Humans

subject area of

"Don't know much bile-ology" Academic Article
"Resistance" to PSC-RANTES revisited: two mutations in human immunodeficiency virus type 1 HIV-1 SF162 or simian-human immunodeficiency virus SHIV SF162-p3 do not confer resistance Academic Article
"Viral deja vu" elicits organ-specific immune disease independent of reactivity to self Academic Article
'Late onset' ornithine transcarbamylase deficiency: function of three purified recombinant mutant enzymes Academic Article
'Muscle-sparing' statins: preclinical profiles and future clinical use Academic Article
'Reverse' alpha-ketoamide-based p38 map kinase inhibitors Academic Article
'SNO'-storms compromise protein activity and mitochondrial metabolism in neurodegenerative disorders Academic Article
'Translocatory proteins' and 'protein transduction domains': A critical analysis of their biological effects and the underlying mechanisms Academic Article
(18)F Fluoroazabenzoxazoles as potential amyloid plaque PET tracers: synthesis and in vivo evaluation in rhesus monkey Academic Article
(18)F-labeled isoindol-1-one and isoindol-1,3-dione derivatives as potential PET imaging agents for detection of beta-amyloid fibrils Academic Article
(4,2)D projection-reconstruction experiments for protein backbone assignment: application to human carbonic anhydrase II and calbindin D(28K) Academic Article
-Amino acid substitution of peptide-mediated NF-κB suppression in mdx mice preserves therapeutic benefit in skeletal muscle, but causes kidney toxicity Academic Article
1,3,8-Triazaspiro[4.5]decane-2,4-diones as efficacious pan-inhibitors of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) for the treatment of anemia Academic Article
1-(2-(2,2,2-Trifluoroethoxy)ethyl-1H-pyrazolo 4,3-d pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors Academic Article
1-(2-Ethoxyethyl)-1H-pyrazolo 4,3-d pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors Academic Article
1-H NMR detection of small molecules in human urine with a deep cavitand synthetic receptor Academic Article
1-deamino-8-D-arginine vasopressin and cryoprecipitate in variant von Willebrand disease Academic Article
1-deamino-8-D-arginine vasopressin: a new pharmacological approach to the management of haemophilia and von Willebrands' diseases Academic Article
1-year survival in a randomized trial of facilitated reperfusion results from the finesse (facilitated intervention with enhanced reperfusion speed to stop events) trial Academic Article
10-(2-benzoxazolcarbonyl)-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid: a potential inhibitor of GAR transformylase and AICAR transformylase Academic Article
10-formyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid (10-formyl-DDACTHF): a potent cytotoxic agent acting by selective inhibition of human GAR Tfase and the de novo purine biosynthetic pathway Academic Article
10-formyl-5,8,10-trideazafolic acid (10-formyl-TDAF): a potent inhibitor of glycinamide ribonucleotide transformylase Academic Article
100 cemented versus 100 noncemented stems with comparison of 25 matched pairs Academic Article
13C NMR studies of the product complex of glyoxalase I Academic Article
14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination Academic Article
14-3-3 proteins in neuronal development and function Academic Article
1H, 13C and 15N chemical shift assignments for the human Pitx2 homeodomain and a R24H homeodomain mutant Academic Article
2 cases of agammaglobulinemia detected by determining the blood group [Article in Russian] Academic Article
2-(3,5-dimethylphenyl)tryptamine derivatives that bind to the GnRH receptor Academic Article
2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: Design and synthesis of a potent and isoform selective PKC-zeta inhibitor Academic Article
2-(Pyrrolidin-1-yl)ethyl-3,4-dihydroisoquinolin-1(2H)-one Derivatives as Potent and Selective Histamine-3 Receptor Antagonists Academic Article
2-Amino- 1,2,4 triazolo 1,5-a pyridines as JAK2 inhibitors Academic Article
2-Amino-4-bis(aryloxybenzyl)aminobutanoic acids: A novel scaffold for inhibition of ASCT2-mediated glutamine transport Academic Article
2-Aminobenzimidazoles as potent Aurora kinase inhibitors Academic Article
2-Arylbenzoxazoles as novel cholesteryl ester transfer protein inhibitors: optimization via array synthesis Academic Article
2-Bromopalmitate analogues as activity-based probes to explore palmitoyl acyltransferases Academic Article
2-Chlorodeoxyadenosine activity in patients with untreated, indolent non-Hodgkin's lymphoma Academic Article
2-Propylthiouracil does not replace glutathione for the glutathione transferases Academic Article
2-chlorodeoxyadenosine in the treatment of chronic refractory immune thrombocytopenic purpura Academic Article
2-microglobulin: a free immunoglobulin domain Academic Article
2-year outcome after angiographically documented myocardial reperfusion for acute coronary-occlusion Academic Article
2010 white paper on recent issues in regulated bioanalysis & global harmonization of bioanalytical guidance Academic Article
24 hours in the life of HIV-1 in a T cell line Academic Article
28th Bethesda Conference. Task force 5: Assessment, approval, and regulation of new technology Academic Article
384 hanging drop arrays give excellent Z-factors and allow versatile formation of co-culture spheroids Academic Article
4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)pi perazine-1-carbothioamide (ML267), a Potent Inhibitor of Bacterial Phosphopantetheinyl Transferase That Attenuates Secondary Metabolism and Thwarts Bacterial Growth Academic Article
4-Aminoindazolyl-dihydrofuro 3,4-d pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase Academic Article
4-Aminopyridyl-based CYP51 inhibitors as anti-Trypanosoma cruzi drug leads with improved pharmacokinetic profile and in vivo potency Academic Article
4-Methyl-6,7-dihydro-4H-triazolo 4,5-c pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidate Academic Article
4-O-acetyl-N-acetylneuraminic acid in the N-linked carbohydrate structures of equine and guinea pig alpha 2-macroglobulins, potent inhibitors of influenza virus infection Academic Article
4E10-resistant HIV-1 isolated from four subjects with rare membrane-proximal external region polymorphisms Academic Article
5 alpha-Androstan-3 alpha,17 beta-diol is a hormone: stimulation of cAMP accumulation in human and dog prostate Academic Article
5-HT(2C) agonists as therapeutics for the treatment of schizophrenia Academic Article
5-ht(1a) receptor binding is increased after recovery from bulimia nervosa compared to control women and is associated with behavioral inhibition in both groups Academic Article
5-lipoxygenase-activating protein inhibitors: development of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM103) Academic Article
68Ga-PSMA-11 PET imaging of response to androgen receptor inhibition: first human experience Academic Article
7-Hydroxynaphthalen-1-yl-urea and -amide antagonists of human vanilloid receptor 1 Academic Article
7-alkylidenecephalosporin esters as inhibitors of human leukocyte elastase Academic Article
8-Hydroxyquinoline and hydroxamic acid inhibitors of botulinum neurotoxin BoNT/A Academic Article
8-Tetrahydropyran-2-yl chromans: highly selective beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors Academic Article
9p21 DNA variants associated with coronary artery disease impair interferon-gamma signalling response Academic Article
A "flip-flop" rotation stage for routine dual-axis electron cryotomography Academic Article
A 15-ketosterol is a liver X receptor ligand that suppresses sterol-responsive element binding protein-2 activity Academic Article
A 193-amino acid fragment of the SARS coronavirus S protein efficiently binds angiotensin-converting enzyme 2 Academic Article
A 3-dimensional extracellular matrix as a delivery system for the transplantation of glioma-targeting neural stem/progenitor cells Academic Article
A 46-nucleotide promoter segment from an IFN-alpha gene renders an unrelated promoter inducible by virus Academic Article
A 50-kDa membrane protein mediates sialic acid-independent binding and infection of conjunctival cells by adenovirus type 37 Academic Article
A 52-kD protein is a novel component of the SS-A/Ro antigenic particle Academic Article
A 9-nt segment of a cellular mRNA can function as an internal ribosome entry site (IRES) and when present in linked multiple copies greatly enhances IRES activity Academic Article
A Bellagio consensus. Children's Vaccine Initiative Ad Hoc Committe on an investment strategy for measles control Academic Article
A CAT reporter construct allows ultrasensitive estimation of TNF synthesis, and suggests that the TNF gene has been silenced in non-macrophage cell lines Academic Article
A Clinical Indications Prediction Scale Based on TWIST1 for Human Mesenchymal Stem Cells Academic Article
A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response Academic Article
A DNA vaccine for ebola virus is safe and immunogenic in a phase i clinical trial Academic Article
A GTP affinity probe for proteomics highlights flexibility in purine nucleotide selectivity Academic Article
A HaloTag-based multicolor fluorogenic sensor visualizes and quantifies proteome stress in live cells using solvatochromic and molecular rotor-based fluorophores Academic Article
A LC-MS-based workflow for measurement of branched fatty acid esters of hydroxy fatty acids Academic Article
A New World primate deficient in tetherin-mediated restriction of human immunodeficiency virus type 1 Academic Article
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis Academic Article
A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate Academic Article
A Plasmodium gene family encoding Maurer's cleft membrane proteins: structural properties and expression profiling Academic Article
A SNAP-tag fluorogenic probe mimicking the chromophore of the red fluorescent protein Kaede Academic Article
A THEMIS:SHP1 complex promotes T-cell survival Academic Article
A TRP channel that senses cold stimuli and menthol Academic Article
A Yersinia-pseudotuberculosis protein which cross-reacts with HLA-B27 Academic Article
A bifunctional molecule that displays context-dependent cellular activity Academic Article
A binary plasmid system for shuffling combinatorial antibody libraries Academic Article
A biochemically distinct sub-population of neurons in the human substantia gelatinosa. Study with G-6-PD histochemistry Academic Article
A bioinformatic assay for pluripotency in human cells Academic Article
A biomechanical evaluation of three surgical techniques for subscapularis repair Academic Article
A biomechanical study of the aponeurotic inguinal hernia repair Academic Article
A biosynthetic approach for the incorporation of unnatural amino acids into proteins Academic Article
A biparatopic HER2-targeting antibody-drug conjugate induces tumor regression in primary models refractory to or ineligible for HER2-targeted therapy Academic Article
A bleeding disorder due to deficiency of alpha-2-antiplasmin Academic Article
A blood based 12-miRNA signature of Alzheimer disease patients Academic Article
A blueprint for HIV vaccine discovery Academic Article
A brave new MYC-amplified world Academic Article
A brief review of the past and future of platelet P2Y12 antagonist Academic Article
A broadly neutralizing human monoclonal antibody exhibits in vivo efficacy against both human metapneumovirus and respiratory syncytial virus Academic Article
A c-alpha model for the transmembrane alpha helices of gap junction intercellular channels Academic Article
A call for action on primary care and public health integration Academic Article
A camera-phone based study reveals erratic eating pattern and disrupted daily eating-fasting cycle among adults in India Academic Article
A candidate circuit approach to investigating autism Academic Article
A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase Academic Article
A candidate live inactivatable attenuated vaccine for aids Academic Article
A carbohydrate-conjugated deep cavitand permits observation of caviplexes in human serum Academic Article
A carbohydrate-derived splice modulator Academic Article
A case of an entrapped rotational atherectomy burr Academic Article
A case study on forensic polymer analysis by dios-ms: The suspect who gave us the slip (r) Academic Article
A catechol-O-methyltransferase that is essential for auditory function in mice and humans Academic Article
A cd4+ cytotoxic lymphocyte-t clone to a conserved epitope on human-immunodeficiency-virus type-1 p24 - cytotoxic activity and secretion of interleukin-2 and interleukin-6 Academic Article
A cdc6 protein-binding peptide selected using a bacterial two-hybrid-like system is a cell cycle inhibitor Academic Article
A cell-based luciferase assay amenable to high-throughput screening of inhibitors of arenavirus budding Academic Article
A cell-cycle nuclear autoantigen containing WD-40 motifs expressed mainly in S and G2 phase cells Academic Article
A cell-cycle-regulated inhibitor of cyclin-dependent kinases Academic Article
A cell-free expression and purification process for rapid production of protein biologics Academic Article
A cell-penetrating peptide from a novel pVII-pIX phage-displayed random peptide library Academic Article
A cell-penetrating peptidic GRP78 ligand for tumor cell-specific prodrug therapy Academic Article
A cell-permeable synthetic transcription factor mimic Academic Article
A cellular gene encodes scrapie prp 27-30 protein Academic Article
A central strategy for converting natural products into fluorescent probes Academic Article
A change in the conformation of prions accompanies the emergence of a new prion strain Academic Article
A chaperone trap contributes to the onset of cystic fibrosis Academic Article
A chemical approach for detecting sulfenic acid-modified proteins in living cells Academic Article
A chemical approach for the detection of protein sulfinylation Academic Article
A chemical approach to stem cell biology Academic Article
A chemical approach to stem-cell biology and regenerative medicine Academic Article
A chemical biology approach reveals period shortening of the mammalian circadian clock by specific inhibition of GSK-3β Academic Article
A chemical chaperone decouples TDP-43 disordered domain phase separation from fibrillation Academic Article
A chemical genomic analysis of decoquinate, a plasmodium falciparum cytochrome b inhibitor Academic Article
A chemical platform for improved induction of human iPSCs Academic Article
A chemical switch for inhibitor-sensitive alleles of any protein kinase Academic Article
A chemical switch regulates fibrate specificity for peroxisome proliferator-activated receptor alpha (ppar alpha) versus liver x receptor Academic Article
A chemical, genetic, and structural analysis of the nuclear bile acid receptor fxr Academic Article
A chemically functionalized magnetic nanoplatform for rapid and specific biomolecular recognition and separation Academic Article
A chemically induced vaccine strategy for prostate cancer Academic Article
A chemically programmed antibody is a long-lasting and potent inhibitor of influenza neuraminidase Academic Article
A chemically stable fluorescent marker of the ureter Academic Article
A chemo-enzymatic approach to the study of carbohydrate recognition in biological systems Academic Article
A chemoproteomic platform to quantitatively map targets of lipid-derived electrophiles Academic Article
A child with fever after hematopoietic stem cell transplantation Academic Article
A chimeric hiv-1 envelope glycoprotein trimer with an embedded granulocyte-macrophage colony-stimulating factor (gm-csf) domain induces enhanced antibody and t cell responses Academic Article
A chloroacetamidine-based inactivator of protein arginine methyltransferase 1: Design, synthesis, and in vitro and in vivo evaluation Academic Article
A chromatin binding-site in the tail domain of nuclear lamins that interacts with core histones Academic Article
A clinical study of an unusual case of asthma associated with urticaria pigmentosa Academic Article
A clinical trial comparing primary coronary angioplasty with tissue plasminogen activator for acute myocardial infarction Academic Article
A coactivator trap identifies NONO (p54(nrb)) as a component of the cAMP-signaling pathway Academic Article
A code for RanGDP binding in ankyrin repeats defines a nuclear import pathway Academic Article
A colorectal cancer classification system that associates cellular phenotype and responses to therapy Academic Article
A combination of docking/dynamics simulations and pharmacophoric modeling to discover new dual c-Src/Abl kinase inhibitors Academic Article
A combination of low-dose cyclophosphamide and colony-stimulating factors is more cost-effective than granulocyte-colony-stimulating factors alone in mobilizing peripheral blood stem and progenitor cells Academic Article
A combinatorial approach to characterize the substrate specificity of protein arginine methyltransferase 1 Academic Article
A combined chemical and genetic approach for the generation of induced pluripotent stem cells Academic Article
A combined proteomics/genomics approach links hepatitis C virus infection with nonsense-mediated mRNA decay Academic Article
A common MECP2 haplotype associates with reduced cortical surface area in humans in two independent populations Academic Article
A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to Legionnaires' disease Academic Article
A common genetic polymorphism (46 C to T substitution) in the 5 '-untranslated region of the coagulation factor XII gene is associated with low translation efficiency and decrease in plasma factor XII level Academic Article
A common pharmacophore for epothilone and taxanes: Molecular basis for drug resistance conferred by tubulin mutations in human cancer cells Academic Article
A common promoter variant of the leptin gene is associated with changes in the relationship between serum leptin and fat mass in obese girls Academic Article
A common solution to group 2 influenza virus neutralization Academic Article
A comparative analysis of HGSC and Celera human genome assemblies and gene sets Academic Article
A comparative encyclopedia of DNA elements in the mouse genome Academic Article
A comparative immunogenicity study of hiv-1 virus-like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble monomeric gp120 Academic Article
A comparison between activated protein C and des-1-41-light chain-activated protein C in reactions with type 1 plasminogen activator inhibitor Academic Article
A comparison of cf and non-cf school-age children undergoing lung transplantation Academic Article
A comparison of debulking versus dilatation of bifurcation coronary arterial narrowings (from the caveat i trial) Academic Article
A comparison of directional atherectomy with coronary angioplasty in patients with coronary-artery disease Academic Article
A comparison of ionic versus nonionic contrast medium during primary percutaneous transluminal coronary angioplasty for acute myocardial infarction (gusto iib) Academic Article
A comparison of linear and cyclic peptoid oligomers as potent antimicrobial agents Academic Article
A comparison of noninternalizing (herkinorin) and internalizing (DAMGO) mu-opioid agonists on cellular markers related to opioid tolerance and dependence Academic Article
A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes Academic Article
A comparison of reteplase with alteplase for acute myocardial infarction Academic Article
A comparison of selected quantitative trait loci associated with alcohol use phenotypes in humans and mouse models Academic Article
A comparison of the Celera and Ensembl predicted gene sets reveals little overlap in novel genes Academic Article
A comparison of the abilities of plasma kallikrein, beta-Factor XIIa, Factor XIa and urokinase to activate plasminogen Academic Article
A comparison of the atomic model of F-actin with cryo-electron micrographs of actin and decorated actin Academic Article
A comparison of the enzymatic and physicochemical properties of human glutathione transferase M4-4 and three other human Mu class enzymes Academic Article
A comparison of two neurologic scoring instruments for multiple sclerosis Academic Article
A compass for stem-cell differentiation Academic Article
A competition assay to identify amyloidogenesis inhibitors by monitoring the fluorescence emitted by the covalent attachment of a stilbene derivative to transthyretin Academic Article
A complex equilibrium among partially unfolded conformations in monomeric transthyretin Academic Article
A complex of Protocadherin-19 and N-cadherin mediates a novel mechanism of cell adhesion Academic Article
A complexin/synaptotagmin 1 switch controls fast synaptic vesicle exocytosis Academic Article
A complexity measure for selective matching of signals by the brain Academic Article
A comprehensive approach to zinc-finger recombinase customization enables genomic targeting in human cells Academic Article
A computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein induces apoptosis in infected cells Academic Article
A concise and flexible synthesis of the potent anti-influenza agents tamiflu and tamiphosphor Academic Article
A conformational switch in human immunodeficiency virus gp41 revealed by the structures of overlapping epitopes recognized by neutralizing antibodies Academic Article
A consensus-hemagglutinin-based DNA vaccine that protects mice against divergent H5N1 influenza viruses Academic Article
A conserved "hydrophobic staple motif" plays a crucial role in the refolding of human glutathione transferase P1-1 Academic Article
A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis Academic Article
A conserved family of prolyl-4-hydroxylases that modify HIF Academic Article
A conserved hiv gp120 glycoprotein structure involved in chemokine receptor binding Academic Article
A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase Academic Article
A conserved motif in the itk ph-domain is required for phosphoinositide binding and tcr signaling but dispensable for adaptor protein interactions Academic Article
A conserved proliferating cell nuclear antigen-interacting protein sequence in Chk1 is required for checkpoint function Academic Article
A conserved protein interaction interface on the type 5 G protein beta subunit controls proteolytic stability and activity of R7 family regulator of G protein signaling proteins Academic Article
A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension Academic Article
A contemporary assessment of low-molecular-weight heparin for the treatment of acute coronary syndromes: Factoring in new trials and meta-analysis data Academic Article
A continuous, spectroscopic analysis of the kinetics of elastase secretion by neutrophils. The dependence of secretion upon receptor occupancy Academic Article
A cost-effective fluorescence mini-microscope for biomedical applications Academic Article
A credit-card library approach for disrupting protein-protein interactions Academic Article
A critical analysis of codon optimization in human therapeutics Academic Article
A critical evaluation of enzyme immunoassay kits for detection of antinuclear autoantibodies of defined specificities. II. Potential for quantitation of antibody content Academic Article
A critical evaluation of enzyme immunoassay kits for detection of antinuclear autoantibodies of defined specificities. III. Comparative performance characteristics of academic and manufacturers' laboratories Academic Article
A critical evaluation of enzyme immunoassays for detection of antinuclear autoantibodies of defined specificities. I. Precision, sensitivity, and specificity Academic Article
A critical role for Pin2/TRF1 in ATM-dependent regulation. Inhibition of Pin2/TRF1 function complements telomere shortening, radiosensitivity, and the G(2)/M checkpoint defect of ataxia-telangiectasia cells Academic Article
A critical role for TORC1 in cellular senescence Academic Article
A critical role for monocytes and cd14 in endotoxin-induced endothelial-cell activation Academic Article
A critical role for the sphingosine analog aal-r in dampening the cytokine response during influenza virus infection Academic Article
A critical role of the C-terminal segment for allosteric inhibitor-induced aberrant multimerization of HIV-1 integrase Academic Article
A cross-over inhibitor of the botulinum neurotoxin light chain B: A natural product implicating an exosite mechanism of action Academic Article
A cross-species analysis in pancreatic neuroendocrine tumors reveals molecular subtypes with distinctive clinical, metastatic, developmental, and metabolic characteristics Academic Article
A cross-species analysis of a mouse model of breast cancer-specific osteolysis and human bone metastases using gene expression profiling Academic Article
A crucial role of mitochondrial Hsp40 in preventing dilated cardiomyopathy Academic Article
A crystal structure of a model of the repeating r(CGG) transcript found in fragile X syndrome Academic Article
A curcumin derivative that inhibits vinyl carbamate-induced lung carcinogenesis via activation of the Nrf2 protective response Academic Article
A customized self-assembling peptide hydrogel for dental pulp tissue engineering Academic Article
A cyclin-dependent kinase inhibitor inducing cancer cell differentiation: biochemical identification using Xenopus egg extracts Academic Article
A decrease in the size of the basal ganglia following prenatal alcohol exposure - a preliminary-report Academic Article
A defective V-kappa A2 allele in navajos which play play a role in increased susceptibility to haemophilus influenzae type disease Academic Article
A demonstration of the intrinsic importance of stabilizing hydrophobic binding and noncovalent van der Waals contacts dominant in the noncovalent CC-1065/b-DNA binding Academic Article
A designed peptidomimetic agonistic ligand of trka nerve growth factor receptors Academic Article
A di-acidic (DxE) code directs concentration of cargo during export from the endoplasmic reticulum Academic Article
A diffuse infiltrative CD8 lymphocytosis syndrome in human immunodeficiency virus (HIV) infection: a host immune response associated with HLA-DR5 Academic Article
A direct comparison of tirofiban and abciximab during percutaneous coronary revascularization and stent placement: rationale and design of the TARGET study Academic Article
A direct enzymatic assay for the esterolytic activity of activated hageman factor Academic Article
A direct, plasmin-independent assay for plasminogen activator Academic Article
A discovery strategy for selective inhibitors of c-Src in complex with the focal adhesion kinase SH3/SH2-binding region Academic Article
A disease-specific measure of health-related quality of life for use in adults with immune thrombocytopenic purpura: Its development and validation Academic Article
A disease-specific measure of health-related quality of life in adults with chronic immune thrombocytopenic purpura: Psychometric testing in an open-label clinical trial Academic Article
A distinct reactive oxygen species profile confers chemoresistance in glioma-propagating cells and associates with patient survival outcome Academic Article
A distinct slow cellular pathway involving soluble mediators for the t-cell-instructed induction of monocyte tissue factor activity in an allogeneic immune-response Academic Article
A dominant-negative peroxisome proliferator-activated receptor gamma (ppar gamma) mutant is a constitutive repressor and inhibits ppar gamma-mediated adipogenesis Academic Article
A double monoclonal IgG1k and IgG2k in a single myeloma patient - variation in clonal products and therapeutic responses Academic Article
A double-blind, placebo-controlled pilot study to evaluate the efficacy and safety of oral nalmefene HCl for alcohol dependence Academic Article
A double-blind, placebo-controlled study of oral nalmefene for alcohol dependence Academic Article
A double-blind, placebo-controlled trial of desipramine for primary alcohol dependence stratified on the presence or absence of major depression Academic Article
A double-blind, placebo-controlled, randomized trial of cladribine in relapsing-remitting multiple sclerosis Academic Article
A double-mimetic peptide efficiently neutralizes HIV-1 by bridging the CD4- and coreceptor-binding sites of gp120 Academic Article
A double-stranded rna-activated protein kinase-dependent pathway mediating stress-induced apoptosis Academic Article
A double-variant transthyretin allele (Ser-6, Ile-33) in the israeli patient SKO with familial amyloidotic polyneuropathy Academic Article
A downstream kinase of the mammalian target of rapamycin, p70s6k1, regulates human double minute 2 protein phosphorylation and stability Academic Article
A drosophila g(1)-specific cyclin e homolog exhibits different modes of expression during embryogenesis Academic Article
A dual array-based approach to assess the abundance and posttranslational modification state of signaling proteins Academic Article
A dual color immunohistochemistry assay for measurement of cereblon in multiple myeloma patient samples Academic Article
A dynamic model of HIV integrase inhibition and drug resistance Academic Article
A dynamic search process underlies microRNA targeting Academic Article
A dynamin mutant defines a superconstricted prefission state Academic Article
A dystroglycan mutation associated with limb-girdle muscular dystrophy Academic Article
A facile system for encoding unnatural amino acids in mammalian cells Academic Article
A factor IX-deficient mouse model for hemophilia B gene therapy Academic Article
A family of cyclin homologs that control the g1 phase in yeast Academic Article
A family of leukemia inhibitory factor-binding peptides that can act as antagonists when conjugated to poly(ethylene glycol) Academic Article
A family of lipopolysaccharide binding-proteins involved in responses to gram-negative sepsis Academic Article
A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange Academic Article
A feasibility study showing [68Ga]citrate PET detects prostate cancer Academic Article
A fibroblast growth factor binding protein in human cerebral spinal fluid Academic Article
A five-amino-acid motif in the undefined region of the tlr8 ectodomain is required for species-specific ligand recognition Academic Article
A fluopol-ABPP HTS assay to identify PAD inhibitors Academic Article
A fluorescence-based thiol quantification assay for ultra-high-throughput screening for inhibitors of coenzyme a production Academic Article
A fluorescent plate reader assay for ceramide kinase Academic Article
A fluorogenic aryl fluorosulfate for intraorganellar transthyretin imaging in living cells and in Caenorhabditis elegans Academic Article
A fluorometric assay for red-blood-cell antibodies Academic Article
A focused microarray approach to functional glycomics: Transcriptional regulation of the glycome Academic Article
A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function Academic Article
A fragment of human TrpRS as a potent antagonist of ocular angiogenesis Academic Article
A fully active catalytic domain of bovine aspartyl (asparaginyl) beta-hydroxylase expressed in Escherichia-coli: characterization and evidence for the identification of an active-site region in vertebrate alpha-ketoglutarate-dependent dioxygenases Academic Article
A functional genomics approach to the mode of action of apratoxin A Academic Article
A functional genomics strategy reveals Rora as a component of the mammalian circadian clock Academic Article
A functional interaction between RIP140 and PGC-1 alpha regulates the expression of the lipid droplet protein CIDEA Academic Article
A gdp-bound form of rab1 inhibits protein export from the endoplasmic-reticulum and transport between golgi compartments Academic Article
A gender-specific blood-based gene expression score for assessing obstructive coronary artery disease in nondiabetic patients: Results of the personalized risk evaluation and diagnosis in the coronary tree (predict) trial Academic Article
A gene atlas of the mouse and human protein-encoding transcriptomes Academic Article
A gene encoding an intestinal-enriched member of the Kruppel-like factor family expressed in intestinal epithelial cells Academic Article
A gene expression phenotype in lymphocytes from Friedreich ataxia patients Academic Article
A gene expression profile of alzheimer's disease Academic Article
A gene expression profile of embryonic stem cells and embryonic stem cell-derived neurons Academic Article
A gene for hirschsprung disease (megacolon) in the pericentromeric region of human chromosome-10 Academic Article
A gene-specific role for the Ssu72 RNAPII CTD phosphatase in HIV-1 Tat transactivation Academic Article
A general approach for receptor and antibody-targeted detection of native proteins utilizing split-luciferase reassembly Academic Article
A general approach to site-specific antibody drug conjugates Academic Article
A general method for insertion of functional proteins within proteins via combinatorial selection of permissive junctions Academic Article
A general method to quantify quasi-equivalence in icosahedral viruses Academic Article
A general system for evaluating the efficiency of chromophore-assisted light inactivation (CALI) of proteins reveals Ru(ii) tris-bipyridyl as an unusually efficient "warhead" Academic Article
A genetic analysis of pax3-fkhr, the oncogene of alveolar rhabdomyosarcoma Academic Article
A genetic determinant of the striatal dopamine response to alcohol in men Academic Article
A genetic network that suppresses genome rearrangements in Saccharomyces cerevisiae and contains defects in cancers Academic Article
A genetically encoded aza-Michael acceptor for covalent cross-linking of protein-receptor complexes Academic Article
A genetically encoded fluorescent amino acid Academic Article
A genetically encoded fluorescent probe in mammalian cells Academic Article
A genetically encoded multifunctional TRAIL trimer facilitates cell-specific targeting and tumor cell killing Academic Article
A genetically encoded photocaged amino acid Academic Article
A genetically humanized mouse model for hepatitis C virus infection Academic Article
A genome sequencing program for novel undiagnosed diseases Academic Article
A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control Academic Article
