recent publications
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academic article
- Malyshev, D. A., Dhami, K., Lavergne, T., Chen, T., Dai, N., Foster, J. M., Correa Jr., I. R., Romesberg, F. E. A semi-synthetic organism with an expanded genetic alphabet Nature 2014 509:385-388 DOI:10.1038/nature13314 PMID:24805238 PMCID:PMC4058825
- Li, L., Degardin, M., Lavergne, T., Malyshev, D. A., Dhami, K., Ordoukhanian, P., Romesberg, F. E. Natural-like replication of an unnatural base pair for the expansion of the genetic alphabet and biotechnology applications Journal of the American Chemical Society 2014 136:826-829 DOI:10.1021/ja408814g PMID:24152106 PMCID:PMC3979842
- Dhami, K., Malyshev, D. A., Ordoukhanian, P., Kubelka, T., Hocek, M., Romesberg, F. E. Systematic exploration of a class of hydrophobic unnatural base pairs yields multiple new candidates for the expansion of the genetic alphabet Nucleic Acids Research 2014 42:10235-10244 DOI:10.1093/nar/gku715 PMID:25122747 PMCID:PMC4176363
- Lavergne, T., Degardin, M., Malyshev, D. A., Quach, H. T., Dhami, K., Ordoukhanian, P., Romesberg, F. E. Expanding the scope of replicable unnatural DNA: Stepwise optimization of a predominantly hydrophobic base pair Journal of the American Chemical Society 2013 DOI:10.1021/ja312148q PMID:23547847 PMCID:PMC3690937
- Li, Z., Lavergne, T., Malyshev, D. A., Zimmermann, J., Adhikary, R., Dhami, K., Ordoukhanian, P., Sun, Z., Xiang, J., Romesberg, F. E. Site-specifically arraying small molecules or proteins on DNA using an expanded genetic alphabet Chemistry-a European Journal 2013 19:14205-14209 DOI:10.1002/chem.201302496 PMID:24026962 PMCID:PMC3983968
- Malyshev, D. A., Dhami, K., Quach, H. T., Lavergne, T., Ordoukhanian, P., Torkamani, A., Romesberg, F. E. Efficient and sequence-independent replication of DNA containing a third base pair establishes a functional six-letter genetic alphabet Proceedings of the National Academy of Sciences of the United States of America 2012 109:12005-12010 DOI:10.1073/pnas.1205176109 PMID:22773812 PMCID:PMC3409741