authors

• Nicolaou, K.C.
• Yu, R.
• Shi, L.
• Cai, Q.
• Lu, M.
• Heretsch, P.

publication date

• April 2013

journal

• Organic Letters  Journal

abstract

• A three-step sequence to access functionalized 4,5-dihydrooxepines from cyclohexenones has been developed. This approach features a regioselective Baeyer-Villiger oxidation and subsequent functionalization via the corresponding enol phosphate intermediate.

subject areas

• Catalysis
• Combinatorial Chemistry Techniques
• Cyclohexanones
• Molecular Structure
• Oxepins
• Oxidation-Reduction
• Stereoisomerism

PubMed Central ID

• PMC3653422

International Standard Serial Number (ISSN)

• 1523-7052 (Electronic) 1523-7052 (Linking)

Digital Object Identifier (DOI)

• 10.1021/ol4006689

PubMed ID

• 23550898