recent publications

• academic article

  • Zheng, Y. F., Zhu, M. H., Srinivasan, S., Nwachukwu, J. C., Cavett, V., Min, J., Carlson, K. E., Wang, P. C., Dong, C. N., Katzenellenbogen, J. A., Nettles, K. W., Zhou, H. B. Development of selective estrogen receptor modulator (SERM)-like activity through an indirect mechanism of estrogen receptor antagonism: Defining the binding mode of 7-oxabicyclo 2.2.1 hept-5-ene scaffold core ligands ChemMedChem  2012 7:1094-1100  DOI:10.1002/cmdc.201200048  PMID:22517684  PMCID:PMC4301955
  • Wang, P. C., Min, J., Nwachukwu, J. C., Cavett, V., Carlson, K. E., Guo, P., Zhu, M. H., Zheng, Y. F., Dong, C. N., Katzenellenbogen, J. A., Nettles, K. W., Zhou, H. B. Identification and structure-activity relationships of a novel series of estrogen receptor ligands based on 7-thiabicyclo 2.2.1 hept-2-ene-7-oxide Journal of Medicinal Chemistry  2012 55:2324-2341  DOI:10.1021/jm201556r  PMID:22283328  PMCID:PMC3297713
  • Zhu, M. H., Zhang, C., Nwachukwu, J. C., Srinivasan, S., Cavett, V., Zheng, Y. F., Carlson, K. E., Dong, C. N., Katzenellenbogen, J. A., Nettles, K. W., Zhou, H. B. Bicyclic core estrogens as full antagonists: Synthesis, biological evaluation and structure-activity relationships of estrogen receptor ligands based on bridged oxabicyclic core arylsulfonamides Organic & Biomolecular Chemistry  2012 10:8692-8700  DOI:10.1039/c2ob26531a  PMID:23033157  PMCID:PMC3500388