A genome-wide RNAi screen for modifiers of the circadian clock in human cells Academic Article
A genome-wide association study of anorexia nervosa Academic Article
A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A Academic Article
A genome-wide association study on common snps and rare cnvs in anorexia nervosa Academic Article
A genome-wide linkage analysis investigating the determinants of blood pressure in whites and african americans Academic Article
A genome-wide linkage scan identifies multiple quantitative trait loci for hdl-cholesterol levels in families with premature cad and mi Academic Article
A genome-wide scan for linkage to chromosomal regions in 382 sibling pairs with schizophrenia or schizoaffective disorder Academic Article
A genome-wide scan for loci linked to forearm bone mineral density Academic Article
A genome-wide search for chromosomal loci linked to mental health wellness in relatives at high risk for bipolar affective disorder among the old order amish Academic Article
A genome-wide search for schizophrenia susceptibility genes Academic Article
A genomewide analysis provides evidence for novel linkages in inflammatory bowel disease in a large european cohort Academic Article
A genomewide scan of male sexual orientation Academic Article
A genomic screen identifies TYRO3 as a MITF regulator in melanoma Academic Article
A genomic-systems biology map for cardiovascular function Academic Article
A geographic cline of skull and brain morphology among individuals of european ancestry Academic Article
A gfp-equipped bidirectional expression module well suited for monitoring tetracycline-regulated gene expression in mouse Academic Article
A glimpse of a possible amyloidogenic intermediate of transthyretin Academic Article
A global assessment of stem cell engineering Academic Article
A global map of lipid-binding proteins and their ligandability in cells Academic Article
A global metabolite profiling approach to identify protein-metabolite interactions Academic Article
A global view of atherothrombosis: baseline characteristics in the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance (CHARISMA) trial Academic Article
A glutamate switch controls voltage-sensitive phosphatase function Academic Article
A glycoengineered enzyme with multiple mannose-6-phosphates is internalized into diseased cells to restore its activity in lysosomes Academic Article
A golden-age for adhesion Academic Article
A gp41 MPER-specific llama VHH requires a hydrophobic CDR3 for neutralization but not for antigen recognition Academic Article
A growing family of receptor genes for lysophosphatidic acid (LPA) and other lysophospholipids (LPs) Academic Article
A gtpase distinct from ran is involved in nuclear protein import Academic Article
A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival Academic Article
A haplotype map of the human genome Academic Article
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A role for ranbp1 in the release of crm1 from the nuclear pore complex in a terminal step of nuclear export Academic Article
A role for rev-erb alpha ligands in the regulation of adipogenesis Academic Article
A role for stem cell biology in the physiological and pathological aspects of aging Academic Article
A role for the P-body component GW182 in microRNA function Academic Article
A role for the mevalonate pathway in the induction of subtype cross-reactive immunity to influenza a virus by human gamma 6 t lymphocytes Academic Article
A role for tissue factor in cell adhesion and migration mediated by interaction with actin-binding protein 280 Academic Article
A role for von Willebrand factor proline residues 702-704 in ristocetin-mediated binding to platelet glycoprotein Ib Academic Article
A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition Academic Article
A rugged energy landscape mechanism for trapping of transmembrane receptors during endocytosis Academic Article
A sample selection strategy to boost the statistical power of signature detection in cancer expression profile studies Academic Article
A schizophrenia-susceptibility locus at 6q25, in one of the world's largest reported pedigrees Academic Article
A screening platform for glioma growth and invasion using bioluminescence imaging Academic Article
A screening-based approach to circumvent tumor microenvironment-driven intrinsic resistance to BCR-ABL+ inhibitors in Ph+ acute lymphoblastic leukemia Academic Article
A search for association between schizophrenia and dopamine-related alleles Academic Article
A second binding site for hydroxytamoxifen within the coactivator-binding groove of estrogen receptor beta Academic Article
A second class of nuclear receptors for oxysterols: Regulation of ROR alpha and ROR gamma activity by 24S-hydroxycholesterol (cerebrosterol) Academic Article
A second fatty acid amide hydrolase with variable distribution among placental mammals Academic Article
A second generation human haplotype map of over 3.1 million SNPs Academic Article
A second mammalian n-myristoyltransferase Academic Article
A second-generation combined linkage-physical map of the human genome Academic Article
A selective defect in tissue factor messenger-rna expression in monocytes from aids patients Academic Article
A selective estrogen receptor modulator for the treatment of hot flushes Academic Article
A selective inhibitor Gal-PUGNAc of human lysosomal beta-hexosaminidases modulates levels of the ganglioside GM2 in neuroblastoma cells Academic Article
A selective irreversible inhibitor targeting a PDZ protein interaction domain Academic Article
A self-assembly pathway to aligned monodomain gels Academic Article
A semisynthetic carbohydrate-lipid vaccine that protects against S-pneumoniae in mice Academic Article
A sensitive elisa for measuring recombinant human interleukin-3 in human plasma or serum Academic Article
A sensitive method for measuring neutralizing antibodies to Bordetella pertussis toxin: optimized ADP-ribosylation of transducin Academic Article
A sensitive ristocetin co-factor activity assay with recombinant glycoprotein Ib alpha for the diagnosis of patients with low von Willebrand factor levels Academic Article
A separable domain of the p150 subunit of human chromatin assembly factor-1 promotes protein and chromosome associations with nucleoli Academic Article
A sequence analysis of von Willebrand factor mRNA, gene, and pseudogene in two patients with von Willebrand disease type 2B, and an investigation of gene conversion in its gene Academic Article
A shared structural solution for neutralizing ebolaviruses Academic Article
A short n-terminal sequence of pten controls cytoplasmic localization and is required for suppression of cell growth Academic Article
A short segment of the hiv-1 gp120 v1/v2 region is a major determinant of resistance to v1/v2 neutralizing antibodies Academic Article
A shotgun proteomic method for the identification of membrane-embedded proteins and peptides Academic Article
A shotgun proteomic study of the protein corona associated with cholesterol and atheronal-b surface-modified quantum dots Academic Article
A sibship with hypokalemic alkalosis and renal proximal tubulopathy Academic Article
A siglec-like sialic-acid-binding motif revealed in an adenovirus capsid protein Academic Article
A silencer element in the retinoblastoma tumor-suppressor gene Academic Article
A sim-ultaneous role for SUMO and ubiquitin Academic Article
A simple design for a double-tunable probe head for imaging and spectroscopy at high fields Academic Article
A simple ligation-based method to increase the information density in sequencing reactions used to deconvolute nucleic acid selections Academic Article
A simple solid phase, peptide-based fluorescent assay for the efficient and universal screening of hrv 3c protease inhibitors Academic Article
A simplified cloning strategy for the generation of an endothelial cell selective recombinant adenovirus vector Academic Article
A simulation-based analysis of chromosome segment sharing among a group of arbitrarily related individuals Academic Article
A single amino acid change in the binding pocket alters specificity of an anti-integrin antibody AP7.4 as revealed by its crystal structure Academic Article
A single amino acid in the adenovirus type 37 fiber confers binding to human conjunctival cells Academic Article
A single amino-acid change in the mouse peroxisome proliferator-activated receptor-alpha alters transcriptional responses to peroxisome proliferators Academic Article
A single copy of apolipoprotein b-48 is present on the human chylomicron remnant Academic Article
A single genetic origin for a common caucasian risk factor for venous thrombosis Academic Article
A single glycine in extracellular loop 1 is the critical determinant for pharmacological specificity of dopamine D2 and D3 receptors Academic Article
A single human papillomavirus vaccine dose improves B cell memory in previously infected subjects Academic Article
A single immunoglobulin-like domain of the human neural cell adhesion molecule L1 supports adhesion by multiple vascular and platelet integrins Academic Article
A single maturation cleavage site in adenovirus impacts cell entry and capsid assembly Academic Article
A single nucleotide difference in the gene for myelin proteolipid protein defines the jimpy mutation in mouse Academic Article
A single receptor encoded by vzg-1/lpA1/edg-2 couples to G proteins and mediates multiple cellular responses to lysophosphatidic acid Academic Article
A single thymine nucleotide deletion responsible for congenital deficiency of plasmin inhibitor Academic Article
A single vertebrate DNA virus protein disarms invertebrate immunity to RNA virus infection Academic Article
A single-cell roadmap of lineage bifurcation in human ESC models of embryonic brain development Academic Article
A single-subunit nadh-quinone oxidoreductase renders resistance to mammalian nerve cells against complex i inhibition Academic Article
A slice of PAI Academic Article
A small GTPase molecular switch regulates epigenetic centromere maintenance by stabilizing newly incorporated CENP-A Academic Article
A small diversity library of α-methyl amide analogs of sulindac for probing anticancer structure-activity relationships Academic Article
A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase Academic Article
A small molecule RAS-mimetic disrupts RAS association with effector proteins to block signaling Academic Article
A small molecule bidentate-binding dual inhibitor probe of the LRRK2 and JNK kinases Academic Article
A small molecule bidentate-binding dual inhibitor probe of the LRRK2 and JNK kinases Academic Article
A small molecule inhibitor of α4 integrin-dependent cell migration Academic Article
A small molecule inhibits deregulated NRF2 transcriptional activity in cancer Academic Article
A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth Academic Article
A small molecule modulates circadian rhythms through phosphorylation of the period protein Academic Article
A small molecule neutrophil elastase inhibitor, KRP-109, inhibits cystic fibrosis mucin degradation Academic Article
A small molecule primes embryonic stem cells for differentiation Academic Article
A small molecule promotes mitochondrial fusion in mammalian cells Academic Article
A small molecule that binds and inhibits the ETV1 transcription factor oncoprotein Academic Article
A small molecule that directs differentiation of human ESCs into the pancreatic lineage Academic Article
A small molecule that mimics the BB-loop in the Toll Interleukin-1 (IL-1) receptor domain of MyD88 attenuates Staphylococcal enterotoxin B-induced pro-inflammatory cytokine production and toxicity in mice Academic Article
A small ubiquitin-related polypeptide involved in targeting rangap1 to nuclear pore complex protein ranbp2 Academic Article
A small-molecule antagonist of the hedgehog signaling pathway Academic Article
A small-molecule inducer of the antioxidant response element Academic Article
A smartphone app reveals erratic diurnal eating patterns in humans that can be modulated for health benefits Academic Article
A solid-phase radioimmunoassay for anti-histone antibodies in human sera: comparison with an immunofluorescence assay Academic Article
A soluble alpha-synuclein construct forms a dynamic tetramer Academic Article
A soluble single-chain T-cell receptor IL-2 fusion protein retains MHC-restricted peptide specificity and IL-2 bioactivity Academic Article
A somatic-cell hybrid map of human-chromosome-13 Academic Article
A specific assay for anti-hla antibodies - application to platelet donor selection Academic Article
A specific cholesterol binding site is established by the 2.8 Å structure of the human β2-adrenergic receptor Academic Article
A specific interaction between the telomeric protein Pin2/TRF1 and the mitotic spindle Academic Article
A specific interaction of small molecule entry inhibitors with the envelope glycoprotein complex of the Junin hemorrhagic fever arenavirus Academic Article
A specific protein disorder catalyzer of HIV-1 Nef Academic Article
A sphingosine 1-phosphate receptor 2 selective allosteric agonist Academic Article
A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen Academic Article
A stapled p53 helix overcomes HDMX-mediated suppression of p53 Academic Article
A steady-state-kinetic model for formaldehyde dehydrogenase from human liver. A mechanism involving NAD+ and the hemimercaptal adduct of glutathione and formaldehyde as substrates and free glutathione as an allosteric activator of the enzyme Academic Article
A stem cell-based approach to cartilage repair Academic Article
A step-wise approach significantly enhances protein yield of a rationally-designed agonist antibody fragment in E-coli Academic Article
A stereospecific colorimetric assay for (S,S)-adenosylmethionine quantification based on thiopurine methyltransferase-catalyzed thiol methylation Academic Article
A stilbene that binds selectively to transthyretin in cells and remains dark until it undergoes a chemoselective reaction to create a bright blue fluorescent conjugate Academic Article
A stochastic Markov chain model to describe lung cancer growth and metastasis Academic Article
A strategy for cloning the hereditary hemochromatosis gene Academic Article
A strategy for probing the function of noncoding RNAs finds a repressor of NFAT Academic Article
A strategy to profile prime and non-prime proteolytic substrate specificity Academic Article
A streamlined platform for high-content functional proteomics of primary human specimens Academic Article
A stress response pathway regulates DNA damage through beta(2)-adrenoreceptors and beta-arrestin-1 Academic Article
A structural analysis of m protein in coronavirus assembly and morphology Academic Article
A structural change in the kinesin motor protein that drives motility Academic Article
A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine Academic Article
A structural framework for deciphering the link between I-A(g7) and autoimmune diabetes Academic Article
A structural hypothesis for bh4 responsiveness in patients with mild forms of hyperphenylalaninaemia and phenylketonuria Academic Article
A structural model for the prostate disease marker, human prostate-specific antigen Academic Article
A structural role of histidine 15 in human glutathione transferase M1-1, an amino acid residue conserved in class Mu enzymes Academic Article
A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union Academic Article
A structure-based approach to a synthetic vaccine for hiv-1 Academic Article
A structure-guided approach to creating covalent FGFR inhibitors Academic Article
A study of genes that may modulate the expression of hereditary hemochromatosis: Transferrin receptor-1, ferroportin, ceruloplasmin, ferritin light and heavy chains, iron regulatory proteins (irp)-1 and-2, and hepcidin Academic Article
A study of the specificity of the direct binding between bacteria and HLA antigens Academic Article
A subgroup-specific antigenic site in the G protein of respiratory syncytial virus forms a disulfide-bonded loop Academic Article
A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity Academic Article
A suite of activity-based probes for human cytochrome P450 enzymes Academic Article
A sulfilimine bond identified in collagen IV Academic Article
A superfolding Spinach2 reveals the dynamic nature of trinucleotide repeat-containing RNA Academic Article
A surface-modified sperm sorting device with long-term stability Academic Article
A survey of ancient conserved non-coding elements in the PAX6 locus reveals a landscape of interdigitated cis-regulatory archipelagos Academic Article
A survey of the anti-apoptotic Bcl-2 subfamily expression in cancer types provides a platform to predict the efficacy of Bcl-2 antagonists in cancer therapy Academic Article
A suspenseful game of 'hide and seek' between virus and host Academic Article
A syndrome of asymmetric limb weakness with motor conduction block Academic Article
A synthetic peptide defines a serologic IgA response to a human papillomavirus-encoded nuclear antigen expressed in virus-carrying cervical neoplasia Academic Article
A synthetic peptide mimic of plasma apolipoprotein-e that binds the ldl receptor Academic Article
A synthetic small molecule that induces neuronal differentiation of adult hippocampal neural progenitor cells Academic Article
A synthetic tlr4 antagonist has anti-inflammatory effects in two murine models of inflammatory bowel disease Academic Article
A system-wide investigation of the dynamics of Wnt signaling reveals novel phases of transcriptional regulation Academic Article
A systematic approach to understand the mechanism of action of the bisthiazolium compound T4 on the human malaria parasite, Plasmodium falciparum Academic Article
A systematic family-wide investigation reveals that ~30% of mammalian PDZ domains engage in PDZ-PDZ interactions Academic Article
A systematic genomewide linkage study in 353 sib pairs with schizophrenia Academic Article
A systems approach identifies essential FOXO3 functions at key steps of terminal rrythropoiesis Academic Article
A systems-based analysis of plasmodium vivax lifecycle transcription from human to mosquito Academic Article
A target within the target: probing cruzain's P1' site to define structural determinants for the Chagas' disease protease Academic Article
A telephone-based intervention for increasing the use of osteoporosis medication: a randomized controlled trial Academic Article
A telomere-dependent DNA damage checkpoint induced by prolonged mitotic arrest Academic Article
A therapeutic uricase with reduced immunogenicity risk and improved development properties Academic Article
A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions Academic Article
A tipping point for mistranslation and disease Academic Article
A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen Academic Article
A toxic RNA catalyzes the in cellulo synthesis of its own inhibitor Academic Article
A transgenic mouse model for measles virus infection of the brain Academic Article
A transgenic mouse model of the chronic hepatitis B surface antigen carrier state Academic Article
A translational approach to novel medication development for protracted abstinence Academic Article
A trojan horse with a sweet tooth Academic Article
A tumor necrosis factor (TNF) receptor-IgG heavy chain chimeric protein as a bivalent antagonist of TNF activity Academic Article
A two-allele polymorphism in protein C inhibitor with varying frequencies in different ethnic populations Academic Article
A two-antibody pan-ebolavirus cocktail confers broad therapeutic protection in ferrets and nonhuman primates Academic Article
A two-hit mechanism for pre-mitotic arrest of cancer cell proliferation by a polyamide-alkylator conjugate Academic Article
A two-segment model for thin filament architecture in skeletal muscle Academic Article
A type 2b von Willebrand disease mutation (Ile546 -> Val) associated with an unusual phenotype Academic Article
A tyrosine-rich region in the N terminus of CCR5 is important for human immunodeficiency virus type 1 entry and mediates an association between gp120 and CCR5 Academic Article
A tyrosine-sulfated CCR5-mimetic peptide promotes conformational transitions in the HIV-1 envelope glycoprotein Academic Article
A tyrosine-sulfated peptide based on the N terminus of CCR5 interacts with a CD4-enhanced epitope of the HIV-1 gp120 envelope glycoprotein and inhibits HIV-1 entry Academic Article
A tyrosine-sulfated peptide derived from the heavy-chain CDR3 region of an HIV-1-neutralizing antibody binds gp120 and inhibits HIV-1 infection Academic Article
A unified theory of prion propagation Academic Article
A unique and conserved neutralization epitope in H5N1 influenza viruses identified by an antibody against the A/Goose/Guangdong/1/96 hemagglutinin Academic Article
A unique class of duocarmycin and CC-1065 analogues subject to reductive activation Academic Article
A unique recognition site mediates the interaction of fibrinogen with the leukocyte integrin mac-1 (cd11b cd18) Academic Article
A unique sorting nexin regulates trafficking of potassium channels via a PDZ domain interaction Academic Article
A universal approach to the expression of human and rabbit cytochrome P450s of the 2C subfamily in Escherichia coli Academic Article
A vaccine for hiv type 1: The antibody perspective Academic Article
A validated assay by liquid chromatography-tandem mass spectrometry for the simultaneous quantification of elvitegravir and rilpivirine in HIV positive patients Academic Article
A variable cytoplasmic domain segment is necessary for γ-protocadherin trafficking and tubulation in the endosome/lysosome pathway Academic Article
A variable light domain fluorogen activating protein homodimerizes to activate dimethylindole red Academic Article
A variant of the gene encoding leukotriene a4 hydrolase confers ethnicity-specific risk of myocardial infarction Academic Article
A virocidal amphipathic α-helical peptide that inhibits hepatitis C virus infection in vitro Academic Article
A weighted polygenic risk score using 14 known susceptibility variants to estimate risk and age onset of psoriasis in han chinese Academic Article
A whole-genome association study of major determinants for host control of HIV-1 Academic Article
A yoga-based exercise program to reduce the risk of falls in seniors: a pilot and feasibility study Academic Article
A zebrafish genetic screen identifies neuromedin U as a regulator of sleep/wake states Academic Article
A zinc-finger transcriptional activator designed to interact with the gamma-globin gene promoters enhances fetal hemoglobin production in primary human adult erythroblasts Academic Article
A20 regulates canonical wnt-signaling through an interaction with RIPK4 Academic Article
A20 restricts wnt signaling in intestinal epithelial cells and suppresses colon carcinogenesis Academic Article
AAVrh.10-mediated expression of an anti-cocaine antibody mediates persistent passive immunization that suppresses cocaine-induced behavior Academic Article
ABHD12 controls brain lysophosphatidylserine pathways that are deregulated in a murine model of the neurodegenerative disease PHARC Academic Article
ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia Academic Article
ADCY5-related dyskinesia: Broader spectrum and genotype-phenotype correlations Academic Article
ADH1C*2 allele is associated with alcohol dependence and elevated liver enzymes in Trinidad and Tobago Academic Article
ADME pathway approach for pharmacogenetic studies of anti-HIV therapy Academic Article
ADME pharmacogenetics: investigation of the pharmacokinetics of the antiretroviral agent lopinavir coformulated with ritonavir Academic Article
AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation Academic Article
AG10 inhibits amyloidogenesis and cellular toxicity of the familial amyloid cardiomyopathy-associated V122I transthyretin Academic Article
AIDS-related dementia and calcium homeostasis Academic Article
AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs Academic Article
ALDH1 as a functional marker of cancer stem and progenitor cells Academic Article
ALS mutants of human superoxide dismutase form fibrous aggregates via framework destabilization Academic Article
AMPK at the crossroads of circadian clocks and metabolism Academic Article
AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation Academic Article
APC16 is a conserved subunit of the anaphase-promoting complex/cyclosome Academic Article
ARC15105 is a potent antagonist of von Willebrand factor mediated platelet activation and adhesion Academic Article
ASGCT and JSGT joint position statement on human genomic editing Academic Article
ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1 Academic Article
ASPP2 links the apical lateral polarity complex to the regulation of YAP activity in epithelial cells Academic Article
AST/ASTS workshop on increasing organ donation in the united states: creating an "arc of change" from removing disincentives to testing incentives Academic Article
ATF6 activation reduces the secretion and extracellular aggregation of destabilized variants of an amyloidogenic protein Academic Article
ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1 Academic Article
ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response Academic Article
ATM-dependent phosphorylation of MEF2D promotes neuronal survival after DNA damage Academic Article
ATP and the core "alpha-crystallin" domain of the small heat-shock protein alpha B-crystallin Academic Article
ATP-competitive, marine derived natural products that target the DEAD box helicase, eIF4A Academic Article
ATP-dependent chromatin remodeling enzymes: two heads are not better, just different Academic Article
ATP-directed capture of bioactive herbal-based medicine on human tRNA synthetase Academic Article
ATP-sensitive potassium channel (K-ATP)-dependent regulation of cardiotropic viral infections Academic Article
Abasic site recognition by two apurinic/apyrimidinic endonuclease families in DNA base excision repair: The 3 ' ends justify the means Academic Article
Abciximab (ReoPro) removal during cardiopulmonary bypass with a hemoconcentrator Academic Article
Abciximab and bleeding during coronary surgery: Results from the epilog and epistent trials Academic Article
Abciximab as adjunctive therapy to reperfusion in acute st-segment elevation myocardial infarction - a meta-analysis of randomized trials Academic Article
Abciximab reduces mortality in diabetics following percutaneous coronary intervention Academic Article
Abciximab suppresses the rise in levels of circulating inflammatory markers after percutaneous coronary revascularization Academic Article
Abciximab survival advantage following percutaneous coronary intervention is predicted by clinical risk profile Academic Article
Abciximab therapy and unplanned coronary stent deployment - favorable effects on stent use, clinical outcomes, and bleeding complications Academic Article
Abciximab-facilitated percutaneous coronary intervention and long-term survival - a prospective single-center registry Academic Article
Abenzyl 10-formyl-trideazafolic acid (abenzyl 10-formyl-TDAF): an effective inhibitor of glycinamide ribonucleotide transformylase Academic Article
Aberrant RNA splicing in sporadic amyotrophic lateral sclerosis Academic Article
Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness Academic Article
Aberrant expression of fetal RNA-binding protein p62 in liver cancer and liver cirrhosis Academic Article
Aberrant immunoglobulin-synthesis in light chain amyloidosis - free light chain and light chain fragment production by human-bone marrow-cells in short-term tissue-culture Academic Article
Aberrant multimeric structure of von Willebrand factor in a new variant of von Willebrand's disease (type IIC) Academic Article
Aberrant myofibril assembly in tropomodulin1 null mice leads to aborted heart development and embryonic lethality Academic Article
Aberrant protein S-nitrosylation contributes to the pathophysiology of neurodegenerative diseases Academic Article
Aberrant protein S-nitrosylation in neurodegenerative diseases Academic Article
Aberrant, persistent inclusion into lipid rafts limits the tumorigenic function of membrane type-1 matrix metalloproteinase in malignant cells Academic Article
Abeta localization in abnormal endosomes: Association with earliest Abeta elevations in AD and down syndrome Academic Article
Abl oncogene expression in non-hodgkin lymphomas: Correlation to histological differentiation and clinical status Academic Article
Ablating adenovirus type 5 fiber-car binding and hi loop insertion of the sigyplp peptide generate an endothelial cell-selective adenovirus Academic Article
Abnormal auditory n100 amplitude: A heritable endophenotype in first-degree relatives of schizophrenia probands Academic Article
Abnormal expression of plasminogen activator inhibitors in patients with gestational trophoblastic disease Academic Article
Abnormal expression of type 1 plasminogen activator inhibitor and tissue factor in severe preeclampsia Academic Article
Abnormal immunoglobulin synthesis in monoclonal immunoglobulin light chain and light and heavy chain deposition disease Academic Article
Abnormal tau induces cognitive impairment through two different mechanisms: synaptic dysfunction and neuronal loss Academic Article
Abnormalities in the fibrinolytic system of the vascular wall associated with atherosclerosis Academic Article
Abnormalities of plasma cytokines and spleen in senile APP/PS1/Tau transgenic mouse model Academic Article
Abnormalities of pulmonary vascular dynamics and inflammation in early progressive systemic-sclerosis Academic Article
Abrupt closure - the caveat-i experience Academic Article
Abrupt vessel closure after directional coronary atherectomy Academic Article
Abrupt vessel closure complicating coronary angioplasty - clinical, angiographic and therapeutic profile Academic Article
Absence of G(i) proteins in the Sf9 insect cell. Characterization of the uncoupled recombinant N-formyl peptide receptor Academic Article
Absence of binding activity of neuron-restrictive silencer factor is necessary, but not sufficient for transcription of NMDA receptor subunit type 1 in neuronal cells Academic Article
Absence of increased in-hospital complications with reused balloon catheters Academic Article
Absence of lymphotoxic antibodies in patients with Yersinia-induced arthritis, Reiter syndrome and ankylosing-spondylitis Academic Article
Absence of nephritogenic gbm antigen(s) in some patients with hereditary nephritis Academic Article
Absence of specific mucosal antibody responses in hiv-exposed uninfected sex workers from the gambia Academic Article
Abundant expression of apoprotein-e by macrophages in human and rabbit atherosclerotic lesions Academic Article
Academia-industry symbiosis in organic chemistry Academic Article
Academic cross-fertilization by public screening yields a remarkable class of protein phosphatase methylesterase-1 inhibitors Academic Article
Acamprosate Academic Article
Acamprosate and naltrexone treatment for alcohol dependence: an evidence-based risk-benefits assessment Academic Article
Acamprosate for alcohol dependence: A sex-specific meta-analysis based on individual patient data Academic Article
Acamprosate in the treatment of alcohol dependence Academic Article
Acamprosate in the treatment of alcohol dependence: clinical and economic considerations Academic Article
Acamprosate, alcoholism, and abstinence Academic Article
Acamprosate: a prototypic neuromodulator in the treatment of alcohol dependence Academic Article
Accelerated plasminogen-activator dose regimens for coronary thrombolysis Academic Article
Accelerating next-generation vaccine development for global disease prevention Academic Article
Acceptability of the use of motivational interviewing to reduce underage drinking in a Native American community Academic Article
Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gpl120 is sterically restricted on primary human immunodeficiency virus type 1 Academic Article
Access roads for RAG-ged terrains: Control of T cell receptor gene rearrangement at multiple levels Academic Article
Accessibility of nuclear chromatin by DNA binding polyamides Academic Article
Accessory genes confer a high replication rate to virulent feline immunodeficiency virus Academic Article
Accessory mutations maintain stability in drug-resistant HIV-1 protease Academic Article
Accommodating pathway information in expression quantitative trait locus analysis Academic Article
According to GOSPEL: filling in the GAP(DH) of NO-mediated neurotoxicity Academic Article
Accumulation of cyclin e is not a prerequisite for passage through the restriction point Academic Article
Accuracy of CT-based measurements of glenoid version for total shoulder arthroplasty Academic Article
Accuracy of haplotype frequency estimation for biallelic loci, via the expectation-maximization algorithm for unphased diploid genotype data Academic Article
Accurate detection and genotyping of snps utilizing population sequencing data Academic Article
Accurate prediction of deleterious protein kinase polymorphisms Academic Article
Acetylation of histone-like proteins of adenovirus type-5 Academic Article
Acid beta-galactosidase - a developmentally-regulated marker of endocrine cell precursors in the human fetal pancreas Academic Article
Acitretin in psoriasis: An overview of adverse effects Academic Article
Acoustically detectable cellular-level lung injury induced by fluid mechanical stresses in microfluidic airway systems Academic Article
Acquired abnormalities of von Willebrand factor: facts to consider in patients with unexpected bleeding Academic Article
Acquired congenital heart block. Pattern of maternal antibody response to biochemically defined antigens of the SSA/Ro-SSB/La system in neonatal lupus Academic Article
Acquired resistance to cisplatin and doxorubicin in a small cell lung cancer cell line is correlated to elevated expression of glutathione-linked detoxification enzymes Academic Article
Acquired von Willebrand's disease in the myeloproliferative syndrome Academic Article
Actin assembly plays a variable, but not obligatory role in receptor-mediated endocytosis in mammalian cells Academic Article
Actinopolysporins a-c and tubercidin as a pdcd4 stabilizer from the halophilic actinomycete actinopolyspora erythraea yim 90600 Academic Article
