subject area of

• 'Random coil' (1)H chemical shifts obtained as a function of temperature and trifluoroethanol concentration for the peptide series GGXGG  Academic Article
• (-)-2-oxa-4-aminobicylco[3.1.0]hexane-4,6-dicarboxylic acid (LY379268) and 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]piperidine (MTEP) similarly attenuate stress-induced reinstatement of cocaine seeking  Academic Article
• 3'-5' exonuclease of Klenow fragment: role of amino acid residues within the single-stranded DNA binding region in exonucleolysis and duplex DNA melting  Academic Article
• A bacterial and silkworm aminoacyl-tRNA synthetase have a common epitope which maps to the catalytic domain of each  Academic Article
• A bacterial strain with a unique quadruplet codon specifying non-native amino acids  Academic Article
• A biosynthetic approach for the incorporation of unnatural amino acids into proteins  Academic Article
• A chemical toolkit for proteins: an expanded genetic code  Academic Article
• A distal mutation perturbs dynamic amino acid networks in dihydrofolate reductase  Academic Article
• A facile system for encoding unnatural amino acids in mammalian cells  Academic Article
• A general method for greatly improving the affinity of antibodies by using combinatorial libraries  Academic Article
• A general method for site-specific incorporation of unnatural amino acids into proteins  Academic Article
• A genetic marker in the variable region of light chains of mouse immunoglobulins  Academic Article
• A genetically encoded aza-Michael acceptor for covalent cross-linking of protein-receptor complexes  Academic Article
• A genetically encoded fluorescent amino acid  Academic Article
• A genetically encoded fluorescent amino acid  Academic Article
• A heterocyclic peptide nanotube  Academic Article
• A highly enantioselective amino acid-catalyzed route to functionalized alpha-amino acids  Academic Article
• A highly enantioselective route to either enantiomer of both alpha- and beta-amino acid derivatives  Academic Article
• A homolog of alpha-2-macroglobulin purified from the hemolymph of the horseshoe-crab limulus-polyphemus  Academic Article
• A membrane-embedded amino acid couples the SpoIIQ channel protein to anti-sigma factor transcriptional repression during Bacillus subtilis sporulation  Academic Article
• A mutation in the small (alpha) subunit of glycyl-tRNA synthetase affects amino acid activation and subunit association parameters  Academic Article
• A neural cell-adhesion molecule from human-brain  Academic Article
• A phage display system with unnatural amino acids  Academic Article
• A plausible simultaneous synthesis of amino acids and simple peptides on the primordial Earth  Academic Article
• A protein.protein interaction platform involved in recruitment of GLD-3 to the FBF.Fem-3 mRNA complex  Academic Article
• A route to enantiopure RNA precursors from nearly racemic starting materials  Academic Article
• A single amino acid substitution confers progesterone 6 beta-hydroxylase activity to rabbit cytochrome P450 2C3  Academic Article
• A source of response regulator autophosphatase activity: The critical role of a residue adjacent to the spo0f autophosphorylation active site  Academic Article
• A tryptophanyl-tRNA synthetase/tRNA pair for unnatural amino acid mutagenesis in E. coli  Academic Article
• A versatile platform for single- and multiple-unnatural amino acid mutagenesis in Escherichia coli  Academic Article
• APSY-NMR with proteins: practical aspects and backbone assignment  Academic Article
• ATP and the core "alpha-crystallin" domain of the small heat-shock protein alpha B-crystallin  Academic Article
• Abalone lysin: The dissolving and evolving sperm protein  Academic Article
• Ability of tetrahydrobiopterin analogues to support catalysis by inducible nitric oxide synthase: Formation of a pterin radical is required for enzyme activity  Academic Article
• Activation of group II metabotropic glutamate receptors attenuates both stress and cue-induced ethanol-seeking and modulates c-fos expression in the hippocampus and amygdala  Academic Article
• Acyl coenzyme A dehydrogenases and electron-transferring flavoprotein from beef heart mitochondria  Academic Article
• Adding amino acids to the genetic repertoire  Academic Article
• Adding amino acids with novel reactivity to the genetic code of Saccharomyces cerevisiae  Academic Article
• Adding new chemistries to the genetic code  Academic Article
• Addition of a photocrosslinking amino acid to the genetic code of Escherichia coli  Academic Article
• Alanine scan of [L-Dap2]ramoplanin A2 aglycon:  Assessment of the importance of each residue  Academic Article
• Allosteric control of ligand selectivity between estrogen receptors alpha and beta: Implications for other nuclear receptors  Academic Article
• Alterations of the regiospecificity of progesterone metabolism by the mutagenesis of two key amino acid residues in rabbit cytochrome P450 2C3v  Academic Article
• Amide proton-exchange and surface conformation of the basic pancreatic trypsin-inhibitor in solution - studies with two-dimensional nuclear magnetic-resonance  Academic Article
• Amino acid biosynthesis in the halophilic archaeon haloarcula hispanica  Academic Article
• Amino acid catalyzed direct asymmetric aldol reactions: A bioorganic approach to catalytic asymmetric carbon-carbon bond-forming reactions  Academic Article
• Amino acid dependent formation of phosphate anhydrides in water mediated by carbonyl sulfide  Academic Article
• Amino acid derived quinazolines as Rock/PKA inhibitors  Academic Article
• Amino acid incorporation into rat brain proteins during spreading cortical depression  Academic Article
• Amino acid residues associated with cluster n3 in the nuof subunit of the proton-translocating nadh-quinone oxidoreductase from escherichia coli  Academic Article
• Amino acid residues critical for differential inhibition of CYP2B4, CYP2B5, and CYP2B1 by phenylimidazoles  Academic Article
• Amino acid sequence of rabbit pneumococcal antibody. I. Light-chain cysteine-containing peptides  Academic Article
• Amino acid signaling to mTOR mediated by inositol polyphosphate multikinase  Academic Article
• Amino acid substitution at the dimeric interface of human manganese superoxide dismutase  Academic Article
• Amino acids that specify structure through hydrophobic clustering and histidine-aromatic interactions lead to biologically active peptidomimetics  Academic Article
