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Cartilage, Articular

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  • A Useful Combination of Quantitative Ultrashort Echo Time MR Imaging and a Probing Device for Biomechanical Evaluation of Articular Cartilage  Academic Article
  • A stem cell-based approach to cartilage repair  Academic Article
  • Adenoviral mediated delivery of FAS ligand to arthritic joints causes extensive apoptosis in the synovial lining  Academic Article
  • Adenoviral transfer of the viral IL-10 gene periarticularly to mouse paws suppresses development of collagen-induced arthritis in both injected and uninjected paws  Academic Article
  • Age- and site-associated biomechanical weakening of human articular cartilage of the femoral condyle  Academic Article
  • Aging-related differences in chondrocyte viscoelastic properties  Academic Article
  • Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis  Academic Article
  • An overview of underlying causes and animal models for the study of age-related degenerative disorders of the spine and synovial joints  Academic Article
  • Apoptosis in rheumatic disease  Academic Article
  • Assessment of mechanical properties of articular cartilage with quantitative three-dimensional ultrashort echo time (UTE) cones magnetic resonance imaging  Academic Article
  • Autophagy activation and protection from mitochondrial dysfunction in human chondrocytes  Academic Article
  • Autophagy activation by rapamycin reduces severity of experimental osteoarthritis  Academic Article
  • Autophagy and cartilage homeostasis mechanisms in joint health, aging and OA  Academic Article
  • Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis  Academic Article
  • Basic science of intra-articular fractures and posttraumatic osteoarthritis  Academic Article
  • Biomechanical regulation of matrix metalloproteinase-9 in cultured chondrocytes  Academic Article
  • Biomechanical, structural, and biochemical indices of degenerative and osteoarthritic deterioration of adult human articular cartilage of the femoral condyle  Academic Article
  • Biomechanics of cartilage articulation  Academic Article
  • Both microRNA-455-5p and-3p repress hypoxia-inducible factor-2 alpha expression and coordinately regulate cartilage homeostasis  Academic Article
  • C/EBP homologous protein drives pro-catabolic responses in chondrocytes  Academic Article
  • Cartilage and joint inflammation - regulation of IL-8 expression by human articular chondrocytes  Academic Article
  • Cartilage cell clusters  Academic Article
  • Caspase inhibitors reduce severity of cartilage lesions in experimental osteoarthritis  Academic Article
  • Cell death in cartilage  Academic Article
  • Cell density modulates apoptosis in human articular chondrocytes  Academic Article
  • Cellular and extracellular matrix changes in anterior cruciate ligaments during human knee aging and osteoarthritis  Academic Article
  • Characterization of selective exosite-binding inhibitors of matrix metalloproteinase 13 that prevent articular cartilage degradation in vitro  Academic Article
  • Chemotaxis of human articular chondrocytes and mesenchymal stem cells  Academic Article
  • Chondrocyte AMP-activated protein kinase activity suppresses matrix degradation responses to proinflammatory cytokines interleukin-1 beta and tumor necrosis factor alpha  Academic Article
  • Chondrocyte apoptosis and nitric oxide production during experimentally induced osteoarthritis  Academic Article
  • Chondrocyte apoptosis and regional differential expression of nitric oxide in the medial meniscus following partial meniscectomy  Academic Article
  • Chondrocyte calcium-sensing receptor expression is up-regulated in early guinea pig knee osteoarthritis and modulates PTHrP, MMP-13, and TIMP-3 expression  Academic Article
  • Chondrocyte clusters adjacent to sites of cartilage degeneration have characteristics of progenitor cells  Academic Article
  • Chondrocyte-derived apoptotic bodies and calcification of articular cartilage  Academic Article
  • Chromatin protein HMGB2 regulates articular cartilage surface maintenance via beta-catenin pathway  Academic Article