Action of RORs and their ligands in (patho)physiology Academic Article
Actions of acute and chronic ethanol on presynaptic terminals Academic Article
Actions of redox-related congeners of nitric oxide at the NMDA receptor Academic Article
Activated integrin alpha v beta 3 cooperates with metalloproteinase MMP-9 in regulating migration of metastatic breast cancer cells Academic Article
Activated partial thromboplastin time and outcome after thrombolytic therapy for acute myocardial infarction: Results for the gusto-i trial Academic Article
Activated platelet-T-cell conjugates in peripheral blood of patients with HIV infection: coupling coagulation/inflammation and T cells Academic Article
Activated protein C Academic Article
Activated protein C alters cytosolic calcium flux in human brain endothelium via binding to endothelial protein C receptor and activation of protease activated receptor-1 Academic Article
Activated protein C and inflammation in human myocardium after heart surgery Academic Article
Activated protein C and ischemic stroke Academic Article
Activated protein C in the cardioplegic solution on a porcine model of coronary ischemia-reperfusion has deleterious hemodynamic effects Academic Article
Activated protein C inhibits neutrophil extracellular trap formation in vitro and activation in vivo Academic Article
Activated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signaling in U937 cells Academic Article
Activated protein C mutant with minimal anticoagulant activity, normal cytoprotective activity, and preservation of thrombin activable fibrinolysis inhibitor-dependent cytoprotective functions Academic Article
Activated protein C plasma levels in the fasting and postprandial states among patients with previous unprovoked venous thromboembolism Academic Article
Activated protein C reduces graft neutrophil activation in clinical renal transplantation Academic Article
Activated protein C resistance caused by Arg506Gln mutation in factor Va Academic Article
Activated protein C resistance in ischemic stroke not due to factor V arginine(506)->glutamine mutation Academic Article
Activated protein C resistance: What have we learned now that the dust has settled? Academic Article
Activated protein C resistance: molecular mechanisms Academic Article
Activated protein C resistance: molecular mechanisms based on studies using purified Gln506-factor V Academic Article
Activated protein C variants with normal cytoprotective but reduced anticoagulant activity Academic Article
Activated protein C-dependent and -independent anticoagulant activities of protein S have different structural requirements Academic Article
Activated protein C: Potential therapy for severe sepsis, thrombosis, and stroke Academic Article
Activated protein C: biased for translation Academic Article
Activated protein c blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective Academic Article
Activated protein c correlates inversely with thrombin levels in resting healthy individuals Academic Article
Activated protein c in sepsis: The promise of nonanticoagulant activated protein c Academic Article
Activated protein c up-regulates procoagulant tissue factor activity on endothelial cells by shedding the tfpi kunitz 1 domain Academic Article
Activated protein c-cleaved protease activated receptor-1 is retained on the endothelial cell surface even in the presence of thrombin Academic Article
Activating pleiotropic receptors to kill cancer cells Academic Article
Activating transcription factor 4 increases chemotherapeutics resistance of human hepatocellular carcinoma Academic Article
Activation and complexation of protein C and cleavage and decrease of protein S in plasma of patients with intravascular coagulation Academic Article
Activation and function of gamma-delta t-cells Academic Article
Activation of AMP-activated protein kinase revealed by hydrogen/deuterium exchange mass spectrometry Academic Article
Activation of CD74 inhibits migration of human mesenchymal stem cells Academic Article
Activation of Hageman factor by proteases released during antigen challenge of human lung Academic Article
Activation of Hageman factor in solid and fluid phases. A critical role of kallikrein Academic Article
Activation of JNK3 alpha 1 requires both MKK4 and MKK7: Kinetic characterization of in vitro phosphorylated JNK3 alpha 1 Academic Article
Activation of MPF in fission yeast Academic Article
Activation of angiogenic signaling pathways by two human tRNA synthetases Academic Article
Activation of c-myc gene expression by tumor-derived p53 mutants requires a discrete c-terminal domain Academic Article
Activation of c1 by monoclonal-antibodies directed against c1q Academic Article
Activation of cancer cell migration and invasion by ectopic synthesis of coagulation factor vii Academic Article
Activation of coagulation and angiogenesis in cancer - immunohistochemical localization in situ of clotting proteins and vascular endothelial growth factor in human cancer Academic Article
Activation of cyclin e/cdk2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin e Academic Article
Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes Academic Article
Activation of endothelial cell protease activated receptor 1 by the protein c pathway Academic Article
Activation of human complement by human lymphoid cells sensitized with histocompatibility alloantisera Academic Article
Activation of human effector cells by a tumor reactive recombinant anti-ganglioside gd(2) interleukin-2 fusion protein (ch14.18-il2) Academic Article
Activation of human factor-VII in plasma and in purified systems - roles of activated factor-IX, kallikrein, and activated factor-XII Academic Article
Activation of human peripheral-blood mononuclear-cells by anti-t3 - killing of tumor target-cells coated with anti-target-anti-t3 conjugates Academic Article
Activation of matrix metalloproteinase-9 (mmp-9) via a converging plasmin/stromelysin-1 cascade enhances tumor cell invasion Academic Article
Activation of methotrexate-alpha-alanine by carboxypeptidase-A monoclonal-antibody conjugate Academic Article
Activation of mitogen-activated protein kinases and p90 ribosomal s6 kinase in failing human hearts with dilated cardiomyopathy Academic Article
Activation of neutrophils by N-formyl chemotactic peptides Academic Article
Activation of nuclear receptor coactivator PGC-1 alpha by arginine methylation Academic Article
Activation of p38 in stimulated human neutrophils: Phosphorylation of the oxidase component p47(phox) by p38 and erk but not by jnk Academic Article
Activation of platelets in blood perfusing angioplasty-damaged coronary arteries. Flow cytometric detection Academic Article
Activation of preexisting t cell clones by targeted interleukin 2 therapy Academic Article
Activation of pro-uPA is critical for initial escape from the primary tumor and hematogenous dissemination of human carcinoma cells Academic Article
Activation of proMMP-9 by a plasmin/MMP-3 cascade in a tumor cell model. Regulation by tissue inhibitors of metalloproteinases Academic Article
Activation of protein C and hemodynamic recovery after coronary artery bypass surgery Academic Article
Activation of protein C during reperfusion in clinical liver transplantation Academic Article
Activation of rabbit tlr9 by different cpg-odn optimized for mouse and human tlr9 Academic Article
Activation of resting lymphocytes-T by anti-CD3 (T3) antibodies in the absence of monocytes Academic Article
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Antibody-dependent cell-mediated cytotoxicity effector-enhanced EphA2 agonist monoclonal antibody demonstrates potent activity against human tumors Academic Article
Antibody-dependent cellular cytotoxicity against murine leukemia viral-antigens - studies with human lymphoblastoid cell lines and human peripheral lymphocytes as effector cells comparing rabbit, goat, and mouse antisera Academic Article
Antibody-dependent lymphocytotoxicity induced by immunoglobulin-g from hodgkins-disease splenic lymphocytes Academic Article
Antibody-drug conjugate library prepared by scanning insertion of the aldehyde tag into IgG1 constant regions Academic Article
Antibody-drug conjugates (ADCs) derived from interchain cysteine cross-linking demonstrate improved homogeneity and other pharmacological properties over conventional heterogeneous ADCs Academic Article
Antibody-il-12 fusion proteins are effective in scid mouse models of prostate and colon carcinoma metastases Academic Article
Antibody-independent activation of the alternative complement pathway by measles virus-infected cells Academic Article
Antibody-induced redistribution of measles-virus antigens on cell-surface Academic Article
Antibody-interleukin 2 fusion proteins: A new approach to cancer therapy Academic Article
Antibody-mediated neutralization of ebola virus can occur by two distinct mechanisms Academic Article
Antibody-recruiting molecules: an emerging paradigm for engaging immune function in treating human disease Academic Article
Antibody-targeted interleukin-2 stimulates t-cell killing of autologous tumor-cells Academic Article
Anticancer properties of distinct antimalarial drug classes Academic Article
Anticholinergic potency of psychoactive drugs in human and rat cerebral cortex and striatum Academic Article
Anticoagulant dysfunction of human Arg352Trp-activated protein C caused by defective factor Va inactivation Academic Article
Anticoagulant protein-C pathway defective in majority of thrombophilic patients Academic Article
Anticoagulant response to activated protein-C- method validation and assay comparison Academic Article
Anticoagulant synergism of heparin and activated protein C in vitro - role of a novel anticoagulant mechanism of heparin, enhancement of inactivation of factor V by activated protein C Academic Article
Anticodon G recognition by tRNA synthetases mimics the tRNA core Academic Article
Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor Academic Article
Anticytokine gene therapy of autoimmune diseases Academic Article
Anticytoplasmic antibodies in antinuclear antibody-negative lupus erythematosus. Correlation with clinical course Academic Article
Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation Academic Article
Antidiabetic phospholipid-nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation Academic Article
Antifungal azoles: structural insights into undesired tight binding to cholesterol-metabolizing CYP46A1 Academic Article
Antigen compartmentation and t helper cell tolerance induction Academic Article
Antigen delivery to macrophages using liposomal nanoparticles targeting sialoadhesin/cd169 Academic Article
Antigen processing by autoreactive B cells promotes determinant spreading Academic Article
Antigen processing patterns determine GAD65-specific regulation vs. pathogenesis Academic Article
Antigen receptor selection by editing or downregulation of v(d)j recombination Academic Article
Antigen recognition by variable lymphocyte receptors Academic Article
Antigen selection from an HIV-1 immune antibody library displayed on yeast yields many novel antibodies compared to selection from the same library displayed on phage Academic Article
Antigen-induced conformational-changes in antibodies - a problem for structural prediction and design Academic Article
Antigen-processing and presentation Academic Article
Antigen-specific immunity - th cell-dependent a cell responses Academic Article
Antigen-specific memory B cell development Academic Article
Antigen-specific regulation of t cell-mediated cytokine production Academic Article
Antigenic analysis of the 2nd extra-cellular loop of the human beta-adrenergic receptors Academic Article
Antigenic and immunogenic study of membrane-proximal external region-grafted gp120 antigens by a DNA prime-protein boost immunization strategy Academic Article
Antigenic and immunologic characterization of an allogeneic colon carcinoma vaccine Academic Article
Antigenic expression of human-melanoma cells in serum-free medium Academic Article
Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis Academic Article
Antigenic mimicry of the hiv envelope by aids-associated pathogens Academic Article
Antigenic modulation - a mechanism of viral persistence Academic Article
Antigenic modulation induced by monoclonal-antibodies - antibodies to measles-virus hemagglutinin alters expression of other viral polypeptides in infected-cells Academic Article
Antigenic peptides Academic Article
Antigenic stimulus in human transplantation Academic Article
Antigens associated with a human-lung adenocarcinoma defined by monoclonal-antibodies Academic Article
Antigens associated with human squamous-cell lung-carcinoma defined by murine monoclonal-antibodies Academic Article
Antihistone antibodies in idiopathic and drug-induced lupus recognize distinct intrahistone regions Academic Article
Antihypertensive and hypotensive effects of atrial natriuretic factor in men Academic Article
Antiidiotype and antihormone receptor antibodies Academic Article
Antiidiotypic antibodies against hormone and neurotransmitter receptors Academic Article
Antimalarial activity of 10-alkyl/aryl esters and -aminoethylethers of artemisinin Academic Article
Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance Academic Article
Antimalarials in development in 2014 Academic Article
Antimitochondrial autoantibodies in primary biliary-cirrhosis recognize cross-reactive epitope(s) on protein-x and dihydrolipoamide acetyltransferase of pyruvate-dehydrogenase complex Academic Article
Antimitotic agents of natural origin Academic Article
Antimycotic ciclopirox olamine in the diabetic environment promotes angiogenesis and enhances wound healing Academic Article
Antimyenteric neuronal antibodies in scleroderma Academic Article
Antinuclear antibodies (ANAs): diagnostically specific immune markers and clues toward the understanding of systemic autoimmunity Academic Article
Antinuclear antibodies and nuclear antigens in rheumatoid synovial fluids Academic Article
Antinuclear antibodies defining autoimmunity pathways Academic Article
Antinuclear antibodies in Coombs-positive acquired hemolytic anemia Academic Article
Antinuclear antibodies in diagnosis and management Academic Article
Antinuclear antibodies in infectious mononucleosis Academic Article
Antinuclear antibodies in scleroderma Academic Article
Antinuclear antibodies: diagnostic markers and clues to the basis of systemic autoimmunity Academic Article
Antinuclear antibodies: diagnostic markers for autoimmune diseases and probes for cell biology Academic Article
Antinuclear autoantibodies in prostate cancer: immunity to LEDGF/p75, a survival protein highly expressed in prostate tumors and cleaved during apoptosis Academic Article
Antinuclear autoantibodies in women with silicone breast implants Academic Article
Antinuclear autoantibodies: probes for defining proteolytic events associated with apoptosis Academic Article
Antinuclear, antinucleolar, and anticytoplasmic antibodies in patients with malignant melanoma Academic Article
Antinucleolar antibodies in human sera Academic Article
Antiparasitic lethality of sulfonamidebenzamides in kinetoplastids Academic Article
Antiphospholipid antibodies are directed against epitopes of oxidized phospholipids - recognition of cardiolipin by monoclonal antibodies to epitopes of oxidized low density lipoprotein Academic Article
Antiphospholipid antibodies in systemic lupus-erythematosus - clinical and laboratory associations in 111 patients Academic Article
Antiplatelet agents in cardiology: the choice of therapy Academic Article
Antiplatelet and anticoagulant therapy in the secondary prevention of ischemic heart disease Academic Article
Antiplatelet and anticoagulant use after myocardial infarction Academic Article
Antiplatelet antibodies in chronic adult immune thrombocytopenic purpura: Assays and epitopes Academic Article
Antiplatelet antibodies in chronic immune thrombocytopenia and their role in platelet destruction and defective platelet production Academic Article
Antiplatelet medications and their indications in preventing and treating coronary thrombosis Academic Article
Antiproliferation activity of a small molecule repressor of liver receptor homolog 1 Academic Article
Antiproliferative effects of enediynes on aids-derived kaposis-sarcoma cells Academic Article
Antiretroviral activity and Vif sensitivity of rhesus macaque APOBEC3 proteins Academic Article
Antiretroviral drug resistance mutations in the reverse transcriptase gene of HIV-1 isolates from Northern Indian patients: a follow-up study Academic Article
Antiretroviral drug toxicity in relation to pharmacokinetics, metabolic profile and pharmacogenetics Academic Article
Antiretroviral treatment of adult HIV infection: 2010 recommendations of the International AIDS Society-USA panel Academic Article
Antiretroviral treatment of adult HIV infection: 2012 recommendations of the International Antiviral Society-USA panel Academic Article
Antiretroviral treatment of adult HIV infection: 2014 recommendations of the International Antiviral Society-USA Panel Academic Article
Antisaccade performance in schizophrenia patients, their first-degree biological relatives, and community comparison subjects: Data from the cogs study Academic Article
Antischistosomal versus antiandrogenic properties of aryl hydantoin Ro 13-3978 Academic Article
Antisense RNA complementary to 3' coding and noncoding sequences of creatine kinase is a potent inhibitor of translation in vivo Academic Article
Antisense RNA complementary to hepatitis B virus specifically inhibits viral replication Academic Article
Antisense RNA controls LRP1 sense transcript expression through interaction with a chromatin-associated protein, HMGB2 Academic Article
Antisense palmitoyl protein thioesterase 1 (PPT1) treatment inhibits PPT1 activity and increases cell death in LA-N-5 neuroblastoma cells Academic Article
Antisense treatment of viral-infection Academic Article
Antisense-mediated resistance to measles virus infection in hela cells Academic Article
Antistress action of a corticotropin-releasing factor antagonist on behavioral reactivity to stressors of varying type and intensity Academic Article
Antithrombotic activity of protein S infused without activated protein C in a baboon thrombosis model Academic Article
Antithrombotic therapy with intracoronary stenting Academic Article
Antitubular basement-membrane antibodies after renal-transplantation Academic Article
Antitubular basement-membrane antibodies in methicillin-associated interstitial nephritis Academic Article
Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase Academic Article
Antitumor activity of hu14.18-il2 in patients with relapsed/refractory neuroblastoma: A children's oncology group (cog) phase ii study Academic Article
Antitumor effects and mechanisms ofAZD4547on FGFR2-deregulated endometrial cancer cells Academic Article
Antitumor efficacy of 26-fluoroepothilone b against human prostate cancer xenografts Academic Article
Antiviral activity of a small-molecule inhibitor of arenavirus glycoprotein processing by the cellular site 1 protease Academic Article
Antiviral agent blocks breathing of the common cold virus Academic Article
Antiviral antibody reacting on the plasma membrane alters measles virus expression inside the cell Academic Article
Antiviral antibody responses: the two extremes of a wide spectrum Academic Article
Antiviral antibody-responses in patients with renal-disease Academic Article
Antiviral cyclic D,L-α-peptides: Targeting a general biochemical pathway in virus infections Academic Article
Antiviral pressure exerted by hiv-1-specific cytotoxic t lymphocytes (ctls) during primary infection demonstrated by rapid selection of ctl escape virus Academic Article
Antiviral stilbene 1,2-diamines prevent initiation of hepatitis C virus RNA replication at the outset of infection Academic Article
Anxiogenic-like effects limit rewarding effects of cocaine in balb/cbyj mice Academic Article
Aortocoronary saphenous vein graft disease - pathogenesis, predisposition, and prevention Academic Article
Ap-2/eps15 interaction is required for receptor-mediated endocytosis Academic Article
Apaf-1 is a transcriptional target for E2F and p53 Academic Article
Apelin, the natural ligand of the orphan seven-transmembrane receptor APJ, inhibits human immunodeficiency virus type 1 entry Academic Article
Apical topography and modulation of ICAM-1 expression on activated endothelium Academic Article
Apo-human carbonic anhydrase II revisited: implications of the loss of a metal in protein structure, stability, and solvent network Academic Article
ApoE4 decreases spine density and dendritic complexity in cortical neurons in vivo Academic Article
Apolipoprotein (apo) E inhibits the capacity of monosodium urate crystals to stimulate neutrophils. Characterization of intraarticular apo E and demonstration of apo E binding to urate crystals in vivo Academic Article
Apolipoprotein E receptor 2 mediates activated protein C-induced endothelial Akt activation and endothelial barrier stabilization Academic Article
Apolipoprotein a-i structural organization in high-density lipoproteins isolated from human plasma Academic Article
Apolipoprotein a-ii inhibits high density lipoprotein remodeling and lipid-poor apolipoprotein a-i formation Academic Article
Apolipoprotein d levels are elevated in prefrontal cortex of subjects with alzheimer's disease: No relation to apolipoprotein e expression or genotype Academic Article
Apolipoprotein d modulates arachidonic acid signaling in cultured cells: Implications for psychiatric disorders Academic Article
Apolipoprotein d mrna expression is elevated in pdapp transgenic mice Academic Article
Apolipoprotein e and atherosclerosis Academic Article
Apolipoprotein-b allotype-mb191 and allotype-mb192 in subjects with coronary-artery disease and hypercholesterolemia Academic Article
Apolipoprotein-e is a biologically-active constituent of the normal immunoregulatory lipoprotein, ldl-in Academic Article
Apoprotein-e-rich high-density lipoproteins inhibit ovarian androgen synthesis Academic Article
Apoptosis in rheumatic disease Academic Article
Apoptosis induced by HIV infection in H9 T cells is blocked by ICE-family protease inhibition but not by a Fas(CD95) antagonist Academic Article
Apoptosis signaling pathway in t cells is composed of ice/ced-3 family proteases and map kinase kinase 6b Academic Article
Apoptosis-inducing factor mediates microglial and neuronal apoptosis caused by pneumococcus Academic Article
Apoptotic tumor cells induce il-27 release from human dcs to activate treg cells that express cd69 and attenuate cytotoxicity Academic Article
App processing, A beta-amyloidogenesis, and the pathogenesis of alzheimers-disease Academic Article
Apparent loss-of-function mutant GPCRs revealed as constitutively desensitized receptors Academic Article
Applicability of percutaneous trans-luminal coronary angioplasty to patients with recombinant tissue plasminogen-activator mediated thrombolysis Academic Article
Application of a continuous regression model of restenosis to saphenous vein grafts after successful percutaneous transluminal coronary angioplasty or directional coronary atherectomy Academic Article
Application of a low cost array-based technique - TAB-Array - for quantifying and mapping both 5mC and 5hmC at single base resolution in human pluripotent stem cells Academic Article
Application of a multiprobe RNase protection assay and junctional sequences to define V beta gene diversity in Sezary-syndrome Academic Article
Application of activity-based protein profiling to study enzyme function in adipocytes Academic Article
Application of affinity selection/mass spectrometry to determine the structural isomer of parnafungins responsible for binding polyadenosine polymerase Academic Article
Application of beta-lactamase enzyme complementation to the high-throughput screening of toll-like receptor signaling inhibitors Academic Article
Application of genomics to toxicology research Academic Article
Application of mass spectrometry to study proteomics and interactomics in cystic fibrosis Academic Article
Application of microdroplet pcr for large-scale targeted bisulfite sequencing Academic Article
Application of microfluidic technologies to human assisted reproduction Academic Article
Application of parallel multiparametric cell-based FLIPR detection assays for the identification of modulators of the muscarinic acetylcholine receptor 4 (M-4) Academic Article
Application of solid-phase clq and raji cell radioimmune assays for detection of circulating immune-complexes in glomerulonephritis Academic Article
Application of strain-promoted azide-alkyne cycloaddition and tetrazine ligation to targeted Fc-drug conjugates Academic Article
Application of the murine anti-gd-2 antibody 14.Gd-2a for diagnosis and therapy of neuroblastoma Academic Article
Application of transcriptional and posttranscriptional reporter constructs to the analysis of tumor necrosis factor gene regulation Academic Article
Applications of beta-mixture models in bioinformatics Academic Article
Applications of laser-polarized (129)Xe to biomolecular assays Academic Article
Applications of two-dimensional infrared spectroscopy Academic Article
Applied systems biology and malaria Academic Article
Applying PET to broaden the diagnostic utility of the clinically validated CA19.9 serum biomarker for oncology Academic Article
Applying genomics to organ transplantation medicine in both discovery and validation of biomarkers Academic Article
Applying the new genomics to alcohol dependence Academic Article
Applying ⁸⁹Zr-transferrin to study the pharmacology of inhibitors to BET bromodomain containing proteins Academic Article
Approaches for isolation of biologically functional tumor-associated antigens Academic Article
Approaches for skeletal gene therapy Academic Article
Approaches to enhancing the retroviral transduction of human synoviocytes Academic Article
Approaches to validate and manipulate RNA targets with small molecules in cells Chapter
Approaching rational epitope vaccine design for hepatitis C virus with meta-server and multivalent scaffolding Academic Article
Apricoxib, a COX-2 inhibitor for the potential treatment of pain and cancer Academic Article
Aprotinin (trasylol) is a competitive inhibitor of activated protein-C Academic Article
Aptamer ARC19499 mediates a procoagulant hemostatic effect by inhibiting tissue factor pathway inhibitor Academic Article
Aptamer BAX499 mediates inhibition of tissue factor pathway inhibitor via interaction with multiple domains of the protein Academic Article
Aptamer selection by high-throughput sequencing and informatic analysis Academic Article
Aptamer-based multiplexed proteomic technology for biomarker discovery Academic Article
Aptamers and the RNA world, past and present Academic Article
Aptazyme-based riboswitches and logic gates in mammalian cells Academic Article
Apurinic/apyrimidinic endonuclease 1 alters estrogen receptor activity and estrogen-responsive gene expression Academic Article
Aqueous two-phase printing of cell-containing contractile collagen microgels Academic Article
Aqueous two-phase system patterning of detection antibody solutions for cross-reaction-free multiplex ELISA Academic Article
Aqueous two-phase system-mediated antibody micropatterning enables multiplexed immunostaining of cell monolayers and tissues Academic Article
Architecture and metamorphosis Academic Article
Architecture of cannabinoid signaling in mouse retina Academic Article
Architecture of cd1 proteins Academic Article
Are blastocyst aneuploidy rates different between fertile and infertile populations? Academic Article
Are external knee load and EMG measures accurate indicators of internal knee contact forces during gait? Academic Article
Are integrin alpha(2)beta(1), glycoprotein Ib and vWf levels correlated with their contributions to platelet adhesion on collagen under high-shear flow? Academic Article
Are viral-encoded microRNAs mediating latent HIV-1 infection? Academic Article
Are viral-encoded microRNAs mediating latent HIV-1 infection? Academic Article
Arenavirus extinction through lethal mutagenesis Academic Article
Arenavirus genetic diversity and its biological implications Academic Article
Arenavirus nucleoprotein targets interferon regulatory factor-activating kinase IKK epsilon Academic Article
Arenavirus nucleoproteins prevent activation of nuclear factor kappa b Academic Article
Arenavirus reverse genetics for vaccine development Academic Article
Arenavirus reverse genetics: New approaches for the investigation of arenavirus biology and development of antiviral strategies Academic Article
Arenaviruses i - the epidemiology, molecular and cell biology of arenaviruses - preface Academic Article
Arenaviruses: Genomic RNAs, transcription, and replication Academic Article
Arginine methylation of NIP45 modulates cytokine gene expression in effector T lymphocytes Academic Article
Arginine methylation of STAT1 modulates IFN alpha/beta-induced transcription Academic Article
Arginine methylation of recombinant murine fibrillarin by protein arginine methyltransferase Academic Article
Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification Academic Article
Arginine vasopressin, stress, and memory Academic Article
Arginyltransferase ATE1 catalyzes midchain arginylation of proteins at side chain carboxylates in vivo Academic Article
Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells Academic Article
Aromatic residues at the edge of the antibody combining site facilitate viral glycoprotein recognition through membrane interactions Academic Article
Aromatic residues in the C-terminal region of glutathione transferase A1-1 influence rate-determining steps in the catalytic mechanism Academic Article
Aromatic sulfonyl fluorides covalently kinetically stabilize transthyretin to prevent amyloidogenesis while affording a fluorescent conjugate Academic Article
Arrayed protein library technology for therapeutic biologic discovery Academic Article
Arrays of horizontally-oriented mini-reservoirs generate steady microfluidic flows for continuous perfusion cell culture and gradient generation Academic Article
Arrest of beta-amyloid fibril formation by a pentapeptide ligand Academic Article
Arresting cancer proliferation by small-molecule gene regulation Academic Article
Arterial plasma norepinephrine correlates to blood-pressure in middle-aged men with sustained essential-hypertension Academic Article
Arteriovenous blood metabolomics: a readout of intra-tissue metabostasis Academic Article
Arthritis gene therapy and its tortuous path into the clinic Academic Article
Arthritis gene therapy's first death Academic Article
Artifacts in measurement of blood pressure and lack of target organ involvement in the assessment of patients with treatment-resistant hypertension Academic Article
Artificial control of gene expression in mammalian cells by modulating RNA interference through aptamer-small molecule interaction Academic Article
Artificial hematopoietic stem cell niche: bioscaffolds to microfluidics to mathematical simulations Academic Article
Artificial intelligence versus clinicians: systematic review of design, reporting standards, and claims of deep learning studies Academic Article
Artificial ligand binding within the HIF2α PAS-B domain of the HIF2 transcription factor Academic Article
Artophagy: the art of autophagy--the Cvt pathway Academic Article
Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells Academic Article
Arylsulfonamide kcn1 inhibits in vivo glioma growth and interferes with hif signaling by disrupting hif-1 alpha interaction with cofactors p300/cbp Academic Article
Ascorbic acid enhances the effects of 6-hydroxydopamine and H2O2 on iron-dependent DNA strand breaks and related processes in the neuroblastoma cell line SK-N-SH Academic Article
Aspartylglycosaminuria in the Finnish population: identification of two point mutations in the heavy chain of glycoasparaginase Academic Article
Aspects of the molecular-structure of igg subclasses Academic Article
Aspirin and clopidogrel resistance: An emerging clinical entity Academic Article
Aspirin dose and six-month outcome after an acute coronary syndrome Academic Article
Aspirin dose for the prevention of cardiovascular disease: a systematic review Academic Article
Aspirin resistance and a single gene Academic Article
Aspirin to prevent cardiovascular disease: The association of aspirin dose and clopidogrel with thrombosis and bleeding Academic Article
Assay for i kappa b kinases using an in vivo biotinylated i kappa b protein substrate Academic Article
Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility Academic Article
Assay strategies for identification of therapeutic leads that target protein trafficking Academic Article
Assemblages: functional units formed by cellular phase separation Academic Article
Assembly and architecture of HIV Academic Article
Assembly and expression of an intrinsic factor-IX activator complex on the surface of cultured human endothelial-cells Academic Article
Assembly and intracellular transport of MHC class I and class II molecules Academic Article
Assembly and transport of MHC class II molecules Academic Article
Assembly and transport of major histocompatibility complex molecules Academic Article
Assembly of multi-tRNA synthetase complex via heterotetrameric glutathione transferase-homology domains Academic Article
Assembly of transcriptionally active 5S RNA gene chromatin in vitro Academic Article
Assembly with the NR1 subunit is required for surface expression of NR3A-containing NMDA receptors Academic Article
Assessing aspirin responsiveness in subjects with multiple risk factors for vascular disease with a rapid platelet function analyzer Academic Article
Assessing compound binding to the Eg5 motor domain using a thermal shift assay Academic Article
Assessing enzyme activities using stable isotope labeling and mass spectrometry Academic Article
Assessing information in t2-weighted mri scans from secondary progressive ms patients Academic Article
Assessing prion infectivity of human urine in sporadic Creutzfeldt-Jakob disease Academic Article
Assessing self-renewal and differentiation in human embryonic stem cell lines Academic Article
Assessing the function of human unc-93b in toll-like receptor signaling and major histocompatibility complex ii response Academic Article
