academic article

• von Drygalski, A., Bhat, V., Gale, A. J., Averell, P. M., Cramer, T. J., Elias, D. J., Griffin, J. H., Mosnier, L. O. An engineered factor Va prevents bleeding induced by direct-acting oral anticoagulants by different mechanisms Blood Advances  2020 4:3716-3727  DOI:10.1182/bloodadvances.2020001699  PMID:32777068  PMCID:PMC7422119
• Wyseure, T., Yang, T., Zhou, J. Y., Cooke, E. J., Wanko, B., Olmer, M., Agashe, R., Morodomi, Y., Behrendt, N., Lotz, M., Morser, J., von Drygalski, A., et al. TAFI deficiency causes maladaptive vascular remodeling after hemophilic joint bleeding JCI Insight  2019 4  DOI:10.1172/jci.insight.128379  PMID:31465300
• von Drygalski, A., Barnes, R. F. W., Jang, H., Ma, Y., Wong, J. H., Berman, Z., Du, J., Chang, E. Y. Advanced magnetic resonance imaging of cartilage components in haemophilic joints reveals that cartilage hemosiderin correlates with joint deterioration Haemophilia  2019 25:851-858  DOI:10.1111/hae.13802  PMID:31199035
• Zhou, J. Y., Barnes, R. F. W., Foster, G., Iorio, A., Cramer, T. J., von Drygalski, A. Joint bleeding tendencies in adult patients with hemophilia: it's not all pharmacokinetics Clinical and Applied Thrombosis-Hemostasis  2019 25  DOI:10.1177/1076029619862052  PMID:31298044
• Volland, L. M., Zhou, J. Y., Barnes, R. F. W., Kruse-Jarres, R., Steiner, B., Quon, D. V., Bailey, C., Hughes, T. H., Moore, R. E., Chang, E. Y., von Drygalski, A. Development and reliability of the joint tissue activity and damage examination for quantitation of structural abnormalities by musculoskeletal ultrasound in hemophilic joints Journal of Ultrasound in Medicine  2019 38:1569-1581  DOI:10.1002/jum.14846  PMID:30371941
• von Drygalski, A., Moore, R. E., Nguyen, S., Barnes, R. F. W., Volland, L. M., Hughes, T. H., Du, J., Chang, E. Y. Advanced hemophilic arthropathy: sensitivity of soft tissue discrimination with musculoskeletal ultrasound Journal of Ultrasound in Medicine  2018 37:1945-1955  DOI:10.1002/jum.14541  PMID:29363781  PMCID:PMC6057843
• Cooke, E. J., Zhou, J. Y., Wyseure, T., Joshi, S., Bhat, V., Durden, D. L., Mosnier, L. O., von Drygalski, A. Vascular permeability and remodelling coincide with inflammatory and reparative processes after joint bleeding in factor VIII-deficient mice Thrombosis and Haemostasis  2018 118:1036-1047  DOI:10.1055/s-0038-1641755  PMID:29847841
• Nguyen, S., Lu, X., Ma, Y., Du, J., Chang, E. Y., von Drygalski, A. Musculoskeletal ultrasound for intra-articular bleed detection: a highly sensitive imaging modality compared with conventional magnetic resonance imaging Journal of Thrombosis and Haemostasis  2018 16:490-499  DOI:10.1111/jth.13930  PMID:29274196  PMCID:PMC5826858
• Zhou, J. Y., Rappazzo, K. C., Volland, L., Barnes, R. F. W., Brackman, M., Steiner, B., Kruse-Jarres, R., Quon, D. V., Bailey, C., Chang, E. Y., von Drygalski, A. Pocket handheld ultrasound for evaluation of the bleeding haemophilic joint: A novel and reliable way to recognize joint effusions Haemophilia  2018 24:E77-E80  DOI:10.1111/hae.13429  PMID:29436079
• Huang, W. T., Cang, W. C., Derry, K. L., Lane, J. R., von Drygalski, A. Four-factor prothrombin complex concentrate for coagulopathy reversal in patients with liver disease Clinical and Applied Thrombosis-Hemostasis  2017 23:1028-1035  DOI:10.1177/1076029616668406  PMID:27628534