• Amino terminal sequence ambiguity in 3 capsid polypeptides of poliovirus  Academic Article
• Aminoacyl-S-enzyme intermediates in β-hydroxylations and α,β-desaturations of amino acids in peptide antibiotics  Academic Article
• Aminoacylation of RNA oligonucleotides: minimalist structures and origin of specificity  Academic Article
• An efficient system for the evolution of aminoacyl-tRNA synthetase specificity  Academic Article
• An enhanced system for unnatural amino acid mutagenesis in E. coli  Academic Article
• An expanded eukaryotic genetic code  Academic Article
• An expanded genetic code with a functional quadruplet codon  Academic Article
• An expanding genetic code  Academic Article
• An expanding genetic code  Academic Article
• An expedient route to the tetrazole analogues of alpha-amino acids  Academic Article
• An experimental approach to evaluating the role of backbone interactions in proteins using unnatural amino acid mutagenesis  Academic Article
• An improved system for the generation and analysis of mutant proteins containing unnatural amino acids in Saccharomyces cerevisiae  Academic Article
• An investigation of specific interactions of deoxyribonucleic acid and lysine-rich (F1) histone preparations  Academic Article
• An operational RNA code for amino acids and possible relationship to genetic code  Academic Article
• An α/β-peptide helix bundle with a pure β3-amino acid core and a distinctive quaternary structure  Academic Article
• Analysis of large-scale mutagenesis data to assess the impact of single amino acid substitutions  Academic Article
• Antibody conjugates with unnatural amino acids  Academic Article
• Arteriovenous blood metabolomics: a readout of intra-tissue metabostasis  Academic Article
• Assignment of heme and distal amino-acid resonances in the h-1-NMR spectra of the carbon-monoxide and oxygen complexes of sperm whale myoglobin  Academic Article
• Assignment of the h-1 nuclear magnetic-resonance spectrum of the proteinase inhibitor-iia from bull seminal plasma by two-dimensional nuclear magnetic-resonance at 500 mhz  Academic Article
• Assignment of the h-1 nuclear magnetic-resonance spectrum of the trypsin-inhibitor homologue-k from dendroaspis-polylepis-polylepis - 2 dimensional nuclear magnetic-resonance at 360 and 500 mhz  Academic Article
• Asymmetric NHC-catalyzed aza-Diels-Alder reactions: highly enantioselective route to α-amino acid derivatives and DFT calculations  Academic Article
• Asymmetric synthesis of quaternary alpha- and beta-amino acids and beta-lactams via proline-catalyzed mannich reactions with branched aldehyde donors  Academic Article
• Asymmetric synthesis β-hydroxy amino acids via aldol reactions catalyzed by chiral ammonium salts  Academic Article
• Atomic and residue hydrophilicity in the context of folded protein structures  Academic Article
• Autoantibodies to the presumptive cytoplasmic domain of platelet glycoprotein IIIa in patients with chronic immune thrombocytopenic purpura  Academic Article
• Automated amino acid side-chain NMR assignment of proteins using 13C- and 15N-resolved 3D [1H,1H]-NOESY  Academic Article
• Aza-amino acid scanning of chromobox homolog 7 (CBX7) ligands  Academic Article
• Behavioral and functional evidence of metabotropic glutamate receptor 2/3 and metabotropic glutamate receptor 5 dysregulation in cocaine-escalated rats: Factor in the transition to dependence  Academic Article
• Betidamino acid scan of the gnrh antagonist acyline  Academic Article
• Beyond the canonical 20 amino acids: expanding the genetic lexicon  Academic Article
• Binding and functional properties of concanavalin-a and its derivatives .2. Proteolytic product with saccharide-binding activity  Academic Article
• Binding of β4γ5 by adenosine A1 and A2A receptors determined by stable isotope labeling with amino acids in cell culture and mass spectrometry  Academic Article
• Biochemical characterization of the Caenorhabditis elegans FBF. CPB-1 translational regulation complex identifies conserved protein interaction hotspots  Academic Article
• Biochemical comparison of lens crystallins from three reptilian species  Academic Article
• Biological applications of expanded genetic codes  Academic Article
• Biosynthesis of the beta-amino acid moiety of the enediyne antitumor antibiotic c-1027 featuring beta-amino acyl-s-carrier protein intermediates  Academic Article
• Biosynthesis of the unique amino acid side chain of butirosin: possible protective-group chemistry in an acyl carrier protein-mediated pathway  Academic Article
• Biosynthetic method for introducing unnatural amino acids site-specifically into proteins  Academic Article
• Biosynthetic n-15 and c-13 isotope labeling of glutathione in the mixed disulfide with escherichia-coli glutaredoxin documented by sequence-specific NMR assignments  Academic Article
• Broadly neutralizing DNA vaccine with specific mutation alters the antigenicity and sugar-binding activities of influenza hemagglutinin  Academic Article
• Calcitonin gene-related peptide is metabolized by an endopeptidase hydrolyzing substance-p  Academic Article
• Carbon-13 nuclear magnetic-resonance studies on (85 percent 13C-enriched Gly9) oxytocin  Academic Article
• Carbonyl sulfide-mediated prebiotic formation of peptides  Academic Article
• Carboxy-terminal five amino acids of the nucleocapsid protein of vesicular stomatitis virus are required for encapsidation and replication of genome rna  Academic Article
• Cassette mutagenesis of a potential substrate recognition region of cytochrome P450 2C2  Academic Article
• Central limit theorem as an approximation for intensity-based scoring function  Academic Article
• Characterization of glutathione reductase from porcine erythrocytes  Academic Article
• Characterization of glyoxalase I purified from pig erythrocytes by affinity chromatography  Academic Article
• Characterization of renal amyloid derived from the variable region of the lambda light chain subgroup-II  Academic Article
• Characterization of sheep prolactin  Academic Article
• Characterization of the aminocarboxycyclopropane-forming enzyme CmaC  Academic Article
• Characterization of the covalent binding of thiostrepton to a thiostrepton-induced protein from streptomyces lividans  Academic Article
