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Conditioning, Operant

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  • 'Nicotine deprivation effect' in rats with intermittent 23-hour access to intravenous nicotine self-administration  Academic Article
  • (-)-2-oxa-4-aminobicylco[3.1.0]hexane-4,6-dicarboxylic acid (LY379268) and 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]piperidine (MTEP) similarly attenuate stress-induced reinstatement of cocaine seeking  Academic Article
  • 5-HT(6) receptor antagonism potentiates the behavioral and neurochemical effects of amphetamine but not cocaine  Academic Article
  • A dopamine partial agonist and antagonist block amphetamine self-administration in a progressive ratio schedule  Academic Article
  • Acquisition of and withdrawal from cocaine self-administration regulates 5-HT(1B) mRNA expression in rat striatum  Academic Article
  • Acquisition, expression, and reinstatement of ethanol-induced conditioned place preference in mice: Effects of opioid receptor-like 1 receptor agonists and naloxone  Academic Article
  • Alcohol withdrawal and conditioning  Academic Article
  • Alpha(1)-noradrenergic receptor antagonism blocks dependence-induced increases in responding for ethanol  Academic Article
  • Alpha(1)-noradrenergic system role in increased motivation for cocaine intake in rats with prolonged access  Academic Article
  • Altered Fos expression in neural pathways underlying cue-elicited drug seeking in the rat  Academic Article
  • An automated apparatus for the study of visual discriminations in pigeons  Academic Article
  • Animal models of craving for ethanol  Academic Article
  • Antagonism of heroin and morphine self-administration in rats by the morphine-6 beta-glucuronide antagonist 3-o-methylnaltrexone  Academic Article
  • Anxiolytic activity of steroid anesthetic alphaxalone  Academic Article
  • Attenuation of cue-induced heroin-seeking behavior by cannabinoid CB(1) antagonist infusions into the nucleus accumbens core and prefrontal cortex, but not basolateral amygdala  Academic Article
  • Behavioral and neurochemical responses to cocaine in periadolescent and adult rats  Academic Article
  • Bidirectional modulation of cocaine expectancy by phasic glutamate fluctuations in the nucleus accumbens  Academic Article
  • Binge-like acquisition of 3,4-methylenedioxypyrovalerone (MDPV) self-administration and wheel activity in rats  Academic Article
  • Blockade by naloxone of cocaine-induced hyperactivity, reverse tolerance and conditioned place preference in mice  Academic Article
  • Blockade of hypocretin receptor-1 preferentially prevents cocaine seeking: comparison with natural reward seeking  Academic Article
  • Blockade of nicotine self-administration with nicotinic antagonists in rats  Academic Article
  • Brain norepinephrine depleting lesions selectively enhance behavioral responsiveness to novelty  Academic Article
  • CaMKII activation in the entorhinal cortex disrupts previously encoded spatial memory  Academic Article
  • Cannabinoid modulation of opiate reinforcement through the ventral striatopallidal pathway  Academic Article
  • Cannabinoid receptor antagonist SR141716a decreases operant ethanol self administration in rats exposed to ethanol-vapor chambers  Academic Article
  • Cebranopadol blocks the escalation of cocaine intake and conditioned reinstatement of cocaine seeking in rats  Academic Article
  • Characterization of conditioned place preference to cocaine in congenic dopamine transporter knockout female mice  Academic Article
  • Chronic footshock, but not a physiological stressor, suppresses the alcohol deprivation effect in dependent rats  Academic Article
  • Chronic nicotine activates stress/reward-related brain regions and facilitates the transition to compulsive alcohol drinking  Academic Article
  • Cocaine but not food-seeking behavior is reinstated by stress after extinction  Academic Article
  • Cocaine self-administration is not dependent upon mesocortical α1 noradrenergic signaling  Academic Article
  • Control of cocaine-seeking behavior by drug-associated stimuli in rats: effects on recovery of extinguished operant-responding and extracellular dopamine levels in amygdala and nucleus accumbens  Academic Article