• Barnes, R. F. W., Cramer, T. J., Hughes, T. H., von Drygalski, A. The hypertension of hemophilia is associated with vascular remodeling in the joint Microcirculation  2017 24  DOI:10.1111/micc.12387  PMID:28627086
• Gale, A. J., Bhat, V., Pellequer, J. L., Griffin, J. H., Mosnier, L. O., Von Drygalski, A. Safety, stability and pharmacokinetic properties of (super)Factor Va, a novel engineered coagulation Factor V for treatment of severe bleeding Pharmaceutical Research  2016 33:1517-1526  DOI:10.1007/s11095-016-1895-3  PMID:26960296  PMCID:PMC4854778
• Cramer, T. J., Anderson, K., Navaz, K., Brown, J. M., Mosnier, L. O., von Drygalski, A. Heterozygous congenital Factor VII deficiency with the 9729de14 mutation, associated with severe spontaneous intracranial bleeding in an adolescent male Blood Cells Molecules and Diseases  2016 57:8-12  DOI:10.1016/j.bcmd.2015.11.004  PMID:26852649  PMCID:PMC4874642
• Bhat, V., von Drygalski, A., Gale, A. J., Griffin, J. H., Mosnier, L. O. Improved coagulation and haemostasis in haemophilia with inhibitors by combinations of superFactor Va and Factor VIIa Thrombosis and Haemostasis  2016 115:551-561  DOI:10.1160/th15-07-0525  PMID:26466980  PMCID:PMC4775351
• Wyseure, T., Mosnier, L. O., von Drygalski, A. Advances and challenges in hemophilic arthropathy Seminars in Hematology  2016 53:10-19  DOI:10.1053/j.seminhematol.2015.10.005  PMID:26805902  PMCID:PMC5034876
• Bhat, V., Olmer, M., Joshi, S., Durden, D. L., Cramer, T. J., Barnes, R. F. W., Ball, S. T., Hughes, T. H., Silva, M., Luck, J. V., Moore, R. E., Mosnier, L. O., et al. Vascular remodeling underlies rebleeding in hemophilic arthropathy American Journal of Hematology  2015 90:1027-1035  DOI:10.1002/ajh.24133  PMID:26257191  PMCID:PMC4618067
• von Drygalski, A., Bhat, V., Gale, A. J., Burnier, L., Cramer, T. J., Griffin, J. H., Mosnier, L. O. An engineered Factor Va prevents bleeding induced by anticoagulant wt activated protein C PLoS One  2014 9:e104304  DOI:10.1371/journal.pone.0104304  PMID:25127130  PMCID:PMC4134195
• von Drygalski, A., Cramer, T. J., Bhat, V., Griffin, J. H., Gale, A. J., Mosnier, L. O. Improved hemostasis in hemophilia mice by means of an engineered factor Va mutant Journal of Thrombosis and Haemostasis  2014 12:363-372  DOI:10.1111/jth.12489  PMID:24818532  PMCID:PMC4161283
• Macauley, M. S., Pfrengle, F., Rademacher, C., Nycholat, C. M., Gale, A. J., von Drygalski, A., Paulson, J. C. Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis Journal of Clinical Investigation  2013 123:3074-3083  DOI:10.1172/jci69187  PMID:23722906  PMCID:PMC3706185
• von Drygalski, A., Kolaitis, N. A., Bettencourt, R., Bergstrom, J., Kruse-Jarres, R., Quon, D. V., Wassel, C., Li, M. C., Waalen, J., Elias, D. J., Mosnier, L. O., Allison, M. Prevalence and risk factors for hypertension in hemophilia Hypertension  2013 62:209-215  DOI:10.1161/hypertensionaha.113.01174  PMID:23630949
• von Drygalski, A., Furlan-Freguia, C., Ruf, W., Griffin, J. H., Mosnier, L. O. Organ-specific protection against lipopolysaccharide-induced vascular leak is dependent on the endothelial protein C receptor Arteriosclerosis, Thrombosis, and Vascular Biology  2013 33:769-776  DOI:10.1161/atvbaha.112.301082  PMID:23393392
• von Drygalski, A., Furlan-Freguia, C., Mosnier, L. O., Yegneswaran, S., Ruf, W., Griffin, J. H. Infrared fluorescence for vascular barrier breach in vivo - a novel method for quantitation of albumin efflux Thrombosis and Haemostasis  2012 108:981-991  DOI:10.1160/th12-03-0196  PMID:23052565  PMCID:PMC3597782