• Characterization of zebrafish caspase-3 and induction of apoptosis through ceramide generation in fish fathead minnow tailbud cells and zebrafish embryo  Academic Article
• Chemical and immunochemical characterization of electrophoretic subfractions of rabbit gammag-immunoglobulin light chains with b4 allotypic specificity  Academic Article
• Chemical and immunochemical evidence for different classes of rabbit light polypeptide chains  Academic Article
• Chemical approaches for the detection and synthesis of acetylated proteins  Academic Article
• Chemical characterization of a neural cell-adhesion molecule purified from embryonic brain membranes  Academic Article
• Chemical circuitry and central cardiovascular regulation  Academic Article
• Chemical markers of transplantation individuality solubilized with sonic energy  Academic Article
• Chemical modification of viruses and virus-like particles  Academic Article
• Chemical synthesis of a glycoprotein having an intact human complex-type sialyloligosaccharide under the Boc and Fmoc synthetic strategies  Academic Article
• Chemistry of periodate-mediated cross-linking of 3,4-dihydroxylphenylalanine-containing molecules to proteins  Academic Article
• Chiral-selective aminoacylation of an RNA minihelix  Academic Article
• Chiral-selective aminoacylation of an RNA minihelix: mechanistic features and chiral suppression  Academic Article
• Chlamydia species-dependent differences in the growth requirement for lysosomes  Academic Article
• Cholinergic mechanisms in the reticular control of transmission in the cat lateral geniculate-nucleus  Academic Article
• Chronic exposure to alcohol during development alters the responses to excitatory amino-acids in cultured Purkinje neurons  Academic Article
• Cluster analysis of aminoacyl-tRNAs from mouse plasmacytomas correlates chromatographic profiles with myeloma protein similarity, clonal origin of tumour lines, and the neoplastic nature of the tissues  Academic Article
• Combined functional and immunochemical analysis of normal and abnormal human factor-x  Academic Article
• Comparison of glyoxalase I purified from yeast (Saccharomyces cerevisiae) with the enzyme from mammalian sources  Academic Article
• Complementary use of chemical modification and site-directed mutagenesis to probe structure activity relationships in enzymes  Academic Article
• Computational design of an unnatural amino acid dependent metalloprotein with atomic level accuracy  Academic Article
• Computational design of multinuclear metalloproteins using unnatural amino acids  Academic Article
• Computational prediction of N-linked glycosylation incorporating structural properties and patterns  Academic Article
• Conditional lethal mutants of avian sarcoma viruses. Ii. Analysis of the temperature-sensitive lesion in ts 75  Academic Article
• Conformation of the carboxy-terminal region of the a-alpha chain of fibrinogen as elucidated by immunochemical analyses  Academic Article
• Conformational sampling by NMR solution structures calculated with the program diana evaluated by comparison with long-time molecular dynamics calculations in explicit water  Academic Article
• Conserved amino acid residues of the NuoD segment important for structure and function of Escherichia coli NDH-1 (complex I)  Academic Article
• Contribution of aromatic interactions to alpha-helix stability  Academic Article
• Contribution of charged amino acids in the CDR2 region of CD4 to HIV-1 gp120 binding  Academic Article
• Contribution of five amino acid residues in the glutathione-binding site to the function of human glutathione transferase P1-1  Academic Article
• Controlling amyloid beta-peptide fibril formation with protease-stable ligands  Academic Article
• Controlling the architecture, coordination, and reactivity of nanoparticle coating utilizing an amino acid central scaffold  Academic Article
• Correlations between internal mobility and stability of globular-proteins  Academic Article
• Covalent and 3-dimensional structure of concanavalin-a .1. Amino-acid sequence of cyanogen-bromide fragments f1 and f2  Academic Article
• Covalent and 3-dimensional structure of concanavalin-a .2. Amino-acid sequence of cyanogen-bromide fragment f3  Academic Article
• Cryopreservation of postnatal rat retinal ganglion cells: persistence of voltage- and ligand-gated ionic currents  Academic Article
• Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesis  Academic Article
• Crystallization of a small fragment of an aminoacyl tRNA synthetase  Academic Article
• Crystallographic and biochemical analysis of cocaine-degrading antibody l5a10  Academic Article
• Cysteine-mediated redox signaling: chemistry, biology, and tools for discovery  Academic Article
• Cytochrome-oxidase genes from thermus-thermophilus - nucleotide-sequence and analysis of the deduced primary structure of subunit-iic of cytochrome-caa3  Academic Article
• Degradable conjugates from oxanorbornadiene reagents  Academic Article
• Designing sequence to control protein function in an EF-hand protein  Academic Article
• Detecting individual sites subject to episodic diversifying selection  Academic Article
• Determination of the nuclear-magnetic-resonance solution structure of the DNA-binding domain (residues 1 to 69) of the 434 repressor and comparison with the x-ray crystal-structure  Academic Article
• Developing ligands for palladium(II)-catalyzed C-H functionalization: intimate dialogue between ligand and substrate  Academic Article
• Development and optimization of Glaser-Hay bioconjugations  Academic Article
• Development of a simple method for protein conjugation by copper-free click reaction and its application to antibody-free Western blot analysis  Academic Article
• Development of improved tRNAs for in vitro biosynthesis of proteins containing unnatural amino acids  Academic Article
• Development of new enzymatic catalysts for peptide-synthesis in aqueous and organic-solvents  Academic Article
• Development of selective tight-binding inhibitors of leukotriene-a4 hydrolase  Academic Article
• Developmental expression of excitatory amino-acid responses in cerebellar Purkinje neurons in culture  Academic Article
• Developmentally regulated proteins of plasma-membrane of dictyostelium-discoideum - carbohydrate-binding protein  Academic Article
• Differences in the amino acid compositions of allogeneic guinea pig transplantation antigens  Academic Article
• Dipole moments in relation to configuration of polypeptide chains  Academic Article