  • Corticosteroid-dependent plasticity mediates compulsive alcohol drinking in rats  Academic Article
  • Corticotropin-releasing factor (CRF) and alpha 2 adrenergic receptors mediate heroin withdrawal-potentiated startle in rats  Academic Article
  • Corticotropin-releasing factor 1 antagonists selectively reduce ethanol self-administration in ethanol-dependent rats  Academic Article
  • Corticotropin-releasing factor and schedule-induced-polydipsia  Academic Article
  • Dependence-induced increases in ethanol self-administration in mice are blocked by the crf, receptor antagonist antalarmin and by crf, receptor knockout  Academic Article
  • Depletion of dopamine in the caudate-nucleus but not in nucleus-accumbens impairs reaction-time performance in rats  Academic Article
  • Differences in the liability to self-administer intravenous cocaine between c57bl/6xsjl and balb/cbyj mice  Academic Article
  • Differential effects of dopamine receptor subtype blockade on performance of rats in a reaction-time paradigm  Academic Article
  • Differential effects of sigma(1) receptor blockade on self-administration and conditioned reinstatement motivated by cocaine vs natural reward  Academic Article
  • Differential expression of response-disruptive and somatic indices of opiate withdrawal during the initiation and development of opiate dependence  Academic Article
  • Differential-effects of ethanol on punished responding in the p-rats and np-rats  Academic Article
  • Disruption of cocaine self-administration following 6-hydroxydopamine lesions of the ventral tegmental area in rats  Academic Article
  • Distinct patterns of neural activation associated with ethanol seeking: Effects of naltrexone  Academic Article
  • Dopamine d2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats  Academic Article
  • Drosophila α/β mushroom body neurons form a branch-specific, long-term cellular memory trace after spaced olfactory conditioning  Academic Article
  • Drug specificity in extended access cocaine and heroin self-administration  Academic Article
  • Dynamic Nigrostriatal Dopamine Biases Action Selection  Academic Article
  • Effect of hypoxia on hypothalamic mechanisms  Academic Article
  • Effect of sigma(1) receptor antagonism on ethanol and natural reward seeking  Academic Article
  • Effects of amperozide, 8-OH-DPAT, and FG 5974 on operant responding for ethanol  Academic Article
  • Effects of beta-adrenoceptor antagonists on alcohol drinking by alcohol-dependent rats  Academic Article
  • Effects of coptis japonica on morphine-induced conditioned place preference in mice  Academic Article
  • Effects of corticotropin releasing-factor, desipramine and haloperidol on a drl schedule of reinforcement  Academic Article
  • Effects of d-amphetamine and apomorphine upon operant-behavior and schedule-induced licking in rats with 6-hydroxydopamine-induced lesions of the nucleus accumbens  Academic Article
  • Effects of dopamine agonists and antagonists on cocaine induced operant responding for a cocaine-associated stimulus  Academic Article
  • Effects of ginseng total saponin on cocaine-induced hyperactivity and conditioned place preference in mice  Academic Article
  • Effects of naltrexone, duloxetine, and a corticotropin-releasing factor type 1 receptor antagonist on binge-like alcohol drinking in rats  Academic Article
  • Effects of neuropeptide Y on appetitive and consummatory behaviors associated with alcohol drinking in Wistar rats with a history of ethanol exposure  Academic Article
  • Effects of oral ethanol self-administration on the eeg of alcohol-preferring and alcohol-nonpreferring rats  Academic Article
  • Effects of parametric feeding manipulations on behavioral performance in macaques  Academic Article
  • Effects of terguride, ropinirole, and acetyl-l-carnitine on methamphetamine withdrawal in the rat  Academic Article
  • Effects of the dopamine d-1 antagonist sch-23390 microinjected into the accumbens, amygdala or striatum on cocaine self-administration in the rat  Academic Article