Assessing the impact of population stratification on genetic association studies Academic Article
Assessing the optimal level of platelet inhibition with GPIIb/IIIa inhibitors in patients undergoing coronary intervention. Rationale and design of the GOLD study Academic Article
Assessing the risks associated with MRI in patients with a pacemaker or defibrillator Academic Article
Assessment of RNA carrier function in peptide amphiphiles derived from the HIV fusion peptide Academic Article
Assessment of coronary reperfusion after thrombolysis with a model combining myoglobin, creatine kinase-mb, and clinical variables Academic Article
Assessment of cortical bone with clinical and ultrashort echo time sequences Academic Article
Assessment of ionizable, zwitterionic oximes as reactivating antidotal agents for organophosphate exposure Academic Article
Assessment of multiple displacement amplification for polymorphism discovery and haplotype determination at a highly polymorphic locus, mc1r Academic Article
Assessment of reperfusion after thrombolytic therapy for myocardial-infarction Academic Article
Assessment of the red cell proteome of young patients with unexplained hemolytic anemia by two-dimensional differential in-gel electrophoresis (dige) Academic Article
Assessment of young men at risk for alcoholism with p300 from a visual-discrimination task Academic Article
Assignment and modeling of the Rev Response Element RNA bound to a Rev peptide using 13C-heteronuclear NMR Academic Article
Assignment of big map kinase (prkm7) to human chromosome 17 band p11.2 with somatic cell hybrids Academic Article
Assignment of death associated protein 3 (DAP3) to human chromosome 1q21 by in situ hybridization Academic Article
Assignment of human myocyte-specific enhancer binding factor 2C (hMEF2C) to human chromosome 5q14 and evidence that MEF2C is evolutionarily conserved Academic Article
Assignment of methylene proton resonances in NMR-spectra of embryonic and transformed-cells to plasma-membrane triglyceride Academic Article
Assignment of resonances in the h-1 nuclear-magnetic-resonance spectrum of the carbon-monoxide complex of human-hemoglobin alpha-chains Academic Article
Association and ancestry analysis of sequence variants in ADH and ALDH using alcohol-related phenotypes in a Native American community sample Academic Article
Association between a disrupted-in-schizophrenia 1 (disc1) single nucleotide polymorphism and schizophrenia in a combined scandinavian case-control sample Academic Article
Association between a genetic variant in the serotonin transporter gene (slc6a4) and suicidal behavior in patients with schizophrenia Academic Article
Association between admission white blood cell count and one-year mortality in patients with acute coronary syndromes Academic Article
Association between ck-mb elevation after percutaneous or surgical revascularization and three-year mortality Academic Article
Association between inflammatory biomarkers and platelet aggregation in patients under chronic clopidogrel treatment Academic Article
Association between methylenetetrahydrofolate reductase (mthfr) c677t polymorphism and age of onset in schizophrenia Academic Article
Association between minor elevations of creatine kinase-mb level and mortality in patients with acute coronary syndromes without st-segment elevation Academic Article
Association between mitochondrial DNA variations and alzheimer's disease in the adni cohort Academic Article
Association between myeloperoxidase levels and risk of coronary artery disease Academic Article
Association between nocturnal vagal tone and sleep depth, sleep quality, and fatigue in alcohol dependence Academic Article
Association between single nucleotide polymorphisms in the cannabinoid receptor gene (CNR1) and impulsivity in Southwest California Indians Academic Article
Association between single nucleotide polymorphisms in the mu opioid receptor gene (OPRM1) and self-reported responses to alcohol in American Indians Academic Article
Association between the nucleolus and the coiled body Academic Article
Association between thromboembolic events and the JAK2 V617F mutation in myeloproliferative neoplasms Academic Article
Association between traumatic brain injury and risk of posttraumatic stress disorder in active-duty Marines Academic Article
Association of ALDH1 promoter polymorphisms with alcohol-related phenotypes in Trinidad and Tobago Academic Article
Association of ALDH1 promoter polymorphisms with alcohol-related phenotypes in southwest California Indians Academic Article
Association of AR-V7 on circulating tumor cells as a treatment-specific biomarker with outcomes and survival in castration-resistant prostate cancer Academic Article
Association of Apo(a)isoform size with dyslipoproteinemia in male venous thrombosis patients Academic Article
Association of EEG alpha variants and alpha power with alcohol dependence in Mexican American young adults Academic Article
Association of Rgs7/Gβ5 complexes with Girk channels and GABAB receptors in hippocampal CA1 pyramidal neurons Academic Article
Association of alcohol dehydrogenase genes with alcohol-related phenotypes in a native american community sample Academic Article
Association of an isomeric species of carcinoembryonic antigen with neoplasia of gastrointestinal-tract Academic Article
Association of an rna polymerase-iii transcription factor with a ribonucleoprotein complex recognized by autoimmune sera Academic Article
Association of antibody to histone complex H2A-H2B with symptomatic procainamide-induced lupus Academic Article
Association of antinuclear and antinucleolar antibodies in progressive systemic sclerosis Academic Article
Association of beta(3)-adrenoceptor polymorphism with obesity and diabetes: Current status Academic Article
Association of common genetic variants in gpcpd1 with scaling of visual cortical surface area in humans Academic Article
Association of common genetic variation in the insulin/igf1 signaling pathway with human longevity Academic Article
Association of diabetes mellitus and glycemic control strategies with clinical outcomes after acute coronary syndromes Academic Article
Association of direct-to-consumer genome-wide disease risk estimates and self-reported disease Academic Article
Association of genetic variants in the hdl receptor, sr-b1, with abnormal lipids in women with coronary artery disease Academic Article
Association of genetic variants on 15q12 with cortical thickness and cognition in schizophrenia Academic Article
Association of height with outcomes in patients with acute myocardial infarction receiving reperfusion therapy Academic Article
Association of hl-a antigens and beta 2-microglobulin: Concepts and questions Academic Article
Association of human and bovine beta-2-microglobulins with detergent solubilized hla-a,b antigens Academic Article
Association of human cyclin-e with a periodic g(1)-s phase protein-kinase Academic Article
Association of low protein Z levels with ischemic stroke in young women Academic Article
Association of lupuslike anticoagulant and nonvasculitic cerebral infarction Academic Article
Association of mortality with years of education in patients with st-segment elevation myocardial infarction treated with fibrinolysis Academic Article
Association of p130(cas) with phosphatidylinositol-3-oh kinase mediates adenovirus cell entry Academic Article
Association of pharmacogenetic markers with premature discontinuation of first-line anti-HIV therapy: an observational cohort study Academic Article
Association of plasma apolipoproteins d with rbc membrane arachidonic acid levels in schizophrenia Academic Article
Association of race with complications and prognosis fohowing acute coronary syndromes Academic Article
Association of sets of alleles of genes encoding beta(3)-adrenoreceptor, uncoupling protein 1 and lipoprotein lipase with increased risk of metabolic complications in obesity Academic Article
Association of sporadic chondrocalcinosis with a-4-basepair g-to-a transition in the 5 '-untranslated region of ANKH that promotes enhanced expression of ANKH protein and excess generation of extracellular inorganic pyrophosphate Academic Article
Association of the ADH2*3 allele with a negative family history of alcoholism in African American young adults Academic Article
Association of the ADH2*3 allele with greater alcohol expectancies in African-American young adults Academic Article
Association of the ADHIB(*)3 allele with alcohol-related phenotypes in Trinidad Academic Article
Association study of 182 candidate genes in anorexia nervosa Academic Article
Association study of common genetic variants and HIV-1 acquisition in 6,300 infected cases and 7,200 controls Academic Article
Associations between a history of binge drinking during adolescence and self-reported responses to alcohol in young adult Native and Mexican Americans Academic Article
Associations between phylogenetic clustering and HLA profile among HIV-infected individuals in San Diego, California Academic Article
Associations of hla-dr and hla-dq types with anti-gbm nephritis by sequence-specific oligonucleotide probe hybridization Academic Article
Asthma and endotoxin: lipopolysaccharide-binding protein and soluble CD14 in bronchoalveolar compartment Academic Article
Asthma mortality rates among california youths Academic Article
Asymmetric CLASP-dependent nucleation of noncentrosomal microtubules at the trans-Golgi network Academic Article
Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9 Academic Article
Asymmetric synthesis and biological properties of uncialamycin and 26-epi-uncialamycin Academic Article
Asymmetric synthesis of inhibitors of glycinamide ribonucleotide transformylase Academic Article
Asymmetric synthesis of pochonin E and F, revision of their proposed structure, and their conversion to potent Hsp90 inhibitors Academic Article
Asymmetries in the spatial distributions of enhancing lesions and black holes in relapsing-remitting ms Academic Article
Asymptomatic liver disease in haemophiliacs Academic Article
At least 3 human type alpha-interferons - structure of alpha-2 Academic Article
At-home genetic tests Academic Article
Atenolol use and clinical outcomes after thrombolysis for acute myocardial infarction: The gusto-i experience Academic Article
Atherectomy of right coronary ostial stenoses - initial and long-term results, technical features and histologic-findings Academic Article
Atherectomy of the left main coronary-artery with percutaneous cardiopulmonary bypass support Academic Article
Atheroprotective potential of macrophage-derived phospholipid transfer protein in low-density lipoprotein receptor-deficient mice is overcome by apolipoprotein ai overexpression Academic Article
Atm deficiency affects both apoptosis and proliferation to augment myc-induced lymphomagenesis Academic Article
Atm regulates mre11-dependent DNA end-degradation and microhomology-mediated end joining Academic Article
Atmospheric oxygen inhibits growth and differentiation of marrow-derived mouse mesenchymal stem cells via a p53-dependent mechanism: Implications for long-term culture expansion Academic Article
Atmospheric pressure desorption/ionization on silicon ion trap mass spectrometry applied to the quantitation of midazolam in rat plasma and determination of midazolam 1 '-hydroxylation kinetics in human liver microsomes Academic Article
Atomic force microscopy reveals age-dependent changes in nanomechanical properties of the extracellular matrix of native human menisci: implications for joint degeneration and osteoarthritis Academic Article
Atomic structures of wild-type and thermostable mutant recombinant human cu,zn superoxide-dismutase Academic Article
Atp induces conformational changes in the carboxyl-terminal region of clc-5 Academic Article
Atp is required for receptor-mediated endocytosis in intact-cells Academic Article
Atrial fibrillation in the setting of acute myocardial infarction - irregularly irregular treatment Academic Article
Atrial fibrillation in the setting of acute myocardial infarction: The gusto-i experience Academic Article
Atrial tachypacing in the treatment of a patient with primary orthostatic hypotension Academic Article
Atrioventricular and intraventricular conduction disorders in acute myocardial infarction: A reappraisal in the thrombolytic era Academic Article
Attainment and maintenance of platelet inhibition through standard dosing of abciximab in diabetic and nondiabetic patients undergoing percutaneous coronary intervention Academic Article
Attention, probability, and task demands as determinants of p300 latency from auditory-stimuli Academic Article
Attenuated activation of macrophage tlr9 by DNA from virulent mycobacteria Academic Article
Attenuated adenosine-to-inosine editing of microRNA-376a* promotes invasiveness of glioblastoma cells Academic Article
Attenuation of HIV-1 replication in primary human cells with a designed zinc finger transcription factor Academic Article
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Blood-based gene expression signatures of infants and toddlers with autism Academic Article
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C-myc and apoptosis Academic Article
C-myc-mediated regulation of telomerase activity is disabled in immortalized cells Academic Article
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Cell acidification in apoptosis: granulocyte colony-stimulating factor delays programmed cell death in neutrophils by up-regulating the vacuolar H(+)-ATPase Academic Article
Cell activation mediated by glycosylphosphatidylinositol-anchored or transmembrane forms of CD14 Academic Article
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Cell adhesion molecules in embryogenesis and disease Academic Article
Cell based screening of inhibitors of transthyretin aggregation Academic Article
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Cell biology: The case for RNA Academic Article
Cell co-culture patterning using aqueous two-phase systems Academic Article
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Cell cycle networks link gene expression dysregulation, mutation, and brain maldevelopment in autistic toddlers Academic Article
Cell cycle regulation of human WEE1 Academic Article
Cell cycle status affects coxsackievirus replication, persistence, and reactivation in vitro Academic Article
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Cell death in cartilage Academic Article
Cell death, autoantigen cleavage, and autoimmunity Academic Article
Cell death: protein misfolding and neurodegenerative diseases Academic Article
Cell density modulates apoptosis in human articular chondrocytes Academic Article
Cell disposition of raltegravir and newer antiretrovirals in HIV-infected patients: high inter-individual variability in raltegravir cellular penetration Academic Article
Cell entry of Borna disease virus follows a clathrin-mediated endocytosis pathway that requires Rab5 and microtubules Academic Article
Cell growth and matrix invasion of ebv-immortalized human b lymphocytes is regulated by expression of alpha(v) integrins Academic Article
Cell growth inhibition and actin cytoskeleton disorganization induced by azaspiracid-1 structure-activity studies Academic Article
Cell integrins: Commonly used receptors for diverse viral pathogens Academic Article
Cell mediated immune response to the hepatitis C virus Academic Article
Cell migration and the control of post-natal T-cell lymphopoiesis in the thymus Academic Article
Cell migration without a lamellipodium: translation of actin dynamics into cell movement mediated by tropornyosin Academic Article
Cell painting with an engineered EPCR to augment the protein C system Academic Article
Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo Academic Article
Cell penetrating peptide amphiphile integrated liposomal systems for enhanced delivery of anticancer drugs to tumor cells Academic Article
Cell receptors involved in adenovirus entry Academic Article
Cell surface 4-1bbl mediates sequential signaling pathways 'downstream' of tlr and is required for sustained tnf production in macrophages Academic Article
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Cell surface remodeling by plasmin: a new function for an old enzyme Academic Article
Cell targeting with hybrid Qβ virus-like particles displaying epidermal growth factor Academic Article
Cell, isoform, and environment factors shape gradients and modulate chemotaxis Academic Article
Cell-adhesion molecules - implications for a molecular histology Academic Article
Cell-adhesion molecules in coronary-artery disease Academic Article
Cell-based optimization of novel benzamides as potential antimalarial leads Academic Article
Cell-cell adhesion by homophilic interaction of the neuronal recognition molecule axonin-1 Academic Article
Cell-free expression of disulfide-containing eukaryotic proteins for structural biology Academic Article
Cell-free human immunodeficiency virus type 1 transcytosis through primary genital epithelial cells Academic Article
Cell-penetrating peptide-mediated delivery of TALEN proteins via bioconjugation for genome engineering Academic Article
Cell-specific RNA aptamer against human CCR5 specifically targets HIV-1 susceptible cells and inhibits HIV-1 infectivity Academic Article
Cell-specific TLR9 trafficking in primary APCs of transgenic TLR9-GFP mice Academic Article
Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages Academic Article
Cell-specific down-regulation of the beta(3)-adrenergic receptor Academic Article
Cell-specific regulation of apoptosis by designed enediynes Academic Article
Cell-surface actin binds plasminogen and modulates neurotransmitter release from catecholaminergic cells Academic Article
Cell-to-cell spread of Borna disease virus proceeds in the absence of the virus primary receptor and furin-mediated processing of the virus surface glycoprotein Academic Article
Cell-type independent myc target genes reveal a primordial signature involved in biomass accumulation Academic Article
Cell-type specific penetrating peptides: therapeutic promises and challenges Academic Article
Cells expressing the RING finger Z protein are resistant to arenavirus infection Academic Article
Cellular and extracellular matrix changes in anterior cruciate ligaments during human knee aging and osteoarthritis Academic Article
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Cellular differences in lipoprotein lipase-mediated uptake of low-density lipoproteins Academic Article
Cellular immune and cytokine pathways resulting in tissue factor expression and relevance to septic shock Academic Article
Cellular immune responses to HCV core increase and HCV RNA levels decrease during successful antiretroviral therapy Academic Article
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Cellular transformation by a FERM domain mutant of the Nf2 tumor suppressor gene Academic Article
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Cellular-localization of human immunodeficiency virus-infection within the brains of acquired-immune-deficiency-syndrome patients Academic Article
Central and peripheral roles of ghrelin on glucose homeostasis Academic Article
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Central limit theorem as an approximation for intensity-based scoring function Academic Article
Central nervous system manifestations of penicillin toxicity in man Academic Article
Central venous thrombosis after cardiac operations in children Academic Article
Centralizing content and distributing labor: a community model for curating the very long tail of microbial genomes Academic Article
Centrally acting oximes in reactivation of tabun-phosphoramidated AChE Academic Article
Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication Academic Article
Centromere-specific assembly of CENP-a nucleosomes is mediated by HJURP Academic Article
Centromeres: the wild west of the post-genomic age Academic Article
Ceramide triggers budding of exosome vesicles into multivesicular endosomes Academic Article
Cerebellar lipid differences between r6/1 transgenic mice and humans with huntington's disease Academic Article
Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide Academic Article
Cerebrospinal fluid proteomics reveals potential pathogenic changes in the brains of SIV-infected monkeys Academic Article
Cerebrospinal-fluid activity of dynorphin-converting enzyme at term pregnancy Academic Article
Cerebrospinal-fluid concentrations of substance-p and (met)enkephalin-arg6-phe7 during surgery and patient-controlled analgesia Academic Article
Cerebrospinal-fluid levels of beta-endorphin in patients with fibromyalgia (fibrositis syndrome) Academic Article
Cessation of smoking followed by Prinzmetal's variant angina and diffuse esophageal spasm Academic Article
Challenges and opportunities in the investigation of unexplained intellectual disability using family-based whole-exome sequencing Academic Article
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Changepoint statistics for assessing a treatment-covariate interaction Academic Article
Changes in HIV-1 tropism: clinical and prognostic consequences Academic Article
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Changes in in vivo knee loading with a variable-stiffness intervention shoe correlate with changes in the knee adduction moment Academic Article
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Changes in striatal signaling induce remodeling of RGS complexes containing G beta 5 and R7BP subunits Academic Article
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Changes in the plasma levels of type 1 and type 2 plasminogen activator inhibitors in normal pregnancy and in patients with severe preeclampsia Academic Article
Changes in transaminases over the course of a 12-week, double-blind nalmefene trial in a 38-year-old female subject Academic Article
Changes to Medicare Part D: who benefits? Academic Article
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Chaperone displacement from mutant cystic fibrosis transmembrane conductance regulator restores its function in human airway epithelia Academic Article
Chaperones in neurodegeneration Academic Article
Characterisation of bovine lipopolysaccharide binding protein and the in vivo acute phase response to Pasteurella haemolytica Type A Academic Article
Characteristics and consequences of myocardial-infarction after percutaneous coronary intervention - insights from the coronary angioplasty versus excisional atherectomy trial (caveat) Academic Article
Characteristics and outcome of patients in whom reperfusion with intravenous tissue-type plasminogen-activator fails - results of the thrombolysis and angioplasty in myocardial-infarction (tami) i-trial Academic Article
Characteristics of Bipolar I patients grouped by externalizing disorders Academic Article
Characteristics of a soluble nuclear antigen precipitating with sera of patients with systemic lupus erythematosus Academic Article
Characteristics of antinuclear antibodies in rheumatoid arthritis. Reactivity of rheumatoid factor with a histone-dependent nuclear antigen Academic Article
Characteristics of hfe c282y homozygotes younger than age 30 years Academic Article
Characteristics of immunity induced by viral antigen or conferred by antibody via different administration routes Academic Article
Characteristics of memory B cells elicited by a highly efficacious HPV vaccine in subjects with no pre-existing immunity Academic Article
Characteristics of the modern-day physician house call Academic Article
Characteristics, treatment and outcome of patients with non-st-elevation acute coronary syndromes and multivessel coronary artery disease: Observations from pursuit (platelet glycoprotein iib/iiia in unstable angina: Receptor suppression using integrelin therapy) Academic Article
Characterization and function of the human macrophage dopaminergic system: Implications for CNS disease and drug abuse Academic Article
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Characterization and purification of truncated human rho-kinase ii expressed in sf-21 cells Academic Article
Characterization and resolution of evaporation-mediated osmolality shifts that constrain microfluidic cell culture in poly(dimethylsiloxane) devices Academic Article
Characterization and species distribution of high-affinity gtp-coupled receptors for human rantes and monocyte chemoattractant protein-1 Academic Article
Characterization by serial deletion competition elisas of hiv-1 v3 loop epitopes recognized by monoclonal antibodies Academic Article
Characterization in vitro and engraftment potential in vivo of human progenitor t cells generated from hematopoietic stem cells Academic Article
Characterization of 2 crystal forms of human defensin neutrophil cationic peptide-1, a naturally-occurring antimicrobial peptide of leukocytes Academic Article
Characterization of Alisertib (MLN8237), an investigational small-molecule inhibitor of aurora A kinase using novel in vivo pharmacodynamic assays Academic Article
Characterization of Borna disease virus p56 protein, a surface glycoprotein involved in virus entry Academic Article
Characterization of DNA in polyethylene glycol precipitated immune complexes from sera of patients with systemic lupus erythematosus Academic Article
Characterization of H7N9 influenza A viruses isolated from humans Academic Article
Characterization of HOX gene expression during myelopoiesis: role of HOX A5 in lineage commitment and maturation Academic Article
Characterization of T-5 N-oxide formation as the first highly selective measure of CYP3A5 activity Academic Article
Characterization of TAZ domains important for the induction of breast cancer stem cell properties and tumorigenesis Academic Article
Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATR. Academic Article
Characterization of a DNA-binding nuclear autoantigen mainly associated with S phase and G2 cells Academic Article
Characterization of a broadly neutralizing monoclonal antibody that targets the fusion domain of group 2 influenza A virus hemagglutinin Academic Article
Characterization of a cDNA for rhesus-monkey protein-C inhibitor - evidence for N-terminal involvement in heparin stimulation Academic Article
Characterization of a cDNA-encoding a human kidney, cytochrome-P-450 4A fatty-acid omega-hydroxylase and the cognate enzyme expressed in Escherichia-coli Academic Article
Characterization of a factor Xa binding site on factor Va near the Arg-506 activated protein C cleavage site Academic Article
Characterization of a fragment of bovine von Willebrand factor that binds to platelets Academic Article
Characterization of a human cDNA that encodes a functional receptor for platelet activating factor Academic Article
Characterization of a hypoxia-response element in the Epo locus of the pufferfish, Takifugu rubripes Academic Article
Characterization of a marsupial glutathione transferase, a class alpha enzyme from brown Antechinus (Antechinus stuartii) Academic Article
Characterization of a membrane glycoprotein having pharmacological and biochemical-properties of an at2 angiotensin-ii receptor from human myometrium Academic Article
Characterization of a membrane-surface glycoprotein associated with t-cell activation Academic Article
Characterization of a novel and potent corticotropin-releasing factor antagonist in rats Academic Article
Characterization of a nuclear deformed epidermal autoregulatory factor-1 (DEAF-1)-related (NUDR) transcriptional regulator protein Academic Article
Characterization of a patient with atypical amegakaryocytic thrombocytopenia Academic Article
Characterization of a phosphoprotein associated with the SS-B/La nuclear antigen in adenovirus-infected and uninfected KB cells Academic Article
Characterization of a putative founder mutation that accounts for the high incidence of cystinosis in brittany Academic Article
Characterization of a selective inhibitor of the parkinson's disease kinase lrrk2 Academic Article
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Characterization of a soluble IL-6 receptor α mutant C277D/H280I expressed in E-coli Academic Article
Characterization of a type-common human recombinant monoclonal antibody to herpes simplex virus with high therapeutic potential Academic Article
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Characterization of an Akt kinase inhibitor with potent pharmacodynamic and antitumor activity Academic Article
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Characterization of antibodies in human urine Academic Article
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Characterization of antigens on human lymphocytes coded by messenger RNA translated in vitro Academic Article
Characterization of autoantigenic epitopes on platelet glycoprotein IIb/IIIa using random peptide libraries Academic Article
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Characterization of circulating tumor cell aggregates identified in patients with epithelial tumors Academic Article
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Characterization of human immunodeficiency virus type 1 (HIV-1) Gag- and Gag peptide-specific CD4(+) T-cell clones from an HIV-1-seronegative donor following in vitro immunization Academic Article
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Chemoproteomic discovery of cysteine-containing human short open reading frames Academic Article
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Choices in neuroscience careers Academic Article
Cholera toxoid reactions in human volunteers: clinical and histological studies Academic Article
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Chondrocyte-derived apoptotic bodies and calcification of articular cartilage Academic Article
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Chroman-3-amides as potent Rho kinase inhibitors Academic Article
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Chromodomain antagonists that target the polycomb-group methyllysine reader protein chromobox homolog 7 (CBX7) Academic Article
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Chromosomal contact permits transcription between coregulated genes Academic Article
Chromosomal instability by inefficient Mps1 auto-activation due to a weakened mitotic checkpoint and lagging chromosomes Academic Article
Chromosomal instability estimation based on next generation sequencing and single cell genome wide copy number variation analysis Academic Article
Chromosomal integration dependent induction of junb by growth factors requires multiple flanking evolutionarily conserved sequences Academic Article
Chromosomal localization of human glutathione transferase genes of classes alpha, mu and pi Academic Article
Chromosomal location of a human alpha-interferon gene family Academic Article
Chromosomal mosaicism in neural stem cells Academic Article
Chromosome condensation caused by loss of RCC1 function requires the cdc25C protein that is located in the cytoplasm Academic Article
Chromosome transfer activates and delineates a locus control region for perforin Academic Article
Chromosome-Based Proteomic Study for Identifying Novel Protein Variants from Human Hippocampal Tissue Using Customized neXtProt and GENCODE Databases Academic Article
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Chronic acamprosate eliminates the alcohol deprivation effect while having limited effects on baseline responding for ethanol in rats Academic Article
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Chronic idiopathic thrombocytopenic purpura Academic Article
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Chronic interleukin-6 alters NMDA receptor-mediated membrane responses and enhances neurotoxicity in developing CNS neurons Academic Article
Chronic mycotic meningitis with spinal involvement (arachnoiditis) - a report of 5 cases Academic Article
Chronic treatment with novel brain-penetrating selective NOP receptor agonist MT-7716 reduces alcohol drinking and seeking in the rat Academic Article
Chronic virus-infection and immune responsiveness .2. Lactic-dehydrogenase virus-infection and immune-response to non-viral antigens Academic Article
Chronophin coordinates cell leading edge dynamics by controlling active cofilin levels Academic Article
Cigarette smoking status and outcome among patients with acute coronary syndromes without persistent st-segment elevation: Effect of inhibition of platelet glycoprotein iib/iiia with eptifibatide Academic Article
Cimetidine-induced granulocytopenia Academic Article
Ciprofloxacin-associated acute renal failure in patients undergoing high-dose chemotherapy and autologous stem cell rescue Academic Article
Circadian clock protein cryptochrome regulates the expression of proinflammatory cytokines Academic Article
Circadian control of global gene expression patterns Academic Article
Circadian physiology of metabolism Academic Article
Circadian regulation of diverse gene products revealed by mRNA expression profiling of synchronized fibroblasts Academic Article
Circadian rhythm genetics: from flies to mice to humans Academic Article
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Circadian rhythms from flies to human Academic Article
Circadian rhythms. Daily watch on metabolism Academic Article
Circular dichroism studies of glutathione reductase Academic Article
Circulating activated protein C in subjects with heterozygous GIn506-factor V Academic Article
Circulating concentrations of igf-i and icfbp-3 are not predictive of incidence or clinical behavior of pediatric osteosarcoma Academic Article
Circulating human CD4 and CD8 T cells do not have large intracellular pools of CCR5 Academic Article
Circulating immune complexes in pulmonary eosinophilic granuloma Academic Article
Circulating immune-complexes and glomerulonephritis in a patient with congenital absence of the 3rd component of complement Academic Article
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Circulating immune-complexes in idiopathic interstitial pneumonias Academic Article
Circulating immune-complexes in infective endocarditis Academic Article
Circulating immune-complexes in multiple-sclerosis and other neurological diseases Academic Article
Circulating immune-complexes in prosthetic valve endocarditis Academic Article
Circulating immune-complexes in takayasu disease Academic Article
