subject area of

• A bifunctional molecule that displays context-dependent cellular activity  Academic Article
• A novel in silico approach to drug discovery via computational intelligence  Academic Article
• Anticancer properties of distinct antimalarial drug classes  Academic Article
• Conformationally restricted analogues designed for selective inhibition of GAR Tfase versus thymidylate synthase or dihydrofolate reductase  Academic Article
• In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen  Academic Article
• In silico screening against wild-type and mutant Plasmodium falciparum dihydrofolate reductase  Academic Article
• Linking high-throughput screens to identify MoAs and novel inhibitors of Mycobacterium tuberculosis dihydrofolate reductase  Academic Article
• Modeling the inhibition of quadruple mutant Plasmodium falciparum dihydrofolate reductase by pyrimethamine derivatives  Academic Article
• QSAR using evolved neural networks for the inhibition of mutant PfDHFR by pyrimethamine derivatives  Academic Article
• Sequence-specific h-1, c-13 and n-15 assignment of the tmp-resistant dihydrofolate reductase mutant dhfr(f98y) in the ternary complex with tmp and nadph  Academic Article
• Synthesis and biological evaluation of α- and γ-carboxamide derivatives of 10-CF3CO-DDACTHF  Academic Article
• The molecular perspective: Methotrexate  Academic Article