subject area of
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- A DNA vaccine targeting survivin combines apoptosis with suppression of angiogenesis in lung tumor eradication Academic Article
- A combined ligand- and structure-based virtual screening protocol identifies submicromolar PPAR gamma partial agonists Academic Article
- A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol Academic Article
- A functional proteomic strategy to discover inhibitors for uncharacterized hydrolases Academic Article
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- A human microprotein that interacts with the mRNA decapping complex Academic Article
- A novel cross-talk in diacylglycerol signaling the rac-gap beta 2-chimaerin is negatively regulated by protein kinase c delta-mediated phosphorylation Academic Article
- A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol with potential anti-obesity effects Academic Article
- A second fatty acid amide hydrolase with variable distribution among placental mammals Academic Article
- A single vertebrate DNA virus protein disarms invertebrate immunity to RNA virus infection Academic Article
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- A superfolding Spinach2 reveals the dynamic nature of trinucleotide repeat-containing RNA Academic Article
- A two-antibody pan-ebolavirus cocktail confers broad therapeutic protection in ferrets and nonhuman primates Academic Article
- Activity-based protein profiling in vivo using a copper(i)-catalyzed azide-alkyne 3+2 cycloaddition Academic Article
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- Adenovirus core protein pvii is translocated into the nucleus by multiple import receptor pathways Academic Article
- Amphotericin B increases influenza A virus infection by preventing IFITM3-mediated restriction Academic Article
- An inactivating point mutation demonstrates that interaction of cAMP response element binding protein (CREB) with the CREB binding protein is not sufficient for transcriptional activation Academic Article
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- Analysis of the hormone-dependent regulation of a JunD-estrogen receptor chimera Academic Article
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- Animal models for retrovirus-induced immunodeficiency disease Academic Article
- Antibody-sensitive and antibody-resistant cell-to-cell spread by vaccinia virus: role of the A33R protein in anti body-resistant spread Academic Article
- Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation Academic Article
- Antigen compartmentation and t helper cell tolerance induction Academic Article
- Antisense masking reveals contributions of mrna- rrna base pairing to translation of gtx and fgf2 mrnas Academic Article
- Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models Academic Article
- Arenavirus nucleoproteins prevent activation of nuclear factor kappa b Academic Article
- Arenavirus reverse genetics for vaccine development Academic Article
- Attenuated measles virus as a vaccine vector Academic Article
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- Benzouracil-coumarin-arene conjugates as inhibiting agents for chikungunya virus Academic Article
- Biochanin A, a naturally occurring inhibitor of fatty acid amide hydrolase Academic Article
- Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus: clearance of virus in vivo Academic Article
- Borna disease virus requires cholesterol in both cellular membrane and viral envelope for efficient cell entry Academic Article
- Cargo- and adaptor-specific mechanisms regulate clathrin-mediated endocytosis Academic Article
- Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1 Academic Article
- Cell entry of Borna disease virus follows a clathrin-mediated endocytosis pathway that requires Rab5 and microtubules Academic Article
- Cell-to-cell spread of Borna disease virus proceeds in the absence of the virus primary receptor and furin-mediated processing of the virus surface glycoprotein Academic Article
- Cells expressing the RING finger Z protein are resistant to arenavirus infection Academic Article
- Cellular uptake and fate of PEGylated gold nanoparticles is dependent on both cell-penetration peptides and particle size Academic Article
- Characterization of a type-common human recombinant monoclonal antibody to herpes simplex virus with high therapeutic potential Academic Article
- Characterization of the structure and function of a novel map kinase kinase (mkk6) Academic Article
- Cholesteryl ester hydrolase activity is abolished in HSL(-/-) macrophages but unchanged in macrophages lacking KIAA1363 Academic Article
- Class assignment of sequence-unrelated members of enzyme superfamilies by activity-based protein profiling Academic Article
