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Cerebrospinal-fluid levels of beta-endorphin in patients with fibromyalgia (fibrositis syndrome)

Academic Article
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Overview

authors

  • Vaeroy, H.
  • Helle, R.
  • Forre, O.
  • Kass, E.
  • Terenius, Lars

publication date

  • December 1988

journal

  • Journal of Rheumatology  Journal

abstract

  • Cerebrospinal fluid (CSF) samples from 18 female patients with fibromyalgia (fibrositis syndrome) were analyzed for beta-endorphin. The mean CSF level of beta-endorphin was 20.7 +/- 0.7 fmol/ml in the patients compared to 20.5 +/- 2.0 fmol/ml (mean +/- SEM) in healthy controls (p greater than 0.05). Thus, patients with fibromyalgia (fibrositis syndrome) seem to have normal CSF levels of the pain modulatory neuropeptide beta-endorphin.

subject areas

  • Adult
  • Female
  • Fibromyalgia
  • Humans
  • Middle Aged
  • Radioimmunoassay
  • Substance P
  • beta-Endorphin
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Identity

International Standard Serial Number (ISSN)

  • 0315-162X

PubMed ID

  • 2466120
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Additional Document Info

start page

  • 1804

end page

  • 1806

volume

  • 15

issue

  • 12

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