subject area of

• A T cell receptor-specific blockade of positive selection  Academic Article
• A high-yield purification procedure for alpha-chain and beta-chain of hla-dr antigens  Academic Article
• A population response analysis approach to assign class II HLA-epitope restrictions  Academic Article
• A quantitative dot immunobinding assay for human HLA class II antigens using nitrocellulose membrane filters  Academic Article
• A recurrent idiotype on monoclonal anti-human ia antibodies  Academic Article
• A role for acidic residues in di-leucine motif-based targeting to the endocytic pathway  Academic Article
• A single peptide-major histocompatibility complex ligand triggers digital cytokine secretion in CD4(+) T cells  Academic Article
• A structural framework for deciphering the link between I-A(g7) and autoimmune diabetes  Academic Article
• A study of complexes of class II invariant chain peptide: major histocompatibility complex class II molecules using a new complex-specific monoclonal antibody  Academic Article
• A t-cell receptor-v-alpha region selectively expressed in cd4+ cells  Academic Article
• Activation of CD74 inhibits migration of human mesenchymal stem cells  Academic Article
• Adoptive immunotherapy induces cns dendritic cell recruitment and antigen presentation during clearance of a persistent viral infection  Academic Article
• Allo-reactivity of mesenchymal stem cells in rhesus macaques is dose and haplotype dependent and limits durable cell engraftment in vivo  Academic Article
• Allogeneic induction of the human t-cell-instructed monocyte procoagulant response is rapid and is elicited by hla-dr  Academic Article
• Alteration of intracerebral cytokine production in mice infected with herpes-simplex virus type-1 and type-2  Academic Article
• Altered antigen presentation in mice lacking H2-O  Academic Article
• An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a  Academic Article
• An overview of antigen presentation and its central role in the immune response  Academic Article
• Analysis of T lymphocytes after bone marrow transplantation using monoclonal antibodies  Academic Article
• Analysis of naturally processed peptides eluted from HLA DRB1*0402 and *0404  Academic Article
• Anatomy of cd1-lipid antigen complexes  Academic Article
• Anergy induction in encephalitogenic t-cells by brain microvessel endothelial-cells is inhibited by interleukin-1  Academic Article
• Anti-l3t4 monoclonal-antibody inhibits t-cell activation by anti-t-cell receptor antibody through a pathway not involving associative recognition  Academic Article
• Antigen compartmentation and t helper cell tolerance induction  Academic Article
• Antigen presentation and t cell development in h2-m-deficient mice  Academic Article
• Antigen-driven selection of tcr in vivo: Related tcr alpha-chains pair with diverse tcr beta-chains  Academic Article
• Antigen-processing and presentation  Academic Article
• Assembly and intracellular transport of MHC class I and class II molecules  Academic Article
• Assessing the function of human unc-93b in toll-like receptor signaling and major histocompatibility complex ii response  Academic Article
• Autoimmune diabetes can be induced in transgenic major histocompatibility complex class-ii-deficient mice  Academic Article
• Autologous regulation of naive t cell homeostasis within the t cell compartment  Academic Article
• B7 expression on thymic medullary epithelium correlates with epithelium-mediated deletion of v-beta-5(+) thymocytes  Academic Article
• B7-1/2, but not PD-L1/2 molecules, are required on IL-10-treated tolerogenic DC and DC-derived exosomes for in vivo function  Academic Article
• Bone marrow-derived cells fail to induce positive selection in thymus reaggregation cultures  Academic Article
• CD4+ T cells pass through an effector phase during the process of in vivo tolerance induction  Academic Article
• CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes  Academic Article
• Catecholamines stimulate mhc class-i, class-ii, and invariant chain gene-expression in brain endothelium through different mechanisms  Academic Article
• Catecholamines stimulate the ifn-gamma-induced class-ii mhc expression on bovine brain capillary endothelial-cells  Academic Article
• Characterization of human immunodeficiency virus type 1 (HIV-1) Gag- and Gag peptide-specific CD4(+) T-cell clones from an HIV-1-seronegative donor following in vitro immunization  Academic Article
• Characterization of the inflammatory response during acute measles encephalitis in nse-cd46 transgenic mice  Academic Article
