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Amino acid derived quinazolines as Rock/PKA inhibitors

Academic Article
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Overview

authors

  • Chowdhury, S.
  • Chen, Y. T.
  • Fang, X. G.
  • Grant, W.
  • Pocas, J.
  • Cameron, Michael
  • Ruiz, C.
  • Lin, L.
  • Park, H.
  • Schroter, T.
  • Bannister, Thomas
  • LoGrasso, Philip
  • Feng, Yangbo

publication date

  • March 2013

journal

  • Bioorganic & Medicinal Chemistry Letters  Journal

subject areas

  • Amino Acids
  • Binding Sites
  • Cyclic AMP-Dependent Protein Kinases
  • Humans
  • Microsomes
  • Molecular Docking Simulation
  • Protein Binding
  • Protein Kinase Inhibitors
  • Protein Structure, Tertiary
  • Quinazolines
  • Structure-Activity Relationship
  • rho-Associated Kinases
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Research

keywords

  • Kinase inhibitor
  • PKA
  • Quinazoline
  • Rock
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Identity

International Standard Serial Number (ISSN)

  • 0960-894X

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2013.01.109

PubMed ID

  • 23416002
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Additional Document Info

start page

  • 1592

end page

  • 1599

volume

  • 23

issue

  • 6

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