recent publications

• academic article

  • Zhang, H., de Vries, R. P., Tzarum, N., Zhu, X., Yu, W., McBride, R., Paulson, J. C., Wilson, I. A. A human-infecting H10N8 influenza virus retains a strong preference for avian-type receptors Cell Host & Microbe  2015 17:377-384  DOI:10.1016/j.chom.2015.02.006  PMID:25766296  PMCID:PMC4359746
  • Impagliazzo, A., Milder, F., Kuipers, H., Wagner, M. V., Zhu, X., Hoffman, R. M. B., van Meersbergen, R., Huizingh, J., Wanningen, P., Verspuij, J., de Man, M., Ding, Z., et al. A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen Science  2015 349:1301-1306  DOI:10.1126/science.aac7263  PMID:26303961
  • Perryman, A. L., Yu, W., Wang, X., Ekins, S., Forli, S., Li, S. G., Freundlich, J. S., Tonge, P. J., Olson, A. J. A virtual screen discovers novel, fragment-sized inhibitors of mycobacterium tuberculosis InhA Journal of Chemical Information and Modeling  2015 55:645-659  DOI:10.1021/ci500672v  PMID:25636146  PMCID:PMC4386068
  • Lee, P. S., Zhu, X., Yu, W., Wilson, I. A. Design and structure of an engineered disulfide-stabilized influenza virus hemagglutinin trimer Journal of Virology  2015 89:7417-7420  DOI:10.1128/jvi.00808-15  PMID:25926650  PMCID:PMC4473583
  • Tzarum, N., de Vries, R. P., Zhu, X., Yu, W., McBride, R., Paulson, J. C., Wilson, I. A. Structure and receptor binding of the hemagglutinin from a human H6N1 influenza virus Cell Host & Microbe  2015 17:369-376  DOI:10.1016/j.chom.2015.02.005  PMID:25766295  PMCID:PMC4374348
  • Friesen, R. H. E., Lee, P. S., Stoop, E. J. M., Hoffman, R. M. B., Ekiert, D. C., Bhabha, G., Yu, W., Juraszek, J., Koudstaal, W., Jongeneelen, M., Korse, H. J. W. M., Ophorst, C., et al. A common solution to group 2 influenza virus neutralization Proceedings of the National Academy of Sciences of the United States of America  2014 111:445-450  DOI:10.1073/pnas.1319058110  PMID:24335589  PMCID:PMC3890827
  • de Vries, R. P., Zhu, X., McBride, R., Rigter, A., Hanson, A., Zhong, G., Hatta, M., Xu, R., Yu, W., Kawaoka, Y., de Haan, C. A. M., Wilson, I. A., et al. Hemagglutinin receptor specificity and structural analyses of respiratory droplet-transmissible H5N1 viruses Journal of Virology  2014 88:768-773  DOI:10.1128/jvi.02690-13  PMID:24173215  PMCID:PMC3911709
  • Lee, P. S., Ohshima, N., Stanfield, R. L., Yu, W., Iba, Y., Okuno, Y., Kurosawa, Y., Wilson, I. A. Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus Nature Communications  2014 5:3614  DOI:10.1038/ncomms4614  PMID:24717798  PMCID:PMC4358779
  • Zhu, X., Guo, Y. H., Jiang, T., Wang, Y. D., Chan, K. H., Li, X. F., Yu, W., McBride, R., Paulson, J. C., Yuen, K. Y., Qin, C. F., Che, X. Y., et al. A unique and conserved neutralization epitope in H5N1 influenza viruses identified by an antibody against the A/Goose/Guangdong/1/96 hemagglutinin Journal of Virology  2013 87:12619-12635  DOI:10.1128/jvi.01577-13  PMID:24049169  PMCID:PMC3838140
  • Tong, S., Zhu, X., Li, Y., Shi, M., Zhang, J., Bourgeois, M., Yang, H., Chen, X., Recuenco, S., Gomez, J., Chen, L. M., Johnson, A., et al. New world bats harbor diverse influenza A viruses PLoS Pathogens  2013 9:e1003657  DOI:10.1371/journal.ppat.1003657  PMID:24130481  PMCID:PMC3794996
  • Xu, R., de Vries, R. P., Zhu, X., Nycholat, C. M., McBride, R., Yu, W., Paulson, J. C., Wilson, I. A. Preferential recognition of avian-like receptors in human influenza A H7N9 viruses Science  2013 342:1230-1235  DOI:10.1126/science.1243761  PMID:24311689  PMCID:PMC3954636
  • Wang, F., Ekiert, D. C., Ahmad, I., Yu, W., Zhang, Y., Bazirgan, O., Torkamani, A., Raudsepp, T., Mwangi, W., Criscitiello, M. F., Wilson, I. A., Schultz, P. G., et al. Reshaping antibody diversity Cell  2013 153:1379-1393  DOI:10.1016/j.cell.2013.04.049  PMID:23746848  PMCID:PMC4007204