recent publications

• academic article

  • Clauson, C., Scharer, O. D., Niedernhofer, L. Advances in understanding the complex mechanisms of DNA interstrand cross-link repair Cold Spring Harbor Perspectives in Biology  2013 5:a012732  DOI:10.1101/cshperspect.a012732  PMID:24086043  PMCID:PMC3783045
  • Su, Y., Orelli, B., Madireddy, A., Niedernhofer, L. J., Scharer, O. D. Multiple DNA binding domains mediate the function of the ERCC1-XPF protein in nucleotide excision repair Journal of Biological Chemistry  2012 287:21846-21855  DOI:10.1074/jbc.M111.337899  PMID:22547097  PMCID:PMC3381147
  • Ahmad, A., Enzlin, J. H., Bhagwat, N. R., Wijgers, N., Raams, A., Appledoorn, E., Theil, A. F., Hoeijmakers, J. H. J., Vermeulen, W., Jaspers, N. G. J., Scharer, O. D., Niedernhofer, L. J. Mislocalization of XPF-ERCC1 nuclease contributes to reduced DNA repair in XP-F patients PLoS Genetics  2010 6:e1000871  DOI:10.1371/journal.pgen.1000871  PMID:20221251  PMCID:PMC2832669
  • Orelli, B., McClendon, T. B., Tsodikov, O. V., Ellenberger, T., Niedernhofer, L. J., Scharer, O. D. The XPA-binding domain of ERCC1 is required for nucleotide excision repair but not other DNA repair pathways Journal of Biological Chemistry  2010 285:3705-3712  DOI:10.1074/jbc.M109.067538  PMID:19940136  PMCID:PMC2823511