  • Comparative biomechanical analysis of human and caprine knee articular cartilage  Academic Article
  • Comparison of cartilage histopathology assessment systems on human knee joints at all stages of osteoarthritis development  Academic Article
  • Computational wear simulation of patellofemoral articular cartilage during in vitro testing  Academic Article
  • Constitutive intra-articular expression of human IL-1 beta following gene transfer to rabbit synovium produces all major pathologies of human rheumatoid arthritis  Academic Article
  • Correlation between MMP-13 and HDAC7 expression in human knee osteoarthritis  Academic Article
  • Correlation between anatomic features and low-field magnetic resonance imaging of the equine metacarpophalangeal joint  Academic Article
  • Cross-reactive epitope with klebsiella-pneumoniae nitrogenase in articular tissue of hla-b27+ patients with ankylosing-spondylitis  Academic Article
  • Cyclic GMP and cGMP-binding phosphodiesterase are required for interleukin-1-induced nitric oxide synthesis in human articular chondrocytes  Academic Article
  • Cytokine regulation of facilitated glucose transport in human articular chondrocytes  Academic Article
  • Development and regulation of osteophyte formation during experimental osteoarthritis  Academic Article
  • Development of comprehensive functional genomic screens to identify novel mediators of osteoarthritis  Academic Article
  • Development of gene-based therapies for cartilage repair  Academic Article
  • Differential expression of tgf-beta isoforms by human articular chondrocytes in response to growth-factors  Academic Article
  • Differential mechanisms of inorganic pyrophosphate production by plasma cell membrane glycoprotein-1 and B10 in chondrocytes  Academic Article
  • Differential metabolic effects of glucosamine and N-acetylglucosamine in human articular chondrocytes  Academic Article
  • Differentiation-dependent and stimulus-specific expression of ILA, the human 4-1BB-homologue, in cells of mesenchymal origin  Academic Article
  • Differentiation-dependent effects of IL-1 and TGF-beta on human articular chondrocyte proliferation are related to inducible nitric-oxide synthase expression  Academic Article
  • Direct adenoviral gene transfer of viral IL-10 to rabbit knees with experimental arthritis ameliorates disease in both injected and contralateral control knees  Academic Article
  • Direct adenovirus-mediated IGF-l gene transduction of synovium induces persisting synovial fluid IGF-l ligand elevations  Academic Article
  • Direct adenovirus-mediated gene transfer of interleukin 1 and tumor necrosis factor alpha soluble receptors to rabbit knees with experimental arthritis has local and distal anti-arthritic effects  Academic Article
  • Direct adenovirus-mediated insulin-like growth factor i gene transfer enhances transplant chondrocyte function  Academic Article
  • Direct human cartilage repair using three-dimensional bioprinting technology  Academic Article
  • Distinct pathways regulate facilitated glucose transport in human articular chondrocytes during anabolic and catabolic responses  Academic Article
  • Dysregulated FOXO transcription factors in articular cartilage in aging and osteoarthritis  Academic Article
  • Effect of osteochondral graft insertion forces on chondrocyte viability  Academic Article
  • Effects of aging on articular cartilage homeostasis  Academic Article
  • Effects of perfusion and dynamic loading on human neocartilage formation in alginate hydrogels  Academic Article
  • Ex vivo gene transfer to chondrocytes in full-thickness articular cartilage defects: A feasibility study  Academic Article
  • Exosomes from IL-1β stimulated synovial fibroblasts induce osteoarthritic changes in articular chondrocytes  Academic Article
  • Expression and localization of connective tissue growth factor (CTGF/Hcs24/CCN2) in osteoarthritic cartilage  Academic Article
  • Expression of microRNA-146a in osteoarthritis cartilage  Academic Article
  • Expression of novel extracellular sulfatases Sulf-1 and Sulf-2 in normal and osteoarthritic articular cartilage  Academic Article
  • Expression of prepro-enkephalin in human articular chondrocytes is linked to cell-proliferation  Academic Article
