subject area of

• PAS, present, and future: clues to the origins of circadian clocks  Academic Article
• "Don't know much bile-ology"  Academic Article
• "Resistance" to PSC-RANTES revisited: two mutations in human immunodeficiency virus type 1 HIV-1 SF162 or simian-human immunodeficiency virus SHIV SF162-p3 do not confer resistance  Academic Article
• "Viral deja vu" elicits organ-specific immune disease independent of reactivity to self  Academic Article
• 'Muscle-sparing' statins: preclinical profiles and future clinical use  Academic Article
• 'Nicotine deprivation effect' in rats with intermittent 23-hour access to intravenous nicotine self-administration  Academic Article
• 'SNO'-storms compromise protein activity and mitochondrial metabolism in neurodegenerative disorders  Academic Article
• 'Translocatory proteins' and 'protein transduction domains': A critical analysis of their biological effects and the underlying mechanisms  Academic Article
• 'Two-stage double-technique hybrid (TSDTH)' identification strategy for the analysis of BMP2-induced transdifferentiation of premyoblast C2C12 cells to osteoblast  Academic Article
• (-)-2-oxa-4-aminobicylco[3.1.0]hexane-4,6-dicarboxylic acid (LY379268) and 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]piperidine (MTEP) similarly attenuate stress-induced reinstatement of cocaine seeking  Academic Article
• (18)F Fluoroazabenzoxazoles as potential amyloid plaque PET tracers: synthesis and in vivo evaluation in rhesus monkey  Academic Article
• (18)F-labeled isoindol-1-one and isoindol-1,3-dione derivatives as potential PET imaging agents for detection of beta-amyloid fibrils  Academic Article
• (S)NO signals: Translocation, regulation, and a consensus motif  Academic Article
• -Amino acid substitution of peptide-mediated NF-κB suppression in mdx mice preserves therapeutic benefit in skeletal muscle, but causes kidney toxicity  Academic Article
• 1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) analogs of CC-1065 and the duocarmycins: synthesis and evaluation  Academic Article
• 1,3,8-Triazaspiro[4.5]decane-2,4-diones as efficacious pan-inhibitors of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) for the treatment of anemia  Academic Article
• 1-(2-(2,2,2-Trifluoroethoxy)ethyl-1H-pyrazolo 4,3-d pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors  Academic Article
• 1-(2-Ethoxyethyl)-1H-pyrazolo 4,3-d pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors  Academic Article
• 1-H NMR studies of a neurotoxin and a cardiotoxin from Naja mossambica mossambica: amide proton resonances  Academic Article
• 1-[2(R)-(2-amino-2-methylpropionylamino)-3-(1H-indol-3-yl)propionyl]- 3-benzylpiperidine-3(S)-carboxylic acid ethyl ester (L-163,540): a potent, orally bioavailable, and short-duration growth hormone secretagogue  Academic Article
• 1-beta-D-arabinofuranosylcytosine inhibits Borna disease virus replication and spread  Academic Article
• 1.35 and 2.07 a resolution structures of the red abalone sperm lysin monomer and dimer reveal features involved in receptor binding  Academic Article
• 11-deoxy prostaglandin F(2 alpha), a thromboxane A2 receptor agonist, partially alleviates embryo crowding in Lpar3(-/-) females  Academic Article
• 14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination  Academic Article
• 14-3-3 proteins in neuronal development and function  Academic Article
• 14-methoxymetopon, a highly potent mu opioid agonist, biphasically affects ethanol intake in Sardinian alcohol-preferring rats  Academic Article
• 15N metabolic labeling of mammalian tissue with slow protein turnover  Academic Article
• 15N-labeled brain enables quantification of proteome and phosphoproteome in cultured primary neurons  Academic Article
• 1B1075: a brain- and pituitary-specific mRNA that encodes a novel chromogranin/secretogranin-like component of intracellular vesicles  Academic Article
• 1G5: a calmodulin-binding, vesicle-associated, protein kinase-like protein enriched in forebrain neurites  Academic Article
• 2,5-diaminopyrimidines and 3,5-disubstituted azapurines as inhibitors of glycogen synthase kinase-3 (GSK-3)  Academic Article
• 2-(3,5-dimethylphenyl)tryptamine derivatives that bind to the GnRH receptor  Academic Article
• 2-(Pyrrolidin-1-yl)ethyl-3,4-dihydroisoquinolin-1(2H)-one Derivatives as Potent and Selective Histamine-3 Receptor Antagonists  Academic Article
• 2-Amino- 1,2,4 triazolo 1,5-a pyridines as JAK2 inhibitors  Academic Article
• 2-Amino-4-bis(aryloxybenzyl)aminobutanoic acids: A novel scaffold for inhibition of ASCT2-mediated glutamine transport  Academic Article
• 2-Aminobenzimidazoles as potent Aurora kinase inhibitors  Academic Article
• 2-Bromopalmitate analogues as activity-based probes to explore palmitoyl acyltransferases  Academic Article
• 2-Phenylbenzofuran derivatives alleviate mitochondrial damage via the inhibition of beta-amyloid aggregation  Academic Article
• 2-Propylthiouracil does not replace glutathione for the glutathione transferases  Academic Article
• 2-aminopyridines as highly selective inducible nitric oxide synthase inhibitors. Differential binding modes dependent on nitrogen substitution  Academic Article
• 2-chlorodeoxyadenosine in combination with cyclosporine inhibits the development of transplant arteriosclerosis in rat cardiac allografts  Academic Article
• 2-microglobulin: a free immunoglobulin domain  Academic Article
• 2G12-expressing B cell lines may aid in HIV carbohydrate vaccine design strategies  Academic Article
• 3,4,5-trisubstituted isoxazoles as novel PPAR delta agonists. Part 1  Academic Article
• 3,4,5-trisubstituted isoxazoles as novel PPAR delta agonists. Part 2  Academic Article
• 3-Aryl-5-phenoxymethyl-1,3-oxazolidin-2-ones as positive allosteric modulators of mGluR2 for the treatment of schizophrenia: Hit-to-lead efforts  Academic Article
• 3-OH-pip-BTCP, a metabolite of the potent DA uptake blocker BTCP, exerts cocaine-like action in rats  Academic Article
• 384 hanging drop arrays give excellent Z-factors and allow versatile formation of co-culture spheroids  Academic Article
• 3H-GABA uptake selectively labels identifiable neurons in the leech central nervous-system  Academic Article
• 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)pi perazine-1-carbothioamide (ML267), a Potent Inhibitor of Bacterial Phosphopantetheinyl Transferase That Attenuates Secondary Metabolism and Thwarts Bacterial Growth  Academic Article
• 4-Aminoindazolyl-dihydrofuro 3,4-d pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase  Academic Article
• 4-Aminopyridyl-based CYP51 inhibitors as anti-Trypanosoma cruzi drug leads with improved pharmacokinetic profile and in vivo potency  Academic Article
• 4-Hydroxyalk-2-enals are substrates for glutathione transferase  Academic Article
• 4-Methyl-6,7-dihydro-4H-triazolo 4,5-c pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidate  Academic Article
• 4-O-acetyl-N-acetylneuraminic acid in the N-linked carbohydrate structures of equine and guinea pig alpha 2-macroglobulins, potent inhibitors of influenza virus infection  Academic Article
• 5 alpha-Androstan-3 alpha,17 beta-diol is a hormone: stimulation of cAMP accumulation in human and dog prostate  Academic Article
• 5' cleavage site in eukaryotic pre-mRNA splicing is determined by the overall 5' splice region, not by the conserved 5' GU  Academic Article
• 5,​6-methanoleukotriene A(4): a potent specific inhibitor for 5-​lipoxygenase  Academic Article
• 5-HT(1A) receptor activation: short-term effects on the mRNA expression of the 5-HT(1A) receptor and galanin in the raphe nuclei  Academic Article
• 5-HT(1A) receptor binding in the dorsal raphe nucleus is implicated in the anxiolytic-like effects of Cinnamomum cassia  Academic Article
• 5-HT(1A) receptor mutant mice exhibit enhanced tonic, stress-induced and fluoxetine-induced serotonergic neurotransmission  Academic Article
