• A cross-neutralizing antibody between HIV-1 and influenza virus  Academic Article
• A cross-over inhibitor of the botulinum neurotoxin light chain B: A natural product implicating an exosite mechanism of action  Academic Article
• A cross-species analysis in pancreatic neuroendocrine tumors reveals molecular subtypes with distinctive clinical, metastatic, developmental, and metabolic characteristics  Academic Article
• A cross-species analysis of a mouse model of breast cancer-specific osteolysis and human bone metastases using gene expression profiling  Academic Article
• A crucial role of mitochondrial Hsp40 in preventing dilated cardiomyopathy  Academic Article
• A crystal structure of a model of the repeating r(CGG) transcript found in fragile X syndrome  Academic Article
• A curcumin derivative that inhibits vinyl carbamate-induced lung carcinogenesis via activation of the Nrf2 protective response  Academic Article
• A customized self-assembling peptide hydrogel for dental pulp tissue engineering  Academic Article
• A cyclin-dependent kinase inhibitor inducing cancer cell differentiation: biochemical identification using Xenopus egg extracts  Academic Article
• A decrease in the size of the basal ganglia following prenatal alcohol exposure - a preliminary-report  Academic Article
• A defective V-kappa A2 allele in navajos which play play a role in increased susceptibility to haemophilus influenzae type disease  Academic Article
• A demonstration of the intrinsic importance of stabilizing hydrophobic binding and noncovalent van der Waals contacts dominant in the noncovalent CC-1065/b-DNA binding  Academic Article
• A designed peptidomimetic agonistic ligand of trka nerve growth factor receptors  Academic Article
• A di-acidic (DxE) code directs concentration of cargo during export from the endoplasmic reticulum  Academic Article
• A diffuse infiltrative CD8 lymphocytosis syndrome in human immunodeficiency virus (HIV) infection: a host immune response associated with HLA-DR5  Academic Article
• A direct comparison of tirofiban and abciximab during percutaneous coronary revascularization and stent placement: rationale and design of the TARGET study  Academic Article
• A direct enzymatic assay for the esterolytic activity of activated hageman factor  Academic Article
• A direct, plasmin-independent assay for plasminogen activator  Academic Article
• A discovery strategy for selective inhibitors of c-Src in complex with the focal adhesion kinase SH3/SH2-binding region  Academic Article
• A disease-specific measure of health-related quality of life for use in adults with immune thrombocytopenic purpura: Its development and validation  Academic Article
• A disease-specific measure of health-related quality of life in adults with chronic immune thrombocytopenic purpura: Psychometric testing in an open-label clinical trial  Academic Article
• A distinct reactive oxygen species profile confers chemoresistance in glioma-propagating cells and associates with patient survival outcome  Academic Article
• A distinct slow cellular pathway involving soluble mediators for the t-cell-instructed induction of monocyte tissue factor activity in an allogeneic immune-response  Academic Article
• A dominant-negative peroxisome proliferator-activated receptor gamma (ppar gamma) mutant is a constitutive repressor and inhibits ppar gamma-mediated adipogenesis  Academic Article
• A double monoclonal IgG1k and IgG2k in a single myeloma patient - variation in clonal products and therapeutic responses  Academic Article
• A double-blind, placebo-controlled pilot study to evaluate the efficacy and safety of oral nalmefene HCl for alcohol dependence  Academic Article
• A double-blind, placebo-controlled study of oral nalmefene for alcohol dependence  Academic Article
• A double-blind, placebo-controlled trial of desipramine for primary alcohol dependence stratified on the presence or absence of major depression  Academic Article
• A double-blind, placebo-controlled, randomized trial of cladribine in relapsing-remitting multiple sclerosis  Academic Article
• A double-mimetic peptide efficiently neutralizes HIV-1 by bridging the CD4- and coreceptor-binding sites of gp120  Academic Article
• A double-stranded rna-activated protein kinase-dependent pathway mediating stress-induced apoptosis  Academic Article
• A double-variant transthyretin allele (Ser-6, Ile-33) in the israeli patient SKO with familial amyloidotic polyneuropathy  Academic Article
• A downstream kinase of the mammalian target of rapamycin, p70s6k1, regulates human double minute 2 protein phosphorylation and stability  Academic Article
• A drosophila g(1)-specific cyclin e homolog exhibits different modes of expression during embryogenesis  Academic Article
• A dual array-based approach to assess the abundance and posttranslational modification state of signaling proteins  Academic Article
• A dual color immunohistochemistry assay for measurement of cereblon in multiple myeloma patient samples  Academic Article
• A dynamic model of HIV integrase inhibition and drug resistance  Academic Article
• A dynamic search process underlies microRNA targeting  Academic Article
• A dynamin mutant defines a superconstricted prefission state  Academic Article
• A dystroglycan mutation associated with limb-girdle muscular dystrophy  Academic Article
• A facile system for encoding unnatural amino acids in mammalian cells  Academic Article
• A factor IX-deficient mouse model for hemophilia B gene therapy  Academic Article
• A family of cyclin homologs that control the g1 phase in yeast  Academic Article
• A family of leukemia inhibitory factor-binding peptides that can act as antagonists when conjugated to poly(ethylene glycol)  Academic Article
• A family of lipopolysaccharide binding-proteins involved in responses to gram-negative sepsis  Academic Article
• A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange  Academic Article
• A feasibility study showing [68Ga]citrate PET detects prostate cancer  Academic Article
• A fibroblast growth factor binding protein in human cerebral spinal fluid  Academic Article
• A five-amino-acid motif in the undefined region of the tlr8 ectodomain is required for species-specific ligand recognition  Academic Article
• A fluopol-ABPP HTS assay to identify PAD inhibitors  Academic Article
• A fluorescence-based thiol quantification assay for ultra-high-throughput screening for inhibitors of coenzyme a production  Academic Article
• A fluorescent plate reader assay for ceramide kinase  Academic Article
• A fluorogenic aryl fluorosulfate for intraorganellar transthyretin imaging in living cells and in Caenorhabditis elegans  Academic Article
• A fluorometric assay for red-blood-cell antibodies  Academic Article
• A focused microarray approach to functional glycomics: Transcriptional regulation of the glycome  Academic Article
• A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function  Academic Article
• A fragment of human TrpRS as a potent antagonist of ocular angiogenesis  Academic Article
• A fully active catalytic domain of bovine aspartyl (asparaginyl) beta-hydroxylase expressed in Escherichia-coli: characterization and evidence for the identification of an active-site region in vertebrate alpha-ketoglutarate-dependent dioxygenases  Academic Article
• A functional genomics approach to the mode of action of apratoxin A  Academic Article
• A functional genomics strategy reveals Rora as a component of the mammalian circadian clock  Academic Article
• A functional interaction between RIP140 and PGC-1 alpha regulates the expression of the lipid droplet protein CIDEA  Academic Article
• A gdp-bound form of rab1 inhibits protein export from the endoplasmic-reticulum and transport between golgi compartments  Academic Article
• A gender-specific blood-based gene expression score for assessing obstructive coronary artery disease in nondiabetic patients: Results of the personalized risk evaluation and diagnosis in the coronary tree (predict) trial  Academic Article
• A gene atlas of the mouse and human protein-encoding transcriptomes  Academic Article
• A gene encoding an intestinal-enriched member of the Kruppel-like factor family expressed in intestinal epithelial cells  Academic Article
• A gene expression phenotype in lymphocytes from Friedreich ataxia patients  Academic Article
• A gene expression profile of alzheimer's disease  Academic Article
• A gene expression profile of embryonic stem cells and embryonic stem cell-derived neurons  Academic Article
• A gene for hirschsprung disease (megacolon) in the pericentromeric region of human chromosome-10  Academic Article
• A gene-specific role for the Ssu72 RNAPII CTD phosphatase in HIV-1 Tat transactivation  Academic Article
• A general approach for receptor and antibody-targeted detection of native proteins utilizing split-luciferase reassembly  Academic Article
• A general approach to site-specific antibody drug conjugates  Academic Article
• A general fragment-based approach to identify and optimize bioactive ligands targeting RNA  Academic Article
• A general method for insertion of functional proteins within proteins via combinatorial selection of permissive junctions  Academic Article
• A general method to quantify quasi-equivalence in icosahedral viruses  Academic Article
• A general system for evaluating the efficiency of chromophore-assisted light inactivation (CALI) of proteins reveals Ru(ii) tris-bipyridyl as an unusually efficient "warhead"  Academic Article
• A genetic analysis of pax3-fkhr, the oncogene of alveolar rhabdomyosarcoma  Academic Article
• A genetic determinant of the striatal dopamine response to alcohol in men  Academic Article
• A genetic network that suppresses genome rearrangements in Saccharomyces cerevisiae and contains defects in cancers  Academic Article
• A genetically encoded aza-Michael acceptor for covalent cross-linking of protein-receptor complexes  Academic Article
• A genetically encoded fluorescent amino acid  Academic Article
• A genetically encoded fluorescent probe in mammalian cells  Academic Article
• A genetically encoded multifunctional TRAIL trimer facilitates cell-specific targeting and tumor cell killing  Academic Article
• A genetically encoded photocaged amino acid  Academic Article
• A genetically humanized mouse model for hepatitis C virus infection  Academic Article
• A genome sequencing program for novel undiagnosed diseases  Academic Article
• A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control  Academic Article
• A genome-wide RNAi screen for modifiers of the circadian clock in human cells  Academic Article
• A genome-wide association study of anorexia nervosa  Academic Article
• A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A  Academic Article
• A genome-wide association study on common snps and rare cnvs in anorexia nervosa  Academic Article
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• A genome-wide scan for loci linked to forearm bone mineral density  Academic Article
• A genome-wide search for chromosomal loci linked to mental health wellness in relatives at high risk for bipolar affective disorder among the old order amish  Academic Article
• A genome-wide search for schizophrenia susceptibility genes  Academic Article
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• A genomewide scan of male sexual orientation  Academic Article
• A genomic screen identifies TYRO3 as a MITF regulator in melanoma  Academic Article
• A genomic-systems biology map for cardiovascular function  Academic Article
• A geographic cline of skull and brain morphology among individuals of european ancestry  Academic Article
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• A global assessment of stem cell engineering  Academic Article
• A global map of lipid-binding proteins and their ligandability in cells  Academic Article
• A global metabolite profiling approach to identify protein-metabolite interactions  Academic Article
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• A glycoengineered enzyme with multiple mannose-6-phosphates is internalized into diseased cells to restore its activity in lysosomes  Academic Article
• A golden-age for adhesion  Academic Article
• A gp41 MPER-specific llama VHH requires a hydrophobic CDR3 for neutralization but not for antigen recognition  Academic Article
• A growing family of receptor genes for lysophosphatidic acid (LPA) and other lysophospholipids (LPs)  Academic Article
• A gtpase distinct from ran is involved in nuclear protein import  Academic Article
• A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival  Academic Article
• A haplotype map of the human genome  Academic Article
• A heat-sensitive TRP channel expressed in keratinocytes  Academic Article
• A helical processing pipeline for EM structure determination of membrane proteins  Academic Article
• A helix replacement mechanism directs metavinculin functions  Academic Article
• A helper-independent adenovirus vector with e1, e3, and fiber deleted: Structure and infectivity of fiberless particles  Academic Article
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• A high-throughput assay for assessing the cell permeability of combinatorial libraries  Academic Article
• A high-throughput assay for siRNA-based circadian screens in human U2OS cells  Academic Article
• A high-throughput assay for the identification of drugs against late-stage Plasmodium falciparum gametocytes  Academic Article
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• A higher degree of difficulty  Academic Article
• A highly acidic tyrosine 9 and a normally titrating tyrosine 212 contribute to the catalytic mechanism of human glutathione transferase A4-4  Academic Article
• A highly conserved arginine in gp120 governs HIV-1 binding to both syndecans and CCR5 via sulfated motifs  Academic Article
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• A homogeneous, high-throughput assay for phosphatidylinositol 5-phosphate 4-kinase with a novel, rapid substrate preparation  Academic Article
• A homozygous transthyretin variant associated with senile systemic amyloidosis - evidence for a late-onset disease of genetic etiology  Academic Article
• A hot new channel  Academic Article
• A human MAP kinase interactome  Academic Article
• A human aminoacyl-tRNA synthetase as a regulator of angiogenesis  Academic Article
• A human antibody to the CD4 binding site of gp120 capable of highly potent but sporadic cross clade neutralization of primary HIV-1  Academic Article
• A human antibody-drug conjugate targeting EphA2 inhibits tumor growth in vivo  Academic Article
• A human germ line antibody light chain with hydrolytic properties associated with multimerization status  Academic Article
• A human inferred germline antibody binds to an immunodominant epitope and neutralizes Zika virus  Academic Article
• A human microprotein that interacts with the mRNA decapping complex  Academic Article
• A human mitochondrial transcriptional activator can functionally replace a yeast mitochondrial HMG-box protein both in vivo and in vitro  Academic Article
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• A human short open reading frame (sORF)-encoded polypeptide that stimulates DNA end joining  Academic Article
• A human single-chain antibody specific for integrin alpha(3)beta(1) capable of cell internalization and delivery of antitumor agents  Academic Article
• A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol  Academic Article
• A human-brain glycoprotein related to the mouse-cell adhesion molecule l1  Academic Article
• A human-embryonic lung fibroblast with a high-density of muscarinic acetylcholine-receptors  Academic Article
• A human-infecting H10N8 influenza virus retains a strong preference for avian-type receptors  Academic Article
• A humanized aldolase antibody for selective chemotherapy and adaptor immunotherapy  Academic Article
• A humanized anti-4-1bb monoclonal antibody suppresses antigen-induced humoral immune response in nonhuman primates  Academic Article
• A humanized murine monoclonal antibody protects mice either before or after challenge with virulent Venezuelan equine encephalomyelitis virus  Academic Article
• A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters  Academic Article
• A hypothesis about the endogenous analogue of general anesthesia  Academic Article
• A journey through the exocytic pathway  Academic Article
• A juvenile hemochromatosis patient homozygous for a novel deletion of cdna nucleotide 81 of hemojuvelin  Academic Article
• A key role for corticotropin-releasing factor in alcohol dependence  Academic Article
• A labeled guanidine ligand for studying sweet taste  Academic Article
• A large noncoding rna is a marker for murine hepatocellular carcinomas and a spectrum of human carcinomas  Academic Article
• A lentiviral vector allowing physiologically regulated membrane-anchored and secreted antibody expression depending on B-cell maturation status  Academic Article
• A less costly regimen of alglucerase to treat gauchers-disease  Academic Article
• A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS  Academic Article
• A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals  Academic Article
• A linear amino acid sequence involved in the interaction of t-PA with its endothelial cell receptor  Academic Article
• A linkage between the hemostatic and immune systems embodied in the fibrinolytic release of lymphocyte suppressive peptides  Academic Article
• A lipid binding domain in sphingosine kinase 2  Academic Article
• A live-virus ''suicide'' vaccine for human immunodeficiency virus  Academic Article
• A liver-selective LXR inverse agonist that suppresses hepatic steatosis  Academic Article
• A low-molecular-weight entry inhibitor of both CCR5- and CXCR4-tropic strains of human immunodeficiency virus type 1 targets a novel site on gp41  Academic Article
• A major CYP2D6 autoepitope in autoimmune hepatitis type 2 and chronic hepatitis C is a three-dimensional structure homologous to other cytochrome P450 autoantigens  Academic Article
• A major histocompatibility complex-peptide-restricted antibody and t cell receptor molecules recognize their target by distinct binding modes - crystal structure of human leukocyte antigen (hla)-a1-mage-a1 in complex with fab-hyb3  Academic Article
• A maltose-binding protein fusion construct yields a robust crystallography platform for MCL1  Academic Article
• A mammalian expression system for high throughput antibody screening  Academic Article
• A mass spectrometry plate reader: monitoring enzyme activity and inhibition with a desorption/ionization on silicon (DIOS) platform  Academic Article
• A matter of life and death? The heart protection study and protection of clinical trial participants  Academic Article
• A measure for brain complexity - relating functional segregation and integration in the nervous-system  Academic Article
• A mechanism for neutrophil-mediated lysis of human neuroblastoma-cells  Academic Article
• A mechanism for tcr sharing between t cell subsets and individuals revealed by pyrosequencing  Academic Article
• A mechanistically novel, first oral therapy for multiple sclerosis: the development of fingolimod (FTY720, Gilenya)  Academic Article
• A metabolic labeling approach toward proteomic analysis of mucin-type O-linked glycosylation  Academic Article
• A metalloantibody that irreversibly binds a protein antigen  Academic Article
• A metallopeptide assembly of the HIV-1 gp41 coiled coil is an ideal receptor in fluorescence detection of ligand binding  Academic Article
• A metastasis map of human cancer cell lines  Academic Article
• A methionine-rich domain mediates CRM1-dependent nuclear export activity of Borna disease virus phosphoprotein  Academic Article
• A method based on the use of methanol as a stabilizing agent to prepare metal-free glyoxalase I and to reconstitute activity by addition of bivalent metal ions  Academic Article
• A method for identification of hiv gp140 binding memory b cells in human blood  Academic Article
• A method for localizing the early products of nonenzymatic glycosylation in fixed tissue  Academic Article
• A method for the generation of combinatorial antibody libraries using pIX phage display  Academic Article
• A methylation-mediator complex in hormone signaling  Academic Article
• A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targeting  Academic Article
• A missense mutation in human fatty acid amide hydrolase associated with problem drug use  Academic Article
• A missense mutation in the neutrophil cytochrome-b heavy-chain in cytochrome-positive x-linked chronic granulomatous-disease  Academic Article
• A missense mutation of the endothelin-b receptor gene in multigenic hirschsprungs-disease  Academic Article
• A mitochondrial targeting two-channel responsive fluorescence probe for imaging the superoxide radical anion in vitro and in vivo  Academic Article
• A model of measles virus-induced immunosuppression: Enhanced susceptibility of neonatal human pbls  Academic Article
• A modified alpha-galactosyl ceramide for staining and stimulating natural killer T cells  Academic Article
• A modular system for the assay of transcription regulatory signals - the sequence taatgarat is required for herpes-simplex virus immediate early gene activation  Academic Article
• A molecular approach to the classification of von Willebrand disease  Academic Article
• A molecular history of the amyloidoses  Academic Article
• A molecular model of RGD ligands. Antibody D gene segments that direct specificity for the integrin alpha IIb beta 3  Academic Article
• A molecular scheme for improved characterization of human embryonic stem cell lines  Academic Article
• A molecular switch regulating transcriptional repression and activation of PPARγ  Academic Article
• A monoclonal antibody that does not recognize tissue-type plasminogen activator bound to its naturally occurring inhibitor  Academic Article
• A monoclonal antibody to ADAM17 inhibits tumor growth by inhibiting EGFR and non-EGFR-Mediated Pathways  Academic Article
• A monoclonal-antibody reacting with distinct adhesion molecules defines a transition in the functional-state of the receptor cd11b/cd18 (mac-1)  Academic Article
• A monoclonal-antibody recognizes an o-acylated sialic-acid in a human melanoma-associated ganglioside  Academic Article
• A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration  Academic Article
• A multiaxial force-sensing implantable tibial prosthesis  Academic Article
• A multicenter, randomized trial of coronary angioplasty versus directional atherectomy for patients with saphenous vein bypass graft lesions  Academic Article
• A multicenter, randomized, controlled trial comparing Surfaxin (Lucinactant) lavage with standard care for treatment of meconium aspiration syndrome  Academic Article
• A multicenter, randomized, placebo-controlled trial of a new form of intravenous recombinant tissue-type plasminogen-activator (activase) in acute myocardial-infarction  Academic Article
