subject area of

• A genetic determinant that specifically regulates the frequency of hematopoietic stem cells  Academic Article
• A homing mechanism for bone marrow-derived progenitor cell recruitment to the neovasculature  Academic Article
• A non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis  Academic Article
• Aberrant wound healing and tgf-beta production in the autoimmune-prone mrl/+ mouse  Academic Article
• Activation of Rac-1 Rac-2, and Cdc42 by hemopoietic growth factors or cross-linking of the B-lymphocyte receptor for antigen  Academic Article
• Activation of apoptosis associated with enforced myc expression in myeloid progenitor cells is dominant to the suppression of apoptosis by interleukin-3 or erythropoietin  Academic Article
• Acute Trypanosoma cruzi infection is associated with anemia, thrombocytopenia, leukopenia, and bone marrow hypoplasia: reversal by nifurtimox treatment  Academic Article
• Adiposity, dyslipidemia, and insulin resistance in mice with targeted deletion of phospholipid scramblase 3 (plscr3)  Academic Article
• Adult bone marrow-derived stem cells use R-cadherin to target sites of neovascularization in the developing retina  Academic Article
• Alternative splicing of the human cyclin D-binding Myb-like protein (hDMP1) yields a truncated protein isoform that alters macrophage differentiation patterns  Academic Article
• An image-based screen identifies a small molecule regulator of megakaryopoiesis  Academic Article
• Artificial hematopoietic stem cell niche: bioscaffolds to microfluidics to mathematical simulations  Academic Article
• Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells  Academic Article
• Aspp1: A guardian of hematopoietic stem cell integrity  Academic Article
• Asymmetric segregation and self-renewal of hematopoietic stem and progenitor cells with endocytic Ap2a2  Academic Article
• Atherosclerosis in mice is not affected by a reduction in tissue factor expression  Academic Article
• Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis  Academic Article
• Bone marrow-derived cells fail to induce positive selection in thymus reaggregation cultures  Academic Article
• C-myc induces apoptosis and cell cycle progression by separable, yet overlapping, pathways  Academic Article
• CD4 is expressed on murine pluripotent hematopoietic stem cells  Academic Article
• Cd40 ligand-mediated interactions are involved in the generation of memory cd8(+) cytotoxic t lymphocytes (ctl) but are not required for the maintenance of ctl memory following virus infection  Academic Article
• Cell migration and the anatomic control of thymocyte precursor differentiation  Academic Article
• Characterization in vitro and engraftment potential in vivo of human progenitor t cells generated from hematopoietic stem cells  Academic Article
• Characterization of vascular adhesion molecules that may facilitate progenitor homing in the post-natal mouse thymus  Academic Article
• Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice  Academic Article
• Clonal analysis of primary marrow stroma: functional homogeneity in support of lymphoid and myeloid cell lines and identification of positive and negative regulators  Academic Article
• Commitment and developmental potential of extrathymic and intrathymic T cell precursors: Plenty to choose from  Academic Article
• Commitment issues: linking positive selection signals and lineage diversification in the thymus  Academic Article
• Commitment to the T-cell receptor-alpha-beta or receptor-gamma-delta lineages can occur just prior to the onset of CD4 and CD8 expression among immature thymocytes  Academic Article
• Comparison of the activity of doxorubicin analogs using colony-forming assays and human xenografts  Academic Article
• Constitutive systemic expression of il-1ra or soluble tnf receptor by genetically modified hematopoietic cells suppresses lps induction of il-6 and il-10  Academic Article
• Contribution of receptor editing to the antibody repertoire  Academic Article
• Converting stem cells to dendritic cells by agonist antibodies from unbiased morphogenic selections  Academic Article
• Cooperation between both Wnt/β-catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion  Academic Article
• Critical role for CXCR4 signaling in progenitor localization and T cell differentiation in the postnatal thymus  Academic Article