• 5-HT(6) receptor antagonism potentiates the behavioral and neurochemical effects of amphetamine but not cocaine  Academic Article
• 5-HT(7) receptor inhibition and inactivation induce antidepressantlike behavior and sleep pattern  Academic Article
• 5-[(2-methyl-1,3-thiazol-4-yl)ethynyl]-2,3'-bipyridine: a highly potent, orally active metabotropic glutamate subtype 5 (mGlu5) receptor antagonist with anxiolytic activity  Academic Article
• 5-aminoimidazole-4-carboxyamide-ribonucleoside (AICAR)-stimulated hepatic expression of Cyp4a10, Cyp4a14, Cyp4a31, and other peroxisome proliferator-activated receptor alpha-responsive mouse genes is AICAR 5'-monophosphate-dependent and AMP-activated protein kinase-independent  Academic Article
• 5-lipoxygenase-activating protein inhibitors: development of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM103)  Academic Article
• 5S rRNA gene transcription factor IIIA alters the helical configuration of DNA  Academic Article
• 6-alkynyl fucose is a bioorthogonal analog for O-fucosylation of epidermal growth factor-like repeats and thrombospondin Type-1 repeats by protein O-fucosyltransferases 1 and 2  Academic Article
• 68Ga-PSMA-11 PET imaging of response to androgen receptor inhibition: first human experience  Academic Article
• 7-alkylidenecephalosporin esters as inhibitors of human leukocyte elastase  Academic Article
• 7-nitroindazole, nitric oxide synthase inhibitor, attenuates physical dependence on butorphanol in rat  Academic Article
• 8-Br-cyclic GMP mimics activation of muscarinic autoreceptor and inhibits acetylcholine release from rat hippocampal slices  Academic Article
• 8-Hydroxyquinoline and hydroxamic acid inhibitors of botulinum neurotoxin BoNT/A  Academic Article
• 8-OH-DPAT acts on both 5-HT1A and 5-HT7 receptors to induce hypothermia in rodents  Academic Article
• 8-Tetrahydropyran-2-yl chromans: highly selective beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors  Academic Article
• A 1,064 bp fragment from the promoter region of the Col11a2 gene drives LacZ expression not only in cartilage but also in osteoblasts adjacent to regions undergoing both endochondral and intramembranous ossification in mouse embryos  Academic Article
• A 28,000-Da GDP/GTP-binding protein specific to the nuclear envelope  Academic Article
• A 3-dimensional extracellular matrix as a delivery system for the transplantation of glioma-targeting neural stem/progenitor cells  Academic Article
• A 32 degree tail swing in brush border myosin I on ADP release  Academic Article
• A 46-nucleotide promoter segment from an IFN-alpha gene renders an unrelated promoter inducible by virus  Academic Article
• A 5' leader of Rbm3, a cold stress-induced mRNA, mediates internal initiation of translation with increased efficiency under conditions of mild hypothermia  Academic Article
• A 9-nt segment of a cellular mRNA can function as an internal ribosome entry site (IRES) and when present in linked multiple copies greatly enhances IRES activity  Academic Article
• A Bellagio consensus. Children's Vaccine Initiative Ad Hoc Committe on an investment strategy for measles control  Academic Article
• A CAT reporter construct allows ultrasensitive estimation of TNF synthesis, and suggests that the TNF gene has been silenced in non-macrophage cell lines  Academic Article
• A CCHC metal-binding domain in Nanos is essential for translational regulation  Academic Article
• A Clinical Indications Prediction Scale Based on TWIST1 for Human Mesenchymal Stem Cells  Academic Article
• A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response  Academic Article
• A CreER mouse to study melanin concentrating hormone signaling in the developing brain  Academic Article
• A DNA vaccine against vegf receptor 2 prevents effective angiogenesis and inhibits tumor growth  Academic Article
• A DNA vaccine targeting fos-related antigen 1 enhanced by il-18 induces long-lived t-cell memory against tumor recurrence  Academic Article
• A DNA vaccine targeting survivin combines apoptosis with suppression of angiogenesis in lung tumor eradication  Academic Article
• A DNA-based cancer vaccine enhances lymphocyte cross talk by engaging the nkg2d receptor  Academic Article
• A Drosophila nonvisual arrestin is required for the maintenance of olfactory sensitivity  Academic Article
• A FAAH-regulated class of N-acyl taurines that activates TRP ion channels  Academic Article
• A Gja8 (Cx50) point mutation causes an alteration of α3 connexin (Cx46) in semi-dominant cataracts of Lop10 mice  Academic Article
• A Golgi fragmentation pathway in neurodegeneration  Academic Article
• A High-Throughput Screen for Chemicals that Increase the Lifespan of Caenorhabditis elegans  Academic Article
• A Jekyll and Hyde profile: Type 1 interferon signaling plays a prominent role in the initiation and maintenance of a persistent virus infection  Academic Article
• A LC-MS-based workflow for measurement of branched fatty acid esters of hydroxy fatty acids  Academic Article
• A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells  Academic Article
• A New World primate deficient in tetherin-mediated restriction of human immunodeficiency virus type 1  Academic Article
• A P element with a novel fusion of reporters identifies regular, a C2H2 zinc-finger gene downstream of the circadian clock  Academic Article
• A PERIOD inhibitor buffer introduces a delay mechanism for CLK/CYC-activated transcription  Academic Article
• A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis  Academic Article
• A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate  Academic Article
• A Plasmodium gene family encoding Maurer's cleft membrane proteins: structural properties and expression profiling  Academic Article
• A Protective Strategy against Hyperinflammatory Responses Requiring the Nontranscriptional Actions of GPS2  Academic Article
• A Rab GTPase is required for homotypic assembly of the endoplasmic reticulum  Academic Article
• A Saccharomyces cerevisiae RNase H2 interaction network functions to suppress genome instability  Academic Article
• A T cell receptor-specific blockade of positive selection  Academic Article
• A THEMIS:SHP1 complex promotes T-cell survival  Academic Article
• A TRP channel that senses cold stimuli and menthol  Academic Article
• A Yersinia-enterocolitica serotype 0-3 lipopolysaccharide-specific monoclonal-antibody reacts more strongly with bacteria cultured at room-temperature than those cultured at 37-degrees-C  Academic Article
• A ZAP-70 kinase domain variant prevents thymocyte- positive selection despite signalling CD69 induction  Academic Article
• A bacterial and silkworm aminoacyl-tRNA synthetase have a common epitope which maps to the catalytic domain of each  Academic Article
• A base triple in the tetrahymena group i core affects the reaction equilibrium via a threshold effect  Academic Article
• A bifunctional molecule that displays context-dependent cellular activity  Academic Article
• A binding site for homeodomain and pax proteins is necessary for l1 cell adhesion molecule gene expression by pax-6 and bone morphogenetic proteins  Academic Article
• A binding site for pax proteins regulates expression of the gene for the neural cell adhesion molecule in the embryonic spinal cord  Academic Article
• A biometrical genome search in rats reveals the multigenic basis of blood-pressure variation  Academic Article
• A biparatopic HER2-targeting antibody-drug conjugate induces tumor regression in primary models refractory to or ineligible for HER2-targeted therapy  Academic Article
• A bisubstrate analog induces unexpected conformational changes in phosphoglycerate kinase from trypanosoma brucei  Academic Article
• A bivariate version of andrews plots  Academic Article
• A blueprint for HIV vaccine discovery  Academic Article