- Clinical isolates of measles virus use cd46 as a cellular receptor? Academic Article
- Clinical significance of st3gal iv expression in human renal cell carcinoma Academic Article
- Co-opting the Fanconi anemia genomic stability pathway enables herpesvirus DNA synthesis and productive growth Academic Article
- Coactivators PGC-1 beta and SRC-1 interact functionally to promote the agonist activity of the selective estrogen receptor modulator tamoxifen Academic Article
- Combining metabolite-based pharmacophores with Bayesian machine learning models for mycobacterium tuberculosis drug discovery Academic Article
- Conserved receptor-binding domains of Lake Victoria marburgvirus and Zaire ebolavirus bind a common receptor Academic Article
- Construction, affinity maturation, and biological characterization of an anti-tumor-associated glycoprotein-72 humanized antibody Academic Article
- Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity Academic Article
- Cross-reactive Antibody Response between SARS-CoV-2 and SARS-CoV Infections
- Delivering quantum dot-peptide bioconjugates to the cellular cytosol: escaping from the endolysosomal system Academic Article
- Detection and typing of herpes simplex viruses by using recombinant immunoglobulin fragments produced in bacteria Academic Article
- Determinants of initiation codon selection during translation in mammalian cells Academic Article
- Development of live-attenuated arenavirus vaccines based on codon deoptimization Academic Article
- Different mechanisms of cell entry by human-pathogenic old world and new world arenaviruses Academic Article
- Differential activation of CREB by Ca(2+)/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity Academic Article
- Differential inhibition of type I interferon induction by arenavirus nucleoproteins Academic Article
- Directed selection of recombinant human monoclonal-antibodies to herpes-simplex virus glycoproteins from phage display libraries Academic Article
- Discovery of a biomarker and lead small molecules to target r(GGGGCC)-associated defects in c9FTD/ALS Academic Article
- Discovery of a potent, selective, and efficacious class of reversible alpha-ketoheterocycle inhibitors of fatty acid amide hydrolase effective as analgesics Academic Article
- Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus Academic Article
- Dynamics of the hypoxia-inducible factor-1-vascular endothelial growth factor promoter complex Academic Article
- Early doors (Edo) mutant mouse reveals the importance of period 2 (PER2) PAS domain structure for circadian pacemaking Academic Article
- Early virus-host interactions dictate the course of a persistent infection Academic Article
- Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling Academic Article
- Ebola virus can be effectively neutralized by antibody produced in natural human infection Academic Article
- Eukaryotic expression cloning with an antimetastatic monoclonal antibody identifies a tetraspanin (peta-3/cd151) as an effector of human tumor cell migration and metastasis Academic Article
- Evaluation of PD 404,182 as an anti-HIV and anti-herpes simplex virus microbicide Academic Article
- Evaluation of diverse peptidyl motifs for cellular delivery of semiconductor quantum dots Academic Article
- Evidence that the hypermutated m protein of a subacute sclerosing panencephalitis measles virus actively contributes to the chronic progressive cns disease Academic Article
- Exposure of plasmodium sporozoites to the intracellular concentration of potassium enhances infectivity and reduces cell passage activity Academic Article
- Expression and characterization of von Willebrand factor dimerization defects in different types of von Willebrand disease Academic Article
- FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles Academic Article
- Follistatin-like protein-1 is a novel proinflammatory molecule Academic Article
- Functional analysis of a group A streptococcal glycoside hydrolase Spy1600 from family 84 reveals it is a beta-N-acetylglucosaminidase and not a hyaluronidase Academic Article
- Functional characterization of the genomic promoter of Borna disease virus (BDV): Implications of 3 '-terminal sequence heterogeneity for BDV persistence Academic Article
- General molecular strategy for development of arenavirus live-attenuated vaccines Academic Article
- Generation and characterization of a recombinant vesicular stomatitis virus expressing the glycoprotein of Borna disease virus Academic Article
- Generation of recombinant lymphocytic choriomeningitis viruses with trisegmented genomes stably expressing two additional genes of interest Academic Article
- Genetic analysis of influenza virus NS1 gene: a temperature-sensitive mutant shows defective formation of virus particles Academic Article