  • Effects of the mGlu2/3 agonist LY379268 and the mGlu5 antagonist MTEP on ethanol seeking and reinforcement are differentially altered in rats with a history of ethanol dependence  Academic Article
  • Effects of the specific alpha 4 beta 2 nachr antagonist, 2-fluoro-3-(4-nitrophenyl) deschloroepibatidine, on nicotine reward-related behaviors in rats and mice  Academic Article
  • Enduring resistance to extinction of cocaine-seeking behavior induced by drug-related cues  Academic Article
  • Enhanced alcohol self-administration after intermittent versus continuous alcohol vapor exposure  Academic Article
  • Enhanced locomotor, reinforcing, and neurochemical effects of cocaine in serotonin 5-hydroxytryptamine 2C receptor mutant mice  Academic Article
  • Escalation of drug self-administration as a hallmark of persistent addiction liability  Academic Article
  • Escalation of methamphetamine self-administration in rats: A dose-effect function  Academic Article
  • Estrous cycle effects on operant responding for ethanol in female rats  Academic Article
  • Ethanol effects on delayed spatial matching as modeled by a negative exponential forgetting function  Academic Article
  • Extended access cocaine self-administration differentially activates dorsal raphe and amygdala corticotropin-releasing factor systems in rats  Academic Article
  • Extracellular fluctuations of dopamine and glutamate in the nucleus accumbens core and shell associated with lever-pressing during cocaine self-administration, extinction, and yoked cocaine administration  Academic Article
  • Free-choice responding for ethanol versus water in alcohol preferring (p) and unselected wistar rats is differentially modified by naloxone, bromocriptine, and methysergide  Academic Article
  • Functional interaction between opioid and cannabinoid receptors in drug self-administration  Academic Article
  • Gaba antagonist and benzodiazepine partial inverse agonist reduce motivated responding for ethanol  Academic Article
  • Gaba(a) receptor antagonism in the extended amygdala decreases ethanol self-administration in rats  Academic Article
  • Growth hormone secretagogue receptor (GHS-R1a) knockout mice exhibit improved spatial memory and deficits in contextual memory  Academic Article
  • Heroin and cocaine intravenous self-administration in rats - mediation by separate neural systems  Academic Article
  • Heroin-specific stimuli reinstate operant heroin-seeking behavior in rats after prolonged extinction  Academic Article
  • Increased ethanol self-administration after a period of imposed ethanol deprivation in rats trained in a limited access paradigm  Academic Article
  • Inhibition by mk-801 of cocaine-induced sensitization, conditioned place preference, and dopamine-receptor supersensitivity in mice  Academic Article
  • Inhibition by mk-801 of morphine-induced conditioned place preference and postsynaptic dopamine receptor supersensitivity in mice  Academic Article
  • Inhibition of 5-ht neurotransmission increases clonidine protective effects on naloxone-induced conditioned place aversion in morphine-dependent rats  Academic Article
  • Inhibition of kappa opioid receptors attenuated increased cocaine intake in rats with extended access to cocaine  Academic Article
  • Intra-amygdala muscimol decreases operant ethanol self-administration in dependent rats  Academic Article
  • Intravenous heroin and ethanol self administration by alcohol preferring aa and alcohol-avoiding ana rats  Academic Article
  • Intravenous self-administration of mephedrone, methylone and MDMA in female rats  Academic Article
  • Investigating Neural Correlates of Behavior in Freely Behaving Rodents Using Inertial Sensors  Academic Article
  • Involvement of the sigma(1) receptor in cocaine-induced conditioned place preference: Possible dependence on dopamine uptake blockade  Academic Article
  • Lack of self-administration of cocaine in dopamine d-1 receptor knock-out mice  Academic Article
  • Learning performance of normal and mutant Drosophila after repeated conditioning trials with discrete stimuli  Academic Article
  • Levels of neural progenitors in the hippocampus predict memory impairment and relapse to drug seeking as a function of excessive methamphetamine self-administration  Academic Article