• Chmp5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis  Academic Article
• Clonal selection of helper T cells is determined by an affinity threshold with no further skewing of TCR binding properties  Academic Article
• Control of mhc restriction by tcr v-alpha cdr1 and cdr2  Academic Article
• Coreceptor affinity for MHC defines peptide specificity requirements for TCR interaction with coagonist peptide-MHC  Academic Article
• Counteraction of HLA-C-mediated immune control of HIV-1 by Nef  Academic Article
• Critical role of IL-15-IL-15R for antigen-presenting cell functions in the innate immune response  Academic Article
• Crystal structure of MHC class II I-Ab in complex with a human CLIP peptide: prediction of an I-Ab peptide-binding motif  Academic Article
• Crystal structure of mouse cd1: An mhc-like fold with a large hydrophobic binding groove  Academic Article
• Crystal structures of two I-A(d)-peptide complexes reveal that high affinity can be achieved without large anchor residues  Academic Article
• Cutting edge: Trimolecular interaction of tcr with mhc class ii and bacterial superantigen shows a similar affinity to mhc : Peptide ligands  Academic Article
• Detailed in vivo analysis of interferon-gamma induced major histocompatibility complex expression in the central nervous system: Astrocytes fail to express major histocompatibility complex class i and ii molecules  Academic Article
• Detection of low-avidity CD4(+) T cells using recombinant artificial APC: following the antiovalbumin immune response  Academic Article
• Development and validation of a broad scheme for prediction of HLA class II restricted T cell epitopes  Academic Article
• Development of anti-CD74 antibody-drug conjugates to target glucocorticoids to immune cells  Academic Article
• Different Bla-g T cell antigens dominate responses in asthma versus rhinitis subjects  Academic Article
• Differential T cell responses to residual viral antigen prolong CD4(+) T cell contraction following the resolution of infection  Academic Article
• Differential regulation of antiviral T-cell immunity results in stable CD8(+) but declining CD4(+) T-cell memory  Academic Article
• Direct binding of secreted t-cell receptor beta chain to superantigen associated with class-ii major histocompatibility complex protein  Academic Article
• Distinct H-2-linked regulation of T-cell responses to the pre-S and S regions of the same hepatitis B surface antigen polypeptide allows circumvention of nonresponsiveness to the S region  Academic Article
• Distinct signal thresholds for the unique antigen receptor-linked gene expression programs in mature and immature b cells  Academic Article
• Do t cells need endogenous peptides for activation?  Academic Article
• Effective treatment of inflammatory disease models with exosomes derived from dendritic cells genetically modified to express il-4  Academic Article
• Encephalitogenic T-cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype  Academic Article
• Engineering protein for X-ray crystallography: the murine major histocompatibility complex class II molecule I-A(d)  Academic Article
• Engineering the polyproline II propensity of a class II major histocompatibility complex ligand peptide  Academic Article
• Enterotoxin residues determining t-cell receptor v-beta binding-specificity  Academic Article
• Exosomes derived from IL-10-treated dendritic cells can suppress inflammation and collagen-induced arthritis  Academic Article
• Expansion by self antigen is necessary for the induction of experimental autoimmune encephalomyelitis by T cells primed with a cross-reactive environmental antigen  Academic Article
• Expression of t-cell receptor genes in an antigen-specific hybridoma and radiation-induced variants  Academic Article
• Fiv infection of il-2-dependent and -independent feline lymphocyte lines: Host cells range distinctions and specific cytokine upregulation  Academic Article
• Genetic-regulation of the immune-response to hepatitis-b surface-antigen (hbsag) .5. T-cell proliferative response and cellular interactions  Academic Article
• Homeostasis of v(alpha)14i nkt cells  Academic Article
• How TCRs bind MHCs, peptides, and coreceptors  Academic Article
• Human cytomegalovirus in the pancreas of patients with type-2 diabetes - is there a relation to clinical-features, messenger-rna and protein expression of insulin, somatostatin, and mhc class-ii  Academic Article
• Immortalized clones of fibroblastic reticular cells activate virus-specific t cells during virus infection  Academic Article