• Cryoem structure at 9 Å resolution of an adenovirus vector targeted to hematopoietic cells  Academic Article
• Cytokines suppress apoptosis independent of increases in reactive oxygen levels  Academic Article
• DNA repair is crucial for maintaining hematopoietic stem cell function  Academic Article
• Demonstration of a hematopoietic stem-cell antigen (SC-1) on a murine lymphoma and isolation of variants lacking the antigen  Academic Article
• Development of ecdysone-regulated lentiviral vectors  Academic Article
• Direct comparison of Dll1-and Dll4-mediated notch activation levels shows differential lymphomyeloid lineage commitment outcomes  Academic Article
• Disruption of the arf-mdm2-p53 tumor suppressor pathway in myc-induced lymphomagenesis  Academic Article
• Donor variation in the growth properties and osteogenic potential of human marrow stromal cells  Academic Article
• Early commitment: T cell progenitors in the blood  Academic Article
• Early hematopoietic stem cells (pre-CFU) studied in long-term culture of murine bone marrow [Article in Russian]  Academic Article
• Effect of reishi polysaccharides on human stem/progenitor cells  Academic Article
• Effects of long-term cryopreservation on peripheral blood progenitor cells  Academic Article
• Embryonic-like stem cells from umbilical cord blood and potential for neural modeling  Academic Article
• Eupalinilide E inhibits erythropoiesis and promotes the expansion of hematopoietic progenitor cells  Academic Article
• Euphohelioscopin A is a PKC activator capable of inducing macrophage differentiation  Academic Article
• Exploring stem cell biology with small molecules  Academic Article
• Expression of c-Fes protein isoforms correlates with differentiation in myeloid leukemias  Academic Article
• Expression of tie receptor tyrosine kinase in leukemia-cell lines  Academic Article
• Fate of t-cells and b-cells transferred to scid mice  Academic Article
• Functional b cell receptor transgene allows efficient il-7-independent maturation of b cell precursors  Academic Article
• Gene expression profile of murine long-term reconstituting vs. Short-term reconstituting hematopoietic stem cells  Academic Article
• Genetic regulation of commitment to interleukin 4 production by a cd4(+) t cell-intrinsic mechanism  Academic Article
• Gp33-38, an early human T-cell activation antigen  Academic Article
• Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger  Academic Article
• Hematopoietic differentiation of embryonic stem cells  Academic Article
• Hematopoietic stem cell gene therapy for the multisystemic lysosomal storage disorder cystinosis  Academic Article
• Hematopoietic tissue factor-protease-activated receptor 2 signaling promotes hepatic inflammation and contributes to pathways of gluconeogenesis and steatosis in obese mice  Academic Article
• Human cord blood progenitors sustain thymic T-cell development and a novel form of angiogenesis  Academic Article
• Human dendritic cells genetically engineered to express high levels of the human epithelial tumor antigen mucin (MUC-1)  Academic Article
• IP3 3-kinase B controls hematopoietic stem cell homeostasis and prevents lethal hematopoietic failure in mice  Academic Article
• IP3 3-kinase B prevents bone marrow failure  Academic Article
• Identification of a brain theta-positive, secretory-cell from hematopoietic tissues  Academic Article
• Identification of primitive hematopoietic stem cells in mice by the limiting dilution method [Article in Russian]  Academic Article
• Immunoglobulin gene rearrangement in b-cell deficient mice generated by targeted deletion of the j(h) locus  Academic Article
• Impaired lymphopoiesis and altered b cell subpopulations in mice overexpressing lnk adaptor protein  Academic Article
• Improved outcome for high-risk acute myeloid leukemia patients using autologous bone marrow transplantation and monoclonal antibody-purged bone marrow  Academic Article
• In vitro drug testing using hemopoietic cells: goals and limitations  Academic Article
• Induction of hematopoietic microenvironment by the extracellular matrix from long-term bone marrow cultures  Academic Article
• Insertion and truncation of c-myb by murine leukemia-virus in a myeloid cell-line derived from cultures of normal hematopoietic-cells  Academic Article
