recent publications
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academic article
- Li, L. S., Sinha, S. C. Studies toward the duocarmycin prodrugs for the antibody prodrug therapy approach Tetrahedron Letters 2009 50:2932-2935 DOI:10.1016/j.tetlet.2009.03.205 PMID:20160897 PMCID:PMC2768327
- Abraham, S., Guo, F., Li, L. S., Rader, C., Liu, C., Barbas, C. F., 3rd, Lerner, R. A., Sinha, S. C. Synthesis of the next-generation therapeutic antibodies that combine cell targeting and antibody-catalyzed prodrug activation Proceedings of the National Academy of Sciences of the United States of America 2007 104:5584-5589 DOI:10.1073/pnas.0700223104 PMID:17372220 PMCID:PMC1838444
- Sinha, S. C., Das, S., Li, L. S., Lerner, R. A., Barbas, C. F. Preparation of integrin alpha(v) beta(3)-targeting ab 38c2 constructs Nature Protocols 2007 2:449-456 DOI:10.1038/nprot.2007.3 PMID:17406606
- Li, L. S., Babendure, J. L., Sinha, S. C., Olefsky, J. M., Lerner, R. A. Synthesis and evaluation of photolabile insulin prodrugs Bioorganic & Medicinal Chemistry Letters 2005 15:3917-3920 DOI:10.1016/j.bmcl.2005.05.112 PMID:15993597
- Das, S., Li, L. S., Abraham, S., Chen, Z. Y., Sinha, S. C. A bidirectional approach to the synthesis of a complete library of adjacent-bis-thf annonaceous acetogenins Journal of Organic Chemistry 2005 70:5922-5931 DOI:10.1021/jo050697c PMID:16018687
- Li, L. S., Rader, C., Matsushita, M., Das, S., Barbas, C. F., Lerner, R. A., Sinha, S. C. Chemical adaptor immunotherapy: design, synthesis, and evaluation of novel integrin-targeting devices Journal of Medicinal Chemistry 2004 47:5630-5640 DOI:10.1021/jm049666k PMID:15509162
- Sinha, S. C., Li, L. S., Watanabe, S., Kaltgrad, E., Tanaka, F., Rader, C., Lerner, R. A., Barbas, C. F. Aldolase antibody activation of prodrugs of potent aldehyde-containing cytotoxics for selective chemotherapy Chemistry-a European Journal 2004 10:5467-5472 DOI:10.1002/chem.200400419 PMID:15378729
- Sinha, S. C., Li, L. S., Miller, G. P., Dutta, S., Rader, C., Lerner, R. A. Prodrugs of dynemicin analogs for selective chemotherapy mediated by an aldolase catalytic Ab Proceedings of the National Academy of Sciences of the United States of America 2004 101:3095-3099 DOI:10.1073/pnas.0307319101 PMID:14981258 PMCID:PMC365749
- Li, L. S., Das, S., Sinha, S. C. Efficient one-step aldol-type reaction of ketones with acetals and ketals mediated by dibutylboron triflate/diisopropylethyl amine Organic Letters 2004 6:127-130 DOI:10.1021/ol030108u PMID:14703367
- Das, S., Li, L. S., Sinha, S. C. Stereloselective aldol-type cyclization reaction mediated by dibutylboron triflate/diisopropylethylamine Organic Letters 2004 6:123-126 DOI:10.1021/ol036229b PMID:14703366