• A brain detoxifying enzyme for organophosphorus nerve poisons  Academic Article
• A brief period of hypoxia causes proteolysis of cytoskeletal proteins in hippocampal slices  Academic Article
• A broadly neutralizing human monoclonal antibody exhibits in vivo efficacy against both human metapneumovirus and respiratory syncytial virus  Academic Article
• A candidate circuit approach to investigating autism  Academic Article
• A catalytic antibody produces fluorescent tracers of gap junction communication in living cells  Academic Article
• A catalytically inactive mutant of the deubiquitylase YOD-1 enhances antigen cross-presentation  Academic Article
• A catechol-O-methyltransferase that is essential for auditory function in mice and humans  Academic Article
• A cdc6 protein-binding peptide selected using a bacterial two-hybrid-like system is a cell cycle inhibitor  Academic Article
• A cdk-independent function of mammalian cks1: Targeting of scfskp2 to the cdk inhibitor p27(kip1)  Academic Article
• A cdna clone for cytotactin contains sequences similar to epidermal growth factor-like repeats and segments of fibronectin and fibrinogen  Academic Article
• A cell free system to study reassembly of the nuclear-envelope at the end of mitosis  Academic Article
• A cell-autonomous requirement for the cell cycle regulatory protein, rb, in neuronal migration  Academic Article
• A cell-free biochemical complementation assay reveals complex and redundant cytosolic requirements for lrp endocytosis  Academic Article
• A cell-surface molecule involved in aggregation of embryonic liver-cells  Academic Article
• A cellular gene encodes scrapie prp 27-30 protein  Academic Article
• A cellular mechanism for dendritic spine loss in the pilocarpine model of status epilepticus  Academic Article
• A ceramide analogue inhibits T cell proliferative response through inhibition of glycosphingolipid synthesis and enhancement of N,N-dimethylsphingosine synthesis  Academic Article
• A ceramide-1-phosphate analogue, pcera-1, simultaneously suppresses tumour necrosis factor-alpha and induces interleukin-10 production in activated macrophages  Academic Article
• A change in the conformation of prions accompanies the emergence of a new prion strain  Academic Article
• A chemical approach for cell-specific targeting of nanomaterials: Small-molecule-initiated misfolding of nanoparticle corona proteins  Academic Article
• A chemical genomic analysis of decoquinate, a plasmodium falciparum cytochrome b inhibitor  Academic Article
• A chemical switch regulates fibrate specificity for peroxisome proliferator-activated receptor alpha (ppar alpha) versus liver x receptor  Academic Article
• A chemical, genetic, and structural analysis of the nuclear bile acid receptor fxr  Academic Article
• A chemically induced vaccine strategy for prostate cancer  Academic Article
• A chemically programmed antibody is a long-lasting and potent inhibitor of influenza neuraminidase  Academic Article
• A chemically stable fluorescent marker of the ureter  Academic Article
• A chimeric hiv-1 envelope glycoprotein trimer with an embedded granulocyte-macrophage colony-stimulating factor (gm-csf) domain induces enhanced antibody and t cell responses  Academic Article
• A chimeric mouse model of Gaucher disease  Academic Article
• A chloride channel reconstituted from fetal rat brain growth cones  Academic Article
• A chromatin binding-site in the tail domain of nuclear lamins that interacts with core histones  Academic Article
• A clonal analysis of tergite development in Drosophila of ultraabdominal and paradoxical genotypes  Academic Article
• A combination of buprenorphine and naltrexone blocks compulsive cocaine intake in rodents without producing dependence  Academic Article
• A combinatorial system for cloning and expressing the catalytic antibody repertoire in escherichia-coli  Academic Article
• A combined chemical and genetic approach for the generation of induced pluripotent stem cells  Academic Article
• A combined ligand- and structure-based virtual screening protocol identifies submicromolar PPAR gamma partial agonists  Academic Article
• A combined vascular catecholamine fluorescence method reveals the relative vascularity of rat locus coeruleus and the paraventricular and supraoptic nuclei of the hypothalamus  Academic Article
• A common and unstable copy number variant is associated with differences in glo1 expression and anxiety-like behavior  Academic Article
• A common antiviral cytotoxic lymphocyte-t epitope for diverse major histocompatibility complex haplotypes - implications for vaccination  Academic Article
• A common solution to group 2 influenza virus neutralization  Academic Article
• A comparative analysis of the immunological evolution of antibody 28B4  Academic Article
• A comparative encyclopedia of DNA elements in the mouse genome  Academic Article
• A comparative immunogenicity study of hiv-1 virus-like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble monomeric gp120  Academic Article
• A comparison between activated protein C and des-1-41-light chain-activated protein C in reactions with type 1 plasminogen activator inhibitor  Academic Article
• A comparison between microwave irradiation and decapitation: Basal levels of dynorphin and enkephalin and the effect of chronic morphine treatment on dynorphin peptides  Academic Article
• A comparison of 129S2/SvHsd and C57BL/6JO1aHsd mice on a test battery assessing sensorimotor, affective and cognitive behaviours: implications for the study of genetically modified mice  Academic Article
• A comparison of flexible and constrained haptens in eliciting antibody catalysts for paraoxon hydrolysis  Academic Article
• A comparison of intraperitoneal and subcutaneous temperature in freely moving rhesus macaques  Academic Article
• A comparison of match-only algorithms for the analysis of plasmodium falciparum oligonucleotide arrays  Academic Article
• A comparison of noninternalizing (herkinorin) and internalizing (DAMGO) mu-opioid agonists on cellular markers related to opioid tolerance and dependence  Academic Article
• A comparison of progesterone and R5020 binding in endometrium, ovary, pituitary, and hypothalamus  Academic Article
• A comparison of selected quantitative trait loci associated with alcohol use phenotypes in humans and mouse models  Academic Article
• A comparison of t cell memory against the same antigen induced by virus versus intracellular bacteria  Academic Article
• A comparison of the (Na + -K + )-ATPase activities found in isolated brush border and plasma membrane of the rat intestinal mucosa  Academic Article
• A comparison of the atomic model of F-actin with cryo-electron micrographs of actin and decorated actin  Academic Article
• A compass for stem-cell differentiation  Academic Article
• A complex containing the Sm protein CAR-1 and the RNA helicase CGH-1 is required for embryonic cytokinesis in Caenorhabditis elegans  Academic Article
• A complex ligase ribozyme evolved in vitro from a group I ribozyme domain  Academic Article
• A complex of Protocadherin-19 and N-cadherin mediates a novel mechanism of cell adhesion  Academic Article
• A complexin/synaptotagmin 1 switch controls fast synaptic vesicle exocytosis  Academic Article
• A complexity measure for selective matching of signals by the brain  Academic Article
• A comprehensive analysis of replicative lifespan in 4,698 Single-gene deletion strains uncovers conserved mechanisms of aging  Academic Article
• A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol  Academic Article
• A comprehensive survey of the Plasmodium life cycle by genomic, transcriptomic, and proteomic analyses  Academic Article
• A computational approach to correct arginine-to-proline conversion in quantitative proteomics  Academic Article