Circulating inhibitors of blood-coagulation associated with procainamide-induced lupus-erythematosus Academic Article
Circulating microRNAs as biomarkers of radiation-induced cardiac toxicity in non-small-cell lung cancer Academic Article
Circulating tumor cells from well-differentiated lung adenocarcinoma retain cytomorphologic features of primary tumor type Academic Article
Circulating tumor microemboli diagnostics for patients with non-small-cell lung cancer Academic Article
Cis-Amide isosteric replacement in thienobenzoxepin inhibitors of PI3-kinase Academic Article
Citation Classic: The 1982 revised criteria for the classification of systemic lupus erythematosus Academic Article
Citrullination of proteins: A common post-translational modification pathway induced by different nanoparticles in vitro and in vivo Academic Article
Cks overexpression enhances chemotherapeutic efficacy by overriding DNA damage checkpoints Academic Article
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Class assignment of sequence-unrelated members of enzyme superfamilies by activity-based protein profiling Academic Article
Class ipi3k in oncogenic cellular transformation Academic Article
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Classification of PDZ domains Academic Article
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009 Academic Article
Classification of intrinsically disordered regions and proteins Academic Article
Classification of variant von Willebrand's disease subtypes by analysis of functional characteristics and multimeric composition of factor VIII/von Willebrand factor Academic Article
Classifying the evolutionary and ecological features of neoplasms Academic Article
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Clathrin-independent pinocytosis is induced in cells overexpressing a temperature-sensitive mutant of dynamin Academic Article
Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice Academic Article
Cleavage of p65/re1a of the nf-kappa b pathway by chlamydia Academic Article
Cleavage-associated neoantigenic marker for a gamma chain site in nh2-terminal aspect of fibrinogen molecule Academic Article
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Click and pick: identification of sialoside analogues for siglec-based cell targeting Academic Article
Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors Academic Article
Clickable analogue of cerulenin as chemical probe to explore protein palmitoylation Academic Article
Clinical analysis of NSCLC patients reveals lack of association between EGFR mutation and TET1 downregulation Academic Article
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Clinical development success rates for investigational drugs Academic Article
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Clinical experience with single-nucleotide polymorphism-based non-invasive prenatal screening for 22q11.2 deletion syndrome Academic Article
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Clinical neurophysiology of aging brain: From normal aging to neurodegeneration Academic Article
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Clinical outcomes of bivalirudin for ischemic heart disease Academic Article
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Clinical perspectives on neuropeptides Academic Article
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Clinical risk factors for ischemic complications after percutaneous coronary interventions: Results from the epic trial Academic Article
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Clinical trials in the gene therapy of arthritis Academic Article
Clinical trials of recombinant hirudin in acute coronary syndromes Academic Article
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Clonal analysis of the proliferation potential of human bone marrow mesenchymal stem cells as a function of potency Academic Article
Clonal characteristics of t cell infiltrates in skin and synovium of patients with psoriatic arthritis Academic Article
Clonal evolution in cancer: a tale of twisted twines Academic Article
Clonal isolation of muscle-derived cells capable of enhancing muscle regeneration and bone healing Academic Article
Clonal restriction of platelet-associated anti-gpiib/iiia autoantibodies in patients with chronic itp Academic Article
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Clonidine blocks acquisition but not expression of conditioned opiate withdrawal in rats Academic Article
Cloning and characterization of a human and murine T-cell orphan G-protein-coupled receptor similar to the growth hormone secretagogue and neurotensin receptors Academic Article
Cloning and characterization of a sub-family of human toll-like receptors: Htlr7, htlr8 and htlr9 Academic Article
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Cloning and characterization of the genes encoding the ankyrin repeat and SOCS box-containing proteins Asb-1, Asb-2, Asb-3 and Asb-4 Academic Article
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Cloning and characterization of two human G protein-coupled receptor genes (GPR38 and GPR39) related to the growth hormone secretagogue and neurotensin receptors Academic Article
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Cloning and expression of a novel human antibody-antigen pair associated with felty's syndrome Academic Article
Cloning and expression of cDNA for a human low-Km, rolipram-sensitive cyclic AMP phosphodiesterase Academic Article
Cloning and expression of ca2+-activated chloride channel from rat brain Academic Article
Cloning and expression of human gal-beta-1,3(4)glcnac alpha-2,3-sialyltransferase Academic Article
Cloning and sequence of a cDNA coding for the human beta-migrating endothelial-cell-type plasminogen activator inhibitor Academic Article
Cloning and sequencing of cDNA encoding mouse cytohesin-1 Academic Article
Cloning and sequencing of the murine homolog of the human splicing factor u2af(65) Academic Article
Cloning of a human autoimmune-response - preparation and sequencing of a human antithyroglobulin autoantibody using a combinatorial approach Academic Article
Cloning of a human cdna-encoding a cdc2-related kinase by complementation of a budding yeast cdc28 mutation Academic Article
Cloning of a novel alpha-2,3-sialyltransferase that sialylates glycoprotein and glycolipid carbohydrate groups Academic Article
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Cloning of cdnas for m-phase phosphoproteins recognized by the mpm2 monoclonal-antibody and determination of the phosphorylated epitope Academic Article
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Cloning of murine stat6 and human stat6, stat proteins that are tyrosine-phosphorylated in responses to il-4 and il-3 but are not required for mitogenesis Academic Article
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Cloning the antibody response in humans with inflammatory cns disease: Isolation of measles virus-specific antibodies from phage display libraries of a subacute sclerosing panencephalitis brain Academic Article
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Co-expression of VAL- and TMT-opsins uncovers ancient photosensory interneurons and motorneurons in the vertebrate brain Academic Article
Co-inoculation of human and murine carcinoma cells induces reciprocal suppression of metastasis by both cell lines Academic Article
Co-ligation of alpha(4)beta(1) integrin and tcr rescues human thymocytes from steroid-induced apoptosis Academic Article
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Coactivation of the human vitamin d receptor by the peroxisome proliferator-activated receptor gamma coactivator-1 alpha Academic Article
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Coexpression network analysis of neural tissue reveals perturbations in developmental processes in schizophrenia Academic Article
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Cohort profile: the Swiss HIV Cohort study Academic Article
Coiled bodies in the nucleolus of breast cancer cells Academic Article
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Colony-stimulating factor enhancement of myeloid effector cell cytotoxicity towards neuroectodermal tumor-cells Academic Article
Colorful virus-like particles: fluorescent protein packaging by the Qβ capsid Academic Article
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Combination angiostatic therapies: targeting multiple angiogenic pathways Academic Article
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Combination chemotherapy in refractory immune thrombocytopenic purpura Academic Article
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Combination of antimicrobial and endotoxin-neutralizing activities of novel oleoylamines Academic Article
Combination of fluid and solid mechanical stresses contribute to cell death and detachment in a microfluidic alveolar model Academic Article
Combination of large volume sample stacking and reversed pH junction in capillary electrophoresis for online preconcentration of glycoforms of recombinant human erythropoietin Academic Article
Combination therapy targeting both tumor-initiating and differentiated cell populations in prostate carcinoma Academic Article
Combination thrombolytic therapy - a comparison of simultaneous and sequential regimens of tissue plasminogen-activator and urokinase Academic Article
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Combinatorial antibody libraries from survivors of the turkish h5n1 avian influenza outbreak reveal virus neutralization strategies Academic Article
Combinatorial approach to N-substituted aminocyclitol libraries by solution-phase parallel synthesis and preliminary evaluation as glucocerebrosidase inhibitors Academic Article
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Combinatorial immunotherapeutic approaches to restore the function of anergic tumor-reactive cytotoxic CD8(+) T cells Academic Article
Combinatorial regulation of a signal-dependent activator by phosphorylation and acetylation Academic Article
Combinatorial use of antibodies to secreted mycobacterial proteins in a host immune system-independent test for tuberculosis Academic Article
Combinatorially inducible RNA interference triggered by chemically modified oligonucleotides Academic Article
Combined accelerated tissue-plasminogen activator and platelet glycoprotein iib/iiia integrin receptor blockade with integrin in acute myocardial infarction - results of a randomized, placebo-controlled, dose-ranging trial Academic Article
Combined functional and immunochemical analysis of normal and abnormal human factor-x Academic Article
Combined integrin phosphoproteomic analyses and small interfering RNA-based functional screening identify key regulators for cancer cell adhesion and migration Academic Article
Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial Academic Article
Combined tissue-type plasminogen-activator and prostacyclin therapy for acute myocardial-infarction Academic Article
Combined top-down and bottom-up mass spectrometric approach to characterization of biomarkers for renal disease Academic Article
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Common genetic mechanisms of blood pressure elevation in two independent rodent models of human essential hypertension Academic Article
Common genetic variants in the chromogranin a promoter alter autonomic activity and blood pressure Academic Article
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Common genetic variation near the connexin-43 gene is associated with resting heart rate in African Americans: A genome-wide association study of 13,372 participants Academic Article
Common immunological determinant between human-immunodeficiency-virus type-1 gp41 and astrocytes Academic Article
Common membrane trafficking defects of disease-associated dynamin 2 mutations Academic Article
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Common tmprss6 mutations and iron, erythrocyte, and pica phenotypes in 48 women with iron deficiency or depletion Academic Article
Common tumour p53 mutations in immortalized cells from Hupki mice heterozygous at codon 72 Academic Article
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Common variants conferring risk of schizophrenia Academic Article
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Common variants spanning PLK4 are associated with mitotic-origin aneuploidy in human embryos Academic Article
Common vs. Rare allele hypotheses for complex diseases Academic Article
Communication in neural circuits: tools, opportunities, and challenges Academic Article
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Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008 Academic Article
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Comparative analysis of human genome assemblies reveals genome-level differences Academic Article
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Comparative analysis of three murine g-protein coupled receptors activated by sphingosine-1-phosphate Academic Article
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Comparative characterization of a wild type and transmembrane domain-deleted fatty acid amide hydrolase: Identification of the transmembrane domain as a site for oligomerization Academic Article
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Comparative study of antibodies to native and denatured DNA Academic Article
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Comparison of left-ventricular function and contractile reserve after successful recanalization by thrombolysis versus rescue percutaneous trans-luminal coronary angioplasty for acute myocardial-infarction Academic Article
Comparison of lethal and nonlethal transthyretin variants and their relationship to amyloid disease Academic Article
Comparison of limulus alpha-macroglobulin with human alpha(2)-macroglobulin: Thiol ester characterization, subunit organization, and conformational change Academic Article
Comparison of long-term survival following non-Q-wave creatine kinase elevation after percutaneous coronary intervention in patients discharged on a beta blocker versus those not so treated Academic Article
Comparison of long-term usefulness-of clopidogrel therapy after the first percutaneous coronary intervention or coronary artery bypass grafting versus that after the second or repeat intervention Academic Article
Comparison of magnetic resonance imaging and transesophageal echocardiography in detection of thrombus in the left atrial appendage Academic Article
Comparison of major complication rates with new atherectomy devices for percutaneous coronary intervention in women versus men Academic Article
Comparison of mice with accelerated aging caused by distinct mechanisms Academic Article
Comparison of miniaturized time-resolved fluorescence resonance energy transfer and enzyme-coupled luciferase high-throughput screening assays to discover inhibitors of Rho-kinase II (ROCK-II) Academic Article
Comparison of neutralizing antibody assays for receptor binding and enzyme activity of the enzyme replacement therapeutic Naglazyme (galsulfase) Academic Article
Comparison of outcomes of patients with myocardial infarction when living alone versus those not living alone Academic Article
Comparison of p300 from a passive tone sequence paradigm and an active discrimination task Academic Article
Comparison of p300 from passive and active tasks for auditory and visual stimuli Academic Article
Comparison of peak serum c-reactive protein and hydroxybutyrate dehydrogenase levels in patients with acute myocardial infarction treated with alteplase and streptokinase Academic Article
Comparison of phenotype between patients with prader-willi syndrome due to deletion 15q and uniparental disomy 15 Academic Article
Comparison of procedures for testing the equality of survival distributions Academic Article
Comparison of protocols for depleting anti-E. coli antibody in immunoblotting of recombinant antigens Academic Article
Comparison of reduced alkylated derivatives of some myeloma globulins and Bence-Jones proteins Academic Article
Comparison of sibrafiban with aspirin for prevention of cardiovascular events after acute coronary syndromes: A randomised trial Academic Article
Comparison of st-segment resolution with combined fibrinolytic and glycoprotein iib/iiia inhibitor therapy versus fibrinolytic alone (data from four clinical trials) Academic Article
Comparison of stenting and balloon angioplasty for narrowings in aortocoronary saphenous vein conduits in place for more than five years Academic Article
Comparison of the abc/2 estimation technique to computer-assisted volumetric analysis of intraparenchymal and subdural hematomas complicating the gusto-1 trial Academic Article
Comparison of the activity of doxorubicin analogs using colony-forming assays and human xenografts Academic Article
Comparison of the antitumor efficacies of Her-2/neu DNA vaccines inducing contrasting IgG immunity but comparable CTL activity in mice Academic Article
Comparison of the circulating metabolite profile of PF-04991532, a hepatoselective glucokinase activator, across preclinical species and humans: potential implications in metabolites in safety testing assessment Academic Article
Comparison of the convergent receptor utilization of a retargeted feline leukemia virus envelope with a naturally-occurring porcine endogenous retrovirus a Academic Article
Comparison of the effect of etomidate and desflurane on brain tissue gases and ph during prolonged middle cerebral artery occlusion Academic Article
Comparison of the effects of apo(a) kringle IV-10 and plasminogen kringles on the interactions of lipoprotein(a) with regulatory molecules Academic Article
Comparison of the lysine binding functions of lipoprotein(a) and plasminogen Academic Article
Comparison of the safety and efficacy of emboli prevention devices versus platelet glycoprotein IIb/IIIa inhibition during carotid stenting Academic Article
Comparison of the solution conformations of human zn7 -metallothionein-2 and cd7 -metallothionein-2 using nuclear-magnetic-resonance spectroscopy Academic Article
Comparison of two platelet glycoprotein IIb/IIIa inhibitors, tirofiban and abciximab, for the prevention of ischemic events with percutaneous coronary revascularization Academic Article
Comparisons of Bence-Jones proteins and L polypeptide chains of myeloma globulins after hydrolysis with trypsin Academic Article
Comparisons of characteristics and outcomes among women and men with acute myocardial infarction treated with thrombolytic therapy Academic Article
Comparisons of several biological and physicochemical properties of human-leukocyte interferons produced by human-leukocytes and by escherichia-coli Academic Article
Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis Academic Article
Competition between Xenopus satellite-I sequences and Pol-III genes for stable transcription complex-formation Academic Article
Competition between bactericidal permeability-increasing protein and lipopolysaccharide-binding protein for lipopolysaccharide binding to monocytes Academic Article
Competition between plasminogen and tissue plasminogen activator for cellular binding sites Academic Article
Competition of activated protein-C and urokinase for a heparin-dependent inhibitor Academic Article
Complement activation by a univalent hapten-antibody complex Academic Article
Complement activation in vitro by antiplatelet antibodies in chronic immune thrombocytopenic purpura Academic Article
Complement and immunoglobulin deposits in the skin of patients with atopic dermatitis Academic Article
Complement and infectious agents - a tale of disguise and deception Academic Article
Complement is activated by IgG hexamers assembled at the cell surface Academic Article
Complement, viruses, and virus-infected cells Academic Article
Complement-activating abilities of defined antinuclear antibodies Academic Article
Complement-mediated binding of monocytes to intermediate filaments in vitro Academic Article
Complementary clinical benefits of coronary-artery stenting and blockade of platelet glycoprotein IIb/IIIa receptors. Evaluation of Platelet IIb/IIIa Inhibition in Stenting Investigators Academic Article
Complementation of a fibre mutant adenovirus by packaging cell lines stably expressing the adenovirus type 5 fibre protein Academic Article
Complementation of defective leucine decarboxylation in fibroblasts from a maple syrup urine disease patient by retrovirus-mediated gene transfer Academic Article
Complete abolishment of coagulant activity in monomeric disulfide-deficient tissue factor Academic Article
Complete amino-acid sequence of a human monocyte chemoattractant, a putative mediator of cellular immune-reactions Academic Article
Complete atrioventricular-block complicating inferior wall acute myocardial-infarction treated with reperfusion therapy Academic Article
Complete enzymatic deglycosylation of native sex steroid-binding protein (SBP or SHBG) of human and rabbit plasma: effect on the steroid-binding activity Academic Article
Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer Academic Article
Complete primary structure of porcine tenascin - detection of tenascin transcripts in adult submaxillary-glands Academic Article
Complete protein characterization using top-down mass spectrometry and ultraviolet photodissociation Academic Article
Complete replication of hepatitis C virus in cell culture Academic Article
Complete sequence of the human-tissue factor gene, a highly regulated cellular receptor that initiates the coagulation protease cascade Academic Article
Completion of the entire hepatitis C virus life cycle in genetically humanized mice Academic Article
Complex formation between urokinase and plasma protein C inhibitor in vitro and in vivo Academic Article
Complex genetic organization of junB: multiple blocks of flanking evolutionarily conserved sequence at the murine and human junB loci Academic Article
Complex genomic rearrangement in the SOX9 5' region in a patient with Pierre Robin sequence and hypoplastic left scapula Academic Article
Complex of a protective antibody with its ebola virus gp peptide epitope: Unusual features of a v lambda(x) light chain Academic Article
Complex patterns of genomic admixture within southern Africa Academic Article
Complexes of activated protein-C with alpha-1-antitrypsin in normal-pregnancy and in severe preeclampsia Academic Article
Complications associated with central venous catheters used for the collection of peripheral blood progenitor cells to support high-dose chemotherapy and autologous stem cell rescue Academic Article
Comprehensive analysis and identification of the human STIM1 domains for structural and functional studies Academic Article
Comprehensive analysis of structure-activity relationships of a-ketoheterocycles as sn-1-diacylglycerol lipase a inhibitors Academic Article
Comprehensive cross-clade neutralization analysis of a panel of anti-human immunodeficiency virus type 1 monoclonal antibodies Academic Article
Comprehensive gene- and pathway-based analysis of depressive symptoms in older adults Academic Article
Comprehensive linkage and linkage heterogeneity analysis of 4344 sibling pairs affected with hypertension from the family blood pressure program Academic Article
Comprehensive mapping of histone modifications at DNA double-strand breaks deciphers repair pathway chromatin signatures Academic Article
Comprehensive microrna profiling reveals a unique human embryonic stem cell signature dominated by a single seed sequence Academic Article
Comprehensive molecular characterization of human adipocytes reveals a transient brown phenotype Academic Article
Comprehensive peptidomimetic libraries targeting protein-protein interactions Academic Article
Comprehensive study of sansalvamide a derivatives and their structure-activity relationships against drug-resistant colon cancer cell lines Academic Article
Compromised mutant EFEMP1 secretion associated with macular dystrophy remedied by proteostasis network alteration Academic Article
Compulsive drug-seeking behavior and relapse. Neuroadaptation, stress, and conditioning factors Academic Article
Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells Academic Article
Computational design of high-affinity epitope scaffolds by backbone grafting of a linear epitope Academic Article
Computational evaluation of protein-small molecule binding Academic Article
Computational investigation of RNA CUG repeats responsible for myotonic dystrophy 1 Academic Article
Computational prediction of atomic structures of helical membrane proteins aided by em maps Academic Article
Computational prediction of broadly neutralizing HIV-1 antibody epitopes from neutralization activity data Academic Article
Computational screening and design for compounds that disrupt protein-protein interactions Academic Article
Computational tools for epitope vaccine design and evaluation Academic Article
Computational wear simulation of patellofemoral articular cartilage during in vitro testing Academic Article
Computational, pulse-radiolytic, and structural investigations of lysine-136 and its role in the electrostatic triad of human Cu,Zn superoxide dismutase Academic Article
Computer vision's potential to improve health care Academic Article
Computer-assisted versus manual alignment in THA: a probabilistic approach to range of motion Academic Article
Computer-controlled microcirculatory support system for endothelial cell culture and shearing Academic Article
Comt polymorphisms and anxiety-related personality traits Academic Article
Concentrates of clotting-factor IX Academic Article
Concept, design and implementation of a cardiovascular gene-centric 50 k snp array for large-scale genomic association studies Academic Article
Concise review: A chemical approach to control cell fate and function Academic Article
Concise review: Mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair. Current views Academic Article
Concise review: chemical approaches for modulating lineage-specific stem cells and progenitors Academic Article
Condensin I and II complexes license full estrogen receptor α-dependent enhancer activation Academic Article
Conditional regulation of the human CYP4X1 and CYP4Z1 genes Academic Article
Conditioned opioid withdrawal decreases nociceptin/orphanin cortex and olfactory fq levels in the frontal cortex and olfactory tubercle Academic Article
Conditions influencing human sperm capacitation and penetration of zona-free hamster ova Academic Article
Conformation of prpc on the cell surface as probed by antibodies Academic Article
Conformation of the carboxy-terminal region of the a-alpha chain of fibrinogen as elucidated by immunochemical analyses Academic Article
Conformational adaptation of human cytochrome p450 2b6 and rabbit cytochrome p450 2b4 revealed upon binding multiple amlodipine molecules Academic Article
Conformational and structural modulation of nh2-terminal regions of fibrinogen and fibrin associated with plasmin cleavage Academic Article
Conformational changes in fibrinogen elicited by its interaction with platelet membrane glycoprotein GPIIb-IIIa Academic Article
Conformational changes in nitric oxide synthases induced by chlorzoxazone and nitroindazoles: crystallographic and computational analyses of inhibitor potency Academic Article
Conformational changes in the A1 domain of von Willebrand factor modulating the interaction with platelet glycoprotein Ibα Academic Article
Conformational changes induced in the envelope glycoproteins of the human and simian immunodeficiency viruses by soluble receptor binding Academic Article
Conformational changes of gp120 in epitopes near the ccr5 binding site are induced by cd4 and a cd4 miniprotein mimetic Academic Article
Conformational constraints imposed on a pan-neutralizing hiv-1 antibody epitope result in increased antigenicity but not neutralizing response Academic Article
Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding Academic Article
Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions Academic Article
Conformational flexibility in crystal structures of human 11 β-hydroxysteroid dehydrogenase type I provide insights into glucocorticoid interconversion and enzyme regulation Academic Article
Conformational flexibility underlies ubiquitin ligation mediated by the WWP1HECT domain E3 ligase Academic Article
Conformational heterogeneity and the affinity of substrate molecular recognition by cytochrome P450cam Academic Article
Conformational isomerism can limit antibody catalysis Academic Article
Conformational polymorphism of cyclosporine-a Academic Article
Conformational states of the full-length glucagon receptor Academic Article
Conformational studies of synthetic fragment 1-34 of human parathyroid-hormone by NMR techniques Academic Article
Conformationally homogeneous heterocyclic pseudotetrapeptides as three-dimensional scaffolds for rational drug design: Receptor-selective somatostatin analogues Academic Article
Conformationally restricted analogues designed for selective inhibition of GAR Tfase versus thymidylate synthase or dihydrofolate reductase Academic Article
Confronting the issues of patient safety and investigator conflict-of-interest in an international clinical-trial of myocardial reperfusion Academic Article
Congenital disease snps target lineage specific structural elements in protein kinases Academic Article
Congenital myopathy-causing tropomyosin mutations induce thin filament dysfunction via distinct physiological mechanisms Academic Article
Conjugation of functionalized gadolinium metallofullerenes with IL-13 peptides for targeting and imaging glial tumors Academic Article
Conjugation of highly reactive aflatoxin B1 exo-8,9-epoxide catalyzed by rat and human glutathione transferases: estimation of kinetic parameters Academic Article
Conjugation of styrene oxide by the basic and acidic forms of glutathione transferase in the human fetal liver Academic Article
Conjunctive use of platelet glycoprotein IIb/IIIa antagonists and thrombolytic therapy for acute myocardial infarction Academic Article
Connectivity and complexity: The relationship between neuroanatomy and brain dynamics Academic Article
Connexin mediated cataract prevention in mice Academic Article
Connexins in lens development and cataractogenesis Academic Article
Consensus generation and variant detection by celera assembler Academic Article
Consequences of reocclusion after successful reperfusion therapy in acute myocardial-infarction Academic Article
Consequences of secondary or coinfections for immunity Academic Article
Consequences of the loss of o-linked glycosylation of meningococcal type iv pilin on piliation and pilus-mediated adhesion Academic Article
Conservation of function and regulation within the cdc28/cdc2 protein-kinase family - characterization of the human cdc2hs protein-kinase in saccharomyces-cerevisiae Academic Article
Conservation of function between mammalian and plant steroid 5α-reductases Academic Article
Conservation of the low-density-lipoprotein receptor-binding domain of apoprotein-b - demonstration by a new monoclonal-antibody, mb47 Academic Article
Conservation of tissue factor primary sequence among 3 mammalian-species Academic Article
Conserved and heterogeneous lipid antigen specificities of CD1d-restricted NKT cell receptors Academic Article
Conserved binding mode of human beta(2) adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography Academic Article
Conserved changes in envelope function during human immunodeficiency virus type 1 coreceptor switching Academic Article
Conserved chromosomal location and genomic structure of human and mouse fatty-acid amide hydrolase genes and evaluation of clasper as a candidate neurological mutation Academic Article
Conserved features of intermediates in amyloid assembly determine their benign or toxic states Academic Article
Conserved functions of membrane active gtpases in coated vesicle formation Academic Article
Conserved linkage between the puffer fish (Fugu rubripes) and human genes for platelet-derived growth factor receptor and macrophage colony-stimulating factor receptor Academic Article
Conserved primary sequences of the DNA terminal proteins of 5 different human adenovirus groups Academic Article
Conserved receptor-binding domains of Lake Victoria marburgvirus and Zaire ebolavirus bind a common receptor Academic Article
Conserved regulation of the lymphocyte-specific expression of lck in the Fugu and mammals Academic Article
Conserved residues in lassa fever virus Z protein modulate viral infectivity at the level of the ribonucleoprotein Academic Article
Conserved sequence-specific lincRNA-steroid receptor interactions drive transcriptional repression and direct cell fate Academic Article
Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes Academic Article
Conserved structural motifs governing the stoichiometric repair of alkylated DNA by o-6-alkylguanine-DNA alkyltransferase Academic Article
Conserved synteny between the Fugu and human PTEN locus and the evolutionary conservation of vertebrate PTEN function Academic Article
Conserved synteny between the chicken Z sex chromosome and human chromosome 9 includes the male regulatory gene DMRT1: a comparative (re)view on avian sex determination Academic Article
Considerable interindividual variation in the pharmacokinetics of tolperisone hcl Academic Article
Considerations in the medical management of pregnancy in transplant recipients Academic Article
Considerations on temperature, longevity and aging Academic Article
Consistency of T2 gene signatures in severe asthma key to effective treatments or merely the tip of the iceberg? Academic Article
Constitutional aneuploidy in the normal human brain Academic Article
Constitutional delay in growth and puberty (CDGP) is associated with hypoleptinaemia Academic Article
Constitutive activation of integrin alpha 4 beta 1 defines a unique stage of human thymocyte development Academic Article
Constitutive activity of the melanocortin-4 receptor is maintained by its n-terminal domain and plays a role in energy homeostasis in humans Academic Article
Constitutive activity of the tumor necrosis factor promoter is canceled by the 3' untranslated region in nonmacrophage cell lines; a trans-dominant factor overcomes this suppressive effect Academic Article
Constitutive c-myc expression in an il-3-dependent myeloid cell-line suppresses cell-cycle arrest and accelerates apoptosis Academic Article
