recent publications

• academic article

  • Tsutakawa, S. E., Classen, S., Chapados, B. R., Arvai, A. S., Finger, L. D., Guenther, G., Tomlinson, C. G., Thompson, P., Sarker, A. H., Shen, B. H., Cooper, P. K., Grasby, J. A., et al. Human flap endonuclease structures, DNA double-base flipping, and a unified understanding of the fen1 superfamily Cell  2011 145:198-211  DOI:10.1016/j.cell.2011.03.004  PMID:21496641  PMCID:PMC3086263
  • Qiu, J. Z., Liu, R., Chapados, B. R., Sherman, M., Tainer, J. A., Shen, B. H. Interaction interface of human flap endonuclease-1 with its DNA substrates Journal of Biological Chemistry  2004 279:24394-24402  DOI:10.1074/jbc.M401464200  PMID:15037610
  • Chapados, B. R., Chai, Q., Hosfield, D. J., Qiu, J. Z., Shen, B. H., Tainer, J. A. Structural biochemistry of a type 2 rnase h: Rna primer recognition and removal during DNA replication Journal of Molecular Biology  2001 307:541-556  DOI:10.1006/jmbi.2001.4494  PMID:11254381
  • Shen, B. H., Qiu, J. Z., Hosfield, D., Tainer, J. A. Flap endonuclease homologs in archaebacteria exist as independent proteins Trends in Biochemical Sciences  1998 23:171-173  DOI:10.1016/s0968-0004(98)01199-2  PMID:9612080
  • Hosfield, D. J., Mol, C. D., Shen, B. H., Tainer, J. A. Structure of the DNA repair and replication endonuclease and exonuclease fen-1: Coupling DNA and pcna binding to fen-1 activity Cell  1998 95:135-146  DOI:10.1016/s0092-8674(00)81789-4  PMID:9778254
  • Kemper, M. A., Stout, C. D., Lloyd, S. E. J., Prasad, G. S., Fawcett, S., Armstrong, F. A., Shen, B. H., Burgess, B. K. Y13c azotobacter vinelandii ferredoxin i - a designed fe-s ligand motif contains a cysteine persulfide Journal of Biological Chemistry  1997 272:15620-15627  DOI:10.1074/jbc.272.25.15620  PMID:9188450
  • Shen, B. H., Jollie, D. R., Stout, C. D., Diller, T. C., Armstrong, F. A., Gorst, C. M., Lamar, G. N., Stephens, P. J., Burgess, B. K. Azotobacter-vinelandii ferredoxin-i - alteration of individual surface-charges and the 4fe-4s (2+/+) cluster reduction potential Journal of Biological Chemistry  1994 269:8564-8575  PMID:8132582
  • Shen, B. H., Martin, L. L., Butt, J. N., Armstrong, F. A., Stout, C. D., Jensen, G. M., Stephens, P. J., Lamar, G. N., Gorst, C. M., Burgess, B. K. Azotobacter-vinelandii ferredoxin-i - aspartate-15 facilitates proton-transfer to the reduced 3fe-4s cluster Journal of Biological Chemistry  1993 268:25928-25939  PMID:8245026