• Insulin-like growth factor-binding protein 2 secreted by a tumorigenic cell line supports ex vivo expansion of mouse hematopoietic stem cells  Academic Article
• JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity  Academic Article
• Kinetics of steady-state differentiation and mapping of intrathymic-signaling environments by stem cell transplantation in nonirradiated mice  Academic Article
• Limited proliferative potential of primitive hematopoietic stem cells: hematopoiesis by clonal succession  Academic Article
• Lipopolysaccharide-binding protein as a major plasma protein responsible for endotoxemic shock  Academic Article
• Loss of t cell and b cell quiescence precedes the onset of microbial flora-dependent wasting disease and intestinal inflammation in gimap5-deficient mice  Academic Article
• Lymphocyte development from stem-cells  Academic Article
• Many roads, one destination for T cell progenitors  Academic Article
• Mapping precursor movement through the postnatal thymus reveals specific microenvironments supporting defined stages of early lymphoid development  Academic Article
• Mimicry of erythropoietin by a nonpeptide molecule  Academic Article
• Mouse hematopoietic stem-cells  Academic Article
• Mouse hematopoietic stem-cells and the interaction of c-kit receptor and steel factor  Academic Article
• Murine T cells with invariant gamma delta antigen receptors: origin, repertoire, and specificity  Academic Article
• Myeloid development is selectively disrupted in PU.1 null mice  Academic Article
• Myeloid-biased hematopoietic stem cells have extensive self-renewal capacity but generate diminished lymphoid progeny with impaired IL-7 responsiveness  Academic Article
• Mystery solved: VSV-G-LVs do not allow efficient gene transfer into unstimulated T cells, B cells, and HSCs because they lack the LDL receptor  Academic Article
• Na-seq: A discovery tool for the analysis of chromatin structure and dynamics during differentiation  Academic Article
• PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells  Academic Article
• PU.1 and the granulocyte- and macrophage colony-stimulating factor receptors play distinct roles in late-stage myeloid cell differentiation  Academic Article
• Paucity of V-D-D-J rearrangements and V-H replacement events in lupus prone and nonautoimmune TdT(-/-) and TdT(+/+) mice  Academic Article
• Pharmacological targeting of the thrombomodulin-activated protein c pathway mitigates radiation toxicity  Academic Article
• Phenotype, function, and in vivo migration and survival of allogeneic dendritic cell progenitors genetically engineered to express TGF-beta  Academic Article
• Precursor frequency, nonlinear proliferation, and functional maturation of virus-specific CD4(+) T cells  Academic Article
• Predominance of the prototypic-t15 antiphosphorylcholine junctional sequence in neonatal pre-b-cells  Academic Article
• Profound atrophy of the bone-marrow reflecting major histocompatibility complex class ii-restricted destruction of stem-cells by cd4+ cells  Academic Article
• Prolonged systemic expression of human IL-1 receptor antagonist (hIL-1ra) in mice reconstituted with hematopoietic-cells transduced with a retrovirus carrying the hIL-1ra cDNA  Academic Article
• Protein tyrosine phosphatase containing sh2 domains - characterization, preferential expression in hematopoietic-cells, and localization to human-chromosome 12p12-p13  Academic Article
• Protein-energy malnutrition halts hemopoietic progenitor cells in the G0/G1 cell cycle stage, thereby altering cell production rates  Academic Article
• RNA splicing modulation selectively impairs leukemia stem cell maintenance in secondary human AML  Academic Article
• Rapamycin relieves lentiviral vector transduction resistance in human and mouse hematopoietic stem cells  Academic Article
• Rapid expansion and IL-4 expression by Leishmania-specific naive helper T cells in vivo  Academic Article
• Receptor editing in a transgenic mouse model: Site, efficiency, and role in b cell tolerance and antibody diversification  Academic Article
• Recognition of human t-leukemia virus (htlv-1) envelope by human cd4(+) t-cell lines from htlv-1 seronegative individuals - specificity and clonal heterogeneity  Academic Article
• Reduced hematopoietic reserves in DNA interstrand crosslink repair-deficient ercc1(-/-) mice  Academic Article
