recent publications

• academic article

  • Karakasilioti, I., Kamileri, I., Chatzinikolaou, G., Kosteas, T., Vergadi, E., Robinson, A. R., Tsamardinos, I., Rozgaja, T. A., Siakouli, S., Tsatsanis, C., Niedernhofer, L. J., Garinis, G. A. DNA damage triggers a chronic autoinflammatory response, leading to fat depletion in NER progeria Cell Metabolism  2013 18:403-415  DOI:10.1016/j.cmet.2013.08.011  PMID:24011075  PMCID:PMC4116679
  • Tilstra, J. S., Robinson, A. R., Wang, J., Gregg, S. Q., Clauson, C. L., Reay, D. P., Nasto, L. A., St Croix, C. M., Usas, A., Vo, N., Huard, J., Clemens, P. R., et al. NF-kB inhibition delays DNA damage-induced senescence and aging in mice Journal of Clinical Investigation  2012 122:2601-2612  DOI:10.1172/jci45785  PMID:22706308  PMCID:PMC3386805
  • Schumacher, B., van der Pluijm, I., Moorhouse, M. J., Kosteas, T., Robinson, A. R., Suh, Y., Breit, T. M., van Steeg, H., Niedernhofer, L. J., van Ijcken, W., Bartke, A., Spindler, S. R., et al. Delayed and accelerated aging share common longevity assurance mechanisms PLoS Genetics  2008 4:e1000161  DOI:10.1371/journal.pgen.1000161  PMID:18704162  PMCID:PMC2493043
  • van der Pluijm, I., Garinis, G. A., Brandt, R. M. C., Gorgels, Tgmf, Wijnhoven, S. W., Diderich, K. E. M., de Wit, J., Mitchell, J. R., van Oostrom, C., Beems, R., Niedernhofer, L. J., Velasco, S., et al. Impaired genome maintenance suppresses the growth hormone-insulin-like growth factor 1 axis in mice with cockayne syndrome PLoS Biology  2007 5:23-38  DOI:10.1371/journal.pbio.0050002  PMID:17326724  PMCID:PMC1698505
  • Niedernhofer, L. J., Garinis, G. A., Raams, A., Lalai, A. S., Robinson, A. R., Appeldoorn, E., Odijk, H., Oostendorp, R., Ahmad, A., Van Leeuwen, W., Theil, A. F., Vermeulen, W., et al. A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis Nature  2006 444:1038-1043  DOI:10.1038/nature05456  PMID:17183314