• A multidisciplinary intervention to prevent the readmission of elderly patients with congestive-heart-failure  Academic Article
• A multifunctional bispecific antibody protects against Pseudomonas aeruginosa  Academic Article
• A multiplexed single-cell CRISPR screening platform enables systematic dissection of the unfolded protein response  Academic Article
• A multiscale statistical mechanical framework integrates biophysical and genomic data to assemble cancer networks  Academic Article
• A multivalent approach towards linked dual-pharmacology prostaglandin F receptor agonist/carbonic anhydrase-II inhibitors for the treatment of glaucoma  Academic Article
• A multivalent minigene vaccine, containing b-cell, cytotoxic t-lymphocyte, and t-h epitopes from several microbes, induces appropriate responses in vivo and confers protection against more than one pathogen  Academic Article
• A multivalent vaccination strategy for the prevention of old world arenavirus infection in humans  Academic Article
• A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response  Academic Article
• A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function  Academic Article
• A mutation in TGFB3 associated with a syndrome of low muscle mass, growth retardation, distal arthrogryposis and clinical features overlapping with Marfan and Loeys-Dietz syndrome  Academic Article
• A mutation in the human cyclin-dependent kinase interacting protein, ckshs2, interferes with cyclin-dependent kinase binding and biological function, but preserves protein structure and assembly  Academic Article
• A myristoylated pseudosubstrate peptide of PKC-ζ induces degranulation in HMC-1 cells independently of PKC-ζ activity  Academic Article
• A nanostructure-initiator mass spectrometry-based enzyme activity assay  Academic Article
• A nanostructured synthetic collagen mimic for hemostasis  Academic Article
• A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene  Academic Article
• A natural product ligand of the oxysterol receptor, liver x receptor  Academic Article
• A near-IR uncaging strategy based on cyanine photochemistry  Academic Article
• A negative feedback loop mediated by the Bcl6-cullin 3 complex limits Tfh cell differentiation  Academic Article
• A neural cell-adhesion molecule from human-brain  Academic Article
• A neurologic rating-scale (nrs) for use in multiple-sclerosis  Academic Article
• A new approach for evaluating antigen-specific t cell responses to myelin antigens during the course of multiple sclerosis  Academic Article
• A new congenital platelet abnormality characterized by spontaneous platelet aggregation, enhanced von Willebrand factor platelet interaction, and the presence of all von Willebrand factor multimers in plasma  Academic Article
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• A new gamma-interferon-inducible promoter and splice variants of an anti-angiogenic human tRNA synthetase  Academic Article
• A new lease on life for an HIV-neutralizing antibody class and vaccine target  Academic Article
• A new mechanism of allostery in a G protein-coupled receptor dimer  Academic Article
• A new model for binding of kinesin 13 to curved microtubule protofilaments  Academic Article
• A new model of macrophage stimulation by bacterial lipopolysaccharide  Academic Article
• A new perspective on V3 phenotype prediction  Academic Article
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• A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis  Academic Article
• A new regulatory switch in a JAK protein kinase  Academic Article
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• A new strategy for glycoprotein synthesis: ligation of synthetic glycopeptides with truncated proteins expressed in E. coli as TEV protease cleavable fusion protein  Academic Article
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• A next-generation cleaved, soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies  Academic Article
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• A non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis  Academic Article
• A non-thrombocytopenic bleeding disorder due to an igg4-kappa anti-gpiib/iiia autoantibody  Academic Article
• A noncanonical Frizzled2 pathway regulates epithelial-mesenchymal transition and metastasis  Academic Article
• A nonfucosylated variant of the anti-hiv-1 monoclonal antibody b12 has enhanced fc gamma riiia-mediated antiviral activity in vitro but does not improve protection against mucosal shiv challenge in macaques  Academic Article
• A nonproteolytic function of the 19s regulatory subunit of the 26s proteasome is required for efficient activated transcription by human rna polymerase ii  Academic Article
• A nonself sugar mimic of the hiv glycan shield shows enhanced antigenicity  Academic Article
• A notable case report of May-Hegglin anomaly with immune complex-related nephropathy: a genetic and histological analysis  Academic Article
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• A note on the genome scan meta-analysis statistic  Academic Article
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• A novel GJA8 mutation (p.V44A) causing autosomal dominant congenital cataract  Academic Article
• A novel HLA class II molecule (DR alpha-DQ beta) created by mismatched isotype pairing  Academic Article
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• A novel class of achiral seco-analogs of CC-1065 and the duocarmycins: design, synthesis, DNA binding, and anticancer properties  Academic Article
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• A novel gene encoding an integral membrane protein is mutated in nephropathic cystinosis  Academic Article
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• A novel human antibody against human immunodeficiency virus type 1 gp120 is v1, v2, and v3 loop dependent and helps delimit the epitope of the broadly neutralizing antibody immunoglobulin g1 b12  Academic Article
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• A novel method for generating region-specific monoclonal-antibodies to modified proteins - application to the identification of human glucosylated low-density lipoproteins  Academic Article
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• A novel mode of intervention with serine protease activity: targeting zymogen activation  Academic Article
• A novel molecular diagnostic marker for familial and early-onset coronary artery disease and myocardial infarction in the LRP8 gene  Academic Article
• A novel monoclonal antibody, L1A3, is directed to the functional site of the αv integrin subunit  Academic Article
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• A novel neuroprotective agent with antioxidant and nitric oxide synthase inhibitory action  Academic Article
• A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease  Academic Article
• A novel population of natural-killer progenitor cells isolated from human umbilical-cord blood  Academic Article
• A novel processive mechanism for DNA synthesis revealed by structure, modeling and mutagenesis of the accessory subunit of human mitochondrial DNA polymerase  Academic Article
• A novel quasi-species of glutathione transferase with high activity towards naturally occurring isothiocyanates evolves from promiscuous low-activity variants  Academic Article
• A novel role for protein arginine deiminase 4 in pluripotency: the emerging role of citrullinated histone H1 in cellular programming  Academic Article
• A novel role of farnesylation in targeting a mitotic checkpoint protein, human Spindly, to kinetochores  Academic Article
• A novel series of glucagon receptor antagonists with reduced molecular weight and lipophilicity  Academic Article
• A novel splice acceptor site mutation which produces multiple splicing abnormalities resulting in protein S deficiency type I  Academic Article
• A novel strategy for efficient production of anti-V3 human scFvs against HIV-1 clade C  Academic Article
• A novel transgenic mouse model for immunological evaluation of carcinoembryonic antigen-based DNA minigene vaccines  Academic Article
• A novel α2/α4 subtype-selective positive allosteric modulator of nicotinic acetylcholine receptors acting from the C-tail of an α subunit  Academic Article
• A novel, nonanaphylactogenic, bispecific IgE-CD3 antibody eliminates IgE1(+) B cells  Academic Article
• A novel, quantitative bioassay for type I interferon using a recombinant indicator cell line  Academic Article
• A novel, unusually efficacious duocarmycin carbamate prodrug that releases no residual byproduct  Academic Article
• A nuclear antigen associated with cell proliferation and blast transformation  Academic Article
• A nuclear hormone receptor-associated protein that inhibits transactivation by the thyroid-hormone and retinoic acid receptors  Academic Article
• A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects  Academic Article
• A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA  Academic Article
• A p47-phox pseudogene carries the most common mutation causing p47-phox-deficient chronic granulomatous disease  Academic Article
• A pRb-responsive, RGD-modified, and Hyaluronidase-armed Canine Oncolytic Adenovirus for Application in Veterinary Oncology  Academic Article
• A pandemic-enabled comparison of discovery platforms demonstrates a nai''ve antibody library can match the best immune-sourced antibodies  Academic Article
• A panel of igg1 b12 variants with selectively diminished or enhanced affinity for fc gamma receptors to define the role of effector functions in protection against hiv  Academic Article
• A panel of induced pluripotent stem cells from chimpanzees: a resource for comparative functional genomics  Academic Article
• A partnership between the dioxin receptor and a basic helix-loop-helix protein  Academic Article
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• A pathologic cascade leading to synaptic dysfunction in alpha-synuclein-induced neurodegeneration  Academic Article
• A patient of situs ambiguus with pancreatic head cancer successfully treated with gemcitabine and erlotinib  Academic Article
• A peptide core motif for binding to heterotrimeric G protein α subunits  Academic Article
• A peptide inhibitor of hiv-1 neutralizing antibody 2g12 is not a structural mimic of the natural carbohydrate epitope on gp120  Academic Article
• A peptoid "antibody surrogate" that antagonizes VEGF receptor 2 activity  Academic Article
• A peptoid antagonist of VEGF receptor 2 recognizes a 'hotspot' in the extracellular domain distinct from the hormone-binding site  Academic Article
• A ph sensitive colorometric assay for the high-throughput screening of enzyme inhibitors and substrates: A case study using kinases  Academic Article
• A phage display approach for rapid antibody humanization: designed combinatorial V gene libraries  Academic Article
• A pharmacokinetic and pharmacodynamic drug interaction study of acamprosate and naltrexone  Academic Article
• A pharmacological network for lifespan extension in Caenorhabditis elegans  Academic Article
• A phase 1 study of mapatumumab (fully human monoclonal antibody to TRAIL-R1) in patients with advanced solid malignancies  Academic Article
• A phase I/II trial of nimodipine for HIV-related neurologic complications  Academic Article
• A phase i clinical trial of the hu14.18-il2 (emd 273063) as a treatment for children with refractory or recurrent neuroblastoma and melanoma: A study of the children's oncology group  Academic Article
• A phase i/ib trial of murine monoclonal anti-gd2 antibody 14.G2a plus interleukin-2 in children with refractory neuroblastoma - a report of the children's cancer group  Academic Article
• A phase-i study of human mouse chimeric antiganglioside gd2 antibody ch14.18 in patients with neuroblastoma  Academic Article
• A phase-i study of neuroblastoma with the antiganglioside gd2 antibody 14.G2a  Academic Article
• A phenotypic high throughput screening assay for the identification of pharmacoperones for the gonadotropin releasing hormone receptor  Academic Article
• A phosphoproteomic analysis of the ErbB2 receptor tyrosine kinase signaling pathways  Academic Article
• A photoaffinity probe that targets folate-binding proteins  Academic Article
• A physical and functional link between splicing factors promotes pre-mRNA 3' end processing  Academic Article
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• A physical sciences network characterization of non-tumorigenic and metastatic cells  Academic Article
• A plant-like kinase in plasmodium falciparum regulates parasite egress from erythrocytes  Academic Article
• A plaque-specific antibody clears existing beta-amyloid plaques in Alzheimer's disease mice  Academic Article
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• A platform for functional assessment of large variant libraries in mammalian cells  Academic Article
• A platform for the discovery of new macrolide antibiotics  Academic Article
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• A polymorphism in the protease-like domain of apolipoprotein(a) is associated with severe coronary artery disease  Academic Article
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• A population response analysis approach to assign class II HLA-epitope restrictions  Academic Article
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• Aberrant multimeric structure of von Willebrand factor in a new variant of von Willebrand's disease (type IIC)  Academic Article
• Aberrant myofibril assembly in tropomodulin1 null mice leads to aborted heart development and embryonic lethality  Academic Article
• Aberrant protein S-nitrosylation contributes to the pathophysiology of neurodegenerative diseases  Academic Article
• Aberrant protein S-nitrosylation in neurodegenerative diseases  Academic Article
• Aberrant, persistent inclusion into lipid rafts limits the tumorigenic function of membrane type-1 matrix metalloproteinase in malignant cells  Academic Article
• Abeta localization in abnormal endosomes: Association with earliest Abeta elevations in AD and down syndrome  Academic Article
• Abl oncogene expression in non-hodgkin lymphomas: Correlation to histological differentiation and clinical status  Academic Article
• Ablating adenovirus type 5 fiber-car binding and hi loop insertion of the sigyplp peptide generate an endothelial cell-selective adenovirus  Academic Article
• Ablation of collagen VI leads to the release of platelets with altered function  Academic Article
• Abnormal auditory n100 amplitude: A heritable endophenotype in first-degree relatives of schizophrenia probands  Academic Article
• Abnormal expression of plasminogen activator inhibitors in patients with gestational trophoblastic disease  Academic Article
• Abnormal expression of type 1 plasminogen activator inhibitor and tissue factor in severe preeclampsia  Academic Article
• Abnormal immunoglobulin synthesis in monoclonal immunoglobulin light chain and light and heavy chain deposition disease  Academic Article
• Abnormal tau induces cognitive impairment through two different mechanisms: synaptic dysfunction and neuronal loss  Academic Article
• Abnormalities in the fibrinolytic system of the vascular wall associated with atherosclerosis  Academic Article
• Abnormalities of plasma cytokines and spleen in senile APP/PS1/Tau transgenic mouse model  Academic Article
• Abnormalities of pulmonary vascular dynamics and inflammation in early progressive systemic-sclerosis  Academic Article
• Abrupt closure - the caveat-i experience  Academic Article
• Abrupt vessel closure after directional coronary atherectomy  Academic Article
• Abrupt vessel closure complicating coronary angioplasty - clinical, angiographic and therapeutic profile  Academic Article
• Absence of G(i) proteins in the Sf9 insect cell. Characterization of the uncoupled recombinant N-formyl peptide receptor  Academic Article
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• Absence of increased in-hospital complications with reused balloon catheters  Academic Article
• Absence of lymphotoxic antibodies in patients with Yersinia-induced arthritis, Reiter syndrome and ankylosing-spondylitis  Academic Article
• Absence of nephritogenic gbm antigen(s) in some patients with hereditary nephritis  Academic Article
• Absence of specific mucosal antibody responses in hiv-exposed uninfected sex workers from the gambia  Academic Article
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• Academia-industry symbiosis in organic chemistry  Academic Article
• Academic cross-fertilization by public screening yields a remarkable class of protein phosphatase methylesterase-1 inhibitors  Academic Article
• Acamprosate  Academic Article
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• Acamprosate for alcohol dependence: A sex-specific meta-analysis based on individual patient data  Academic Article
• Acamprosate in the treatment of alcohol dependence  Academic Article
• Acamprosate in the treatment of alcohol dependence: clinical and economic considerations  Academic Article
• Acamprosate, alcoholism, and abstinence  Academic Article
• Acamprosate: a prototypic neuromodulator in the treatment of alcohol dependence  Academic Article
• Accelerated Clearance and Degradation of Cell-Free HIV by Neutralizing Antibodies Occurs via Fc gamma RIIb on Liver Sinusoidal Endothelial Cells by Endocytosis  Academic Article
• Accelerated plasminogen-activator dose regimens for coronary thrombolysis  Academic Article
• Accelerating next-generation vaccine development for global disease prevention  Academic Article
• Acceptability of the use of motivational interviewing to reduce underage drinking in a Native American community  Academic Article
• Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gpl120 is sterically restricted on primary human immunodeficiency virus type 1  Academic Article
• Access roads for RAG-ged terrains: Control of T cell receptor gene rearrangement at multiple levels  Academic Article
• Accessibility of nuclear chromatin by DNA binding polyamides  Academic Article
• Accessory genes confer a high replication rate to virulent feline immunodeficiency virus  Academic Article
• Accessory mutations maintain stability in drug-resistant HIV-1 protease  Academic Article
• Accommodating individual travel history and unsampled diversity in Bayesian phylogeographic inference of SARS-CoV-2  Academic Article
• Accommodating pathway information in expression quantitative trait locus analysis  Academic Article
• According to GOSPEL: filling in the GAP(DH) of NO-mediated neurotoxicity  Academic Article
• Accumulation of cyclin e is not a prerequisite for passage through the restriction point  Academic Article
• Accuracy of CT-based measurements of glenoid version for total shoulder arthroplasty  Academic Article
• Accuracy of haplotype frequency estimation for biallelic loci, via the expectation-maximization algorithm for unphased diploid genotype data  Academic Article
• Accurate detection and genotyping of snps utilizing population sequencing data  Academic Article
• Accurate prediction of deleterious protein kinase polymorphisms  Academic Article
• Acetylation of histone-like proteins of adenovirus type-5  Academic Article
• Acid beta-galactosidase - a developmentally-regulated marker of endocrine cell precursors in the human fetal pancreas  Academic Article
• Acitretin in psoriasis: An overview of adverse effects  Academic Article
• Acoustically detectable cellular-level lung injury induced by fluid mechanical stresses in microfluidic airway systems  Academic Article
• Acquired abnormalities of von Willebrand factor: facts to consider in patients with unexpected bleeding  Academic Article
• Acquired congenital heart block. Pattern of maternal antibody response to biochemically defined antigens of the SSA/Ro-SSB/La system in neonatal lupus  Academic Article
• Acquired resistance to cisplatin and doxorubicin in a small cell lung cancer cell line is correlated to elevated expression of glutathione-linked detoxification enzymes  Academic Article
• Acquired von Willebrand's disease in the myeloproliferative syndrome  Academic Article
• Actin assembly plays a variable, but not obligatory role in receptor-mediated endocytosis in mammalian cells  Academic Article
• Actinopolysporins a-c and tubercidin as a pdcd4 stabilizer from the halophilic actinomycete actinopolyspora erythraea yim 90600  Academic Article
• Action of RORs and their ligands in (patho)physiology  Academic Article
• Actionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations  Academic Article
• Actions of acute and chronic ethanol on presynaptic terminals  Academic Article
• Actions of redox-related congeners of nitric oxide at the NMDA receptor  Academic Article
• Activated integrin alpha v beta 3 cooperates with metalloproteinase MMP-9 in regulating migration of metastatic breast cancer cells  Academic Article
• Activated partial thromboplastin time and outcome after thrombolytic therapy for acute myocardial infarction: Results for the gusto-i trial  Academic Article
• Activated platelet-T-cell conjugates in peripheral blood of patients with HIV infection: coupling coagulation/inflammation and T cells  Academic Article
• Activated protein C  Academic Article
• Activated protein C alters cytosolic calcium flux in human brain endothelium via binding to endothelial protein C receptor and activation of protease activated receptor-1  Academic Article
• Activated protein C and inflammation in human myocardium after heart surgery  Academic Article
• Activated protein C and ischemic stroke  Academic Article
• Activated protein C in the cardioplegic solution on a porcine model of coronary ischemia-reperfusion has deleterious hemodynamic effects  Academic Article
• Activated protein C inhibits neutrophil extracellular trap formation in vitro and activation in vivo  Academic Article
• Activated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signaling in U937 cells  Academic Article
• Activated protein C mutant with minimal anticoagulant activity, normal cytoprotective activity, and preservation of thrombin activable fibrinolysis inhibitor-dependent cytoprotective functions  Academic Article
• Activated protein C plasma levels in the fasting and postprandial states among patients with previous unprovoked venous thromboembolism  Academic Article
• Activated protein C reduces graft neutrophil activation in clinical renal transplantation  Academic Article
• Activated protein C resistance caused by Arg506Gln mutation in factor Va  Academic Article
• Activated protein C resistance in ischemic stroke not due to factor V arginine(506)->glutamine mutation  Academic Article
• Activated protein C resistance: What have we learned now that the dust has settled?  Academic Article
• Activated protein C resistance: molecular mechanisms  Academic Article
• Activated protein C resistance: molecular mechanisms based on studies using purified Gln506-factor V  Academic Article