• A computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein induces apoptosis in infected cells  Academic Article
• A conformational transition at the n terminus of the prion protein features in formation of the scrapie isoform  Academic Article
• A conjugate vaccine using enantiopure hapten imparts superior nicotine-binding capacity  Academic Article
• A consensus-hemagglutinin-based DNA vaccine that protects mice against divergent H5N1 influenza viruses  Academic Article
• A conserved Val to Ile switch near the heme pocket of animal and bacterial nitric-oxide synthases helps determine their distinct catalytic profiles  Academic Article
• A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis  Academic Article
• A conserved family of prolyl-4-hydroxylases that modify HIF  Academic Article
• A conserved hiv gp120 glycoprotein structure involved in chemokine receptor binding  Academic Article
• A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase  Academic Article
• A conserved motif in the itk ph-domain is required for phosphoinositide binding and tcr signaling but dispensable for adaptor protein interactions  Academic Article
• A conserved proliferating cell nuclear antigen-interacting protein sequence in Chk1 is required for checkpoint function  Academic Article
• A conserved protein interaction interface on the type 5 G protein beta subunit controls proteolytic stability and activity of R7 family regulator of G protein signaling proteins  Academic Article
• A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension  Academic Article
• A conserved salt bridge in the G loop of multiple protein kinases is important for catalysis and for in vivo Lyn function  Academic Article
• A constitutive shade-avoidance mutant implicates TIR-NBS-LRR proteins in Arabidopsis photomorphogenic development  Academic Article
• A continuous assay for the spectrophotometric analysis of sulfotransferases using aryl sulfotransferase iv  Academic Article
• A cortical neuropeptide with neuronal depressant and sleep-modulating properties  Academic Article
• A cost-effective fluorescence mini-microscope for biomedical applications  Academic Article
• A credit-card library approach for disrupting protein-protein interactions  Academic Article
• A crf2 agonist administered into the central nucleus of the amygdala decreases ethanol self-administration in ethanol-dependent rats  Academic Article
• A critical analysis of codon optimization in human therapeutics  Academic Article
• A critical evaluation of a nicotine vaccine within a self-administration behavioral model  Academic Article
• A critical role for TORC1 in cellular senescence  Academic Article
• A critical role for the sphingosine analog aal-r in dampening the cytokine response during influenza virus infection  Academic Article
• A cross-species analysis in pancreatic neuroendocrine tumors reveals molecular subtypes with distinctive clinical, metastatic, developmental, and metabolic characteristics  Academic Article
• A cross-species analysis of a mouse model of breast cancer-specific osteolysis and human bone metastases using gene expression profiling  Academic Article
• A crucial role of mitochondrial Hsp40 in preventing dilated cardiomyopathy  Academic Article
• A crystal structure of a model of the repeating r(CGG) transcript found in fragile X syndrome  Academic Article
• A curcumin derivative that inhibits vinyl carbamate-induced lung carcinogenesis via activation of the Nrf2 protective response  Academic Article
• A curly-tail modifier locus, mct1, on mouse chromosome-17  Academic Article
• A customized self-assembling peptide hydrogel for dental pulp tissue engineering  Academic Article
• A cyclic nucleotide-dependent chloride conductance in olfactory receptor neurons  Academic Article
• A cyclic peptide-polymer probe for the detection of Clostridium botulinum neurotoxin serotype A  Academic Article
• A cyclin-dependent kinase inhibitor inducing cancer cell differentiation: biochemical identification using Xenopus egg extracts  Academic Article
• A cytolytic function for a sialic acid-binding lectin that is a member of the pentraxin family of proteins  Academic Article
• A decrease in the size of the basal ganglia following prenatal alcohol exposure - a preliminary-report  Academic Article
• A demonstration of the intrinsic importance of stabilizing hydrophobic binding and noncovalent van der Waals contacts dominant in the noncovalent CC-1065/b-DNA binding  Academic Article
• A derivative of the melanocortin receptor antagonist shu9119 (pg932) increases food intake when administered peripherally  Academic Article
• A designed peptidomimetic agonistic ligand of trka nerve growth factor receptors  Academic Article
• A designer AAV variant permits efficient retrograde access to projection neurons  Academic Article
• A detailed structural model of cytotactin - protein homologies, alternative rna splicing, and binding regions  Academic Article
• A detergent-activated tyrosinase from xenopus-laevis .1. Purification and partial characterization  Academic Article
• A developmental analysis of oligodendroglial integrins in primary-cells - changes in alpha-v-associated beta-subunits during differentiation  Academic Article
• A developmental influence of the N-methyl-D-aspartate receptor NR3A subunit on prepulse inhibition of startle  Academic Article
• A di-acidic (DxE) code directs concentration of cargo during export from the endoplasmic reticulum  Academic Article
• A di-acidic signal required for selective export from the endoplasmic reticulum  Academic Article
• A direct GABAergic output from the basal ganglia to frontal cortex  Academic Article
• A direct enzymatic assay for the esterolytic activity of activated hageman factor  Academic Article
• A direct interaction of axonin-1 with NgCAM-related cell adhesion molecule (NrCAM) results in guidance, but not growth of commissural axons  Academic Article
• A direct, plasmin-independent assay for plasminogen activator  Academic Article
• A directed molecular evolution approach to improved immunogenicity of the hiv-1 envelope glycoprotein  Academic Article
• A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAMTS9) expression by chondrocytes during endochondral ossification  Academic Article
• A distal effect of microsomal triglyceride transfer protein deficiency on the lysosomal recycling of CD1d  Academic Article
• A distinct set of drosophila brain neurons required for neurofibromatosis type 1-dependent learning and memory  Academic Article
• A distributed chemosensory circuit for oxygen preference in C. elegans  Academic Article
• A distribution-free test for tumor-growth curve analyses with application to an animal tumor-immunotherapy experiment  Academic Article
• A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid use  Academic Article
• A domain of clathrin that forms coats  Academic Article
• A dominant role for cd8+-t-lymphocyte selection in simian immunodeficiency virus sequence variation  Academic Article
• A dominant-negative mutant of c-Jun inhibits cell cycle progression during the transition of CD4(-)CD8(-) to CD4(+) CD8(+) thymocytes  Academic Article
• A dopamine d-1 agonist elevates self-stimulation thresholds: Comparison to other dopamine-selective drugs  Academic Article
• A dopamine partial agonist and antagonist block amphetamine self-administration in a progressive ratio schedule  Academic Article
• A double-blind, placebo-controlled, randomized study to evaluate the weight gain drug, mirtazapine transdermal ointment, in cats with unintended weight loss  Academic Article
• A double-stranded rna-activated protein kinase-dependent pathway mediating stress-induced apoptosis  Academic Article
• A drosophila g(1)-specific cyclin e homolog exhibits different modes of expression during embryogenesis  Academic Article