  • Locus coeruleus lesions and learning in rat  Academic Article
  • Long latency event-related potentials in rats: Response of amygdala, nucleus accumbens, dorsal hippocampus and frontal cortex to changes in reward characteristics of conditioned stimuli  Academic Article
  • Long-term antagonism of κ opioid receptors prevents escalation of and increased motivation for heroin intake  Academic Article
  • MPZP: A novel small molecule corticotropin-releasing factor type 1 receptor (CRF1) antagonist  Academic Article
  • MT-7716, a potent NOP receptor agonist, preferentially reduces ethanol seeking and reinforcement in post-dependent rats  Academic Article
  • Mdma produces stimulant-like conditioned locomotor-activity  Academic Article
  • Measures of cocaine-seeking behavior using a multiple schedule of food and drug self-administration in rats  Academic Article
  • Mice lacking 5-ht7 receptors show specific impairments in contextual learning  Academic Article
  • Modeling relapse in animals  Academic Article
  • Molecular substrates for retrieval and reconsolidation of cocaine-associated contextual memory  Academic Article
  • Monoamine oxidase inhibition dramatically increases the motivation to self-administer nicotine in rats  Academic Article
  • Mu-opioid receptor knockout mice do not self-administer alcohol  Academic Article
  • N-[1-(2-benzo[b]thiophenyl)Cyclohexyl]- piperidine (BTCP) exerts cocaine-like actions on drug-maintained responding in rats  Academic Article
  • Neuropeptide s reinstates cocaine-seeking behavior and increases locomotor activity through corticotropin-releasing factor receptor 1 in mice  Academic Article
  • Neuropeptide y opposes alcohol effects on gamma-aminobutyric acid release in amygdala and blocks the transition to alcohol dependence  Academic Article
  • Nicotine vapor inhalation escalates nicotine self-administration  Academic Article
  • Novel cocaine vaccine linked to a disrupted adenovirus gene transfer vector blocks cocaine psychostimulant and reinforcing effects  Academic Article
  • Nuclear calcium/calmodulin regulates memory consolidation  Academic Article
  • Nucleus accumbens as a substrate for the aversive stimulus effects of opiate withdrawal  Academic Article
  • Nucleus-accumbens and amygdala are possible substrates for the aversive stimulus effects of opiate withdrawal  Academic Article
  • Operant alcohol self-administration in dependent rats: focus on the vapor model  Academic Article
  • Operant behavior and alcohol levels in blood and brain of alcohol-dependent rats  Academic Article
  • Opiate withdrawal signs precipitated by naloxone following a single exposure to morphine: Potentiation with a second morphine exposure  Academic Article
  • Orexin receptor antagonism prevents transcriptional and behavioral plasticity resulting from stimulant exposure  Academic Article
  • Patterns of responding differentiate intravenous nicotine self-administration from responding for a visual stimulus in C57BL/6J mice  Academic Article
  • Permanent impairment of birth and survival of cortical and hippocampal proliferating cells following excessive drinking during alcohol dependence  Academic Article
  • Pharmacological evidence for a motivational role of kappa-opioid systems in ethanol dependence  Academic Article
  • Phosphodiesterase 10A regulates alcohol and saccharin self-administration in rats  Academic Article
  • Preclinical validation of a novel cocaine exposure therapy for relapse prevention  Academic Article
  • Preferential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on conditioned reinstatement versus primary reinforcement: comparison between cocaine and a potent conventional reinforcer  Academic Article
  • Previous exposure to psychostimulants enhances the reinstatement of cocaine seeking by nucleus Accumbens AMPA  Academic Article
  • Priming with BTCP, a dopamine reuptake blocker, reinstates cocaine-seeking and enhances cocaine cue-induced reinstatement  Academic Article
  • RU 24969, a 5-HT1A/1B agonist, elevates brain stimulation reward thresholds: an effect reversed by GR 127935, a 5-HT1B/1D antagonist  Academic Article
