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Antimetabolites, Antineoplastic

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  • Biological and structural evaluation of 10R- and 10S-methylthio-DDACTHF reveals a new role for sulfur in inhibition of glycinamide ribonucleotide transformylase  Academic Article
  • Cks overexpression enhances chemotherapeutic efficacy by overriding DNA damage checkpoints  Academic Article
  • Differences among allelic variants of human glutathione transferase A2-2 in the activation of azathioprine  Academic Article
  • Elevated fetal haemoglobin is a predictor of better outcome inMDS/AML patients receiving 5-aza-2-deoxycytidine (Decitabine)  Academic Article
  • Importance of a hypervariable active-site residue in human Mu class glutathione transferases catalyzing the bioactivation of chemotherapeutic thiopurine prodrugs  Academic Article
  • Multidimensional epistasis and fitness landscapes in enzyme evolution  Academic Article
  • Synthesis and evaluation of potential N-pi and N-sigma metal chelation sites within the beta-hydroxy-L-histidine subunit of bleomycin A(2): Functional characterization of imidazole N-pi metal complexation  Academic Article
  • Targeting AKT with the proapoptotic peptide, TAT-CTMP: A novel strategy for the treatment of human pancreatic adenocarcinoma  Academic Article
  • The molecular perspective: Methotrexate  Academic Article
  • The molecular perspective: Methotrexate  Academic Article

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