recent publications

• academic article

  • Huang, C. Y., Shih, H. W., Lin, L. Y., Tien, Y. W., Cheng, T. J. R., Cheng, W. C., Wong, C. H., Ma, C. Crystal structure of staphylococcus aureus transglycosylase in complex with a lipid ii analog and elucidation of peptidoglycan synthesis mechanism Proceedings of the National Academy of Sciences of the United States of America  2012 109:6496-6501  DOI:10.1073/pnas.1203900109  PMID:22493270  PMCID:PMC3340074
  • Shih, H. W., Chang, Y. F., Li, W. J., Meng, F. C., Huang, C. Y., Ma, C., Cheng, T. J. R., Wong, C. H., Cheng, W. C. Effect of the peptide moiety of lipid ii on bacterial transglycosylase Angewandte Chemie-International Edition  2012 51:10123-10126  DOI:10.1002/anie.201204038  PMID:22952114
  • Shih, H. W., Chen, K. T., Chen, S. K., Huang, C. Y., Cheng, T. J. R., Ma, C., Wong, C. H., Cheng, W. C. Combinatorial approach toward synthesis of small molecule libraries as bacterial transglycosylase inhibitors Organic & Biomolecular Chemistry  2010 8:2586-2593  DOI:10.1039/c000622j  PMID:20485795
  • Sung, M. T., Lai, Y. T., Huang, C. Y., Chou, L. Y., Shih, H. W., Cheng, W. C., Wong, C. H., Ma, C. Crystal structure of the membrane-bound bifunctional transglycosylase pbp1b from escherichia coli Proceedings of the National Academy of Sciences of the United States of America  2009 106:8824-8829  DOI:10.1073/pnas.0904030106  PMID:19458048  PMCID:PMC2689995
  • Cheng, T. J. R., Sung, M. T., Liao, H. Y., Chang, Y. F., Chen, C. W., Huang, C. Y., Chou, L. Y., Wu, Y. D., Chen, Y., Cheng, Y. S. E., Wong, C. H., Ma, C., et al. Domain requirement of moenomycin binding to bifunctional transglycosylases and development of high-throughput discovery of antibiotics Proceedings of the National Academy of Sciences of the United States of America  2008 105:431-436  DOI:10.1073/pnas.0710868105  PMID:18182485  PMCID:PMC2206553