  • Rapid induction of conditioned opiate withdrawal in the rat  Academic Article
  • Relative sensitivity to naloxone of multiple indexes of opiate withdrawal - a quantitative dose-response analysis  Academic Article
  • Restrained rats learn amphetamine-conditioned locomotion, but not place preference  Academic Article
  • Reversal of ethanol-seeking behavior by d1 and d2 antagonists in an animal model of relapse: Differences in antagonist potency in previously ethanol-dependent versus nondependent rats  Academic Article
  • Robust escalation of nicotine intake with extended access to nicotine self-administration and intermittent periods of abstinence  Academic Article
  • Satiating effects of cocaine are controlled by dopamine actions in the nucleus accumbens core  Academic Article
  • Selective orexin 2 receptor antagonism blocks cue-induced reinstatement, but not nicotine self-administration or nicotine-induced reinstatement  Academic Article
  • Selective reduction of alcohol drinking in sardinian alcohol-preferring rats by a sigma-1 receptor antagonist  Academic Article
  • Serotonin(1B) receptor stimulation enhances dopamine mediated reinforcement  Academic Article
  • Stimuli associated with a single cocaine experience elicit longlasting cocaine-seeking  Academic Article
  • Stimuli linked to ethanol availability activate hypothalamic CART and orexin neurons in a reinstatement model of relapse  Academic Article
  • Stress history increases alcohol intake in relapse: Relation to phosphodiesterase 10a  Academic Article
  • Subchronic cannabinoid agonist (WIN 55,212-2) treatment during cocaine abstinence alters subsequent cocaine seeking behavior  Academic Article
  • The actin cytoskeleton as a therapeutic target for the prevention of relapse to methamphetamine use  Academic Article
  • The alpha(1) adrenergic receptor antagonist prazosin reduces heroin self-administration in rats with extended access to heroin administration  Academic Article
  • The dopamine d-1 receptor antagonist sch 23390 injected into the dorsolateral bed nucleus of the stria terminalis decreased cocaine reinforcement in the rat  Academic Article
  • The dopamine-receptor agonist 7-oh-dpat modulates the acquisition and expression of morphine-induced place preference  Academic Article
  • The dorsal subiculum mediates the acquisition of conditioned reinstatement of cocaine-seeking  Academic Article
  • The effects of cocaine on operant responding for food in several strains of mice  Academic Article
  • The effects of fg-7142 and ro-15-1788 on the release of punished responding produced by chlordiazepoxide and ethanol in the rat  Academic Article
  • The effects of ro-15-4513 on the behavioral actions of ethanol in an operant reaction-time task and a conflict test  Academic Article
  • The gamma-aminobutyric acid-b receptor agonist baclofen attenuates responding for ethanol in ethanol-dependent rats  Academic Article
  • The influence of acute and chronic alcohol consumption on response time distribution in adolescent rhesus macaques  Academic Article
  • The long-term memory trace formed in the Drosophila α/β mushroom body neurons is abolished in long-term memory mutants  Academic Article
  • The mGluR5 antagonist MPEP suppresses the expression and reinstatement, but not the acquisition, of the ethanol-conditioned place preference in mice  Academic Article
  • The sigma-receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking  Academic Article
  • Tissue-specific expression of a type I adenylyl cyclase rescues the rutabaga mutant memory defect: In search of the engram  Academic Article
  • Traumatic stress reactivity promotes excessive alcohol drinking and alters the balance of prefrontal cortex-amygdala activity  Academic Article
  • Vasopressin potentiation in the performance of a learned appetitive task - reversal by a pressor antagonist analog of vasopressin  Academic Article
  • Δ9-tetrahydrocannabinol and endocannabinoid degradative enzyme inhibitors attenuate intracranial self-stimulation in mice  Academic Article
  • κ Opioid receptors in the nucleus accumbens shell mediate escalation of methamphetamine intake  Academic Article

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