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Aging

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  • 1B1075: a brain- and pituitary-specific mRNA that encodes a novel chromogranin/secretogranin-like component of intracellular vesicles  Academic Article
  • A comprehensive analysis of replicative lifespan in 4,698 Single-gene deletion strains uncovers conserved mechanisms of aging  Academic Article
  • A developmental influence of the N-methyl-D-aspartate receptor NR3A subunit on prepulse inhibition of startle  Academic Article
  • A mouse model of accelerated liver aging caused by a defect in DNA repair  Academic Article
  • A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis  Academic Article
  • A proinflammatory mediator with potential relevance in aging  Academic Article
  • A prospective epigenetic paradigm between cellular senescence and epithelial-mesenchymal transition in organismal development and aging  Academic Article
  • A role for alstrom syndrome protein, alms1, in kidney ciliogenesis and cellular quiescence  Academic Article
  • A role for stem cell biology in the physiological and pathological aspects of aging  Academic Article
  • A spontaneous rheumatoid arthritis-like disease in mrl/1 mice  Academic Article
  • Aberrant autolysosomal regulation is linked to the induction of embryonic senescence: differential roles of Beclin 1 and p53 in vertebrate Spns1 deficiency  Academic Article
  • Aberrant wound healing and tgf-beta production in the autoimmune-prone mrl/+ mouse  Academic Article
  • Abeta localization in abnormal endosomes: Association with earliest Abeta elevations in AD and down syndrome  Academic Article
  • Accelerated aging of intervertebral discs in a mouse model of progeria  Academic Article
  • Accelerated, aging-dependent development of osteoarthritis in alpha 1 integrin-deficient mice  Academic Article
  • Activated Protein C Strengthens Cardiac Tolerance to Ischemic Insults in Aging  Academic Article
  • Adapting proteostasis for disease intervention  Academic Article
  • Adoptive transfer of neonatal T lymphocytes rescues immunoglobulin production in mice with severe combined immune deficiency  Academic Article
  • Adult CST-null mice maintain an increased number of oligodendrocytes  Academic Article
  • Adult mice generated from induced pluripotent stem cells  Academic Article
  • Adult neurogenesis: Can analysis of cell cycle proteins move us "Beyond BrdU"?  Academic Article
  • Age and outcome with contemporary thrombolytic therapy - results from the gusto-i trial  Academic Article
  • Age, physical fitness, and attention: P3a and p3b  Academic Article
  • Age- and gender-specific changes of hypocretin immunopositive neurons in C57Bl/6 mice  Academic Article
  • Age- and site-associated biomechanical weakening of human articular cartilage of the femoral condyle  Academic Article
  • Age-associated bidirectional modulation of gene expression in single identified R15 neuron of Aplysia  Academic Article
  • Age-dependent inverse correlations in CSF and plasma amyloid-β(1-42) concentrations prior to amyloid plaque deposition in the brain of 3xTg-AD mice  Academic Article
  • Age-dependent regulation of tendon crimp structure, cell length and gap width with strain  Academic Article
  • Age-independent and age-related deficits in visuospatial learning, sleep-wake states, thermoregulation and motor activity in PDAPP mice  Academic Article
  • Age-related differences in the blood alcohol levels of wistar rats  Academic Article
  • Age-related effects of Ginkgo biloba extract on synaptic plasticity and excitability  Academic Article
  • Age-related impairments of synaptic plasticity in the lateral perforant path input to the dentate gyrus of galanin overexpressing mice  Academic Article
  • Age-related oxidative modifications of transthyretin modulate its amyloidogenicity  Academic Article
  • Age-related thymic activity in adults following chemotherapy-induced lymphopenia  Academic Article
  • Aged app23 mice show a delay in switching to the use of a strategy in the barnes maze  Academic Article
  • Aging accelerates endotoxin-induced thrombosis: increased responses of plasminogen activator inhibitor-1 and lipopolysaccharide signaling with aging  Academic Article
  • Aging and chronic virus-infection - is there a relationship  Academic Article
  • Aging and obesity augment the stress-induced expression of tissue factor gene in the mouse  Academic Article
  • Aging impairs intermediate-term behavioral memory by disrupting the dorsal paired medial neuron memory trace  Academic Article
  • Aging impairs protein-synthesis-dependent long-term memory in Drosophila  Academic Article
  • Aging leads to a programmed loss of brown adipocytes in murine subcutaneous white adipose tissue  Academic Article
  • Aging leads to disturbed homeostasis of memory phenotype cd8(+) cells  Academic Article
  • Aging of the circadian system in zebrafish and the effects of melatonin on sleep and cognitive performance  Academic Article
  • Aging-related concerns and body-image - possible future implications for eating disorders  Academic Article
  • Aging-related differences in chondrocyte viscoelastic properties  Academic Article
  • Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis  Academic Article
  • Alteration of the retinotectal map in xenopus by antibodies to neural cell-adhesion molecules  Academic Article
  • Altered DNA methylation in leukocytes with trisomy 21  Academic Article
  • Amyloid and nonfibrillar deposits in mice transgenic for wild-type human transthyretin: A possible model for senile systemic amyloidosis  Academic Article
  • Amyloidogenesis is neither accelerated nor enhanced by injections of preformed fibrils in mice transgenic for wild-type human transthyretin: The question of infectivity  Academic Article
  • An aged immune system drives senescence and ageing of solid organs  Academic Article
  • An antidepressant that extends lifespan in adult caenorhabditis elegans  Academic Article
  • An automated high-throughput assay for survival of the nematode Caenorhabditis elegans  Academic Article
  • An essential role for Rxr alpha in the development of Th2 responses  Academic Article
  • An overview of the results of the EPIC trial  Academic Article
  • An overview of underlying causes and animal models for the study of age-related degenerative disorders of the spine and synovial joints  Academic Article
  • Aneuploid mosaicism in the developing and adult cerebellar cortex  Academic Article
  • Anterior cruciate ligament changes in the human knee joint in aging and osteoarthritis  Academic Article
  • Apolipoprotein d mrna expression is elevated in pdapp transgenic mice  Academic Article
  • Appetitive motivational experience during adolescence results in enhanced alcohol consumption during adulthood  Academic Article
  • Atomic force microscopy reveals age-dependent changes in nanomechanical properties of the extracellular matrix of native human menisci: implications for joint degeneration and osteoarthritis  Academic Article
  • Atypical BSE (BASE) transmitted from asymptomatic aging cattle to a primate  Academic Article
  • Atypical antidepressants extend lifespan of Caenorhabditis elegans by activation of a non-cell-autonomous stress response  Academic Article
  • Autophagy and cartilage homeostasis mechanisms in joint health, aging and OA  Academic Article
  • Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis  Academic Article
  • Behavioral and neurochemical studies on brain aging in galanin overexpressing mice  Academic Article
  • Behavioral and transcriptome alterations in male and female mice with postnatal deletion of TrkB in dorsal striatal medium spiny neurons  Academic Article
  • Biochemical and morphological-changes in the developing kidney  Academic Article
  • Blue journal conference. Aging and susceptibility to lung disease  Academic Article
  • Blunted neurogenesis and gliosis due to transgenic overexpression of human soluble IL-1ra in the mouse  Academic Article
  • Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor  Academic Article
  • Candidate SNP associations of optimism and resilience in older adults: exploratory study of 935 community-dwelling adults  Academic Article
  • Caspase inhibition in select olfactory neurons restores innate attraction behavior in aged Drosophila  Academic Article
  • Caspase remodeling of the spectrin membrane skeleton during lens development and aging  Academic Article
  • Cd36 is a sensor of diacylglycerides  Academic Article
  • Cell proliferation and cytokine production by CD4+ cells from old mice  Academic Article
  • Cell-specific effects of thyroid hormone on rc3/neurogranin expression in rat brain  Academic Article
  • Cellular and extracellular matrix changes in anterior cruciate ligaments during human knee aging and osteoarthritis  Academic Article
  • Cellular and subcellular-localization of muscarinic acetylcholine-receptors during postnatal-development of cat visual-cortex using immunocytochemical procedures  Academic Article
  • Cellular-distribution and expression of cortical acetylcholine-receptors in aging and alzheimers-disease  Academic Article
  • Chemotaxis of human articular chondrocytes and mesenchymal stem cells  Academic Article
  • Clinical neurophysiology of aging brain: From normal aging to neurodegeneration  Academic Article
  • Cloning a novel form of rat pdgf a-chain with a unique 5'-ut - regulation during development and in glomerulonephritis  Academic Article
  • Co-expression of VAL- and TMT-opsins uncovers ancient photosensory interneurons and motorneurons in the vertebrate brain  Academic Article
  • Coexpression network analysis of neural tissue reveals perturbations in developmental processes in schizophrenia  Academic Article
  • Cognitive aging in zebrafish  Academic Article
  • Cohort profile: the Swiss HIV Cohort study  Academic Article
  • Colocalization of muscarinic and nicotinic receptors in cholinoceptive neurons of the suprachiasmatic region in young and aged rats  Academic Article
  • Comparative proteomic analysis of the aging soleus and extensor digitorum longus rat muscles using TMT labeling and mass spectrometry  Academic Article
  • Considerations on temperature, longevity and aging  Academic Article
  • Contemporary human genetic strategies in aging research  Academic Article