• Activated protein C variants with normal cytoprotective but reduced anticoagulant activity  Academic Article
• Activated protein C-dependent and -independent anticoagulant activities of protein S have different structural requirements  Academic Article
• Activated protein C: Potential therapy for severe sepsis, thrombosis, and stroke  Academic Article
• Activated protein C: biased for translation  Academic Article
• Activated protein c blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective  Academic Article
• Activated protein c correlates inversely with thrombin levels in resting healthy individuals  Academic Article
• Activated protein c in sepsis: The promise of nonanticoagulant activated protein c  Academic Article
• Activated protein c up-regulates procoagulant tissue factor activity on endothelial cells by shedding the tfpi kunitz 1 domain  Academic Article
• Activated protein c-cleaved protease activated receptor-1 is retained on the endothelial cell surface even in the presence of thrombin  Academic Article
• Activating pleiotropic receptors to kill cancer cells  Academic Article
• Activating transcription factor 4 increases chemotherapeutics resistance of human hepatocellular carcinoma  Academic Article
• Activation and complexation of protein C and cleavage and decrease of protein S in plasma of patients with intravascular coagulation  Academic Article
• Activation and function of gamma-delta t-cells  Academic Article
• Activation of AMP-activated protein kinase revealed by hydrogen/deuterium exchange mass spectrometry  Academic Article
• Activation of CD74 inhibits migration of human mesenchymal stem cells  Academic Article
• Activation of Hageman factor by proteases released during antigen challenge of human lung  Academic Article
• Activation of Hageman factor in solid and fluid phases. A critical role of kallikrein  Academic Article
• Activation of JNK3 alpha 1 requires both MKK4 and MKK7: Kinetic characterization of in vitro phosphorylated JNK3 alpha 1  Academic Article
• Activation of MPF in fission yeast  Academic Article
• Activation of angiogenic signaling pathways by two human tRNA synthetases  Academic Article
• Activation of c-myc gene expression by tumor-derived p53 mutants requires a discrete c-terminal domain  Academic Article
• Activation of c1 by monoclonal-antibodies directed against c1q  Academic Article
• Activation of cancer cell migration and invasion by ectopic synthesis of coagulation factor vii  Academic Article
• Activation of coagulation and angiogenesis in cancer - immunohistochemical localization in situ of clotting proteins and vascular endothelial growth factor in human cancer  Academic Article
• Activation of cyclin e/cdk2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin e  Academic Article
• Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes  Academic Article
• Activation of endothelial cell protease activated receptor 1 by the protein c pathway  Academic Article
• Activation of human complement by human lymphoid cells sensitized with histocompatibility alloantisera  Academic Article
• Activation of human effector cells by a tumor reactive recombinant anti-ganglioside gd(2) interleukin-2 fusion protein (ch14.18-il2)  Academic Article
• Activation of human factor-VII in plasma and in purified systems - roles of activated factor-IX, kallikrein, and activated factor-XII  Academic Article
• Activation of human peripheral-blood mononuclear-cells by anti-t3 - killing of tumor target-cells coated with anti-target-anti-t3 conjugates  Academic Article
• Activation of matrix metalloproteinase-9 (mmp-9) via a converging plasmin/stromelysin-1 cascade enhances tumor cell invasion  Academic Article
• Activation of methotrexate-alpha-alanine by carboxypeptidase-A monoclonal-antibody conjugate  Academic Article
• Activation of mitogen-activated protein kinases and p90 ribosomal s6 kinase in failing human hearts with dilated cardiomyopathy  Academic Article
• Activation of neutrophils by N-formyl chemotactic peptides  Academic Article
• Activation of nuclear receptor coactivator PGC-1 alpha by arginine methylation  Academic Article
• Activation of p38 in stimulated human neutrophils: Phosphorylation of the oxidase component p47(phox) by p38 and erk but not by jnk  Academic Article
• Activation of platelets in blood perfusing angioplasty-damaged coronary arteries. Flow cytometric detection  Academic Article
• Activation of preexisting t cell clones by targeted interleukin 2 therapy  Academic Article
• Activation of pro-uPA is critical for initial escape from the primary tumor and hematogenous dissemination of human carcinoma cells  Academic Article
• Activation of proMMP-9 by a plasmin/MMP-3 cascade in a tumor cell model. Regulation by tissue inhibitors of metalloproteinases  Academic Article
• Activation of protein C and hemodynamic recovery after coronary artery bypass surgery  Academic Article
• Activation of protein C during reperfusion in clinical liver transplantation  Academic Article
• Activation of rabbit tlr9 by different cpg-odn optimized for mouse and human tlr9  Academic Article
• Activation of resting lymphocytes-T by anti-CD3 (T3) antibodies in the absence of monocytes  Academic Article
• Activation of the HIF prolyl hydroxylase by the iron chaperones PCBP1 and PCBP2  Academic Article
• Activation of the Keap1/Nrf2 pathway for neuroprotection by electrophilic [correction of electrophillic] phase II inducers  Academic Article
• Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer  Academic Article
• Activation of the alpha7 nAChR reduces acid-induced acute lung injury in mice and rats  Academic Article
• Activation of the alternative complement pathway by ebv and the viral envelope glycoprotein, gp350  Academic Article
• Activation of the alternative complement pathway in systemic lupus erythematosus  Academic Article
• Activation of the alternative pathway of complement by antiserum to factor B  Academic Article
• Activation of the first component of human-complement, c1, by monoclonal-antibodies directed against different domains of subcomponent c1q  Academic Article
• Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation  Academic Article
• Activation of tumor cell integrin alpha(v)beta(3) controls angiogenesis and metastatic growth in the brain  Academic Article
• Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth  Academic Article
• Activation of urinary kallikrein in patients with interstitial cystitis  Academic Article
• Activation-independent platelet adhesion and aggregation under elevated shear stress  Academic Article
• Activation/division of lymphocytes results in increased levels of cytoplasmic activation/proliferation-associated protein-1: prototype of a new family of proteins  Academic Article
• Activators of the nuclear receptor ppar gamma enhance colon polyp formation  Academic Article
• Active and alkylated human agt structures: A novel zinc site, inhibitor and extrahelical base binding  Academic Article
• Active and inhibited human catalase structures: Ligand and nadph binding and catalytic mechanism  Academic Article
• Active ghrelin levels and active to total ghrelin ratio in cancer-induced cachexia  Academic Article
• Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations  Academic Article
• Active site modification of factor viia affects interactions of the protease domain with tissue factor  Academic Article
• Active site residues of cyclophilin A are crucial for its signaling activity via CD147  Academic Article
• Active site serine promotes stabilization of the reactive glutathione thiolate in rat glutathione transferase T2-2 - Evidence against proposed sulfatase activity of the corresponding human enzyme  Academic Article
• Active thymus derived suppressor lymphocytes in human cord blood  Academic Article
• Active-site residues governing high steroid isomerase activity in human glutathione transferase A3-3  Academic Article
• Actively transcribed genes in the raf oncogene group, located on the x-chromosome in mouse and human  Academic Article
• Activin enhances skin tumourigenesis and malignant progression by inducing a pro-tumourigenic immune cell response  Academic Article
• Activity of hoechst 33258 against Pneumocystis carinii f. sp muris, Candida albicans, and Candida dubliniensis  Academic Article
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• Activity-based labeling of matrix metalloproteinases in living vertebrate embryos  Academic Article
• Activity-based probes for proteomic profiling of histone deacetylase complexes  Academic Article
• Activity-based probes for the proteomic profiling of metalloproteases  Academic Article
• Activity-based probes that target diverse cysteine protease families  Academic Article
• Activity-based protein profiling for biochemical pathway discovery in cancer  Academic Article
• Activity-based protein profiling for the functional annotation of enzymes  Academic Article
• Activity-based protein profiling implicates urokinase activation as a key step in human fibrosarcoma intravasation  Academic Article
• Activity-based protein profiling in vivo using a copper(i)-catalyzed azide-alkyne 3+2 cycloaddition  Academic Article
• Activity-based protein profiling of oncogene-driven changes in metabolism reveals broad dysregulation of PAFAH1B2 and 1B3 in cancer  Academic Article
• Activity-based protein profiling of protein arginine methyltransferase 1  Academic Article
• Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474  Academic Article
• Activity-based protein profiling: From enzyme chemistry to proteomic chemistry  Academic Article
• Activity-based proteomics of enzyme superfamilies: Serine hydrolases as a case study  Academic Article
• Acute SIV infection of the brain leads to upregulation of IL6 ad interferon-regulated genes: expression patterns throughout disease progression and impact on neuroAIDS  Academic Article
• Acute and chronic effects of spirapril, alone or in combination with isradipine on kidney function and blood pressure in patients with reduced kidney function and hypertension  Academic Article
• Acute antihypertensive and renal effects of isradipine in hypertensive patients with normal and reduced renal function  Academic Article
• Acute coronary syndromes in the gusto-iib trial - prognostic insights and impact of recurrent ischemia  Academic Article
• Acute effects of alcohol on P300 in Asians with different ALDH2 genotypes  Academic Article
• Acute hemolysis after receiving oxaliplatin treatment: a case report and literature review  Academic Article
• Acute intervention during myocardial-infarction in patients with prior coronary-bypass surgery  Academic Article
• Acute intervention for myocardial-infarction  Academic Article
• Acute ischemic heart disease - cardiogenic shock complicating acute myocardial infarction: Predictors of death  Academic Article
• Acute monoblastic leukemia with skin nodules in an adult  Academic Article
• Acute myelofibrosis - treatment with allogeneic bone-marrow transplantation  Academic Article
• Acute myocardial infarction and complete bundle branch block at hospital admission: Clinical characteristics and outcome in the thrombolytic  Academic Article
• Acute neuroprotective synergy of erythropoietin and insulin-like growth factor I  Academic Article
• Acute renal failure in severe pancreatitis: a population-based study  Academic Article
• Acute-phase responses in transgenic mice with CNS overexpression of IL-1 receptor antagonist  Academic Article
• Acylcarnitines are anticoagulants that inhibit factor Xa and are reduced in venous thrombosis, based on metabolomics data  Academic Article
• Adaptation of a CCR5-using, primary human immunodeficiency virus type 1 isolate for CD4-independent replication  Academic Article
• Adaptation of energy metabolism in breast cancer brain metastases  Academic Article
• Adaptation of human immunodeficiency virus type 1 to cells expressing a binding-deficient CD4 mutant (lysine 46 to aspartic acid)  Academic Article
• Adaptation of influenza viruses to human airway receptors  Academic Article
• Adaptation of the bovine spongiform encephalopathy agent to primates and comparison with Creutzfeldt-- Jakob disease: implications for human health  Academic Article
• Adaptation, allometry, and hypertension  Academic Article
• Adaptations for the oxidation of polycyclic aromatic hydrocarbons exhibited by the structure of human P450 1A2  Academic Article
• Adapting proteostasis for disease intervention  Academic Article
• Adaptive boost target definition in high-risk head and neck cancer based on multi-imaging risk biomarkers  Academic Article
• Adaptive immune responses mediated by natural killer cells  Academic Article
• Adaptive partitioning QM/MM dynamics simulations for substrate uptake, product release, and solvent exchange  Academic Article
• Addiction as a stress surfeit disorder  Academic Article
• Addictions biology: Haplotype-based analysis for 130 candidate genes on a single array  Academic Article
• Adding amino acids with novel reactivity to the genetic code of Saccharomyces cerevisiae  Academic Article
• Addition of N-terminal peptide sequences activates the oncogenic and signaling potentials of the catalytic subunit p110α of phosphoinositide-3-kinase  Academic Article
• Addressing the medicinal chemistry bottleneck: a lean approach to centralized purification  Academic Article
• Adduction of cholesterol 5,6-secosterol aldehyde to membrane-bound myelin basic protein exposes an immunodominant epitope  Academic Article
• Adeno-associated virus enhances wild-type and oncolytic adenovirus spread  Academic Article
• Adeno-associated virus-mediated delivery of CRISPR-Cas systems for genome engineering in mammalian cells  Academic Article
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• Adenosine: a partial agonist of the growth hormone secretagogue receptor  Academic Article
• Adenoviral gene transfer of the interleukin-1 receptor antagonist protein to human islets prevents IL-1 beta-induced b-cell impairment and activation of islet cell apoptosis in vitro  Academic Article
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• Adenoviral transduction of human osteoblastic cell cultures - a new perspective for gene therapy of bone diseases  Academic Article
• Adenoviral transfer of the viral IL-10 gene periarticularly to mouse paws suppresses development of collagen-induced arthritis in both injected and uninjected paws  Academic Article
• Adenoviral-mediated transfer of tgf-beta 1 but not igf-1 induces chondrogenic differentiation of human mesenchymal stem cells in pellet cultures  Academic Article
• Adenovirus chromatin structure at different stages of infection  Academic Article
• Adenovirus composition, proteolysis, and disassembly studied by in-depth qualitative and quantitative proteomics  Academic Article
• Adenovirus core protein pvii is translocated into the nucleus by multiple import receptor pathways  Academic Article
• Adenovirus endocytosis requires actin cytoskeleton reorganization mediated by rho family gtpases  Academic Article
• Adenovirus endocytosis via alpha(v) integrins requires phosphoinositide-3-oh kinase  Academic Article
• Adenovirus fiber shaft contains a trimerization element that supports peptide fusion for targeted gene delivery  Academic Article
• Adenovirus interaction with distinct integrins mediates separate events in cell entry and gene delivery to hematopoietic cells  Academic Article
• Adenovirus internalization and infection require dynamin  Academic Article
• Adenovirus membrane penetration: Tickling the tail of a sleeping dragon  Academic Article
• Adenovirus protein vi mediates membrane disruption following capsid disassembly  Academic Article
• Adenovirus serotype 5 fiber shaft influences in vivo gene transfer in mice  Academic Article
• Adenovirus tales: from the cell surface to the nuclear pore complex  Academic Article
• Adenovirus type 5 viral particles pseudotyped with mutagenized fiber proteins show diminished infectivity of coxsackie b-adenovirus receptor-bearing cells  Academic Article
• Adenovirus vector pseudotyping in fiber-expressing cell lines: Improved transduction of epstein-barr virus-transformed b cells  Academic Article
• Adenovirus-mediated direct gene therapy with bone morphogenetic protein-2 produces bone  Academic Article
• Adenovirus-mediated gene transfer of insulin-like growth factor 1 stimulates proteoglycan synthesis in rabbit joints  Academic Article
• Adenovirus-mediated gene transfer of the beta(2)-adrenergic receptor to donor hearts enhances cardiac function  Academic Article
• Adhesion and fusion efficiencies of human immunodeficiency virus type 1 (HIV-1) surface proteins  Academic Article
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• Adhesive interactions between human neural stem cells and inflamed human vascular endothelium are mediated by integrins  Academic Article
• Adhesive properties of the isolated amino-terminal domain of platelet glycoprotein Ib alpha in a flow field  Academic Article
• Adhesive receptor mac-1 coordinates the activation of factor x on stimulated cells of monocytic and myeloid differentiation: An alternative initiation of the coagulation protease cascade  Academic Article
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• Adipose tissue as a modulator of clinical inflammation: Does obesity reduce the prevalence of rheumatoid arthritis?  Academic Article
• Adjunctive therapy for percutaneous revascularization in acute myocardial infarction  Academic Article
• Adjuncts to thrombolysis for myocardial reperfusion  Academic Article
• Adjuvanted H5N1 influenza vaccine enhances both cross-reactive memory B cell and strain-specific naive B cell responses in humans  Academic Article
• Admixture and clinical phenotypic variation  Academic Article
• Admixture mapping as a gene discovery approach for complex human traits and diseases  Academic Article
• Adolescent ethanol exposure: Does it produce long-lasting electrophysiological effects?  Academic Article
• Adolescents and Young Adults with Life-Threatening Illness Special Considerations, Transitions in Care, and the Role of Pediatric Palliative Care  Academic Article
• Adoptive immunotherapy induces cns dendritic cell recruitment and antigen presentation during clearance of a persistent viral infection  Academic Article
• Adoptive transfer of human lymphoid cells to severely immunodeficient mice: models for normal human immune function, autoimmunity, lymphomagenesis, and AIDS  Academic Article
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• Adp-ribosylation factor is required for vesicular trafficking between the endoplasmic-reticulum and the cis-golgi compartment  Academic Article
• Adrenal metastases in lung cancer: clinical implications of a mathematical model  Academic Article
• Adrenaline binding-site on human-platelets  Academic Article
• Adrenergic beta-1 receptor genetic variation predicts longitudinal rate of GFR decline in hypertensive nephrosclerosis  Academic Article
• Adrenocortical function and suicidal behavior in depressive disorders  Academic Article
• Adult chicken alpha-globin gene-expression in transfected qt6 quail cells - evidence for a negative regulatory element in the alpha-d gene region  Academic Article
• Adult neurogenesis: Can analysis of cell cycle proteins move us "Beyond BrdU"?  Academic Article
• Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19  Academic Article
• Advances and challenges in hemophilic arthropathy  Academic Article
• Advances in Analysis of Low Signal-to-Noise Images Link Dynamin and AP2 to the Functions of an Endocytic Checkpoint  Academic Article
• Advances in GPCR modeling evaluated by the GPCR Dock 2013 assessment: meeting new challenge  Academic Article
• Advances in b-cell epitope analysis of autoantigens in connective tissue diseases  Academic Article
• Advances in human proteomics at high scale with the SOMAscan proteomics platform  Academic Article
• Advances in multifunctional glycosylated nanomaterials: preparation and applications in glycoscience  Academic Article
• Advances in multiplex nucleic acid diagnostics for blood-borne pathogens: promises and pitfalls-an update  Academic Article
• Advances in pain therapeutics  Academic Article
• Advances in polyketide synthase structure and function  Academic Article
• Advances in reprogramming-based study of neurologic disorders  Academic Article
• Advances in structure-based vaccine design  Academic Article
• Advances in targeting nucleocapsid-nucleic acid interactions in HIV-1 therapy  Academic Article
• Advances in the chemistry of transplantation antigens  Academic Article
• Advances in the pharmacotherapy of alcoholism: Challenging misconceptions  Academic Article
• Advances in the treatment of Clostridium difficile with fidaxomicin: a narrow spectrum antibiotic  Academic Article
• Advances in thrombolytic therapy for acute myocardial-infarction  Academic Article
• Advances in treatment and management: Immunologic and cell-based regenerative therapies  Academic Article
• Advances in understanding the complex mechanisms of DNA interstrand cross-link repair  Academic Article
• Advancing a neurodevelopmental origin for schizophrenia  Academic Article
• Advancing biological understanding and therapeutics discovery with small-molecule probes  Academic Article
• Advancing cancer patient care by integrating circulating tumor cell technology to understand the spatial and temporal dynamics of cancer  Academic Article
• Advancing computational biology and bioinformatics research through open innovation competitions  Academic Article
• Adverse effects of adenovirus-mediated gene transfer of human transforming growth factor beta 1 into rabbit knees  Academic Article
• Adverse events to antiretrovirals in the Swiss HIV Cohort Study: Effect on mortality and treatment modification  Academic Article
• Adverse reactions to iopamidol and iohexol myelography with special attention to headache - role of myelographic technique  Academic Article
• Affective erp processing in a visual oddball task: Arousal, valence, and gender  Academic Article
• Affective picture processing: An integrative review of erp findings  Academic Article
• Affective recognition memory processing and event-related brain potentials  Academic Article
• Affective valence, stimulus attributes, and p300: Color vs. Black/white and normal vs. Scrambled images  Academic Article
• Affective visual event-related potentials: Arousal, repetition, and time-on-task  Academic Article
• Affective visual event-related potentials: Arousal, valence, and repetition effects for normal and distorted pictures  Academic Article
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• Affinity labeling, molecular cloning, and comparative amino acid sequence analyses of sex steroid-binding protein of plasma. A multidisciplinary approach for understanding steroid-protein interaction and its physiological role  Academic Article
