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• A chloroacetamidine-based inactivator of protein arginine methyltransferase 1: Design, synthesis, and in vitro and in vivo evaluation  Academic Article
• A fluoroacetamidine-based inactivator of protein arginine deiminase 4: Design, synthesis, and in vitro and in vivo evaluation  Academic Article
• Amidines as amide bond replacements in VLA-4 antagonists  Academic Article
• Biophysical and transfection studies of the dic(14)-amidine/DNA complex  Academic Article
• Characterization and inactivation of an agmatine deiminase from helicobacter pylori  Academic Article
• Cyclic amidine sugars as transition-state analogue inhibitors of glycosidases: Potent competitive inhibitors of mannosidases  Academic Article
• Cycloadditions of 1,2,3-triazines bearing C5-electron donating substituents: robust pyrimidine synthesis  Academic Article
• Development and use of clickable activity based protein profiling agents for protein arginine deiminase 4  Academic Article
• Discovery of a series of efficient, centrally efficacious BACE1 inhibitors through structure-based drug design  Academic Article
• Discovery of potent competitive inhibitors of indoleamine 2,3-dioxygenase with in vivo pharmacodynamic activity and efficacy in a mouse melanoma model  Academic Article
• First practical synthesis of formamidine ureas and derivatives  Academic Article
• Haloacetamidine-based inactivators of protein arginine deiminase 4 (pad4): Evidence that general acid catalysis promotes efficient inactivation  Academic Article
• Hydroxyamidine inhibitors of indoleamine-2,3-dioxygenase potently suppress systemic tryptophan catabolism and the growth of IDO-expressing tumors  Academic Article
• Inhibitors and inactivators of protein arginine deiminase 4: Functional and structural characterization  Academic Article
• Modelling of Factor Xa-inhibitor complexes: a computational flexible docking approach  Academic Article
• N-alpha-benzoyl-n5-(2-chloro-1-iminoethyl)-l-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis  Academic Article
• Organocatalytic, diastereo- and enantioselective synthesis of nonsymmetric cis-stilbene diamines: a platform for the preparation of single-enantiomer cis-imidazolines for protein-protein inhibition  Academic Article
• Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice  Academic Article
• Protein arginine deiminase 4: A target for an epigenetic cancer therapy  Academic Article
• Rhodium(II)-catalyzed asymmetric sulfur(VI) reduction of diazo sulfonylamidines  Academic Article
• Silver(I)-promoted conversion of thioamides to amidines: divergent synthesis of a key series of vancomycin aglycon residue 4 amidines that clarify binding behavior to model ligands  Academic Article
• Synthesis and screening of a haloacetamidine containing library to identify PAD4 selective inhibitors  Academic Article
• Synthesis and use of a phosphonate amidine to generate an anti-phosphoarginine-specific antibody  Academic Article
• The development of n-alpha-(2-carboxyl)benzoyl-n(5)-(2-fluoro-1-iminoethyl)-l-ornithine amide (o-f-amidine) and n-alpha-(2-carboxyl)benzoyl-n(5)-(2-chloro-1-iminoethyl)-l-ornithine amide (o-cl-amidine) as second generation protein arginine deiminase (pad) inhibitors  Academic Article
• The induction of microrna-16 in colon cancer cells by protein arginine deiminase inhibition causes a p53-dependent cell cycle arrest  Academic Article
• Total syntheses of (-)-pyrimidoblamic acid and P-3A  Academic Article