recent publications

• academic article

  • Hart, J. R., Garner, A. L., Yu, J., Ito, Y., Sun, M. H., Ueno, L., Rhee, J. K., Baksh, M. M., Stefan, E., Hartl, M., Bister, K., Vogt, P. K., et al. Inhibitor of MYC identified in a Krohnke pyridine library Proceedings of the National Academy of Sciences of the United States of America  2014 111:12556-12561  DOI:10.1073/pnas.1319488111  PMID:25114221  PMCID:PMC4151726
  • Kravchenko, V., Garner, A. L., Mathison, J., Seit-Nebi, A., Yu, J., Gileva, I. P., Ulevitch, R., Janda, K. D. Facilitating cytokine-mediated cancer cell death by proteobacterial N-acylhomoserine lactones ACS Chemical Biology  2013 1117-1120  DOI:10.1021/cb4000184  PMID:23517377  PMCID:PMC3755046
  • Fullagar, J. L., Garner, A. L., Struss, A. K., Day, J. A., Martin, D. P., Yu, J., Cai, X., Janda, K. D., Cohen, S. M. Antagonism of a zinc metalloprotease using a unique metal-chelating scaffold: Tropolones as inhibitors of p. Aeruginosa elastase Chemical Communications  2013 49:3197-9  DOI:10.1039/c3cc41191e  PMID:23482955  PMCID:PMC3618488
  • Garner, A. L., Yu, J., Struss, A. K., Kaufmann, G. F., Kravchenko, V. V., Janda, K. D. Immunomodulation and the quorum sensing molecule 3-oxo-C-12-homoserine lactone: The importance of chemical scaffolding for probe development Chemical Communications  2013 49:1515-1517  DOI:10.1039/c3cc38851d  PMID:23328974  PMCID:PMC3566768
  • Garner, A. L., Yu, J., Struss, A. K., Lowery, C. A., Zhu, J., Kim, S. K., Park, J., Mayorov, A. V., Kaufmann, G. F., Kravchenko, V. V., Janda, K. D. Synthesis of 'clickable' acylhomoserine lactone quorum sensing probes: Unanticipated effects on mammalian cell activation Bioorganic & Medicinal Chemistry Letters  2011 21:2702-2705  DOI:10.1016/j.bmcl.2010.11.122  PMID:21190852  PMCID:PMC3081916
  • Li, X. F., Zhang, S., Zhang, H. W., Zhang, L. H., Tao, H. T., Yu, J., Zheng, W. J., Liu, C. H., Lu, D., Xiang, R., Liu, Y. A loop-mediated isothermal amplification method targets the phop gene for the detection of salmonella in food samples International Journal of Food Microbiology  2009 133:252-258  DOI:10.1016/j.ijfoodmicro.2009.05.027  PMID:19540609
  • Aller, S. G., Yu, J., Ward, A., Weng, Y., Chittaboina, S., Zhuo, R. P., Harrell, P. M., Trinh, Y. T., Zhang, Q. H., Urbatsch, I. L., Chang, G. Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding Science  2009 323:1718-1722  DOI:10.1126/science.1168750  PMID:19325113  PMCID:PMC2720052
  • Garrison, S. P., Jeffers, J. R., Yang, C. Y., Nilsson, J. A., Hall, M. A., Rehg, J. E., Yue, W., Yu, J., Zhang, L., Onciu, M., Sample, J. T., Cleveland, J. L., et al. Selection against puma gene expression in myc-driven b-cell lymphomagenesis Molecular and Cellular Biology  2008 28:5391-5402  DOI:10.1128/mcb.00907-07  PMID:18573879  PMCID:PMC2519737
  • Ward, A., Reyes, C. L., Yu, J., Roth, C. B., Chang, G. Flexibility in the ABC transporter MsbA: Alternating access with a twist Proceedings of the National Academy of Sciences of the United States of America  2007 104:19005-19010  DOI:10.1073/pnas.0709388104  PMID:18024585  PMCID:PMC2141898
  • Frazer, K. A., Ballinger, D. G., Cox, D. R., Hinds, D. A., Stuve, L. L., Gibbs, R. A., Belmont, J. W., Boudreau, A., Hardenbol, P., Leal, S. M., Pasternak, S., Wheeler, D. A., et al. A second generation human haplotype map of over 3.1 million SNPs Nature  2007 449:851-861  DOI:10.1038/nature06258  PMID:17943122  PMCID:PMC2689609
  • Sabeti, P. C., Varilly, P., Fry, B., Lohmueller, J., Hostetter, E., Cotsapas, C., Xie, X. H., Byrne, E. H., McCarroll, S. A., Gaudet, R., Schaffner, S. F., Lander, E. S. Genome-wide detection and characterization of positive selection in human populations Nature  2007 449:913-918  DOI:10.1038/nature06250  PMID:17943131  PMCID:PMC2687721
  • Heisler, L. K., Jobst, E. E., Sutton, G. M., Zhou, L. G., Borok, E., Thornton-Jones, Z., Liu, H. Y., Zigman, J. M., Balthasar, N., Kishi, T., Lee, C. E., Aschkenasi, C. J., et al. Serotonin reciprocally regulates melanocortin neurons to modulate food intake Neuron  2006 51:239-249  DOI:10.1016/j.neuron.2006.06.004  PMID:16846858
  • Reyes, C. L., Ward, A., Yu, J., Chang, G. The structures of MsbA: Insight into ABC transporter-mediated multidrug efflux FEBS Letters  2006 580:1042-1048  DOI:10.1016/j.febslet.2005.11.033  PMID:16337944
  • Zhang, L. Q., Zhang, F. W., Yu, W. J., He, T., Yu, J., Yi, C. E., Ba, L., Li, W. H., Farzan, M., Chen, Z. W., Yuen, K. Y., Ho, D. Antibody responses against SARS coronavirus are correlated with disease outcome of infected individuals Journal of Medical Virology  2006 78:1-8  DOI:10.1002/jmv.20499  PMID:16299724
  • Altshuler, D., Brooks, L. D., Chakravarti, A., Collins, F. S., Daly, M. J., Donnelly, P., Gibbs, R. A., Belmont, J. W., Boudreau, A., Leal, S. M., Hardenbol, P., Pasternak, S., et al. A haplotype map of the human genome Nature  2005 437:1299-1320  DOI:10.1038/nature04226  PMID:16255080  PMCID:PMC1880871
  • Chen, Z. W., Zhang, L. Q., Qin, C. A., Ba, L., Yi, C. E., Zhang, F. W., Wei, Q., He, T., Yu, W. J., Yu, J., Gao, H., Tu, X. M., et al. Recombinant modified vaccinia virus Ankara expressing the spike glycoprotein of severe acute respiratory syndrome coronavirus induces protective neutralizing antibodies primarily targeting the receptor binding region Journal of Virology  2005 79:2678-2688  DOI:10.1128/jvi.79.5.2678-2688.2005  PMID:15708987
  • Yu, J., Choi, S. Y., Lee, S., Yoon, H. J., Jeong, S., Mun, H., Park, H., Schultz, P. G. Antibody-catalysed glycosyl transfer reactions from in vitro immunization Chemical Communications  1997 1957-1958  DOI:10.1039/a704885h
  • Tans, G., Verkleij, A. J., Yu, J., Griffin, J. H. Sulfatide bilayers as a surface for contact activation in human plasma Biochemical and Biophysical Research Communications  1987 149:1002-1007  DOI:10.1016/0006-291x(87)90508-0  PMID:3426605