• Regulation of t cell receptor gamma gene expression by cytokines in murine hematopoietic cells  Academic Article
• Retroviral gene transfer and sustained expression of human arylsulfatase A  Academic Article
• Role of homology-directed recombination - predominantly productive rearrangements of H81X in newborns but not in adults  Academic Article
• Role of the mammalian target of rapamycin pathway in lentiviral vector transduction of hematopoietic stem cells  Academic Article
• Role of thymic organ structure and stromal composition in steady-state postnatal T-cell production  Academic Article
• SOD2 deficiency in hematopoietic cells in mice results in reduced red blood cell deformability and increased heme degradation  Academic Article
• Safety and efficacy of a tCD25 preselective combination anti-HIV lentiviral vector in human hematopoietic stem and progenitor cells  Academic Article
• Shp2 is a target of the immunosuppressant tautomycetin  Academic Article
• Small-molecule regulators of human stem cell self-renewal  Academic Article
• Somatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesis  Academic Article
• Splenic hemopoiesis in idiopathic thrombocytopenic purpura  Academic Article
• Stromal cells in long-term cultures: keys to the elucidation of hematopoietic development?  Academic Article
• Stromal cells provide the matrix for migration of early lymphoid progenitors through the thymic cortex  Academic Article
• Switching-on survival and repair response programs in islet transplants by bone marrow-derived vasculogenic cells  Academic Article
• T-cell development - t-cell lineage commitment revisited  Academic Article
• Targeting and hematopoietic suppression of human CD34+ cells by measles virus  Academic Article
• The blood contains multiple distinct progenitor populations with clonogenic B and T lineage potential  Academic Article
• The cell surface glycoprotein CDCP1 in cancer: insights, opportunities, and challenges  Academic Article
• The clinical applications of genome editing in HIV  Academic Article
• The death-associated protein kinase 2 is up-regulated during normal myeloid differentiation and enhances neutrophil maturation in myeloid leukemic cells  Academic Article
• The polyamine oxidase inhibitor mdl-72,527 selectively induces apoptosis of transformed hematopoietic cells through lysosomotropic effects  Academic Article
• The proliferative potential of hematopoietic stem cells (CFUs) during serial passage in irradiated mice as foci of ectopic hematopoiesis [Article in Russian]  Academic Article
• The stromal cells' guide to the stem cell universe  Academic Article
• The t(8;21) fusion protein, aml1-eto, specifically represses the transcription of the p14(arf) tumor suppressor in acute myeloid leukemia  Academic Article
• Thymic skewing of the cd4/cd8 ratio maps with the t-cell receptor alpha-chain locus  Academic Article
• Thymus by numbers  Academic Article
• Tissue- and epitope-specific mechanisms account for the diverse effects of anti-CD44 antibodies on the maintenance of primitive hematopoietic progenitors in vitro  Academic Article
• Transcription factor PU.1 is necessary for development of thymic and myeloid progenitor-derived dendritic cells  Academic Article
• Transduction of a marker gene (Neor) into precursor cells of the hematopoietic microenvironment [Article in Russian]  Academic Article
• Transduction of human CD34+ cells that mediate long-term engraftment of NOD/SCID mice by HIV vectors  Academic Article
• Transformation and insertional mutagenesis in vitro of primary hematopoietic stem cell cultures  Academic Article
• Translational strategies and challenges in regenerative medicine  Academic Article
• Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis  Academic Article
• Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'  Academic Article
• Unusual germline DSP2 gene accounts for all apparent V-D-D-J rearrangements in newborn, but not adult, MRL mice  Academic Article
• Viral targeting of hematopoietic progenitors and inhibition of dc maturation as a dual strategy for immune subversion  Academic Article
• Wnt proteins are lipid-modified and can act as stem cell growth factors  Academic Article
• ZBTB1 is a determinant of lymphoid development  Academic Article
• Zoned out: Functional mapping of stromal signaling microenvironments in the thymus  Academic Article