Constitutive expression of murine decay-accelerating factor 1 is controlled by the transcription factor sp1 Academic Article
Constitutive intra-articular expression of human IL-1 beta following gene transfer to rabbit synovium produces all major pathologies of human rheumatoid arthritis Academic Article
Constitutive nadph oxidase 4 activity resides in the composition of the b-loop and the penultimate c terminus Academic Article
Constitutive, long-term production of human interferons by hamster-cells containing multiple copies of a cloned interferon gene Academic Article
Constitutively active rheb induces oncogenic transformation Academic Article
Constructing de novo H2O2 signaling via induced protein proximity Academic Article
Constructing molecular complexity and diversity: Total synthesis of natural products of biological and medicinal importance Academic Article
Construction and characterization of retroviral vectors expressing biologically active human interleukin-12 Academic Article
Construction of retroviral vectors with improved safety, gene expression, and versatility Academic Article
Construction, affinity maturation, and biological characterization of an anti-tumor-associated glycoprotein-72 humanized antibody Academic Article
Consumer perceptions of direct-to-consumer personalized genomic risk assessments Academic Article
Contact inhibition against senescence Academic Article
Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals Academic Article
Contemporary North American influenza H7 viruses possess human receptor specificity: Implications for virus transmissibility Academic Article
Contemporary clinical-trials of restenosis Academic Article
Contemporary human genetic strategies in aging research Academic Article
Contemporary reperfusion therapy for cardiogenic-shock - the gusto-i trial experience Academic Article
Contemporary, yeast-based approaches to understanding human genetic variation Academic Article
Contenders in fasl/tnf death signaling Academic Article
Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies Academic Article
Context-dependent effects of asparagine glycosylation on Pin WW folding kinetics and thermodynamics Academic Article
Context-dependent proangiogenic function of bone morphogenetic protein signaling is mediated by disabled homolog 2 Academic Article
Continuing education course #2: Current understanding of hemostasis Academic Article
Continuous 12-lead st-segment recovery analysis in the tami 7 study - performance of a noninvasive method for real-time detection of failed myocardial reperfusion Academic Article
Continuous in vitro evolution of a ribozyme ligase: a model experiment for the evolution of a biomolecule Academic Article
Continuous production of carcinoembryonic antigen in hollow fiber cell-culture units - brief communication Academic Article
Contrasting IgG structures reveal extreme asymmetry and flexibility Academic Article
Contribution of 20 single nucleotide polymorphisms of 13 genes to dyslipidemia associated with antiretroviral therapy Academic Article
Contribution of LCMV towards deciphering biology of quasispecies in vivo Academic Article
Contribution of amino acid residue 208 in the hydrophobic binding site to the catalytic mechanism of human glutathione transferase A1-1 Academic Article
Contribution of charged amino acids in the CDR2 region of CD4 to HIV-1 gp120 binding Academic Article
Contribution of distinct adhesive interactions to platelet aggregation in flowing blood Academic Article
Contribution of five amino acid residues in the glutathione-binding site to the function of human glutathione transferase P1-1 Academic Article
Contribution of genetic background, traditional risk factors, and HIV-related factors to coronary artery disease events in HIV-positive persons Academic Article
Contribution of genome-wide significant single-nucleotide polymorphisms and antiretroviral therapy to dyslipidemia in HIV-infected individuals: a longitudinal study Academic Article
Contribution of glutamatergic signaling to nitrosative stress-induced protein misfolding in normal brain aging and neurodegenerative diseases Academic Article
Contribution of glutathione transferase M3-3 to 1,3-bis(2-chloroethyl)-1-nitrosourea resistance in a human non-small cell lung cancer cell line Academic Article
Contribution of glycine 146 to a conserved folding module affecting stability and refolding of human glutathione transferase P1-1 Academic Article
Contribution of histidine-rich glycoprotein in clearance of immune complexes and apoptotic cells: Implications for ameliorating autoimmune diseases Academic Article
Contribution of human manganese superoxide dismutase tyrosine 34 to structure and catalysis Academic Article
Contribution of leptin receptor N-linked glycans to leptin binding Academic Article
Contribution of mutations in known Mendelian glaucoma genes to advanced early-onset primary open-angle glaucoma Academic Article
Contribution of platelets to tumour metastasis Academic Article
Contribution of proteoglycans to human immunodeficiency virus type 1 brain invasion Academic Article
Contribution of receptor editing to the antibody repertoire Academic Article
Contributions of ethnicity to differential item functioning of cannabis abuse and dependence symptoms Academic Article
Contributions of human-platelets to the proteolytic activation of blood-coagulation factor-XII and factor-XI Academic Article
Contributions of individual nucleotides to tertiary binding of substrate by a Pneumocystis carinii group I intron Academic Article
Contributions of ionic interactions and protein dynamics to cytochrome P450 2D6 (CYP2D6) substrate and inhibitor binding Academic Article
Control of craving by the prefrontal cortex Academic Article
Control of developmental regulator's by Polycomb in human embryonic stem cells Academic Article
Control of egf receptor signaling by clathrin-mediated endocytosis Academic Article
Control of interneuron dendritic growth through NRG1/erbB4-mediated kalirin-7 disinhibition Academic Article
Control of lipopolysaccharide (lps) binding and lps-induced tumor-necrosis-factor secretion in human peripheral-blood monocytes Academic Article
Control of lipopolysaccharide high-density lipoprotein interactions by an acute-phase reactant in human-serum Academic Article
Control of rna processing by a large non-coding rna over-expressed in carcinomas Academic Article
Control of the g(1)/s transition Academic Article
Control of translocations between highly diverged genes by Sgs1, the Saccharomyces cerevisiae homolog of the Bloom's syndrome protein Academic Article
Controlled transcription of a human alpha-interferon gene introduced into mouse l-cells Academic Article
Controlling activation of the RNA-dependent protein kinase by siRNAs using site-specific chemical modification Academic Article
Controlling mammalian gene expression by allosteric hepatitis delta virus ribozymes Academic Article
Controlling mutation: Intervening in evolution as a therapeutic strategy Academic Article
Controlling transcription with noncoding RNAs in mammalian cells Academic Article
Convergence of atherosclerosis and alzheimer's disease: Inflammation, cholesterol, and misfolded proteins Academic Article
Convergence of independent DISC1 mutations on impaired neurite growth via decreased UNC5D expression Academic Article
Convergent functional genomic studies of omega-3 fatty acids in stress reactivity, bipolar disorder and alcoholism Academic Article
Convergent functional genomics of anxiety disorders: Translational identification of genes, biomarkers, pathways and mechanisms Academic Article
Convergent functional genomics of bipolar disorder: From animal model pharmacogenomics to human genetics and biomarkers Academic Article
Convergent functional genomics of genome-wide association data for bipolar disorder: Comprehensive identification of candidate genes, pathways and mechanisms Academic Article
Convergent functional genomics of psychiatric disorders Academic Article
Convergent functional genomics of schizophrenia: From comprehensive understanding to genetic risk prediction Academic Article
Convergent functional genomics of stem cell-derived cells Academic Article
Convergent functional genomics: a Bayesian candidate gene identification approach for complex disorders Academic Article
Convergent functional genomics: application to bipolar disorder Academic Article
Convergent functional genomics: what we have learned and can learn about genes, pathways, and mechanisms Academic Article
Convergent integration of animal model and human studies of bipolar disorder (manic-depressive illness) Academic Article
Conversion of Glu-plasminogen to Lys-plasminogen is necessary for optimal stimulation of plasminogen activation on the endothelial cell surface Academic Article
Conversion of human fibroblasts into functional cardiomyocytes by small molecules Academic Article
Conversion of human fibroblasts to angioblast-like progenitor cells Academic Article
Conversion of human fibroblasts to functional endothelial cells by defined factors Academic Article
Converting IL-15 to a superagonist by binding to soluble IL-15R alpha Academic Article
Converting an injectable protein therapeutic into an oral form: Phenylalanine ammonia lyase for phenylketonuria Academic Article
Converting mouse epiblast stem cells into mouse embryonic stem cells by using small molecules Academic Article
Converting stem cells to dendritic cells by agonist antibodies from unbiased morphogenic selections Academic Article
Convulxin binds to native, human glycoprotein IIbα Academic Article
Cooperation of human tumor-reactive CD4+ and CD8+ T cells after redirection of their specificity by a high-affinity p53A2.1-specific TCR Academic Article
Cooperation of tissue factor cytoplasmic domain and par2 signaling in breast cancer development Academic Article
Cooperative binding of acetaminophen and caffeine within the P450 3A4 active site Academic Article
Cooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expression Academic Article
Cooperativity enables non-neutralizing antibodies to neutralize Ebolavirus Academic Article
Cooperativity in RNA-protein interactions: Global analysis of RNA binding specificity Academic Article
Cooperativity in transcription factor binding to the coactivator creb-binding protein (cbp) - the mixed lineage leukemia protein (mll) activation domain binds to an allosteric site on the kix domain Academic Article
Coordinate activation of endogenous p38 alpha, beta, gamma, and delta by inflammatory stimuli Academic Article
Coordinated regulation of accessory genetic elements produces cyclic di-nucleotides for V. cholerae virulence Academic Article
Copper-based pulsed dipolar ESR spectroscopy as a probe of protein conformation linked to disease states Academic Article
Copy Number Variation of KIR Genes Influences HIV-1 Control Academic Article
Copy number variations associated with obesity-related traits in African Americans: a joint analysis between GENOA and HyperGEN Academic Article
Copy number variations of TBK1 in Australian patients with primary open-angle glaucoma Academic Article
Cord blood-plasma lipoproteins inhibit mitogen-stimulated lymphocyte-proliferation Academic Article
Core transcriptional regulatory circuitry in human embryonic stem cells Academic Article
Coreceptor affinity for MHC defines peptide specificity requirements for TCR interaction with coagonist peptide-MHC Academic Article
Coregulator interactions with the thyroid hormone receptor Academic Article
Coronary angiography after thrombolytic therapy for acute myocardial-infarction Academic Article
Coronary angioplasty as primary therapy for acute myocardial-infarction 6 to 48 hours after symptom onset - report of an initial experience Academic Article
Coronary angioplasty as therapy for acute myocardial infarction: University of Michigan experience Academic Article
Coronary angioplasty for acute myocardial-infarction Academic Article
Coronary angioplasty in myocardial infarction Academic Article
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Coronary angioplasty volume-outcome relationships for hospitals and cardiologists Academic Article
Coronary arterial thrombolysis with combined infusion of recombinant tissue-type plasminogen-activator and urokinase in patients with acute myocardial-infarction Academic Article
Coronary artery stents Academic Article
Coronary insufficiency in children - coronary arteriographic studies in 2 siblings from a family with hyperbetalipoproteinemia Academic Article
Coronary morphological and clinical determinants of procedural outcome with angioplasty for multivessel coronary-disease - implications for patient selection Academic Article
Coronary revascularization after intravenous tissue plasminogen-activator for unstable angina-pectoris - results of a randomized, double-blind, placebo-controlled trial Academic Article
Coronary revascularization surgery after myocardial infarction: Impact of bypass surgery on survival after thrombolysis Academic Article
Coronary thrombolysis with recombinant human tissue-type plasminogen-activator - a prospective, randomized, placebo-controlled trial Academic Article
Coronary thrombolysis with recombinant tissue-type plasminogen-activator - a hematologic and pharmacologic study Academic Article
Coronary-artery spasm and cardiac-arrest in carcinoid heart-disease Academic Article
Coronary-bypass surgery improves global and regional left-ventricular function following thrombolytic therapy for acute myocardial-infarction Academic Article
Coronaviruses and arteriviruses display striking differences in their cyclophilin A-dependence during replication in cell culture Academic Article
Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations Academic Article
Correlates between autoantibodies to nucleolar antigens and clinical-features in patients with systemic-sclerosis (scleroderma) Academic Article
Correlates of in-hospital cost among patients undergoing abdominal aortic aneurysm repair Academic Article
Correlating structure and function of drug-metabolizing enzymes: progress and ongoing challenges Academic Article
Correlation analysis of genetic admixture and social identification with body mass index in a Native American community Academic Article
Correlation between MMP-13 and HDAC7 expression in human knee osteoarthritis Academic Article
Correlation between NS5A dimerization and hepatitis C virus replication Academic Article
Correlation between anatomic features and low-field magnetic resonance imaging of the equine metacarpophalangeal joint Academic Article
Correlation between base-line plasminogen-activator inhibitor levels and clinical outcome during therapy with tissue plasminogen-activator for acute myocardial-infarction Academic Article
Correlation between circulating levels of von Willebrand's antigen II and von Willebrand factor: discrimination between type I and type II von Willebrand's disease Academic Article
Correlation between the knee adduction torque and medial contact force for a variety of gait patterns Academic Article
Correlation of a common mutation in the methylenetetrahydrofolate reductase gene with plasma homocysteine in patients with premature coronary artery disease Academic Article
Correlation of chondroitin sulfate proteoglycan expression on proliferating brain capillary endothelial-cells with the malignant phenotype of astroglial cells Academic Article
Correlation of farnesoid x receptor coactivator recruitment and cholesterol 7 alpha-hydroxylase gene repression by bile acids Academic Article
Correlation of interleukin-1-beta and cachectin concentrations in cerebrospinal-fluid and outcome from bacterial-meningitis Academic Article
Correlation of naturally occurring HIV-1 resistance to DEB025 with capsid amino acid polymorphisms Academic Article
Correlation of serum c3dp levels with chemotherapeutic management of cancer-patients Academic Article
Corroboration of recent models of γG immunoglobulin molecule Academic Article
Corticotropin releasing factor: a key role in the neurobiology of addiction Academic Article
Corticotropin releasing-factor (crf) - immunoreactive neurons and fibers in rat hypothalamus Academic Article
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Corticotropin-releasing factor, norepinephrine, and stress Academic Article
Cortisol responses following placebo and alcohol in Asians with different ALDH2 genotypes Academic Article
Cortistatin a is a high-affinity ligand of protein kinases rock, cdk8, and cdk11 Academic Article
Cost effectiveness of early discharge after uncomplicated acute myocardial infarction Academic Article
Cost of cardiac care in the three years after coronary catheterization in a contained care system: Critical determinants and implications Academic Article
Cost of failure to project impact of protein science on human health and economy Academic Article
Cost-effectiveness of clopidogrel plus aspirin versus aspirin alone for secondary prevention of cardiovascular events: Results from the charisma trial Academic Article
Cost-effectiveness of platelet glycoprotein IIb/IIIa inhibition with eptifibatide in patients with non-ST-elevation acute coronary syndromes Academic Article
Cost-effectiveness of thrombolytic therapy with tissue-plasminogen activator as compared with streptokinase for acute myocardial-infarction Academic Article
Cost-efficacy modeling of catheter reuse for percutaneous transluminal coronary angioplasty Academic Article
Costly mistakes: translational infidelity and protein homeostasis Academic Article
Coumarin derivatives as substrate probes of mammalian cytochromes P450 2B4 and 2B6: assessing the importance of 7-Alkoxy chain length, halogen substitution, and non-active site mutations Academic Article
Coumarin necrosis, neonatal purpura fulminans, and protein C deficiency Academic Article
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Counteraction of HLA-C-mediated immune control of HIV-1 by Nef Academic Article
Coupled redox potentials in manganese and iron superoxide dismutases from reaction kinetics and density functional/electrostatics calculations Academic Article
Coupling of folding and binding for unstructured proteins Academic Article
Coupling of receptor conformation and ligand orientation determine graded activity Academic Article
Coupling of the adhesive receptor cd11b/cd18 to functional enhancement of effector macrophage tissue factor response Academic Article
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Covalent inhibitors: an opportunity for rational target selectivity Academic Article
Covalent ligand discovery against druggable hotspots targeted by anti-cancer natural products Academic Article
Covalent small-molecule-RNA complex formation enables cellular profiling of small-molecule-RNA interactions Academic Article
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Coxsackievirus B3 proteins directionally complement each other to downregulate surface major histocompatibility complex class I Academic Article
Coxsackievirus b3 inhibits antigen presentation in vivo, exerting a profound and selective effect on the mhc class i pathway Academic Article
Coxsackievirus can exploit LC3 in both autophagy-dependent and -independent manners in vivo Academic Article
Coxsackievirus infection induces autophagy-like vesicles and megaphagosomes in pancreatic acinar cells in vivo Academic Article
Coxsackievirus infection of the pancreas: Evaluation of receptor expression, pathogenesis, and immunopathology Academic Article
Coxsackievirus replication and the cell cycle: A potential regulatory mechanism for viral persistence/latency Academic Article
CpG methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene Academic Article
Cr-2 is a complement activator and the covalent binding-site for c-3 during alternative pathway activation by raji cells Academic Article
Craving in response to stress induction in a human laboratory paradigm predicts treatment outcome in alcohol-dependent individuals Academic Article
Craving, context and the cortex Academic Article
Creatine kinase-mb elevation after coronary artery bypass grafting surgery in patients with non-st-segment elevation acute coronary syndromes predict worse outcomes: Results from four large clinical trials Academic Article
Creatine kinase-mb elevation after percutaneous coronary intervention predicts adverse outcomes in patients with acute coronary syndromes Academic Article
Creatine-kinase mm and mb isoforms in patients receiving thrombolytic therapy and acute angiography Academic Article
Creation of a large-scale genetic data bank for cardiovascular association studies Academic Article
Creep of trabecular bone from the human proximal tibia Academic Article
Creutzfeldt-Jakob disease Academic Article
Criteria for environmentally associated autoimmune diseases Academic Article
Critical evaluation of bispecific antibodies as targetins agents for boron neutron capture therapy of brain tumors Academic Article
Critical role for conversion of Glu-plasminogen to Lys-plasminogen for optimal stimulation of plasminogen activation on cell surfaces Academic Article
Cross-clade neutralization of primary isolates of human immunodeficiency virus type 1 by human monoclonal antibodies and tetrameric CD4-IgG Academic Article
Cross-linking of lipopolysaccharide (lps) to cd14 on thp-1 cells mediated by lps-binding protein Academic Article
Cross-neutralization of human and palm civet severe acute respiratory syndrome coronaviruses by antibodies targeting the receptor-binding domain of spike protein Academic Article
Cross-neutralizing activity of human anti-V3 monoclonal antibodies derived from non-B clade HIV-1 infected individuals Academic Article
Cross-reactive and potent neutralizing antibody responses in human survivors of natural Ebolavirus infection Academic Article
Cross-reactive epitope with klebsiella-pneumoniae nitrogenase in articular tissue of hla-b27+ patients with ankylosing-spondylitis Academic Article
Cross-reactivity between hl-a and h-2 antigens. Ii. Allogeneic sensitization by xenogeneic soluble lymphocyte antigens (hl-a) Academic Article
Cross-talk between IRAK-4 and the NADPH oxidase Academic Article
Cross-talk between intraepithelial gamma delta T cells and epithelial cells Academic Article
Cross-talk between receptor tyrosine kinase and tumor necrosis factor-α signaling networks regulates apoptosis but not proliferation Academic Article
Cross-talk between snurportin1 subdomains Academic Article
Cross-talk of integrin alpha 3 beta 1 and tissue factor in cell migration Academic Article
Crowdsourcing in biomedicine: challenges and opportunities Academic Article
Cryo-EM structure of a native, fully glycosylated, cleaved HIV-1 envelope trimer Academic Article
Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating Academic Article
Cryo-EM structures and atomic model of the HIV-1 strand transfer complex intasome Academic Article
Cryo-EM visualization of a viral internal ribosome entry site bound to human ribosomes: The IRES functions as an RNA-Based translation factor Academic Article
Cryo-electron microscopy structure of adenovirus type 2 temperature-sensitive mutant 1 reveals insight into the cell entry defect Academic Article
Cryo-em visualization of an exposed rgd epitope on adenovirus that escapes antibody neutralization Academic Article
Cryopreservation by slow cooling with dmso diminished production of oct-4 pluripotency marker in human embryonic stem cells Academic Article
Cryopreservation of cancer-initiating cells derived from glioblastoma Academic Article
Cryopreservation of human mucosal tissues Academic Article
Cryopreservation of neurospheres derived from human glioblastoma multiforme Academic Article
Cryptochromes mediate rhythmic repression of the glucocorticoid receptor Academic Article
Cryptochromes: bringing the blues to circadian rhythms Academic Article
Crystal structure and activity studies of the C11 cysteine peptidase from parabacteroides merdae in the human gut microbiome Academic Article
Crystal structure and mutational analysis of the saccharomyces cerevisiae cell cycle regulatory protein cks1: Implications for domain swapping, anion binding and protein interactions Academic Article
Crystal structure and mutational analysis the human cdk2 kinase complex with cell cycle-regulatory protein ckshs1 Academic Article
Crystal structure and site-specific mutagenesis of pterin-bound human phenylalanine hydroxylase Academic Article
Crystal structure of 3-hydroxyanthranilic acid 3,4-dioxygenase from saccharomyces cerevisiae: A special subgroup of the type III extradiol dioxygenases Academic Article
Crystal structure of CD1a in complex with a sulfatide self antigen at a resolution of 2.15 A Academic Article
Crystal structure of MHC class II I-Ab in complex with a human CLIP peptide: prediction of an I-Ab peptide-binding motif Academic Article
Crystal structure of PG16 and chimeric dissection with somatically related PG9: structure-function analysis of two quaternary-specific antibodies that effectively neutralize HIV-1 Academic Article
Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II, in complex with a transition state analogue Academic Article
Crystal structure of TM1367 from Thermotoga maritima at 1.90 Å resolution reveals an atypical member of the cyclophilin (peptidylprolyl isomerase) fold Academic Article
Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors Academic Article
Crystal structure of a cocaine-binding antibody Academic Article
Crystal structure of a cytochrome P450 2B6 genetic variant in complex with the inhibitor 4-(4-chlorophenyl)imidazole at 2.0-A resolution Academic Article
Crystal structure of a fully glycosylated HIV-1 gp120 core reveals a stabilizing role for the glycan at Asn262 Academic Article
Crystal structure of a human aminoacyl-tRNA synthetase cytokine Academic Article
Crystal structure of a human peptidyl-tRNA hydrolase reveals a new fold and suggests basis for a bifunctional activity Academic Article
Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design Academic Article
Crystal structure of a soluble cleaved HIV-1 envelope trimer Academic Article
Crystal structure of an FIV/HIV chimeric protease complexed with the broad-based inhibitor, TL-3 Academic Article
Crystal structure of an alanine-glyoxylate aminotransferase from anabaena sp at 1.70 A resolution reveals a noncovalently linked PLP cofactor Academic Article
Crystal structure of an intact human IgG: antibody asymmetry, flexibility, and a guide for HIV-1 vaccine design Academic Article
Crystal structure of antagonist bound human lysophosphatidic acid receptor 1 Academic Article
Crystal structure of avian aminoimidazole-4-carboxamide ribonucleotide transformylase in complex with a novel non-folate inhibitor identified by virtual ligand screening Academic Article
Crystal structure of botulinum neurotoxin type a in complex with the cell surface co-receptor gt1b - insight into the toxin-neuron interaction Academic Article
Crystal structure of human antibody 2909 reveals conserved features of quaternary structure-specific antibodies that potently neutralize HIV-1 Academic Article
Crystal structure of human carboxylesterase 1 complexed with the Alzheimer's drug tacrine: from binding promiscuity to selective inhibition Academic Article
Crystal structure of human cytochrome p450 2d6 with prinomastat bound Academic Article
Crystal structure of human glyoxalase I--evidence for gene duplication and 3D domain swapping Academic Article
Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue Academic Article
Crystal structure of human ornithine transcarbamylase complexed with carbamoyl phosphate and L-norvaline at 1.9 A resolution Academic Article
Crystal structure of human seryl-tRNA synthetase and Ser-SA complex reveals a molecular lever specific to higher eukaryotes Academic Article
Crystal structure of human toll-like receptor 3 (tlr3) ectodomain Academic Article
Crystal structure of human triggering receptor expressed on myeloid cells 1 (TREM-1) at 1.47 A Academic Article
Crystal structure of human vacuolar protein sorting protein 29 reveals a phosphodiesterase/nuclease-like fold and two protein-protein interaction sites Academic Article
Crystal structure of human vinculin Academic Article
Crystal structure of misoprostol bound to the labor inducer prostaglandin E-2 receptor Academic Article
Crystal structure of mouse cd1: An mhc-like fold with a large hydrophobic binding groove Academic Article
Crystal structure of mouse triggering receptor expressed on myeloid cells 1 (trem-1) at 1.76 Å Academic Article
Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser Academic Article
Crystal structure of tetrameric form of human lysyl-tRNA synthetase: implications for multisynthetase complex formation Academic Article
Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain Academic Article
Crystal structure of the C-terminal domain of mouse TLR9 Academic Article
Crystal structure of the Frizzled 4 receptor in a ligand-free state Academic Article
Crystal structure of the N-terminal domains of the surface cell antigen 4 of Rickettsia Academic Article
Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide Academic Article
Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran Academic Article
Crystal structure of the anti-viral apobec3g catalytic domain and functional implications Academic Article
Crystal structure of the broadly cross-reactive hiv-1-neutralizing fab x5 and fine mapping of its epitope Academic Article
Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine Academic Article
Crystal structure of the complex of brugia malayi cyclophilin and cyclosporin a Academic Article
Crystal structure of the cyclostreptin-tubulin adduct: implications for tubulin activation by taxane-site ligands Academic Article
Crystal structure of the human 4-1BB/4-1BBL complex Academic Article
Crystal structure of the human TRPV2 channel ankyrin repeat domain Academic Article
Crystal structure of the human n-myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor Academic Article
Crystal structure of the il-2 signaling complex: Paradigm for a heterotrimeric cytokine receptor Academic Article
Crystal structure of the lassa virus nucleoprotein-RNA complex reveals a gating mechanism for RNA binding Academic Article
Crystal structure of the murine NK cell-activating receptor NKG2D at 1.95 A Academic Article
Crystal structure of tyrosine hydroxylase at 2.3 Å and its implications for inherited neurodegenerative diseases Academic Article
Crystal structure of tyrosine hydroxylase with bound cofactor analogue and iron at 2.3 Å resolution: Self-hydroxylation of phe300 and the pterin-binding site Academic Article
Crystal structure of vinculin in complex with vinculin binding site 50 (VBS50), the integrin binding site 2 (IBS2) of talin Academic Article
Crystal structure of viral macrophage inflammatory protein i encoded by kaposi's sarcoma-associated herpesvirus at 1.7 a Academic Article
Crystal structure of y34f mutant human mitochondrial manganese superoxide dismutase and the functional role of tyrosine 34 Academic Article
Crystal structure-based virtual screening for fragment-like ligands of the human histamine H(1) receptor Academic Article
Crystal structures and biochemical analyses suggest a unique mechanism and role for human glycyl-tRNA synthetase in Ap4A homeostasis Academic Article
Crystal structures of a quorum-quenching antibody Academic Article
Crystal structures of human GAR Tfase at low and high pH and with substrate β-GAR Academic Article
Crystal structures of human HSP90 alpha-complexed with dihydroxyphenylpyrazoles Academic Article
Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates Academic Article
Crystal structures of human immunodeficiency virus type 1 (hiv-1) neutralizing antibody 2219 in complex with three different v3 peptides reveal a new binding mode for hiv-1 cross-reactivity Academic Article
Crystal structures of human topoisomerase i in covalent and noncovalent complexes with DNA Academic Article
Crystal structures of mouse CD1d-iGb3 complex and its cognate v alpha 14 T cell receptor suggest a model for dual recognition of foreign and self glycolipids Academic Article
Crystal structures of nucleosome core particles in complex with minor groove DNA-binding ligands Academic Article
Crystal structures of protein phosphatase-1 bound to nodularin-R and tautomycin: a novel scaffold for structure-based drug design of serine/threonine phosphatase inhibitors Academic Article
Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain Academic Article
Crystal structures that suggest late development of genetic code components for differentiating aromatic side chains Academic Article
Crystal-structure and mutational analysis of human uracil-DNA glycosylase - structural basis for specificity and catalysis Academic Article
Crystal-structure of human uracil-DNA glycosylase in complex with a protein inhibitor - protein mimicry of DNA Academic Article
Crystal-structure of murine cyclophilin-c complexed with immunosuppressive drug cyclosporine-a Academic Article
Crystal-structure of the human cell-cycle protein ckshs1 - single-domain fold with similarity to kinase n-lobe domain Academic Article
Crystallization and preliminary X-ray analysis of a native human tRNA synthetase whose allelic variants are associated with Charcot-Marie-Tooth disease Academic Article
Crystallization and preliminary X-ray analysis of human carbonic anhydrase III Academic Article
Crystallization and preliminary X-ray diffraction analysis of human adenovirus Academic Article
Crystallization and preliminary crystallographic study of human ckshs1 - a cell-cycle regulatory protein Academic Article
Crystallization and preliminary structure determination of an intact human immunoglobulin, b12: An antibody that broadly neutralizes primary isolates of HIV-1 Academic Article
Crystallization and preliminary-x-ray analysis of the cytoplasmic domain of human erythrocyte band-3 Academic Article
Crystallization and preliminary-x-ray diffraction studies of a complex between interleukin-2 and a soluble form of the p55 component of the high-affinity interleukin-2 receptor Academic Article
Crystallization of GST2, a human class alpha glutathione transferase Academic Article
Crystallization of HLA-DR4 fused to an immunodominant collagen ll peptide implicated in rheumatoid arthritis Academic Article
Crystallization of membrane proteins in lipidic mesophases Academic Article
Crystallization of trimeric recombinant human-tumor necrosis factor (cachectin) Academic Article
