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Issls prize winner: Inhibition of nf-kappa b activity ameliorates age-associated disc degeneration in a mouse model of accelerated aging

Academic Article
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  • Research
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Overview

authors

  • Nasto, L. A.
  • Seo, H. Y.
  • Robinson, A. R.
  • Tilstra, J. S.
  • Clauson, C. L.
  • Sowa, G. A.
  • Ngo, K.
  • Dong, Q.
  • Pola, E.
  • Lee, Jiing-Dwan
  • Niedernhofer, Laura
  • Kang, J. D.
  • Robbins, Paul D.
  • Vo, N. V.

publication date

  • October 2012

journal

  • Spine  Journal

subject areas

  • Aging
  • Amino Acid Sequence
  • Animals
  • Awards and Prizes
  • DNA-Binding Proteins
  • Disease Models, Animal
  • Endonucleases
  • Female
  • Green Fluorescent Proteins
  • Humans
  • I-kappa B Kinase
  • Intervertebral Disc Degeneration
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Mice, Transgenic
  • Microscopy, Fluorescence
  • Molecular Sequence Data
  • NF-kappa B
  • Peptides
  • Proteoglycans
  • Transcription Factor RelA
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Research

keywords

  • DNA damage
  • Ercc1-deficient mice
  • NF-kB
  • aging
  • disc degeneration
  • proteoglycan
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Identity

PubMed Central ID

  • PMC3395770

International Standard Serial Number (ISSN)

  • 0362-2436

Digital Object Identifier (DOI)

  • 10.1097/BRS.0b013e31824ee8f7

PubMed ID

  • 22343279
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Additional Document Info

start page

  • 1819

end page

  • 1825

volume

  • 37

issue

  • 21

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