recent publications

• academic article

  • Kumar, K. R., Lohmann, K., Masuho, I., Miyamoto, R., Ferbert, A., Lohnau, T., Kasten, M., Hagenah, J., Bruggemann, N., Graf, J., Munchau, A., Kostic, V. S., et al. Mutations in GNAL: a novel cause of craniocervical dystonia JAMA Neurology  2014 71:490-494  DOI:10.1001/jamaneurol.2013.4677  PMID:24535567  PMCID:PMC4237020
  • Fridman, M., Belakhov, V., Lee, L. V., Liang, F. S., Wong, C. H., Baasov, T. Dual effect of synthetic aminoglycosides: Antibacterial activity against bacillus anthracis and inhibition of anthrax lethal factor Angewandte Chemie-International Edition  2005 44:447-452  DOI:10.1002/anie.200462003  PMID:15624157
  • Numa, M. M. D., Lee, L. V., Hsu, C. C., Bower, K. E., Wong, C. H. Identification of novel anthrax lethal factor inhibitors generated by combinatorial pictet-spengler reaction followed by screening in situ ChemBioChem  2005 6:1002-1006  DOI:10.1002/cbic.20050000  PMID:15880659
  • Mocharla, V. P., Colasson, B., Lee, L. V., Roper, S., Sharpless, K. B., Wong, C. H., Kolb, H. C. In situ click chemistry: Enzyme-generated inhibitors of carbonic anhydrase ii Angewandte Chemie-International Edition  2005 44:116-120  DOI:10.1002/anie.200461580
  • Bryan, M. C., Lee, L. V., Wong, C. H. High-throughput identification of fucosyltransferase inhibitors using carbohydrate microarrays Bioorganic & Medicinal Chemistry Letters  2004 14:3185-3188  DOI:10.1016/j.bmcl.2004.04.001  PMID:15149672
  • Lee, L. V., Bower, K. E., Liang, F. S., Shi, J., Wu, D., Sucheck, S. J., Vogt, P. K., Wong, C. H. Inhibition of the proteolytic activity of anthrax lethal factor by aminoglycosides Journal of the American Chemical Society  2004 126:4774-4775  DOI:10.1021/ja0495359  PMID:15080670
  • Best, M. D., Brik, A., Chapman, E., Lee, L. V., Cheng, W. C., Wong, C. H. Rapid discovery of potent sulfotransferase inhibitors by diversity-oriented reaction in microplates followed by in situ screening ChemBioChem  2004 5:811-819  DOI:10.1002/cbic.200300841  PMID:15174164
  • Lee, L. V., Mitchell, M. L., Huang, S. J., Fokin, V. V., Sharpless, K. B., Wong, C. H. A potent and highly selective inhibitor of human α-1,3-fucosyltransferase via click chemistry Journal of the American Chemical Society  2003 125:9588-9589  DOI:10.1021/ja0302836  PMID:12904015
  • Mitchell, M. L., Lee, L. V., Wong, C. H. Synthesis and evaluation of six-membered GDP-iminocyclitol Tetrahedron Letters  2002 43:5691-5693  DOI:10.1016/s0040-4039(02)01108-5
  • Mitchell, M. L., Tian, F., Lee, L. V., Wong, C. H. Synthesis and evaluation of transition-state analogue inhibitors of α-1,3-fucosyltransferase Angewandte Chemie-International Edition  2002 41:3041-3044  DOI:10.1002/1521-3773(20020816)41:16<3041::aid-anie3041>3.0.co;2-v  PMID:12203452