recent publications

• academic article

  • Fazzi, F., Njah, J., Di Giuseppe, M., Winnica, D. E., Go, K., Sala, E., St Croix, C. M., Watkins, S. C., Tyurin, V. A., Phinney, D. G., Fattman, C. L., Leikauf, G. D., et al. TNFR1/phox interaction and TNFR1 mitochondrial translocation Thwart silica-induced pulmonary fibrosis Journal of Immunology  2014 192:3837-3846  DOI:10.4049/jimmunol.1103516  PMID:24623132  PMCID:PMC3977215
  • Tilstra, J. S., Robinson, A. R., Wang, J., Gregg, S. Q., Clauson, C. L., Reay, D. P., Nasto, L. A., St Croix, C. M., Usas, A., Vo, N., Huard, J., Clemens, P. R., et al. NF-kB inhibition delays DNA damage-induced senescence and aging in mice Journal of Clinical Investigation  2012 122:2601-2612  DOI:10.1172/jci45785  PMID:22706308  PMCID:PMC3386805
  • Vo, N., Seo, H. Y., Robinson, A., Sowa, G., Bentley, D., Taylor, L., Studer, R., Usas, A., Huard, J., Alber, S., Watkins, S. C., Lee, J., et al. Accelerated aging of intervertebral discs in a mouse model of progeria Journal of Orthopaedic Research  2010 28:1600-1607  DOI:10.1002/jor.21153  PMID:20973062  PMCID:PMC3477798
  • Zahid, M., Phillips, B. E., Albers, S. M., Giannoukakis, N., Watkins, S. C., Robbins, P. D. Identification of a cardiac specific protein transduction domain by in vivo biopanning using a M13 phage peptide display library in mice PLoS One  2010 5:e12252  DOI:10.1371/journal.pone.0012252  PMID:20808875  PMCID:PMC2923200
  • Montecalvo, A., Shufesky, W. J., Stolz, D. B., Sullivan, M. G., Wang, Z. L., Divito, S. J., Papworth, G. D., Watkins, S. C., Robbins, P. D., Larregina, A. T., Morelli, A. E. Exosomes as a short-range mechanism to spread alloantigen between dendiritic cells during T cell allorecognition Journal of Immunology  2008 180:3081-3090  PMID:18292531
  • Evans, C. H., Robbins, P. D., Ghivizzani, S. C., Wasko, M. C., Tomaino, M. M., Kang, R., Muzzonigro, T. A., Vogt, M., Elder, E. M., Whiteside, T. L., Watkins, S. C., Herndon, J. H. Gene transfer to human joints: progress toward a gene therapy of arthritis Proceedings of the National Academy of Sciences of the United States of America  2005 102:8698-8703  DOI:10.1073/pnas.0502854102  PMID:15939878  PMCID:PMC1150836
  • Kim, S. H., Lechman, E. R., Bianco, N., Menon, R., Keravala, A., Nash, J., Mi, Z. B., Watkins, S. C., Gambotto, A., Robbins, P. D. Exosomes derived from IL-10-treated dendritic cells can suppress inflammation and collagen-induced arthritis Journal of Immunology  2005 174:6440-6448  PMID:15879146
  • Mahidhara, R. S., De Oliveira, P. E. Q., Kohout, J., Beer, D. G., Lin, J. Y., Watkins, S. C., Robbins, P. D., Hughes, S. J. Altered trafficking of FAS and subsequent resistance to FAS-mediated apoptosis occurs by a wild-type p53 independent mechanism in esophageal adenocarcinoma Journal of Surgical Research  2005 123:302-311  DOI:10.1016/j.jss.2004.08.016  PMID:15680394
  • Bertera, S., Alexander, A. M., Crawford, M. L., Papworth, G., Watkins, S. C., Robbins, P. D., Trucco, M. Gene combination transfer to block autoimmune damage in transplanted islets of Langerhans Experimental Diabesity Research  2004 5:201-210  DOI:10.1080/15438600490486822  PMID:15512788  PMCID:PMC2478630
  • Tatsumi, T., Huang, J., Gooding, W. E., Gambotto, A., Robbins, P. D., Vujanovic, N. L., Alber, S. M., Watkins, S. C., Okada, H., Storkus, W. J. Intratumoral delivery of dendritic cells engineered to secrete both interleukin (IL)-12 and IL-18 effectively treats local and distant disease in association with broadly reactive Tc1-type immunity Cancer Research  2003 63:6378-6386  PMID:14559827
  • Mi, Z. B., Lu, X. L., Mai, J. C., Bobby, G. N., Wang, G. Q., Lechman, E. R., Watkins, S. C., Rabinowich, H., Robbins, P. D. Identification of a synovial fibroblast-specific protein transduction domain for delivery of apoptotic agents to hyperplastic synovium Molecular Therapy  2003 8:295-305  DOI:10.1016/s1525-016(03)00181-3  PMID:12907152
  • Bertera, S., Crawford, M. L., Alexander, A. M., Papworth, G. D., Watkins, S. C., Robbins, P. D., Trucco, M. Gene transfer of manganese superoxide dismutase extends islet graft function in a mouse model of autoimmune diabetes Diabetes  2003 52:387-393  PMID:12540612