  • Contribution of glutamatergic signaling to nitrosative stress-induced protein misfolding in normal brain aging and neurodegenerative diseases  Academic Article
  • Cortistatin overexpression in transgenic mice produces deficits in synaptic plasticity and learning  Academic Article
  • Coxsackievirus b3 and the neonatal cns - the roles of stem cells, developing neurons, and apoptosis in infection, viral dissemination, and disease  Academic Article
  • Critical periods for experience-dependent synaptic scaling in visual cortex  Academic Article
  • Cure of prediabetic mice by viral infections involves lymphocyte recruitment along an IP-10 gradient  Academic Article
  • Cyclin D3 maintains growth-inhibitory activity of C/EBPalpha by stabilizing C/EBPalpha-cdk2 and C/EBPalpha-Brm complexes  Academic Article
  • Cytotactin and cytotactin-binding proteoglycan. An interactive pair of extracellular matrix proteins  Academic Article
  • DNA repair is crucial for maintaining hematopoietic stem cell function  Academic Article
  • Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression, and apoptosis in mice lacking fatty acid amide hydrolase  Academic Article
  • Deep-brain magnetic stimulation promotes adult hippocampal neurogenesis and alleviates stress-related behaviors in mouse models for neuropsychiatric disorders  Academic Article
  • Deficient ghrelin receptor-mediated signaling compromises thymic stromal cell microenvironment by accelerating thymic adiposity  Academic Article
  • Deficits in discriminated learning remain despite clearance of long-term persistent viral infection in mice  Academic Article
  • Depletion of fat-resident T-reg cells prevents age-associated insulin resistance  Academic Article
  • Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland  Academic Article
  • Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease  Academic Article
  • Developing master keys to brain pathology, cancer and aging from the structural biology of proteins controlling reactive oxygen species and DNA repair  Academic Article
  • Development and regulation of beta-adrenergic receptors in kitten visual-cortex - an immunocytochemical and autoradiographic study  Academic Article
  • Developmental and regional expression pattern of a novel NMDA receptor-like subunit (NMDAR-L) in the rodent brain  Academic Article
  • Developmental changes in Ca2+-regulated functions of early postnatal Purkinje neurons  Academic Article
  • Developmental differences in EEG and sleep responses to acute ethanol administration and its withdrawal (hangover) in adolescent and adult Wistar rats  Academic Article
  • Developmental effects of wheel running on hippocampal glutamate receptor expression in young and mature adult rats  Academic Article
  • Developmental regulation of beta 1 integrins during angiogenesis in the central nervous system  Academic Article
  • Diabetes accelerates retinal ganglion cell dysfunction in mice lacking sigma receptor 1  Academic Article
  • Differences in the degree of depletion, rate of recovery, and the preferential elimination of naive cd4(+) t-cells by anti-cd4 monoclonal-antibody (gk1.5) in young and aged mice  Academic Article
  • Differences in the expression profiles of CD45RB, Pgp-1, and 3G11 membrane antigens and in the patterns of lymphokine secretion by splenic CD4+ T cells from young and aged mice  Academic Article
  • Differential age- and disease-related effects on the expression of genes related to the arachidonic acid signaling pathway in schizophrenia  Academic Article
  • Differential effects of acute alcohol on EEG and sedative responses in adolescent and adult Wistar rats  Academic Article
  • Differential effects of aging on human chondrocyte responses to transforming growth factor beta - increased pyrophosphate production and decreased cell proliferation  Academic Article
  • Differential effects of genotoxic stress on both concurrent body growth and gradual senescence in the adult zebrafish  Academic Article
  • Discovery of a proneurogenic, neuroprotective chemical  Academic Article
  • Disease- and age-related changes in histone acetylation at gene promoters in psychiatric disorders  Academic Article
  • Disruption of α3 connexin gene leads to proteolysis and cataractogenesis in mice  Academic Article
  • Distinct shifts in microbiota composition during Drosophila aging impair intestinal function and drive mortality  Academic Article
  • Distinct synaptic and extrasynaptic NMDA receptors in developing cerebellar granule neurons  Academic Article
  • Distribution of lymphocytes identified by surface markers in murine strains with systemic lupus erythematosus-like syndromes  Academic Article
  • Divide and conquer: Nucleotide excision repair battles cancer and ageing  Academic Article
  • Downregulation of the tyrosine degradation pathway extends Drosophila lifespan  Academic Article
  • Dysregulated FOXO transcription factors in articular cartilage in aging and osteoarthritis  Academic Article
  • Early-onset behavioral and synaptic deficits in a mouse model of alzheimer's disease  Academic Article
  • Effect of age on outcome with primary angioplasty versus thrombolysis  Academic Article