• Direct amino acid-catalyzed asymmetric desymmetrization of meso-compounds: Tandem aminoxylation/o-n bond heterolysis reactions  Academic Article
• Direct asymmetric anti-mannich-type reactions catalyzed by a designed amino acid  Academic Article
• Direct organocatalytic asymmetric aldol reactions of alpha-amino aldehydes: Expedient syntheses of highly enantiomerically enriched anti-beta-hydroxy-alpha-amino acids  Academic Article
• Direct organocatalytic asymmetric heterodomino reactions: The knoevenagel/diels-alder/epimerization sequence for the highly diastereoselective synthesis of symmetrical and nonsymmetrical synthons of benzoannelated centropolyquinanes  Academic Article
• Direct protein-protein conjugation by genetically introducing bioorthogonal functional groups into proteins  Academic Article
• Directed evolution of d-sialic acid aldolase to l-3-deoxy-manno-2-octulosonic acid (l-kdo) aldolase  Academic Article
• Disparate proteome reactivity profiles of carbon electrophiles  Academic Article
• Dissecting the specificity of protein-protein interaction in bacterial two-component signaling: Orphans and crosstalks  Academic Article
• Diverging catalytic capacities and selectivity profiles with haloalkane substrates of chimeric alpha class glutathione transferases  Academic Article
• Diverse functional evolution of serine decarboxylases: identification of two novel acetaldehyde synthases that uses hydrophobic amino acids as substrates  Academic Article
• Diversity of light chain variable region sequences among rabbit antibodies elicited by same antigens  Academic Article
• Dynamic synaptic communication - finding vocabulary  Academic Article
• Dynamics of aromatic amino-acid residues in globular conformation of basic pancreatic trypsin-inhibitor (bpti) .1. H-1 NMR-studies  Academic Article
• Dynamics of aromatic amino-acid residues in globular conformation of basic pancreatic trypsin-inhibitor (bpti) .2. Semiempirical energy calculations  Academic Article
• Effect of single and repeated methamphetamine treatment on neurotransmitter release in substantia nigra and neostriatum of the rat  Academic Article
• Effects of mutations on the partitioning of DNA substrates between the polymerase and 3 '-5 ' exonuclease sites of DNA polymerase i (klenow fragment)  Academic Article
• Effects of the mGlu2/3 agonist LY379268 and the mGlu5 antagonist MTEP on ethanol seeking and reinforcement are differentially altered in rats with a history of ethanol dependence  Academic Article
• Efficient access to highly pure β-amyloid peptide by optimized solid-phase synthesis  Academic Article
• Efficient and site-specific antibody labeling by strain-promoted azide-alkyne cycloaddition  Academic Article
• Efficient incorporation of unnatural amino acids into proteins in Escherichia coli  Academic Article
• Efficient viral delivery system for unnatural amino acid mutagenesis in mammalian cells  Academic Article
• Electrostatic contributions to protein-protein interactions: Fast energetic filters for docking and their physical basis  Academic Article
• Elevated glutamate levels in the vitreous body of humans and monkeys with glaucoma  Academic Article
• Emergence of a single solid chiral state from a nearly racemic amino acid derivative  Academic Article
• Emergence of solution-phase homochirality via crystal engineering of amino acids  Academic Article
• Engineered disulfide-forming amino acid substitutions interfere with a conformational change in the mismatch recognition complex Msh2-Msh6 required for mismatch repair  Academic Article
• Enhanced sensitivity to attenuation of conditioned reinstatement by the mGluR 2/3 agonist LY379268 and increased functional activity of mGluR 2/3 in rats with a history of ethanol dependence  Academic Article
• Envelope: Interactive software for modeling and fitting complex isotope distributions  Academic Article
• Erythrocyte membrane tropomyosin. Purification and properties  Academic Article
• Ether-directed ortho-c-h olefination with a palladium(ii)/monoprotected amino acid catalyst  Academic Article
• Evaluation of molecular modeling of agonist binding in light of the crystallographic structure of an agonist-bound A₂A adenosine receptor  Academic Article
• Evidence for a post-translational modification, aspartyl aldehyde, in a photosynthetic membrane protein  Academic Article
• Evidence that type 1 plasminogen activator inhibitor binds to the somatomedin B domain of vitronectin  Academic Article
• Evolution of amber suppressor tRNAs for efficient bacterial production of proteins containing nonnatural amino acids  Academic Article
• Evolution of cyclic peptide protease inhibitors  Academic Article
• Evolution of multiple, mutually orthogonal prolyl-tRNA synthetase/tRNA pairs for unnatural amino acid mutagenesis in Escherichia coli  Academic Article
• Evolution of solid phase homochirality for a proteinogenic amino acid  Academic Article
• Excess of rare amino acid polymorphisms in the toll-like receptor 4 in humans  Academic Article
• Excessive ethanol drinking following a history of dependence: Animal model of allostasis  Academic Article
• Exiting an RNA world  Academic Article
• Explicit water near the catalytic I helix Thr in the predicted solution structure of CYP2A4  Academic Article
• Exploring the potential impact of an expanded genetic code on protein function  Academic Article
• Expression and characterization of the flavoprotein subcomplex composed of 50-kda (nqo1) and 25-kda (nqo2) subunits of the proton-translocating nadh-quinone oxidoreductase of paracoccus denitrificans  Academic Article
• Extended sugar-assisted glycopeptide ligations: Development, scope, and applications  Academic Article
• Extensive sequence differences in rabbit light-chains of allotype b4 and b9  Academic Article
• FRET-based analysis of protein-nucleic acid interactions by genetically incorporating a fluorescent amino acid  Academic Article
• Fluorescent probes for conformational states of proteins. Iv. The pepsinogen-pepsin conversion  Academic Article
• Fmoc solid phase synthesis of polyamides containing pyrrole and imidazole amino acids  Academic Article
• Formation of complement subcomponent c1q immunoglobulin-g complex - thermodynamic and chemical-modification studies  Academic Article
• Fullerene-derivatized amino acids: synthesis, characterization, antioxidant properties, and solid-phase peptide synthesis  Academic Article
