recent publications
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academic article
- Mari, Y., West, G. M., Scharager-Tapia, C., Pascal, B. D., Garcia-Ordonez, R. D., Griffin, P. R. SERBP1 Is a component of the liver receptor homologue-1 transcriptional complex Journal of Proteome Research 2015 14:4571-4580 DOI:10.1021/acs.jproteome.5b00379 PMID:26398198
- West, G. M., Willard, F. S., Sloop, K. W., Showalter, A. D., Pascal, B. D., Griffin, P. R. Glucagon-like peptide-1 receptor ligand interactions: structural cross talk between ligands and the extracellular domain PLoS One 2014 9:e105683 DOI:10.1371/journal.pone.0105683 PMID:25180755 PMCID:PMC4152014
- West, G. M., Pascal, B. D., Ng, L. M., Soon, F. F., Melcher, K., Xu, H. E., Chalmers, M. J., Griffin, P. R. Protein conformation ensembles monitored by HDX reveal a structural rationale for abscisic acid signaling protein affinities and activities Structure 2013 21:229-235 DOI:10.1016/j.str.2012.12.001 PMID:23290725 PMCID:PMC3570687
- Pascal, B. D., Willis, S., Lauer, J. L., Landgraf, R. R., West, G. M., Marciano, D., Novick, S., Goswami, D., Chalmers, M. J., Griffin, P. R. HDX workbench: software for the analysis of H/D exchange MS data Journal of the American Society for Mass Spectrometry 2012 23:1512-1521 DOI:10.1007/s13361-012-0419-6 PMID:22692830 PMCID:PMC3808162
- Soon, F. F., Ng, L. M., Zhou, X. E., West, G. M., Kovach, A., Tan, M. H. E., Suino-Powell, K. M., He, Y. Z., Xu, Y., Chalmers, M. J., Brunzelle, J. S., Zhang, H. M., et al. Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases Science 2012 335:85-88 DOI:10.1126/science.1215106 PMID:22116026 PMCID:PMC3584687
- Chalmers, M. J., Busby, S. A., Pascal, B. D., West, G. M., Griffin, P. R. Differential hydrogen/deuterium exchange mass spectrometry analysis of protein-ligand interactions Expert Review of Proteomics 2011 8:43-59 DOI:10.1586/epr.10.109 PMID:21329427 PMCID:PMC3113475
- West, G. M., Chien, E. Y. T., Katritch, V., Gatchalian, J., Chalmers, M. J., Stevens, R. C., Griffin, P. R. Ligand-dependent perturbation of the conformational ensemble for the GPCR beta(2) adrenergic receptor revealed by HDX Structure 2011 19:1424-1432 DOI:10.1016/j.str.2011.08.001 PMID:21889352 PMCID:PMC3196059
- Ng, L. M., Soon, F. F., Zhou, X. E., West, G. M., Kovach, A., Suino-Powell, K. M., Chalmers, M. J., Li, J., Yong, E. L., Zhu, J. K., Griffin, P. R., Melcher, K., et al. Structural basis for basal activity and autoactivation of abscisic acid (ABA) signaling SnRK2 kinases Proceedings of the National Academy of Sciences of the United States of America 2011 108:21259-21264 DOI:10.1073/pnas.1118651109 PMID:22160701 PMCID:PMC3248506
- West, G. M., Tucker, C. L., Xu, T., Park, S. K., Han, X. M., Yates, J. R., Fitzgerald, M. C. Quantitative proteomics approach for identifying protein-drug interactions in complex mixtures using protein stability measurements Proceedings of the National Academy of Sciences of the United States of America 2010 107:9078-9082 DOI:10.1073/pnas.1000148107 PMID:20439767 PMCID:PMC2889096