- Genetic analysis of the SARS-coronavirus spike glycoprotein functional domains involved in cell-surface expression and cell-to-cell fusion Academic Article
- Glucocorticoid compounds modify smoothened localization and hedgehog pathway activity Academic Article
- Glycan masking of Plasmodium vivax Duffy Binding Protein for probing protein binding function and vaccine development Academic Article
- Golgicide A reveals essential roles for GBF1 in Golgi assembly and function Academic Article
- HSV neutralization by the microbicidal candidate C5A Academic Article
- IFITM3 polymorphism rs12252-C restricts influenza A viruses Academic Article
- Identification and characterization of a new intron in Borna disease virus Academic Article
- Identification and expression of neu4, a novel murine sialidase Academic Article
- Identification and mechanism of 10-carbon fatty acid as modulating ligand of peroxisome proliferator-activated receptors Academic Article
- Identification and mechanism of action of a novel small-molecule inhibitor of arenavirus multiplication Academic Article
- Identification of 3-hydroxy-2-(3-hydroxyphenyl)-4H-1-benzopyran-4-ones as isoform-selective PKC-zeta inhibitors and potential therapeutics for psychostimulant abuse Academic Article
- Identification of two short internal ribosome entry sites selected from libraries of random oligonucleotides Academic Article
- Il-18 translational inhibition restricts ifn-gamma expression in crescentic glomerulonephritis Academic Article
- Immobilization of the N-terminal helix stabilizes prefusion paramyxovirus fusion proteins Academic Article
- Inhibition of endoplasmic reticulum glucosidases is required for in vitro and in vivo dengue antiviral activity by the iminosugar UV-4 Academic Article
- Inhibition of microRNA-302 (miR-302) by bone morphogenetic protein 4 (BMP4) facilitates the BMP signaling pathway Academic Article
- Inhibition of multiplication of the prototypic arenavirus LCMV by valproic acid Academic Article
- Inhibition of non-ATG translational events in cells via covalent small molecules targeting RNA Academic Article
- Inhibition of the severe acute respiratory syndrome 3cl protease by peptidomimetic alpha,beta-unsaturated esters Academic Article
- Inhibition of the type I interferon response by the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus Academic Article
- Inhibition, escape, and attenuated growth of severe acute respiratory syndrome coronavirus treated with antisense morpholino oligomers Academic Article
- Insulin receptor signaling regulates synapse number, dendritic plasticity, and circuit function in vivo Academic Article
- Integral membrane proteins of the nuclear envelope are dispersed throughout the endoplasmic reticulum during mitosis Academic Article
- Interleukin-1-alpha stimulates kc synthesis in rat mesangial cells - glucocorticoids inhibit kc induction by il-1 Academic Article
- Intracellular antibody against Clostridium-perfringens entero-toxin fails to counteract toxin-induced damage Academic Article
- Involvement of the v1/v2 variable loop structure in the exposure of human-immunodeficiency-virus type-1 gp120 epitopes induced by receptor-binding Academic Article
- Isolation of Borna disease virus from human brain tissue Academic Article
- Laminin-alpha 4 and integrin-linked kinase mutations cause human cardiomyopathy via simultaneous defects in cardiomyocytes and endothelial cells Academic Article
- Local clustering of transferrin receptors promotes clathrin-coated pit initiation Academic Article
- Low-affinity cytotoxic t-lymphocytes require ifn-gamma to clear an acute viral infection Academic Article
- Lung Kruppel-like factor contains an autoinhibitory domain that regulates its transcriptional activation by binding WWP1, an E3 ubiquitin ligase Academic Article
- Male germ cells support long-term propagation of Zika virus Academic Article
- Mammalian adaptation of influenza A(H7N9) virus is limited by a narrow genetic bottleneck Academic Article
- Mapping a common interaction site used by plasmodium falciparum duffy binding-like domains to bind diverse host receptors Academic Article
- Mapping enzyme active sites in complex proteomes Academic Article
- Measles virus recognizes its receptor, cd46, via two distinct binding domains within scr1-2 Academic Article
- Mechanisms for lymphocytic choriomeningitis virus glycoprotein cleavage, transport, and incorporation into virions Academic Article
- Mechanistic and structural requirements for active site labeling of phosphoglycerate mutase by spiroepoxides Academic Article
- Mice Lacking Functional STAT1 Are Highly Susceptible to Lethal Infection with Lassa Virus Academic Article
