recent publications
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academic article
- Sun, Y., Liu, C. H., SanGiovanni, J. P., Evans, L. P., Tian, K. T., Zhang, B., Stahl, A., Pu, W. T., Kamenecka, T. M., Solt, L. A., Chen, J. Nuclear receptor RORα regulates pathologic retinal angiogenesis by modulating SOCS3-dependent inflammation Proceedings of the National Academy of Sciences of the United States of America 2015 112:10401-10406 DOI:10.1073/pnas.1504387112 PMID:26243880 PMCID:PMC4547221
- Cao, Y., Axup, J. Y., Ma, J. S. Y., Wang, R. E., Choi, S., Tardif, V., Lim, R. K. V., Pugh, H. M., Lawson, B. R., Welzel, G., Kazane, S. A., Sun, Y., et al. Multiformat T-cell-engaging bispecific antibodies targeting human breast cancers Angewandte Chemie-International Edition 2015 54:7022-7027 DOI:10.1002/anie.201500799 PMID:25919418 PMCID:PMC4492699
- Delhanty, P. J. D., van der Velde, M., van der Eerden, B. C. J., Sun, Y., Geminn, J. M. M., van der Lely, A. J., Smith, R. G., van Leeuwen, J. P. T. M. Genetic manipulation of the ghrelin signaling system in male mice reveals bone compartment specificity of acylated and unacylated ghrelin in the regulation of bone remodeling Endocrinology 2014 155:4287-4295 DOI:10.1210/en.2013-2055 PMID:25060361
- Kularatne, S. A., Deshmukh, V., Ma, J., Tardif, V., Lim, R. K. V., Pugh, H. M., Sun, Y., Manibusan, A., Sellers, A. J., Barnett, R. S., Srinagesh, S., Forsyth, J. S., et al. A CXCR4-targeted site-specific antibody-drug conjugate Angewandte Chemie-International Edition 2014 53:11863-11867 DOI:10.1002/anie.201408103 PMID:25213874 PMCID:PMC4331128
- Tian, F., Lu, Y., Manibusan, A., Sellers, A., Tran, H., Sun, Y., Phuong, T., Barnett, R., Hehli, B., Song, F., DeGuzman, M. J., Ensari, S., et al. A general approach to site-specific antibody drug conjugates Proceedings of the National Academy of Sciences of the United States of America 2014 111:1766-1771 DOI:10.1073/pnas.1321237111 PMID:24443552 PMCID:PMC3918752
- Kularatne, S. A., Deshmukh, V., Gymnopoulos, M., Biroc, S. L., Xia, J. M., Srinagesh, S., Sun, Y., Zou, N., Shimazu, M., Pinkstaff, J., Ensari, S., Knudsen, N., et al. Recruiting cytotoxic T cells to folate-receptor-positive cancer cells Angewandte Chemie-International Edition 2013 52:12101-12104 DOI:10.1002/anie.201306866 PMID:24573789 PMCID:PMC4012751
- Bian, M., Wang, Z., Xiong, X. C., Sun, Y., Matera, C., Nicolaou, K. C., Li, A. Total syntheses of anominine and tubingensin a Journal of the American Chemical Society 2012 134:8078-8081 DOI:10.1021/ja302765m PMID:22537293
- Singleton, K. L., Roybal, K. T., Sun, Y., Fu, G., Gascoigne, N. R. J., van Oers, N. S. C., Wulfing, C. Spatiotemporal patterning during t cell activation is highly diverse Science Signaling 2009 2:ra15 DOI:10.1126/scisignal.2000199 PMID:19351954 PMCID:PMC2694444
- Lee, C. W., Kim, N. H., Choi, H. K., Sun, Y., Nam, J. S., Rhee, H. J., Chun, J., Huh, S. O. Lysophosphatidic acid-induced c-fos up-regulation involves cyclic AMP response element-binding protein activated by mitogen- and stress-activated protein kinase-1 Journal of Cellular Biochemistry 2008 104:785-794 DOI:10.1002/jcb.21663 PMID:18172855
- Smith, R. G., Sun, Y., Jiang, H., Albarran-Zeckler, R., Timchenko, N. Ghrelin receptor (GHS-R1A) agonists show potential as interventive agents during aging Annals of the New York Academy of Sciences 2007 1119:147-164 DOI:10.1196/annals.1404.023 PMID:18056963
