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Sustained local delivery of structurally diverse HIV-1 microbicides released from sublimation enthalpy controlled matrices

Academic Article
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Overview

authors

  • Gunaseelan, S.
  • Gallay, Philippe
  • Bobardt, M. D.
  • Dezzutti, C. S.
  • Esch, T.
  • Maskiewicz, R.

publication date

  • November 2012

journal

  • Pharmaceutical Research  Journal

subject areas

  • Adenine
  • Animals
  • Anti-HIV Agents
  • Cells, Cultured
  • Contraceptive Devices, Female
  • Delayed-Action Preparations
  • Deoxycytidine
  • Drug Delivery Systems
  • Emtricitabine
  • Female
  • HIV Infections
  • HIV-1
  • Humans
  • Macrophages
  • Monocytes
  • Organophosphonates
  • Sheep
  • Structure-Activity Relationship
  • Sublimation
  • T-Lymphocytes
  • Tenofovir
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Research

keywords

  • HIV-1
  • enthalpically controlled release
  • intravaginal delivery
  • prolonged antiviral effect
  • subliming solid matrix
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Identity

PubMed Central ID

  • PMC3473190

International Standard Serial Number (ISSN)

  • 0724-8741

Digital Object Identifier (DOI)

  • 10.1007/s11095-012-0811-8

PubMed ID

  • 22736232
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Additional Document Info

start page

  • 3156

end page

  • 3168

volume

  • 29

issue

  • 11

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