• A dual role for microglia in promoting tissue inhibitor of metalloproteinase (timp) expression in glial cells in response to neuroinflammatory stimuli  Academic Article
• A dual role for the adaptor protein DRK in Drosophila olfactory learning and memory  Academic Article
• A dual-function DNA vaccine encoding carcinoembryonic antigen and cd40 ligand trimer induces t cell-mediated protective immunity against colon cancer in carcinoembryonic antigen-transgenic mice  Academic Article
• A dynamic actin cytoskeleton functions at multiple stages of clathrin-mediated endocytosis  Academic Article
• A dynamic search process underlies microRNA targeting  Academic Article
• A dynamical study of antibody-antigen encounter reactions  Academic Article
• A dysphoric-like state during early withdrawal from extended access to methamphetamine self-administration in rats  Academic Article
• A dystroglycan mutation associated with limb-girdle muscular dystrophy  Academic Article
• A facile system for encoding unnatural amino acids in mammalian cells  Academic Article
• A factor IX-deficient mouse model for hemophilia B gene therapy  Academic Article
• A family of leukemia inhibitory factor-binding peptides that can act as antagonists when conjugated to poly(ethylene glycol)  Academic Article
• A family of lipopolysaccharide binding-proteins involved in responses to gram-negative sepsis  Academic Article
• A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange  Academic Article
• A fibronectin-like molecule is present in the developing cat cerebral cortex and is correlated with subplate neurons  Academic Article
• A fiv epitope defined by a phage peptide library screened with a monoclonal anti-fiv antibody  Academic Article
• A five-amino-acid motif in the undefined region of the tlr8 ectodomain is required for species-specific ligand recognition  Academic Article
• A flow injection renewable surface technique for cell-based drug discovery functional assays  Academic Article
• A fluorescence-based thiol quantification assay for ultra-high-throughput screening for inhibitors of coenzyme a production  Academic Article
• A fluorescent plate reader assay for ceramide kinase  Academic Article
• A fluoroacetamidine-based inactivator of protein arginine deiminase 4: Design, synthesis, and in vitro and in vivo evaluation  Academic Article
• A fluorogenic aryl fluorosulfate for intraorganellar transthyretin imaging in living cells and in Caenorhabditis elegans  Academic Article
• A fluorometric assay for red-blood-cell antibodies  Academic Article
• A focused microarray approach to functional glycomics: Transcriptional regulation of the glycome  Academic Article
• A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity  Academic Article
• A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function  Academic Article
• A fractionated cell-free system for analysis of prophase nuclear disassembly  Academic Article
• A fragment of human TrpRS as a potent antagonist of ocular angiogenesis  Academic Article
• A fully active catalytic domain of bovine aspartyl (asparaginyl) beta-hydroxylase expressed in Escherichia-coli: characterization and evidence for the identification of an active-site region in vertebrate alpha-ketoglutarate-dependent dioxygenases  Academic Article
• A function for Egf receptor signaling in expanding the developing brain in Drosophila  Academic Article
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• Action spectrum of ultraviolet light-induced damage to nuclear DNA in vivo  Academic Article
• Actions of a picomolar short-acting S1P(1) agonist in S1P(1)-eGFP knock-in mice  Academic Article
• Actions of acute and chronic ethanol on presynaptic terminals  Academic Article
• Actions of redox-related congeners of nitric oxide at the NMDA receptor  Academic Article
• Activated and memory cd8(+) t cells can be distinguished by their cytokine profiles and phenotypic markers  Academic Article
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• Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage  Academic Article
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• Activated protein C promotes neovascularization and neurogenesis in postischemic brain via protease-activated receptor 1  Academic Article
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• Activated protein C targets CD8(+) dendritic cells to reduce the mortality of endotoxemia in mice  Academic Article
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• Activating PI3-kinase to dampen inflammation  Academic Article
• Activating and anxiogenic effects of corticotropin releasing-factor are not inhibited by blockade of the pituitary-adrenal system with dexamethasone  Academic Article
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• Activating transcription factor 4 promotes angiogenesis of breast cancer through enhanced macrophage recruitment  Academic Article
• Activation and function of gamma-delta t-cells  Academic Article
• Activation and inhibition of microsomal glutathione transferase from mouse liver  Academic Article
• Activation and regulation of the Spc1 stress-activated protein kinase in Schizosaccharomyces pombe  Academic Article
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• Activation of 5-hydroxytryptamine-1a receptors increases the affinity of galanin receptors in diencephalic and telencephalic areas of the rat  Academic Article
• Activation of B lymphocytes by monovalent anti-Lyb-2 antibodies  Academic Article
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• Activation of MPF in fission yeast  Academic Article
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• Activation of Rac-1 Rac-2, and Cdc42 by hemopoietic growth factors or cross-linking of the B-lymphocyte receptor for antigen  Academic Article
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• Activation of a central noradrenergic projection to cerebellum  Academic Article
• Activation of angiogenic signaling pathways by two human tRNA synthetases  Academic Article
• Activation of apoptosis associated with enforced myc expression in myeloid progenitor cells is dominant to the suppression of apoptosis by interleukin-3 or erythropoietin  Academic Article
• Activation of b lymphocytes by locally concentrated concanavalin a  Academic Article
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• Activators of the nuclear receptor ppar gamma enhance colon polyp formation  Academic Article
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• Active forgetting of olfactory memories in Drosophila  Academic Article
• Active immunization with a glycolipid transition state analogue protects against endotoxic shock  Academic Article
• Active site mapping, biochemical properties and subcellular localization of rhodesain, the major cysteine protease of Trypanosoma brucei rhodesiense  Academic Article
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• Actively transcribed genes in the raf oncogene group, located on the x-chromosome in mouse and human  Academic Article
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• Activity-based probes that target diverse cysteine protease families  Academic Article
• Activity-based probes that target functional subclasses of phospholipases in proteomes  Academic Article
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• Activity-based protein profiling for the functional annotation of enzymes  Academic Article
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• Acute effects of antiglomerular basement-membrane antibody on process of glomerular-filtration in rat  Academic Article
• Acute ethanol alters calcium signals elicited by glutamate receptor agonists and K+ depolarization in cultured cerebellar Purkinje neurons  Academic Article
• Acute ethanol alters the firing pattern and glutamate response of cerebellar Purkinje neurons in culture  Academic Article
