recent publications
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academic article
- von Drygalski, A., Moore, R. E., Nguyen, S., Barnes, R. F. W., Volland, L. M., Hughes, T. H., Du, J., Chang, E. Y. Advanced hemophilic arthropathy: sensitivity of soft tissue discrimination with musculoskeletal ultrasound Journal of Ultrasound in Medicine 2018 37:1945-1955 DOI:10.1002/jum.14541 PMID:29363781 PMCID:PMC6057843
- Nguyen, S., Lu, X., Ma, Y., Du, J., Chang, E. Y., von Drygalski, A. Musculoskeletal ultrasound for intra-articular bleed detection: a highly sensitive imaging modality compared with conventional magnetic resonance imaging Journal of Thrombosis and Haemostasis 2018 16:490-499 DOI:10.1111/jth.13930 PMID:29274196 PMCID:PMC5826858
- Zhou, J. Y., Rappazzo, K. C., Volland, L., Barnes, R. F. W., Brackman, M., Steiner, B., Kruse-Jarres, R., Quon, D. V., Bailey, C., Chang, E. Y., von Drygalski, A. Pocket handheld ultrasound for evaluation of the bleeding haemophilic joint: A novel and reliable way to recognize joint effusions Haemophilia 2018 24:E77-E80 DOI:10.1111/hae.13429 PMID:29436079
- Cooke, E. J., Zhou, J. Y., Wyseure, T., Joshi, S., Bhat, V., Durden, D. L., Mosnier, L. O., von Drygalski, A. Vascular permeability and remodelling coincide with inflammatory and reparative processes after joint bleeding in factor VIII-deficient mice Thrombosis and Haemostasis 2018 118:1036-1047 DOI:10.1055/s-0038-1641755 PMID:29847841
- Huang, W. T., Cang, W. C., Derry, K. L., Lane, J. R., von Drygalski, A. Four-factor prothrombin complex concentrate for coagulopathy reversal in patients with liver disease Clinical and Applied Thrombosis-Hemostasis 2017 23:1028-1035 DOI:10.1177/1076029616668406 PMID:27628534
- Barnes, R. F. W., Cramer, T. J., Hughes, T. H., von Drygalski, A. The hypertension of hemophilia is associated with vascular remodeling in the joint Microcirculation 2017 24 DOI:10.1111/micc.12387 PMID:28627086
- Wyseure, T., Mosnier, L. O., von Drygalski, A. Advances and challenges in hemophilic arthropathy Seminars in Hematology 2016 53:10-19 DOI:10.1053/j.seminhematol.2015.10.005 PMID:26805902 PMCID:PMC5034876
- Cramer, T. J., Anderson, K., Navaz, K., Brown, J. M., Mosnier, L. O., von Drygalski, A. Heterozygous congenital Factor VII deficiency with the 9729de14 mutation, associated with severe spontaneous intracranial bleeding in an adolescent male Blood Cells Molecules and Diseases 2016 57:8-12 DOI:10.1016/j.bcmd.2015.11.004 PMID:26852649 PMCID:PMC4874642
- Bhat, V., von Drygalski, A., Gale, A. J., Griffin, J. H., Mosnier, L. O. Improved coagulation and haemostasis in haemophilia with inhibitors by combinations of superFactor Va and Factor VIIa Thrombosis and Haemostasis 2016 115:551-561 DOI:10.1160/th15-07-0525 PMID:26466980 PMCID:PMC4775351
- Gale, A. J., Bhat, V., Pellequer, J. L., Griffin, J. H., Mosnier, L. O., Von Drygalski, A. Safety, stability and pharmacokinetic properties of (super)Factor Va, a novel engineered coagulation Factor V for treatment of severe bleeding Pharmaceutical Research 2016 33:1517-1526 DOI:10.1007/s11095-016-1895-3 PMID:26960296 PMCID:PMC4854778
- Bhat, V., Olmer, M., Joshi, S., Durden, D. L., Cramer, T. J., Barnes, R. F. W., Ball, S. T., Hughes, T. H., Silva, M., Luck, J. V., Moore, R. E., Mosnier, L. O., et al. Vascular remodeling underlies rebleeding in hemophilic arthropathy American Journal of Hematology 2015 90:1027-1035 DOI:10.1002/ajh.24133 PMID:26257191 PMCID:PMC4618067
- von Drygalski, A., Bhat, V., Gale, A. J., Burnier, L., Cramer, T. J., Griffin, J. H., Mosnier, L. O. An engineered Factor Va prevents bleeding induced by anticoagulant wt activated protein C PLoS One 2014 9:e104304 DOI:10.1371/journal.pone.0104304 PMID:25127130 PMCID:PMC4134195
- von Drygalski, A., Cramer, T. J., Bhat, V., Griffin, J. H., Gale, A. J., Mosnier, L. O. Improved hemostasis in hemophilia mice by means of an engineered factor Va mutant Journal of Thrombosis and Haemostasis 2014 12:363-372 DOI:10.1111/jth.12489 PMID:24818532 PMCID:PMC4161283
- Macauley, M. S., Pfrengle, F., Rademacher, C., Nycholat, C. M., Gale, A. J., von Drygalski, A., Paulson, J. C. Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis Journal of Clinical Investigation 2013 123:3074-3083 DOI:10.1172/jci69187 PMID:23722906 PMCID:PMC3706185
- von Drygalski, A., Furlan-Freguia, C., Ruf, W., Griffin, J. H., Mosnier, L. O. Organ-specific protection against lipopolysaccharide-induced vascular leak is dependent on the endothelial protein C receptor Arteriosclerosis, Thrombosis, and Vascular Biology 2013 33:769-776 DOI:10.1161/atvbaha.112.301082 PMID:23393392
- von Drygalski, A., Kolaitis, N. A., Bettencourt, R., Bergstrom, J., Kruse-Jarres, R., Quon, D. V., Wassel, C., Li, M. C., Waalen, J., Elias, D. J., Mosnier, L. O., Allison, M. Prevalence and risk factors for hypertension in hemophilia Hypertension 2013 62:209-215 DOI:10.1161/hypertensionaha.113.01174 PMID:23630949
- von Drygalski, A., Furlan-Freguia, C., Mosnier, L. O., Yegneswaran, S., Ruf, W., Griffin, J. H. Infrared fluorescence for vascular barrier breach in vivo - a novel method for quantitation of albumin efflux Thrombosis and Haemostasis 2012 108:981-991 DOI:10.1160/th12-03-0196 PMID:23052565 PMCID:PMC3597782