  • Effects of age on delta and REM-sleep parameters  Academic Article
  • Effects of age on the p300 component of the event-related potential from auditory-stimuli - peak definition, variation, and measurement  Academic Article
  • Effects of aging on articular cartilage homeostasis  Academic Article
  • Effects of ketanserin on blood pressure and platelet aggregation in elderly men with mild hypertension  Academic Article
  • Efficient peripheral clonal elimination of b lymphocytes in mrl/lpr mice bearing autoantibody transgenes  Academic Article
  • Electrophysiological and cerebrovascular effects of the α-secretase-derived form of amyloid precursor protein in young and middle-aged rats  Academic Article
  • Elevations of hepatic quinone reductase, glutathione, and α- and μ-class glutathione S-transferase isoforms in mice with chronic hepatitis: a compensatory response to injury  Academic Article
  • Embryonic senescence and laminopathies in a progeroid zebrafish model  Academic Article
  • Embryonic to adult conversion of neural cell-adhesion molecules in normal and staggerer mice  Academic Article
  • Endocrine targets for pharmacological intervention in aging in Caenorhabditis elegans  Academic Article
  • Enhanced allostimulatory activity of host antigen-presenting cells in old mice intensifies acute graft-versus-host disease  Academic Article
  • Enhanced prepulse inhibition following adolescent ethanol exposure in Sprague-Dawley rats  Academic Article
  • Erythropoietin, gdf15, il6, hepcidin and testosterone levels in a large cohort of elderly individuals with anaemia of known and unknown cause  Academic Article
  • Event-related potential responses to the acute and chronic effects of alcohol in adolescent and adult Wistar rats  Academic Article
  • Expression of the yeast nadh dehydrogenase ndi1 in drosophila confers increased lifespan independently of dietary restriction  Academic Article
  • Extension of life-span with superoxide dismutase/catalase mimetics  Academic Article
  • Factors associated with remission from alcohol dependence in an American Indian community group  Academic Article
  • Ferroportin 1 (SCL40A1) variant associated with iron overload in African-Americans  Academic Article
  • Fmr1 deficiency promotes age-dependent alterations in the cortical synaptic proteome  Academic Article
  • Functional aging and gradual senescence in zebrafish  Academic Article
  • G1 arrest and high expression of cyclin kinase and apoptosis inhibitors in accumulated activated memory phenotype CD4(+) cells of older lupus mice  Academic Article
  • Gene organization and chromosome location of the neural-specific rna binding protein elavl4  Academic Article
  • Generation and phenotypic characterization of a galanin overexpressing mouse  Academic Article
  • Genesis and evolution of antichromatin autoantibodies in murine lupus implicates t-dependent immunization with self antigen  Academic Article
  • Genetic and regulatory contributions of the major histocompatibility complex to the developing cytolytic T lymphocyte repertoire  Academic Article
  • Genetic approaches to memory storage  Academic Article
  • Genetic deletion of NR3A accelerates glutamatergic synapse maturation  Academic Article
  • Genetic studies in systemic autoimmunity and aging  Academic Article
  • Ghrelin and growth hormone secretagogue receptor expression in mice during aging  Academic Article
  • Ghrelin promotes thymopoiesis during aging  Academic Article
  • Ghrelin receptor (GHS-R1A) agonists show potential as interventive agents during aging  Academic Article
  • Growth hormone corrects proliferation and transcription of phosphoenolpyruvate carboxykinase in livers of old mice via elimination of CCAAT/enhancer-binding protein alpha-Brm complex  Academic Article
  • Growth hormone secretagogues modulate the electrical and contractile properties of rat skeletal muscle through a ghrelin-specific receptor  Academic Article
  • Growth-factor responsiveness of human articular chondrocytes in aging and development  Academic Article
  • HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells  Academic Article
  • Haemoglobin and ferritin concentrations in men and women: Cross sectional study  Academic Article
  • Hematocrit levels and physiological factors in relationship to cardiovascular risk in tecumseh, michigan  Academic Article
  • Histopathological changes in the human posterior cruciate ligament during aging and osteoarthritis: Correlations with anterior cruciate ligament and cartilage changes  Academic Article
  • How a mutation that slows aging can Also disproportionately extend end-of-life decrepitude  Academic Article
  • Huffington Center on Aging  Academic Article
  • Hyaluronan concentration and size distribution in human knee synovial fluid: variations with age and cartilage degeneration  Academic Article
  • IL-1/IL-1ra balance in the brain revisited - Evidence from transgenic mouse models  Academic Article
  • IL-6 mediated degeneration of forebrain GABAergic interneurons and cognitive impairment in aged mice through activation of neuronal NADPH oxidase  Academic Article