• Acute ethanol induces c-fos immunoreactivity in GABAergic neurons of the central nucleus of the amygdala  Academic Article
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• Acute immune complex disease in rabbits. The role of complement and of a leukocyte-dependent release of vasoactive amines from platelets  Academic Article
• Acute immunologic arthritis in rabbits  Academic Article
• Acute neuroprotective synergy of erythropoietin and insulin-like growth factor I  Academic Article
• Acute nicotine decreases, and chronic nicotine increases the expression of brain-derived neurotrophic factor mrna in rat hippocampus  Academic Article
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• Acute viral infection: Tissue injury mediated by anti-viral antibody through a complement effector system  Academic Article
• Acute-phase responses in transgenic mice with CNS overexpression of IL-1 receptor antagonist  Academic Article
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• Adaptation, allometry, and hypertension  Academic Article
• Adapter reagents for protein site specific dye labeling  Academic Article
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• Adaptive immune responses mediated by natural killer cells  Academic Article
• Adaptive mutations alter antibody structure and dynamics during affinity maturation  Academic Article
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• Adding new chemistries to the genetic code  Academic Article
• Addition of N-terminal peptide sequences activates the oncogenic and signaling potentials of the catalytic subunit p110α of phosphoinositide-3-kinase  Academic Article
• Addition of an alpha-hydroxy acid to the genetic code of bacteria  Academic Article
• Additional Comment on three X-ray crystal structure papers  Academic Article
• Additional intragenic promoter elements of the Xenopus 5S RNA genes upstream from the TFIIIA-binding site  Academic Article
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• Analysis of lymphocytic choriomeningitis virus gene expression in acutely and persistently infected mice  Academic Article
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• Anatomy of viral persistence: mechanisms of persistence and associated disease  Academic Article
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• Aneuploidy Causes Non-genetic Individuality  Academic Article
• Aneuploidy in the normal and diseased brain  Academic Article
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• Angiogenic capacity of M1-and M2-polarized macrophages is determined by the levels of TIMP-1 complexed with their secreted proMMP-9  Academic Article
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• Antifungal imidazoles block assembly of inducible no synthase into an active dimer  Academic Article
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• Antigen concentration and precursor frequency determine the rate of CD8+ T cell tolerance to peripherally expressed antigens  Academic Article
• Antigen delivery to macrophages using liposomal nanoparticles targeting sialoadhesin/cd169  Academic Article
• Antigen presentation and t cell development in h2-m-deficient mice  Academic Article
• Antigen presentation in retroviral vector-mediated gene transfer in vivo  Academic Article
• Antigen processing by autoreactive B cells promotes determinant spreading  Academic Article
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• Antigen receptor 'capacity' and the sensitivity of self-tolerance  Academic Article
• Antigen receptor selection by editing or downregulation of v(d)j recombination  Academic Article
• Antigen recognition by variable lymphocyte receptors  Academic Article
• Antigen-driven B cell differentiation in vivo  Academic Article
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• Antigen-processing and presentation  Academic Article
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• Antigen-specific memory B cell development  Academic Article
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• Antigen-specific t helper cell function: Differential cytokine expression in primary and memory responses  Academic Article
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• Antigenic peptides  Academic Article
• Antigenicity of myohemerythrin - response  Academic Article
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• Antigens associated with human squamous-cell lung-carcinoma defined by murine monoclonal-antibodies  Academic Article
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• Antinuclear antibodies in scleroderma  Academic Article
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• Blockade of NMDA receptor-mediated mobilization of intracellular Ca2+ prevents neurotoxicity  Academic Article
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• Blockade of endocannabinoid hydrolytic enzymes attenuates precipitated opioid withdrawal symptoms in mice  Academic Article
• Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain  Academic Article
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• Blockade of interferon Beta, but not interferon alpha, signaling controls persistent viral infection  Academic Article
• Blockade of m1 muscarinic acetylcholine receptors modulates the methamphetamine-induced psychomotor stimulant effect  Academic Article
• Blockade of nicotine self-administration with nicotinic antagonists in rats  Academic Article
• Blockade of nicotinic responses in rat retinal ganglion cells by neuronal bungarotoxin  Academic Article
• Blockade of nitric oxide synthesis reduces responding for cocaine self-administration during extinction and reinstatement  Academic Article
• Blockade of nucleus accumbens opiate receptors attenuates intravenous heroin reward in the rat  Academic Article
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• Blocking transcription through a nucleosome with synthetic DNA ligands  Academic Article
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• Blood coagulation. The thrombin paradox  Academic Article
• Blood-pressure in genetically hypertensive rats - influence of the y-chromosome  Academic Article
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• Bone marrow plasmacytoid dendritic cells can differentiate into myeloid dendritic cells upon virus infection  Academic Article
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• Catalytic antibodies  Academic Article
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• Cell-adhesion molecules  Academic Article
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• Cellular and humoral immunity in chronic equine laminitis  Academic Article
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• DNA replication checkpoint  Academic Article
• DNA replication checkpoint control  Academic Article
• DNA replication defects delay cell division and disrupt cell polarity in early Caenorhabditis elegans embryos  Academic Article
• DNA sequence-directed nucleosome reconstitution on 5S RNA genes of Xenopus-laevis  Academic Article
• DNA sequencing of the 7 remaining structural genes of the gene-cluster encoding the energy-transducing nadh-quinone oxidoreductase of paracoccus-denitrificans  Academic Article
• DNA vaccination against vegf receptor 2 reduces atherosclerosis in ldl receptor-deficient mice  Academic Article
• DNA vaccination can break immunological tolerance to prp in wild-type mice and attenuates prion disease after intracerebral challenge  Academic Article
• DNA vaccination to treat autoimmune diabetes  Academic Article
• DNA vaccination with plasmids encoding the intracellular (HBcAg) or secreted (HBeAg) form of the core protein of hepatitis B virus primes T cell responses to two overlapping Kb- and Kd-restricted epitopes  Academic Article
• DNA vaccines designed to inhibit tumor growth by suppression of angiogenesis  Academic Article
• DNA vaccines suppress tumor growth and metastases by the induction of anti-angiogenesis  Academic Article