• Functional and mechanistic analyses of biomimetic aminoacyl transfer reactions in de novo designed coiled coil peptides via rational active site engineering  Academic Article
• Further characterization of human erythrocyte superoxide-dismutase  Academic Article
• Gamma heavy-chain disease in man - synthesis of a deleted gamma-3 immunoglobulin by lymphoid-cells in short and long-term tissue-culture  Academic Article
• Genetic and structural characterization of an amino acid dimorphism in glycoprotein Ib alpha involved in platelet transfusion refractoriness  Academic Article
• Genetic incorporation of multiple unnatural amino acids into proteins in mammalian cells  Academic Article
• Genetic incorporation of recycled unnatural amino acids  Academic Article
• Genetic incorporation of unnatural amino acids into proteins in mammalian cells  Academic Article
• Genetic introduction of a diketone-containing amino acid into proteins  Academic Article
• Genomically recoded organisms expand biological functions  Academic Article
• Glutathione S-transferase (transferase pi) from human placenta is identical or closely related to glutathione S-transferase (transferase rho) from erythrocytes  Academic Article
• Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response  Academic Article
• Halofuginone-induced amino acid starvation regulates Stat3-dependent Th17 effector function and reduces established autoimmune inflammation  Academic Article
• Heterocyclic peptide backbone modifications in an α-helical coiled coil  Academic Article
• High affinity targets of protein kinase inhibitors have similar residues at the positions energetically important for binding  Academic Article
• High sensitivity and analyte capture with desorption/ionization mass spectrometry on silylated porous silicon  Academic Article
• High-field c-13 nuclear magnetic-resonance studies at 90.5 mhz of basic pancreatic trypsin-inhibitor  Academic Article
• Highly efficient enantiospecific synthesis of imidazoline-containing amino acids using bis(triphenyl)oxodiphosphonium trifluoromethanesulfonate  Academic Article
• Highly specific oxidative cross-linking of proteins mediated by a nickel-peptide complex  Academic Article
• Human factor XII (Hageman factor)  Academic Article
• Human germline antibody gene segments encode polyspecific antibodies  Academic Article
• Human glomerular basement membrane. Selective solubilization with chaotropes and chemical and immunologic characterization of its components  Academic Article
• Human plasma prekallikrein. Studies of its activation by activated factor XII and of its inactivation by diisopropyl phosphofluoridate  Academic Article
• Human-blood coagulation factor-IX - purification, properties, and mechanism of activation by activated factor-XI  Academic Article
• Hydration and DNA recognition by homeodomains  Academic Article
• Identification and characterization of a type ii peptidyl carrier protein from the bleomycin producer streptomyces verticillus atcc 15003  Academic Article
• Identification of a 13 amino acid peptide mimetic of erythropoietin and description of amino acids critical for the mimetic activity of emp1  Academic Article
• Identification of a cleavage site directing the immunochemical detection of molecular abnormalities in type IIA von Willebrand factor  Academic Article
• Identification of a novel glutathione transferase in human skin homologous with class alpha glutathione transferase 2-2 in the rat  Academic Article
• Identification of a novel integrin binding-site in fibronectin - differential utilization by beta-3 integrins  Academic Article
• Identification of amino acid residues critical for the anti-interferon activity of the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus  Academic Article
• Identification of amino acid residues important for heparan sulfate proteoglycan interaction within variable region 3 of the feline immunodeficiency virus surface glycoprotein  Academic Article
• Identification of amino-acid-residues associated with the 2fe-2s cluster of the 25-kda (nqo2) subunit of the proton-translocating nadh-quinone oxidoreductase of paracoccus-denitrificans  Academic Article
• Identification of metal ion binding peptides containing unnatural amino acids by phage display  Academic Article
• Identification of novel macrocyclic peptidase substrates via on-bead enzymatic cyclization  Academic Article
• Identification of the dicyclohexylcarbodiimide-binding subunit of nadh-ubiquinone oxidoreductase (complex-i)  Academic Article
• Identification of the nadh-binding subunit of energy-transducing nadh-quinone oxidoreductase (ndh-1) of thermus thermophilus hb-8  Academic Article
• Identity of tumor necrosis factor and the macrophage-secreted factor cachectin  Academic Article
• Imidazolopiperazines: Hit to lead optimization of new antimalarial agents  Academic Article
• Immunochemical studies on hen's egg-white lysozyme: Effect of selective nitration of 3 tyrosine residues  Academic Article
• Immunologic and biochemical properties of the histamine-sensitizing factor from Bordetella pertussis  Academic Article
• Importance of single molecular determinants in the fidelity of expanded genetic codes  Academic Article
• Importin beta contains a cooh-terminal nucleoporin binding region important for nuclear transport  Academic Article
• Improved model building and assessment of the Calcium-sensing receptor transmembrane domain  Academic Article
• Improved production of the tallysomycin h-1 in streptoalloteichus hindustanus sb8005 strain by fermentation optimization  Academic Article
• In meso structure of the cobalamin transporter, btub, at 1.95 Å resolution  Academic Article
• In vivo photocrosslinking with unnatural amino acid mutagenesis  Academic Article
• Incorporation of nonnatural amino acids into proteins  Academic Article
• Individual h-1-NMR assignments for the heme groups and the axially bound amino-acids and determination of the coordination geometry at the heme iron in a mixture of 2 isocytochromes-c-551 from rhodopseudomonas-gelatinosa  Academic Article
• Influence of cea-s from different tumors and of cea as i125 ligands on specificity of cea-s radioimmunoassay  Academic Article
• Infrared line shape of an alpha-carbon deuterium-labeled amino acid  Academic Article
• Inhibition of avian-sarcoma virus replication by glucosamine  Academic Article
