recent publications
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academic article
- Nicolaou, K. C., Finlay, M. R. V., Ninkovic, S., King, N. P., He, Y., Li, T. H., Sarabia, F., Vourloumis, D. Synthesis and biological properties of C12,13-cyclopropylepothilone a and related epothilones Chemistry & Biology 1998 5:365-372 DOI:10.1016/s1074-5521(98)90070-9 PMID:9662505
- Nicolaou, K. C., Kim, S. H., Pfefferkorn, J., Xu, J. Y., Ohshima, T., Hosokawa, S., Vourloumis, D., Li, T. Synthesis and biological activity of sarcodictyins Angewandte Chemie-International Edition 1998 37:1418-1421 DOI:10.1002/(sici)1521-3773(19980605)37:10<1418::aid-anie1418>3.0.co;2-5
- Nicolaou, K. C.*, He, Y.*, Roschangar, F., King, N. P., Vourloumis, D., Li, T. H. Total synthesis of epothilone e and analogues with modified side chains through the stille coupling reaction Angewandte Chemie-International Edition 1998 37:84-87 DOI:10.1002/(sici)1521-3773(19980202)37:1/2<84::aid-anie84>3.3.co;2-m (* = equal contribution)
- Nicolaou, K. C., Ninkovic, S., Finlay, M. R. V., Sarabia, F., Li, T. H. Total synthesis of 26-hydroxyepothilone b and related analogues Chemical Communications 1997 2343-2344 DOI:10.1039/a705845d
- Li, T. H., Weinstein, D. S., Nicolaou, K. C. The chemical end-ligation of homopyrimidine oligodeoxyribonucleotides within a DNA triple helix Chemistry & Biology 1997 4:209-214 DOI:10.1016/s1074-5521(97)90290-8 PMID:9115413
- Nicolaou, K. C., Vourloumis, D., Li, T. H., Pastor, J., Winssinger, N., He, Y., Ninkovic, S., Sarabia, F., Vallberg, H., Roschangar, F., King, N. P., Finlay, M. R. V., et al. Designed epothilones: Combinatorial synthesis, tubulin assembly properties, and cytotoxic action against taxol-resistant tumor cells Angewandte Chemie-International Edition 1997 36:2097-2103 DOI:10.1002/anie.199720971
- Nicolaou, K. C., vanDelft, F., Ohshima, T., Vourloumis, D., Xu, J. Y., Hosokawa, S., Pfefferkorn, J., Kim, S., Li, T. H. Total synthesis of eleutherobin Angewandte Chemie-International Edition 1997 36:2520-2524 DOI:10.1002/anie.199725201
- Liu, C., Smith, B. M., Ajito, K., Komatsu, H., GomezPaloma, L., Li, T. H., Theodorakis, E. A., Nicolaou, K. C., Vogt, P. K. Sequence-selective carbohydrate DNA interaction: Dimeric and monomeric forms of the calicheamicin oligosaccharide interfere with transcription factor function Proceedings of the National Academy of Sciences of the United States of America 1996 93:940-944 DOI:10.1073/pnas.93.2.940 PMID:8570664
- Nicolaou, K. C., Ajito, K., Komatsu, H., Smith, B. M., Li, T. H., Egan, M. G., Gomezpaloma, L. DNA-carbohydrate recognition - design and synthesis of an 8-base sequence-selective DNA-binding oligosaccharide Angewandte Chemie-International Edition 1995 34:576-578 DOI:10.1002/anie.199505761
- Li, T. H., Zeng, Z. J., Estevez, V. A., Baldenius, K. U., Nicolaou, K. C., Joyce, G. F. Carbohydrate minor-groove interactions in the binding of calicheamicin gamma-1(i) to duplex DNA Journal of the American Chemical Society 1994 116:3709-3715 DOI:10.1021/ja00088a006