- Letvin, N. L., Mascola, J. R., Sun, Y., Gorgone, D. A., Buzby, A. P., Xu, L., Yang, Z. Y., Chakrabarti, B., Rao, S. S., Schmitz, J. E., Montefiori, D. C., Barker, B. R., et al. Preserved cd4(+) central memory t cells and survival in vaccinated siv-challenged monkeys Science 2006 312:1530-1533 DOI:10.1126/science.1124226 PMID:16763152 PMCID:PMC2365913
- Li, H., Liu, Y., Shin, S., Sun, Y., Loring, J. F., Mattson, M. P., Rao, M. S., Zhan, M. Transcriptome coexpression map of human embryonic stem cells BMC Genomics 2006 7:103 DOI:10.1186/1471-2164-7-103 PMID:16670017 PMCID:PMC1523211
- Sun, Y., Asnicar, M., Saha, P. K., Chan, L., Smith, R. G. Ablation of ghrelin improves the diabetic but not obese phenotype of ob/ob mice Cell Metabolism 2006 3:379-386 DOI:10.1016/j.cmet.2006.04.004 PMID:16679295
- Farzan, M., Choe, H., Desjardins, E., Sun, Y., Kuhn, J., Cao, J., Archambault, D., Kolchinsky, P., Koch, M., Wyatt, R., Sodroski, J. Stabilization of human immunodeficiency virus type 1 envelope glycoprotein trimers by disulfide bonds introduced into the gp41 glycoprotein ectodomain Journal of Virology 1998 72:7620-7625 PMID:9696864 PMCID:PMC110020
- Sullivan, N., Sun, Y., Binley, J., Lee, J., Barbas, C. F., Parren, Pwhi, Burton, D. R., Sodroski, J. Determinants of human immunodeficiency virus type 1 envelope glycoprotein activation by soluble cd4 and monoclonal antibodies Journal of Virology 1998 72:6332-6338 PMID:9658072 PMCID:PMC109776
- Choe, H., Farzan, M., Konkel, M., Martin, K., Sun, Y., Marcon, L., Cayabyab, M., Berman, M., Dorf, M. E., Gerard, N., Gerard, C., Sodroski, J. The orphan seven-transmembrane receptor apj supports the entry of primary T-cell-line-tropic and dualtropic human immunodeficiency virus type 1 Journal of Virology 1998 72:6113-6118 PMID:9621075 PMCID:PMC110417
- Rizzuto, C. D., Wyatt, R., Hernandez-Ramos, N., Sun, Y., Kwong, P. D., Hendrickson, W. A., Sodroski, J. A conserved hiv gp120 glycoprotein structure involved in chemokine receptor binding Science 1998 280:1949-1953 DOI:10.1126/science.280.5371.1949 PMID:9632396
- Farzan, M., Choe, H., Vaca, L., Martin, K., Sun, Y., Desjardins, E., Ruffing, N., Wu, L. J., Wyatt, R., Gerard, N., Gerard, C., Sodroski, J. A tyrosine-rich region in the N terminus of CCR5 is important for human immunodeficiency virus type 1 entry and mediates an association between gp120 and CCR5 Journal of Virology 1998 72:1160-1164 PMID:9445013 PMCID:PMC124591
- Farzan, M., Choe, H., Martin, K., Marcon, L., Hofmann, W., Karlsson, G., Sun, Y., Barrett, P., Marchand, N., Sullivan, N., Gerard, N., Gerard, C., et al. Two orphan seven-transmembrane segment receptors which are expressed in CD4-positive cells support simian immunodeficiency virus infection Journal of Experimental Medicine 1997 186:405-411 DOI:10.1084/jem.186.3.405 PMID:9236192 PMCID:PMC2198994
- Farzan, M., Choe, H., Martin, K. A., Sun, Y., Sidelko, M., Mackay, C. R., Gerard, N. P., Sodroski, J., Gerard, C. HIV-1 entry and macrophage inflammatory protein-1 beta-mediated signaling are independent functions of the chemokine receptor CCR5 Journal of Biological Chemistry 1997 272:6854-6857 PMID:9054370
- Choe, H., Farzan, M., Sun, Y., Sullivan, N., Rollins, B., Ponath, P. D., Wu, L. J., Mackay, C. R., LaRosa, G., Newman, W., Gerard, N., Gerard, C., et al. The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates Cell 1996 85:1135-1148 DOI:10.1016/s0092-8674(00)81313-6 PMID:8674119