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Integrated computational and experimental analysis of the neuroendocrine transcriptome in genetic hypertension identifies novel control points for the cardiometabolic syndrome

Academic Article
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Overview

authors

  • Friese, R. S.
  • Ye, C.
  • Nievergelt, C. M.
  • Schork, A. J.
  • Mahapatra, N. R.
  • Rao, F.
  • Napolitan, P. S.
  • Waalen, Jill
  • Ehret, G. B.
  • Munroe, P. B.
  • Schmid-Schonbein, G. W.
  • Eskin, E.
  • O'Connor, D. T.

publication date

  • August 2012

journal

  • Circulation-Cardiovascular Genetics  Journal

subject areas

  • Adrenal Glands
  • Animals
  • Base Sequence
  • Blood Pressure
  • Computational Biology
  • Enhancer Elements, Genetic
  • Genetic Predisposition to Disease
  • Humans
  • Hypertension
  • Luciferases
  • Male
  • Meta-Analysis as Topic
  • Metabolic Syndrome
  • Mice
  • Molecular Sequence Data
  • Myocardium
  • Neurosecretory Systems
  • Nucleotide Motifs
  • Oligonucleotide Array Sequence Analysis
  • Promoter Regions, Genetic
  • Protein Binding
  • RNA, Messenger
  • Transcription Factors
  • Transcription, Genetic
  • Transcriptional Activation
  • Transcriptome
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Research

keywords

  • BPH mouse strain
  • complex trait
  • essential (genetic) hypertension
  • human genetics
  • metabolic syndrome
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Identity

PubMed Central ID

  • PMC3467001

International Standard Serial Number (ISSN)

  • 1942-325X

Digital Object Identifier (DOI)

  • 10.1161/circgenetics.111.962415

PubMed ID

  • 22670052
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Additional Document Info

start page

  • 430

end page

  • 440

volume

  • 5

issue

  • 4

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