Crystallization studies of glycosylated and unglycosylated human recombinant interleukin-2 Academic Article
Crystallizing membrane proteins using lipidic mesophases Academic Article
Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 Å resolution Academic Article
Crystallographic and biochemical analysis of cocaine-degrading antibody l5a10 Academic Article
Crystallographic and computational analyses of AUUCU repeating RNA that causes spinocerebellar ataxia type 10 (SCA10) Academic Article
Crystallographic characterization of recombinant human CuZn superoxide-dismutase Academic Article
Crystallographic fragment-based drug discovery: use of a brominated fragment library targeting HIV protease Academic Article
Crystallographic identification of lipid as an integral component of the epitope of HIV broadly neutralizing antibody 4E10 Academic Article
Crystallographic studies of bovine beta-2-microglobulin Academic Article
Crystallohydrodynamics for solving the hydration problem for multi-domain proteins: Open physiological conformations for human IgG Academic Article
Csf beta-endorphins in childhood neuropsychiatric disorders Academic Article
CtIP maintains stability at common fragile sites and inverted repeats by end resection-independent endonuclease activity Academic Article
CtIP protein dimerization is critical for its recruitment to chromosomal DNA double-stranded breaks Academic Article
Cta1-dd adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization Academic Article
Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination Academic Article
Curation of the mammalian palmitoylome indicates a pivotal role for palmitoylation in diseases and disorders of the nervous system and cancers Academic Article
Curing a viral infection by targeting the host: The example of cyclophilin inhibitors Academic Article
Current V3 genotyping algorithms are inadequate for predicting X4 co-receptor usage in clinical isolates Academic Article
Current challenges for the creation of effective vaccines against drugs of abuse Academic Article
Current prevalence of asthma-related symptoms in san diego's predominantly hispanic inner-city children Academic Article
Current role of platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes Academic Article
Current status and future prospects for acute myocardial infarction therapy Academic Article
Current status of available standards for quality improvement of assays for detection of autoantibodies to nuclear and intracellular antigens Academic Article
Current strategies for microRNA research Academic Article
Current strategies in antiplatelet therapy - Does identification of risk and adjustment of therapy contribute to more effective, personalized medicine in cardiovascular disease? Academic Article
Current understanding of sepsis Academic Article
Current views on the pathogenesis of systemic lupus-erythematosus Academic Article
Curve-based multivariate distance matrix regression analysis: Application to genetic association analyses involving repeated measures Academic Article
Custom DNA-binding proteins come of age: Polydactyl zinc-finger proteins Academic Article
Custom zinc-finger nucleases for use in human cells Academic Article
Custom-designed synthetic peptide immunoassays for distinguishing hiv type-1 and type-2 infections Academic Article
Cutaneous injection of rantes causes eosinophil recruitment - comparison of nonallergic and allergic human subjects Academic Article
Cutting Edge: CD1a tetramers and dextramers identify human lipopeptide-specific T cells ex vivo Academic Article
Cutting edge: IL-13Rα1 expression in dopaminergic neurons contributes to their oxidative stress-mediated loss following chronic peripheral treatment with lipopolysaccharide Academic Article
Cutting edge: Impaired glycosphingolipid trafficking and NKT cell development in mice lacking Niemann-Pick type C1 protein Academic Article
Cutting edge: association with I kappa B kinase beta regulates the subcellular localization of Homer3 Academic Article
Cvak104 is a novel poly-l-lysine-stimulated kinase that targets the beta 2-subunit of ap2 Academic Article
Cyclic GMP and cGMP-binding phosphodiesterase are required for interleukin-1-induced nitric oxide synthesis in human articular chondrocytes Academic Article
Cyclic and linear oligocarbamate ligands for human thrombin Academic Article
Cyclic immune thrombocytopenia responsive to thrombopoietic growth factor therapy Academic Article
Cyclic marinopyrrole derivatives as disruptors of Mcl-1 and Bcl-x(L) binding to Bim Academic Article
Cyclin B1 is commonly expressed in the cytoplasm of primary human acute myelogenous leukemia cells and serves as a leukemia-associated antigen associated with autoantibody response in a subset of patients Academic Article
Cyclin D1 associates with the TBP-associated factor TAF(II)250 to regulate Sp1-mediated transcription Academic Article
Cyclin D1 suppresses retinoblastoma protein-mediated inhibition of TAFII250 kinase activity Academic Article
Cyclin E deregulation promotes loss of specific genomic regions Academic Article
Cyclin E overexpression impairs progression through mitosis by inhibiting APC(Cdh1) Academic Article
Cyclin E: In mid-cycle Academic Article
Cyclin I is an RS domain protein involved in pre-mRNA splicing Academic Article
Cyclin a-associated kinase-activity is rate-limiting for entrance into s-phase and is negatively regulated in g(1) by p27(kip1) Academic Article
Cyclin d2 in the basal process of neural progenitors is linked to non-equivalent cell fates Academic Article
Cyclin d3 is rate-limiting for the g(1)/s phase transition in fibroblasts Academic Article
Cyclin e dysregulation and chromosomal instability in endometrial cancer Academic Article
Cyclin e-induced s phase without activation of the prb/e2f pathway Academic Article
Cyclin-dependent kinase 12 increases 3' end processing of growth factor-induced c-FOS transcripts Academic Article
Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities Academic Article
Cyclin-dependent kinase subunit (Cks) 1 or Cks2 overexpression overrides the DNA damage response barrier triggered by activated oncoproteins Academic Article
Cyclin-dependent kinase-associated proteins cks1 and cks2 are essential during early embryogenesis and for cell cycle progression in somatic cells Academic Article
Cyclin-dependent kinases 5 template: useful for virtual screening Academic Article
Cyclin-dependent kinases phosphorylate human Cdt1 and induce its degradation Academic Article
Cyclin-e cdk2 and cyclin-a cdk2 kinases associate with p107 and e2f in a temporally distinct manner Academic Article
Cycloheximide and congeners as inhibitors of eukaryotic protein synthesis from endophytic actinomycetes streptomyces sps. Yim56132 and yim56141 Academic Article
Cyclooxygenase-2 inhibitors. 1,5-diarylpyrrol-3-acetic esters with enhanced inhibitory activity toward cyclooxygenase-2 and improved cyclooxygenase-2/cyclooxygenase-1 selectivity Academic Article
Cyclooxygenase-2: Where are we in 2003? Cardiovascular risk and cox-2 inhibitors Academic Article
Cyclophilin A plays distinct roles in human immunodeficiency virus type 1 entry and postentry events, as revealed by spinoculation Academic Article
Cyclophilin A-independent recruitment of NS5A and NS5B into hepatitis C virus replication complexes Academic Article
Cyclophilin and NS5A inhibitors, but not other anti-hepatitis C virus (HCV) agents, preclude HCV-mediated formation of double-membrane-vesicle viral factories Academic Article
Cyclophilin inhibitors Academic Article
Cyclophilin inhibitors for the treatment of HCV infection Academic Article
Cyclophilin inhibitors: A novel class of promising host-targeting anti-HCV agents Academic Article
Cyclophilin inhibitors: An emerging class of therapeutics for the treatment of chronic hepatitis C infection Academic Article
Cyclophilin involvement in the replication of hepatitis C virus and other viruses Academic Article
Cyclosporin-a regulates monocyte macrophage effector functions by affecting instructor t-cells - inhibition of monocyte procoagulant response to allogeneic stimulation Academic Article
Cyclostreptin (FR182877), an antitumor tubulin-polymerizing agent deficient in enhancing tubulin assembly despite its high affinity for the taxoid site Academic Article
Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites Academic Article
Cyclostreptin derivatives specifically target cellular tubulin and further map the paclitaxel site Academic Article
Cyp2c9*3 and *13 alleles significantly affect the pharmacokinetics of irbesartan in healthy korean subjects Academic Article
Cys-X scanning for expansion of active-site residues and modulation of catalytic functions in a glutathione transferase Academic Article
Cys10 mixed disulfides make transthyretin more amyloidogenic under mildly acidic conditions Academic Article
Cysteine cathepsins in the secretory vesicle produce active peptides: cathepsin L generates peptide neurotransmitters and cathepsin B produces beta-amyloid of Alzheimer's disease Academic Article
Cysteine mapping in conformationally distinct kinase nucleotide binding sites: application to the design of selective covalent inhibitors Academic Article
Cysteine modifiers suggest an allosteric inhibitory site on the CAL PDZ domain Academic Article
Cysteine regulation of protein function - as exemplified by NMDA-receptor modulation Academic Article
Cysteine residues are not essential for the catalytic activity of human class Mu glutathione transferase M1a-1a Academic Article
Cysteine-mediated redox signaling: chemistry, biology, and tools for discovery Academic Article
Cysteine-specific chemical proteomics: from target identification to drug discovery Academic Article
Cystic fibrosis in an era of genomically guided therapy Academic Article
Cystic fibrosis therapy: a community ecology perspective Academic Article
Cytochrome P450-mediated bioactivation of the epidermal growth factor receptor inhibitor erlotinib to a reactive electrophile Academic Article
Cytogenetic characterization of B-cell lymphomas from severe combined immunodeficiency disease mice given injections of lymphocytes from Epstein-Barr virus-positive donors Academic Article
Cytokine activation of vascular endothelium. Effects on tissue-type plasminogen activator and type 1 plasminogen activator inhibitor Academic Article
Cytokine gene therapy of cancer using interleukin-12: murine and clinical trials Academic Article
Cytokine gene-therapy with interleukin-2-transduced fibroblasts - effects of il-2 dose on antitumor immunity Academic Article
Cytokine receptor dimerization and activation: prospects for small molecule agonists Academic Article
Cytokine regulation of facilitated glucose transport in human articular chondrocytes Academic Article
Cytokine rescue of p53-dependent apoptosis and cell cycle arrest is mediated by distinct jak kinase signaling pathways Academic Article
Cytokine signals through PI-3 kinase pathway modulate Th17 cytokine production by CCR6+ human memory T cells Academic Article
Cytokine storm plays a direct role in the morbidity and mortality from influenza virus infection and is chemically treatable with a single sphingosine-1-phosphate agonist molecule Academic Article
Cytokine-induced viral purging - role in viral pathogenesis Academic Article
Cytokine-mediated control of viral infections Academic Article
Cytokine-sensitive replication of hepatitis B virus in immortalized mouse hepatocyte cultures Academic Article
Cytokine-stimulated, but not HIV-infected, human monocyte-derived macrophages produce neurotoxic levels of L-cysteine Academic Article
Cytokines and cancer cachexia Academic Article
Cytokines and t cell homeostasis Academic Article
Cytokines and t-cell homeostasis Academic Article
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Cytokines in neuronal cell types Academic Article
Cytokines in symptomatic asthma airways Academic Article
Cytomegalovirus activates interferon immediate-early response gene expression and an interferon regulatory factor 3-containing interferon-stimulated response element-binding complex Academic Article
Cytomegalovirus infects human-lymphocytes and monocytes - virus expression is restricted to immediate-early gene-products Academic Article
Cytometric comparisons between circulating tumor cells from prostate cancer patients and the prostate-tumor-derived lncap cell line Academic Article
Cytoplasmic domain-mediated dimerizations of toll-like receptor 4 observed by beta-lactamase enzyme fragment complementation Academic Article
Cytoprotective protein C pathways and implications for stroke and neurological disorders Academic Article
Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes Academic Article
Cytoprotective-selective activated protein C attenuates pseudomonas aeruginosa-induced lung injury in mice Academic Article
Cytoprotective-selective activated protein C therapy for ischaemic stroke Academic Article
Cytoskeletal components of an invasion machine: the apical complex of Toxoplasma gondii Academic Article
Cytosol- and clathrin-dependent stimulation of endocytosis in vitro by purified adaptors Academic Article
Cytotoxic T cells and viral hepatitis Academic Article
Cytotoxic T lymphocyte response to hepatitis C virus-derived peptides containing the HLA A2.1 binding motif Academic Article
Cytotoxic T lymphocyte responsiveness after resolution of chronic hepatitis B virus infection Academic Article
Cytotoxic T lymphocytes recognize an HLA-A2-restricted epitope within the hepatitis B virus nucleocapsid antigen Academic Article
Cytotoxic T-lymphocyte response to a wild-type hepatitis-B virus epitope in patients chronically infected by variant viruses carrying substitutions within the epitope Academic Article
Cytotoxic lymphocytes generated in vivo with acute measles virus infection Academic Article
Cytotoxicity of a Ti(IV) compound is independent of serum proteins Academic Article
Cytotoxicity of quantum dots used for in vitro cellular labeling: role of QD surface ligand, delivery modality, cell type, and direct comparison to organic fluorophores Academic Article
D-4 dopamine receptor high-resolution structures enable the discovery of selective agonists Academic Article
D-Ornithine coopts pyrrolysine biosynthesis to make and insert pyrroline-carboxy-lysine Academic Article
D-amino acid oxidase activator gene (daoa) variation affects cerebrospinal fluid homovanillic acid concentrations in healthy caucasians Academic Article
D18G transthyretin is monomeric, aggregation prone, and not detectable in plasma and cerebrospinal fluid: a prescription for central nervous system amyloidosis? Academic Article
D471G mutation in LCMV-NP affects its ability to self-associate and results in a dominant negative effect in viral RNA synthesis Academic Article
DAF-12-dependent rescue of dauer formation in Caenorhabditis elegans by (25S)-cholestenoic acid Academic Article
DAMB, a novel dopamine receptor expressed specifically in Drosophila mushroom bodies Academic Article
DAP-kinase loss of expression in various carcinoma and B-cell lymphoma cell lines: Possible implications for role as tumor suppressor gene Academic Article
DAP-kinase participates in TNF-alpha- and Fas-induced apoptosis and its function requires the death domain Academic Article
DCAF4, a novel gene associated with leucocyte telomere length Academic Article
DDA3 recruits microtubule depolymerase Kif2a to spindle poles and controls spindle dynamics and mitotic chromosome movement Academic Article
DDAVP enhances platelet adherence and platelet aggregate growth on human artery subendothelium Academic Article
DDAVP in haemophilia Academic Article
DDX1 is an RNA-dependent ATPase involved in HIV-1 Rev function and virus replication Academic Article
DEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A Academic Article
DICER- and AGO3-dependent generation of retinoic acid-induced DR2 Alu RNAs regulates human stem cell proliferation Academic Article
DISC1 regulates trafficking and processing of APP and Aβ generation Academic Article
DISCovery in psychiatric genetics Academic Article
DIx5 homeodomain:DNA complex: structure, binding and effect of mutations related to split hand and foot malformation syndrome Academic Article
DNA arrays: applications and implications for circadian biology Academic Article
DNA binding alters coactivator interaction surfaces of the intact VDR-RXR complex Academic Article
DNA binding and nucleotide flipping by the human DNA repair protein agt Academic Article
DNA binding domain in the replication checkpoint protein Mrc1 of Schizosaccharomyces pombe Academic Article
DNA binding fluorescent proteins for the direct visualization of large DNA molecules Academic Article
DNA binding, nucleotide flipping, and the helix-turn-helix motif in base repair by o-6-alkylguanine-DNA alkyltransferase and its implications for cancer chemotherapy Academic Article
DNA binding-dependent glucocorticoid receptor activity promotes adipogenesis via Kruppel-like factor 15 gene expression Academic Article
DNA damage recognition and repair pathway coordination revealed by the structural biochemistry of DNA repair enzymes Academic Article
DNA damage triggers Golgi dispersal via DNA-PK and GOLPH3 Academic Article
DNA display of PNA-tagged ligands: A versatile strategy to screen libraries and control geometry of multidentate ligands Academic Article
DNA double-strand break repair pathway choice Is directed by distinct MRE11 nuclease activities Academic Article
DNA immunization: Mechanistic studies Academic Article
DNA loops induced by cooperative binding of transcriptional activator proteins and preinitiation complexes Academic Article
DNA methylation analysis of human myoblasts during in vitro myogenic differentiation: de novo methylation of promoters of muscle-related genes and its involvement in transcriptional down-regulation Academic Article
DNA methylation and chromatin structure regulate T cell perforin gene expression Academic Article
DNA methylation fingerprint of neuroblastoma reveals new biological and clinical insights Academic Article
DNA methylation in embryonic stem cells Academic Article
DNA polymerase activity assay using near-infrared fluorescent labeled DNA visualized by acrylamide gel electrophoresis Academic Article
DNA polymerase activity at the single-molecule level Academic Article
DNA repair and global sumoylation are regulated by distinct Ubc9 noncovalent complexes Academic Article
DNA repair is crucial for maintaining hematopoietic stem cell function Academic Article
DNA repair mechanisms for the recognition and removal of damaged DNA bases Academic Article
DNA replication checkpoint Academic Article
DNA replication checkpoint control Academic Article
DNA sequence-specific polyamides alleviate transcription inhibition associated with long GAA.TTC repeats in Friedreich's ataxia Academic Article
DNA vaccination to treat autoimmune diabetes Academic Article
DNA-based vaccines activate innate and adaptive antitumor immunity by engaging the nkg2d receptor Academic Article
DNA-binding property of Sm nuclear antigen Academic Article
DNA-binding proteins in human-serum Academic Article
DNA-bound structures and mutants reveal abasic DNA binding by ape1 DNA repair and coordination Academic Article
DNA-dependent protein kinase inhibitors as drug candidates for the treatment of cancer Academic Article
DNA-repair proteins Academic Article
DNase I inhibits a late phase of reactive oxygen species production in neutrophils Academic Article
DOLORS: versatile strategy for internal labeling and domain localization in electron microscopy Academic Article
DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis Academic Article
DUB-resistant ubiquitin to survey ubiquitination switches in mammalian cells Academic Article
DUBs, the regulation of cell identity and disease Academic Article
DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes Academic Article
Daily eating patterns and their impact on health and disease Academic Article
Damage to the bases in DNA induced by stimulated human neutrophils Academic Article
Daring to learn from humanized mice Academic Article
Database searching using mass spectrometry data Academic Article
Dax1 mutations map to putative structural domains in a deduced three-dimensional model Academic Article
Dbf4 is direct downstream target of ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related (ATR) protein to regulate intra-S-phase checkpoint Academic Article
De novo KCNB1 mutations in epileptic encephalopathy Academic Article
De novo identification of VRC01 class HIV-1-neutralizing antibodies by next-generation sequencing of B-cell transcripts Academic Article
De novo identification of tumor-specific internalizing human antibody-receptor pairs by phage-display methods Academic Article
De novo kidney transplantation without use of calcineurin inhibitors preserves renal structure and function at two years Academic Article
De novo-designed enzymes as small-molecule-regulated fluorescence imaging tags and fluorescent reporters Academic Article
De-novo humoral immune responses to cancer-associated autoantigens during transition from chronic liver disease to hepatocellular carcinoma Academic Article
Death and nonfatal reinfarction within the first 24 hours after presentation with an acute coronary syndrome: Experience from gusto-iib Academic Article
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Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function Academic Article
Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis Academic Article
Death-associated proteins: from gene identification to the analysis of their apoptotic and tumour suppressive functions Academic Article
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Deciphering the chromatin landscape induced around DNA double strand breaks Academic Article
Deciphering the interaction of the corticotropin-releasing factor and serotonin brain systems in anxiety-related disorders Academic Article
Decoding arenavirus pathogenesis: Essential roles for alpha-dystroglycan-virus interactions and the immune response Academic Article
Decoding human cytomegalovirus Academic Article
Deconstructing schizophrenia: An overview of the use of endophenotypes in order to understand a complex disorder Academic Article
Deconvoluting post-transplant immunity: Cell subset-specific mapping reveals pathways for activation and expansion of memory t, monocytes and b cells Academic Article
Decrease in measles virus-specific cd4 t cell memory in vaccinated subjects Academic Article
Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression, and apoptosis in mice lacking fatty acid amide hydrolase Academic Article
Decreased cure and increased recurrence rates for Clostridium difficile infection caused by the epidemic C. difficile BI strain Academic Article
Decreased expression of NMDA receptor-associated proteins in frontal cortex of elderly patients with schizophrenia Academic Article
Decreased frequency of rearrangement due to the synergistic effect of nucleotide changes in the heptamer and nonamer of the recombination signal sequence of the V kappa gene A2B, which is associated with increased susceptibility of navajos to haemophilus influenzae type B disease Academic Article
Decreased glutathione and elevated hair mercury levels are associated with nutritional deficiency-based autism in Oman Academic Article
Decreased insulin production, elevated growth hormone levels, and glucose intolerance in liver disease Academic Article
Decreased knee adduction moment does not guarantee decreased medial contact force during gait Academic Article
Decreased perihematomal edema in thrombolysis-related intracerebral hemorrhage compared with spontaneous intracerebral hemorrhage Academic Article
Decreased plasma levels of protein S in well-controlled type I diabetes mellitus Academic Article
Decreased plasma sensitivity to activated protein C by oral contraceptives is associated with decreases in plasma glucosylceramide Academic Article
Decreased production of nitric oxide by human neutrophils during septic multiple organ dysfunction syndrome. Comparison with endotoxin and cytokine effects on normal cells Academic Article
Deep interactome profiling of membrane proteins by co-interacting protein identification technology Academic Article
Deep mutational scanning: a new style of protein science Academic Article
Deep nuclear invaginations are linked to cytoskeletal filaments - integrated bioimaging of epithelial cells in 3D culture Academic Article
Deep sequencing of protease inhibitor resistant HIV patient isolates reveals patterns of correlated mutations in Gag and protease Academic Article
Defective Th1 cytokine gene transcription in CD4(+) and CD8(+) T cells from wiskott-aldrich syndrome patients Academic Article
Defective dimerization of von Willebrand factor subunits due to a Cys -> Arg mutation in type IID von Willebrand disease Academic Article
Defective transport of the obesity mutant PC1/3 N222D contributes to loss of function Academic Article
Defects in RGS9 or its anchor protein R9AP in patients with slow photoreceptor deactivation Academic Article
Defects in deletional tolerance of CD8+ T cells in autoimmune diabetes Academic Article
Defects in the acquisition of CD8 T cell effector function after priming with tumor or soluble antigen can be overcome by the addition of an OX40 agonist Academic Article
Defensive spiroketals from Asceles glaber (Phasmatodea): absolute configuration and effects on ants and mosquitoes Academic Article
Deficiencies in tRNA synthetase editing activity cause cardioproteinopathy Academic Article
Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances Academic Article
Deficiency of factor-XII-dependent plasminogen proactivator in prekallikrein-deficient plasma Academic Article
Deficiency of lrp8 in mice is associated with altered platelet function and prolonged time for in vivo thrombosis Academic Article
Deficiency of protein-C in congenital thrombotic disease Academic Article
Defined and scalable differentiation of human oligodendrocyte precursors from pluripotent stem cells in a 3D culture system Academic Article
Defining CD4 T cell memory by the epigenetic landscape of CpG DNA methylation Academic Article
Defining HIV-1 protease substrate selectivity Academic Article
Defining RNA motif-aminoglycoside interactions via two-dimensional combinatorial screening and structure-activity relationships through sequencing Academic Article
Defining actin filament length in striated muscle: rulers and caps or dynamic stability? Academic Article
Defining antibody-antigen recognition: towards engineered antibodies and epitopes Academic Article
Defining estrogenic mechanisms of bisphenol A analogs through high throughput microscopy-based contextual assays Academic Article
Defining parameters for successful immunocytotherapy of persistent viral infection Academic Article
Defining the appropriate threshold of creatine kinase elevation after percutaneous coronary interventions Academic Article
Defining the communication between agonist and coactivator binding in the retinoid X receptor alpha ligand binding domain Academic Article
Defining the conformational features of anchorless, poorly neuroinvasive prions Academic Article
Defining the metabolome: size, flux, and regulation Academic Article
Defining the mode of action of tetramic acid antibacterials derived from Pseudomonas aeruginosa quorum sensing signals Academic Article
Defining the optimal activated clotting time during percutaneous coronary intervention - aggregate results from 6 randomized, controlled trials Academic Article
Defining the pathogenic involvement of desmoglein 4 in pemphigus and staphylococcal scalded skin syndrome Academic Article
Defining the risks of mesenchymal stromal cell therapy Academic Article
Defining the role of oxygen tension in human neural progenitor fate Academic Article
Definition of a minimal optimal cytotoxic T-cell epitope within the hepatitis B virus nucleocapsid protein Academic Article
Definition of the sites of interaction between the protein tyrosine phosphatase SHP-1 and CD22 Academic Article
Degeneracy and complexity in biological systems Academic Article
Degenerate immunogenicity of an HLA-A2-restricted hepatitis B virus nucleocapsid cytotoxic T-lymphocyte epitope that is also presented by HLA-B51 Academic Article
Degradable conjugates from oxanorbornadiene reagents Academic Article
Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death Academic Article
Degradation, foraging, and depletion of mucus sialoglycans by the vagina-adapted Actinobacterium Gardnerella vaginalis Academic Article
Dehydrated hereditary stomatocytosis linked to gain-of-function mutations in mechanically activated PIEZO1 ion channels Academic Article
Deimination of linker histones links neutrophil extracellular trap release with autoantibodies in systemic autoimmunity Academic Article
Delayed and accelerated aging share common longevity assurance mechanisms Academic Article
Deletion mutants of human interleukin 1β with significantly reduced agonist properties: Search for the agonist/antagonist switch in ligands to the interleukin 1 receptors Academic Article
Deletion of IgG-switched autoreactive B cells and defects in Fas(lpr) lupus mice Academic Article
Deletion of amino acids glu146 -> arg160 in human apolipoprotein a-i (apoa-i-seattle) alters lecithin : Cholesterol acyltransferase activity and recruitment of cell phospholipid Academic Article
Deletion of nef slows but does not prevent CD4-positive T-cell depletion in human immunodeficiency virus type 1-infected human-PBL-SCID mice Academic Article
Deletions linked to TP53 loss drive cancer through p53-independent mechanisms Academic Article
Deletions within the 5 ' utr of coxsackievirus b3: Consequences for virus translation and replication Academic Article
Delineating the susceptibility of botulinum neurotoxins to denaturation through thermal effects Academic Article
Delineation of 3 classes of cea antigenic determinants - identification of membrane-associated cea as an independent species of cea Academic Article
Delineation of suppressor and helper activity within the okt4-defined lymphocyte-t subset in human newborns Academic Article
Delineation of the peptide binding site of the human galanin receptor Academic Article
Delivering quantum dot-peptide bioconjugates to the cellular cytosol: escaping from the endolysosomal system Academic Article
Delivering the kiss of death: Progress on understanding how perforin works Academic Article
Delivery of proteases in aqueous two-phase systems enables direct purification of stem cell colonies from feeder cell co-cultures for differentiation into functional cardiomyocytes Academic Article
Delta-9,11 modification of glucocorticoids dissociates nuclear factor-κB inhibitory efficacy from glucocorticoid response element-associated side effects Academic Article
Dementia associated with the acquired immunodeficiency syndrome Academic Article
Demonstration of circulating immune complexes in Sjögren's syndrome Academic Article
Demonstration of functional similarity of proposed biosimilar ABP 501 to adalimumab Academic Article
Denaturant-induced stimulation of the beta-migrating plasminogen activator inhibitor in endothelial cells and serum Academic Article
Denaturation of dsdna by p53: Fluorescence correlation spectroscopy study Academic Article
Dendritic arbor development and synaptogenesis Academic Article
Dendritic cell inhibition: Memoirs from immunosuppressive viruses Academic Article
Dendritic cell-secreted cytotoxic T-lymphocyte-associated protein-4 regulates the T-cell response by downmodulating bystander surface B7 Academic Article
Dendritic cells transduced with an adenovirus vector encoding Epstein-Barr virus latent membrane protein 2B: A new modality for vaccination Academic Article
Dendritic epidermal t-cell activation Academic Article
Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin Academic Article
Denovo refractory ventricular tachyarrhythmias after coronary revascularization Academic Article
Dense array of spikes on HIV-1 virion particles Academic Article
Dental caries and microbial acid production in twins Academic Article
Dental caries pathogenicity: A genomic and metagenomic perspective Academic Article
Dentin conditioning codetermines cell fate in regenerative endodontics Academic Article
Deoxybonucleic acid (DNA) and antibodies to DNA in the serum of patients with systemic lupus erythematosus Academic Article
Deoxyribonucleic acid antibody: a method to detect its primary interaction with deoxyribonucleic acid Academic Article
Dependence of platelet thrombus stability on sustained glycoprotein IIb/IIIa activation through adenosine 5'-diphosphate receptor stimulation and cyclic calcium signaling Academic Article
Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors Academic Article
Depletion of calcium from the lumen of endoplasmic-reticulum reversibly inhibits passive diffusion and signal-mediated transport into the nucleus Academic Article
Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress Academic Article
Depletion of neutrophils blocks the recruitment of antigen-nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus-specific cytotoxic T lymphocytes Academic Article
Depressed platelet status in an elderly patient with hemorrhagic stroke after thrombolysis for acute myocardial infarction Academic Article
Depression and stimulant dependence - neurobiology and pharmacotherapy Academic Article
Depression modulates pruritus perception - a study of pruritus in psoriasis, atopic-dermatitis, and chronic idiopathic urticaria Academic Article
Depression symptoms associated with cannabis dependence in an adolescent American Indian community sample Academic Article
Deregulated ERK1/2 MAP kinase signaling promotes aneuploidy by a Fbxw7β-Aurora A pathway Academic Article
Deregulated cyclin e induces chromosome instability Academic Article
Deregulation of cyclin e in human cells interferes with prereplication complex assembly Academic Article
Deregulation of the c-myc and n-myc genes in transformed cells Academic Article
Derivation and characterization of a UCP1 reporter human ES cell line Academic Article
Derivation and characterization of a simian immunodeficiency virus SIVmac239 variant with tropism for CXCR4 Academic Article
Derivation and validation of a simple clinical bedside score (ATLAS) for Clostridium difficile infection which predicts response to therapy Academic Article