  • Identification of a b-cell differentiation factor(s) spontaneously produced by proliferating t-cells in murine lupus strains of the lpr-lpr genotype  Academic Article
  • Identification of the form of cytochrome P-450 induced in neonatal rabbit liver microsomes by phenobarbital  Academic Article
  • IgG subclasses of anti-tetanus toxoid antibodies in adult and newborn normal subjects and in patients with systemic lupus erythematosus, Sjögren's syndrome, and drug-induced autoimmunity  Academic Article
  • Immunohistochemical analysis of the development of somatostatin in the reeler neocortex  Academic Article
  • Impaired genome maintenance suppresses the growth hormone-insulin-like growth factor 1 axis in mice with cockayne syndrome  Academic Article
  • In vitro model of full-thickness cartilage defect healing  Academic Article
  • In vivo and in vitro production of anti-histone antibodies in NZB/NZW mice  Academic Article
  • Inactivation of JAK2/STAT3 Signaling Axis and Downregulation of M1 mAChR Cause Cognitive Impairment in klotho Mutant Mice, a Genetic Model of Aging  Academic Article
  • Increased anxiety-like behavior in adult rats exposed to nicotine as adolescents  Academic Article
  • Increased exon 5 expression alters extrasynaptic NMDA receptors in cerebellar neurons  Academic Article
  • Increased expression of plasminogen activator inhibitor-1 with fibrin deposition in a murine model of aging, "klotho" mouse  Academic Article
  • Increased insulin sensitivity and diminished pancreatic beta-cell function in DNA repair deficient Ercc1(d/-) mice  Academic Article
  • Increased spectrin proteolysis in fibroblasts from aged and alzheimer donors  Academic Article
  • Increased spectrin proteolysis in the brindled mouse-brain  Academic Article
  • Increasing t-cell age reduces effector activity but preserves proliferative capacity in a murine allogeneic major histocompatibility complex - mismatched bone marrow transplant model  Academic Article
  • Individual differences in cognitive aging: implication of pregnenolone sulfate  Academic Article
  • Infectious diseases society of america guidelines for the diagnosis and treatment of asymptomatic bacteriuria in adults  Academic Article
  • Inositol pyrophosphates inhibit Akt signaling, thereby regulating insulin sensitivity and weight gain  Academic Article
  • Interactive effects of common beta(2)-adrenoceptor haplotypes and age on susceptibility to hypertension and receptor function  Academic Article
  • Is older colder or colder older? The association of age with body temperature in 18,630 individuals  Academic Article
  • Isotypic profiles and other fine characteristics of immune-responses to exogenous thymus-dependent and thymus-independent antigens by mice with lupus syndromes  Academic Article
  • Issls prize winner: Inhibition of nf-kappa b activity ameliorates age-associated disc degeneration in a mouse model of accelerated aging  Academic Article
  • Lack of correlation between the spatial distribution of A2E and lipofuscin fluorescence in the human retinal pigment epithelium  Academic Article
  • Leptin binding activity changes with age: The link between leptin and puberty  Academic Article
  • Leptin measurement in urine in children and its relationship to other growth peptides in serum and urine  Academic Article
  • Leu5enkephalin-encoding sequences are targets for a specific DNA-binding factor.  Academic Article
  • Low brain allopregnanolone levels mediate flattened circadian activity associated with memory impairments in aged rats  Academic Article
  • Low circulating adropin concentrations with obesity and aging correlate with risk factors for metabolic disease and increase after gastric bypass surgery in humans  Academic Article
  • Macrophage i-a/i-e expression and macrophage-stimulating lymphokines in murine lupus  Academic Article
  • Macroscopic and histopathologic analysis of human knee menisci in aging and osteoarthritis  Academic Article
  • Male determined accelerated autoimmune-disease in bxsb mice - transfer by bone-marrow and spleen-cells  Academic Article
  • Malfolded protein structure and proteostasis in lung diseases  Academic Article
  • Mapping of 3 carbohydrate attachment sites in embryonic and adult forms of the neural cell-adhesion molecule  Academic Article
  • Maternal adaptive immunity influences the intestinal microflora of suckling mice  Academic Article
  • Mediation of spontaneous knee osteoarthritis by progressive chondrocyte ATP depletion in Hartley guinea pigs  Academic Article
  • Meta-analysis of p300 normative aging studies  Academic Article
  • Metabolomic profiling reveals severe skeletal muscle group-specific perturbations of metabolism in aged FBN rats  Academic Article
  • MicroRNA profiling reveals age-dependent differential expression of nuclear factor kappa B and mitogen-activated protein kinase in adipose and bone marrow-derived human mesenchymal stem cells  Academic Article
  • Microbes without borders: decompartmentalization of the aging gut  Academic Article
  • Milk consumption during adolescence decreases alcohol drinking in adulthood  Academic Article
  • Mir-290-295 deficiency in mice results in partially penetrant embryonic lethality and germ cell defects  Academic Article