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• Affinity maturation of leukemia inhibitory factor and conversion to potent antagonists of signaling  Academic Article
• Affinity modulation of the alpha IIb beta 3 integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor  Academic Article
• Affinity-based assay of Rho guanosine triphosphatase activation  Academic Article
• Affinity-based ranking of ligands for DPP-4 from mixtures  Academic Article
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• Ag(c) - recognition by a monoclonal-antibody  Academic Article
• Age and outcome after acute coronary syndromes without persistent st-segment elevation  Academic Article
• Age and outcome with contemporary thrombolytic therapy - results from the gusto-i trial  Academic Article
• Age at first intoxication and alcohol use disorders in southwest California Indians  Academic Article
• Age of first marijuana use and the occurrence of marijuana use disorders in Southwest California Indians  Academic Article
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• Age- and dose-related effects on msc engraftment levels and anatomical distribution in the central nervous systems of nonhuman primates: Identification of novel msc subpopulations that respond to guidance cues in brain  Academic Article
• Age- and site-associated biomechanical weakening of human articular cartilage of the femoral condyle  Academic Article
• Age-associated bidirectional modulation of gene expression in single identified R15 neuron of Aplysia  Academic Article
• Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages  Academic Article
• Age-dependent inverse correlations in CSF and plasma amyloid-β(1-42) concentrations prior to amyloid plaque deposition in the brain of 3xTg-AD mice  Academic Article
• Age-independent and age-related deficits in visuospatial learning, sleep-wake states, thermoregulation and motor activity in PDAPP mice  Academic Article
• Age-related oxidative modifications of transthyretin modulate its amyloidogenicity  Academic Article
• Age-related somatic structural changes in the nuclear genome of human blood cells  Academic Article
• Age-related thymic activity in adults following chemotherapy-induced lymphopenia  Academic Article
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• Aging-related concerns and body-image - possible future implications for eating disorders  Academic Article
• Aging-related differences in chondrocyte viscoelastic properties  Academic Article
• Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis  Academic Article
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• Agonist antibody that induces human malignant cells to kill one another  Academic Article
• Agonist-bound structure of the human P2Y(12) receptor  Academic Article
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• Analysis of effector-cells in human antibody-dependent cellular cytotoxicity with murine monoclonal-antibodies  Academic Article
• Analysis of gene expression identifies candidate markers and pharmacological targets in prostate cancer  Academic Article
• Analysis of hapten binding and catalytic determinants in a family of catalytic antibodies  Academic Article
• Analysis of human cytochrome P4502C8 substrate specificity using a substrate pharmacophore and site-directed mutants  Academic Article
• Analysis of large-scale mutagenesis data to assess the impact of single amino acid substitutions  Academic Article
• Analysis of lipopolysaccharide-binding by cd14  Academic Article
• Analysis of microRNAs expressions in chondrosarcoma  Academic Article
• Analysis of microtubule dynamic instability using a plus-end growth marker  Academic Article
• Analysis of naturally processed peptides eluted from HLA DRB1*0402 and *0404  Academic Article
• Analysis of neutralization specificities in polyclonal sera derived from human immunodeficiency virus type 1-infected individuals  Academic Article
• Analysis of nuclear protein import and export in vitro using fluorescent cargoes  Academic Article
• Analysis of o-glycan heterogeneity in iga1 myeloma proteins by fourier transform ion cyclotron resonance mass spectrometry: Implications for iga nephropathy  Academic Article
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• Analysis of platelet aggregation disorders based on flow cytometric analysis of membrane glycoprotein IIb-IIIa with conformation-specific monoclonal antibodies  Academic Article
• Analysis of protein arginine methylation and protein arginine-methyltransferase activity  Academic Article
• Analysis of protein-S C4b-binding protein interactions by homology modeling and inhibitory antibodies  Academic Article
• Analysis of result variability from high-density oligonucleotide arrays comparing same-species and cross-species hybridizations  Academic Article
• Analysis of risk of bleeding complications after different doses of aspirin in 192,036 patients enrolled in 31 randomized controlled trials  Academic Article
• Analysis of secondary structural elements in human microRNA hairpin precursors  Academic Article
• Analysis of stimulation-inhibition paradox exhibited by lymphocytes exposed to concanavalin-a  Academic Article
• Analysis of stop-gain and frameshift variants in human innate immunity genes  Academic Article
• Analysis of structure-function relationships in the platelet membrane glycoprotein Ib-binding domain of von Willebrand's factor by expression of deletion mutants  Academic Article
• Analysis of the S3 and S3' subsite specificities of feline immunodeficiency virus (FIV) protease: development of a broad-based protease inhibitor efficacious against FIV, SIV, and HIV in vitro and ex vivo  Academic Article
• Analysis of the autoantibody response to fibrillarin in human disease and murine models of autoimmunity  Academic Article
• Analysis of the epitopes of proliferating cell nuclear antigen recognized by monoclonal antibodies  Academic Article
• Analysis of the gene expression profile activated by the CC chemokine ligand 5/RANTES and by lipopolysaccharide in human monocytes  Academic Article
• Analysis of the genome sequence of the flowering plant Arabidopsis thaliana  Academic Article
• Analysis of the hormone-dependent regulation of a JunD-estrogen receptor chimera  Academic Article
• Analysis of the human immunodeficiency virus type 1 gp41 membrane proximal external region arrayed on hepatitis b surface antigen particles  Academic Article
• Analysis of the interaction of antibodies with a conserved, enzymatically deglycosylated core of the hiv type 1 envelope glycoprotein 120  Academic Article
• Analysis of the interaction of the human immunodeficiency virus type 1 gp120 envelope glycoprotein with the gp41 transmembrane glycoprotein  Academic Article
• Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for beta-Pix in negative regulation of focal adhesion maturation  Academic Article
• Analysis of the neutralization breadth of the anti-v3 antibody f425-b4e8 and re-assessment of its epitope fine specificity by scanning mutagenesis  Academic Article
• Analysis of the relative level of gene expression from different retroviral vectors used for gene therapy  Academic Article
• Analysis of the therapeutic functions of novel melanocortin receptor agonists in mc3r-and mc4r-deficient c57bl/6j mice  Academic Article
• Analysis of the weak interactions of adp-unc104 and adp-kinesin with microtubules and their inhibition by map2c  Academic Article
• Analysis of transient structures by cryomicroscopy combined with rapid mixing of spray droplets  Academic Article
• Analysis of translational initiation in coxsackievirus b3 suggests an alternative explanation for the high frequency of r+4 in the eukaryotic consensus motift  Academic Article
• Analysis of tryptic peptides from the C-terminal region of alpha-crystallin from cataractous and normal human lenses  Academic Article
• Analysis of tumor necrosis factor promoter responses to ultraviolet light  Academic Article
• Analytical platforms for activity-based protein profiling - exploiting the versatility of chemistry for functional proteomics  Academic Article
• Analyzing and tuning ribozyme activity by deep sequencing to modulate gene expression level in mammalian cells  Academic Article
• Anaphylactic release of a prekallikrein activator from human lung in vitro  Academic Article
• Anas in systemic rheumatic disease. Diagnostic significance  Academic Article
• Anatomical location of LPA1 activation and LPA phospholipid precursors in rodent and human brain  Academic Article
• Anatomical posterior cruciate ligament transplantation: a biomechanical analysis  Academic Article
• Anatomy of cd1-lipid antigen complexes  Academic Article
• Anatomy of viral persistence  Academic Article
• Anatomy of viral persistence: mechanisms of persistence and associated disease  Academic Article
• Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase  Academic Article
• Ancient noncoding elements conserved in the human genome  Academic Article
• Ancient vertebrate conserved noncoding elements have been evolving rapidly in teleost fishes  Academic Article
• Androgen receptor is overexpressed in boys with severe hypospadias, and ZEB1 regulates androgen receptor expression in human foreskin cells  Academic Article
• Androgen receptor splice variants determine taxane sensitivity in prostate cancer  Academic Article
• Androgen receptor upregulation mediates radioresistance after ionizing radiation  Academic Article
• Anecortave acetate as monotherapy for the treatment of subfoveal lesions in patients with exudative age-related macular degeneration (amd) - interim (month 6) analysis of clinical safety and efficacy  Academic Article
• Anecortave acetate as monotherapy for treatment of subfoveal neovascularization in age-related macular degeneration - twelve-month clinical outcomes  Academic Article
• Anergy induction in encephalitogenic t-cells by brain microvessel endothelial-cells is inhibited by interleukin-1  Academic Article
• Anesthesia does not increase opioid peptides in cerebrospinal fluid of humans  Academic Article
• Aneuploid mosaicism in the developing and adult cerebellar cortex  Academic Article
• Aneuploidy in the normal and diseased brain  Academic Article
• Angiogenic capacity of M1-and M2-polarized macrophages is determined by the levels of TIMP-1 complexed with their secreted proMMP-9  Academic Article
• Angiographic adverse events, creatine kinase-mb elevation, and ischemic end points complicating percutaneous coronary intervention (a replace-2 substudy)  Academic Article
• Angiographic findings and outcome in diabetic patients treated with thrombolytic therapy for acute myocardial infarction: The gusto-i experience  Academic Article
• Angiographic variables predict increased risk for adverse ischernic events after coronary stenting with glycoprotein iib/iiia inhibition - results from the target trial  Academic Article
• Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor  Academic Article
• Angiomotin regulates endothelial cell migration during embryonic angiogenesis  Academic Article
• Angioplasty or thrombolysis in acute myocardial-infarction - dilate or dissolve  Academic Article
• Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity  Academic Article
• Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus  Academic Article
• Angiotensin-converting enzyme 2: A functional receptor for SARS coronavirus  Academic Article
• Angiotensin-converting enzyme gene polymorphism predicts the time-course of blood pressure response to angiotensin converting enzyme inhibition in the aask trial  Academic Article
• Angiotensin-converting enzyme inhibition with enalapril slows progressive intima-media thickening of the common carotid artery in patients with non-insulin-dependent diabetes mellitus  Academic Article
• Angucyclines and angucyclinones from streptomyces sp. CB01913 featuring C-ring cleavage and expansion  Academic Article
• Animal cytokinesis: breaking up is hard to do  Academic Article
• Animal models for retrovirus-induced immunodeficiency disease  Academic Article
• Animal models of craving: a roundtable discussion  Academic Article
• Animal models of human amyloidoses: Are transgenic mice worth the time and trouble?  Academic Article
• Animal models used to examine the role of the environment in the development of autoimmune disease: Findings from an NIEHS Expert Panel Workshop  Academic Article
• Animal origins of the severe acute respiratory syndrome coronavirus: Insight from ACE2-S-protein interactions  Academic Article
• Animal-models of drug craving  Academic Article
• Anion shielding of electrostatic repulsions in transthyretin modulates stability and amyloidosis: Insight into the chaotrope unfolding dichotomy  Academic Article
• Annotating STEAP1 regulation in prostate cancer with (89)Zr immuno-PET  Academic Article
• Annotating individual human genomes  Academic Article
• Another HIV vaccine failure: where to next?  Academic Article
• Another activation switch for endothelial nitric oxide synthase: Why does it have to be so complicated?  Academic Article
• Antagonism of c-IAP and XIAP proteins is required for efficient induction of cell death by small-molecule IAP antagonists  Academic Article
• Antagonism of the histamine H-4 receptor reduces LPS-induced TNF production in vivo  Academic Article
• Antagonistic action of pitrazepin on human and rat gaba(a) receptors  Academic Article
• Antagonists of inhibitor of apoptosis proteins based on thiazole amide isosteres  Academic Article
• Antagonists of the kappa opioid receptor  Academic Article
• Anterior cruciate ligament changes in the human knee joint in aging and osteoarthritis  Academic Article
• Anterior medial temporal lobe volumes in polydipsic schizophrenic patients with and without hypo-osmolemia: A pilot study  Academic Article
• Anthropometric measures at multiple times throughout life and prostate cancer diagnosis, metastasis, and death  Academic Article
• Anti-CS1 humanized monoclonal antibody HuLuc63 inhibits myeloma cell adhesion and induces aritibody-dependent cellular cytotoxicity in the bone marrow mitieu  Academic Article
• Anti-DFS70 antibodies in 597 healthy hospital workers  Academic Article
• Anti-DNA antibodies are a major component of the intrathecal B cell response in multiple sclerosis  Academic Article
• Anti-HIV B Cell lines as candidate vaccine biosensors  Academic Article
• Anti-HIV-1 gene expressing lentiviral vectors as an adjunctive therapy for HIV-1 infection  Academic Article
• Anti-IFN-alpha/beta receptor antibody treatment ameliorates disease in lupus-predisposed mice  Academic Article
• Anti-LRP/LR specific antibodies and shRNAs impede amyloid beta shedding in Alzheimer's disease  Academic Article
• Anti-LRP/LR specific antibody IgG1-iS18 and knock-down of LRP/LR by shRNAs rescue cells from A beta(42) induced cytotoxicity  Academic Article
• Anti-LRP/LR specific antibody IgG1-iS18 and knock-down of LRP/LR by shRNAs rescue cells from Aβ42 induced cytotoxicity  Academic Article
• Anti-acetylcholine receptor fab fragments isolated from thymus-derived phage display libraries from myasthenia gravis patients reflect predominant specificities in serum and block the action of pathogenic serum antibodies  Academic Article
• Anti-alpha1(IV) collagen autoantibodies associated with lung adenocarcinoma presenting as the Goodpasture syndrome  Academic Article
• Anti-apoprotein-b monoclonal-antibodies detect human low-density lipoprotein polymorphism  Academic Article
• Anti-apoptotic peptides protect against radiation-induced cell death  Academic Article
• Anti-cd14 mab treatment provides therapeutic benefit after in vivo exposure to endotoxin  Academic Article
• Anti-cocaine vaccine based on coupling a cocaine analog to a disrupted adenovirus  Academic Article
• Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPAR gamma by Cdk5  Academic Article
• Anti-formyl peptide antibodies  Academic Article
• Anti-gd2 antibody with gm-csf, interleukin-2, and isotretinoin for neuroblastoma  Academic Article
• Anti-glomerular basement-membrane antibody-induced glomerulonephritis  Academic Article
• Anti-glomerular basement-membrane antibody-mediated glomerulonephritis and goodpastures-syndrome  Academic Article
• Anti-gravity treadmills are effective in reducing knee forces  Academic Article
• Anti-hla antibodies of predetermined specificity - a chemically synthesized peptide induces antibodies specific for hla-a,b heavy-chain  Academic Article
• Anti-human immunodeficiency virus type 1 (hiv-1) antibodies 2f5 and 4e10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize hiv-1  Academic Article
• Anti-inflammatory activity in vitro and in vivo of the protein farnesyltransferase inhibitor tipifarnib  Academic Article
• Anti-inflammatory effect of transforming growth factor-beta 1 in myoblast transplantation  Academic Article
• Anti-inflammatory, antithrombotic, and neuroprotective effects of activated protein C in a murine model of focal ischemic stroke  Academic Article
• Anti-laminin reactivity and glomerular immune deposition by in vitro recombinant antibodies  Academic Article
• Anti-lung cancer activity and inhibitory mechanisms of a novel Calothrixin A derivative  Academic Article
• Anti-native DNA antibodies from autoimmune sera also bind to DNA in mitochondria  Academic Article
• Anti-peptide antibodies detect oncogene-related proteins in urine  Academic Article
• Anti-platelet therapy in the prevention of hepatitis B virus-associated hepatocellular carcinoma  Academic Article
• Anti-proliferative actions of a synthetic REV-ERBα/β agonist in breast cancer cells  Academic Article
• Anti-repression of RNA polymerase II transcription by pyrrole-imidazole polyamides  Academic Article
• Anti-sm and anti-DNA antibodies in paired serum and synovial-fluid samples from patients with sle  Academic Article
• Anti-thromboxane-a2 actions of pinane thromboxane-a2 derivatives  Academic Article
• Anti-tissue antibodies in rheumatic disease: standardization and nomenclature  Academic Article
• Anti-toxin antibodies in prophylaxis and treatment of inhalation anthrax  Academic Article
• Anti-tumor and immunomodulatory activity of resveratrol in vitro and its potential for combining with cancer immunotherapy  Academic Article
• Anti-tumor promoting effects of palmitoyl: protein thioesterase inhibitors against a human neurotumor cell line  Academic Article
• Antiapoptotic role of the p38 mitogen-activated protein kinase-myocyte enhancer factor 2 transcription factor pathway during neuronal differentiation  Academic Article
• Antibacterial activity of REP8839, a new antibiotic for topical use  Academic Article
• Antibacterial cyclic D,L-alpha-glycopeptides  Academic Article
• Antibacterial effect of human mesenchymal stem cells is mediated in part from secretion of the antimicrobial peptide LL-37  Academic Article
• Antibodies against hiv-1 from phage display libraries: Mapping of an immune response and progress towards antiviral immunotherapy  Academic Article
• Antibodies against synthetic peptides react with the 2nd epstein-barr virus-associated nuclear antigen  Academic Article
• Antibodies against viruses: passive and active immunization  Academic Article
• Antibodies for the immunochemistry of the human beta-3-adrenergic receptor  Academic Article
• Antibodies from Rabbits Immunized with HIV-1 Clade B SOSIP Trimers Can Neutralize Multiple Clade B Viruses by Destabilizing the Envelope Glycoprotein  Academic Article
• Antibodies from combinatorial libraries use functional receptor pleiotropism to regulate cell fates  Academic Article
• Antibodies from patients with mixed connective tissue disease react with heterogeneous nuclear ribonucleoprotein or ribonucleic acid (hnRNP/RNA) of the nuclear matrix  Academic Article
• Antibodies have the intrinsic capacity to destroy antigens  Academic Article
• Antibodies in human infectious disease  Academic Article
• Antibodies of predetermined specificity against chemically synthesized peptides of human interleukin-2  Academic Article
• Antibodies of predetermined specificity for the nh2 terminus of a cellular protein p53 react with the native molecule - evidence for the presence of different p53s  Academic Article
• Antibodies of predetermined specificity in biology and medicine  Academic Article
• Antibodies reacting with ribosomal ribonucleoprotein in connective tissue diseases  Academic Article
• Antibodies reactive to non-hla antigens in transplant glomerulopathy  Academic Article
• Antibodies reactive with cell-surface carbohydrates  Academic Article
• Antibodies that cross-neutralize the tier-2 pseudoviruses are produced in antiretroviral-naive HIV-1-infected children from northern India  Academic Article
• Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike  Academic Article
• Antibodies to a nuclear nucleolar antigen in patients with polymyositis overlap syndromes  Academic Article
• Antibodies to cellular antigens in Sjögren's syndrome  Academic Article
• Antibodies to histones in drug-induced and idiopathic lupus erythematosus  Academic Article
• Antibodies to histones in systemic lupus erythematosus: prevalence, specificity, and relationship to clinical and laboratory features  Academic Article
• Antibodies to microtubule-associated protein 2 in patients with neuropsychiatric systemic lupus erythematosus  Academic Article
• Antibodies to oral mucosa in patients with ocular Behcet's disease  Academic Article
• Antibodies to peptides detect new hepatitis-b antigen - serological correlation with hepatocellular-carcinoma  Academic Article
• Antibodies to the alpha-v-beta-3 integrin label a protein concentrated in brain synaptosomal membranes  Academic Article
• Antibody - the flexible adapter molecule  Academic Article
• Antibody 17b binding at the coreceptor site weakens the kinetics of the interaction of envelope glycoprotein gp120 with cd4  Academic Article
• Antibody 2g12 recognizes di-mannose equivalently in domain- and nondomain-exchanged forms but only binds the hiv-1 glycan shield if domain exchanged  Academic Article
• Antibody 8ANC195 reveals a site of broad vulnerability on the HIV-1 envelope spike  Academic Article
• Antibody Engineering & Therapeutics 2015: The Antibody Society's annual meeting December 7-10, 2015, San Diego, CA  Academic Article
• Antibody Libraries as Tools to Discover Functional Antibodies and Receptor Pleiotropism  Academic Article
• Antibody against megakaryocytes in idiopathic thrombocytopenic purpura  Academic Article
• Antibody against the leu-cam beta-chain (cd18) promotes both lfa-1-dependent and cr3-dependent adhesion events  Academic Article
• Antibody and virus: Binding and neutralization  Academic Article
• Antibody catalysis of the oxidation of water  Academic Article
• Antibody conjugates with morpholinodoxorubicin and acid-cleavable linkers  Academic Article
• Antibody conjugates with unnatural amino acids  Academic Article
• Antibody conjugation approach enhances breadth and potency of neutralization of anti-HIV-1 antibodies and CD4-IgG  Academic Article