  • Feili-Hariri, M., Falkner, D. H., Gambotto, A., Papworth, G. D., Watkins, S. C., Robbins, P. D., Morel, P. A. Dendritic cells transduced to express interleukin-4 prevent diabetes in nonobese diabetic mice with advanced insulitis Human Gene Therapy  2003 14:13-23  DOI:10.1089/10430340360464679  PMID:12573055
  • Mai, J. C., Shen, H. M., Watkins, S. C., Cheng, T., Robbins, P. D. Efficiency of protein transduction is cell type-dependent and is enhanced by dextran sulfate Journal of Biological Chemistry  2002 277:30208-30218  DOI:10.1074/jbc.M204202200  PMID:12034749
  • Li, Y. Y., Mi, Z. B., Feng, Y. Q., McTiernan, C. F., Zhou, R. P., Robbins, P. D., Watkins, S. C., Feldman, A. M. Differential effects of overexpression of two forms of ephrin-A5 on neonatal rat cardiomyocytes American Journal of Physiology-Heart and Circulatory Physiology  2001 281:H2738-H2746  PMID:11709443
  • Kadokami, T., McTiernan, C. F., Kubota, T., Frye, C. S., Bounoutas, G. S., Robbins, P. D., Watkins, S. C., Feldman, A. M. Effects of soluble TNF receptor treatment on lipopolysaccharide-induced myocardial cytokine expression American Journal of Physiology-Heart and Circulatory Physiology  2001 280:H2281-H2291  PMID:11299232
  • Howard, M., Jiang, X. S., Stolz, D. B., Hill, W. G., Johnson, J. A., Watkins, S. C., Frizzell, R. A., Bruton, C. M., Robbins, P. D., Weisz, O. A. Forskolin-induced apical membrane insertion of virally expressed, epitope-tagged CFTR in polarized MDCK cells American Journal of Physiology-Cell Physiology  2000 279:C375-C382  PMID:10913004
  • Hirao, M., Onai, N., Hiroishi, K., Watkins, S. C., Matsushima, K., Robbins, P. D., Lotze, M. T., Tahara, H. Cc chemokine receptor-7 on dendritic cells is induced after interaction with apoptotic tumor cells: Critical role in migration from the tumor site to draining lymph nodes Cancer Research  2000 60:2209-2217  PMID:10786686
  • Ranieri, E., Herr, W., Gambotto, A., Olson, W., Rowe, D., Robbins, P. D., Kierstead, L. S., Watkins, S. C., Gesualdo, L., Storkus, W. J. Dendritic cells transduced with an adenovirus vector encoding Epstein-Barr virus latent membrane protein 2B: A new modality for vaccination Journal of Virology  1999 73:10416-10425  PMID:10559360  PMCID:PMC113097
  • Esche, C., Gambotto, A., Satoh, Y., Gerein, V., Robbins, P. D., Watkins, S. C., Lotze, M. T., Shurin, M. R. CD154 inhibits tumor-induced apoptosis in dendritic cells and tumor growth European Journal of Immunology  1999 29:2148-2155  DOI:10.1002/(sici)1521-4141(199907)29:07<2148::aid-immu2148>3.0.co;2-f  PMID:10427977
  • Ghivizzani, S. C., Kang, R., Georgescu, H. I., Lechman, E. R., Jaffurs, D., Engle, J. M., Watkins, S. C., Tindal, M. H., Suchanek, M. K., McKenzie, L. R., Evans, C. H., Robbins, P. D. Constitutive intra-articular expression of human IL-1 beta following gene transfer to rabbit synovium produces all major pathologies of human rheumatoid arthritis Journal of Immunology  1997 159:3604-3612  PMID:9317160
  • Henderson, R. A., Nimgaonkar, M. T., Watkins, S. C., Robbins, P. D., Ball, E. D., Finn, O. J. Human dendritic cells genetically engineered to express high levels of the human epithelial tumor antigen mucin (MUC-1) Cancer Research  1996 56:3763-3770  PMID:8706022
  • Tzeng, E., Shears, L. L., Robbins, P. D., Pitt, B. R., Geller, D. A., Watkins, S. C., Simmons, R. L., Billiar, T. R. Vascular gene transfer of the human inducible nitric oxide synthase: Characterization of activity and effects on myointimal hyperplasia Molecular Medicine  1996 2:211-225  PMID:8726464  PMCID:PMC2230119
  • Mueller, G. M., McKenzie, L. R., Homanics, G. E., Watkins, S. C., Robbins, P. D., Paul, H. S. Complementation of defective leucine decarboxylation in fibroblasts from a maple syrup urine disease patient by retrovirus-mediated gene transfer Gene Therapy  1995 2:461-468  PMID:7584124
  • Tahara, H., Zeh, H. J., Storkus, W. J., Pappo, I., Watkins, S. C., Gubler, U., Wolf, S. F., Robbins, P. D., Lotze, M. T. Fibroblasts genetically engineered to secrete interleukin 12 can suppress tumor growth and induce antitumor immunity to a murine melanoma in vivo Cancer Research  1994 54:182-189  PMID:7903204
  • Calmels, T. P. G., Mistry, J. S., Watkins, S. C., Robbins, P. D., McGuire, R., Lazo, J. S. Nuclear-localization of bacterial Streptoalloteichus-hindustanus bleomycin resistance protein in mammalian-cells Molecular Pharmacology  1993 44:1135-1141  PMID:7505390