• Immunization with recombinant hla classes i and ii, hiv-1 gp140, and siv p27 elicits protection against heterologous shiv infection in rhesus macaques  Academic Article
• Immunoincompetence in cancer-patients - assessment by in vitro stimulation tests and quantification of lymphocyte subpopulations  Academic Article
• In a transgenic model of spontaneous autoimmune diabetes, expression of a protective class II MHC molecule results in thymic deletion of diabetogenic CD8+ T cells  Academic Article
• In vivo MHC class II presentation of cytosolic proteins revealed by rapid automated tandem mass spectrometry and functional analyses  Academic Article
• Infection of bovine brain microvessel endothelial-cells with cowdria-ruminantium elicits il-1-beta, il-6, and il-8 messenger-rna production and expression of an unusual mhc class-ii dq-alpha transcript  Academic Article
• Inflammatory leukocytes and cytokines in the peptide-induced disease of experimental allergic encephalomyelitis in SJL and B10.PL mice  Academic Article
• Interference with major histocompatibility complex class-ii-restricted antigen presentation in the brain by herpes-simplex virus type-1 - a possible mechanism of evasion of the immune-response  Academic Article
• Interferon-gamma is required for lupus-like disease and lymphoaccumulation in mrl-lpr mice  Academic Article
• Interplay between superantigens and the immune-system  Academic Article
• Intracellular transport of class II MHC molecules directed by invariant chain  Academic Article
• Invariant chain distinguishes between the exogenous and endogenous antigen presentation pathways  Academic Article
• Invariant-cognate peptide exchange restores class II dimer stability in HLA-DM mutants  Academic Article
• Lcmv-specific, class-ii restricted cytotoxic t-cells in beta-2-microglobulin deficient mice  Academic Article
• Long-term MHC class II presentation of the EBV lytic protein BHRF1 by EBV latently infected B cells following capture of BHRF1 antigen  Academic Article
• Long-term xenogeneic chimeras - full differentiation of rat t-cells and b-cells in scid mice  Academic Article
• MHC class II+ exosomes in plasma suppress inflammation in an antigen-specific and Fas ligand/Fas-dependent manner  Academic Article
• MHC restriction: slip-sliding away  Academic Article
• Macrophage i-a/i-e expression and macrophage-stimulating lymphokines in murine lupus  Academic Article
• Major histocompatibility complex class II DOA sequences from three Antarctic seal species verify stabilizing selection on the DO locus  Academic Article
• Mapping and restriction of a dominant viral CD4(+) T cell core epitope by both MHC class I and MHC class II  Academic Article
• Mapping of the major histocompatibility complex and viral-antigens on the plasma-membrane of a measles virus-infected cell  Academic Article
• Mhc class ii engagement in brain endothelial cells induces protein kinase a-dependent il-6 secretion and phosphorylation of camp response element-binding protein  Academic Article
• Migratory response of mesenchymal stem cells to macrophage migration inhibitory factor and its antagonist as a function of colony-forming efficiency  Academic Article
• Monoclonal antibody-superantigen fusion proteins - tumor-specific agents for t-cell-based tumor-therapy  Academic Article
• Multiple pathways for antigen-independent activation of a T helper hybridoma  Academic Article
• Murine cytomegalovirus infection down-regulates mhc class ii expression on macrophages by induction of il-10  Academic Article
• N-terminal amino-acid-sequences of the alpha-chains and beta-chains of hla-dr1 and hla-dr2 antigens  Academic Article
• Natural IgE production in the absence of MHC class II cognate help  Academic Article
• Negative selection of T cells occurs throughout thymic development  Academic Article
• Neuropilin-1 expression on regulatory T cells enhances their interactions with dendritic cells during antigen recognition  Academic Article
• New design of MHC class II tetramers to accommodate fundamental principles of antigen presentation  Academic Article
• Nonpeptidic, noncovalent inhibitors of the cysteine protease cathepsin S  Academic Article
• Oral insulin treatment suppresses virus-induced antigen-specific destruction of beta cells and prevents autoimmune diabetes in transgenic mice  Academic Article
• Peripheral tolerance in transgenic mice: tolerance to class II MHC and non-MHC transgene antigens  Academic Article
• Pillars article: An alpha beta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex (Science, 1996, 274:209-219)  Academic Article
• Plasma-derived MHC class II+ exosomes from tumor-bearing mice suppress tumor antigen-specific immune responses  Academic Article