• Antibody conjugation via one and two C-terminal selenocysteines  Academic Article
• Antibody detection using tumor-associated antigen mini-array in immunodiagnosing human hepatocellular carcinoma  Academic Article
• Antibody domain exchange is an immunological solution to carbohydrate cluster recognition  Academic Article
• Antibody elicited against the gp41 N-heptad repeat (NHR) coiled-coil can neutralize HIV-1 with modest potency but non-neutralizing antibodies also bind to NHR mimetics  Academic Article
• Antibody engineering & therapeutics, the annual meeting of the antibody society December 7-10, 2015, San Diego, CA, USA  Academic Article
• Antibody engineering and therapeutics conference The annual meeting of the antibody society, Huntington Beach, CA, December 7-11, 2014  Academic Article
• Antibody engineering and therapeutics, The Annual Meeting of the Antibody Society: December 8-12, 2013, Huntington Beach, CA  Academic Article
• Antibody evolution constrains conformational heterogeneity by tailoring protein dynamics  Academic Article
• Antibody humanization using monovalent phage display  Academic Article
• Antibody mapping of tissue factor implicates 2 different exon-encoded regions in function  Academic Article
• Antibody microarrays utilizing site-specific antibody-oligonucleotide conjugates  Academic Article
• Antibody modeling assessment II. Structures and models  Academic Article
• Antibody neutralization epitopes and integrin binding sites on nonenveloped viruses  Academic Article
• Antibody neutralization of HIV-1  Academic Article
• Antibody neutralization of hiv-1 and the potential for vaccine design  Academic Article
• Antibody neutralization-resistant primary isolates of human immunodeficiency virus type 1  Academic Article
• Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env  Academic Article
• Antibody protects macaques against vaginal challenge with a pathogenic r5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro  Academic Article
• Antibody recognition of a carbohydrate epitope: a template for HIV vaccine design  Academic Article
• Antibody recognition of a highly conserved influenza virus epitope  Academic Article
• Antibody recognition of the pandemic H1N1 Influenza virus hemagglutinin receptor binding site  Academic Article
• Antibody responses against SARS coronavirus are correlated with disease outcome of infected individuals  Academic Article
• Antibody responses in melanoma patients immunized with an anti-idiotype antibody mimicking disialoganglioside gd2  Academic Article
• Antibody responses to envelope glycoproteins in HIV-1 infection  Academic Article
• Antibody structure and molecular immunology  Academic Article
• Antibody structure and molecular immunology  Academic Article
• Antibody structure, diversity, and specificity  Academic Article
• Antibody targeted drugs as cancer therapeutics  Academic Article
• Antibody to gp41 MPER alters functional properties of HIV-1 Env without complete neutralization  Academic Article
• Antibody vs. HIV in a clash of evolutionary titans  Academic Article
• Antibody-antigen interactions - new structures and new conformational-changes  Academic Article
• Antibody-coated protein a-bearing staphylococcus-aureus - versatile and stable immune reagent  Academic Article
• Antibody-dependent cell-mediated cytotoxicity effector-enhanced EphA2 agonist monoclonal antibody demonstrates potent activity against human tumors  Academic Article
• Antibody-dependent cellular cytotoxicity against murine leukemia viral-antigens - studies with human lymphoblastoid cell lines and human peripheral lymphocytes as effector cells comparing rabbit, goat, and mouse antisera  Academic Article
• Antibody-dependent lymphocytotoxicity induced by immunoglobulin-g from hodgkins-disease splenic lymphocytes  Academic Article
• Antibody-drug conjugate library prepared by scanning insertion of the aldehyde tag into IgG1 constant regions  Academic Article
• Antibody-drug conjugates (ADCs) derived from interchain cysteine cross-linking demonstrate improved homogeneity and other pharmacological properties over conventional heterogeneous ADCs  Academic Article
• Antibody-il-12 fusion proteins are effective in scid mouse models of prostate and colon carcinoma metastases  Academic Article
• Antibody-independent activation of the alternative complement pathway by measles virus-infected cells  Academic Article
• Antibody-induced redistribution of measles-virus antigens on cell-surface  Academic Article
• Antibody-interleukin 2 fusion proteins: A new approach to cancer therapy  Academic Article
• Antibody-mediated neutralization of ebola virus can occur by two distinct mechanisms  Academic Article
• Antibody-recruiting molecules: an emerging paradigm for engaging immune function in treating human disease  Academic Article
• Antibody-targeted interleukin-2 stimulates t-cell killing of autologous tumor-cells  Academic Article
• Anticancer properties of distinct antimalarial drug classes  Academic Article
• Anticholinergic potency of psychoactive drugs in human and rat cerebral cortex and striatum  Academic Article
• Anticoagulant dysfunction of human Arg352Trp-activated protein C caused by defective factor Va inactivation  Academic Article
• Anticoagulant protein-C pathway defective in majority of thrombophilic patients  Academic Article
• Anticoagulant response to activated protein-C- method validation and assay comparison  Academic Article
• Anticoagulant synergism of heparin and activated protein C in vitro - role of a novel anticoagulant mechanism of heparin, enhancement of inactivation of factor V by activated protein C  Academic Article
• Anticodon G recognition by tRNA synthetases mimics the tRNA core  Academic Article
• Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor  Academic Article
• Anticytokine gene therapy of autoimmune diseases  Academic Article
• Anticytoplasmic antibodies in antinuclear antibody-negative lupus erythematosus. Correlation with clinical course  Academic Article
• Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation  Academic Article
• Antidiabetic phospholipid-nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation  Academic Article
• Antifungal azoles: structural insights into undesired tight binding to cholesterol-metabolizing CYP46A1  Academic Article
• Antigen compartmentation and t helper cell tolerance induction  Academic Article
• Antigen delivery to macrophages using liposomal nanoparticles targeting sialoadhesin/cd169  Academic Article
• Antigen processing by autoreactive B cells promotes determinant spreading  Academic Article
• Antigen processing patterns determine GAD65-specific regulation vs. pathogenesis  Academic Article
• Antigen receptor selection by editing or downregulation of v(d)j recombination  Academic Article
• Antigen recognition by variable lymphocyte receptors  Academic Article
• Antigen selection from an HIV-1 immune antibody library displayed on yeast yields many novel antibodies compared to selection from the same library displayed on phage  Academic Article
• Antigen-induced conformational-changes in antibodies - a problem for structural prediction and design  Academic Article
• Antigen-processing and presentation  Academic Article
• Antigen-specific immunity - th cell-dependent a cell responses  Academic Article
• Antigen-specific memory B cell development  Academic Article
• Antigen-specific regulation of t cell-mediated cytokine production  Academic Article
• Antigenic analysis of the 2nd extra-cellular loop of the human beta-adrenergic receptors  Academic Article
• Antigenic and immunogenic study of membrane-proximal external region-grafted gp120 antigens by a DNA prime-protein boost immunization strategy  Academic Article
• Antigenic and immunologic characterization of an allogeneic colon carcinoma vaccine  Academic Article
• Antigenic expression of human-melanoma cells in serum-free medium  Academic Article
• Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis  Academic Article
• Antigenic mimicry of the hiv envelope by aids-associated pathogens  Academic Article
• Antigenic modulation - a mechanism of viral persistence  Academic Article
• Antigenic modulation induced by monoclonal-antibodies - antibodies to measles-virus hemagglutinin alters expression of other viral polypeptides in infected-cells  Academic Article
• Antigenic peptides  Academic Article
• Antigenic stimulus in human transplantation  Academic Article
• Antigens associated with a human-lung adenocarcinoma defined by monoclonal-antibodies  Academic Article
• Antigens associated with human squamous-cell lung-carcinoma defined by murine monoclonal-antibodies  Academic Article
• Antihistone antibodies in idiopathic and drug-induced lupus recognize distinct intrahistone regions  Academic Article
• Antihypertensive and hypotensive effects of atrial natriuretic factor in men  Academic Article
• Antiidiotype and antihormone receptor antibodies  Academic Article
• Antiidiotypic antibodies against hormone and neurotransmitter receptors  Academic Article
• Antimalarial activity of 10-alkyl/aryl esters and -aminoethylethers of artemisinin  Academic Article
• Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance  Academic Article
• Antimalarials in development in 2014  Academic Article
• Antimitochondrial autoantibodies in primary biliary-cirrhosis recognize cross-reactive epitope(s) on protein-x and dihydrolipoamide acetyltransferase of pyruvate-dehydrogenase complex  Academic Article
• Antimitotic agents of natural origin  Academic Article
• Antimycotic ciclopirox olamine in the diabetic environment promotes angiogenesis and enhances wound healing  Academic Article
• Antimyenteric neuronal antibodies in scleroderma  Academic Article
• Antinuclear antibodies (ANAs): diagnostically specific immune markers and clues toward the understanding of systemic autoimmunity  Academic Article
• Antinuclear antibodies and nuclear antigens in rheumatoid synovial fluids  Academic Article
• Antinuclear antibodies defining autoimmunity pathways  Academic Article
• Antinuclear antibodies in Coombs-positive acquired hemolytic anemia  Academic Article
• Antinuclear antibodies in diagnosis and management  Academic Article
• Antinuclear antibodies in infectious mononucleosis  Academic Article
• Antinuclear antibodies in scleroderma  Academic Article
• Antinuclear antibodies: diagnostic markers and clues to the basis of systemic autoimmunity  Academic Article
• Antinuclear antibodies: diagnostic markers for autoimmune diseases and probes for cell biology  Academic Article
• Antinuclear autoantibodies in prostate cancer: immunity to LEDGF/p75, a survival protein highly expressed in prostate tumors and cleaved during apoptosis  Academic Article
• Antinuclear autoantibodies in women with silicone breast implants  Academic Article
• Antinuclear autoantibodies: probes for defining proteolytic events associated with apoptosis  Academic Article
• Antinuclear, antinucleolar, and anticytoplasmic antibodies in patients with malignant melanoma  Academic Article
• Antinucleolar antibodies in human sera  Academic Article
• Antiparasitic lethality of sulfonamidebenzamides in kinetoplastids  Academic Article
• Antiphospholipid antibodies are directed against epitopes of oxidized phospholipids - recognition of cardiolipin by monoclonal antibodies to epitopes of oxidized low density lipoprotein  Academic Article
• Antiphospholipid antibodies in systemic lupus-erythematosus - clinical and laboratory associations in 111 patients  Academic Article
• Antiplatelet agents in cardiology: the choice of therapy  Academic Article
• Antiplatelet and anticoagulant therapy in the secondary prevention of ischemic heart disease  Academic Article
• Antiplatelet and anticoagulant use after myocardial infarction  Academic Article
• Antiplatelet antibodies in chronic adult immune thrombocytopenic purpura: Assays and epitopes  Academic Article
• Antiplatelet antibodies in chronic immune thrombocytopenia and their role in platelet destruction and defective platelet production  Academic Article
• Antiplatelet medications and their indications in preventing and treating coronary thrombosis  Academic Article
• Antiproliferation activity of a small molecule repressor of liver receptor homolog 1  Academic Article
• Antiproliferative effects of enediynes on aids-derived kaposis-sarcoma cells  Academic Article
• Antiretroviral activity and Vif sensitivity of rhesus macaque APOBEC3 proteins  Academic Article
• Antiretroviral drug resistance mutations in the reverse transcriptase gene of HIV-1 isolates from Northern Indian patients: a follow-up study  Academic Article
• Antiretroviral drug toxicity in relation to pharmacokinetics, metabolic profile and pharmacogenetics  Academic Article
• Antiretroviral treatment of adult HIV infection: 2010 recommendations of the International AIDS Society-USA panel  Academic Article
• Antiretroviral treatment of adult HIV infection: 2012 recommendations of the International Antiviral Society-USA panel  Academic Article
• Antiretroviral treatment of adult HIV infection: 2014 recommendations of the International Antiviral Society-USA Panel  Academic Article
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• Antischistosomal versus antiandrogenic properties of aryl hydantoin Ro 13-3978  Academic Article
• Antisense RNA complementary to 3' coding and noncoding sequences of creatine kinase is a potent inhibitor of translation in vivo  Academic Article
• Antisense RNA complementary to hepatitis B virus specifically inhibits viral replication  Academic Article
• Antisense RNA controls LRP1 sense transcript expression through interaction with a chromatin-associated protein, HMGB2  Academic Article
• Antisense palmitoyl protein thioesterase 1 (PPT1) treatment inhibits PPT1 activity and increases cell death in LA-N-5 neuroblastoma cells  Academic Article
• Antisense treatment of viral-infection  Academic Article
• Antisense-mediated resistance to measles virus infection in hela cells  Academic Article
• Antistress action of a corticotropin-releasing factor antagonist on behavioral reactivity to stressors of varying type and intensity  Academic Article
• Antithrombotic activity of protein S infused without activated protein C in a baboon thrombosis model  Academic Article
• Antithrombotic therapy with intracoronary stenting  Academic Article
• Antitubular basement-membrane antibodies after renal-transplantation  Academic Article
• Antitubular basement-membrane antibodies in methicillin-associated interstitial nephritis  Academic Article
• Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase  Academic Article
• Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic  Academic Article
• Antitumor activity of hu14.18-il2 in patients with relapsed/refractory neuroblastoma: A children's oncology group (cog) phase ii study  Academic Article
• Antitumor effects and mechanisms ofAZD4547on FGFR2-deregulated endometrial cancer cells  Academic Article
• Antitumor efficacy of 26-fluoroepothilone b against human prostate cancer xenografts  Academic Article
• Antiviral activity of a small-molecule inhibitor of arenavirus glycoprotein processing by the cellular site 1 protease  Academic Article
• Antiviral agent blocks breathing of the common cold virus  Academic Article
• Antiviral antibody reacting on the plasma membrane alters measles virus expression inside the cell  Academic Article
• Antiviral antibody responses: the two extremes of a wide spectrum  Academic Article
• Antiviral antibody-responses in patients with renal-disease  Academic Article
• Antiviral cyclic D,L-α-peptides: Targeting a general biochemical pathway in virus infections  Academic Article
• Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication  Academic Article
• Antiviral pressure exerted by hiv-1-specific cytotoxic t lymphocytes (ctls) during primary infection demonstrated by rapid selection of ctl escape virus  Academic Article
• Antiviral stilbene 1,2-diamines prevent initiation of hepatitis C virus RNA replication at the outset of infection  Academic Article
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• Aortocoronary saphenous vein graft disease - pathogenesis, predisposition, and prevention  Academic Article
• Ap-2/eps15 interaction is required for receptor-mediated endocytosis  Academic Article
• Apaf-1 is a transcriptional target for E2F and p53  Academic Article
• Apelin, the natural ligand of the orphan seven-transmembrane receptor APJ, inhibits human immunodeficiency virus type 1 entry  Academic Article
• Apical topography and modulation of ICAM-1 expression on activated endothelium  Academic Article
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• Comment on "Frequency of elevated serum transferrin saturation in elderly subjects"  Academic Article
• Comment on "Mutation rate and genotype variation of Ebola virus from Mali case sequences"  Academic Article
• Comment on "S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function"  Academic Article
• Comment on "Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA"  Academic Article
• Commercial Serology Assays Predict Neutralization Activity against SARS-CoV-2  Academic Article
• Commitment and developmental potential of extrathymic and intrathymic T cell precursors: Plenty to choose from  Academic Article
• Commitment issues: linking positive selection signals and lineage diversification in the thymus  Academic Article
• Common and idiosyncratic patterns of cytokine gene expression by Epstein-Barr virus transformed human B cell lines  Academic Article
• Common cellular and molecular mechanisms in obesity and drug addiction  Academic Article
• Common charge-shift mutation glu65lys in k(+) channel beta(1)-subunit kcnmb1: Pleiotropic consequences for glomerular filtration rate and progressive renal disease  Academic Article
• Common functional genetic variants in catecholamine storage vesicle protein promoter motifs interact to trigger systemic hypertension  Academic Article
• Common genetic mechanisms of blood pressure elevation in two independent rodent models of human essential hypertension  Academic Article
• Common genetic variants in the chromogranin a promoter alter autonomic activity and blood pressure  Academic Article
• Common genetic variation and the control of HIV-1 in humans  Academic Article
• Common genetic variation near the connexin-43 gene is associated with resting heart rate in African Americans: A genome-wide association study of 13,372 participants  Academic Article
• Common immunological determinant between human-immunodeficiency-virus type-1 gp41 and astrocytes  Academic Article
• Common membrane trafficking defects of disease-associated dynamin 2 mutations  Academic Article
• Common susceptibility variants are shared between schizophrenia and psoriasis in the Han Chinese population  Academic Article
• Common tmprss6 mutations and iron, erythrocyte, and pica phenotypes in 48 women with iron deficiency or depletion  Academic Article
• Common tumour p53 mutations in immortalized cells from Hupki mice heterozygous at codon 72  Academic Article
• Common variants at VRK(2) and TCF(4) conferring risk of schizophrenia  Academic Article
• Common variants conferring risk of schizophrenia  Academic Article
• Common variants explain a large fraction of the variability in the liability to psoriasis in a Han Chinese population  Academic Article
• Common variants in kcnn3 are associated with lone atrial fibrillation  Academic Article
• Common variants spanning PLK4 are associated with mitotic-origin aneuploidy in human embryos  Academic Article
• Common vs. Rare allele hypotheses for complex diseases  Academic Article
• Communication in neural circuits: tools, opportunities, and challenges  Academic Article
• Community-hospital administration of intravenous tissue plasminogen-activator in acute myocardial-infarction - improved timing, thrombolytic efficacy and ventricular-function  Academic Article
• Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008  Academic Article
• Comorbidity of select anxiety and affective disorders with alcohol dependence in southwest California Indians  Academic Article
• Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation  Academic Article
• Comparability analysis of protein therapeutics by bottom-up LC-MS with stable isotope-tagged reference standards  Academic Article
• Comparative analysis of human genome assemblies reveals genome-level differences  Academic Article
• Comparative analysis of metastasis variants derived from human prostate carcinoma cells: roles in intravasation of VEGF-mediated angiogenesis and uPA-mediated invasion  Academic Article
• Comparative analysis of the secretory proteome of human adipose stromal vascular fraction cells during adipogenesis  Academic Article
• Comparative analysis of three murine g-protein coupled receptors activated by sphingosine-1-phosphate  Academic Article
• Comparative biomechanical analysis of human and caprine knee articular cartilage  Academic Article
• Comparative characterization of a wild type and transmembrane domain-deleted fatty acid amide hydrolase: Identification of the transmembrane domain as a site for oligomerization  Academic Article
• Comparative characterization of the lactimidomycin and iso-migrastatin biosynthetic machineries revealing unusual features for acyltransferase-less type I polyketide synthases and providing an opportunity to engineer new analogues  Academic Article
• Comparative effects of tetrahydrocannabinol on psychostimulant-induced behaviors  Academic Article
• Comparative epitope mapping of murine monoclonal and human autoantibodies to human pdh-e2, the major mitochondrial autoantigen of primary biliary-cirrhosis  Academic Article
• Comparative gene expression analysis between coronary arteries and internal mammary arteries identifies a role for the tes gene in endothelial cell functions relevant to coronary artery disease  Academic Article
• Comparative immunochemical characterization of products of plasmin and leukocyte protease cleavage of human fibrinogen  Academic Article
• Comparative properties of feline immunodeficiency virus (fiv) and human immunodeficiency virus type 1 (hiv-1) proteinases prepared by total chemical synthesis  Academic Article
• Comparative proteomics reveals a diagnostic signature for pulmonary head-and-neck cancermetastasis  Academic Article
• Comparative reactivities of non-fibrous and fibrous forms of desoxyribonucleoprotein with lupus erythematosus serum  Academic Article
• Comparative studies of the fibrinolytic activity of cultured vascular cells  Academic Article
• Comparative study of antibodies to native and denatured DNA  Academic Article
• Comparative susceptibilities to fidaxomicin (OPT-80) of isolates collected at baseline, recurrence, and failure from patients in two phase III trials of fidaxomicin against Clostridium difficile infection  Academic Article
• Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque  Academic Article
