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Leg intramuscular pressures and in vivo knee forces during lower body positive and negative pressure treadmill exercise

Academic Article
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Overview

authors

  • Macias, B. R.
  • D'Lima, Darryl
  • Cutuk, A.
  • Patil, S.
  • Steklov, N.
  • Neuschwander, T. B.
  • Meuche, S.
  • Colwell Jr., Clifford
  • Hargens, A. R.

publication date

  • July 2012

journal

  • Journal of Applied Physiology  Journal

abstract

  • Quantifying muscle and joint forces over a broad range of weight bearing loads during exercise may provide data required to improve prosthetic materials and better protect against muscle and bone loss. Collectively, leg intramuscular pressure (IMP), ground reaction force (GRF), and the instrumented tibial tray force measurements provide a comprehensive assessment of leg muscle and joint biomechanical effects of gravity during exercise. Titration of body weight (BW) by lower body negative pressure (LBNP) and lower body positive pressure (LBPP) can reproducibly modulate IMP within leg muscle compartments. In addition, previous studies document peak tibial forces during various daily activities of 2.2 to 2.5 BW. The study objective was to determine the IMPs of the leg, axial compressive force on the tibia in vivo, vertical GRF, and knee range of motion during altered BW levels using LBPP and LBNP treadmill exercise. We hypothesize that peak GRF, peak tibial forces, and peak IMPs of the leg correlate linearly with percent BW, as generated across a broad range of upright LBPP and supine LBNP exercise. When running at 2.24 m/s the leg IMPs significantly increased over the loading range of 60% to 140% BW with LBPP and LBNP (P < 0.001); as expected, leg IMPs were significantly higher when running compared with standing (P < 0.001). During upright LBPP, total axial force at the knee increased linearly as a function of BW at 0.67 m/s (R(2) = 0.90) and 1.34 m/s (R(2) = 0.98). During supine LBNP, total axial force at the knee increased linearly as a function of BW at 0.67 m/s (R(2) = 0.98) and 1.34 m/s (R(2) = 0.91). The present study is the first to measure IMPs and peak tibial forces in vivo during upright LBPP, upright LBNP, and supine LBNP exercise. These data will aid the development of rehabilitation exercise hardware and prescriptions for patients and astronauts.

subject areas

  • Adolescent
  • Adult
  • Aged, 80 and over
  • Biomechanical Phenomena
  • Exercise Test
  • Female
  • Humans
  • Knee
  • Lower Body Negative Pressure
  • Male
  • Muscle, Skeletal
  • Pressure
  • Range of Motion, Articular
  • Running
  • Tibia
  • Young Adult
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Research

keywords

  • exercise countermeasure
  • ground reaction force
  • microgravity
  • prosthesis
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Identity

International Standard Serial Number (ISSN)

  • 8750-7587

Digital Object Identifier (DOI)

  • 10.1152/japplphysiol.01434.2011

PubMed ID

  • 22539171
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Additional Document Info

start page

  • 31

end page

  • 38

volume

  • 113

issue

  • 1

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