• Inhibition of lymphocyte protein-synthesis by fibrinogen-derived peptides  Academic Article
• Interaction of urea with an unfolded protein - the DNA-binding domain of the 434-repressor  Academic Article
• Interactions of bovine neurophysins with neurohypophyseal hormones - role of tyrosine-49  Academic Article
• Introduction of cyclically constrained γ-residues stabilizes an α-peptide hairpin in aqueous solution  Academic Article
• Iodopeptides from human thyroglobulin  Academic Article
• Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release?  Academic Article
• Isolation and characterization of a hemagglutinin from limulus polyphemus  Academic Article
• Isolation and characterization of a hemoglobin-derived opioid peptide from the human pituitary-gland  Academic Article
• Isolation and characterization of a mitogen from pokeweed (phytolacca americana)  Academic Article
• Isolation and characterization of ribonucleoprotein substructures from Rous sarcoma virus  Academic Article
• Isolation and characterization of the nd2 polypeptide of the bovine energy-transducing nadh-ubiquinone oxidoreductase (complex i)  Academic Article
• Isolation and chemical characterization of two structurally and functionally distinct forms of botrocetin, the platelet coagglutinin isolated from the venom of Bothrops jararaca  Academic Article
• Isolation and chemical properties of porcine thyrocalcitonin  Academic Article
• Isolation and functional-characterization of the active light chain of activated human-blood coagulation factor-XI  Academic Article
• Isolation and order of the cyanogen bromide fragments of concanavalin a  Academic Article
• Isolation and proteolytic cleavage of the intact subunit of concanavalin a  Academic Article
• Key mechanistic features of enantioselective c-h bond activation reactions catalyzed by (chiral mono-n-protected amino acid)-pd(ii) complexes  Academic Article
• Kinase consensus sequences: A breeding ground for crosstalk  Academic Article
• Kinetic rationalization of nonlinear effects in asymmetric catalysis based on phase behavior  Academic Article
• Ligand-controlled C(sp(3))-H arylation and olefination in synthesis of unnatural chiral alpha-amino acids  Academic Article
• Ligand-enabled cross-coupling of C(sp(3))-H bonds with arylboron reagents via Pd(II)/Pd(0) catalysis  Academic Article
• Ligand-enabled reactivity and selectivity in a synthetically versatile aryl C-H olefination  Academic Article
• Ligand-enabled stereoselective β-C(sp(3))-H fluorination: Synthesis of unnatural enantiopure anti-β-fluoro-α-amino acids  Academic Article
• Ligand-enabled β-C-H arylation of α-amino acids using a simple and practical auxiliary  Academic Article
• Linear and cyclic N-terminal galanin fragments and analogs as ligands at the hypothalamic galanin receptor  Academic Article
• Linear organization of the liver-cell adhesion molecule l-cam  Academic Article
• Localization and characterization of the cleavage-associated neoantigen locus in the e-domain of fibrinogen  Academic Article
• Localization of GroEL determined by in vivo incorporation of a fluorescent amino acid  Academic Article
• Loss of CD4 T-cell-dependent tolerance to proteins with modified amino acids  Academic Article
• Major developmentally regulated protein complex in membranes of dictyostelium  Academic Article
• Making connections: RNA-dependent amino acid recognition  Academic Article
• Many α(IIb)β(3) autoepitopes in chronic immune thrombocytopenic purpura are localized to α(IIb) between amino acids L1 and Q459  Academic Article
• Mapping of 3 carbohydrate attachment sites in embryonic and adult forms of the neural cell-adhesion molecule  Academic Article
• Mechanistic studies of the immunochemical termination of self-tolerance with unnatural amino acids  Academic Article
• Metabolic oxidation regulates embryonic stem cell differentiation  Academic Article
• Metabolic-flux profiling of the yeasts saccharomyces cerevisiae and pichia stipitis  Academic Article
• Metabolomic profiling reveals severe skeletal muscle group-specific perturbations of metabolism in aged FBN rats  Academic Article
• Microtubule stabilization by taxol inhibits initiation of DNA-synthesis by thrombin and by epidermal growth-factor  Academic Article
• Misactivated amino acids translocate at similar rates across surface of a tRNA synthetase  Academic Article
• Mistranslation and its control by tRNA synthetases  Academic Article
• Model of the alpha L beta 2 integrin I-domain/ICAM-1 DI interface suggests that subtle changes in loop orientation determine ligand specificity  Academic Article
• Modeling and functional analysis of the interaction between von Willebrand factor A1 domain and glycoprotein Ib alpha  Academic Article
• Molecular and catalytic properties of glutathione transferase mu from human liver: an enzyme efficiently conjugating epoxides  Academic Article
• Molecular basis for the generation in pigs of influenza a viruses with pandemic potential  Academic Article
• Molecular discrimination of n-protected amino acid esters by a self-assembled cylindrical capsule: Spectroscopic and computational studies  Academic Article
• Molecular mimicry and myasthenia-gravis - an autoantigenic site of the acetylcholine-receptor alpha-subunit that has biologic activity and reacts immunochemically with herpes-simplex virus  Academic Article
• Monitoring the purification by high-performance liquid-chromatography of cardiotoxins from naja-mossambica-mossambica using phase-sensitive two-dimensional nuclear-magnetic-resonance  Academic Article
• Multiple ionic mechanisms are activated by the potent agonist quisqualate in cultured cerebellar Purkinje neurons  Academic Article
• Multiple o-glycoforms on the spore coat protein sp96 in dictyostelium discoideum - fuc(alpha 1-3)glcnac-alpha-1-p-ser is the major modification  Academic Article
• Multiplex assessment of protein variant abundance by massively parallel sequencing  Academic Article
• Multiscale coarse-graining of the protein energy landscape  Academic Article
• Mutagenesis of mouse myeloma cells with Melphalan  Academic Article
• N-H insertion reactions of Boc-amino acid amides: Solution- and solid-phase synthesis of pyrazinones and pyrazines  Academic Article
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• NMR assignment of a human cancer-related nucleoside triphosphatase  Academic Article
• NMR assignment of the spinophilin PDZ domain (493-602)  Academic Article