- Molecular basis of the interactions of the Nogo-66 receptor and its homolog NgR2 with myelin-associated glycoprotein: development of NgROMNI-Fc, a novel antagonist of CNS myelin inhibition Academic Article
- Molecular characterization and in vitro biological activity of placentin, a new member of the insulin gene family Academic Article
- Monoclonal-antibody analysis of purified and cell-associated tissue factor Academic Article
- Monocyte tissue factor-dependent activation of coagulation in hypercholesterolemic mice and monkeys is inhibited by simvastatin Academic Article
- Mouse RC/BTB2, a member of the RCC1 superfamily, localizes to spermatid acrosomal vesicles Academic Article
- Multifunctional compact zwitterionic ligands for preparing robust biocompatible semiconductor quantum dots and gold nanoparticles Academic Article
- Mutagenesis-mediated virus extinction: Virus-dependent effect of viral load on sensitivity to lethal defection Academic Article
- Mutations in the env gene of human immunodeficiency virus type 1 NDK isolates and the use of African green monkey CXCR4 as a co-receptor in COS-7 cells Academic Article
- N-linked glycosylation of Kv1.2 voltage-gated potassium channel facilitates cell surface expression and enhances the stability of internalized channels Academic Article
- Novel isoforms of the TFIID subunit TAF4 modulate nuclear receptor-mediated transcriptional activity Academic Article
- O-GlcNAcase uses substrate-assisted catalysis: kinetic analysis and development of highly selective mechanism-inspired inhibitors Academic Article
- Old world arenavirus infection interferes with the expression of functional alpha-dystroglycan in the host cell Academic Article
- Optimization of the central heterocycle of alpha-ketoheterocycle inhibitors of fatty acid amide hydrolase Academic Article
- Oxadiazoles have butyrate-specific conditional activity against mycobacterium tuberculosis Academic Article
- Palmitoylation of the cysteine-rich endodomain of the SARS-coronavirus spike glycoprotein is important for spike-mediated cell fusion Academic Article
- Partial agonists activate PPAR gamma using a helix 12 independent mechanism Academic Article
- Peptidomics of prolyl endopeptidase in the central nervous system Academic Article
- Plazomicin is effective in a non-human primate pneumonic plague model Academic Article
- Potent and selective alpha-ketoheterocycle-based inhibitors of the anandamide and oleamide catabolizing enzyme, fatty acid amide hydrolase Academic Article
- Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine Academic Article
- Protection against dengue disease by synthetic nucleic acid antibody prophylaxis/immunotherapy Academic Article
- Protection of nude mice by passive immunization with a type-common human recombinant monoclonal antibody against hsv Academic Article
- Proteomics analysis unravels the functional repertoire of coronavirus nonstructural protein 3 Academic Article
- Protocadherin-19 is essential for early steps in brain morphogenesis Academic Article
- Quantum-dot/dopamine bioconjugates function as redox coupled assemblies for in vitro and intracellular pH sensing Academic Article
- RIG-I enhanced interferon independent apoptosis upon Junin virus infection Academic Article
- Rapid and selective detection of fatty acylated proteins using omega-alkynyl-fatty acids and click chemistry Academic Article
- Recombinant human fab to glycoprotein-d neutralizes infectivity and prevents cell-to-cell transmission of herpes-simplex virus-1 and virus-2 in-vitro Academic Article
- Recombinant human monoclonal antibodies to ebola virus Academic Article
- Recombinant lymphocytic choriomeningitis virus expressing vesicular stomatitis virus glycoprotein Academic Article
- Recombinant measles viruses expressing heterologous antigens of mumps and simian immunodeficiency viruses Academic Article
- Redox-based probes as tools to monitor oxidized protein tyrosine phosphatases in living cells Academic Article
- Reduced cellular expression and activity of the P129T mutant of human fatty acid amide hydrolase: Evidence for a link between defects in the endocannabinoid system and problem drug use Academic Article
- Regulation of the transcriptional coactivator PGC-1 via MAPK-sensitive interaction with a repressor Academic Article
- Rescue from cloned cDNAs and in vivo characterization of recombinant pathogenic Romero and live-attenuated Candid #1 strains of Junin virus, the causative agent of Argentine hemorrhagic fever disease Academic Article
- Rescue of SARS-CoV-2 from a Single Bacterial Artificial Chromosome Academic Article
- Rho-family gtpases regulate p38 mitogen-activated protein-kinase through the downstream mediator pak1 Academic Article
- SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells Academic Article