Derivation of HLA-A11/Kb transgenic mice: functional CTL repertoire and recognition of human A11-restricted CTL epitopes Academic Article
Derivation of a retinoid x receptor scaffold from peroxisome proliferator-activated receptor gamma ligand 1-di(1h-indol-3-yl)methyl-4-trifluoromethylbenzene Academic Article
Derivatives of (3S)-N-(biphenyl-2-ylmethyl)pyrrolidin-3-amine as selective noradrenaline reuptake inhibitors: Reducing P-gp mediated efflux by modulation of H-bond acceptor capacity Academic Article
Derivatives of 4-amino-3,6-disulfonato-1,8-naphthalimide inhibit reverse-transcriptase and suppress human and feline immunodeficiency virus expression in cultured-cells Academic Article
Deriving four functional anti-HIV siRNAs from a single Pol III-generated transcript comprising two adjacent long hairpin RNA precursors Academic Article
Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease Academic Article
Dermatan sulfate and LMW heparin enhance the anticoagulant action of activated protein C Academic Article
Descending command systems for the initiation of locomotion in mammals Academic Article
Description of the data from the collaborative study on the genetics of alcoholism (coga) and single-nucleotide polymorphism genotyping for genetic analysis workshop 14 Academic Article
Desensitization and endocytosis mechanisms of ghrelin-activated growth hormone secretagogue receptor 1a Academic Article
Desensitization of G protein-coupled receptors and neuronal functions Academic Article
Desensitization of the beta-adrenergic response in human brown adipocytes Academic Article
Desflurane increases brain tissue oxygenation and ph Academic Article
Design and characterization of a DNA-encoded, voltage-sensitive fluorescent protein Academic Article
Design and characterization of an active site selective caspase-3 transnitrosating agent Academic Article
Design and characterization of epitope-scaffold immunogens that present the motavizumab epitope from respiratory syncytial virus Academic Article
Design and characterization of stabilized derivatives of human cd4d12 and cd4d1 Academic Article
Design and discovery of N-(2-Methyl-5 '-morpholino-6 '-((tetrahydro-2H-pyran-4-yl)oxy)- 3,3 '-bipyridin -5-yl)-3-(trifluoromethyl)benzamide (RAF709): a potent, selective, and efficacious RAF inhibitor targeting RAS mutant cancers Academic Article
Design and evaluation of novel 8-oxo-pyridopyrimidine Jak1/2 inhibitors Academic Article
Design and evolution of new catalytic activity with an existing protein scaffold Academic Article
Design and simulation of a neutron source based on an electron linear accelerator for bnct of skin melanoma Academic Article
Design and structure of an engineered disulfide-stabilized influenza virus hemagglutinin trimer Academic Article
Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens Academic Article
Design and synthesis of 2-amino-isoxazolopyridines as Polo-like kinase inhibitors Academic Article
Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors Academic Article
Design and synthesis of 2-substituted-5-(4-trifluoromethylphenyl-sulphonamido)benzoxazole derivatives as human GST P1-1 inhibitors Academic Article
Design and synthesis of AX4697, a bisindolylmaleimide exo-affinity probe that labels protein kinase C alpha and beta Academic Article
Design and synthesis of Hsp90 inhibitors: Exploring the SAR of Sansalvamide A derivatives Academic Article
Design and synthesis of a biaryl series as inhibitors for the bromodomains of CBP/P300 Academic Article
Design and synthesis of a cell-permeable synthetic transcription factor mimic Academic Article
Design and synthesis of alpha-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis Academic Article
Design and synthesis of conformationally constrained 3-(n-alkylamino)propylphosphonic acids as potent agonists of sphingosine-1-phosphate (s1p) receptors Academic Article
Design and synthesis of highly potent and isoform selective JNK3 inhibitors: SAR studies on aminopyrazole derivatives Academic Article
Design and synthesis of novel hybrid benzamide-peptide histone deacetylase inhibitors Academic Article
Design and synthesis of potent, selective, and orally bioavailable tetrasubstituted imidazole inhibitors of p38 mitogen-activated protein kinase Academic Article
Design and synthesis of reboxetine analogs morpholine derivatives as selective norepinephrine reuptake inhibitors Academic Article
Design of RNAi hairpins for mutation-specific silencing of ataxin-7 and correction of a SCA7 phenotype Academic Article
Design of a Janus kinase 3 (JAK3) specific inhibitor 1-(2s,5R)-5-((7H-pyrrolo 2,3-d pyrimidin-4-yl)amino)-2-methylpiperidin-1 -y1)prop-2-en-1-one (PF-06651600) allowing for the interrogation of JAK3 signaling in humans Academic Article
Design of a bioactive small molecule that targets the myotonic dystrophy type 1 RNA via an RNA motif-ligand database and chemical similarity searching Academic Article
Design of a monomeric human glutathione transferase gstp1, a structurally stable but catalytically inactive protein Academic Article
Design of a potent CD1d-binding NKT cell ligand as a vaccine adjuvant Academic Article
Design of multivalent galactosyl carborane as a targeting specific agent for potential application to boron neutron capture therapy Academic Article
Design of peptide imaging agents for whole-body and intraoperative molecular imaging Academic Article
Design of polydactyl zinc-finger proteins for unique addressing within complex genomes Academic Article
Design of potent and proteolytically stable oxyntomodulin analogs Academic Article
Design of potent and selective 2-aminobenzimidazole-based p38 alpha MAP kinase inhibitors with excellent in vivo efficacy Academic Article
Design of specific mechanism-based inactivators of hepatic and adrenal microsomal cytochromes-P-450 responsible for progesterone 21-hydroxylation Academic Article
Design of the blockade of the glycoprotein iib/iiia receptor to avoid vascular occlusion (bravo) trial Academic Article
Design of two chimaeric human-rat class alpha glutathione transferases for probing the contribution of C-terminal segments of protein structure to the catalytic properties Academic Article
Design, synthesis and SAR analysis of novel potent and selective small molecule antagonists of NPBWR1 (GPR7) Academic Article
Design, synthesis and activity of light deactivatable microRNA inhibitor Academic Article
Design, synthesis and bioactions of novel stable mimetics of lipoxins and aspirin-triggered lipoxins Academic Article
Design, synthesis and biological evaluation of 10-CF3CO-DDACTHF analogues and derivatives as inhibitors of GAR Tfase and the de novo purine biosynthetic pathway Academic Article
Design, synthesis and biological evaluation of artemisinin derivatives containing fluorine atoms as anticancer agents Academic Article
Design, synthesis and biological evaluation of nonpeptide integrin antagonists Academic Article
Design, synthesis and biological evaluation of novel 4-phenylisoquinolinone BET bromodomain inhibitors Academic Article
Design, synthesis and biological evaluation of novel pyrenyl derivatives as anticancer agents Academic Article
Design, synthesis and biological-activity of protaxols Academic Article
Design, synthesis and evaluation of 2,5-diketopiperazines as inhibitors of the MDM2-p53 interaction Academic Article
Design, synthesis and evaluation of a PLG tripeptidomimetic based on a pyridine scaffold Academic Article
Design, synthesis and structure-activity relationships of novel biarylamine-based Met kinase inhibitors Academic Article
Design, synthesis, and activity of HDAC inhibitors with a N-formyl hydroxylamine head group Academic Article
Design, synthesis, and biological activities of closantel analogues: structural promiscuity and its impact on Onchocerca volvulus Academic Article
Design, synthesis, and biological activity of substrate competitive SMYD2 inhibitors Academic Article
Design, synthesis, and biological evaluation of 10-methanesulfonyl-DDACTHF, 10-methanesulfonyl-5-DACTHF, and 10-methylthio-DDACTHF as potent inhibitors of GAR Tfase and the de novo purine biosynthetic pathway Academic Article
Design, synthesis, and biological evaluation of 3-[4-(2-hydroxyethyl)piperazin-1-yl]-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one, a potent, orally active, brain penetrant inhibitor of phosphodiesterase 5 (PDE5) Academic Article
Design, synthesis, and biological evaluation of a biyouyanagin compound library Academic Article
Design, synthesis, and biological evaluation of novel aminopyrimidinylisoindolines as AXL kinase inhibitors Academic Article
Design, synthesis, and biological evaluation of peptidomimetic inhibitors of factor XIa as novel anticoagulants Academic Article
Design, synthesis, and biological evaluation of simplified alpha-keto heterocycle, trifluoromethyl ketone, and formyl substituted folate analogues as potential inhibitors of GAR transformylase and AICAR transformylase Academic Article
Design, synthesis, and biological properties of highly potent epothilone b analogues Academic Article
Design, synthesis, and evaluation of an α-helix mimetic library targeting protein-protein interactions Academic Article
Design, synthesis, and evaluation of novel 3,6-diaryl-4-aminoalkoxyquinolines as selective agonists of somatostatin receptor subtype 2 Academic Article
Design, synthesis, and evaluation of oxazole transthyretin amyloidogenesis inhibitors Academic Article
Design, synthesis, and evaluation of phe-gly mimetics: Heterocyclic building blocks for pseudopeptides Academic Article
Design, synthesis, and kinetic characterization of protein N-terminal acetyltransferase inhibitors Academic Article
Design, synthesis, and pharmacological evaluation of a novel series of pyridopyrazine-1,6-dione γ-secretase modulators Academic Article
Design, synthesis, and pharmacological evaluation of azetedine and pyrrolidine derivatives as dual norepinephrine reuptake inhibitors and 5-HT1A partial agonists Academic Article
Design, synthesis, and pharmacological evaluation of phenoxy pyridyl derivatives as dual norepinephrine reuptake inhibitors and 5-HT1A partial agonists Academic Article
Design, synthesis, and structure-activity-relationship of phenyl imidazoles as potent Smoothened antagonists Academic Article
Design, synthesis, and validation of a β-turn mimetic library targeting protein-protein and peptide-receptor interactions Academic Article
Design, synthesis, biological evaluation, and structural characterization of potent histone deacetylase inhibitors based on cyclic alpha/beta-tetrapeptide architectures Academic Article
Design, synthesis, enzyme-inhibitory activity, and effect on human cancer cells of a novel series of Jumonji domain-containing protein 2 histone demethylase inhibitors Academic Article
Designed enediynes - a new class of DNA-cleaving molecules with potent and selective anticancer activity Academic Article
Designed replacement of an internal hydration water molecule in bpti - structural and functional implications of a glycine-to-serine mutation Academic Article
Designer enediynes generate DNA breaks, interstrand cross-links, or both, with concomitant changes in the regulation of DNA damage responses Academic Article
Designing a broad-spectrum integrative approach for cancer prevention and treatment Academic Article
Designing arenaviral vaccines Academic Article
Designing facial amphiphiles for the stabilization of integral membrane proteins Academic Article
Desipramine treatment of alcoholism Academic Article
Destabilization of Ca2+-free gelsolin may not be responsible for proteolysis in Familial Amyloidosis of Finnish Type Academic Article
Destruction of the locus coeruleus or the dorsal ne bundle does not alter the release of punished responding by ethanol and chlordiazepoxide Academic Article
Detailed characterization of the peptide binding specificity of five common Patr class I MHC molecules Academic Article
Detailed mechanisms of the inactivation of factor viiia by activated protein c in the presence of its cofactors, protein s and factor v Academic Article
Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis Academic Article
Detecting and quantifying multiple proteins in clinical samples in high-throughput using antibody microarrays Academic Article
Detecting expression of 5T4 in CTCs and tumor samples from NSCLC patients Academic Article
Detecting genetic variation in microarray expression data Academic Article
Detection and characterization of low abundance cellular proteins that specifically increase upon loss of the metastatic phenotype Academic Article
Detection and isolation of dendritic cells using Lewis X-functionalized magnetic nanoparticles Academic Article
Detection and partial characterization of an inhibitor of plasminogen activator in human platelets Academic Article
Detection and partial characterization of circulating immune-complexes with solid-phase anti-c3 Academic Article
Detection and quantification of plasma amyloid-β by selected reaction monitoring mass spectrometry Academic Article
Detection and quantitation of cleaved and uncleaved high molecular weight kininogen in plasma by ligand blotting with radiolabeled plasma prekallikrein or factor XI Academic Article
Detection and typing of herpes simplex viruses by using recombinant immunoglobulin fragments produced in bacteria Academic Article
Detection of 2 apolipoprotein-b species (apobc and apobg) by a monoclonal-antibody Academic Article
Detection of a 140 KDA nucleolar protein with an anti-PCNA autoantibody Academic Article
Detection of a nucleolar 7-2 ribonucleoprotein and a cytoplasmic 8-2 ribonucleoprotein with autoantibodies from patients with scleroderma Academic Article
Detection of a ternary complex of nf-kappa b and i kappa b alpha with DNA provides insights into how i kappa b alpha removes nf-kappa b from transcription sites Academic Article
Detection of active kallikrein in induced blister fluids of hereditary angioedema patients Academic Article
Detection of alkynes via click chemistry with a brominated coumarin azide by simultaneous fluorescence and isotopic signatures in mass spectrometry Academic Article
Detection of antibodies against the four subtypes of ebola virus in sera from any species using a novel antibody-phage indicator assay Academic Article
Detection of apoptosis in cartilage in situ and in isolated chondrocytes Academic Article
Detection of autoantibodies to recombinant mitochondrial proteins in patients with primary biliary-cirrhosis Academic Article
Detection of borna disease virus (bdv) antibodies and bdv rna in psychiatric patients: Evidence for high sequence conservation of human blood-derived bdv rna Academic Article
Detection of borna disease virus antigen and rna in human autopsy brain samples from neuropsychiatric patients Academic Article
Detection of both type 1 and type 2 plasminogen activator inhibitors in human cells Academic Article
Detection of c-myc gene expression in nasopharyngeal carcinoma by nonradioactive in situ hybridization and immunohistochemistry Academic Article
Detection of carbohydrates and steroids by cation-enhanced nanostructure-initiator mass spectrometry (NIMS) for biofluid analysis and tissue imaging Academic Article
Detection of circulating immune-complexes in patients with glomerulonephritis Academic Article
Detection of complement activation by counterimmunoelectrophoresis (CIE) Academic Article
Detection of complete molar pregnancy by single-nucleotide polymorphism-based non-invasive prenatal testing Academic Article
Detection of cytomegalovirus nucleic-acid sequences in pancreas in type-2 diabetes Academic Article
Detection of ganglioside gd2 in tumor-tissues and sera of neuro-blastoma patients Academic Article
Detection of genetic-heterogeneity for complex quantitative phenotypes Academic Article
Detection of human cytomegalo-virus in peripheral-blood lymphocytes in a natural infection Academic Article
Detection of human cytomegalovirus in clinical specimens by DNA-DNA hybridization Academic Article
Detection of human α-L-Fucosidase by a quinone methide-generating probe: enhanced activities in response to Helicobacter pylori Infection Academic Article
Detection of immune complexes: Techniques and implications Academic Article
Detection of in vitro and in vivo cleavage of high molecular weight kininogen in human plasma by immunoblotting with monoclonal antibodies Academic Article
Detection of interleukin 1 beta but not tumor necrosis factor-alpha in cerebrospinal fluid of children with aseptic meningitis Academic Article
Detection of low molecular weight derivatives of cyclin e1 is a function of cyclin e1 protein levels in breast cancer Academic Article
Detection of low prevalence somatic mutations in solid tumors with ultra-deep targeted sequencing Academic Article
Detection of low-avidity CD4(+) T cells using recombinant artificial APC: following the antiovalbumin immune response Academic Article
Detection of miRNA in live cells by using templated RuII-catalyzed unmasking of a fluorophore Academic Article
Detection of minority resistance during early HIV-1 infection: natural variation and spurious detection rather than transmission and evolution of multiple viral variants Academic Article
Detection of protein S-sulfhydration by a tag-switch technique Academic Article
Detection of tissue kallikrein in the bronchoalveolar lavage fluid of asthmatic subjects Academic Article
Detection of triploid, molar, and vanishing twin pregnancies by a single-nucleotide polymorphism-based noninvasive prenatal test Academic Article
Determinants flanking the cd4 binding loop modulate macrophage tropism of human immunodeficiency virus type 1 r5 envelopes Academic Article
Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1 Academic Article
Determinants of 2-year outcome after coronary angioplasty in patients with multivessel disease on the basis of comprehensive preprocedural evaluation - implications for patient selection Academic Article
Determinants of cytochrome P4502C8 substrate binding - structures of complexes with montelukast, troglitazone, felodipine, and 9-cis-retinoic acid Academic Article
Determinants of human adipose tissue gene expression: Impact of diet, sex, metabolic status, and cis genetic regulation Academic Article
Determinants of human immunodeficiency virus type 1 envelope glycoprotein activation by soluble cd4 and monoclonal antibodies Academic Article
Determinants of polyreactivity in a large panel of recombinant human antibodies from hiv-1 infection Academic Article
Determinants of sustained viral suppression in HIV-infected patients with self-reported poor adherence to antiretroviral therapy Academic Article
Determinants of the heme-CO vibrational modes in the H-NOX family Academic Article
Determinants of the need for early acute intervention in patients treated conservatively after thrombolytic therapy for acute myocardial-infarction Academic Article
Determinants of the use of coronary angiography and revascularization after thrombolysis for acute myocardial infarction Academic Article
Determinants of viral clearance and persistence during acute hepatitis C virus infection Academic Article
Determination of N-retinylidene-N-retinylethanolamine (A2E) levels in central and peripheral areas of human retinal pigment epithelium Academic Article
Determination of atomoxetine metabolites in human plasma by liquid chromatography/tandem mass spectrometry and its application to a pharmacokinetic study Academic Article
Determination of clinical and demographic predictors of laboratory-confirmed influenza with subtype analysis Academic Article
Determination of enzymatic source of alanine aminotransferase activity in serum from dogs with liver injury Academic Article
Determination of functional and antigenic protein-C inhibitor and its complexes with activated protein-C in plasma by ELISA's Academic Article
Determination of matrix metalloproteinase activity using biotinylated gelatin Academic Article
Determination of meloxicam in human plasma using a hplc method with uv detection and its application to a pharmacokinetic study Academic Article
Determination of plasma protein-C inhibitor and of 2 activated protein-C-inhibitor complexes in normals and in patients with intravascular coagulation and thrombotic disease Academic Article
Determination of structural models of the complex between the cytoplasmic domain of erythrocyte band 3 and ankyrin-R repeats 13-24 Academic Article
Determination of the number of epsilon-amino groups available for conjugation of effector molecules to monoclonal-antibodies Academic Article
Determination of the von Willebrand's disease antigen (factor VIII-related antigen) in plasma by quantitative immunoelectrophoresis Academic Article
Determination of unbound antiretroviral drug concentrations by a modified ultrafiltration method reveals high variability in the free fraction Academic Article
Determining conserved metabolic biomarkers from a million database queries Academic Article
Determining target engagement in living systems Academic Article
Detoxication of base propenals and other alpha, beta-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferases Academic Article
Detoxication of carcinogenic fjord-region diol epoxides of polycyclic aromatic hydrocarbons by glutathione transferase P1-1 variants and glutathione Academic Article
Detoxification of styrene oxide by human liver glutathione transferase Academic Article
Deuterium-proton exchange on the native wild-type transthyretin tetramer identifies the stable core of the individual subunits and indicates mobility at the subunit interface Academic Article
Developing a vaccine against multiple psychoactive targets: a case study of heroin Academic Article
Developing basic and clinical research on von Willebrand factor and von Willebrand disease Academic Article
Developing master keys to brain pathology, cancer and aging from the structural biology of proteins controlling reactive oxygen species and DNA repair Academic Article
Development and characterization of nonpeptidic small molecule inhibitors of the XIAP/caspase-3 interaction Academic Article
Development and mechanism of γ-secretase modulators for Alzheimer's disease Academic Article
Development and optimization of piperidyl-1,2,3-triazole ureas as selective chemical probes of endocannabinoid biosynthesis Academic Article
Development and regeneration of sensory transduction in auditory hair cells requires functional interaction between cadherin-23 and protocadherin-15 Academic Article
Development and structural analysis of a nanomolar cyclic peptide antagonist for the EphA4 receptor Academic Article
Development and use of clickable activity based protein profiling agents for protein arginine deiminase 4 Academic Article
Development and validation of a broad scheme for prediction of HLA class II restricted T cell epitopes Academic Article
Development and validation of decision rules to guide frequency of monitoring CD4 cell count in HIV-1 infection before starting antiretroviral therap Academic Article
Development of 5N-bicalutamide, a high-affinity reversible covalent antiandrogen Academic Article
Development of 6-substituted indolylquinolinones as potent Chek1 kinase inhibitors Academic Article
Development of GlcNAc-Inspired Iminocyclitiols as Potent and Selective N-Acetyl-beta-Hexosaminidase Inhibitors Academic Article
Development of Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) inhibitors with potent anti-toxoplasma activity Academic Article
Development of a blood-based gene expression algorithm for assessment of obstructive coronary artery disease in non-diabetic patients Academic Article
Development of a cell-based, high-throughput screening assay for ATM kinase inhibitors Academic Article
Development of a high-throughput screening-compatible cell-based functional assay to identify small molecule probes of the galanin 3 receptor (GalR3) Academic Article
Development of a highly potent, novel M(5) positive allosteric modulator (PAM) demonstrating CNS exposure: 1-((1H-indazol-5-yl)sulfoneyl)-N-ethyl-N-(2-(trifluoromethyl)benzyl)pipe ridine-4-carboxamide (ML380) Academic Article
Development of a human antibody cocktail that deploys multiple functions to confer pan-ebolavirus protection Academic Article
Development of a lipopeptide-based therapeutic vaccine to treat chronic HBV infection. I. Induction of a primary cytotoxic T lymphocyte response in humans Academic Article
Development of a liver-targeted siRNA delivery platform with a broad therapeutic window utilizing biodegradable polypeptide-based polymer conjugates Academic Article
Development of a multi-institutional cohort to facilitate cardiovascular disease biomarker validation using existing biorepository samples linked to electronic health records Academic Article
Development of a novel vaccine containing binary toxin for the prevention of clostridium difficile disease with enhanced efficacy against NAP1 strains Academic Article
Development of a phenotypic high-content assay to identify pharmacoperone drugs for the treatment of primary hyperoxaluria type 1 by high-throughput screening Academic Article
Development of a simultaneous analytical method for selected anorectics, methamphetamine, mdma, and their metabolites in hair using lc-ms/ms to prove anorectics abuse Academic Article
Development of activity-based probes for imaging Human α-l-Fucosidases in cells Academic Article
Development of amino-pyrimidine inhibitors of c-Jun N-terminal kinase (JNK): Kinase profiling guided optimization of a 1,2,3-benzotriazole lead Academic Article
Development of an HTS-compatible assay for discovery of ROR alpha modulators using AlphaScreen (r) technology Academic Article
Development of an HTS-compatible assay for the discovery of ASK1 signalosome inhibitors using alphascreen technology Academic Article
Development of an HTS-compatible assay for the discovery of Ulk1 inhibitors Academic Article
Development of an intact cell reporter gene beta-lactamase assay for g protein-coupled receptors for high-throughput screening Academic Article
Development of anti-CD74 antibody-drug conjugates to target glucocorticoids to immune cells Academic Article
Development of antibody surrogates for the treatment of cancers and autoimmune disease Academic Article
Development of antigen-specific helper T cell responses in vivo: antigen-specific Th cell subsets Academic Article
Development of bioorthogonal reactions and their applications in bioconjugation Academic Article
Development of c5a receptor antagonists - differential loss of functional-responses Academic Article
Development of chimeric molecules for recognition and targeting of antigen-specific B cells in pemphigus vulgaris Academic Article
Development of clickable active site-directed photoaffinity probes for γ-secretase Academic Article
Development of comprehensive functional genomic screens to identify novel mediators of osteoarthritis Academic Article
Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors Academic Article
Development of ecdysone-regulated lentiviral vectors Academic Article
Development of factor VIII antibody in haemophilic monozygotic twins. Academic Article
Development of fucosyltransferase and fucosidase inhibitors Academic Article
Development of functional human monoclonal single-chain variable fragment antibody against hiv-1 from human cervical b cells Academic Article
Development of functionally selective, small molecule agonists at kappa opioid receptors Academic Article
Development of gene-based therapies for cartilage repair Academic Article
Development of globo-h cancer vaccine Academic Article
Development of growth hormone secretagogues Academic Article
Development of high throughput screening assays and pilot screen for inhibitors of metalloproteases meprin α and β Academic Article
Development of highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitors with potent antiproliferative properties Academic Article
Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression Academic Article
Development of inhibitors of the PAS-B domain of the HIF-2α transcription factor Academic Article
Development of non-peptide ligands of growth factor receptor-bound protein 2-SRC homology 2 domain using molecular modeling and NMR spectroscopy Academic Article
Development of novel pharmacotherapeutics for tobacco dependence: Progress and future directions Academic Article
Development of novel therapies for hepatitis C Academic Article
Development of oseltamivir phosphonate congeners as anti-influenza agents Academic Article
Development of pegylated forms of recombinant rhodosporidium toruloides phenylalanine ammonia-lyase for the treatment of classical phenylketonuria Academic Article
Development of pharmacotherapies for drug addiction: a Rosetta stone approach Academic Article
Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB Academic Article
Development of proneurogenic, neuroprotective small molecules Academic Article
Development of protein-detecting microarrays and related devices Academic Article
Development of prototype filovirus recombinant antigen immunoassays Academic Article
Development of selective estrogen receptor modulator (SERM)-like activity through an indirect mechanism of estrogen receptor antagonism: Defining the binding mode of 7-oxabicyclo 2.2.1 hept-5-ene scaffold core ligands Academic Article
Development of small-molecule cryptochrome stabilizer derivatives as modulators of the circadian clock Academic Article
Development of small-molecule inhibitors of the group l p21-activated kinases, emerging therapeutic targets in cancer Academic Article
Development of sulfonamide photoaffinity inhibitors for probing cellular γ-secretase Academic Article
Development of tRNA synthetases and connection to genetic code and disease Academic Article
Development of thioquinazolinones, allosteric Chk1 kinase inhibitors Academic Article
Development of trifunctional probes for glycoproteomic analysis Academic Article
Development of viral nanoparticles for efficient intracellular delivery Academic Article
Development of zinc finger domains for recognition of the 5 '-ann-3 ' family of DNA sequences and their use in the construction of artificial transcription factors Academic Article
Development of zinc finger domains for recognition of the 5'-CNN-3' family DNA sequences and their use in the construction of artificial transcription factors Academic Article
Development, validation, and clinical implementation of an assay to measure total antibody response to Naglazyme (galsulfase) Academic Article
Developmental mechanisms patterning thalamocortical projections: Intrinsic, extrinsic and in between Academic Article
Developmental neurobiology: A genetic cheshire cat? Academic Article
Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies Academic Article
Developmental regulation of TREM2 and DAP12 expression in the murine CNS: implications for Nasu-Hakola disease Academic Article
Developmental regulation of Zbu1, a DNA-binding member of the SWI2/SNF2 family Academic Article
Developmental studies of oligodendrocyte precursor cell-migration and their implications for transplantation as therapy for multiple-sclerosis Academic Article
Developments in ghrelin biology and potential clinical relevance Academic Article
Dextran as a generally applicable multivalent scaffold for improving immunoglobulin-binding affinities of peptide and peptidomimetic ligands Academic Article
Dextran sulfate-dependent fibrinolysis in whole human plasma. Academic Article
Dhhc5 protein palmitoylates flotillin-2 and is rapidly degraded on induction of neuronal differentiation in cultured cells Academic Article
Di-acidic motifs in the membrane-distal C termini modulate the transport of angiotensin II receptors from the endoplasmic reticulum to the cell surface Academic Article
Diabetes mellitus and outcome after primary coronary angioplasty for acute myocardial infarction: Lessons from the gusto-iib angioplasty substudy Academic Article
Diabetes mellitus, glycoprotein iib/iiia blockade, and heparin - evidence for a complex interaction in a multicenter trial Academic Article
Diabetic retinopathy should not be a contraindication to thrombolytic therapy for acute myocardial infarction: Review of ocular hemorrhage incidence and location in the gusto-i trial Academic Article
Diabetic vascular complications in long-standing panhypopituitarism with diabetes. A case report Academic Article
Diadem X: Automated 4 dimensional analysis of morphological data Academic Article
Diagnosing and managing unstable angina Academic Article
Diagnosis and treatment of idiopathic thrombocytopenic purpura: recommendations of the American Society of Hematology Academic Article
Diagnosis of aids by using a 12-amino acid peptide representing an immunodominant epitope of the human-immunodeficiency-virus Academic Article
Diagnosis of bovine spongiform encephalopathy and Creutzfeldt-Jakob disease Academic Article
Diagnosis of prostate cancer using differentially expressed genes in stroma Academic Article
Diagnosis of stroke by CPK isoenzymes Academic Article
Diagnosis, prevention, and treatment of catheter-associated urinary tract infection in adults: 2009 international clinical practice guidelines from the infectious diseases society of america Academic Article
Diagnostic criteria for dysthymic disorder Academic Article
Diagnostic efficacy of 6 plasma-proteins in evaluating consumptive coagulopathies - use of receiver operating characteristic curves to compare antithrombin-III, plasminogen, alpha-2-plasmin inhibitor, fibronectin, prothrombin, and protein-C Academic Article
Diazepam metabolism by cDNA-Expressed human 2C p450s: identification of P4502C18 and P4502C19 as low K(M) diazepam N-demethylases Academic Article
Dibromochloropropane and its effect on testicular function in man Academic Article
Dibutyryl cyclic-amp stimulation of a monocyte-like cell-line, u937 - a model for monocyte chemotaxis and fc receptor-related functions Academic Article
Didehydro-Cortistatin A: a new player in HIV-therapy? Academic Article
Dielectrophoresis-based filtration effect and detection of amyloid beta in plasma for Alzheimer's disease diagnosis Academic Article
Diet, behavior and immunity across the lifespan Academic Article
Difference in countries' use of resources and clinical outcome for patients with cardiogenic shock after myocardial infarction: Results from the gusto trial Academic Article
Differences among allelic variants o

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