subject area of
- A bifunctional molecule that displays context-dependent cellular activity Academic Article
- A novel in silico approach to drug discovery via computational intelligence Academic Article
- Anticancer properties of distinct antimalarial drug classes Academic Article
- Conformationally restricted analogues designed for selective inhibition of GAR Tfase versus thymidylate synthase or dihydrofolate reductase Academic Article
- In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen Academic Article
- In silico screening against wild-type and mutant Plasmodium falciparum dihydrofolate reductase Academic Article
- Linking high-throughput screens to identify MoAs and novel inhibitors of Mycobacterium tuberculosis dihydrofolate reductase Academic Article
- Modeling the inhibition of quadruple mutant Plasmodium falciparum dihydrofolate reductase by pyrimethamine derivatives Academic Article
- QSAR using evolved neural networks for the inhibition of mutant PfDHFR by pyrimethamine derivatives Academic Article
- Sequence-specific h-1, c-13 and n-15 assignment of the tmp-resistant dihydrofolate reductase mutant dhfr(f98y) in the ternary complex with tmp and nadph Academic Article
- Synthesis and biological evaluation of α- and γ-carboxamide derivatives of 10-CF3CO-DDACTHF Academic Article
- The molecular perspective: Methotrexate Academic Article