- SCFCdc4 acts antagonistically to the PGC-1 alpha transcriptional coactivator by targeting it for ubiquitin-mediated proteolysis Academic Article
- Self-assembled quantum dot-peptide bioconjugates for selective intracellular delivery Academic Article
- Serological assays for severe acute respiratory syndrome coronavirus 2 (BARS-CoV-2), March 2020 Academic Article
- Site-directed elisa identifies a highly antigenic region of the simian immunodeficiency virus transmembrane glycoprotein Academic Article
- Six-microns-under acts upstream of Draper in the glial phagocytosis of apoptotic neurons Academic Article
- Small molecules targeting severe acute respiratory syndrome human coronavirus Academic Article
- Small-molecule inhibitors of the c-Fes protein-tyrosine kinase Academic Article
- Sperm associated antigen 6 (SPAG6) regulates fibroblast cell growth, morphology, migration and ciliogenesis Academic Article
- Stereospecific formation of interstrand carbinolamine DNA cross-links by crotonaldehyde- and acetaldehyde-derived alpha-CH3-gamma-OH-1,N2-propano-2'-deoxyguanosine adducts in the 5'-CpG-3' sequence Academic Article
- Structural basis for ligand regulation of the fatty acid-binding protein 5, peroxisome proliferator-activated receptor beta/delta (FABP5-PPAR beta/delta) signaling pathway Academic Article
- Structure and function correlation in histone H2A peptide-mediated gene transfer Academic Article
- Structure-based design of a FAAH variant that discriminates between the N-acyl ethanolamine and taurine families of signaling lipids Academic Article
- Substrate specificity profiling and identification of a new class of inhibitor for the major protease of the SARS coronavirus Academic Article
- Synthesis and characterization of BODIPY-labeled colchicine Academic Article
- T-705 (favipiravir) inhibition of arenavirus replication in cell culture Academic Article
- Tab-1 modulates intracellular localization of p38 map kinase and downstream signaling Academic Article
- Tak1, but not tab1 or tab2, plays an essential role in multiple signaling pathways in vivo Academic Article
- Takusan: A large gene family that regulates synaptic activity Academic Article
- Targeting the r(CGG) repeats that cause FXTAS with modularly assembled small molecules and oligonucleotides Academic Article
- The N-terminal nuclear localization sequences of liver X receptors α and β bind to importin α and are essential for both nuclear import and transactivating functions Academic Article
- The Nogo-66 receptor homolog NgR2 is a sialic acid-dependent receptor selective for myelin-associated glycoprotein Academic Article
- The PI3K/Akt pathway contributes to arenavirus budding Academic Article
- The ebola virus glycoprotein mediates entry via a non-classical dynamin-dependent macropinocytic pathway Academic Article
- The f-bar domains from srgap1, srgap2 and srgap3 regulate membrane deformation differently Academic Article
- The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors Academic Article
- The small RING finger protein Z drives arenavirus budding: Implications for antiviral strategies Academic Article
- Trans-inactivation of receptor tyrosine kinases by novel angiotensin ii at2 receptor-interacting protein, atip Academic Article
- UVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREs Academic Article
- Ultra-potent antibodies against respiratory syncytial virus: effects of binding kinetics and binding valence on viral neutralization Academic Article
- Ultrastructure of SARS-CoV, FIPV, and MHV revealed by electron cryomicroscopy Academic Article
- Unique small molecule entry inhibitors of hemorrhagic fever arenaviruses Academic Article
- Use of a nonviral vector to express a chimeric trna-ribozyme against lymphocytic choriomeningitis virus: Cytoplasmic accumulation of a catalytically competent transcript but minimal antiviral effect Academic Article
- Use of single-cycle infectious lymphocytic choriomeningitis virus to study hemorrhagic fever arenaviruses Academic Article
- V and c proteins of measles virus function as virulence factors in vivo Academic Article
- VLDL hydrolysis by hepatic lipase regulates PPARδ transcriptional responses Academic Article
- Viral E3 ubiquitin ligase-mediated degradation of a cellular E3: viral mimicry of a cellular phosphorylation mark targets the RNF8 FHA domain Academic Article
- Virus-induced diabetes in a transgenic model: Role of cross-reacting viruses and quantitation of effector t cells needed to cause disease Academic Article
- [Ca2+]i elevation and oxidative stress induce KCNQ1 protein translocation from the cytosol to the cell surface and increase slow delayed rectifier (IKs) in cardiac myocytes Academic Article
- cDNA cloning, structural features, and eucaryotic expression of human TAG-1/axonin-1 Academic Article