• NMR studies of structure and function of biological macromolecules (Nobel lecture)  Academic Article
• NMR studies of the conformations of leghemoglobins from soybean and lupin  Academic Article
• Neural cell-adhesion molecules in rodent brains isolated by monoclonal-antibodies with cross-species reactivity  Academic Article
• Neurotransmitter diversity and its functional-significance  Academic Article
• Neutron-scattering studies of the isolated c1r2c1s2 subunit of 1st component of human-complement in solution  Academic Article
• New developments in enzymatic peptide-synthesis  Academic Article
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• Pd(ii)-catalyzed enantioselective activation of c(sp(2))-h and c(sp(3))-h bonds using monoprotected amino acids as chiral ligands  Academic Article
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• Peptide receptor functions on cultured spinal neurons  Academic Article
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• Permissive residues within the minimal epitopes of neutralizing monoclonal antibodies to the v3 loop of hiv-1  Academic Article
• Phage selection for site-specific incorporation of unnatural amino acids into proteins in vivo  Academic Article
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• Pheromone-induced phosphorylation of a g-protein beta-subunit in saccharomyces-cerevisiae is associated with an adaptive response to mating pheromone  Academic Article
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• Photo-crosslinkable unnatural amino acids enable facile synthesis of thermoresponsive nano- to microgels of intrinsically disordered polypeptides  Academic Article
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• Physiologic and pharmacologic considerations of biogenic amines in the nervous system  Academic Article
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• Physiological studies of biosynthetic indole excretion in bacillus alvei  Academic Article
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• Polypeptide chains of immunoglobulins from the smooth dogfish (mustelus canis)  Academic Article
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• Probing protein stability with unnatural amino acids  Academic Article
• Probing protein-protein interactions with a genetically encoded photo-crosslinking amino acid  Academic Article
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• Protein conjugation with genetically encoded unnatural amino acids  Academic Article
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• Recombinant thiopeptides containing noncanonical amino acids  Academic Article
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• Recommendations for the presentation of NMR structures of proteins and nucleic acids. IUPAC-IUBMB-IUPAB Inter-Union Task Group on the Standardization of Data Bases of Protein and Nucleic Acid Structures Determined by NMR Spectroscopy  Academic Article
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• Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival  Academic Article
• Regulation of transcription by unnatural amino acids  Academic Article
• Release factor one is nonessential in Escherichia coli  Academic Article
• Reprogramming the amino-acid substrate specificity of orthogonal aminoacyl-tRNA synthetases to expand the genetic code of eukaryotic cells  Academic Article
• Residue-Specific Peptide Modification: A Chemist's Guide  Academic Article
• Respiratory proteins from the extremely thermophilic aerobic bacterium, thermus-thermophilus - purification procedures for cytochrome-c552, cytochrome-c555,549, and cytochrome-c1aa3 and chemical evidence for a single subunit cytochrome-aa3  Academic Article
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• Reversible photocontrol of biological systems by the incorporation of molecular photoswitches  Academic Article
• Revised amino-acid sequence of qbeta coat protein between positions 1 and 60  Academic Article
• Ribosomal synthesis of macrocyclic peptides in vitro and in vivo mediated by genetically encoded aminothiol unnatural amino acids  Academic Article
• Ribozyme programming extends the protein code  Academic Article
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• Role of N-acyl amino acid ligands in Pd(II)-catalyzed remote C-H activation of tethered arenes  Academic Article
• Role of tRNA orthogonality in an expanded genetic code  Academic Article
• Second-generation DBFOX ligands for the synthesis of β-substituted α-amino acids via enantioselective radical conjugate additions  Academic Article
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• Selective Staudinger modification of proteins containing p-azidophenylalanine  Academic Article
• Selective inhibition of initiator versus executioner caspases using small peptides containing unnatural amino acids  Academic Article
• Selective metabolite and peptide capture/mass detection using fluorous affinity tags  Academic Article
• Selective spin decoupling in the j-resolved 2-dimensional h-1 NMR spectra of proteins  Academic Article
• Self-assembled heterotrimeric collagen triple helices directed through electrostatic interactions  Academic Article
• Self-assembling sequence-adaptive peptide nucleic acids  Academic Article
• Sequence comparison of gamma-crystallins from the reptilian and other vertebrate species  Academic Article
• Sequence position and side chain length dependence of charge pair interactions in collagen triple helices  Academic Article
• Sequence-dependent correction of random coil NMR chemical shifts  Academic Article
• Sequence-specific h-1-NMR assignments and determination of the secondary structure in aqueous-solution of the cardiotoxin-ctxiia and cardiotoxin-ctxiib from naja-mossambica-mossambica  Academic Article
• Sequence-specific resonance assignment of soluble nonglobular proteins by 7D APSY-NMR Spectroscopy  Academic Article
• Sequence-specific resonance assignments in the h-1-NMR spectrum of the lac repressor DNA-binding domain 1-51 from escherichia-coli by two-dimensional spectroscopy  Academic Article
• Side chain NMR assignments in the membrane protein ompx reconstituted in dhpc micelles  Academic Article
• Simple fractionation of phospholipase A2 analogues from snake venom by high-performance liquid chromatography  Academic Article
• Simplification of h-1-NMR spectra of proteins by one-dimensional multiple quantum filtration  Academic Article