• DNA variation and brain region-specific expression profiles exhibit different relationships between inbred mouse strains: Implications for eqtl mapping studies  Academic Article
• DNA-based vaccines activate innate and adaptive antitumor immunity by engaging the nkg2d receptor  Academic Article
• DNA-binding property of Sm nuclear antigen  Academic Article
• DNA-binding site for two skeletal actin promoter factors is important for expression in muscle cells  Academic Article
• DNA-dependent protein kinase inhibitors as drug candidates for the treatment of cancer  Academic Article
• DNA-fingerprinting by sampled sequencing  Academic Article
• DNA-repair proteins  Academic Article
• DNA-sequences preceding the rabbit beta-globin gene are required for formation in mouse l cells of beta-globin rna with the correct 5' terminus  Academic Article
• DOLORS: versatile strategy for internal labeling and domain localization in electron microscopy  Academic Article
• DPP8 and DPP9 expression in cynomolgus monkey and Sprague Dawley rat tissues  Academic Article
• DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis  Academic Article
• DPP9 enzyme activity controls survival of mouse migratory tongue muscle progenitors and its absence leads to neonatal lethality due to suckling defect  Academic Article
• DST4 - a new, and probably the last, functional DH gene in the BALB/c mouse  Academic Article
• DUBs, the regulation of cell identity and disease  Academic Article
• Dab1 is required for synaptic plasticity and associative learning  Academic Article
• Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during drosophila development  Academic Article
• Daily eating patterns and their impact on health and disease  Academic Article
• Daily scheduled high fat meals moderately entrain behavioral anticipatory activity, body temperature, and hypothalamic c-Fos activation  Academic Article
• Daring to learn from humanized mice  Academic Article
• Darwinian evolution of prions in cell culture  Academic Article
• Data-driven synthesis of proteolysis-resistant peptide hormones  Academic Article
• Database searching using mass spectrometry data  Academic Article
• De novo KCNB1 mutations in epileptic encephalopathy  Academic Article
• De novo generation of a transmissible spongiform encephalopathy by mouse transgenesis  Academic Article
• De-etiolated 1 and damaged DNA binding protein 1 interact to regulate Arabidopsis photomorphogenesis  Academic Article
• Deae-dextran: Enhancement of cellular transformation induced by avian sarcoma viruses  Academic Article
• Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function  Academic Article
• Death-associated proteins: from gene identification to the analysis of their apoptotic and tumour suppressive functions  Academic Article
• Decay-accelerating factor 1 (daf1) deficiency exacerbates xenobiotic-induced autoimmunity  Academic Article
• Deciphering the interaction of the corticotropin-releasing factor and serotonin brain systems in anxiety-related disorders  Academic Article
• Deconstructing transcriptional heterogeneity in pluripotent stem cells  Academic Article
• Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo  Academic Article
• Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression, and apoptosis in mice lacking fatty acid amide hydrolase  Academic Article
• Decreased aggression and increased repetitive behavior in Pten haploinsufficient mice  Academic Article
• Decreased apoptosis in proliferative and postmitotic regions of the Caspase 3-deficient embryonic central nervous system  Academic Article
• Decreased brain reward function during nicotine withdrawal in c57bl6 mice: Evidence from intracranial self-stimulation (icss) studies  Academic Article
• Decreased brain reward produced by ethanol withdrawal  Academic Article
• Decreased immobility in swimming test by homologous interferon-alpha in mice accompanied with increased cerebral tryptophan level and serotonin turnover  Academic Article
• Decreased phospho-Akt signaling in a mouse model of total parenteral nutrition: a potential mechanism for the development of intestinal mucosal atrophy  Academic Article
• Decreased response to acetylcholine during aging of aplysia neuron R15  Academic Article
• Dedifferentiation of lineage-committed cells by a small molecule  Academic Article
• Deep proteome mapping of mouse kidney based on OFFGel prefractionation reveals remarkable protein post- translational modifications  Academic Article
• Deep sequencing of the murine Igh repertoire reveals complex regulation of nonrandom V gene rearrangement frequencies  Academic Article
• Deep sequencing reveals cell-type-specific patterns of single-cell transcriptome variation  Academic Article
• Deep-brain magnetic stimulation promotes adult hippocampal neurogenesis and alleviates stress-related behaviors in mouse models for neuropsychiatric disorders  Academic Article
• Defect in cyclic AMP phosphodiesterase due to the dunce mutation of learning in Drosophila melanogaster  Academic Article
• Defective CD8+ T cell peripheral tolerance in nonobese diabetic mice  Academic Article
• Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene  Academic Article
• Defective dimerization of von Willebrand factor subunits due to a Cys -> Arg mutation in type IID von Willebrand disease  Academic Article
• Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice  Academic Article
• Defective lymphotoxin-β receptor-induced NF-κB transcriptional activity in NIK-deficient mice  Academic Article
• Defective transport of the obesity mutant PC1/3 N222D contributes to loss of function  Academic Article
• Defectiveness of avian myelocytomatosis virus mc29 - isolation of long-term nonproducer cultures and analysis of virus-specific polypeptide-synthesis  Academic Article
• Defects in deletional tolerance of CD8+ T cells in autoimmune diabetes  Academic Article
• Defects in skin γδ T cell function contribute to delayed wound repair in rapamycin-treated mice  Academic Article
• Defects in the acquisition of CD8 T cell effector function after priming with tumor or soluble antigen can be overcome by the addition of an OX40 agonist  Academic Article
• Defensive spiroketals from Asceles glaber (Phasmatodea): absolute configuration and effects on ants and mosquitoes  Academic Article
• Deficiencies in tRNA synthetase editing activity cause cardioproteinopathy  Academic Article
• Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances  Academic Article
• Deficiency of DNA repair nuclease ERCC1-XPF promotes prostate cancer progression in a tissue recombination model  Academic Article
• Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis  Academic Article
• Deficiency of lrp8 in mice is associated with altered platelet function and prolonged time for in vivo thrombosis  Academic Article
• Deficiency of the cyclin kinase inhibitor P21(WAF-1/CIP-1) promotes apoptosis of activated/memory T cells and inhibits spontaneous systemic autoirnmunity  Academic Article
• Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the pkr gene: Role of irf-1 and nf-kappa b  Academic Article
• Deficient ghrelin receptor-mediated signaling compromises thymic stromal cell microenvironment by accelerating thymic adiposity  Academic Article
• Deficient signaling in mice devoid of double-stranded rna-dependent protein kinase  Academic Article
• Deficits in discriminated learning remain despite clearance of long-term persistent viral infection in mice  Academic Article
• Deficits in tolerance to ethanol in brattleboro rats  Academic Article
• Defined and scalable differentiation of human oligodendrocyte precursors from pluripotent stem cells in a 3D culture system  Academic Article
• Defined topologically-complex protein matrices to manipulate cell shape via three-dimensional fiber-like patterns  Academic Article