  • Expression patterns and function of chromatin protein HMGB2 during mesenchymal stem cell differentiation  Academic Article
  • Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways  Academic Article
  • Fibroblast activation protein alpha is expressed by chondrocytes following a pro-inflammatory stimulus and is elevated in osteoarthritis  Academic Article
  • Fibroblast growth factor 4 directs gap junction expression in the mesenchyme of the vertebrate limb Bud  Academic Article
  • FoxO transcription factors support oxidative stress resistance in human chondrocytes  Academic Article
  • Gene therapy of arthritis  Academic Article
  • Gene transfer of p53 to arthritic joints stimulates synovial apoptosis and inhibits inflammation  Academic Article
  • Genetic enhancement of matrix synthesis by articular chondrocytes - comparison of different growth factor genes in the presence and absence of interleukin-1  Academic Article
  • Glucosamine activates autophagy in vitro and in vivo  Academic Article
  • Growth and differentiation of prechondrogenic cells on bioactive self-assembled peptide nanofibers  Academic Article
  • Growth-factor responsiveness of human articular chondrocytes - distinct profiles in primary chondrocytes, subcultured chondrocytes, and fibroblasts  Academic Article
  • Growth-factor responsiveness of human articular chondrocytes in aging and development  Academic Article
  • HIV-1 transactivator protein Tat induces proliferation and TGF-beta expression in human articular chondrocytes  Academic Article
  • Halofuginone attenuates osteoarthritis by inhibition of TGF-β activity and H-type vessel formation in subchondral bone  Academic Article
  • Hexosaminidase inhibitors as new drug candidates for the therapy of osteoarthritis  Academic Article
  • Histopathological changes in the human posterior cruciate ligament during aging and osteoarthritis: Correlations with anterior cruciate ligament and cartilage changes  Academic Article
  • Human IL-1ra gene transfer into human synovial fibroblasts is chondroprotective  Academic Article
  • Human articular chondrocytes exhibit sexual dimorphism in their responses to 17 beta-estradiol  Academic Article
  • Human chondrocyte apoptosis in response to mechanical injury  Academic Article
  • Human, viral or mutant human il-10 expressed after local adenovirus-mediated gene transfer are equally effective in ameliorating disease pathology in a rabbit knee model of antigen-induced arthritis  Academic Article
  • Hyaluronan concentration and size distribution in human knee synovial fluid: variations with age and cartilage degeneration  Academic Article
  • Hyaluronic acid and chondroitin sulfate content of osteoarthritic human knee cartilage: Site-specific correlation with weight-bearing force based on femorotibial angle measurement  Academic Article
  • IL-18 is produced by articular chondrocytes and induces proinflammatory and catabolic responses  Academic Article
  • IL-1ra/IGF-1 gene therapy modulates repair of microfractured chondral defects  Academic Article
  • IL-6 production by human articular chondrocytes - modulation of its synthesis by cytokines, growth-factors, and hormones in vitro  Academic Article
  • IL-8/CXCL8 and growth-related oncogene α/CXCL1 induce chondrocyte hypertrophic differentiation  Academic Article
  • Identification of mesenchymal progenitor cells in normal and osteoarthritic human articular cartilage  Academic Article
  • Il-1-beta and il-6 selectively induce transforming growth-factor-beta isoforms in human articular chondrocytes  Academic Article
  • Implantable sensor technology: from research to clinical practice  Academic Article
  • In situ tissue engineering using magnetically guided three-dimensional cell patterning  Academic Article
  • In vitro model of full-thickness cartilage defect healing  Academic Article
  • In vivo changes after mechanical injury  Academic Article
  • Increased intracellular ca2+ selectively suppresses il-1-induced no production by reducing inos messenger-rna stability  Academic Article
  • Increased matrix synthesis following adenoviral transfer of a transforming growth factor beta(1) gene into articular chondrocytes  Academic Article