• Comparing antigenicity and immunogenicity of engineered gp120  Academic Article
• Comparing physician-specific two-year patient outcomes after coronary angiography - methodologic issues and results  Academic Article
• Comparison of 2 dose regimens of intravenous tissue plasminogen-activator for acute myocardial-infarction  Academic Article
• Comparison of 24-hour Holter monitoring with 14-day novel adhesive patch electrocardiographic monitoring  Academic Article
• Comparison of 3 coronary stents - clinical and angiographic outcome after elective placement in 134 consecutive patients  Academic Article
• Comparison of EEG sleep measures among depressive subtypes and controls in older individuals  Academic Article
• Comparison of ERCC1/XPF genetic variation, mRNA and protein levels in women with advanced stage ovarian cancer treated with intraperitoneal platinum  Academic Article
• Comparison of aniline hydroxylation by hemoglobin and microsomal cytochrome p450 using stable isotopes  Academic Article
• Comparison of anticoagulant and procoagulant activities of stimulated platelets and platelet-derived microparticles  Academic Article
• Comparison of auditory p300 habituation from active and passive conditions  Academic Article
• Comparison of benefits and complications of hirudin versus heparin for patients with acute coronary syndromes undergoing early percutaneous coronary intervention  Academic Article
• Comparison of bivalirudin versus heparin during percutaneous coronary intervention (the randomized evaluation of pci linking angiomax to reduced clinical events replace -1 trial)  Academic Article
• Comparison of cartilage histopathology assessment systems on human knee joints at all stages of osteoarthritis development  Academic Article
• Comparison of cea-s and cea concentrations in sera and independence of cea-s, nca and blood-group antigens  Academic Article
• Comparison of doppler-derived pressure-gradient to that determined at cardiac-catheterization in adults with aortic-valve stenosis - implications for management  Academic Article
• Comparison of genetic distance measures using human SNP genotype data  Academic Article
• Comparison of glyoxalase I purified from yeast (Saccharomyces cerevisiae) with the enzyme from mammalian sources  Academic Article
• Comparison of histopathologic coronary lesions obtained from directional atherectomy in stable angina versus acute coronary syndromes  Academic Article
• Comparison of human adult stem cells from adipose tissue and bone marrow in the treatment of experimental autoimmune encephalomyelitis  Academic Article
• Comparison of human-monocytes isolated by elutriation and adherence suggests that heterogeneity may reflect a continuum of maturation activation states  Academic Article
• Comparison of in vitro and in vivo approaches to studying brain colonization by breast cancer cells  Academic Article
• Comparison of in vivo body composition using two Lunar dual-energy X-ray absorptiometers  Academic Article
• Comparison of incidence of bleeding and mortality of men versus women with st-elevation myocardial infarction treated with fibrinolysis  Academic Article
• Comparison of injectable molindone and haloperidol followed by oral dosage forms in acutely ill schizophrenics  Academic Article
• Comparison of left-ventricular function and contractile reserve after successful recanalization by thrombolysis versus rescue percutaneous trans-luminal coronary angioplasty for acute myocardial-infarction  Academic Article
• Comparison of lethal and nonlethal transthyretin variants and their relationship to amyloid disease  Academic Article
• Comparison of limulus alpha-macroglobulin with human alpha(2)-macroglobulin: Thiol ester characterization, subunit organization, and conformational change  Academic Article
• Comparison of long-term survival following non-Q-wave creatine kinase elevation after percutaneous coronary intervention in patients discharged on a beta blocker versus those not so treated  Academic Article
• Comparison of long-term usefulness-of clopidogrel therapy after the first percutaneous coronary intervention or coronary artery bypass grafting versus that after the second or repeat intervention  Academic Article
• Comparison of magnetic resonance imaging and transesophageal echocardiography in detection of thrombus in the left atrial appendage  Academic Article
• Comparison of major complication rates with new atherectomy devices for percutaneous coronary intervention in women versus men  Academic Article
• Comparison of mice with accelerated aging caused by distinct mechanisms  Academic Article
• Comparison of miniaturized time-resolved fluorescence resonance energy transfer and enzyme-coupled luciferase high-throughput screening assays to discover inhibitors of Rho-kinase II (ROCK-II)  Academic Article
• Comparison of neutralizing antibody assays for receptor binding and enzyme activity of the enzyme replacement therapeutic Naglazyme (galsulfase)  Academic Article
• Comparison of outcomes of patients with myocardial infarction when living alone versus those not living alone  Academic Article
• Comparison of p300 from a passive tone sequence paradigm and an active discrimination task  Academic Article
• Comparison of p300 from passive and active tasks for auditory and visual stimuli  Academic Article
• Comparison of peak serum c-reactive protein and hydroxybutyrate dehydrogenase levels in patients with acute myocardial infarction treated with alteplase and streptokinase  Academic Article
• Comparison of phenotype between patients with prader-willi syndrome due to deletion 15q and uniparental disomy 15  Academic Article
• Comparison of procedures for testing the equality of survival distributions  Academic Article
• Comparison of protocols for depleting anti-E. coli antibody in immunoblotting of recombinant antigens  Academic Article
• Comparison of reduced alkylated derivatives of some myeloma globulins and Bence-Jones proteins  Academic Article
• Comparison of sibrafiban with aspirin for prevention of cardiovascular events after acute coronary syndromes: A randomised trial  Academic Article
• Comparison of st-segment resolution with combined fibrinolytic and glycoprotein iib/iiia inhibitor therapy versus fibrinolytic alone (data from four clinical trials)  Academic Article
• Comparison of stenting and balloon angioplasty for narrowings in aortocoronary saphenous vein conduits in place for more than five years  Academic Article
• Comparison of the abc/2 estimation technique to computer-assisted volumetric analysis of intraparenchymal and subdural hematomas complicating the gusto-1 trial  Academic Article
• Comparison of the activity of doxorubicin analogs using colony-forming assays and human xenografts  Academic Article
• Comparison of the antitumor efficacies of Her-2/neu DNA vaccines inducing contrasting IgG immunity but comparable CTL activity in mice  Academic Article
• Comparison of the circulating metabolite profile of PF-04991532, a hepatoselective glucokinase activator, across preclinical species and humans: potential implications in metabolites in safety testing assessment  Academic Article
• Comparison of the convergent receptor utilization of a retargeted feline leukemia virus envelope with a naturally-occurring porcine endogenous retrovirus a  Academic Article
• Comparison of the effect of etomidate and desflurane on brain tissue gases and ph during prolonged middle cerebral artery occlusion  Academic Article
• Comparison of the effects of apo(a) kringle IV-10 and plasminogen kringles on the interactions of lipoprotein(a) with regulatory molecules  Academic Article
• Comparison of the lysine binding functions of lipoprotein(a) and plasminogen  Academic Article
• Comparison of the safety and efficacy of emboli prevention devices versus platelet glycoprotein IIb/IIIa inhibition during carotid stenting  Academic Article
• Comparison of the solution conformations of human zn7 -metallothionein-2 and cd7 -metallothionein-2 using nuclear-magnetic-resonance spectroscopy  Academic Article
• Comparison of two platelet glycoprotein IIb/IIIa inhibitors, tirofiban and abciximab, for the prevention of ischemic events with percutaneous coronary revascularization  Academic Article
• Comparisons of Bence-Jones proteins and L polypeptide chains of myeloma globulins after hydrolysis with trypsin  Academic Article
• Comparisons of characteristics and outcomes among women and men with acute myocardial infarction treated with thrombolytic therapy  Academic Article
• Comparisons of several biological and physicochemical properties of human-leukocyte interferons produced by human-leukocytes and by escherichia-coli  Academic Article
• Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis  Academic Article
• Competition between Xenopus satellite-I sequences and Pol-III genes for stable transcription complex-formation  Academic Article
• Competition between bactericidal permeability-increasing protein and lipopolysaccharide-binding protein for lipopolysaccharide binding to monocytes  Academic Article
• Competition between plasminogen and tissue plasminogen activator for cellular binding sites  Academic Article
• Competition of activated protein-C and urokinase for a heparin-dependent inhibitor  Academic Article
• Complement activation by a univalent hapten-antibody complex  Academic Article
• Complement activation in vitro by antiplatelet antibodies in chronic immune thrombocytopenic purpura  Academic Article
• Complement and immunoglobulin deposits in the skin of patients with atopic dermatitis  Academic Article
• Complement and infectious agents - a tale of disguise and deception  Academic Article
• Complement is activated by IgG hexamers assembled at the cell surface  Academic Article
• Complement, viruses, and virus-infected cells  Academic Article
• Complement-activating abilities of defined antinuclear antibodies  Academic Article
• Complement-mediated binding of monocytes to intermediate filaments in vitro  Academic Article
• Complementary clinical benefits of coronary-artery stenting and blockade of platelet glycoprotein IIb/IIIa receptors. Evaluation of Platelet IIb/IIIa Inhibition in Stenting Investigators  Academic Article
• Complementation of a fibre mutant adenovirus by packaging cell lines stably expressing the adenovirus type 5 fibre protein  Academic Article
• Complementation of defective leucine decarboxylation in fibroblasts from a maple syrup urine disease patient by retrovirus-mediated gene transfer  Academic Article
• Complete abolishment of coagulant activity in monomeric disulfide-deficient tissue factor  Academic Article
• Complete amino-acid sequence of a human monocyte chemoattractant, a putative mediator of cellular immune-reactions  Academic Article
• Complete atrioventricular-block complicating inferior wall acute myocardial-infarction treated with reperfusion therapy  Academic Article
• Complete enzymatic deglycosylation of native sex steroid-binding protein (SBP or SHBG) of human and rabbit plasma: effect on the steroid-binding activity  Academic Article
• Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer  Academic Article
• Complete primary structure of porcine tenascin - detection of tenascin transcripts in adult submaxillary-glands  Academic Article
• Complete protein characterization using top-down mass spectrometry and ultraviolet photodissociation  Academic Article
• Complete replication of hepatitis C virus in cell culture  Academic Article
• Complete sequence of the human-tissue factor gene, a highly regulated cellular receptor that initiates the coagulation protease cascade  Academic Article
• Completion of the entire hepatitis C virus life cycle in genetically humanized mice  Academic Article
• Complex formation between urokinase and plasma protein C inhibitor in vitro and in vivo  Academic Article
• Complex genetic organization of junB: multiple blocks of flanking evolutionarily conserved sequence at the murine and human junB loci  Academic Article
• Complex genomic rearrangement in the SOX9 5' region in a patient with Pierre Robin sequence and hypoplastic left scapula  Academic Article
• Complex of a protective antibody with its ebola virus gp peptide epitope: Unusual features of a v lambda(x) light chain  Academic Article
• Complex patterns of genomic admixture within southern Africa  Academic Article
• Complexes of activated protein-C with alpha-1-antitrypsin in normal-pregnancy and in severe preeclampsia  Academic Article
• Complications associated with central venous catheters used for the collection of peripheral blood progenitor cells to support high-dose chemotherapy and autologous stem cell rescue  Academic Article
• Comprehensive analysis and identification of the human STIM1 domains for structural and functional studies  Academic Article
• Comprehensive analysis of structure-activity relationships of a-ketoheterocycles as sn-1-diacylglycerol lipase a inhibitors  Academic Article
• Comprehensive cross-clade neutralization analysis of a panel of anti-human immunodeficiency virus type 1 monoclonal antibodies  Academic Article
• Comprehensive gene- and pathway-based analysis of depressive symptoms in older adults  Academic Article
• Comprehensive linkage and linkage heterogeneity analysis of 4344 sibling pairs affected with hypertension from the family blood pressure program  Academic Article
• Comprehensive mapping of histone modifications at DNA double-strand breaks deciphers repair pathway chromatin signatures  Academic Article
• Comprehensive microrna profiling reveals a unique human embryonic stem cell signature dominated by a single seed sequence  Academic Article
• Comprehensive molecular characterization of human adipocytes reveals a transient brown phenotype  Academic Article
• Comprehensive peptidomimetic libraries targeting protein-protein interactions  Academic Article
• Comprehensive study of sansalvamide a derivatives and their structure-activity relationships against drug-resistant colon cancer cell lines  Academic Article
• Compromised mutant EFEMP1 secretion associated with macular dystrophy remedied by proteostasis network alteration  Academic Article
• Compulsive drug-seeking behavior and relapse. Neuroadaptation, stress, and conditioning factors  Academic Article
• Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells  Academic Article
• Computational design of high-affinity epitope scaffolds by backbone grafting of a linear epitope  Academic Article
• Computational evaluation of protein-small molecule binding  Academic Article
• Computational investigation of RNA CUG repeats responsible for myotonic dystrophy 1  Academic Article
• Computational prediction of atomic structures of helical membrane proteins aided by em maps  Academic Article
• Computational prediction of broadly neutralizing HIV-1 antibody epitopes from neutralization activity data  Academic Article
• Computational screening and design for compounds that disrupt protein-protein interactions  Academic Article
• Computational tools for epitope vaccine design and evaluation  Academic Article
• Computational wear simulation of patellofemoral articular cartilage during in vitro testing  Academic Article
• Computational, pulse-radiolytic, and structural investigations of lysine-136 and its role in the electrostatic triad of human Cu,Zn superoxide dismutase  Academic Article
• Computer vision's potential to improve health care  Academic Article
• Computer-assisted versus manual alignment in THA: a probabilistic approach to range of motion  Academic Article
• Computer-controlled microcirculatory support system for endothelial cell culture and shearing  Academic Article
• Comt polymorphisms and anxiety-related personality traits  Academic Article
• Concentrates of clotting-factor IX  Academic Article
• Concept, design and implementation of a cardiovascular gene-centric 50 k snp array for large-scale genomic association studies  Academic Article
• Concise review: A chemical approach to control cell fate and function  Academic Article
• Concise review: Mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair. Current views  Academic Article
• Concise review: chemical approaches for modulating lineage-specific stem cells and progenitors  Academic Article
• Condensin I and II complexes license full estrogen receptor α-dependent enhancer activation  Academic Article
• Conditional regulation of the human CYP4X1 and CYP4Z1 genes  Academic Article
• Conditioned opioid withdrawal decreases nociceptin/orphanin cortex and olfactory fq levels in the frontal cortex and olfactory tubercle  Academic Article
• Conditions influencing human sperm capacitation and penetration of zona-free hamster ova  Academic Article
• Conformation of prpc on the cell surface as probed by antibodies  Academic Article
• Conformation of the carboxy-terminal region of the a-alpha chain of fibrinogen as elucidated by immunochemical analyses  Academic Article
• Conformational adaptation of human cytochrome p450 2b6 and rabbit cytochrome p450 2b4 revealed upon binding multiple amlodipine molecules  Academic Article
• Conformational and structural modulation of nh2-terminal regions of fibrinogen and fibrin associated with plasmin cleavage  Academic Article
• Conformational changes in fibrinogen elicited by its interaction with platelet membrane glycoprotein GPIIb-IIIa  Academic Article
• Conformational changes in nitric oxide synthases induced by chlorzoxazone and nitroindazoles: crystallographic and computational analyses of inhibitor potency  Academic Article
• Conformational changes in the A1 domain of von Willebrand factor modulating the interaction with platelet glycoprotein Ibα  Academic Article
• Conformational changes induced in the envelope glycoproteins of the human and simian immunodeficiency viruses by soluble receptor binding  Academic Article
• Conformational changes of gp120 in epitopes near the ccr5 binding site are induced by cd4 and a cd4 miniprotein mimetic  Academic Article
• Conformational constraints imposed on a pan-neutralizing hiv-1 antibody epitope result in increased antigenicity but not neutralizing response  Academic Article
• Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding  Academic Article
• Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions  Academic Article
• Conformational flexibility in crystal structures of human 11 β-hydroxysteroid dehydrogenase type I provide insights into glucocorticoid interconversion and enzyme regulation  Academic Article
• Conformational flexibility underlies ubiquitin ligation mediated by the WWP1HECT domain E3 ligase  Academic Article
• Conformational heterogeneity and the affinity of substrate molecular recognition by cytochrome P450cam  Academic Article
• Conformational isomerism can limit antibody catalysis  Academic Article
• Conformational polymorphism of cyclosporine-a  Academic Article
• Conformational states of the full-length glucagon receptor  Academic Article
• Conformational studies of synthetic fragment 1-34 of human parathyroid-hormone by NMR techniques  Academic Article
• Conformational transitions in human translin enable nucleic acid binding  Academic Article
• Conformationally homogeneous heterocyclic pseudotetrapeptides as three-dimensional scaffolds for rational drug design: Receptor-selective somatostatin analogues  Academic Article
• Conformationally restricted analogues designed for selective inhibition of GAR Tfase versus thymidylate synthase or dihydrofolate reductase  Academic Article
• Confronting the issues of patient safety and investigator conflict-of-interest in an international clinical-trial of myocardial reperfusion  Academic Article
• Congenital disease snps target lineage specific structural elements in protein kinases  Academic Article
• Congenital myopathy-causing tropomyosin mutations induce thin filament dysfunction via distinct physiological mechanisms  Academic Article
• Conjugation of functionalized gadolinium metallofullerenes with IL-13 peptides for targeting and imaging glial tumors  Academic Article
• Conjugation of highly reactive aflatoxin B1 exo-8,9-epoxide catalyzed by rat and human glutathione transferases: estimation of kinetic parameters  Academic Article
• Conjugation of styrene oxide by the basic and acidic forms of glutathione transferase in the human fetal liver  Academic Article
• Conjunctive use of platelet glycoprotein IIb/IIIa antagonists and thrombolytic therapy for acute myocardial infarction  Academic Article
• Connectivity and complexity: The relationship between neuroanatomy and brain dynamics  Academic Article
• Connexin mediated cataract prevention in mice  Academic Article
• Connexins in lens development and cataractogenesis  Academic Article
• Conquering Atherosclerotic Cardiovascular Disease-50 Years of Progress  Academic Article
• Consensus generation and variant detection by celera assembler  Academic Article
• Consequences of reocclusion after successful reperfusion therapy in acute myocardial-infarction  Academic Article
• Consequences of secondary or coinfections for immunity  Academic Article
• Consequences of the loss of o-linked glycosylation of meningococcal type iv pilin on piliation and pilus-mediated adhesion  Academic Article
• Conservation of function and regulation within the cdc28/cdc2 protein-kinase family - characterization of the human cdc2hs protein-kinase in saccharomyces-cerevisiae  Academic Article
• Conservation of function between mammalian and plant steroid 5α-reductases  Academic Article
• Conservation of the low-density-lipoprotein receptor-binding domain of apoprotein-b - demonstration by a new monoclonal-antibody, mb47  Academic Article
• Conservation of tissue factor primary sequence among 3 mammalian-species  Academic Article
• Conserved and heterogeneous lipid antigen specificities of CD1d-restricted NKT cell receptors  Academic Article
• Conserved binding mode of human beta(2) adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography  Academic Article
• Conserved changes in envelope function during human immunodeficiency virus type 1 coreceptor switching  Academic Article
• Conserved chromosomal location and genomic structure of human and mouse fatty-acid amide hydrolase genes and evaluation of clasper as a candidate neurological mutation  Academic Article
• Conserved features of intermediates in amyloid assembly determine their benign or toxic states  Academic Article
• Conserved functions of membrane active gtpases in coated vesicle formation  Academic Article
• Conserved linkage between the puffer fish (Fugu rubripes) and human genes for platelet-derived growth factor receptor and macrophage colony-stimulating factor receptor  Academic Article
• Conserved primary sequences of the DNA terminal proteins of 5 different human adenovirus groups  Academic Article
• Conserved receptor-binding domains of Lake Victoria marburgvirus and Zaire ebolavirus bind a common receptor  Academic Article
• Conserved regulation of the lymphocyte-specific expression of lck in the Fugu and mammals  Academic Article
