recent publications

• academic article

  • Tilstra, J. S., Gaddy, D. F., Zhao, J., Dave, S. H., Niedernhofer, L. J., Plevy, S. E., Robbins, P. D. Pharmacologic IKK/NF-kappa B inhibition causes antigen presenting cells to undergo TNF alpha dependent ROS-mediated programmed cell death Scientific Reports  2014 4:3631  DOI:10.1038/srep03631  PMID:24406986  PMCID:PMC3887388
  • Nasto, L. A., Seo, H. Y., Robinson, A. R., Tilstra, J. S., Clauson, C. L., Sowa, G. A., Ngo, K., Dong, Q., Pola, E., Lee, J. Y., Niedernhofer, L. J., Kang, J. D., et al. Issls prize winner: Inhibition of nf-kappa b activity ameliorates age-associated disc degeneration in a mouse model of accelerated aging Spine  2012 37:1819-1825  DOI:10.1097/BRS.0b013e31824ee8f7  PMID:22343279  PMCID:PMC3395770
  • Tilstra, J. S., Robinson, A. R., Wang, J., Gregg, S. Q., Clauson, C. L., Reay, D. P., Nasto, L. A., St Croix, C. M., Usas, A., Vo, N., Huard, J., Clemens, P. R., et al. NF-kB inhibition delays DNA damage-induced senescence and aging in mice Journal of Clinical Investigation  2012 122:2601-2612  DOI:10.1172/jci45785  PMID:22706308  PMCID:PMC3386805
  • Lu, A. P., Proto, J. D., Guo, L. L., Tang, Y., Lavasani, M., Tilstra, J. S., Niedernhofer, L. J., Wang, B., Guttridge, D. C., Robbins, P. D., Huard, J. NF-kB negatively impacts the myogenic potential of muscle-derived stem cells Molecular Therapy  2012 20:661-668  DOI:10.1038/mt.2011.261  PMID:22158056  PMCID:PMC3293604
  • Lavasani, M., Robinson, A. R., Lu, A. P., Song, M. J., Feduska, J. M., Ahani, B., Tilstra, J. S., Feldman, C. H., Robbins, P. D., Niedernhofer, L. J., Huard, J. Muscle-derived stem/progenitor cell dysfunction limits healthspan and lifespan in a murine progeria model Nature Communications  2012 3:608  DOI:10.1038/ncomms1611  PMID:22215083  PMCID:PMC3272577
  • Dave, S. H., Tilstra, J. S., Matsuoka, K., Li, F. L., Karrasch, T., Uno, J. K., Sepulveda, A. R., Jobin, C., Baldwin, A. S., Robbins, P. D., Plevy, S. E. Amelioration of chronic murine colitis by peptide-mediated transduction of the I kappa B kinase inhibitor NEMO binding domain peptide Journal of Immunology  2007 179:7852-7859  PMID:18025231  PMCID:PMC3203537