• Polymorphism within a tcrav family influences the repertoire through class i/ii restriction  Academic Article
• Post-translational addition of chondroitin sulfate glycosaminoglycans - role of n-linked oligosaccharide addition, trimming, and processing  Academic Article
• Preferential expression of tcr v alpha regions in cd4/cd8 subsets: Class discrimination or co-receptor recognition?  Academic Article
• Pregnancy as a natural model of allograft tolerance - interactions between adherent macrophages and trophoblast populations  Academic Article
• Profound atrophy of the bone-marrow reflecting major histocompatibility complex class ii-restricted destruction of stem-cells by cd4+ cells  Academic Article
• ROR1-targeted delivery of OSU-2S, a nonimmunosuppressive FTY720 derivative, exerts potent cytotoxicity in mantle-cell lymphoma in vitro and in vivo  Academic Article
• Rapid expansion and IL-4 expression by Leishmania-specific naive helper T cells in vivo  Academic Article
• Restoration of the lipopolysaccharide-responsive phenotype in C3H/HeJ peritoneal macrophage-P388D1 cell hybrids  Academic Article
• Role of chain pairing for the production of functional soluble IA major histocompatibility complex class II molecules  Academic Article
• Selection of aberrant class II restricted CD8(+) T cells in NOD mice expressing a glutamic acid decarboxylase (GAD) 65-specific T cell receptor transgene  Academic Article
• Selection of phage-displayed superantigen by binding to cell-surface mhc class ii  Academic Article
• Selective development of cd4+ t-cells in transgenic mice expressing a class-ii mhc-restricted antigen receptor  Academic Article
• Sequence of i-e genes from autoimmune new-zealand white mice  Academic Article
• Slc11a1 enhances the autoimmune diabetogenic T-cell response by altering processing and presentation of pancreatic islet antigens  Academic Article
• Structural polymorphism of the beta-chain of human hla-dr antigens  Academic Article
• Superantigen-staphylococcal-enterotoxin-a-dependent and antibody-targeted lysis of gd(2)-positive neuroblastoma-cells  Academic Article
• T cell contact with Ia antigens on nonhemopoietic cells in vivo can lead to immunity rather than tolerance  Academic Article
• T cell development in mice expressing CD1d directed by a classical MHC class II promoter  Academic Article
• T-Cell receptor V-region usage and antigen specificity. The cytochrome c model system  Academic Article
• T-cell activation by superantigens  Academic Article
• T-cell receptor beta-chain binding to enterotoxin superantigens  Academic Article
• The I-Ag7 MHC class II molecule linked to murine diabetes is a promiscuous peptide binder  Academic Article
• The TB-specific CD4(+) T cell immune repertoire in both cynomolgus and rhesus macaques largely overlap with humans  Academic Article
• The diabetogenic mouse MHC class II molecule I-A(g7) is endowed with a switch that modulates TCR affinity  Academic Article
• The function of follicular helper t cells is regulated by the strength of t cell antigen receptor binding  Academic Article
• The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain  Academic Article
• The lesions of cyclosporine-induced autoimmune disease can be equally well elicited by cd4 or cd8 effector t cells  Academic Article
• The peptide ligands mediating positive selection in the thymus control t cell survival and homeostatic proliferation in the periphery  Academic Article
• The role of h2-o and hla-do in major histocompatibility complex class ii-restricted antigen processing and presentation  Academic Article
• The unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via toll-like receptors 3, 7 and 9  Academic Article
• Thymic selection by a single mhc/peptide ligand: Autoreactive t cells are low-affinity cells  Academic Article
• Thymic selection defines multiple t-cell receptor v-beta repertoire phenotypes at the cd4/cd8 subset level  Academic Article
• Thymocyte expression of cathepsin L is essential for NKT cell development  Academic Article
• Thyroxine-binding antibodies inhibit T cell recognition of a pathogenic thyroglobulin epitope  Academic Article
• Tumor infarction in mice by antibody-directed targeting of tissue factor to tumor vasculature  Academic Article
• Ubiquitin-dependent control of class II MHC localization is dispensable for antigen presentation and antibody production  Academic Article
• Unrestricted recognition of a nonpeptide antigen by CD8+ cytolytic T lymphocytes  Academic Article
• Viral induction of central nervous system innate immune responses  Academic Article