• Conserved residues in lassa fever virus Z protein modulate viral infectivity at the level of the ribonucleoprotein  Academic Article
• Conserved sequence-specific lincRNA-steroid receptor interactions drive transcriptional repression and direct cell fate  Academic Article
• Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes  Academic Article
• Conserved structural motifs governing the stoichiometric repair of alkylated DNA by o-6-alkylguanine-DNA alkyltransferase  Academic Article
• Conserved synteny between the Fugu and human PTEN locus and the evolutionary conservation of vertebrate PTEN function  Academic Article
• Conserved synteny between the chicken Z sex chromosome and human chromosome 9 includes the male regulatory gene DMRT1: a comparative (re)view on avian sex determination  Academic Article
• Considerable interindividual variation in the pharmacokinetics of tolperisone hcl  Academic Article
• Considerations in the medical management of pregnancy in transplant recipients  Academic Article
• Considerations on temperature, longevity and aging  Academic Article
• Consistency of T2 gene signatures in severe asthma key to effective treatments or merely the tip of the iceberg?  Academic Article
• Constitutional aneuploidy in the normal human brain  Academic Article
• Constitutional delay in growth and puberty (CDGP) is associated with hypoleptinaemia  Academic Article
• Constitutive activation of integrin alpha 4 beta 1 defines a unique stage of human thymocyte development  Academic Article
• Constitutive activity of the melanocortin-4 receptor is maintained by its n-terminal domain and plays a role in energy homeostasis in humans  Academic Article
• Constitutive activity of the tumor necrosis factor promoter is canceled by the 3' untranslated region in nonmacrophage cell lines; a trans-dominant factor overcomes this suppressive effect  Academic Article
• Constitutive and Regulated Shedding of Soluble FGF Receptors Releases Biologically Active Inhibitors of FGF-2  Academic Article
• Constitutive c-myc expression in an il-3-dependent myeloid cell-line suppresses cell-cycle arrest and accelerates apoptosis  Academic Article
• Constitutive expression of murine decay-accelerating factor 1 is controlled by the transcription factor sp1  Academic Article
• Constitutive intra-articular expression of human IL-1 beta following gene transfer to rabbit synovium produces all major pathologies of human rheumatoid arthritis  Academic Article
• Constitutive nadph oxidase 4 activity resides in the composition of the b-loop and the penultimate c terminus  Academic Article
• Constitutive, long-term production of human interferons by hamster-cells containing multiple copies of a cloned interferon gene  Academic Article
• Constitutively active rheb induces oncogenic transformation  Academic Article
• Constructing de novo H2O2 signaling via induced protein proximity  Academic Article
• Constructing molecular complexity and diversity: Total synthesis of natural products of biological and medicinal importance  Academic Article
• Construction and characterization of retroviral vectors expressing biologically active human interleukin-12  Academic Article
• Construction of retroviral vectors with improved safety, gene expression, and versatility  Academic Article
• Construction, affinity maturation, and biological characterization of an anti-tumor-associated glycoprotein-72 humanized antibody  Academic Article
• Consumer perceptions of direct-to-consumer personalized genomic risk assessments  Academic Article
• Contact inhibition against senescence  Academic Article
• Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals  Academic Article
• Contemporary North American influenza H7 viruses possess human receptor specificity: Implications for virus transmissibility  Academic Article
• Contemporary clinical-trials of restenosis  Academic Article
• Contemporary human genetic strategies in aging research  Academic Article
• Contemporary reperfusion therapy for cardiogenic-shock - the gusto-i trial experience  Academic Article
• Contemporary, yeast-based approaches to understanding human genetic variation  Academic Article
• Contenders in fasl/tnf death signaling  Academic Article
• Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies  Academic Article
• Context-dependent effects of asparagine glycosylation on Pin WW folding kinetics and thermodynamics  Academic Article
• Context-dependent proangiogenic function of bone morphogenetic protein signaling is mediated by disabled homolog 2  Academic Article
• Contextual control of skin immunity and inflammation by Corynebacterium  Academic Article
• Continuing education course #2: Current understanding of hemostasis  Academic Article
• Continuous 12-lead st-segment recovery analysis in the tami 7 study - performance of a noninvasive method for real-time detection of failed myocardial reperfusion  Academic Article
• Continuous directed evolution of DNA-binding proteins to improve TALEN specificity  Academic Article
• Continuous directed evolution of proteins with improved soluble expression  Academic Article
• Continuous in vitro evolution of a ribozyme ligase: a model experiment for the evolution of a biomolecule  Academic Article
• Continuous production of carcinoembryonic antigen in hollow fiber cell-culture units - brief communication  Academic Article
• Contrasting IgG structures reveal extreme asymmetry and flexibility  Academic Article
• Contribution of 20 single nucleotide polymorphisms of 13 genes to dyslipidemia associated with antiretroviral therapy  Academic Article
• Contribution of LCMV towards deciphering biology of quasispecies in vivo  Academic Article
• Contribution of amino acid residue 208 in the hydrophobic binding site to the catalytic mechanism of human glutathione transferase A1-1  Academic Article
• Contribution of charged amino acids in the CDR2 region of CD4 to HIV-1 gp120 binding  Academic Article
• Contribution of distinct adhesive interactions to platelet aggregation in flowing blood  Academic Article
• Contribution of five amino acid residues in the glutathione-binding site to the function of human glutathione transferase P1-1  Academic Article
• Contribution of genetic background, traditional risk factors, and HIV-related factors to coronary artery disease events in HIV-positive persons  Academic Article
• Contribution of genome-wide significant single-nucleotide polymorphisms and antiretroviral therapy to dyslipidemia in HIV-infected individuals: a longitudinal study  Academic Article
• Contribution of glutamatergic signaling to nitrosative stress-induced protein misfolding in normal brain aging and neurodegenerative diseases  Academic Article
• Contribution of glutathione transferase M3-3 to 1,3-bis(2-chloroethyl)-1-nitrosourea resistance in a human non-small cell lung cancer cell line  Academic Article
• Contribution of glycine 146 to a conserved folding module affecting stability and refolding of human glutathione transferase P1-1  Academic Article
• Contribution of histidine-rich glycoprotein in clearance of immune complexes and apoptotic cells: Implications for ameliorating autoimmune diseases  Academic Article
• Contribution of human manganese superoxide dismutase tyrosine 34 to structure and catalysis  Academic Article
• Contribution of leptin receptor N-linked glycans to leptin binding  Academic Article
• Contribution of mutations in known Mendelian glaucoma genes to advanced early-onset primary open-angle glaucoma  Academic Article
• Contribution of platelets to tumour metastasis  Academic Article
• Contribution of proteoglycans to human immunodeficiency virus type 1 brain invasion  Academic Article
• Contribution of receptor editing to the antibody repertoire  Academic Article
• Contributions of ethnicity to differential item functioning of cannabis abuse and dependence symptoms  Academic Article
• Contributions of human-platelets to the proteolytic activation of blood-coagulation factor-XII and factor-XI  Academic Article
• Contributions of individual nucleotides to tertiary binding of substrate by a Pneumocystis carinii group I intron  Academic Article
• Contributions of ionic interactions and protein dynamics to cytochrome P450 2D6 (CYP2D6) substrate and inhibitor binding  Academic Article
• Control of craving by the prefrontal cortex  Academic Article
• Control of developmental regulator's by Polycomb in human embryonic stem cells  Academic Article
• Control of egf receptor signaling by clathrin-mediated endocytosis  Academic Article
• Control of interneuron dendritic growth through NRG1/erbB4-mediated kalirin-7 disinhibition  Academic Article
• Control of lipopolysaccharide (lps) binding and lps-induced tumor-necrosis-factor secretion in human peripheral-blood monocytes  Academic Article
• Control of lipopolysaccharide high-density lipoprotein interactions by an acute-phase reactant in human-serum  Academic Article
• Control of rna processing by a large non-coding rna over-expressed in carcinomas  Academic Article
• Control of the g(1)/s transition  Academic Article
• Control of translocations between highly diverged genes by Sgs1, the Saccharomyces cerevisiae homolog of the Bloom's syndrome protein  Academic Article
• Controlled transcription of a human alpha-interferon gene introduced into mouse l-cells  Academic Article
• Controlling activation of the RNA-dependent protein kinase by siRNAs using site-specific chemical modification  Academic Article
• Controlling mammalian gene expression by allosteric hepatitis delta virus ribozymes  Academic Article
• Controlling mutation: Intervening in evolution as a therapeutic strategy  Academic Article
• Controlling transcription with noncoding RNAs in mammalian cells  Academic Article
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• Coronary angioplasty in myocardial infarction  Academic Article
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• Creation of a large-scale genetic data bank for cardiovascular association studies  Academic Article
• Creep of trabecular bone from the human proximal tibia  Academic Article
• Creutzfeldt-Jakob disease  Academic Article
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• Critical evaluation of bispecific antibodies as targetins agents for boron neutron capture therapy of brain tumors  Academic Article
• Critical role for conversion of Glu-plasminogen to Lys-plasminogen for optimal stimulation of plasminogen activation on cell surfaces  Academic Article
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• Cross-neutralization of human and palm civet severe acute respiratory syndrome coronaviruses by antibodies targeting the receptor-binding domain of spike protein  Academic Article
• Cross-neutralizing activity of human anti-V3 monoclonal antibodies derived from non-B clade HIV-1 infected individuals  Academic Article
• Cross-reactive Antibody Response between SARS-CoV-2 and SARS-CoV Infections 
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• Cross-reactive serum and memory B-cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection  Academic Article
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• Cross-talk between intraepithelial gamma delta T cells and epithelial cells  Academic Article
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• Cross-talk between snurportin1 subdomains  Academic Article
• Cross-talk of integrin alpha 3 beta 1 and tissue factor in cell migration  Academic Article
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• Cryo-EM structure of human GPR158 receptor coupled to the RGS7-G beta 5 signaling complex  Academic Article
• Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating  Academic Article
• Cryo-EM structures and atomic model of the HIV-1 strand transfer complex intasome  Academic Article
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• Cryopreservation of human mucosal tissues  Academic Article
• Cryopreservation of neurospheres derived from human glioblastoma multiforme  Academic Article
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• Cryptochromes: bringing the blues to circadian rhythms  Academic Article
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• Crystal structure of a soluble cleaved HIV-1 envelope trimer  Academic Article
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• Crystal structure of human vacuolar protein sorting protein 29 reveals a phosphodiesterase/nuclease-like fold and two protein-protein interaction sites  Academic Article
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• Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain  Academic Article
• Crystal structure of the C-terminal domain of mouse TLR9  Academic Article
• Crystal structure of the Frizzled 4 receptor in a ligand-free state  Academic Article
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• Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran  Academic Article
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• Cyclophilin and NS5A inhibitors, but not other anti-hepatitis C virus (HCV) agents, preclude HCV-mediated formation of double-membrane-vesicle viral factories  Academic Article
• Cyclophilin inhibitors  Academic Article
• Cyclophilin inhibitors for the treatment of HCV infection  Academic Article
• Cyclophilin inhibitors: A novel class of promising host-targeting anti-HCV agents  Academic Article
• Cyclophilin inhibitors: An emerging class of therapeutics for the treatment of chronic hepatitis C infection  Academic Article
• Cyclophilin involvement in the replication of hepatitis C virus and other viruses  Academic Article
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• Cysteine cathepsins in the secretory vesicle produce active peptides: cathepsin L generates peptide neurotransmitters and cathepsin B produces beta-amyloid of Alzheimer's disease  Academic Article
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• Cysteine modifiers suggest an allosteric inhibitory site on the CAL PDZ domain  Academic Article
• Cysteine regulation of protein function - as exemplified by NMDA-receptor modulation  Academic Article
• Cysteine residues are not essential for the catalytic activity of human class Mu glutathione transferase M1a-1a  Academic Article
• Cysteine-mediated redox signaling: chemistry, biology, and tools for discovery  Academic Article
• Cysteine-specific chemical proteomics: from target identification to drug discovery  Academic Article
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• Cystic fibrosis therapy: a community ecology perspective  Academic Article
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• Cytokine signals through PI-3 kinase pathway modulate Th17 cytokine production by CCR6+ human memory T cells  Academic Article
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• Cytokine-induced viral purging - role in viral pathogenesis  Academic Article
• Cytokine-mediated control of viral infections  Academic Article
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• Cytokine-stimulated, but not HIV-infected, human monocyte-derived macrophages produce neurotoxic levels of L-cysteine  Academic Article
• Cytokines and cancer cachexia  Academic Article
• Cytokines and t cell homeostasis  Academic Article
• Cytokines and t-cell homeostasis  Academic Article
• Cytokines in cartilage injury and repair  Academic Article
• Cytokines in neuronal cell types  Academic Article
• Cytokines in symptomatic asthma airways  Academic Article
• Cytomegalovirus activates interferon immediate-early response gene expression and an interferon regulatory factor 3-containing interferon-stimulated response element-binding complex  Academic Article
• Cytomegalovirus infects human-lymphocytes and monocytes - virus expression is restricted to immediate-early gene-products  Academic Article
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• Cytoprotective protein C pathways and implications for stroke and neurological disorders  Academic Article
• Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes  Academic Article
• Cytoprotective-selective activated protein C attenuates pseudomonas aeruginosa-induced lung injury in mice  Academic Article
• Cytoprotective-selective activated protein C therapy for ischaemic stroke  Academic Article
• Cytoskeletal components of an invasion machine: the apical complex of Toxoplasma gondii  Academic Article
• Cytosol- and clathrin-dependent stimulation of endocytosis in vitro by purified adaptors  Academic Article
• Cytotoxic T cells and viral hepatitis  Academic Article
• Cytotoxic T lymphocyte response to hepatitis C virus-derived peptides containing the HLA A2.1 binding motif  Academic Article
• Cytotoxic T lymphocyte responsiveness after resolution of chronic hepatitis B virus infection  Academic Article
• Cytotoxic T lymphocytes recognize an HLA-A2-restricted epitope within the hepatitis B virus nucleocapsid antigen  Academic Article
• Cytotoxic T-lymphocyte response to a wild-type hepatitis-B virus epitope in patients chronically infected by variant viruses carrying substitutions within the epitope  Academic Article
• Cytotoxic lymphocytes generated in vivo with acute measles virus infection  Academic Article
• Cytotoxicity of a Ti(IV) compound is independent of serum proteins  Academic Article
• Cytotoxicity of quantum dots used for in vitro cellular labeling: role of QD surface ligand, delivery modality, cell type, and direct comparison to organic fluorophores  Academic Article
• D-4 dopamine receptor high-resolution structures enable the discovery of selective agonists  Academic Article
• D-Ornithine coopts pyrrolysine biosynthesis to make and insert pyrroline-carboxy-lysine  Academic Article
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• DAF-12-dependent rescue of dauer formation in Caenorhabditis elegans by (25S)-cholestenoic acid  Academic Article
• DAMB, a novel dopamine receptor expressed specifically in Drosophila mushroom bodies  Academic Article
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• DCAF11 Supports Targeted Protein Degradation by Electrophilic Proteolysis-Targeting Chimeras  Academic Article
• DCAF4, a novel gene associated with leucocyte telomere length  Academic Article
• DDA3 recruits microtubule depolymerase Kif2a to spindle poles and controls spindle dynamics and mitotic chromosome movement  Academic Article
• DDAVP enhances platelet adherence and platelet aggregate growth on human artery subendothelium  Academic Article
• DDAVP in haemophilia  Academic Article
• DDX1 is an RNA-dependent ATPase involved in HIV-1 Rev function and virus replication  Academic Article
• DEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A  Academic Article
• DICER- and AGO3-dependent generation of retinoic acid-induced DR2 Alu RNAs regulates human stem cell proliferation  Academic Article
• DISC1 regulates trafficking and processing of APP and Aβ generation  Academic Article
• DISCovery in psychiatric genetics  Academic Article
• DIx5 homeodomain:DNA complex: structure, binding and effect of mutations related to split hand and foot malformation syndrome  Academic Article
• DNA arrays: applications and implications for circadian biology  Academic Article
• DNA binding alters coactivator interaction surfaces of the intact VDR-RXR complex  Academic Article
• DNA binding and nucleotide flipping by the human DNA repair protein agt  Academic Article
• DNA binding domain in the replication checkpoint protein Mrc1 of Schizosaccharomyces pombe  Academic Article
• DNA binding fluorescent proteins for the direct visualization of large DNA molecules  Academic Article
• DNA binding, nucleotide flipping, and the helix-turn-helix motif in base repair by o-6-alkylguanine-DNA alkyltransferase and its implications for cancer chemotherapy  Academic Article
• DNA binding-dependent glucocorticoid receptor activity promotes adipogenesis via Kruppel-like factor 15 gene expression  Academic Article
• DNA damage recognition and repair pathway coordination revealed by the structural biochemistry of DNA repair enzymes  Academic Article
• DNA damage triggers Golgi dispersal via DNA-PK and GOLPH3  Academic Article
• DNA display of PNA-tagged ligands: A versatile strategy to screen libraries and control geometry of multidentate ligands  Academic Article
• DNA double-strand break repair pathway choice Is directed by distinct MRE11 nuclease activities  Academic Article
• DNA immunization: Mechanistic studies  Academic Article
• DNA loops induced by cooperative binding of transcriptional activator proteins and preinitiation complexes  Academic Article
• DNA methylation analysis of human myoblasts during in vitro myogenic differentiation: de novo methylation of promoters of muscle-related genes and its involvement in transcriptional down-regulation  Academic Article
• DNA methylation and chromatin structure regulate T cell perforin gene expression  Academic Article
• DNA methylation fingerprint of neuroblastoma reveals new biological and clinical insights  Academic Article
• DNA methylation in embryonic stem cells  Academic Article
• DNA polymerase activity assay using near-infrared fluorescent labeled DNA visualized by acrylamide gel electrophoresis  Academic Article
• DNA polymerase activity at the single-molecule level  Academic Article
• DNA repair and global sumoylation are regulated by distinct Ubc9 noncovalent complexes  Academic Article
• DNA repair is crucial for maintaining hematopoietic stem cell function  Academic Article
• DNA repair mechanisms for the recognition and removal of damaged DNA bases  Academic Article
• DNA replication checkpoint  Academic Article
• DNA replication checkpoint control  Academic Article
• DNA sequence-specific polyamides alleviate transcription inhibition associated with long GAA.TTC repeats in Friedreich's ataxia  Academic Article
• DNA vaccination to treat autoimmune diabetes  Academic Article
• DNA-based vaccines activate innate and adaptive antitumor immunity by engaging the nkg2d receptor  Academic Article
• DNA-binding property of Sm nuclear antigen  Academic Article
• DNA-binding proteins in human-serum  Academic Article
• DNA-bound structures and mutants reveal abasic DNA binding by ape1 DNA repair and coordination  Academic Article
• DNA-dependent protein kinase inhibitors as drug candidates for the treatment of cancer  Academic Article
• DNA-encoded library versus RNA-encoded library selection enables design of an oncogenic noncoding RNA inhibitor  Academic Article
• DNA-repair proteins  Academic Article
• DNase I inhibits a late phase of reactive oxygen species production in neutrophils  Academic Article
• DOLORS: versatile strategy for internal labeling and domain localization in electron microscopy  Academic Article
• DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis  Academic Article
• DUB-resistant ubiquitin to survey ubiquitination switches in mammalian cells  Academic Article
• DUBs, the regulation of cell identity and disease  Academic Article
• DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes  Academic Article