  • Induction of cytokine expression by leukemia inhibitory factor  Academic Article
  • Inflammation-induced chondrocyte hypertrophy is driven by receptor for advanced glycation end products  Academic Article
  • Inflammatory events in cartilage in early stages of femoroacetabular impingement: Commentary on an article by Shingo Hashimoto, MD, PhD, et al.: "Molecular characterization of articular cartilage from young adults with femoroacetabular impingement"  Academic Article
  • Influence of cartilage extracellular matrix molecules on cell phenotype and neocartilage formation  Academic Article
  • Inhibition of cartilage destruction by double gene transfer of IL-1Ra and IL-10 involves the activin pathway  Academic Article
  • Inhibition of the development of collagen-induced arthritis in rhesus monkeys by a small molecular weight antagonist of CCR5  Academic Article
  • Inorganic pyrophosphate (PPI) in pathologic calcification of articular cartilage  Academic Article
  • Insulinlike growth factor-l gene therapy applications for cartilage repair  Academic Article
  • Integrin expression by human articular chondrocytes  Academic Article
  • Interleukin-1 induces pro-mineralizing activity of cartilage tissue transglutaminase and factor XIIIa  Academic Article
  • Interleukin-1-beta suppresses transforming growth factor-induced inorganic pyrophosphate (PPi) production and expression of the PPi-generating enzyme PC-1 in human chondrocytes  Academic Article
  • Interleukin-11, an inducible cytokine in human articular chondrocytes and synoviocytes, stimulates the production of the tissue inhibitor of metalloproteinases  Academic Article
  • Interleukin-17-induced gene expression in articular chondrocytes is associated with activation of mitogen-activated protein kinases and NF-kappa B  Academic Article
  • Interleukin-6 induces the synthesis of tissue inhibitor of metalloproteinases-1/erythroid potentiating activity (TIMP-1/EPA)  Academic Article
  • Intra-articular gene delivery and expression of interleukin-1Ra mediated by self-complementary adeno-associated virus  Academic Article
  • Linkage of chondrocyte apoptosis and cartilage degradation in human osteoarthritis  Academic Article
  • Linked decreases in liver kinase B1 and AMP-activated protein kinase activity modulate matrix catabolic responses to biomechanical injury in chondrocytes  Academic Article
  • Macro view of microrna function in osteoarthritis  Academic Article
  • Mechanical injury suppresses autophagy regulators and pharmacologic activation of autophagy results in chondroprotection  Academic Article
  • Mesenchymal progenitor cell markers in human articular cartilage: normal distribution and changes in osteoarthritis  Academic Article
  • Mesenchymal progenitor cells in adult human articular cartilage  Academic Article
  • MicroRNA-125b regulates the expression of aggrecanase-1 (ADAMTS-4) in human osteoarthritic chondrocytes  Academic Article
  • MicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responses  Academic Article
  • Mitochondrial biogenesis is impaired in osteoarthritis chondrocytes but reversible via peroxisome proliferator-activated receptor γ coactivator 1α.  Academic Article
  • Mitochondrial oxidative phosphorylation is a downstream regulator of nitric oxide effects on chondrocyte matrix synthesis and mineralization  Academic Article
  • Molecular network of cartilage homeostasis and osteoarthritis  Academic Article
  • Monocyte chemoattractant protein-1 (MCP-1) expression in human articular cartilage. Induction by peptide regulatory factors and differential effects of dexamethasone and retinoic acid  Academic Article
  • N-acetylglucosamine prevents IL-1 beta-mediated activation of human chondrocytes  Academic Article
  • One of two chondrocyte-expressed isoforms of cartilage intermediate-layer protein functions as an insulin-like growth factor 1 antagonist  Academic Article
  • Palmitate has proapoptotic and proinflammatory effects on articular cartilage and synergizes with interleukin-1  Academic Article
  • Pannocytes: Distinctive cells found in rheumatoid arthritis articular cartilage erosions  Academic Article