  • Mitochondrial fission in apoptosis, neurodegeneration and aging  Academic Article
  • Mitotic misregulation and human aging  Academic Article
  • Molecular and chemical genetic approaches to developmental origins of aging and disease in zebrafish  Academic Article
  • Molecular cloning and functional characterization of zebrafish ATM  Academic Article
  • Molecular endocrinology and physiology of the aging central nervous system  Academic Article
  • Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice  Academic Article
  • Molecular pathway to protection from age-dependent photoreceptor degeneration in Mef2 deficiency  Academic Article
  • Morphology and distribution of neurons and glial-cells expressing beta-adrenergic receptors in developing kitten visual-cortex  Academic Article
  • Murine mesenchymal stem cells transplanted to the central nervous system of neonatal versus adult mice exhibit distinct engraftment kinetics and express receptors that guide neuronal cell migration  Academic Article
  • Muscarinic acetylcholine receptor-expression in astrocytes in the cortex of young and aged rats  Academic Article
  • Myosin transducer mutations differentially affect motor function, myofibril structure, and the performance of skeletal and cardiac muscles  Academic Article
  • N-glycosylation is essential for vesicular targeting of synaptotagmin 1  Academic Article
  • NF-kB inhibition delays DNA damage-induced senescence and aging in mice  Academic Article
  • Natural thymocytotoxic autoantibodies in auto-immune and normal mice  Academic Article
  • Negative selection in vivo reveals expression of strong Mls determinants in mice with X-linked immunodeficiency  Academic Article
  • Neural cell-adhesion molecules in rodent brains isolated by monoclonal-antibodies with cross-species reactivity  Academic Article
  • Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1  Academic Article
  • Neuroactive steroids: New biomarkers of cognitive aging  Academic Article
  • Neuroanatomical assessment of biological maturity  Academic Article
  • Neurosteroids and cholinergic systems: implications for sleep and cognitive processes and potential role of age-related changes  Academic Article
  • New insights into the role of neuroactive steroids in cognitive aging  Academic Article
  • Night eating and obesity in the EP3R-deficient mouse  Academic Article
  • Noninvasive trigeminal evoked-potentials - normative aging data  Academic Article
  • Normal aging and odor intensity effects on the olfactory event-related potential  Academic Article
  • Normal development and behavior of mice lacking the neuronal cell-surface prp protein  Academic Article
  • Normal human aging and early-stage schizophrenia share common molecular profiles  Academic Article
  • Normal variation of p300 in children - age, memory span, and head size  Academic Article
  • Numerical chromosome variation and mitotic segregation defects in the adult brain of teleost fish  Academic Article
  • Obesity accelerates thymic aging  Academic Article
  • Olfactory event-related potentials and aging: Normative data  Academic Article
  • Olfactory p3 in young and older adults  Academic Article
  • Olfactory-evoked potentials - assessment of young and elderly, and comparison to psychophysical threshold  Academic Article
  • On the relationship between eec and p300: Individual differences, aging, and ultradian rhythms  Academic Article
  • Ontogeny of T cell tolerance to peripherally expressed antigens  Academic Article
  • Opioid peptides and alpha-melanocyte-stimulating hormone in genetically-obese (ob-ob) mice during development  Academic Article
  • Opposing activities protect against age-onset proteotoxicity  Academic Article
  • Organ-specific and age-specific replication of polyomavirus in mice  Academic Article
  • Oxidative stress and aging - the use of superoxide dismutase/catalase mimetics to extend lifespan  Academic Article
  • Oxime-assisted acetylcholinesterase catalytic scavengers of organophosphates that resist aging  Academic Article
  • P300 clinical utility and control of variability  Academic Article
  • P300 in the evaluation of aging and dementia  Academic Article
  • P300 in young and elderly subjects - auditory frequency and intensity effects  Academic Article
  • P300 latency reflects the degree of cognitive decline in dementing illness  Academic Article
  • Paranodal reorganization results in the depletion of transverse bands in the aged central nervous system  Academic Article
  • Patterns of cytokine gene expression by CD4+ T cells from young and old mice  Academic Article
  • Periadolescent alcohol exposure has lasting effects on adult neurophysiological function in rats  Academic Article
  • Peroxisome proliferator-activated receptor gamma coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator in muscle 1 (Perm1) is a tissue-specific regulator of oxidative capacity in skeletal muscle cells  Academic Article
  • Peroxisome proliferator-activated receptor γ coactivator 1α and FoxO3A mediate chondroprotection by AMP-activated protein kinase  Academic Article
  • Persistent degenerative changes in thymic organ function revealed by an inducible model of organ regrowth  Academic Article