• Daily eating patterns and their impact on health and disease  Academic Article
• Damage to the bases in DNA induced by stimulated human neutrophils  Academic Article
• Daring to learn from humanized mice  Academic Article
• Database searching using mass spectrometry data  Academic Article
• Dax1 mutations map to putative structural domains in a deduced three-dimensional model  Academic Article
• Dbf4 is direct downstream target of ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related (ATR) protein to regulate intra-S-phase checkpoint  Academic Article
• De novo KCNB1 mutations in epileptic encephalopathy  Academic Article
• De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures  Academic Article
• De novo designed transmembrane peptides activating the alpha(5)beta(1) integrin  Academic Article
• De novo identification of VRC01 class HIV-1-neutralizing antibodies by next-generation sequencing of B-cell transcripts  Academic Article
• De novo identification of tumor-specific internalizing human antibody-receptor pairs by phage-display methods  Academic Article
• De novo kidney transplantation without use of calcineurin inhibitors preserves renal structure and function at two years  Academic Article
• De novo-designed enzymes as small-molecule-regulated fluorescence imaging tags and fluorescent reporters  Academic Article
• De-novo humoral immune responses to cancer-associated autoantigens during transition from chronic liver disease to hepatocellular carcinoma  Academic Article
• Deadly Portland Cement: The Triad of Pulmonary, Dermatologic and Hematological Manifestations  Academic Article
• Death and nonfatal reinfarction within the first 24 hours after presentation with an acute coronary syndrome: Experience from gusto-iib  Academic Article
• Death following creatine kinase-mb elevation after coronary intervention - identification of an early risk period: Importance of creatine kinase-mb level, completeness of revascularization, ventricular function, and probable benefit of statin therapy  Academic Article
• Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function  Academic Article
• Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis  Academic Article
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• Deciphering the chromatin landscape induced around DNA double strand breaks  Academic Article
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• Decoding arenavirus pathogenesis: Essential roles for alpha-dystroglycan-virus interactions and the immune response  Academic Article
• Decoding human cytomegalovirus  Academic Article
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• Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression, and apoptosis in mice lacking fatty acid amide hydrolase  Academic Article
• Decreased cure and increased recurrence rates for Clostridium difficile infection caused by the epidemic C. difficile BI strain  Academic Article
• Decreased expression of NMDA receptor-associated proteins in frontal cortex of elderly patients with schizophrenia  Academic Article
• Decreased frequency of rearrangement due to the synergistic effect of nucleotide changes in the heptamer and nonamer of the recombination signal sequence of the V kappa gene A2B, which is associated with increased susceptibility of navajos to haemophilus influenzae type B disease  Academic Article
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• Decreased perihematomal edema in thrombolysis-related intracerebral hemorrhage compared with spontaneous intracerebral hemorrhage  Academic Article
• Decreased plasma levels of protein S in well-controlled type I diabetes mellitus  Academic Article
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• Decreased production of nitric oxide by human neutrophils during septic multiple organ dysfunction syndrome. Comparison with endotoxin and cytokine effects on normal cells  Academic Article
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• Deficiency of lrp8 in mice is associated with altered platelet function and prolonged time for in vivo thrombosis  Academic Article
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• Defining the role of oxygen tension in human neural progenitor fate  Academic Article
• Definition of a minimal optimal cytotoxic T-cell epitope within the hepatitis B virus nucleocapsid protein  Academic Article
• Definition of the sites of interaction between the protein tyrosine phosphatase SHP-1 and CD22  Academic Article
• Degeneracy and complexity in biological systems  Academic Article
• Degenerate immunogenicity of an HLA-A2-restricted hepatitis B virus nucleocapsid cytotoxic T-lymphocyte epitope that is also presented by HLA-B51  Academic Article
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• Degradation, foraging, and depletion of mucus sialoglycans by the vagina-adapted Actinobacterium Gardnerella vaginalis  Academic Article
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• Deletion mutants of human interleukin 1β with significantly reduced agonist properties: Search for the agonist/antagonist switch in ligands to the interleukin 1 receptors  Academic Article
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• Deletion of nef slows but does not prevent CD4-positive T-cell depletion in human immunodeficiency virus type 1-infected human-PBL-SCID mice  Academic Article
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• Deletions within the 5 ' utr of coxsackievirus b3: Consequences for virus translation and replication  Academic Article
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• Delineation of the peptide binding site of the human galanin receptor  Academic Article
• Delivering quantum dot-peptide bioconjugates to the cellular cytosol: escaping from the endolysosomal system  Academic Article
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• Delivery of proteases in aqueous two-phase systems enables direct purification of stem cell colonies from feeder cell co-cultures for differentiation into functional cardiomyocytes  Academic Article
• Delta-9,11 modification of glucocorticoids dissociates nuclear factor-κB inhibitory efficacy from glucocorticoid response element-associated side effects  Academic Article
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• Demonstration of functional similarity of proposed biosimilar ABP 501 to adalimumab  Academic Article
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• Dental caries pathogenicity: A genomic and metagenomic perspective  Academic Article
• Dentin conditioning codetermines cell fate in regenerative endodontics  Academic Article
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• Deoxyribonucleic acid antibody: a method to detect its primary interaction with deoxyribonucleic acid  Academic Article
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• Depletion of calcium from the lumen of endoplasmic-reticulum reversibly inhibits passive diffusion and signal-mediated transport into the nucleus  Academic Article
• Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress  Academic Article
• Depletion of neutrophils blocks the recruitment of antigen-nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus-specific cytotoxic T lymphocytes  Academic Article
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• Depression symptoms associated with cannabis dependence in an adolescent American Indian community sample  Academic Article
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• Deregulated cyclin e induces chromosome instability  Academic Article
• Deregulation of cyclin e in human cells interferes with prereplication complex assembly  Academic Article
• Deregulation of the c-myc and n-myc genes in transformed cells  Academic Article
• Derivation and characterization of a UCP1 reporter human ES cell line  Academic Article
• Derivation and characterization of a simian immunodeficiency virus SIVmac239 variant with tropism for CXCR4  Academic Article
• Derivation and validation of a simple clinical bedside score (ATLAS) for Clostridium difficile infection which predicts response to therapy  Academic Article
• Derivation of HLA-A11/Kb transgenic mice: functional CTL repertoire and recognition of human A11-restricted CTL epitopes  Academic Article
• Derivation of a retinoid x receptor scaffold from peroxisome proliferator-activated receptor gamma ligand 1-di(1h-indol-3-yl)methyl-4-trifluoromethylbenzene  Academic Article
• Derivatives of (3S)-N-(biphenyl-2-ylmethyl)pyrrolidin-3-amine as selective noradrenaline reuptake inhibitors: Reducing P-gp mediated efflux by modulation of H-bond acceptor capacity  Academic Article
• Derivatives of 4-amino-3,6-disulfonato-1,8-naphthalimide inhibit reverse-transcriptase and suppress human and feline immunodeficiency virus expression in cultured-cells  Academic Article
• Deriving four functional anti-HIV siRNAs from a single Pol III-generated transcript comprising two adjacent long hairpin RNA precursors  Academic Article
• Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease  Academic Article
• Dermatan sulfate and LMW heparin enhance the anticoagulant action of activated protein C  Academic Article
• Descending command systems for the initiation of locomotion in mammals  Academic Article
• Description of the data from the collaborative study on the genetics of alcoholism (coga) and single-nucleotide polymorphism genotyping for genetic analysis workshop 14  Academic Article
• Desensitization and endocytosis mechanisms of ghrelin-activated growth hormone secretagogue receptor 1a  Academic Article
• Desensitization of G protein-coupled receptors and neuronal functions  Academic Article
• Desensitization of the beta-adrenergic response in human brown adipocytes  Academic Article
• Desflurane increases brain tissue oxygenation and ph  Academic Article
• Design and characterization of a DNA-encoded, voltage-sensitive fluorescent protein  Academic Article
• Design and characterization of an active site selective caspase-3 transnitrosating agent  Academic Article
• Design and characterization of epitope-scaffold immunogens that present the motavizumab epitope from respiratory syncytial virus  Academic Article
• Design and characterization of stabilized derivatives of human cd4d12 and cd4d1  Academic Article
• Design and discovery of N-(2-Methyl-5 '-morpholino-6 '-((tetrahydro-2H-pyran-4-yl)oxy)- 3,3 '-bipyridin -5-yl)-3-(trifluoromethyl)benzamide (RAF709): a potent, selective, and efficacious RAF inhibitor targeting RAS mutant cancers  Academic Article
• Design and evaluation of novel 8-oxo-pyridopyrimidine Jak1/2 inhibitors  Academic Article
• Design and evolution of new catalytic activity with an existing protein scaffold  Academic Article
• Design and simulation of a neutron source based on an electron linear accelerator for bnct of skin melanoma  Academic Article
• Design and structure of an engineered disulfide-stabilized influenza virus hemagglutinin trimer  Academic Article
• Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens  Academic Article
• Design and synthesis of 2-amino-isoxazolopyridines as Polo-like kinase inhibitors  Academic Article
• Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors  Academic Article
• Design and synthesis of 2-substituted-5-(4-trifluoromethylphenyl-sulphonamido)benzoxazole derivatives as human GST P1-1 inhibitors  Academic Article
• Design and synthesis of AX4697, a bisindolylmaleimide exo-affinity probe that labels protein kinase C alpha and beta  Academic Article
• Design and synthesis of Hsp90 inhibitors: Exploring the SAR of Sansalvamide A derivatives  Academic Article
• Design and synthesis of a biaryl series as inhibitors for the bromodomains of CBP/P300  Academic Article
• Design and synthesis of a cell-permeable synthetic transcription factor mimic  Academic Article
• Design and synthesis of alpha-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis  Academic Article
• Design and synthesis of conformationally constrained 3-(n-alkylamino)propylphosphonic acids as potent agonists of sphingosine-1-phosphate (s1p) receptors  Academic Article
• Design and synthesis of highly potent and isoform selective JNK3 inhibitors: SAR studies on aminopyrazole derivatives  Academic Article
• Design and synthesis of novel hybrid benzamide-peptide histone deacetylase inhibitors  Academic Article
• Design and synthesis of potent, selective, and orally bioavailable tetrasubstituted imidazole inhibitors of p38 mitogen-activated protein kinase  Academic Article
• Design and synthesis of reboxetine analogs morpholine derivatives as selective norepinephrine reuptake inhibitors  Academic Article
• Design of RNAi hairpins for mutation-specific silencing of ataxin-7 and correction of a SCA7 phenotype  Academic Article
• Design of a Janus kinase 3 (JAK3) specific inhibitor 1-(2s,5R)-5-((7H-pyrrolo 2,3-d pyrimidin-4-yl)amino)-2-methylpiperidin-1 -y1)prop-2-en-1-one (PF-06651600) allowing for the interrogation of JAK3 signaling in humans  Academic Article
• Design of a bioactive small molecule that targets the myotonic dystrophy type 1 RNA via an RNA motif-ligand database and chemical similarity searching  Academic Article
• Design of a monomeric human glutathione transferase gstp1, a structurally stable but catalytically inactive protein  Academic Article
• Design of a potent CD1d-binding NKT cell ligand as a vaccine adjuvant  Academic Article
• Design of immunogens to elicit broadly neutralizing antibodies against HIV targeting the CD4 binding site  Academic Article
• Design of multivalent galactosyl carborane as a targeting specific agent for potential application to boron neutron capture therapy  Academic Article
• Design of peptide imaging agents for whole-body and intraoperative molecular imaging  Academic Article
• Design of polydactyl zinc-finger proteins for unique addressing within complex genomes  Academic Article
• Design of potent and proteolytically stable oxyntomodulin analogs  Academic Article
• Design of potent and selective 2-aminobenzimidazole-based p38 alpha MAP kinase inhibitors with excellent in vivo efficacy  Academic Article
• Design of specific mechanism-based inactivators of hepatic and adrenal microsomal cytochromes-P-450 responsible for progesterone 21-hydroxylation  Academic Article
• Design of the blockade of the glycoprotein iib/iiia receptor to avoid vascular occlusion (bravo) trial  Academic Article
• Design of two chimaeric human-rat class alpha glutathione transferases for probing the contribution of C-terminal segments of protein structure to the catalytic properties  Academic Article
• Design, synthesis and SAR analysis of novel potent and selective small molecule antagonists of NPBWR1 (GPR7)  Academic Article
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• Design, synthesis and biological evaluation of artemisinin derivatives containing fluorine atoms as anticancer agents  Academic Article
• Design, synthesis and biological evaluation of nonpeptide integrin antagonists  Academic Article
• Design, synthesis and biological evaluation of novel 4-phenylisoquinolinone BET bromodomain inhibitors  Academic Article
• Design, synthesis and biological evaluation of novel pyrenyl derivatives as anticancer agents  Academic Article
• Design, synthesis and biological-activity of protaxols  Academic Article
• Design, synthesis and evaluation of 2,5-diketopiperazines as inhibitors of the MDM2-p53 interaction  Academic Article
• Design, synthesis and evaluation of a PLG tripeptidomimetic based on a pyridine scaffold  Academic Article
• Design, synthesis and structure-activity relationships of novel biarylamine-based Met kinase inhibitors  Academic Article
• Design, synthesis, and activity of HDAC inhibitors with a N-formyl hydroxylamine head group  Academic Article
• Design, synthesis, and biological activities of closantel analogues: structural promiscuity and its impact on Onchocerca volvulus  Academic Article
• Design, synthesis, and biological activity of substrate competitive SMYD2 inhibitors  Academic Article
• Design, synthesis, and biological evaluation of 10-methanesulfonyl-DDACTHF, 10-methanesulfonyl-5-DACTHF, and 10-methylthio-DDACTHF as potent inhibitors of GAR Tfase and the de novo purine biosynthetic pathway  Academic Article
• Design, synthesis, and biological evaluation of 3-[4-(2-hydroxyethyl)piperazin-1-yl]-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one, a potent, orally active, brain penetrant inhibitor of phosphodiesterase 5 (PDE5)  Academic Article
• Design, synthesis, and biological evaluation of a biyouyanagin compound library  Academic Article
• Design, synthesis, and biological evaluation of novel aminopyrimidinylisoindolines as AXL kinase inhibitors  Academic Article
• Design, synthesis, and biological evaluation of peptidomimetic inhibitors of factor XIa as novel anticoagulants  Academic Article
• Design, synthesis, and biological evaluation of simplified alpha-keto heterocycle, trifluoromethyl ketone, and formyl substituted folate analogues as potential inhibitors of GAR transformylase and AICAR transformylase  Academic Article
• Design, synthesis, and biological properties of highly potent epothilone b analogues  Academic Article
• Design, synthesis, and evaluation of an α-helix mimetic library targeting protein-protein interactions  Academic Article
• Design, synthesis, and evaluation of novel 3,6-diaryl-4-aminoalkoxyquinolines as selective agonists of somatostatin receptor subtype 2  Academic Article
• Design, synthesis, and evaluation of oxazole transthyretin amyloidogenesis inhibitors  Academic Article
• Design, synthesis, and evaluation of phe-gly mimetics: Heterocyclic building blocks for pseudopeptides  Academic Article
• Design, synthesis, and kinetic characterization of protein N-terminal acetyltransferase inhibitors  Academic Article
• Design, synthesis, and pharmacological evaluation of a novel series of pyridopyrazine-1,6-dione γ-secretase modulators  Academic Article
• Design, synthesis, and pharmacological evaluation of azetedine and pyrrolidine derivatives as dual norepinephrine reuptake inhibitors and 5-HT1A partial agonists  Academic Article
• Design, synthesis, and pharmacological evaluation of phenoxy pyridyl derivatives as dual norepinephrine reuptake inhibitors and 5-HT1A partial agonists  Academic Article
• Design, synthesis, and structure-activity-relationship of phenyl imidazoles as potent Smoothened antagonists  Academic Article
• Design, synthesis, and validation of a β-turn mimetic library targeting protein-protein and peptide-receptor interactions  Academic Article
• Design, synthesis, biological evaluation, and structural characterization of potent histone deacetylase inhibitors based on cyclic alpha/beta-tetrapeptide architectures  Academic Article
• Design, synthesis, enzyme-inhibitory activity, and effect on human cancer cells of a novel series of Jumonji domain-containing protein 2 histone demethylase inhibitors  Academic Article
• Designed enediynes - a new class of DNA-cleaving molecules with potent and selective anticancer activity  Academic Article
• Designed replacement of an internal hydration water molecule in bpti - structural and functional implications of a glycine-to-serine mutation  Academic Article
• Designer enediynes generate DNA breaks, interstrand cross-links, or both, with concomitant changes in the regulation of DNA damage responses  Academic Article
• Designing a broad-spectrum integrative approach for cancer prevention and treatment  Academic Article
• Designing arenaviral vaccines  Academic Article
• Designing facial amphiphiles for the stabilization of integral membrane proteins  Academic Article
• Desipramine treatment of alcoholism  Academic Article
• Destabilization of Ca2+-free gelsolin may not be responsible for proteolysis in Familial Amyloidosis of Finnish Type  Academic Article
• Destruction of the locus coeruleus or the dorsal ne bundle does not alter the release of punished responding by ethanol and chlordiazepoxide  Academic Article
• Detailed characterization of the peptide binding specificity of five common Patr class I MHC molecules  Academic Article
• Detailed mechanisms of the inactivation of factor viiia by activated protein c in the presence of its cofactors, protein s and factor v  Academic Article
• Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis  Academic Article
• Detecting and quantifying multiple proteins in clinical samples in high-throughput using antibody microarrays  Academic Article
• Detecting expression of 5T4 in CTCs and tumor samples from NSCLC patients  Academic Article
• Detecting genetic variation in microarray expression data  Academic Article
• Detection and characterization of low abundance cellular proteins that specifically increase upon loss of the metastatic phenotype  Academic Article
• Detection and isolation of dendritic cells using Lewis X-functionalized magnetic nanoparticles  Academic Article
• Detection and partial characterization of an inhibitor of plasminogen activator in human platelets  Academic Article
• Detection and partial characterization of circulating immune-complexes with solid-phase anti-c3  Academic Article
• Detection and quantification of plasma amyloid-β by selected reaction monitoring mass spectrometry  Academic Article
• Detection and quantitation of cleaved and uncleaved high molecular weight kininogen in plasma by ligand blotting with radiolabeled plasma prekallikrein or factor XI  Academic Article
• Detection and typing of herpes simplex viruses by using recombinant immunoglobulin fragments produced in bacteria  Academic Article
• Detection of 2 apolipoprotein-b species (apobc and apobg) by a monoclonal-antibody  Academic Article
• Detection of a 140 KDA nucleolar protein with an anti-PCNA autoantibody  Academic Article
• Detection of a nucleolar 7-2 ribonucleoprotein and a cytoplasmic 8-2 ribonucleoprotein with autoantibodies from patients with scleroderma  Academic Article
• Detection of a ternary complex of nf-kappa b and i kappa b alpha with DNA provides insights into how i kappa b alpha removes nf-kappa b from transcription sites  Academic Article
• Detection of active kallikrein in induced blister fluids of hereditary angioedema patients  Academic Article
• Detection of alkynes via click chemistry with a brominated coumarin azide by simultaneous fluorescence and isotopic signatures in mass spectrometry  Academic Article
• Detection of antibodies against the four subtypes of ebola virus in sera from any species using a novel antibody-phage indicator assay  Academic Article
• Detection of apoptosis in cartilage in situ and in isolated chondrocytes  Academic Article
• Detection of autoantibodies to recombinant mitochondrial proteins in patients with primary biliary-cirrhosis  Academic Article
• Detection of borna disease virus (bdv) antibodies and bdv rna in psychiatric patients: Evidence for high sequence conservation of human blood-derived bdv rna  Academic Article
• Detection of borna disease virus antigen and rna in human autopsy brain samples from neuropsychiatric patients  Academic Article