• Single amino-acid substitutions in influenza hemagglutinin change receptor-binding specificity  Academic Article
• Single-molecule fluorescence studies of intrinsically disordered proteins  Academic Article
• Site-directed mutagenesis with an expanded genetic code  Academic Article
• Site-selective C(sp3)-H functionalization of di-, tri-, and tetrapeptides at the N-terminus  Academic Article
• Site-specific coupling and sterically controlled formation of multimeric antibody fab fragments with unnatural amino acids  Academic Article
• Site-specific incorporation of novel backbone structures into proteins  Academic Article
• Site-specific labeling of proteins for electron microscopy  Academic Article
• Site-specific labeling of proteins with NMR-active unnatural amino acids  Academic Article
• Site-specific mutagenesis with unnatural amino acids  Academic Article
• Site-specific mutations provide new insights into the origin of pH effects and alternative spectral forms in the photoactive yellow protein from Halorhodospira halophila  Academic Article
• Site-specific pegylation of proteins containing unnatural amino acids  Academic Article
• Solid-phase synthesis and stereochemical assignments of tenuecyclamides A-D employing heterocyclic amino acids derived from commercially available Fmoc alpha-amino acids  Academic Article
• Spectrin redistributes to the cytosol and is phosphorylated during mitosis in cultured cells  Academic Article
• Stability and conformation of a chemoreceptor HAMP domain chimera correlates with signaling properties  Academic Article
• Statistical coupling analysis-guided library design for the discovery of mutant luciferases  Academic Article
• Stereocontrolled synthesis of syn-β-Hydroxy-α-amino acids by direct aldolization of pseudoephenamine glycinamide  Academic Article
• Steroid receptor coactivator peptidomimetics  Academic Article
• Structural and thermodynamic consequences of 1-(4-chlorophenyl)imidazole binding to cytochrome p4502b4  Academic Article
• Structural basis for amplifying vinculin activation by talin  Academic Article
• Structural changes accompanying enzymatic activation of human Hageman factor  Academic Article
• Structural characterization by nuclear magnetic-resonance of a reactive-site carbon-13-labeled basic pancreatic trypsin-inhibitor with the peptide-bond arg-39-ala-40 cleaved and arg-39 removed  Academic Article
• Structural consequences of β-amino acid preorganization in a self-assembling α/β-peptide: fundamental studies of foldameric helix bundles  Academic Article
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• Substituting c-jun n-terminal kinase-3 (jnk3) atp-binding site amino acid residues with their p38 counterparts affects binding of jnk- and p38-selective inhibitors  Academic Article
• Substrate recognition and selection by the initiation module PheATE of gramicidin S synthetase  Academic Article
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• Subunit structure of glyoxalase I from yeast  Academic Article
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• Symmetrical stabilization of bound Ca2+ ions in a cooperative pair of EF-hands through hydrogen bonding of coordinating water molecules in calbindin D-9k  Academic Article
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• Synthesis and coupling reactions of alpha,alpha-dialkylated amino acids with nucleobase side chains  Academic Article
• Synthesis and novel structure-activity relationships of potent sansalvamide A derivatives  Academic Article
• Synthesis and self-assembly of NCN-pincer Pd-complex-bound norvalines  Academic Article
• Synthesis of Sansalvamide A derivatives and their cytotoxicity in the MSS colon cancer cell line HT-29  Academic Article
• Synthesis of all nineteen appropriately protected chiral alpha-hydroxy acid equivalents of the alpha-amino acids for Boc solid-phase depsi-peptide synthesis  Academic Article
• Synthesis of bispecific antibodies using genetically encoded unnatural amino acids  Academic Article
• Synthesis of cyclic and acyclic β-amino acids via chelation-controlled 1,3-dipolar cycloaddition  Academic Article
• Synthesis of novel 6-amido-6-deoxy-l-galactose derivatives as sialyl lewis x mimetics  Academic Article
• Synthesis of second-generation Sansalvamide A derivatives: novel templates as potential antitumor agents  Academic Article
• Synthesis of site-specific antibody-drug conjugates using unnatural amino acids  Academic Article
• Synthesis of sulfotyrosine-containing peptides by incorporating fluorosulfated tyrosine using an Fmoc-based solid-phase strategy  Academic Article
• Synthesis of the chlorofusin cyclic peptide: assignment of the asparagine stereochemistry  Academic Article
• Synthesis of β-substituted α-amino acids via Lewis acid promoted enantioselective radical conjugate additions  Academic Article
• Synthesis of β-substituted α-amino acids via Lewis acid promoted radical conjugate additions to α,β-unsaturated α-nitro esters and amides  Academic Article
• Synthetase polyspecificity as a tool to modulate protein function  Academic Article
• Systematic application of high-resolution, phase-sensitive two-dimensional h-1-NMR techniques for the identification of the amino-acid-proton spin systems in proteins - rabbit metallothionein-2  Academic Article
• Systematic application of two-dimensional h-1-NMR techniques for studies of proteins .1. Combined use of spin-echo-correlated spectroscopy and j-resolved spectroscopy for the identification of complete spin systems of non-labile protons in amino-acid-residues  Academic Article
• Systematic application of two-dimensional h-1-NMR techniques for studies of proteins .2. Combined use of correlated spectroscopy and nuclear overhauser spectroscopy for sequential assignments of backbone resonances and elucidation of polypeptide secondary structures  Academic Article
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• The polymorphic human glutathione transferase T1-1, the most efficient glutathione transferase in the denitrosation and inactivation of the anticancer drug 1,3-bis(2-chloroethyl)-1-nitro sourea  Academic Article
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• Thiol ligation of two zinc atoms to a class I tRNA synthetase: evidence for unshared thiols and role in amino acid binding and utilization  Academic Article
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