  • Physiological T-cell death: susceptibility is modulated by activation, aging, and transformation, but the mechanism is constant  Academic Article
  • Plasminogen activator inhibitor-1 is a major stress-regulated gene: Implications for stress-induced thrombosis in aged individuals  Academic Article
  • Polymerase chain-reaction cloning of a developmentally-regulated member of the sialyltransferase gene family  Academic Article
  • Population structure, admixture, and aging-related phenotypes in african american adults: The cardiovascular health study  Academic Article
  • Positive modulation of ampa receptors increases neurotrophin expression by hippocampal and cortical neurons  Academic Article
  • Potential and current use of N-methyl-D-aspartate (NMDA) receptor antagonists in diseases of aging  Academic Article
  • Premature aging-related peripheral neuropathy in a mouse model of progeria  Academic Article
  • Programmed cell death is a universal feature of embryonic and postnatal neuroproliferative regions throughout the central nervous system  Academic Article
  • Propensity of adult lymphoid progenitors to progress to DN2/3 stage thymocytes with notch receptor ligation  Academic Article
  • Quantitative analysis of age specific variation in the abundance of human female parotid salivary proteins  Academic Article
  • Quantitative mass spectrometry identifies insulin signaling targets in C. elegans  Academic Article
  • RGS9: a regulator of G-protein signalling with specific expression in rat and mouse striatum  Academic Article
  • Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome  Academic Article
  • Red-blood-cell lithium-sodium countertransport in the tecumseh blood-pressure study  Academic Article
  • Redistribution of synaptic vesicle antigens is correlated with the disappearance of a transient synaptic zone in the developing cerebral cortex  Academic Article
  • Region-specific changes in the microanatomy of single dendritic spines over time might account for selective memory alterations in ageing hAPPsweTg2576 mice, a mouse model for Alzheimer disease  Academic Article
  • Regional and age-dependent differences in the affinity of dopamine d-2 agonist binding in the rat-brain  Academic Article
  • Regulation of neuroblast cell-cycle kinetics plays a crucial role in the generation of unique features of neocortical areas  Academic Article
  • Regulation of neuronal oxytocin messenger-rna by ovarian-steroids in the mature and developing hypothalamus  Academic Article
  • Regulation of the rabbit cytochrome-P-450 3C gene - age-dependent expression and transcriptional activation by rifampicin  Academic Article
  • Relationship of age and sex to autoantibody expression in MRL-+/+ and MRL-lpr/lpr mice: demonstration of an association between the expression of antibodies to histones, denatured DNA and Sm in MRL-+/+ mice  Academic Article
  • Relationship of growth and blood-pressure in inbred rats  Academic Article
  • Relative abundance of alzheimer a-beta amyloid peptide variants in alzheimer-disease and normal aging  Academic Article
  • Renal expression of fibrinolytic genes and tissue factor in a murine model of renal disease as a function of age  Academic Article
  • Role of neurotrophin receptor TrkB in the maturation of rod photoreceptors and establishment of synaptic transmission to the inner retina  Academic Article
  • Roles of Wnt proteins in neural development and maintenance  Academic Article
  • Senescent changes in a neurobiological model system - cerebellar purkinje-cell electrophysiology and correlative anatomy  Academic Article
  • Senescent microstructural changes in rat cerebellum  Academic Article
  • Senescent pathology of cerebellum - purkinje neurons and their parallel fiber afferents  Academic Article
  • Signaling mechanisms involved in the response to genotoxic stress and regulating lifespan  Academic Article
  • Skeletal muscle RBM3 expression is associated with extended lifespan in Ames Dwarf and calorie restricted mice  Academic Article
  • Slow-wave sleep: Do young adult men and women age differently?  Academic Article
  • Smad-dependent alterations of PPT cholinergic neurons as a pathophysiological mechanism of age-related sleep-dependent memory impairments  Academic Article
  • Smoking, fasting serum insulin, and obesity are the predictors of carotid atherosclerosis in relatively young subjects  Academic Article
  • Spectrin breakdown products increase with age in telencephalon of mouse-brain  Academic Article
  • Spermidine cures flies of senior moments  Academic Article
  • Sphingosine 1-phosphate S1P signaling is required for maintenance of hair cells mainly via activation of S1P2  Academic Article
  • Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging  Academic Article
  • Spontaneous glomerulonephritis in sheep  Academic Article
  • Stabilization of axon branch dynamics by synaptic maturation  Academic Article
  • Structures of the human LONP1 protease reveal regulatory steps involved in protease activation  Academic Article
  • Subchondral bone of the human knee in aging and osteoarthritis  Academic Article
