recent publications
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academic article
- Kumar, K. R., Lohmann, K., Masuho, I., Miyamoto, R., Ferbert, A., Lohnau, T., Kasten, M., Hagenah, J., Bruggemann, N., Graf, J., Munchau, A., Kostic, V. S., et al. Mutations in GNAL: a novel cause of craniocervical dystonia JAMA Neurology 2014 71:490-494 DOI:10.1001/jamaneurol.2013.4677 PMID:24535567 PMCID:PMC4237020
- Numa, M. M. D., Lee, L. V., Hsu, C. C., Bower, K. E., Wong, C. H. Identification of novel anthrax lethal factor inhibitors generated by combinatorial pictet-spengler reaction followed by screening in situ ChemBioChem 2005 6:1002-1006 DOI:10.1002/cbic.20050000 PMID:15880659
- Fridman, M., Belakhov, V., Lee, L. V., Liang, F. S., Wong, C. H., Baasov, T. Dual effect of synthetic aminoglycosides: Antibacterial activity against bacillus anthracis and inhibition of anthrax lethal factor Angewandte Chemie-International Edition 2005 44:447-452 DOI:10.1002/anie.200462003 PMID:15624157
- Mocharla, V. P., Colasson, B., Lee, L. V., Roper, S., Sharpless, K. B., Wong, C. H., Kolb, H. C. In situ click chemistry: Enzyme-generated inhibitors of carbonic anhydrase ii Angewandte Chemie-International Edition 2005 44:116-120 DOI:10.1002/anie.200461580
- Bryan, M. C., Lee, L. V., Wong, C. H. High-throughput identification of fucosyltransferase inhibitors using carbohydrate microarrays Bioorganic & Medicinal Chemistry Letters 2004 14:3185-3188 DOI:10.1016/j.bmcl.2004.04.001 PMID:15149672
- Best, M. D., Brik, A., Chapman, E., Lee, L. V., Cheng, W. C., Wong, C. H. Rapid discovery of potent sulfotransferase inhibitors by diversity-oriented reaction in microplates followed by in situ screening ChemBioChem 2004 5:811-819 DOI:10.1002/cbic.200300841 PMID:15174164
- Lee, L. V., Bower, K. E., Liang, F. S., Shi, J., Wu, D., Sucheck, S. J., Vogt, P. K., Wong, C. H. Inhibition of the proteolytic activity of anthrax lethal factor by aminoglycosides Journal of the American Chemical Society 2004 126:4774-4775 DOI:10.1021/ja0495359 PMID:15080670
- Lee, L. V., Mitchell, M. L., Huang, S. J., Fokin, V. V., Sharpless, K. B., Wong, C. H. A potent and highly selective inhibitor of human α-1,3-fucosyltransferase via click chemistry Journal of the American Chemical Society 2003 125:9588-9589 DOI:10.1021/ja0302836 PMID:12904015
- Mitchell, M. L., Lee, L. V., Wong, C. H. Synthesis and evaluation of six-membered GDP-iminocyclitol Tetrahedron Letters 2002 43:5691-5693 DOI:10.1016/s0040-4039(02)01108-5
- Mitchell, M. L., Tian, F., Lee, L. V., Wong, C. H. Synthesis and evaluation of transition-state analogue inhibitors of α-1,3-fucosyltransferase Angewandte Chemie-International Edition 2002 41:3041-3044 DOI:10.1002/1521-3773(20020816)41:16<3041::aid-anie3041>3.0.co;2-v PMID:12203452