• Defining HIV-1 protease substrate selectivity  Academic Article
• Defining actin filament length in striated muscle: rulers and caps or dynamic stability?  Academic Article
• Defining antibody-antigen recognition: towards engineered antibodies and epitopes  Academic Article
• Defining criteria for oligomannose immunogens for HIV using icosahedral virus capsid scaffolds  Academic Article
• Defining parameters for successful immunocytotherapy of persistent viral infection  Academic Article
• Defining subsets of naive and memory B cells based on the ability of their progeny to somatically mutate in vitro  Academic Article
• Defining the conformational features of anchorless, poorly neuroinvasive prions  Academic Article
• Defining the critical hypoxic threshold that promotes vascular remodeling in the brain  Academic Article
• Defining the immune mechanism with monoclonal antibodies  Academic Article
• Defining the metabolome: size, flux, and regulation  Academic Article
• Defining the pathogenic involvement of desmoglein 4 in pemphigus and staphylococcal scalded skin syndrome  Academic Article
• Defining the risks of mesenchymal stromal cell therapy  Academic Article
• Definition of 2 angiogenic pathways by distinct alpha(v) integrins  Academic Article
• Definition of IFN-γ-related pathways critical for chemically-induced systemic autoimmunity  Academic Article
• Definition of the binding-sites of individual zinc fingers in the transcription factor-IIIA-5S RNA gene-complex  Academic Article
• Degeneracy and complexity in biological systems  Academic Article
• Degenerative effects of 6-aminodopamine and 6-hydroxydopamine on peripheral adrenergic nerves  Academic Article
• Degradable conjugates from oxanorbornadiene reagents  Academic Article
• Degradation, foraging, and depletion of mucus sialoglycans by the vagina-adapted Actinobacterium Gardnerella vaginalis  Academic Article
• Dehydroepiandrosterone-sulfate alters synaptic potentials in area CA1 of the hippocampal slice  Academic Article
• Delayed administration of anti-PD-1 antibody reverses immune dysfunction and improves survival during sepsis  Academic Article
• Delayed administration of memantine prevents N-methyl-D-aspartate receptor-mediated neurotoxicity  Academic Article
• Delayed and accelerated aging share common longevity assurance mechanisms  Academic Article
• Delayed cutaneous hypersensitivity to cell-free tumor antigens  Academic Article
• Delayed satiety-like actions and altered feeding microstructure by a selective type 2 corticotropin-releasing factor agonist in rats: Intra-hypothalamic urocortin 3 administration reduces food intake by prolonging the post-meal interval  Academic Article
• Deletion mutants of human interleukin 1β with significantly reduced agonist properties: Search for the agonist/antagonist switch in ligands to the interleukin 1 receptors  Academic Article
• Deletion of IgG-switched autoreactive B cells and defects in Fas(lpr) lupus mice  Academic Article
• Deletion of LRP5 in VLDLR knockout mice inhibits retinal neovascularization  Academic Article
• Deletion of MyD88 markedly attenuates sepsis-induced T and B lymphocyte apoptosis but worsens survival  Academic Article
• Deletion of PREPl causes growth impairment and hypotonia in mice  Academic Article
• Deletion of amino acids glu146 -> arg160 in human apolipoprotein a-i (apoa-i-seattle) alters lecithin : Cholesterol acyltransferase activity and recruitment of cell phospholipid  Academic Article
• Deletion of ghrelin impairs neither growth nor appetite  Academic Article
• Deletion of lysophosphatidic acid receptor LPA1 reduces neurogenesis in the mouse dentate gyrus  Academic Article
• Deletion of naive CD8 T cells requires persistent antigen and is not programmed by an initial signal from the tolerogenic APC  Academic Article
• Deletion of nef slows but does not prevent CD4-positive T-cell depletion in human immunodeficiency virus type 1-infected human-PBL-SCID mice  Academic Article
• Deletion of p21 (WAF-1/Cip1) does not induce systemic autoimmunity in female BXSB mice  Academic Article
• Deletion of the nucleotide excision repair gene ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions  Academic Article
• Deletions linked to TP53 loss drive cancer through p53-independent mechanisms  Academic Article
• Deletions within the 5 ' utr of coxsackievirus b3: Consequences for virus translation and replication  Academic Article
• Deliberate removal of T cell help improves virus-neutralizing antibody production  Academic Article
• Delineating the susceptibility of botulinum neurotoxins to denaturation through thermal effects  Academic Article
• Delineation of a defect in t-cell receptor beta-genes of nzw mice predisposed to autoimmunity  Academic Article
• Delineation of spontaneous erythrocyte autoantibody responses of nzb and other strains of mice  Academic Article
• Delineation of the peptide binding site of the human galanin receptor  Academic Article
• Delineation of the proinflammatory cytokine cascade in fever induction  Academic Article
• Delivering quantum dot-peptide bioconjugates to the cellular cytosol: escaping from the endolysosomal system  Academic Article
• Delivering the kiss of death: Progress on understanding how perforin works  Academic Article
• Delivery and tracking of quantum dot peptide bioconjugates in an intact developing avian brain  Academic Article
• Delivery of proteases in aqueous two-phase systems enables direct purification of stem cell colonies from feeder cell co-cultures for differentiation into functional cardiomyocytes  Academic Article
• Delta(9)-tetrahydrocannabinol attenuates mdma-induced hyperthermia in rhesus monkeys  Academic Article
• Delta(9)-tetrahydrocannabinol immunochemical studies: Haptens, monoclonal antibodies, and a convenient synthesis of radiolabeled delta(9)-tetrahydrocannabinol  Academic Article
• Delta(9)tetrahydrocannabinol impairs visuo-spatial associative learning and spatial working memory in rhesus macaques  Academic Article
• Delta-9,11 modification of glucocorticoids dissociates nuclear factor-κB inhibitory efficacy from glucocorticoid response element-associated side effects  Academic Article
• Delta-9-tetrahydrocannabinol stimulates ABP secretion from rat Sertoli cells in vitro  Academic Article
• Demonstration of a hematopoietic stem-cell antigen (SC-1) on a murine lymphoma and isolation of variants lacking the antigen  Academic Article
• Demonstration of an extensive tras-tubular network continuous with the golgi-apparatus stack that may function in glycosylation  Academic Article
• Demonstration of dehydrogenases and monoamine-oxidase by formation of osmium blacks at sites of hatchetts brown  Academic Article
• Demonstration of developmental anomalies in mouse fetuses by transfer of murine cytomegalovirus DNA-injected eggs to surrogate mothers  Academic Article
• Demonstration of direct effects of growth hormone on neonatal cardiomyocytes  Academic Article
• Demonstration of functional similarity of proposed biosimilar ABP 501 to adalimumab  Academic Article
• Demonstration of muscarinic acetylcholine receptor-like immunoreactivity in the rat forebrain and upper brain-stem  Academic Article
• Demonstration that orf2 encodes the feline immunodeficiency virus transactivating (tat) protein and characterization of a unique gene product with partial rev activity  Academic Article
• Denaturant-induced stimulation of the beta-migrating plasminogen activator inhibitor in endothelial cells and serum  Academic Article
• Dendrite growth increased by visual activity requires NMDA receptor and Rho GTPases  Academic Article
• Dendritic BDNF synthesis is required for late-phase spine maturation and recovery of cortical responses following sensory deprivation  Academic Article
• Dendritic arbor development and synaptogenesis  Academic Article