  • Successful aging: From phenotype to genotype  Academic Article
  • Suppression of transcriptional drift extends C-elegans lifespan by postponing the onset of mortality  Academic Article
  • Surface and functional-characteristics of b-cells from lupus-prone murine strains  Academic Article
  • T cell homeostasis  Academic Article
  • T-cell repertoires in health and disease  Academic Article
  • Tau protein abnormalities associated with the progression of alzheimer disease type dementia  Academic Article
  • The 5-HT(5A) serotonin receptor is expressed predominantly by astrocytes in which it inhibits cAMP accumulation: a mechanism for neuronal suppression of reactive astrocytes  Academic Article
  • The Achilles' heel of senescent cells: from transcriptome to senolytic drugs  Academic Article
  • The Geropathology Research Network: An interdisciplinary approach for integrating pathology into research on aging  Academic Article
  • The aging face - a psychocutaneous perspective  Academic Article
  • The aging process: where are the drug opportunities?  Academic Article
  • The anemia of ageing is not associated with increased plasma hepcidin levels  Academic Article
  • The clinical potential of senolytic drugs  Academic Article
  • The effect of thymectomy on lupus-prone mice  Academic Article
  • The effects of aging on gene expression in the hypothalamus and cortex of mice  Academic Article
  • The growth hormone secretagogue receptor  Academic Article
  • The identification of zebrafish mutants showing alterations in senescence-associated biomarkers  Academic Article
  • The international olympic committee consensus statement on age determination in high-level young athletes  Academic Article
  • The kidneys of mice with autoimmune disease acquire a hypofibrinolytic/procoagulant state that correlates with the development of glomerulonephritis and tissue microthrombosis  Academic Article
  • The miR-17-92 cluster of microRNAs confers tumorigenicity by inhibiting oncogene-induced senescence  Academic Article
  • The no hypothesis - possible effects of a short-lived, rapidly diffusible signal in the development and function of the nervous-system  Academic Article
  • The oxidative DNA lesions 8,5'-cyclopurines accumulate with aging in a tissue-specific manner  Academic Article
  • The pathogenic activation of calpain: A marker and mediator of cellular toxicity and disease states  Academic Article
  • The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system  Academic Article
  • The regulation of dendritic arbor development and plasticity by glutamatergic synaptic input: A review of the synaptotrophic hypothesis  Academic Article
  • The relationship of autophagy defects to cartilage damage during joint aging in a mouse model  Academic Article
  • The search for evolutionary developmental origins of aging in zebrafish: a novel intersection of developmental and senescence biology in the zebrafish model system  Academic Article
  • The zebrafish as a vertebrate model of functional aging and very gradual senescence  Academic Article
  • Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies  Academic Article
  • Three-dimensional visualization of the smooth endoplasmic reticulum in Purkinje cell dendrites  Academic Article
  • Tissue-specific accelerated aging in nucleotide excision repair deficiency  Academic Article
  • Transgenic mice with a reduced core body temperature have an increased life span  Academic Article
  • Transthyretin and the brain re-visited: Is neuronal synthesis of transthyretin protective in Alzheimer's disease?  Academic Article
  • Tropomodulin1 is required for membrane skeleton organization and hexagonal geometry of fiber cells in the mouse lens  Academic Article
  • Two forms of 1B236/myelin-associated glycoprotein, a cell adhesion molecule for postnatal neural development, are produced by alternative splicing  Academic Article
  • Up-regulated expression of the phosphodiesterase nucleotide pyrophosphatase family member PC-1 is a marker and pathogenic factor for knee meniscal cartilage matrix calcification  Academic Article
  • Using zebrafish models to explore genetic and epigenetic impacts on evolutionary developmental origins of aging  Academic Article
  • V beta gene repertoire in the aging mouse: a developmental perspective  Academic Article
  • V-beta gene repertoires in aging mice  Academic Article
  • Vector prime/protein boost vaccine that overcomes defects acquired during aging and cancer  Academic Article
  • Virus-induced immunosuppression .1. Age at infection relates to a selective or generalized defect  Academic Article
  • White coat versus sustained borderline hypertension in Tecumseh, Michigan  Academic Article
  • Why are some amyloidoses systemic? Does hepatic "chaperoning at a distance" prevent cardiac deposition in a transgenic model of human senile systemic (transthyretin) amyloidosis?  Academic Article
  • Why is the New York Times writing so much about Alzheimer's disease therapies?  Academic Article
  • Zebrafish as a genetic model in biological and behavioral gerontology: where development meets aging in vertebrates. A mini-review  Academic Article

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