  • Parathyroid hormone-related protein is abundant in osteoarthritic cartilage, and the parathyroid hormone-related protein 1-173 isoform is selectively induced by transforming growth factor beta in articular chondrocytes and suppresses generation of extracellular inorganic pyrophosphate  Academic Article
  • Potential treatment of osteoarthritis by gene therapy  Academic Article
  • Production of the chemokine RANTES by articular chondrocytes and role in cartilage degradation  Academic Article
  • Profile of glycosaminoglycan-degrading glycosidases and glycoside sulfatases secreted by human articular chondrocytes in homeostasis and inflammation  Academic Article
  • Regulation of CD95 (Fas/APO-1)-induced apoptosis in human chondrocytes  Academic Article
  • Regulation of YKL-40 production by human articular chondrocytes  Academic Article
  • Regulation of cyclooxygenase-2 expression in normal human articular chondrocytes  Academic Article
  • Repair of cartilage defects in arthritic tissue with differentiated human embryonic stem cells  Academic Article
  • Structural and functional maturation of distal femoral cartilage and bone during postnatal development and growth in humans and mice  Academic Article
  • Subchondral bone of the human knee in aging and osteoarthritis  Academic Article
  • TSG-6 expression in human articular chondrocytes - possible implications in joint inflammation and cartilage degradation  Academic Article
  • The contralateral effect conferred by intra-articular adenovirus-mediated gene transfer of viral IL-10 is specific to the immunizing antigen  Academic Article
  • The effect of glycosaminoglycan loss on chondrocyte viability: a study on porcine cartilage explants  Academic Article
  • The osteoprotegerin/receptor activator of nuclear factor kappa B/receptor activator of nuclear factor kappa B ligand system in cartilage  Academic Article
  • The pathology of the end-stage osteoarthritic lesion of the knee: potential role in cartilage repair  Academic Article
  • The relationship of autophagy defects to cartilage damage during joint aging in a mouse model  Academic Article
  • The role of IFN regulatory factor-1 in synovitis and nitric oxide production  Academic Article
  • The role of nitric oxide in articular cartilage damage  Academic Article
  • The tetrabasic KKKK147-150 motif determines intracrine regulatory effects of PTHrP 1-173 on chondrocyte PPi metabolism and matrix synthesis  Academic Article
  • Tissue neogenesis and STRO-1 expression in immature and mature articular cartilage  Academic Article
  • Transglutaminase 2 is a marker of chondrocyte hypertrophy and osteoarthritis severity in the Hartley guinea pig model of knee OA  Academic Article
  • Transthyretin deposition in articular cartilage: a novel mechanism in the pathogenesis of osteoarthritis  Academic Article
  • Tyrosine kinases are involved with the expression of inducible nitric-oxide synthase in human articular chondrocytes  Academic Article
  • Ultrashort echo time MR imaging of osteochondral junction of the knee at 3 T: identification of anatomic structures contributing to signal intensity  Academic Article
  • Ultrashort-echo time MR imaging of the patella with bicomponent analysis: correlation with histopathologic and polarized light microscopic findings  Academic Article
  • Up-regulated expression of the phosphodiesterase nucleotide pyrophosphatase family member PC-1 is a marker and pathogenic factor for knee meniscal cartilage matrix calcification  Academic Article
  • Upregulated ank expression in osteoarthritis can promote both chondrocyte MMP-13 expression and calcification via chondrocyte extracellular PPi excess  Academic Article
  • Use of an antibody against the matrix metalloproteinase-generated aggrecan neoepitope FVDIPEN-COOH to assess the effects of stromelysin in a rabbit model of cartilage degradation  Academic Article
  • Using gene therapy to protect and restore cartilage  Academic Article
  • Value of biomarkers in osteoarthritis: current status and perspectives  Academic Article
  • WISP3-dependent regulation aggrecan production of type II collagen and in chondrocytes  Academic Article
  • Zone-specific gene expression patterns in articular cartilage  Academic Article
  • microRNAs and cartilage  Academic Article

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